Mizuki Takahashi

发表

Construction of a protein-detection system using a loop peptide library with a fluorescence label.

Kiyoshi Nokihara, Hisakazu Mihara, H. Mihara, 2003, Chemistry & biology.

Peptide arrays with designed α-helical structures for characterization of proteins from FRET fingerprint patterns

Kenji Usui, Kiyoshi Nokihara, Hisakazu Mihara, 2004, Molecular Diversity.

Design and discovery of new (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]piperidine-3-carboxamides as potent renin inhibitors.

Mizuki Takahashi, K. Tamaki, Y. Mori, 2012, Bioorganic & medicinal chemistry letters.

Revisiting biomolecular NMR spectroscopy for promoting small-molecule drug discovery

Mizuki Takahashi, H. Hanzawa, T. Shimada, 2020, Journal of Biomolecular NMR.

Discovery of EP300/CBP histone acetyltransferase inhibitors through scaffold hopping of 1,4-oxazepane ring.

Y. Tominaga, Mizuki Takahashi, O. Ubukata, 2022, Bioorganic & medicinal chemistry letters.

Construction of the novel conformationally-restricted peptide library for screening of peptides that control the interaction between nucleobases.

H. Mihara, Mizuki Takahashi, A. Ueno, 2002, Bioorganic & medicinal chemistry letters.

Screening of Peptides that Control Interaction Between Nucleobases from Peptide Libraries Based on Loop Structures

H. Mihara, Mizuki Takahashi, A. Ueno, 2001 .

Identification of the 5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives as highly selective PDE4B inhibitors.

Mizuki Takahashi, S. Sasaki, T. Mikkaichi, 2014, Bioorganic & medicinal chemistry letters.

Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors.

Mizuki Takahashi, S. Sasaki, Tomoko Takahashi, 2013, Bioorganic & medicinal chemistry letters.

Colletoic Acid, a Novel 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor from Colletotrichum gloeosporioides SANK 21404

Mizuki Takahashi, Yasunori Muramatsu, T. Takatsu, 2008, The Journal of Antibiotics.

Site-selective monotitanation of dialkynylpyridines and its application for preparation of highly fluorescent pi-conjugated oligomers.

Tomohiro Andou, Mizuki Takahashi, F. Sato, 2004, Organic letters.

Design and optimization of novel (2S,4S,5S)-5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxy-2-isopropylhexanamides as renin inhibitors.

Masaki Meguro, Mizuki Takahashi, K. Tamaki, 2012, Bioorganic & medicinal chemistry letters.

Discovery of DS-8108b, a Novel Orally Bioavailable Renin Inhibitor.

Mizuki Takahashi, K. Tamaki, K. Chiba, 2012, ACS medicinal chemistry letters.

Guest-responsive excimer fluorescence of β-cyclodextrin bearing a pendant group with two pyrene moieties

Mizuki Takahashi, H. Ikeda, A. Ueno, 1998 .

Preclinical Development of U3-1784, a Novel FGFR4 Antibody Against Cancer, and Avoidance of Its On-target Toxicity

P. Wirtz, R. Chapman, D. Häussinger, 2019, Molecular Cancer Therapeutics.

Crystal structure of the mineralocorticoid receptor ligand‐binding domain in complex with a potent and selective nonsteroidal blocker, esaxerenone (CS‐3150)

Mizuki Takahashi, O. Ubukata, H. Hanzawa, 2020, FEBS letters.

Revisiting biomolecular NMR spectroscopy for promoting small-molecule drug discovery

Mizuki Takahashi, H. Hanzawa, T. Shimada, 2020, Journal of Biomolecular NMR.

Peptide arrays with designed secondary structures for protein characterization using fluorescent fingerprint patterns.

Kenji Usui, Kiyoshi Nokihara, Hisakazu Mihara, 2004, Biopolymers.

A prodrug approach towards the development of tricyclic-based FBPase inhibitors.

A. Okuno, Mizuki Takahashi, K. Tamaki, 2010, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors.

Mizuki Takahashi, S. Sasaki, Tomoko Takahashi, 2013, Bioorganic & medicinal chemistry.

Discovery of potent and orally active tricyclic-based FBPase inhibitors.

A. Okuno, Mizuki Takahashi, T. Nishi, 2010, Bioorganic & medicinal chemistry.

Structure-based drug design of tricyclic 8H-indeno[1,2-d][1,3]thiazoles as potent FBPase inhibitors.

Mizuki Takahashi, T. Nishi, Takahiro Yamane, 2010, Bioorganic & medicinal chemistry letters.

Synthesis, SAR, and X-ray structure of tricyclic compounds as potent FBPase inhibitors.

Mizuki Takahashi, T. Nishi, Takahiro Yamane, 2009, Bioorganic & medicinal chemistry letters.