K. Nokihara

发表

Construction of a protein-detection system using a loop peptide library with a fluorescence label.

Kiyoshi Nokihara, Hisakazu Mihara, H. Mihara, 2003, Chemistry & biology.

Peptide arrays with designed α-helical structures for characterization of proteins from FRET fingerprint patterns

Kenji Usui, Kiyoshi Nokihara, Hisakazu Mihara, 2004, Molecular Diversity.

A novel peptide microarray for protein detection and analysis utilizing a dry peptide array system.

Takafumi Ohyama, Kenji Usui, Kiyoshi Nokihara, 2006, Molecular bioSystems.

Antioxidant Properties of Tripeptides Revealed by a Comparison of Six Different Assays

K. Nokihara, T. Ogawa, Y. Ohashi, 2015 .

Antioxidant activity of designed peptides based on the antioxidative peptide isolated from digests of a soybean protein

K. Nokihara, F. Yamauchi, K. Muramoto, 1996 .

Construction of peptide-vehicles, bioconjugates having modules for cancer cell surface capture and cell-penetrating peptide with anticancer agents

K. Nokihara, A. Hirata, 2014 .

BioShuttle Mobility in Living Cells Studied with High-Resolution FCS & CLSM Methodologies

W. Semmler, J. Debus, Marcel Beining, 2012, International journal of medical sciences.

Identification of key residues that cause differential gallbladder response to PACAP and VIP in the guinea pig.

H. Ishiguro, V. Wray, K. Nokihara, 2007, American journal of physiology. Gastrointestinal and liver physiology.

NMR spectroscopic evidence that helodermin, unlike other members of the secretin/VIP family of peptides, is substantially structured in water.

U. Lessel, D. Schomburg, W. Blankenfeldt, 1996, Biochemistry.

High throughput sequencing of cyclic peptide immobilized on a gel-type single bead

K. Nokihara, T. Ohyama, T. Kasama, 2016, Amino Acids.

Improved Synthesis Strategy for Peptide Nucleic Acids (PNA) appropriate for Cell-specific Fluorescence Imaging

Marcel Beining, R. Pipkorn, K. Nokihara, 2011, International journal of medical sciences.

MPSA short communications

W. E. Moddeman, J. A. Lindquist, D. N. Perkins, 1988 .

Structural Conversion Rate Changes of Recombinant Bovine Prion by Designed Synthetic Peptides

S. Yajima, K. Nokihara, A. Hirata, 2012, International Journal of Peptide Research and Therapeutics.

Coexistence of proguanylin (1–15) and somatostatin in the gastrointestinal tract

K. Nokihara, T. Hayakawa, S. Naruse, 1998, Journal of gastroenterology and hepatology.

Title Telomere Visualization in Tissue Sections usingPyrrole ‒ Imidazole Polyamide Probes

H. Sugiyama, M. Shimura, K. Nokihara, 2016 .

Primary structure determination of mono‐ and diacylglycerol lipase from Penicillium camembertii

K. Nokihara, K. Isobe, 1993, FEBS letters.

Novel assay with fluorescence‐labelled PrP peptides for differentiating L‐type atypical and classical BSEs, and scrapie

T. Yokoyama, S. Mohri, K. Nokihara, 2012, FEBS letters.

Angiogenic activity of osteopontin-derived peptide SVVYGLR.

M. Matsuo, M. Okazaki, N. Matsuura, 2003, Biochemical and biophysical research communications.

Osteopontin-derived peptide SVVYGLR induces angiogenesis in vivo.

M. Okazaki, N. Matsuura, T. Matsumoto, 2004, Dental materials journal.

Identification and characterization of bacterial-binding property in the type III repeat domain of fibronectin.

