W. Zeng

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Highly Immunogenic and Totally Synthetic Lipopeptides as Self-Adjuvanting Immunocontraceptive Vaccines1

L. Brown, D. Jackson, W. Zeng, 2002, The Journal of Immunology.

Synthetic peptide epitope-based polymers: controlling size and determining the efficiency of epitope incorporation.

D. Jackson, W. Zeng, K. Sadler, 2002, The journal of peptide research : official journal of the American Peptide Society.

A totally synthetic vaccine of generic structure that targets TLR2+ dendritic cells and promotes either antibody or CTL responses.

Corey Smith, L. Brown, D. Jackson, 2004 .

Dendritic cell acquisition of epitope cargo mediated by simple cationic peptide structures

D. Jackson, W. Zeng, D. Poole, 2008, Peptides.

Simple Branched Arginine-Based Structures can Enhance the Cellular Uptake of Peptide Cargos

D. Jackson, W. Zeng, B. Chua, 2007, International Journal of Peptide Research and Therapeutics.

Exploiting Information Inherent in Binding Sites of Virus-Specific Antibodies: Design of An HCV Vaccine Candidate Cross-Reactive with Multiple Genotypes

D. Jackson, W. Zeng, H. Drummer, 2006, Antiviral therapy.

New multi-determinant strategy for a group A streptococcal vaccine designed for the Australian Aboriginal population

D. Jackson, W. Zeng, M. Batzloff, 2000, Nature Medicine.

Intranasal Administration of the TLR 2 Agonist Pam 2 Cys Provides Rapid Protection against In fl uenza in Mice

J. McVernon, L. Brown, D. Jackson, 2012 .

Intranasal administration of the TLR2 agonist Pam2Cys provides rapid protection against influenza in mice.

J. McVernon, L. Brown, D. Jackson, 2012, Molecular pharmaceutics.

Geometry of a TLR2-Agonist-Based Adjuvant Can Affect the Resulting Antigen-Specific Immune Response.

D. Jackson, W. Zeng, B. Chua, 2019, Molecular pharmaceutics.

In Vivo Imaging of Bioluminescent Mycobacterium ulcerans: A Tool to Refine the Murine Buruli Ulcer Tail Model.

D. Jackson, W. Zeng, T. S. van der Werf, 2019, The American journal of tropical medicine and hygiene.

Mycobacterium ulcerans low infectious dose and atypical mechanical transmission support insect bites and puncturing injuries in the spread of Buruli ulcer

B. Howden, W. Zeng, J. Axford, 2016, bioRxiv.

Electrostatic-mediated enhancement of protein antigen immunogenicity using charged TLR2-targeting lipopeptides

S. Turner, D. Jackson, W. Zeng, 2012 .

Soluble Proteins Induce Strong CD8+ T Cell and Antibody Responses through Electrostatic Association with Simple Cationic or Anionic Lipopeptides That Target TLR2

S. Turner, D. Jackson, W. Zeng, 2011, The Journal of Immunology.

Synthesis of toll-like receptor-2 targeting lipopeptides as self-adjuvanting vaccines.

D. Jackson, W. Zeng, B. Chua, 2008, Methods in molecular biology.

Comparison of lipopeptide-based immunocontraceptive vaccines containing different lipid groups.

D. Jackson, W. Zeng, Yuk-Fai Lau, 2007, Vaccine.

A lipidated peptide of Mycobacterium tuberculosis resuscitates the protective efficacy of BCG vaccine by evoking memory T cell immunity

D. Jackson, W. Zeng, S. K. Maurya, 2017, Journal of Translational Medicine.

Lipidated promiscuous peptide augments the expression of MHC-II molecules on dendritic cells and activates T cells

D. Jackson, W. Zeng, J. Agrewala, 2013, The Indian journal of medical research.

Vaccine-Specific Immune Responses against Mycobacterium ulcerans Infection in a Low-Dose Murine Challenge Model

Kylie M. Quinn, K. Kedzierska, D. Jackson, 2019, Infection and Immunity.

Vaccine-Specific Immune Responses against Mycobacterium ulcerans Infection in a Low-Dose Murine Challenge Model

Kylie M. Quinn, K. Kedzierska, D. Jackson, 2019, Infection and Immunity.

