J. Fehrentz

发表

A. Moulin, Jean Martinez, J. Fehrentz, 2007, Journal of peptide science : an official publication of the European Peptide Society.

In Vivo Stabilization of a Gastrin-Releasing Peptide Receptor Antagonist Enhances PET Imaging and Radionuclide Therapy of Prostate Cancer in Preclinical Studies

D. V. van Gent, M. de Jong, Jean Martinez, 2016, Theranostics.

Differential Effects of a Full and Biased Ghrelin Receptor Agonist in a Mouse Kindling Model

J. Fehrentz, I. Smolders, D. De Bundel, 2019, International journal of molecular sciences.

Post‐synthesis incorporation of a lipidic side chain into a peptide on solid support

A. Heitz, Jean Martinez, J. Fehrentz, 2002, Journal of peptide science : an official publication of the European Peptide Society.

Synthesis of N- and side chain protected aspartyl and glutamyl aldehyde derivatives. Reinvestigation of the reduction of Weinreb amides

A. Heitz, Jean Martinez, J. Fehrentz, 1998 .

Evidence for a Direct Interaction between the Penultimate Aspartic Acid of Cholecystokinin and Histidine 207, Located in the Second Extracellular Loop of the Cholecystokinin B Receptor*

B. Maigret, N. Vaysse, S. Silvente-Poirot, 1999, The Journal of Biological Chemistry.

Heterodimerization with Its Splice Variant Blocks the Ghrelin Receptor 1a in a Non-signaling Conformation

B. Mouillac, Jean Martinez, J. Fehrentz, 2013, The Journal of Biological Chemistry.

Pharmacological and Biochemical Characterization of TLQP-21 Activation of a Binding Site on CHO Cells

G. Biagini, R. J. Omeljaniuk, V. Locatelli, 2017, Front. Pharmacol..

A Go‐like protein in Drosophila melanogaster and its expression in memory mutants.

J. Bockaert, J. Fehrentz, J. Jallon, 1990, The EMBO journal.

Use of coated capillaries for the electrophoretic separation of stereoisomers of a growth hormone secretagogue

C. Perrin, Jean Martinez, J. Fehrentz, 2009, Electrophoresis.

Growth hormone secretagogues hexarelin and JMV2894 protect skeletal muscle from mitochondrial damages in a rat model of cisplatin-induced cachexia

A. Torsello, E. Conte, L. Rizzi, 2017, Scientific Reports.

Solution synthesis of antigenic and inhibiting peptides of the human renin prosegment-2. [Tyr40] preprorenin-(40-50) peptide methyl ester.

R. Seyer, A. Heitz, J. Fehrentz, 1986, International journal of peptide and protein research.

Solution synthesis of antigenic and inhibiting peptides of the human renin prosegment-1. [Tyr47, Nle53] preprorenin-(47-60) peptide methyl ester.

R. Seyer, A. Heitz, J. Fehrentz, 1986, International journal of peptide and protein research.

Inhibition of human renin by synthetic peptides derived from its prosegment.

J. Ménard, G. Evin, R. Seyer, 1985, The Journal of biological chemistry.

Progressive Seizure Aggravation in the Repeated 6-Hz Corneal Stimulation Model Is Accompanied by Marked Increase in Hippocampal p-ERK1/2 Immunoreactivity in Neurons

G. Leo, G. Biagini, A. Torsello, 2016, Front. Cell. Neurosci..

Immunologic identification of both plasma and human renal inactive renin as prorenin.

J. Ménard, G. Evin, R. Seyer, 1985, The Journal of clinical endocrinology and metabolism.

PLASMA LEVELS OF GHRELIN, DES-ACYL GHRELIN AND LEAP2 IN CHILDREN WITH OBESITY: CORRELATION WITH AGE AND INSULIN RESISTANCE.

J. Fehrentz, M. Perelló, M. Fasano, 2019, European journal of endocrinology.

Structure of cholecystokinin receptor binding sites and mechanism of activation/inactivation by agonists/antagonists.

