S. Rubakhin

J. Sweedler, S. Rubakhin, Lingyang Zhu, 2018, Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors.

A systematic review of epinephrine stability and sterility with storage in a syringe

J. Sweedler, S. Rubakhin, I. Uzoaru, 2022 .

Secondary Ion Mass Spectrometry Imaging of Molecular Distributions in Cultured Neurons and Their Processes: Comparative Analysis of Sample Preparation

J. Sweedler, S. Rubakhin, Kevin R. Tucker, 2012, Journal of The American Society for Mass Spectrometry.

Opposite effects of interleukin-2 and interleukin-4 on GABA-induced inward currents of dialysed Lymnaea neurons.

A. Szücs, S. Rubakhin, G. Stefano, 1997, General pharmacology.

Collection of peptides released from single neurons with particle-embedded monolithic capillaries followed by detection with matrix-assisted laser desorption/ionization mass spectrometry.

J. Sweedler, S. Rubakhin, Yi Fan, 2011, Analytical chemistry.

Imaging mass spectrometry: fundamentals and applications to drug discovery.

Jonathan V Sweedler, J. Sweedler, S. Rubakhin, 2005, Drug discovery today.

Effects of exercise and dietary epigallocatechin gallate and β-alanine on skeletal muscle in aged mice.

J. Sweedler, Stephen A. Martin, B. Pence, 2016, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

Stimulation and release from neurons via a dual capillary collection device interfaced to mass spectrometry.

J. Sweedler, S. Rubakhin, Yi Fan, 2013, The Analyst.

Free d-Aspartate in Nonmammalian Animals: Detection, Localization, Metabolism, and Function

J. Sweedler, S. Rubakhin, Amit V Patel, 2016 .

Profiling 26,000 Aplysia californica neurons by single cell mass spectrometry reveals neuronal populations with distinct neuropeptide profiles

J. Sweedler, S. Rubakhin, E. Romanova, 2022, The Journal of biological chemistry.

Pro ﬁ ling 26,000 Aplysia californica neurons by single cell mass spectrometry reveals neuronal populations with distinct neuropeptide pro ﬁ les

J. Sweedler, S. Rubakhin, E. Romanova, 2022 .

d-Amino Acids and Classical Neurotransmitters in Healthy and Type 2 Diabetes-Affected Human Pancreatic Islets of Langerhans

J. Sweedler, S. Rubakhin, Chengyang Liu, 2022, Metabolites.

Mechanical Tension Modulates Local and Global Vesicle Dynamics in Neurons

T. Saif, S. Rubakhin, W. Ahmed, 2012, Cellular and Molecular Bioengineering.

Deterministic Integration of Biological and Soft Materials onto 3D Microscale Cellular Frameworks

John A Rogers, Kyung-In Jang, Zheng Yan, 2017, Advanced biosystems.

Subcellular analysis of D-aspartate.

J. Sweedler, S. Rubakhin, Hai Miao, 2005, Analytical chemistry.

3D Particle‐Free Printing of Biocompatible Conductive Hydrogel Platforms for Neuron Growth and Electrophysiological Recording

R. Nuzzo, J. Sweedler, S. Rubakhin, 2021, Advanced functional materials.

PRODUCTION OF NITRIC OXIDE WITHIN THE APLYSIA CALIFORNICA NERVOUS SYSTEM.

J. Sweedler, S. Rubakhin, E. Romanova, 2010, ACS chemical neuroscience.

Lutein and Brain Function

John W. Erdman, Jonathan V. Sweedler, Martha Neuringer, 2015, Foods.

Confirmation of peak assignments in capillary electrophoresis using immunoprecipitation. Application to D-aspartate measurements in neurons.

J. Sweedler, S. Rubakhin, Hai Miao, 2006, Journal of chromatography. A.

Met-enkephalin and morphiceptin modulate a GABA-induced inward current in the CNS of Lymnaea stagnalis L.

A. Szücs, S. Rubakhin, G. Stefano, 1996, General pharmacology.

PACAP and Other Neuropeptide Targets Link Chronic Migraine and Opioid-induced Hyperalgesia in Mouse Models*

J. Sweedler, S. Rubakhin, E. Romanova, 2019, Molecular & Cellular Proteomics.

PACAP and other neuropeptides link chronic migraine and opioid-induced hyperalgesia in mouse models

J. Sweedler, S. Rubakhin, E. Romanova, 2019 .

13C-lutein is differentially distributed in tissues of an adult female rhesus macaque following a single oral administration: a pilot study.

M. Kuchan, J. Sweedler, S. Rubakhin, 2019, Nutrition research.

Data-Driven and Machine Learning-Based Framework for Image-Guided Single-Cell Mass Spectrometry.

Daniel Coelho de Castro, J. Sweedler, S. Rubakhin, 2023, Journal of proteome research.

