T. Yoshikawa

发表

Development of amphiphilic gamma-PGA-nanoparticle based tumor vaccine: potential of the nanoparticulate cytosolic protein delivery carrier.

M. Akashi, Y. Yoshioka, S. Nakagawa, 2008, Biochemical and biophysical research communications.

Fusogenic liposome delivers encapsulated nanoparticles for cytosolic controlled gene release.

Mitsuru Akashi, Yasuo Tsutsumi, Tadanori Mayumi, 2005, Journal of controlled release : official journal of the Controlled Release Society.

Silica and titanium dioxide nanoparticles cause pregnancy complications in mice.

Yasuo Yoshioka, Yasuo Tsutsumi, Haruhiko Kamada, 2011, Nature nanotechnology.

The augmentation of intracellular delivery of peptide therapeutics by artificial protein transduction domains.

Y. Tsutsumi, S. Nakagawa, H. Kamada, 2009, Biomaterials.

Generation of mouse macrophages expressing membrane-bound TNF variants with selectivity for TNFR1 or TNFR2.

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2010, Cytokine.

Creation and X-ray Structure Analysis of the Tumor Necrosis Factor Receptor-1-selective Mutant of a Tumor Necrosis Factor-α Antagonist*

Akira Yamamoto, Yasuo Yoshioka, Takao Hayakawa, 2008, Journal of Biological Chemistry.

Simple and highly sensitive assay system for TNFR2-mediated soluble- and transmembrane-TNF activity.

Y. Yoshioka, Y. Tsutsumi, S. Nakagawa, 2008, Journal of immunological methods.

Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes

Toshiro Hirai, Yasuo Yoshioka, Yasuo Tsutsumi, 2011, Particle and Fibre Toxicology.

[Nano-safety science for assuring the safety of nanomaterials].

Y. Yoshioka, Y. Tsutsumi, T. Yoshikawa, 2010, Nihon eiseigaku zasshi. Japanese journal of hygiene.

Cutaneous exposure to agglomerates of silica nanoparticles and allergen results in IgE-biased immune response and increased sensitivity to anaphylaxis in mice

K. Ishii, Y. Yoshioka, Y. Tsutsumi, 2015, Particle and Fibre Toxicology.

Identification of new candidates as mucosal vaccine adjuvant in TNF family cytokines.

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2011, Advances in experimental medicine and biology.

Direct cell entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery.

Y. Yoshioka, S. Nakagawa, T. Yoshikawa, 2009, Biomaterials.

Distribution and histologic effects of intravenously administered amorphous nanosilica particles in the testes of mice.

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2012, Biochemical and biophysical research communications.

Intranasal exposure to amorphous nanosilica particles could activate intrinsic coagulation cascade and platelets in mice

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2013, Particle and Fibre Toxicology.

[Relation analysis between intracellular distribution of nanomateriarls, ROS generation and DNA damage].

Y. Tsutsumi, T. Yoshikawa, Tokuyuki Yoshida, 2012, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Asian Dust Particles Induce Macrophage Inflammatory Responses via Mitogen-Activated Protein Kinase Activation and Reactive Oxygen Species Production

Y. Yoshioka, Y. Tsutsumi, T. Yoshikawa, 2014, Journal of immunology research.

Novel protein engineering strategy for creating highly receptor-selective mutant TNFs.

Y. Yoshioka, Y. Tsutsumi, S. Nakagawa, 2009, Biochemical and biophysical research communications.

Limited expression of reticulocalbin-1 in lymphatic endothelial cells in lung tumor but not in normal lung.

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2011, Biochemical and biophysical research communications.

Urban aerosols induce pro-inflammatory cytokine production in macrophages and cause airway inflammation in vivo.

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2010, Biological & pharmaceutical bulletin.

Surface modification of amorphous nanosilica particles suppresses nanosilica-induced cytotoxicity, ROS generation, and DNA damage in various mammalian cells.

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2012, Biochemical and biophysical research communications.

Fine tuning of receptor-selectivity for tumor necrosis factor-α using a phage display system with one-step competitive panning.

