B. Conti

发表

CRF system recruitment mediates dark side of compulsive eating

Pietro Cottone, Bruno Conti, G. Koob, 2009, Proceedings of the National Academy of Sciences.

PGRMC2 is an Intracellular Heme Chaperone Critical for Adipocyte Function

G. Siuzdak, R. Spreafico, D. Kojetin, 2019, Nature.

The 4E-BP growth pathway regulates the effect of ambient temperature on Drosophila metabolism and lifespan

Gil B. Carvalho, B. Conti, I. Drago, 2017, Proceedings of the National Academy of Sciences.

Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma

F. Ciccosanti, G. Fimia, M. Corazzari, 2014, Cell Death and Differentiation.

Transgenic Mice with a Reduced Core Body Temperature Have an Increased Life Span

Raphaelle Winsky-Sommerer, Bruno Conti, Steven Henriksen, 2006, Science.

A Cool Way to Live Long

M. Hansen, B. Conti, M. Hansen, 2013, Cell.

Mapping of the full length and the truncated interleukin-18 receptor alpha in the mouse brain

M. Marcondes, B. Conti, S. Sugama, 2009, Journal of Neuroimmunology.

Molecules affecting hypothalamic control of core body temperature in response to calorie intake

T. Bártfai, B. Conti, 2012, Front. Gene..

High frequency of TNF alleles -238A and -376A in individuals from northern Sardinia.

T. Bártfai, M. C. Morale, B. Marchetti, 2004, Cytokine.

Osteopontin Impacts West Nile virus Pathogenesis and Resistance by Regulating Inflammasome Components and Cell Death in the Central Nervous System at Early Time Points

H. Fox, M. Marcondes, B. Conti, 2017, Mediators of inflammation.

Marin L. Gantner, E. Eury, B. Conti, 2018, iScience.

Reactive oxygen species scavenger N-acetyl cysteine reduces methamphetamine-induced hyperthermia without affecting motor activity in mice

M. Marcondes, B. Conti, A. Galmozzi, 2014, Temperature.

Deciphering the pathways that protect from IL‐13‐mediated potentiation of oxidative stress‐induced dopaminergic nerve cell death

P. Maher, B. Conti, 2017, Cytokine.

Cytokines and fever.

T. Bártfai, B. Conti, C. Andrei, 2004, Frontiers in bioscience : a journal and virtual library.

Interleukin 18 activates MAPKs and STAT3 but not NF-κB in hippocampal HT-22 cells

B. Conti, M. Sánchez-Alavez, N. Brunello, 2014, Brain, Behavior, and Immunity.

Activation of Kappa Opioid Receptor Regulates the Hypothermic Response to Calorie Restriction and Limits Body Weight Loss

G. Siuzdak, B. Conti, Carlos Guijas, 2019, Current Biology.

Interleukin-18 null mutation increases weight and food intake and reduces energy expenditure and lipid substrate utilization in high-fat diet fed mice

E. Zorrilla, B. Conti, 2014, Brain, Behavior, and Immunity.

ROS and Sympathetically Mediated Mitochondria Activation in Brown Adipose Tissue Contribute to Methamphetamine-Induced Hyperthermia

H. Fox, M. Marcondes, M. Wood, 2013, Front. Endocrinol..

AdipoR1 and 2 are expressed on warm sensitive neurons of the hypothalamic preoptic area and contribute to central hyperthermic effects of adiponectin

T. Bártfai, M. Marcondes, B. Conti, 2011, Brain Research.

Downregulation of GPR83 in the hypothalamic preoptic area reduces core body temperature and elevates circulating levels of adiponectin.

T. Bártfai, B. Conti, G. Moroncini, 2012, Metabolism: clinical and experimental.

Stress induced morphological microglial activation in the rodent brain: Involvement of interleukin-18

B. Conti, S. Sugama, M. Hashimoto, 2007, Neuroscience.

Interleukin-18 null mice show diminished microglial activation and reduced dopaminergic neuron loss following acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment

T. Bártfai, B. Conti, S. Sugama, 2004, Neuroscience.

Time course of blood and brain cytokine/chemokine levels following adolescent alcohol exposure and withdrawal in rats.