B. Maigret, L. Pradayrol, S. Silvente-Poirot, 2002, Pharmacology & toxicology.

Arginine 197 of the cholecystokinin‐A receptor binding site interacts with the sulfate of the peptide agonist cholecystokinin

B. Maigret, N. Vaysse, S. Silvente-Poirot, 2008, Protein science : a publication of the Protein Society.

Arginine 336 and Asparagine 333 of the Human Cholecystokinin-A Receptor Binding Site Interact with the Penultimate Aspartic Acid and the C-terminal Amide of Cholecystokinin*

B. Maigret, N. Vaysse, Jean Martinez, 1999, The Journal of Biological Chemistry.

Recent Developments in Ghrelin Receptor Ligands

A. Moulin, Jean Martinez, J. Fehrentz, 2007, ChemMedChem.

Synthesis of Various Chiral 1,2,4-Triazole-Containing α-Amino Acids from Aspartic or Glutamic Acids

A. Blayo, Jean Martinez, J. Fehrentz, 2011 .

Multi-gram scale mercury-free synthesis of optically pure 3,4,5-trisubstituted 1,2,4-triazoles using silver benzoate

A. Blayo, A. Moulin, Jean Martinez, 2010 .

Solution and solid-supported synthesis of 3,4,5-trisubstituted 1,2,4-triazole-based peptidomimetics.

S. Cantel, Jean Martínez, A. Heitz, 2003, Organic letters.

Synthesis of 3,4,5-trisubstituted-1,2,4-triazoles.

A. Blayo, A. Moulin, Jean Martinez, 2010, Chemical reviews.

STIM Proteins and Orai Ca2+ Channels Are Involved in the Intracellular Pathways Activated by TLQP-21 in RAW264.7 Macrophages

G. Biagini, R. J. Omeljaniuk, V. Locatelli, 2018, Front. Pharmacol..

The epimerization of peptide aldehydes—a systematic study

A. Moulin, Jean Martinez, J. Fehrentz, 2006, Journal of peptide science : an official publication of the European Peptide Society.

Solid phase synthesis of peptide aldehydes

A. Heitz, Jean Martinez, J. Fehrentz, 2002 .

Synthesis of peptide aldehydes on solid support

A. Heitz, Jean Martinez, J. Fehrentz, 1999 .

Synthesis of peptide aldehydes on solid support using ozonolysis

A. Heitz, Jean Martinez, J. Fehrentz, 1998 .

Improved solid phase synthesis of C-terminal peptide aldehydes

A. Heitz, Jean Martinez, J. Fehrentz, 1995 .

Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin‐induced cachexia

A. Torsello, E. Conte, E. Bresciani, 2017, Journal of cachexia, sarcopenia and muscle.

Direct, simplified, and sensitive assay of angiotensin II in plasma extracts performed with a high-affinity monoclonal antibody.

B. Pau, P. Corvol, J. Fehrentz, 1992, Clinical chemistry.

Analysis of inactive renin by renin profragment monoclonal antibodies

B. Pau, R. Seyer, P. Corvol, 1986, FEBS letters.

GHSR controls food deprivation-induced activation of CRF neurons of the hypothalamic paraventricular nucleus in a LEAP2-dependent manner

S. Cantel, H. Schiöth, A. Giovambattista, 2022, Cellular and Molecular Life Sciences.

From JMV-1843 to Macrilen

Jean Martinez, J. Fehrentz, 2020 .

The 1,2,4-triazole as a scaffold for the design of ghrelin receptor ligands: development of JMV 2959, a potent antagonist

A. Moulin, Jean Martinez, J. Fehrentz, 2012, Amino Acids.

EP1572: A novel peptido-mimetic GH secretagogue with potent and selective GH-releasing activity in man

E. Arvat, E. Ghigo, V. Locatelli, 2002, Journal of endocrinological investigation.

Production and characterization of human renin antibodies with region-oriented synthetic peptides.

J. Ménard, R. Seyer, J. Fehrentz, 1987, The Journal of biological chemistry.

Synthesis, conformation, and antibody recognition of peptides built of the sequence of the flap of human renin

F. Heitz, A. Heitz, J. Fehrentz, 1988 .

Regulation of ERK1/2 activity by ghrelin‐activated growth hormone secretagogue receptor 1A involves a PLC/PKCɛ pathway

Jean Martinez, J. Fehrentz, C. Oiry, 2006 .

High Constitutive Activity Is an Intrinsic Feature of Ghrelin Receptor Protein

Jean Martinez, J. Fehrentz, J. Banères, 2011, The Journal of Biological Chemistry.