Y. Yoshioka, Y. Tsutsumi, S. Nakagawa, 2011, Biomaterials.

Engineering of highly immunogenic long-lived DC vaccines by antiapoptotic protein gene transfer to enhance cancer vaccine potency

H. Mizuguchi, T. Yoshikawa, N. Okada, 2008, Gene Therapy.

Nanoparticles built by self-assembly of amphiphilic gamma-PGA can deliver antigens to antigen-presenting cells with high efficiency: a new tumor-vaccine carrier for eliciting effector T cells.

M. Akashi, S. Nakagawa, T. Akagi, 2008, Vaccine.

Development of tumor vaccine therapy using .GAMMA.-PGA nanoparticles as an antigen delivery carrier

S. Nakagawa, T. Yoshikawa, N. Okada, 2008 .

Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice.

Y. Yoshioka, Y. Tsutsumi, S. Nakagawa, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Extracellular phycoerythrin-like protein released by freshwater cyanobacteria Oscillatoria and Scytonema sp.

Karseno, T. Bamba, K. Harada, 2009, Biotechnology Letters.

Interleukin-1 Family Cytokines as Mucosal Vaccine Adjuvants for Induction of Protective Immunity against Influenza Virus

H. Kiyono, Y. Yoshioka, Y. Tsutsumi, 2010, Journal of Virology.

Interleukin-1 Family Cytokines as Mucosal Vaccine Adjuvants for Induction of Protective Immunity against Inﬂuenza Virus (cid:1)

H. Kiyono, Y. Yoshioka, Y. Tsutsumi, 2010 .

Fusogenic liposomes and their suitability for gene delivery

S. Nakagawa, T. Yoshikawa, N. Okada, 2006 .

Non-methylated CpG motif packaged into fusogenic liposomes enhance antigen-specific immunity in mice.

M. Akashi, Y. Tsutsumi, S. Nakagawa, 2006, Biological & pharmaceutical bulletin.

Annexin A4 is a possible biomarker for cisplatin susceptibility of malignant mesothelioma cells.

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2012, Biochemical and biophysical research communications.

TNF superfamily member, TL1A, is a potential mucosal vaccine adjuvant.

Y. Yoshioka, Y. Tsutsumi, T. Mayumi, 2009, Biochemical and biophysical research communications.

Arsenic trioxide inhibits human t cell-lymphotropic virus-1-induced syncytiums by down-regulating gp46.

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2009, Biological & pharmaceutical bulletin.

Protein corona changes mediated by surface modification of amorphous silica nanoparticles suppress acute toxicity and activation of intrinsic coagulation cascade in mice

Toshiro Hirai, Yasuo Yoshioka, Yasuo Tsutsumi, 2015, Nanotechnology.

Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application.

Y. Yoshioka, Y. Tsutsumi, S. Nakagawa, 2011, Biomaterials.

Effect of amorphous silica nanoparticles on in vitro RANKL-induced osteoclast differentiation in murine macrophages

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2011, Nanoscale research letters.

Intestinal absorption and biological effects of orally administered amorphous silica particles

Y. Yoshioka, Y. Tsutsumi, Hideki Takahashi, 2014, Nanoscale Research Letters.

Promotion of allergic immune responses by intranasally-administrated nanosilica particles in mice

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2011, Nanoscale research letters.

Effect of surface properties of silica nanoparticles on their cytotoxicity and cellular distribution in murine macrophages

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2011, Nanoscale research letters.

Liver-specific microRNAs as biomarkers of nanomaterial-induced liver damage

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2013, Nanotechnology.

Synthesis of Anti-Tumor Dimeric Indole Alkaloids in Catharanthus roseus Was Promoted by Irradiation with Near-Ultraviolet Light at Low Temperature

T. Bamba, K. Harada, T. Yoshikawa, 2010, Bioscience, biotechnology, and biochemistry.

Amorphous silica nanoparticles enhance cross-presentation in murine dendritic cells.