K. Nokihara, Hiro-o Ito, M. Inoue, 2004, Biochemical and biophysical research communications.

High throughput evaluation of the production of substituted acetylenes by the Sonogashira reaction followed by the Mizoroki–Heck reaction in ionic liquids, in situ, using a novel array reactor

T. Fukuyama, I. Ryu, K. Nokihara, 2006 .

Efficient solid-phase synthesis of a large peptide by a single coupling protocol with a single HPLC purification step

H. Nakanishi, K. Nokihara, Y. Nagawa, 1997, Letters in Peptide Science.

Peptidoglycan microarray as a novel tool to explore protein–ligand recognition

K. Fukase, K. Nokihara, A. Hirata, 2016, Biopolymers.

Characterization of Sulfhydryl Heterogeneity in Human Serum Albumin and Recombinant Human Serum Albumin for Clinical Use

K. Nokihara, K. Ikegaya, T. Yasuhara, 2010, Bioscience, biotechnology, and biochemistry.

Structural evaluation of tandem hairpin pyrrole-imidazole polyamides recognizing human telomeres.

H. Sugiyama, K. Nokihara, K. Maeshima, 2014, Journal of the American Chemical Society.

[原著］The effect of VIP and PHI-27 on oxytocin release in vitro

K. Tasaka, A. Miyake, K. Nokihara, 1985 .

PHI structural requirements for potentiation of glucose-induced insulin release

T. Fujita, K. Nokihara, N. Yanaihara, 1986, Peptides.

Immunocytochemical demonstration of PHI and its co-existence with VIP in intestinal nerves of the rat and pig.

T. Iwanaga, T. Fujita, K. Nokihara, 1983, Archivum histologicum Japonicum = Nihon soshikigaku kiroku.

Purification and characterization of a medium chain acyl-coenzyme A synthetase.

K. Nokihara, K. Igarashi, M. Fukui, 1996, Drug metabolism and disposition: the biological fate of chemicals.

The heart is the center of a new endocrine, paracrine, and neuroendocrine system.

K. Nokihara, P. Schulz-Knappe, D. Hock, 1989, Archives of histology and cytology.

Effect and distribution of intravenously injected 125I-guanylin in rat kidney examined by high-resolution light microscopic radioautography

K. Nokihara, S. Naruse, E. Ando, 1997, Anatomy and Embryology.

Telomere Visualization in Tissue Sections using Pyrrole–Imidazole Polyamide Probes

H. Sugiyama, M. Shimura, K. Nokihara, 2016, Scientific Reports.

Binding of 125I-endothelin-l to fat-storing cells in rat liver revealed by electron microscopic radioautography

K. Nokihara, S. Naruse, S. Furuya, 2004, Anatomy and Embryology.

Effect and distribution of intravenously injected 125I-endothelin-1 in rat kidney and lung examined by electron microscopic radioautography

K. Nokihara, S. Naruse, T. Nakayama, 2004, Anatomy and Embryology.

Sequence Analysis of Cysteine and Cystine Containing Peptides and Proteins by a Gas-Phase Sequencer with Isocratic Separation of PTH-Amino Acids

K. Nokihara, M. Yamaguchi, N. Morita, 1992 .

Synthesis, solution structure, binding activity, and cGMP activation of human guanylin and its disulfide isomer

V. Wray, K. Nokihara, T. Hayakawa, 1997, Regulatory Peptides.

Synthesis of human guanylin and its disulfide isomers

V. Wray, K. Nokihara, S. Naruse, 1995 .

Distribution of immunoreactive atrial and brain natriuretic peptides in the heart of the chicken, quail, snake and frog.

K. Nokihara, H. Mifune, S. Suzuki, 1996, Experimental animals.

Two-dimensional electrophoresis as a complementary method of isolating peptide fragments of cleaved proteins for internal sequencing.

K. Nokihara, N. Morita, T. Kuriki, 1994, Journal of chromatography. A.

Development of a Novel Simultaneous Multiple Separation and Synthesis Device with 96-Channel Column-like Reactors for High-throughput Library Construction

Masahiro Hattori, Kiyoshi Nokihara, Noriko Ono, 2006 .