Conformation of the flap of human renin

P. Corvol, F. Heitz, A. Heitz, 1988 .

JMV641: A potent bombesin receptor antagonist that inhibits Swiss 3T3 cell proliferation

J. Fehrentz, M. Llinares, J. Azay, 1996, Regulatory Peptides.

Syntheses and biological activities of potent bombesin receptor antagonists.

J. Fehrentz, O. Chaloin, M. Llinares, 1999, The journal of peptide research : official journal of the American Peptide Society.

JMV5656, a short synthetic derivative of TLQP-21, alleviates acid-induced lung injury and fibrosis in mice.

R. J. Omeljaniuk, A. Torsello, E. Bresciani, 2020, Pulmonary pharmacology & therapeutics.

Peptide-poly(L-lysine citramide) conjugates and their in vitro anti-HIV behavior.

Michel Vert, M. Vert, Jean Martinez, 2009, Biomacromolecules.

Synthesis and Antibacterial Activity of tert‐Butyl [1‐benzyl‐2[(4‐aryl‐2‐thiazolyl)hydrazono]ethyl]carbamate Derivatives

Jean Martinez, J. Fehrentz, G. Turan‐Zitouni, 2007, Archiv der Pharmazie.

Attenuation of cocaine‐induced locomotor sensitization in rats sustaining genetic or pharmacologic antagonism of ghrelin receptors

Jean Martinez, J. Fehrentz, P. Wellman, 2012, Addiction biology.

Structure and dynamics of receptor-bound neuropeptides

R. Stevens, V. Cherezov, A. Milon, 2018 .

Ghrelin agonists impact on Fos protein expression in brain areas related to food intake regulation in male C57BL/6 mice

J. Fehrentz, J. Bundzikova, A. Kiss, 2011, Neurochemistry International.

New trisubstituted 1,2,4-triazole derivatives as potent ghrelin receptor antagonists. 3. Synthesis and pharmacological in vitro and in vivo evaluations.

V. Locatelli, A. Torsello, A. Moulin, 2008, Journal of medicinal chemistry.

Trisubstituted 1,2,4-triazoles as ligands for the ghrelin receptor: on the significance of the orientation and substitution at position 3.

A. Moulin, Jean Martinez, J. Fehrentz, 2008, Bioorganic & medicinal chemistry letters.

Toward potent ghrelin receptor ligands based on trisubstituted 1,2,4-triazole structure. 2. Synthesis and pharmacological in vitro and in vivo evaluations.

V. Locatelli, A. Torsello, A. Heitz, 2007, Journal of medicinal chemistry.

Synthesis and pharmacological in vitro and in vivo evaluations of novel triazole derivatives as ligands of the ghrelin receptor. 1.

V. Locatelli, A. Torsello, A. Heitz, 2007, Journal of medicinal chemistry.

Heterodimerization with its splice variant blocks the ghrelin receptor 1a in a nonsignaling conformation. A study with a purified heterodimer assembled into lipid discs.*

B. Mouillac, Jean Martinez, J. Fehrentz, 2013 .

Immunological approach to blockade of the renin-substrate reaction

J. Michel, P. Corvol, J. Fehrentz, 1989, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.

A Novel Truncated Liver Enriched Antimicrobial Peptide-2 Palmitoylated at its N-Terminal Antagonizes Effects of Ghrelin

S. Cantel, J. Fehrentz, S. Denoyelle, 2022, The Journal of Pharmacology and Experimental Therapeutics.

A novel truncated LEAP2 palmitoylated at its N-terminal antagonizes effects of ghrelin

S. Cantel, J. Fehrentz, S. Denoyelle, 2022 .

Solid phase synthesis of chiral 3-substituted quinazoline-2,4-diones

Jean Martínez, J. Fehrentz, F. Winternitz, 1996 .

Functionalization of peptides and proteins by aldehyde or keto groups.

J. Fehrentz, H. Gras-masse, J. Martinez, 2001, Biopolymers.

The GHR-R antagonist JMV 2959 neither induces malaise nor alters the malaise property of LiCl in the adult male rat

Jean Martinez, J. Fehrentz, P. Wellman, 2018, Physiology & Behavior.

Ghrelin knockout mice show decreased voluntary alcohol consumption and reduced ethanol-induced conditioned place preference

Jean Martinez, J. Fehrentz, C. Tomasetto, 2013, Peptides.