Y. Yoshioka, Y. Tsutsumi, Hideki Takahashi, 2012, Biochemical and biophysical research communications.

Induction of Endoplasmic Reticulum–Endosome Fusion for Antigen Cross-Presentation Induced by Poly (γ-Glutamic Acid) Nanoparticles

Y. Yoshioka, S. Nakagawa, T. Yoshikawa, 2011, The Journal of Immunology.

-Glutamic Acid) Nanoparticles g Cross-Presentation Induced by Poly ( Endosome Fusion for Antigen - Induction of Endoplasmic Reticulum

Y. Yoshioka, S. Nakagawa, T. Yoshikawa, 2011 .

[Development of intracellular drug delivery system using fusogenic liposomes].

S. Nakagawa, T. Yoshikawa, N. Okada, 2007, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

A strategy for efficient cross-presentation of CTL-epitope peptides leading to enhanced induction of in vivo tumor immunity.

Yasuo Yoshioka, Yasuo Tsutsumi, Yohei Mukai, 2007, Journal of controlled release : official journal of the Controlled Release Society.

The use of a mutant TNF-alpha as a vaccine adjuvant for the induction of mucosal immune responses.

Y. Yoshioka, Y. Tsutsumi, T. Mayumi, 2009, Biomaterials.

Development of an antibody proteomics system using a phage antibody library for efficient screening of biomarker proteins.

Y. Yoshioka, Y. Tsutsumi, S. Nakagawa, 2011, Biomaterials.

Organelle-targeted delivery of biological macromolecules using the protein transduction domain: potential applications for Peptide aptamer delivery into the nucleus.

Y. Yoshioka, Y. Tsutsumi, S. Nakagawa, 2008, Journal of molecular biology.

Preclinical Development and Validation of ASP5354: A Near-Infrared Fluorescent Agent for Intraoperative Ureter Visualization

T. Yoshikawa, H. Fushiki, A. Suwa, 2021, Molecular Imaging and Biology.

Carbon Nanotubes Elicit DNA Damage and Inflammatory Response Relative to Their Size and Shape

Yasuo Yoshioka, Yasuo Tsutsumi, Haruhiko Kamada, 2010, Inflammation.

Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure

Toshiro Hirai, Yasuo Yoshioka, Yasuo Tsutsumi, 2012, Nanotechnology.

Potential adjuvant effect of intranasal urban aerosols in mice through induction of dendritic cell maturation.

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2010, Toxicology letters.

Comparative analysis of a CFo ATP synthase subunit II homologue derived from marine and fresh-water algae.

T. Bamba, K. Harada, T. Yoshikawa, 2009, Journal of bioscience and bioengineering.

Isolation and characterization of a novel antistress gene from Chlamydomonas sp. W80.

T. Bamba, K. Harada, K. Sasaki, 2009, Journal of bioscience and bioengineering.

Vaccine efficacy of fusogenic liposomes containing tumor cell-lysate against murine B16BL6 melanoma.

Y. Tsutsumi, S. Nakagawa, T. Mayumi, 2006, Biological & pharmaceutical bulletin.

[Safety assessment of nanomaterials using toxicokinetics and toxicoproteome analysis].

Yasuo Tsutsumi, Tomoaki Yoshikawa, Hiromi Nabeshi, 2010, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Preclinical Development and Validation of ASP5354: A Near-Infrared Fluorescent Agent for Intraoperative Ureter Visualization

T. Yoshikawa, H. Fushiki, A. Suwa, 2021, Molecular Imaging and Biology.

Amorphous silica nanoparticles size-dependently aggravate atopic dermatitis-like skin lesions following an intradermal injection

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2012, Particle and Fibre Toxicology.

Carbon Nanomaterials: Efficacy and Safety for Nanomedicine

Y. Yoshioka, Y. Tsutsumi, T. Yoshikawa, 2012, Materials.

Phytochelatins inhibit the metal-induced aggregation of alpha-crystallin.

T. Bamba, K. Harada, M. Takagi, 2009, Journal of bioscience and bioengineering.

Augmentation of antigen-specific immune responses using DNA-fusogenic liposome vaccine.