The central role played by peptides in the immune response and the design of peptide-based vaccines against infectious diseases and cancer.

A. Purcell, D. Jackson, C. Fitzmaurice, 2002, Current drug targets.

Modulating Contact Lens Discomfort With Anti-Inflammatory Approaches: A Randomized Controlled Trial.

A. Vingrys, D. Jackson, W. Zeng, 2018, Investigative ophthalmology & visual science.

Bioluminscent Mycobacterium ulcerans, a tool to study host-pathogen interactions in a murine tail model of Buruli ulcer

D. Jackson, W. Zeng, T. S. van der Werf, 2018, bioRxiv.

Promiscuous peptide of 16 kDa antigen linked to Pam2Cys protects against Mycobacterium tuberculosis by evoking enduring memory T-cell response.

D. Jackson, W. Zeng, Vijender Singh, 2011, The Journal of infectious diseases.

Effects on Rotavirus Cell Binding and Infection of Monomeric and Polymeric Peptides Containing α2β1 and αxβ2 Integrin Ligand Sequences

Y. Takada, D. Jackson, W. Zeng, 2004, Journal of Virology.

Synthetic Peptide and Their Polymers as Vaccomes

L. Brown, D. Jackson, C. Fitzmaurice, 2002 .

Assembly of synthetic peptide vaccines by chemoselective ligation of epitopes: influence of different chemical linkages and epitope orientations on biological activity.

D. Jackson, W. Zeng, J. Pagnon, 2001, Vaccine.

SYNTHETIC PEPTIDE AND THEIR POLYMERS AS VACCINES Synthetic Peptide Polymers as the Next Generation of Vaccines

L. Brown, D. Jackson, C. Fitzmaurice, 2001 .

Totally synthetic lipid-containing polyoxime peptide constructs are potent immunogens.

K. Rose, L. Brown, D. Jackson, 2000, Vaccine.

Preparation and properties of totally synthetic immunogens.

L. Brown, D. Jackson, C. Fitzmaurice, 1999, Vaccine.

Synthesis of a New Template with a Built‐in Adjuvant and Its Use in Constructing Peptide Vaccine Candidates Through Polyoxime Chemistry

W. Zeng, D. Jackson, K. Rose, 1996, Journal of peptide science : an official publication of the European Peptide Society.

Polyoximes: A flexible approach for producing homogeneous artificial proteins

K. Rose, W. Zeng, D. C. Jackson, 1995 .

A synthetic peptide-based polyoxime vaccine construct of high purity and activity.

K. Rose, L. Brown, D. Jackson, 1995, Molecular immunology.

Lipidation of intact proteins produces highly immunogenic vaccine candidates.

D. Jackson, W. Zeng, A. Lew, 2011, Molecular immunology.

A self‐adjuvanting multiepitope immunogen that induces a broadly cross‐reactive antibody to hepatitis C virus

W. Zeng, H. Drummer, J. Torresi, 2007, Hepatology.

Cornea Modulating Contact Lens Discomfort With Anti-Inflammatory Approaches : A Randomized Controlled Trial

A. Vingrys, D. Jackson, W. Zeng, 2018 .

Intranasal lipopeptide primes lung‐resident memory CD8+ T cells for long‐term pulmonary protection against influenza

K. Kedzierska, S. Turner, L. Brown, 2006, European journal of immunology.

Maturation of dendritic cells with lipopeptides that represent vaccine candidates for hepatitis C virus

L. Brown, D. Jackson, W. Zeng, 2003, Immunology and cell biology.

Polyfunctional CD8(+) T cells are associated with the vaccination-induced control of a novel recombinant influenza virus expressing an HCV epitope.