Ghrelin agonist JMV 1843 increases food intake, body weight and expression of orexigenic neuropeptides in mice.

J. Fehrentz, Z. Demianová, M. Haluzík, 2013, Physiological research.

Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling*

Jean Martinez, J. Fehrentz, S. Denoyelle, 2015, The Journal of Biological Chemistry.

Design and Characterization of a Triazole-Based Growth Hormone Secretagogue Receptor Modulator Inhibiting the Glucoregulatory and Feeding Actions of Ghrelin.

S. Cantel, J. Fehrentz, S. Denoyelle, 2022, Biochemical pharmacology.

Gastrin releasing peptide receptor-directed radioligands based on a bombesin antagonist: synthesis, (111)in-labeling, and preclinical profile.

E. Krenning, M. de Jong, Jean Martinez, 2013, Journal of medicinal chemistry.

N-Terminal Liver-Expressed Antimicrobial Peptide 2 (LEAP2) Region Exhibits Inverse Agonist Activity toward the Ghrelin Receptor.

S. Cantel, J. Fehrentz, S. Denoyelle, 2018, Journal of medicinal chemistry.

Utrophin Localization in Normal and Dystrophin‐Deficient Heart

E. Fabbrizio, Jean Martinez, J. Fehrentz, 1994, Circulation.

An efficient synthesis of optically active α-(t-butoxycarbonylamino)-aldehydes from α-amino acids

J. Fehrentz, B. Castro, 1983 .

Aldehydic peptides inhibiting renin

A. Heitz, J. Fehrentz, D. Nisato, 1984, FEBS letters.

Anorexigenic and electrophysiological actions of novel ghrelin receptor (GHS-R1A) antagonists in rats.

A. Moulin, Jean Martinez, J. Fehrentz, 2009, European journal of pharmacology.

Regulation of ERK1/2 activity by ghrelin-activated growth hormone secretagogue receptor 1A involves a PLC/PKCvarepsilon pathway.

Jean Martinez, J. Fehrentz, C. Oiry, 2006, British journal of pharmacology.

TLQP-21 modulate inflammation and fibrosis in a model of ards

A. Pesenti, A. Torsello, L. Rizzi, 2015, Intensive Care Medicine Experimental.

Ghrelin proteolysis increases in plasma of men, but not women, with obesity.

S. Cantel, J. Fehrentz, L. Luyt, 2022, Life sciences.

New ligands of the ghrelin receptor based on the 1,2,4-triazole scaffold by introduction of a second chiral center.

A. Blayo, Jean Martinez, J. Fehrentz, 2016, Bioorganic & medicinal chemistry letters.

Synthesis of N-protected α-amino aldehydes from their morpholine amide derivatives

Jean Martínez, A. Heitz, J. Fehrentz, 2000 .

Synthesis and biological activities of peptidomimetic analogues of compound A71623, a potent and selective CCK-A receptor agonist

Jean Martinez, J. Fehrentz, M. Amblard, 1997, Letters in Peptide Science.

Synthesis of chiral N-protected β-amino alcohols by the use of UNCAs

Jean Martinez, J. Fehrentz, M. Amblard, 1994 .

An Efficient Synthesis of Optically Active α-(t-Butoxycarbonylamino)-aldehydes from α-Amino Acids

J. Fehrentz, B. Castro, 1983 .

Synthesis of N-protected γ-amino-β-keto-esters from urethane N-carboxyanhydrides (UNCAs)

A. Heitz, Jean Martinez, J. Fehrentz, 1996 .

Fundamentals of modern peptide synthesis.

Jean Martínez, J. Fehrentz, M. Amblard, 2006, Methods in molecular biology.

Convenient two-step preparation of [1,2,4]triazolo[4,3-a]pyridines from 2-hydrazinopyridine and carboxylic acids

A. Moulin, Jean Martinez, J. Fehrentz, 2006 .

Preparation of Some Thiazolyl Hydrazone Derivatives and Evaluation of Their Antibacterial Activities

Jean Martinez, J. Fehrentz, Z. Kaplancıklı, 2009 .

Amino acids as building blocks for the synthesis of substituted 1,2,4-triazoles

Jean Martínez, J. Fehrentz, Mathieu Bibian, 2011 .