C. Ehlers, D. Wills, B. Conti, 2019, Alcoholism, clinical and experimental research.

Corticosteroids limit microglial activation occurring during acute stress

B. Conti, S. Sugama, M. Hashimoto, 2013, Neuroscience.

Age- and gender-specific changes of hypocretin immunopositive neurons in C57Bl/6 mice

S. Brownell, B. Conti, 2010, Neuroscience Letters.

Metabolic Characterization of a Mouse Deficient in All Known Leptin Receptor Isoforms

S. Brownell, B. Beutler, T. Bártfai, 2009, Cellular and Molecular Neurobiology.

Cultures of astrocytes and microglia express interleukin 18.

T. Joh, B. Conti, G. Gibson, 1999, Brain research. Molecular brain research.

The adrenal gland is a source of stress-induced circulating IL-18

F. Dhabhar, N. Koibuchi, B. Conti, 2006, Journal of Neuroimmunology.

Night eating and obesity in the EP3R-deficient mouse

S. Brownell, T. Bártfai, B. Conti, 2007, Proceedings of the National Academy of Sciences.

IL-1 family nomenclature

L. Joosten, M. Netea, Dirk E. Smith, 2010, Nature Immunology.

Toll-like receptors as pharmacological targets

T. Bártfai, M. Behrens, J. Rebek, 2006 .

Age-associated changes in microglia activation and Sirtuin-1- chromatin binding patterns

H. Fox, M. Marcondes, B. Conti, 2022, Aging.

ALCOHOL_2017_243 Intermittent voluntary ethanol consumption combined with ethanol vapor exposure during adolescence increases drinking and alters other behaviors in adulthood in female and male rats

C. Ehlers, D. Wills, B. Conti, 2018 .

Inducible cAMP Early Repressor Can Modulate Tyrosine Hydroxylase Gene Expression after Stimulation of cAMP Synthesis*

T. Joh, Kwang-Soo Kim, J. Cubells, 1996, The Journal of Biological Chemistry.

Neurotoxic APP C-terminal and β-amyloid domains colocalize in the nuclei of substantia nigra pars reticulata neurons undergoing delayed degeneration

B. Volpe, B. Conti, L. Degiorgio, 2000, Brain Research.

Constitutive and LPS-regulated expression of interleukin-18 receptor beta variants in the mouse brain

F. Caggia, M. Marcondes, B. Conti, 2011, Brain, Behavior, and Immunity.

Cross-Linking Cellular Prion Protein Triggers Neuronal Apoptosis in Vivo

B. Volpe, E. Masliah, J. Criado, 2004, Science.

Metabolic Depression and Increased Reactive Oxygen Species Production by Isolated Mitochondria at Moderately Lower Temperatures*

H. Bajova, M. Marcondes, B. Conti, 2010, The Journal of Biological Chemistry.

ABHD12 and LPCAT3 Interplay Regulates a Lyso-phosphatidylserine-C20:4 Phosphatidylserine Lipid Network Implicated in Neurological Disease.

B. Cravatt, P. Tontonoz, B. Conti, 2020, Biochemistry.

Contributions of neuronal prion protein on sleep recovery and stress response following sleep deprivation

J. Criado, B. Conti, G. Moroncini, 2007, Brain Research.

Monoacylglycerol Lipase Regulates Fever Response

D. Nomura, B. Cravatt, B. Conti, 2015, PloS one.

Molecular basis of central thermosensation.

B. Conti, 2018, Handbook of clinical neurology.

Multiple sclerosis and anti-Plasmodium falciparum innate immune response

M. C. Morale, B. Marchetti, G. Rosati, 2007, Journal of Neuroimmunology.

Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine

D. Hoyer, T. Bártfai, M. C. Morale, 2007, Molecular Psychiatry.

The Proinflammatory Cytokine Interleukin 18 Regulates Feeding by Acting on the Bed Nucleus of the Stria Terminalis

E. Zorrilla, B. Conti, G. Moroncini, 2016, The Journal of Neuroscience.

Insulin-like growth factor 1 receptor regulates hypothermia during calorie restriction

T. Bártfai, M. Holzenberger, B. Conti, 2017, Proceedings of the National Academy of Sciences.

A role for galanin in antidepressant actions with a focus on the dorsal raphe nucleus.