K. Kedzierska, S. Valkenburg, D. Jackson, 2012, Antiviral research.

Induction of Long-Term Memory CD8 (cid:1) T Cells for Recall of Viral Clearing Responses against Inﬂuenza Virus

L. Brown, W. Zeng, G. Deliyannis, 2002 .

Lipopeptide vaccines: a strategy for improving protective immunity against influenza

A. Kelso, L. Brown, D. Jackson, 2001 .

This information is current as Influenza A Viruses Activation by Peptides and Engineered CTL + Affinity Thresholds for Naive CD 8

P. Doherty, S. Turner, J. Rossjohn, 2011 .

LymphocytesFacilitating Their Presentation to CD4 T Activate NK Cells via TLR2, Thus Herpes Simplex Virus Antigens Directly

W. Zeng, A. Cunningham, Min Kim, 2012 .

Parenteral and mucosal delivery of a novel multi-epitope M protein-based group A streptococcal vaccine construct: investigation of immunogenicity in mice.

D. Jackson, W. Zeng, M. Batzloff, 2002, Vaccine.

Bioactivity in an Aggrecan 32‐mer Fragment Is Mediated via Toll‐like Receptor 2

W. Zeng, P. Sutton, A. Fosang, 2015, Arthritis & rheumatology.

Structural requirement for the agonist activity of the TLR2 ligand Pam2Cys

D. Jackson, W. Zeng, B. Chua, 2010, Amino Acids.

Characterisation of the antibody response to a totally synthetic immunocontraceptive peptide vaccine based on LHRH.

D. Jackson, W. Zeng, Souravi Ghosh, 2005, Vaccine.

A lipidated form of the extracellular domain of influenza M2 protein as a self-adjuvanting vaccine candidate.

D. Jackson, W. Zeng, A. Tan, 2015, Vaccine.

Target TLR2 Cationic or Anionic Lipopeptides That Electrostatic Association with Simple and Antibody Responses through T Cell + Soluble Proteins Induce Strong CD8

S. Turner, W. Zeng, David Pejoski, 2011 .

9-Hydroxy-9-(4-carboxyphenyl)xanthene — A new linker for the synthesis of peptide amides

W. Zeng, E. Bayer, B. Henkel, 1997 .

Protection against heterologous human papillomavirus challenge by a synthetic lipopeptide vaccine containing a broadly cross-neutralizing epitope of L2

R. Roden, J. Schiller, D. Jackson, 2008, Proceedings of the National Academy of Sciences.

Totally synthetic peptide-based immunocontraceptive vaccines show activity in dogs of different breeds.

D. Jackson, W. Zeng, J. Pagnon, 2007, Vaccine.

An alkaloid from Corydalis bungeana

W. Zeng, Cunheng He, Q. Zheng, 1988 .

Affinity Thresholds for Naive CD8+ CTL Activation by Peptides and Engineered Influenza A Viruses

P. Doherty, S. Turner, J. Rossjohn, 2011, The Journal of Immunology.

T cell epitopes of the La/SSB autoantigen in humanized transgenic mice expressing the HLA class II haplotype DRB1*0301/DQB1*0201.

J. McCluskey, D. Jackson, W. Zeng, 2007, Arthritis and rheumatism.

Herpes Simplex Virus Antigens Directly Activate NK Cells via TLR2, Thus Facilitating Their Presentation to CD4 T Lymphocytes

D. Jackson, W. Zeng, A. Cunningham, 2012, The Journal of Immunology.

Activation of the NLRP3 Inflammasome by IAV Virulence Protein PB1-F2 Contributes to Severe Pathophysiology and Disease

E. Latz, M. Tate, L. Brown, 2013, PLoS pathogens.

Lipid-containing mimetics of natural triggers of innate immunity as CTL-inducing influenza vaccines.

L. Brown, D. Jackson, W. Zeng, 2006, International immunology.

Identification of antigenically active tryptic fragments of apical membrane antigen-1 (AMA1) of Plasmodium chabaudi malaria: strategies for assembly of immunologically active peptides.

R. Anders, L. Brown, D. Jackson, 2002, Vaccine.

Mycobacterium ulcerans low infectious dose and mechanical transmission support insect bites and puncturing injuries in the spread of Buruli ulcer

B. Howden, W. Zeng, J. Axford, 2017, PLoS neglected tropical diseases.

Different Arms of the Adaptive Immune System Induced by a Combination Vaccine Work in Concert to Provide Enhanced Clearance of Influenza

L. Brown, D. Jackson, W. Zeng, 2014, PloS one.

The Context of Epitope Presentation Can Influence Functional Quality of Recalled Influenza A Virus-Specific Memory CD8+ T Cells1

P. Doherty, K. Kedzierska, S. Turner, 2007, The Journal of Immunology.

Influenza A Virus-Specific Memory CD 8 Influence Functional Quality of Recalled The Context of Epitope Presentation

P. Doherty, K. Kedzierska, S. Turner, 2007 .

Human CD8+ T cell cross-reactivity across influenza A, B and C viruses

David F. Boyd, S. Tangye, F. Luciani, 2019, Nature Immunology.