The use of N‐urethane‐protected N‐carboxyanhydrides (UNCAs) in amino acid and peptide synthesis

Jean Martinez, J. Fehrentz, M. Amblard, 1995, Journal of peptide science : an official publication of the European Peptide Society.

Synthesis of aldehydic peptides inhibiting renin.

A. Heitz, J. Fehrentz, B. Castro, 2009, International journal of peptide and protein research.

Some of the amino acid chemistry going on in the Laboratory of Amino Acids, Peptides and Proteins

C. Enjalbal, J. Lavergne, J. Fehrentz, 2005, Amino Acids.

Some of the amino acid chemistry going on in the Laboratory of Amino Acids, Peptides and Proteins Review Article

C. Enjalbal, J. Lavergne, J. Fehrentz, 1999 .

Efficient solid-phase synthesis of 4,5-dihydro-1,2,4-triazin-6(1H)-ones

S. Cantel, Jean Martínez, J. Fehrentz, 2003 .

Reactivity of UNCAs with Grignard reagents

Jean Martinez, J. Fehrentz, Catherine Pothion, 1997, Letters in Peptide Science.

N-urethane protected carboxyanhydrides (UNCAs) in amino acid and peptide chemistry

J. Fehrentz, J. Martínez, M. Paris, 2002 .

New hydroxamate inhibitors of neurotensin-degrading enzymes. Synthesis and enzyme active-site recognition.

J. Fehrentz, P. Kitabgi, J. Martinez, 2009, International journal of peptide and protein research.

Methods and protocols of modern solid phase peptide synthesis

Jean Martínez, J. Fehrentz, M. Amblard, 2006, Molecular biotechnology.

Synthesis of chiral urethane N-alkoxycarbonyl tetramic acids from urethane N-carboxyanhydrides (UNCAs)

Jean Martinez, J. Fehrentz, O. Chaloin, 1994 .

HIV-1 protease inhibitors containing statine: inhibitory potency and antiviral activity.

J. Chermann, J. Fehrentz, D. Nisato, 1992, Biochemical and biophysical research communications.

Statine based tripeptides as potent inhibitors of HIV-1 replication.

J. Chermann, J. Fehrentz, D. Nisato, 1992, Biochemical and biophysical research communications.

Solution and solid-supported synthesis of 3,4,5-trisubstituted 1,2,4-triazole-based peptidomimetics.

S. Cantel, Jean Martínez, A. Heitz, 2003, Organic letters.

Antidiabetic potential of two medicinal plants used in Gabonese folk medicine

Marcel Garcia, J. Fehrentz, T. Cresteil, 2016, BMC Complementary and Alternative Medicine.

GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation

H. Hamm, G. Ferry, J. Boutin, 2018, Proceedings of the National Academy of Sciences.

Enantioselective Synthesis of N-Protected α-Amino Acid Hydrazides

Jean Martinez, J. Fehrentz, Mathieu Bibian, 2009 .

A C-terminal aldehyde analog of the insect kinins inhibits diuresis in the housefly

Jean Martinez, J. Fehrentz, J. Zabrocki, 2007, Peptides.

Synthesis of peptide aldehydes

A. Moulin, Jean Martinez, J. Fehrentz, 2007, Journal of peptide science : an official publication of the European Peptide Society.

Stereoselective synthesis of allyl- and homoallylglycines

Jean Martínez, A. Heitz, J. Fehrentz, 2001 .

JMV5656, A Novel Derivative of TLQP-21, Triggers the Activation of a Calcium-Dependent Potassium Outward Current in Microglial Cells

R. J. Omeljaniuk, V. Locatelli, A. Torsello, 2017, Front. Cell. Neurosci..

In Vitro and In Vivo Application of Radiolabeled Gastrin-Releasing Peptide Receptor Ligands in Breast Cancer

Marion de Jong, Erik de Blois, Luc Brunel, 2015, The Journal of Nuclear Medicine.

Synthesis and pharmacological evaluation of a new series of bombesin analogs

Jean Martinez, J. Fehrentz, J. Pannequin, 2002 .

A synthetic glycine-extended bombesin analogue interacts with the GRP/bombesin receptor.