T. Bártfai, M. Behrens, P. Sanna, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Activation of σ-Receptors Induces Binge-like Drinking in Sardinian Alcohol-Preferring Rats

M. R. Iyer, G. Koob, E. Zorrilla, 2011, Neuropsychopharmacology.

Cytokine Receptors in the Brain

S. Brownell, T. Bártfai, M. Behrens, 2008 .

Insights into the roles of the inflammatory mediators IL-1, IL-18 and PGE2 in obesity and insulin resistance.

E. Zorrilla, T. Bártfai, H. Gram, 2008, Swiss medical weekly.

Metabolic adaptation to calorie restriction

G. Siuzdak, B. Conti, Carlos Guijas, 2020, Science Signaling.

Neuroimmunology of the Interleukins 13 and 4

P. Maher, B. Conti, Simone Mori, 2016, Brain sciences.

Gonadal hormones influence core body temperature during calorie restriction

B. Conti, Rigo Cintron-Colon, M. Sánchez-Alavez, 2019, Temperature.

Sex- and age-specific differences in core body temperature of C57Bl/6 mice

B. Conti, M. Sánchez-Alavez, S. Alboni, 2011, AGE.

The activation of P2X7 receptor induces cathepsin D‐dependent production of a 20‐kDa form of IL‐1β under acidic extracellular pH in LPS‐primed microglial cells

B. Conti, S. Sugama, A. Sekigawa, 2011, Journal of neurochemistry.

Uncoupling protein 2 protects dopaminergic neurons from acute 1,2,3,6‐methyl‐phenyl‐tetrahydropyridine toxicity

Pamela Maher, Bruno Conti, Flint Beal, 2005, Journal of neurochemistry.

A Specific Role for NR2A-Containing NMDA Receptors in the Maintenance of Parvalbumin and GAD67 Immunoreactivity in Cultured Interneurons

T. Bártfai, M. Behrens, B. Conti, 2006, The Journal of Neuroscience.

Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency

E. Zorrilla, T. Bártfai, B. Conti, 2007, Proceedings of the National Academy of Sciences.

Prolonged in vivo gene expression driven by a tyrosine hydroxylase promoter in a defective herpes simplex virus amplicon vector.

T. Joh, H. Federoff, R. Starr, 1996, Human gene therapy.

Electrophysiological properties and thermosensitivity of mouse preoptic and anterior hypothalamic neurons in culture

H. Korn, T. Bártfai, M. Behrens, 2005, Neuroscience.

Time course of microglia activation and brain and blood cytokine/chemokine levels following chronic ethanol exposure and protracted withdrawal in rats.

C. Ehlers, D. Wills, B. Conti, 2019, Alcohol.

Hypothalamic–pituitary–adrenal axis disregulation in PrPC-null mice

J. Criado, B. Conti, G. Moroncini, 2008, Neuroreport.

Hypothalamic and dietary control of temperature-mediated longevity

Bruno Conti, T. Bártfai, B. Morrison, 2010, Ageing Research Reviews.

Interleukin 18 in the CNS

B. Conti, S. Sugama, D. Cervia, 2010, Journal of Neuroinflammation.

Cutting Edge: IL-13Rα1 Expression in Dopaminergic Neurons Contributes to Their Oxidative Stress–Mediated Loss following Chronic Peripheral Treatment with Lipopolysaccharide

D. Nomura, T. Bártfai, Kwang-Soo Kim, 2012, The Journal of Immunology.

A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation

B. Cravatt, B. Conti, Christopher M. Joslyn, 2016, eLife.

The sigma receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking

M. R. Iyer, G. Koob, E. Zorrilla, 2008, Neuropsychopharmacology.

Effects of chronic mental stress and atherogenic diet on the immune inflammatory environment in mouse aorta

B. Conti, L. Curtiss, H. Bradlow, 2011, Brain, Behavior, and Immunity.

Interleukin-18 and stress

B. Conti, S. Sugama, 2008, Brain Research Reviews.

Interleukin-18 mRNA expression in the rat pituitary gland

B. Conti, S. Sugama, A. Teramoto, 2006, Journal of Neuroimmunology.

Neurons of the superior nucleus of the medial habenula and ependymal cells express IL-18 in rat CNS