The design and proof of concept for a CD8+ T cell‐based vaccine inducing cross‐subtype protection against influenza A virus

L. Brown, W. Zeng, G. Deliyannis, 2013, Immunology and cell biology.

Lipopeptide vaccines illustrate the potential role of subtype‐crossreactive T cells in the control of highly virulent influenza

L. Brown, D. Jackson, W. Zeng, 2009, Influenza and other respiratory viruses.

The Influenza Virus–Specific CTL Immunodominance Hierarchy in Mice Is Determined by the Relative Frequency of High-Avidity T Cells

P. Doherty, S. Turner, N. L. La Gruta, 2014, The Journal of Immunology.

Antigen-Driven Patterns of TCR Bias Are Shared across Diverse Outcomes of Human Hepatitis C Virus Infection

M. Hellard, C. Aitken, J. McCluskey, 2011, The Journal of Immunology.

Hepatitis C Virus Infection Shared across Diverse Outcomes of Human Antigen-Driven Patterns of TCR Bias Are

M. Hellard, C. Aitken, J. McCluskey, 2010 .

Dissecting the role of peptides in the immune response: theory, practice and the application to vaccine design

L. K. Ely, N. Mifsud, A. Purcell, 2003, Journal of peptide science : an official publication of the European Peptide Society.

Modular platforms for the assembly of self-adjuvanting lipopeptide-based vaccines for use in an out-bred population.

D. Jackson, W. Zeng, B. Chua, 2019, Vaccine.

The C-terminal pentapeptide of LHRH is a dominant B cell epitope with antigenic and biological function.

D. Jackson, W. Zeng, J. Pagnon, 2007, Molecular immunology.

Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model

D. Jackson, W. Zeng, M. Carroll, 2020, bioRxiv.

Totally synthetic peptide-based vaccines that target dendritic cells and induce potent antibody or CTL responses

D. Jackson, W. Zeng, B. Chua, 2006 .

Precursor Frequency and Competition Dictate the HLA-A2–Restricted CD8+ T Cell Responses to Influenza A Infection and Vaccination in HLA-A2.1 Transgenic Mice

N. L. La Gruta, W. Zeng, D. Jackson, 2011, The Journal of Immunology.

Vaccination in HLA-A2.1 Transgenic Mice Responses to Influenza A Infection and T Cell + Restricted CD8 - Dictate the HLA-A2 Precursor Frequency and Competition

N. Gruta, D. Jackson, W. Zeng, 2011 .

A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses.

Corey Smith, A. Suhrbier, L. Brown, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Branched and linear lipopeptide vaccines have different effects on primary CD4+ and CD8+ T-cell activation but induce similar tumor-protective memory CD8+ T-cell responses.

A. Kelso, D. Jackson, W. Zeng, 2008, Vaccine.

Induction of Long-Term Memory CD8+ T Cells for Recall of Viral Clearing Responses against Influenza Virus

L. Brown, D. Jackson, N. Ede, 2002, Journal of Virology.

Intranasal vaccination with a lipopeptide containing a conformationally constrained conserved minimal peptide, a universal T cell epitope, and a self-adjuvanting lipid protects mice from group A streptococcus challenge and reduces throat colonization.

D. Jackson, W. Zeng, M. Batzloff, 2006, The Journal of infectious diseases.

A self-adjuvanting lipopeptide-based vaccine candidate for the treatment of hepatitis C virus infection.