J. Fehrentz, J. Pannequin, C. Oiry, 2000, European journal of pharmacology.

Study of the Tissue Distribution of TLQP-21 in Mice Using [18F]JMV5763, a Radiolabeled Analog Prepared via [18F]Aluminum Fluoride Chelation Chemistry

P. Rainone, A. Torsello, E. Bresciani, 2018, Front. Pharmacol..

Biophysical characterization of a binding site for TLQP-21, a naturally occurring peptide which induces resistance to obesity.

R. J. Omeljaniuk, V. Locatelli, A. Torsello, 2013, Biochimica et biophysica acta.

Use of ozonolysis in the synthesis of C-terminal peptide aldehydes on solid support

L. Rocheblave, A. Heitz, Jean Martinez, 1997 .

ZZ domain of dystrophin and utrophin: topology and mapping of a beta-dystroglycan interaction site.

S. Winder, S. Cantel, J. Bramham, 2007, The Biochemical journal.

Allosteric modulation of ghrelin receptor signaling by lipids

P. Bisch, S. Cantel, L. Catoire, 2021, Nature Communications.

Dystrophin and Utrophin Complexed with Different Associated Proteins in Cardiac Purkinje Fibres

F. Rivier, Jean Martinez, J. Fehrentz, 1999, The Histochemical Journal.

Formation of multiple complexes between beta-dystroglycan and dystrophin family products

F. Rivier, R. Paniagua, M. Royuela, 2004, Journal of Muscle Research & Cell Motility.

New active series of growth hormone secretagogues.

V. Locatelli, A. Torsello, A. Heitz, 2003, Journal of Medicinal Chemistry.

Involvement of PKA and ERK pathways in ghrelin‐induced long‐lasting potentiation of excitatory synaptic transmission in the CA1 area of rat hippocampus

J. Guiramand, M. Vignes, M. Cavalier, 2015, The European journal of neuroscience.

Biotinylated non-ionic amphipols for GPCR Ligands Screening.

G. Durand, J. Fehrentz, A. Polidori, 2020, Methods.

Anticonvulsant effect of a ghrelin receptor agonist in 6Hz corneally kindled mice

Jean Martinez, J. Fehrentz, I. Smolders, 2016, Epilepsia.

New trisubstituted 1,2,4-triazoles as ghrelin receptor antagonists.

A. Blayo, Jean Martinez, J. Fehrentz, 2015, Bioorganic & medicinal chemistry letters.

Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor

Jean Martinez, J. Fehrentz, J. Banères, 2012, Proceedings of the National Academy of Sciences.

Homogeneous time-resolved fluorescence-based assay to screen for ligands targeting the growth hormone secretagogue receptor type 1a.

T. Roux, Emmanuel Bourrier, L. Lamarque, 2011, Analytical biochemistry.

Ghrelin Stimulation of Growth Hormone-Releasing Hormone Neurons Is Direct in the Arcuate Nucleus

I. Robinson, Jean Martinez, J. Fehrentz, 2010, PloS one.

Activation of the ghrelin receptor is described by a privileged collective motion: a model for constitutive and agonist-induced activation of a sub-class A G-protein coupled receptor (GPCR).

David Perahia, Nicolas Floquet, D. Pérahia, 2010, Journal of molecular biology.

Syntheses and biological activities of bombesin analogs modified in the C-terminal dipeptide part

J. Fehrentz, M. Llinares, Jean Martinez, 1997 .

JMV2894, a novel growth hormone secretagogue, accelerates body mass recovery in an experimental model of cachexia

G. Biagini, R. J. Omeljaniuk, V. Locatelli, 2017, Endocrine.

Preclinical Comparison of Al18F- and 68Ga-Labeled Gastrin-Releasing Peptide Receptor Antagonists for PET Imaging of Prostate Cancer

W. Mcbride, O. Boerman, M. de Jong, 2014, The Journal of Nuclear Medicine.

Met-195 of the Cholecystokinin-A Receptor Interacts with the Sulfated Tyrosine of Cholecystokinin and Is Crucial for Receptor Transition to High Affinity State*

B. Maigret, N. Vaysse, S. Silvente-Poirot, 1998, The Journal of Biological Chemistry.

Variations in Dystrophin Complex in Red and White Caudal Muscles from Torpedo marmorata

F. Rivier, R. Paniagua, M. Royuela, 2001, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Dystrophin and dystrophin-associated protein in muscles and nerves from monkey.