Vasodilator effect of pituitary adenylate cyclase activating polypeptide (PACAP) on femoral blood flow in dogs

K. Nokihara, S. Naruse, T. Ozaki, 1993, Peptides.

Quantitative determination of biological sulfhydryl groups by postcolumn derivatization and elucidation of microheterogeneity of serum albumins.

K. Nokihara, T. Yasuhara, 1998, Analytical chemistry.

TWO NEW FROG SKIN PEPTIDES, PHYLLOLITORINS, OF THE BOMBESIN-RANATENSIN FAMILY FROM Phyllomedusa sauvagei

K. Nokihara, V. Erspamer, N. Yanaihara, 1983 .

Synthesis of 5-(((R,S)-5-((9-Fluorenylmethoxycarbonyl)amino)-10,11-dihydrodibenzo[a,d]cyclohepten-2-yl)oxy)valeric Acid (CHA) and 5-(((R,S)-5-((9-Fluorenylmethoxycarbonyl)amino)dibenzo[a,d]-cyclohepten-2-yl)oxy)valeric Acid (CHE) Handles for the Solid-Phase Synthesis of C-Terminal Peptide Amides und

K. Nokihara, E. Ando, M. Yamaguchi, 1994 .

Antibody specific for phosphorylated AMPA-type glutamate receptors at GluR2 Ser-696

Masao Ito, K. Nakazawa, T. Tadakuma, 1995, Neuroscience Research.

Preparative scale isolation, purification and derivatization of mimosine, a non-proteinogenic amino acid

K. Nokihara, T. Ohyama, A. Hirata, 2011, Amino Acids.

Antioxidative properties of tripeptide libraries prepared by the combinatorial chemistry.

K. Nokihara, E. Hatakeyama, T. Ogawa, 2003, Journal of agricultural and food chemistry.

Crystallization and characterization of monoacylglycerol and diacylglycerol lipase from Penicillium camembertii.

R. Schmid, K. Nokihara, S. Yamaguchi, 1992, European journal of biochemistry.

Analysis of the Hemolymph Proteins from the Acorn Barnacle Megabalanus rosa by Two-dimensional Gel Electrophoresis

H. Yako, K. Nokihara, K. Muramoto, 1996 .

Chemical Synthesis of Maxadilan, a Non-mammalian Potent Vasodilatory Peptide Consisting of 61 Amino Acids with Two Disulfide Bridges, and Its Related Peptides

V. Wray, K. Nokihara, Y. Nakata, 2007, International Journal of Peptide Research and Therapeutics.

Immunohistochemical comparison of localization of pituitary adenylate cyclase activating polypeptide (PACAP) and vasoactive intestinal polypeptide (VIP) in the enteric nerve plexus of the guinea pig jejunum.

K. Nokihara, S. Naruse, E. Ando, 1996, Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity.

Immunochemical study on PHI/PHM with use of synthetic peptides

S. Fukata, K. Nokihara, N. Yanaihara, 1984, Peptides.

A naturally occurring single basic amino acid substitution in the V3 region of the human immunodeficiency virus type 1 env protein alters the cellular host range and antigenic structure of the virus

S. Oka, Y. Takebe, Y. Nagai, 1994, Journal of virology.

Identification and characterization of HLA-B*5401-restricted HIV-1-Nef and Pol-specific CTL epitopes.

S. Oka, K. Nokihara, T. Akahoshi, 2008, Microbes and infection.

HLA-B*3501-peptide interactions: role of anchor residues of peptides in their binding to HLA-B*3501 molecules.

S Ferrone, K Kano, C. Schönbach, 1994, International immunology.

Screening of Peptides that Inhibit Bacterial Binding to Fibronectin using Combinatorial Peptide Libraries

K. Nokihara, T. Ohyama, Hiro-o Ito, 2006, International Journal of Peptide Research and Therapeutics.

Refined peptide HLA-B*3501 binding motif reveals differences in 9-mer to 11-mer peptide binding

Kiyoshi Miwa, Masafumi Takiguchi, Kiyoshi Nokihara, 1996, Immunogenetics.