T. Joh, B. Conti, S. Sugama, 2002, Brain Research.

Modulation of IL-18 Production in the Adrenal Cortex following Acute ACTH or Chronic Corticosterone Treatment

B. Volpe, T. Joh, B. Conti, 2000, Neuroimmunomodulation.

Tissue-Specific Expression of Rat IL-18 Gene and Response to Adrenocorticotropic Hormone Treatment

T. Joh, B. Conti, S. Sugama, 2000 .

Hormone Treatment and Response to Adrenocorticotropic Tissue-Specific Expression of Rat IL-18 Gene

T. Joh, B. Conti, S. Sugama, 2000 .

Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition

H. Overkleeft, Juan Zhou, B. Cravatt, 2015, Proceedings of the National Academy of Sciences.

Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation

D. Nomura, J. Long, B. Cravatt, 2011, Science.

Two single nucleotide polymorphisms in IL13 and IL13RA1 from individuals with idiopathic Parkinson’s disease increase cellular susceptibility to oxidative stress

M. C. Morale, P. Maher, Q. Peng, 2020, Brain, Behavior, and Immunity.

Intermittent voluntary ethanol consumption combined with ethanol vapor exposure during adolescence increases drinking and alters other behaviors in adulthood in female and male rats.

C. Ehlers, D. Wills, B. Conti, 2018, Alcohol.

Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons

S. Henriksen, B. Chesebro, J. Criado, 2005, Neurobiology of Disease.

Diet, behavior and immunity across the lifespan

C. Jasoni, T. Reyes, B. Conti, 2015, Neuroscience & Biobehavioral Reviews.

Differential microglial activation between acute stress and lipopolysaccharide treatment

B. Conti, S. Sugama, M. Hashimoto, 2009, Journal of Neuroimmunology.

LipopolysaccharideChronic Peripheral Treatment with Mediated Loss following - Oxidative Stress Dopaminergic Neurons Contributes to Their 1 Expression in a Cutting Edge: IL-13R

D. Nomura, Kwang-Soo Kim, B. Morrison, 2012 .

Fever

T. Bártfai, B. Conti, 2010, TheScientificWorldJournal.

Unique and cell-type-specific tyrosine hydroxylase gene expression.

T. Joh, S. Cho, B. Conti, 1998, Advances in pharmacology.

PGRMC2 is an Intracellular Heme Chaperone Critical for Adipocyte Function

G. Siuzdak, R. Spreafico, D. Kojetin, 2019, Nature.

Osteopontin Expression in the Brain Triggers Localized Inflammation and Cell Death When Immune Cells Are Activated by Pertussis Toxin

H. Fox, B. Conti, Nikki Bortell, 2014, Mediators of inflammation.

Insulin Causes Hyperthermia by Direct Inhibition of Warm-Sensitive Neurons

J. Eberwine, T. Bártfai, H. Kolb, 2009, Diabetes.

Lack of interleukin-13 receptor α1 delays the loss of dopaminergic neurons during chronic stress

P. Maher, M. Sanna, B. Conti, 2017, Journal of Neuroinflammation.

Lack of interleukin-13 receptor α1 delays the loss of dopaminergic neurons during chronic stress

T. Michel, P. Maher, M. Sanna, 2017, Journal of Neuroinflammation.

Interleukin‐1 System in CNS Stress

T. Bártfai, A. Vezzani, B. Conti, 2007, Annals of the New York Academy of Sciences.

Prostaglandin E2 that triggers fever is synthesized through an endocannabinoid- dependent pathway

B. Conti, 2016, Temperature.

Osteopontin Impacts West Nile virus Pathogenesis and Resistance by Regulating Inflammasome Components and Cell Death in the Central Nervous System at Early Time Points

H. Fox, B. Conti, Nikki Bortell, 2017, Mediators of inflammation.

Journal of Neuroinflammation Interleukin 18 in the Cns

B. Conti, S. Sugama, D. Cervia, 2022 .

Supporting Online Material Material and Methods Som Text Figs. S1 to S7 Tables S1 and S2 References Transgenic Mice with a Reduced Core Body Temperature Have an Increased Life Span

S. Henriksen, S. Brownell, E. Zorrilla, 2022 .