F. Rivier, R. Paniagua, M. Royuela, 2009, European journal of histochemistry : EJH.

Urethane N-Carboxyanhydrides from β-Amino Acids.

Jean Martínez, J. Fehrentz, M. Mckiernan, 2002 .

Melanin-concentrating hormone binding sites in human SVK14 keratinocytes.

Jean Martinez, J. Fehrentz, J. Nahon, 1997, Biochemical and biophysical research communications.

Detergent-free Isolation of Functional G Protein-Coupled Receptors into Nanometric Lipid Particles.

O. Nosjean, G. Ferry, J. Boutin, 2016, Biochemistry.

The 1,2,4-triazole as a scaffold for the design of ghrelin receptor ligands: development of JMV 2959, a potent antagonist

A. Moulin, Jean Martinez, J. Fehrentz, 2013, Amino Acids.

Involvement of PPARγ in the Anticonvulsant Activity of EP-80317, a Ghrelin Receptor Antagonist

G. Leo, G. Biagini, A. Torsello, 2017, Front. Pharmacol..

Systemic Ghrelin Treatment Induces Rapid, Transient, and Asymmetric Changes in the Metabolic Activity of the Mouse Brain

J. Fehrentz, M. Perelló, G. Falasco, 2022, Neuroendocrinology.

Growth hormone secretagogue receptor signaling in the supramammillary nucleus targets nitric oxide-producing neurons and controls recognition memory in mice

J. Zigman, J. Fehrentz, M. Perelló, 2022, Psychoneuroendocrinology.

Circulating ghrelin crosses the blood-cerebrospinal fluid barrier via growth hormone secretagogue receptor dependent and independent mechanisms

S. Cantel, J. Fehrentz, V. Prévot, 2021, Molecular and Cellular Endocrinology.

Development of a novel fluorescent ligand of growth hormone secretagogue receptor based on the N-Terminal Leap2 region

S. Cantel, J. Fehrentz, S. Denoyelle, 2019, Molecular and Cellular Endocrinology.

Rapid sensing of circulating ghrelin by hypothalamic appetite-modifying neurons

T. Roux, Emmanuel Bourrier, L. Lamarque, 2013, Proceedings of the National Academy of Sciences.

Synthesis of 2,6‐Disubstituted Piperidine‐Bearing α‐Amino Acid Side‐Chains

Jean Martínez, A. Heitz, J. Fehrentz, 2003 .

Imaging heterogeneity of peptide delivery and binding in solid tumors using SPECT imaging and MRI

M. de Jong, J. Fehrentz, W. M. van Weerden, 2016, EJNMMI Research.

A C-terminal aldehyde insect kinin analog enhances inhibition of weight gain and induces significant mortality in Helicoverpa zea larvae

Jean Martinez, J. Fehrentz, J. Zabrocki, 2003, Peptides.

Evidence Supporting a Role for Constitutive Ghrelin Receptor Signaling in Fasting-Induced Hyperphagia in Male Mice

J. Fehrentz, M. Perelló, J. Epelbaum, 2018, Endocrinology.

Structure and dynamics of G protein-coupled receptor–bound ghrelin reveal the critical role of the octanoyl chain

S. Cantel, A. Milon, J. Fehrentz, 2019, Proceedings of the National Academy of Sciences.

How ligands and signalling proteins affect G-protein-coupled receptors' conformational landscape.

Jean Martinez, J. Fehrentz, J. Banères, 2013, Biochemical Society transactions.

Growth hormone secretagogue receptor signalling affects high‐fat intake independently of plasma levels of ghrelin and LEAP2, in a 4‐day binge eating model

H. Schiöth, J. Fehrentz, M. Perelló, 2019, Journal of neuroendocrinology.

Comparative Study of In Vitro and In Vivo Activities of Bombesin Pseudopeptide Analogs Modified on the C-Terminal Dipeptide Fragment

J. Fehrentz, M. Llinares, J. Azay, 1998, Peptides.

Synthesis and biological evaluation of bombesin constrained analogues.

A. Heitz, J. Fehrentz, O. Chaloin, 2000, Journal of Medicinal Chemistry.

Palatability Can Drive Feeding Independent of AgRP Neurons.

Christophe Magnan, Michael J Krashes, R. Palmiter, 2017, Cell metabolism.

Palatability Can Drive Feeding Independent of AgRP Neurons.