Residue 116 determines the C-terminal anchor residue of HLA-B*3501 and -B*5101 binding peptides but does not explain the general affinity difference

Kiyoshi Miwa, Christian Schönbach, Kiyoshi Nokihara, 1998, Immunogenetics.

Indication of possible post-translational formation of disulphide bonds in the beta-sheet domain of human lysozyme.

E. Kanaya, M. Kikuchi, K. Nokihara, 1993, The Biochemical journal.

Procedures leading to primary structure determination of proteins in complex mixtures by gel electrophoresis and modern micro-scale analyses

K. Nokihara, 1998 .

Fine tuning of peptide binding to HLA-B*3501 molecules by nonanchor residues.

C. Schönbach, K. Nokihara, K. Miwa, 1995, Journal of immunology.

Further characterization of anchor and non-anchor residues on deca- and undeca-peptides in addition to nona-peptides, which bind to the HLA Class I molecules (HLA-B*3501)

C. Schönbach, K. Nokihara, M. Takiguchi, 2002 .

Crucial role of N-terminal residue of binding peptides in recognition of the monoclonal antibody specific for the peptide-HLA-B5, -B35 complex

C. Schönbach, M. Edidin, K. Nokihara, 1997, Immunogenetics.

Characterization of peptides obtained from digests of bovine brain which accelerate structural conversions of the recombinant bovine prion protein

S. Yajima, K. Nokihara, Tetsuya Sogon, 2013, FEBS letters.

SEPARATION OF PEPTIDES HAVING STRUCTURES AND DERIVATIVES OF MIMOSINE, A NONPROTEINOGENIC AMINO ACID, BY A NOVEL REVERSE-PHASE HPLC COLUMN PACKED WITH WIDE-PORE SILICA

K. Nokihara, A. Hirata, M. Miyajima, 2013 .

Structural Conversion Rate Changes of Recombinant Bovine Prion by Designed Synthetic Peptides

S. Yajima, K. Nokihara, A. Hirata, 2012, International Journal of Peptide Research and Therapeutics.

Improved Primary Structure Determination for Peptides and Proteins by Electroblotting in Combination with Sequencing

K. Nokihara, R. Beck, F. Herbst, 1988 .

Development of an improved automated gas-chromatographic chiral analysis system: application to non-natural amino acids and natural protein hydrolysates.

K. Nokihara, J. Gerhardt, 2001, Chirality.

Gas-phase microsequencing of peptides and proteins with a fluorescent Edman-type reagent, fluorescein isothiocyanate.

K. Nokihara, K. Muramoto, H. Kamiya, 1994, Bioscience, biotechnology, and biochemistry.

Applications of a novel biodetection system to saliva using protein fingerprints with data processing.

K. Nokihara, K. Usui, A. Hirata, 2018, Bioorganic & medicinal chemistry.

Photo‐Modification of Melanin by a Mid‐infrared Free‐electron Laser

K. Nokihara, K. Tsukiyama, T. Oyama, 2019, Photochemistry and photobiology.

Synthesis of PHI (peptide histidine isoleucine) and related peptides and immunochemical confirmation of amino acid residue in position 24 of PHI with use of the synthetic peptides

V. Mutt, S. Fukata, K. Nokihara, 1984 .

Immunocytochemical evidence for CDD/ANP-like peptides in strands of myoendocrine cells associated with the ventricular conduction system of the rat heart

K. Nokihara, E. Ando, H. Back, 2004, Anatomy and Embryology.

Solution structure of pituitary adenylate cyclase activating polypeptide by nuclear magnetic resonance spectroscopy.