L. Brown, D. Jackson, W. Zeng, 2008, Vaccine.

Induction of neutralizing antibody responses to hepatitis C virus with synthetic peptide constructs incorporating both antibody and T‐helper epitopes

W. Zeng, H. Drummer, J. Torresi, 2007, Immunology and cell biology.

A Modular Approach to Assembly of Totally Synthetic Self-adjuvanting Lipopeptide-based Vaccines Allows Conformational Epitope Building*

W. Zeng, R. Robins-Browne, Kristy I Azzopardi, 2011, The Journal of Biological Chemistry.

Identification of dominant epitopes of synthetic immunocontraceptive vaccines that induce antibodies in dogs.

D. Jackson, W. Zeng, J. Pagnon, 2005, Vaccine.

Chitosan microparticles and nanoparticles as biocompatible delivery vehicles for peptide and protein-based immunocontraceptive vaccines.

W. Zeng, D. Mainwaring, B. Chua, 2012, Molecular pharmaceutics.

PEGylation of a TLR2-agonist-based vaccine delivery system improves antigen trafficking and the magnitude of ensuing antibody and CD8+ T cell responses.

C. Sugimoto, D. Jackson, W. Zeng, 2017, Biomaterials.

A novel therapeutic strategy of lipidated promiscuous peptide against Mycobacterium tuberculosis by eliciting Th1 and Th17 immunity of host

D. Jackson, W. Zeng, S. K. Maurya, 2016, Scientific Reports.

A totally synthetic lipopeptide-based self-adjuvanting vaccine induces neutralizing antibodies against heat-stable enterotoxin from enterotoxigenic Escherichia coli.

D. Jackson, W. Zeng, R. Robins-Browne, 2012, Vaccine.

TLR2-mediated activation of innate responses in the upper airways confers antiviral protection of the lungs

Nichollas E. Scott, K. Kedzierska, L. Brown, 2021, JCI insight.

A lipidated peptide of Mycobacterium tuberculosis resuscitates the protective efficacy of BCG vaccine by evoking memory T cell immunity

D. Jackson, W. Zeng, S. K. Maurya, 2017, Journal of Translational Medicine.

A lipopeptide based on the M2 and HA proteins of influenza A viruses induces protective antibody

S. Rockman, L. Brown, W. Zeng, 2010, Immunology and cell biology.

A lipidated bi-epitope vaccine comprising of MHC-I and MHC-II binder peptides elicits protective CD4 T cell and CD8 T cell immunity against Mycobacterium tuberculosis

D. Jackson, W. Zeng, S. K. Maurya, 2018, Journal of Translational Medicine.

Human CD8+ T cell cross-reactivity across influenza A, B and C viruses

David F. Boyd, S. Tangye, F. Luciani, 2019, Nature Immunology.

Intranasal vaccination with a lipopeptide containing a minimal, conserved M-protein derived peptide and a self-adjuvanting lipid induces both systemic and mucosal immune responses in mice

D. Jackson, W. Zeng, M. Batzloff, 2006 .

Chemical Synthesis of Monomeric, Dimeric and Tetrameric Forms of the Ectodomain of Influenza Matrix 2 Protein

D. Jackson, W. Zeng, Kylie J. Horrocks, 2016 .

Identification of key residues involved in fibril formation by the conserved N-terminal region of Plasmodium falciparum merozoite surface protein 2 (MSP2).

Christopher G. Adda, R. Norton, Xuecheng Zhang, 2010, Biochimie.

Chitosan-based particles as biocompatible delivery vehicles for peptide and protein-based vaccines

D. Jackson, W. Zeng, D. Mainwaring, 2012 .

Structural investigation of cysteine-rich chelating peptides by 1D- and 2D-NMR spectroscopy

W. Zeng, K. Albert, E. Bayer, 1995 .

Development of Matrix-Embedded Bovine Tracheal Organoids to Study the Innate Immune Response against Bovine Respiratory Disease

W. Zeng, G. Deliyannis, A. Diaz-Méndez, 2023, Organoids.

Tear Interferon-Gamma as a Biomarker for Evaporative Dry Eye Disease.

A. Vingrys, D. Jackson, W. Zeng, 2016, Investigative ophthalmology & visual science.

Cornea Tear Interferon-Gamma as a Biomarker for Evaporative Dry Eye Disease

A. Vingrys, D. Jackson, W. Zeng, 2016 .