R. Palmiter, M. Krashes, S. Luquet, 2015, Cell metabolism.

On the Central Mechanism Underlying Ghrelin’s Chronic Pro‐Obesity Effects in Rats: New Insights from Studies Exploiting a Potent Ghrelin Receptor Antagonist

J. Fehrentz, S. Dickson, E. Egecioglu, 2009, Journal of neuroendocrinology.

Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex

D. Pérahia, E. Trinquet, B. Mouillac, 2015, Proceedings of the National Academy of Sciences.

Solid Phase Synthesis of C-Terminal Peptide Aldehydes

A. Heitz, Jean Martinez, J. Fehrentz, 1997 .

Synthesis of chiral α-amino-diazoketones on solid support: An access to β-homologated amino acid derivatives

S. Cantel, Jean Martinez, J. Fehrentz, 2004 .

Synthesis of chiral N-protected amino acid esters by the use of UNCAs

K. Kieć‐Kononowicz, J. Fehrentz, J. Martinez, 2004, Letters in Peptide Science.

Peptides mimicking the flap of human renin: synthesis, conformation, and antibody recognition.

R. Seyer, F. Heitz, A. Heitz, 1988, Biochemistry.

Pharmacologic antagonism of ghrelin receptors attenuates development of nicotine induced locomotor sensitization in rats

Jean Martinez, J. Fehrentz, P. Wellman, 2011, Regulatory Peptides.

Synthesis and biological evaluation of C‐terminal hydroxamide analogues of bombesin

A. Heitz, Jean Martinez, J. Fehrentz, 1999, Journal of peptide science : an official publication of the European Peptide Society.

Ghrelin Receptor Ligands: Design and Synthesis of Pseudopeptides and Peptidomimetics

A. Moulin, Jean Martinez, J. Fehrentz, 2014 .

Gastrin-Releasing Peptide Receptor Antagonists for PET Imaging of Prostate Cancer

W. Mcbride, M. Jong, O. Boerman, 2014 .

Growth hormone secretagogues modulate inflammation and fibrosis in mdx mouse model of Duchenne muscular dystrophy

G. Cruciani, A. Torsello, E. Conte, 2023, Frontiers in Immunology.

A study with a functional monomeric GHS-R 1 a receptor reconstituted in lipid discs

Jean Martinez, J. Fehrentz, J. Banères, 2011 .

Effects of Motivational Downshifts on Specific Pavlovian-Instrumental Transfer in Rats

W. Hauber, A. Münster, J. Fehrentz, 2022, The international journal of neuropsychopharmacology.

Utrophin Localization in Normal and Dystrophin‐Deficient Heart

E. Fabbrizio, Jean Martinez, J. Fehrentz, 1994, Circulation.

Ghrelin’s orexigenic action in the lateral hypothalamic area involves indirect recruitment of orexin neurons and arcuate nucleus activation

S. Cantel, H. Schiöth, J. Zigman, 2023, Psychoneuroendocrinology.

Concerted conformational dynamics and water movements in the ghrelin G protein-coupled receptor

P. Bisch, D. Pérahia, S. Cantel, 2021, eLife.

Triazole GHS-R1a antagonists JMV4208 and JMV3002 attenuate food intake, body weight, and adipose tissue mass in mice

A. Moulin, J. Fehrentz, L. Maletínská, 2014, Molecular and Cellular Endocrinology.

On the Central Mechanism Underlying Ghrelin’s Chronic Pro‐Obesity Effects in Rats: New Insights from Studies Exploiting a Potent Ghrelin Receptor Antagonist

J. Fehrentz, E. Egecioglu, L. Karlsson-Lindahl, 2009, Journal of neuroendocrinology.

Selective homodimerization of unprotected peptides using hybrid hydroxydimethylsilane derivatives

Jean Martínez, J. Fehrentz, J. Marie, 2016 .

Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling*

Jean Martinez, J. Fehrentz, S. Denoyelle, 2015, The Journal of Biological Chemistry.

Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor

Jean Martinez, J. Fehrentz, J. Banères, 2012, Proceedings of the National Academy of Sciences.

LEAP2 Impairs the Capability of the Growth Hormone Secretagogue Receptor to Regulate the Dopamine 2 Receptor Signaling

S. Cantel, H. Schiöth, J. Fehrentz, 2021, Frontiers in Pharmacology.