V. Wray, K. Nokihara, S. Naruse, 1993, Biochemistry.

Complete determination of disulfide forms of purified recombinant human serum albumin, secreted by the yeast Pichia pastoris.

M. Hirose, T. Ohmura, K. Nokihara, 1997, Analytical chemistry.

Effects of PACAP‐VIP Hybrid Peptides on Gastric Blood Flow in Conscious Dogs a

V. Wray, K. Nokihara, T. Hayakawa, 1996, Annals of the New York Academy of Sciences.

Possible key residues that determine left gastric artery blood flow response to PACAP in dogs.

V. Wray, K. Nokihara, Ping Wang, 2010, World journal of gastroenterology.

Identification of HTLV-1-specific CTL directed against synthetic and naturally processed peptides in HLA-B*3501 transgenic mice.

C. Schönbach, K. Takatsu, K. Nokihara, 1996, Virology.

Solution Structure Comparison of the VIP/PACAP Family of Peptides by NMR Spectroscopy

V. Wray, K. Nokihara, S. Naruse, 1998, Annals of the New York Academy of Sciences.

Recognition of a monoclonal antibody against a small molecular weight antigen by monitoring the antigen-antibody reaction using fluorescence labeled structured peptides.

K. Nokihara, A. Hirata, Yuki Tominaga, 2015, Bioorganic & medicinal chemistry letters.

Peptide arrays with designed secondary structures for protein characterization using fluorescent fingerprint patterns.

Kenji Usui, Kiyoshi Nokihara, Hisakazu Mihara, 2004, Biopolymers.

High-throughput analysis of total nitrogen content that replaces the classic Kjeldahl method.

K. Nokihara, T. Yasuhara, 2001, Journal of Agricultural and Food Chemistry.

Antioxidative Properties of Histidine-Containing Peptides Designed from Peptide Fragments Found in the Digests of a Soybean Protein.

K. Nokihara, F. Yamauchi, Chen, 1998, Journal of agricultural and food chemistry.

Differences in Action of PACAP-27 and PACAP-38 on Guinea Pig Gallbladder Smooth Muscle Using Synthetic C-terminally Modified PACAP Peptides

V. Wray, K. Nokihara, S. Naruse, 2009, International Journal of Peptide Research and Therapeutics.

Structural Requirements of Maxadilan, a Non-Mammalian Potent Vasodilatory Peptide, for Interaction with the PAC-1 Receptor from Rat Brain Using a Synthetic Mini-Library

V. Wray, K. Nokihara, Y. Nakata, 2008, International Journal of Peptide Research and Therapeutics.

The effect of pituitary adenylate cyclase activating polypeptide (PACAP) on amylase secretion from guinea pig pancreatic acini.

H. Ishiguro, K. Nokihara, T. Hayakawa, 1995, Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity.

Synthesis, solution structure and biological action of PACAP-related peptide.

V. Wray, K. Nokihara, S. Naruse, 1995, Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity.

Development of pituitary adenylate cyclase activating polypeptides (PACAPs) specific radioimmunoassay systems and distribution of PACAP-like immunoreactivity in guinea pig tissues.

K. Nokihara, S. Naruse, E. Ando, 1994, Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity.

Characterization of peptides obtained from digests of bovine brain which accelerate structural conversions of the recombinant bovine prion protein

S. Yajima, K. Nokihara, Tetsuya Sogon, 2013, FEBS letters.

Matrix-assisted ultraviolet laser desorption/ionization mass spectrometry applied to multiple forms of lipases.

M. Karas, F. Hillenkamp, F. Spener, 1993, Analytical biochemistry.

Fingerprint-Detection of Sugar-Binding Proteins Generated by Labeled Structured Glycopeptides Arrays

K. Nokihara, T. Ohyama, A. Hirata, 2010 .

Highly efficient peptide-amide preparation using a simultaneous multiple-peptide synthesizer with two novel acid labile linkers

K. Nokihara, E. Ando, M. Yamaguchi, 1994 .