M. Akashi, Y. Tsutsumi, S. Nakagawa, 2004, Biochemical and biophysical research communications.

Hazard identification of nanosilica particles using atopic dermatitis model mouse

Y. Yoshioka, Y. Tsutsumi, Hideki Takahashi, 2012 .

[Development of nanomedicine using intracellular DDS].

Y. Tsutsumi, S. Nakagawa, T. Yoshikawa, 2006, Nihon rinsho. Japanese journal of clinical medicine.

Amorphous silica nanoparticles size-dependently aggravate atopic dermatitis-like skin lesions following an intradermal injection

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2012, Particle and Fibre Toxicology.

[Evaluation of biological influence of nano-materials using toxicokinetic and toxicoproteomic approach].

Y. Yoshioka, T. Yoshikawa, H. Nabeshi, 2008, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Cutaneous exposure to agglomerates of silica nanoparticles and allergen results in IgE-biased immune response and increased sensitivity to anaphylaxis in mice

K. Ishii, Y. Yoshioka, Y. Tsutsumi, 2015, Particle and Fibre Toxicology.

Acute phase proteins as biomarkers for predicting the exposure and toxicity of nanomaterials.

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2011, Biomaterials.

Safety Evaluation Study of Nanomaterials Aimed at Promoting Their Acceptance by Society

Y. Yoshioka, Y. Tsutsumi, T. Yoshikawa, 2011 .

Acute phase proteins as biomarkers for predicting the exposure and toxicity of nanomaterials q

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2011 .

Hemopexin as biomarkers for analyzing the biological responses associated with exposure to silica nanoparticles

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2012, Nanoscale Research Letters.

Improved cytosolic translocation and tumor-killing activity of Tat-shepherdin conjugates mediated by co-treatment with Tat-fused endosome-disruptive HA2 peptide.

Y. Yoshioka, Y. Tsutsumi, S. Nakagawa, 2007, Biochemical and biophysical research communications.

Fusogenic liposome can be used as an effective vaccine carrier for peptide vaccination to induce cytotoxic T lymphocyte (CTL) response.

M. Akashi, Y. Tsutsumi, S. Nakagawa, 2005, Biological & pharmaceutical bulletin.

Evaluation of Biological Influence of Nanomaterials Using Toxicokinetic and Toxicoproteomic Approach

Y. Yoshioka, T. Yoshikawa, H. Nabeshi, 2009 .

Simple PEG conjugation of SPIO via an Au-S bond improves its tumor targeting potency as a novel MR tumor imaging agent.

M. Morita, T. Inubushi, Y. Yoshioka, 2010, Bioconjugate chemistry.

Effect of amorphous silica nanoparticles on in vitro RANKL-induced osteoclast differentiation in murine macrophages

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2011, Nanoscale research letters.

Evaluation of size-dependent acute toxicity and toxicokinetics of amorphous nanosilicas

Y. Yoshioka, Y. Tsutsumi, T. Mayumi, 2009 .

Promotion of allergic immune responses by intranasally-administrated nanosilica particles in mice

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2011 .

Size-dependent cytotoxic effects of amorphous silica nanoparticles on Langerhans cells.

Y. Yoshioka, Y. Tsutsumi, T. Imazawa, 2010, Die Pharmazie.

Effect of surface properties of silica nanoparticles on their cytotoxicity and cellular distribution in murine macrophages

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2011, Nanoscale research letters.

Direct cell entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery.

Y. Yoshioka, S. Nakagawa, T. Yoshikawa, 2009, Biomaterials.

Protein corona changes mediated by surface modification of amorphous silica nanoparticles suppress acute toxicity and activation of intrinsic coagulation cascade in mice

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2015, Nanotechnology.

Intranasal exposure to amorphous nanosilica particles could activate intrinsic coagulation cascade and platelets in mice

Y. Yoshioka, Y. Tsutsumi, H. Kamada, 2013, Particle and Fibre Toxicology.