Image-guided MALDI mass spectrometry for high-throughput single-organelle characterization

J. Sweedler, S. Rubakhin, E. Romanova, 2021, Nature Methods.

Single-Cell Classification Using Mass Spectrometry Through Interpretable Machine Learning.

J. Sweedler, S. Rubakhin, Daniel C. Castro, 2020, Analytical chemistry.

Lipid Analysis of 30 000 Individual Rodent Cerebellar Cells Using High-Resolution Mass Spectrometry.

Elizabeth K. Neumann, J. Sweedler, S. Rubakhin, 2019, Analytical chemistry.

Detection of nitric oxide in single cells.

J. Sweedler, S. Rubakhin, Xiaoying Ye, 2008, The Analyst.

Top-Down Proteomics Enables Comparative Analysis of Brain Proteoforms Between Mouse Strains.

Joseph B. Greer, N. Kelleher, R. LeDuc, 2018, Analytical chemistry.

Profiling signaling peptides in single mammalian cells using mass spectrometry.

Jonathan V Sweedler, W. Greenough, J. Sweedler, 2006, Analytical chemistry.

Removing Formaldehyde-Induced Peptidyl Crosslinks Enables Mass Spectrometry Imaging of Peptide Hormone Distributions from Formalin-Fixed Paraffin-Embedded Tissues.

M. Atkinson, J. Sweedler, S. Rubakhin, 2020, Angewandte Chemie.

Identification and characterization of homologues of vertebrate beta-thymosin in the marine mollusk Aplysia californica.

Jonathan V Sweedler, Neil L Kelleher, Elena V Romanova, 2006, Journal of mass spectrometry : JMS.

Measuring the peptides in individual organelles with mass spectrometry

Jonathan V. Sweedler, Stanislav S. Rubakhin, J. Sweedler, 2000, Nature Biotechnology.

A unique combination of micronutrients rejuvenates cognitive performance in aged mice

J. Sweedler, C. Rendeiro, S. Rubakhin, 2017, Behavioural Brain Research.

Identification and Characterization of the Feeding Circuit-Activating Peptides, a Novel Neuropeptide Family ofAplysia

K R Weiss, J. Jing, K. R. Weiss, 2002, The Journal of Neuroscience.

Droplet Microfluidics with MALDI-MS Detection: The Effects of Oil Phases in GABA Analysis

J. Sweedler, S. Rubakhin, Rashid Bashir, 2021, ACS measurement science Au.

Independent optimization of capillary electrophoresis separation and native fluorescence detection conditions for indolamine and catecholamine measurements.

J. Sweedler, S. Rubakhin, J V Sweedler, 1999, Analytical chemistry.

Subcellular omics: a new frontier pushing the limits of resolution, complexity and throughput

M. Bucan, Junhyong Kim, James Zou, 2023, Nature Methods.

Insulin Prohormone Processing, Distribution, and Relation to Metabolism in Aplysia californica

K. R. Weiss, I. Kupfermann, F. Vilim, 1999, The Journal of Neuroscience.

monitoring activity-dependent peptide release from the CNS using single-bead solid-phase extraction and MALDI TOF MS detection.

Jonathan V Sweedler, J. Sweedler, N. Hatcher, 2005, Analytical chemistry.

Dopamine-modified TiO2 monolith-assisted LDI MS imaging for simultaneous localization of small metabolites and lipids in mouse brain tissue with enhanced detection selectivity and sensitivity

M. Gillette, J. Sweedler, S. Rubakhin, 2017, Chemical Science.

Mass spectrometry-based characterization of endogenous peptides and metabolites in small volume samples.

J. Sweedler, Ta-Hsuan Ong, S. Rubakhin, 2015, Biochimica et biophysica acta.

d‐Aspartate as a putative cell–cell signaling molecule in the Aplysia californica central nervous system

J. Sweedler, S. Rubakhin, Hai Miao, 2006, Journal of neurochemistry.

Improved identification and quantitation of mature endogenous peptides in the rodent hypothalamus using a rapid conductive sample heating system.

Jonathan V Sweedler, Elena V Romanova, J. Sweedler, 2017, The Analyst.

Neuropeptidomics of the Supraoptic Rat Nucleus

Martha U. Gillette, Jonathan V. Sweedler, Neil L. Kelleher, 2008, Journal of proteome research.

Serotonin catabolism in the central and enteric nervous systems of rats upon induction of serotonin syndrome

J. Sweedler, S. Rubakhin, Leah N. Squires, 2007, Journal of neurochemistry.

Carrot solution culture bioproduction of uniformly labeled 13C-lutein and in vivo dosing in non-human primates

M. Kuchan, J. Sweedler, S. Rubakhin, 2017, Experimental biology and medicine.

Mass Spectrometry Imaging and GC-MS Profiling of the Mammalian Peripheral Sensory-Motor Circuit

J. Sweedler, S. Rubakhin, A. Ulanov, 2015, Journal of The American Society for Mass Spectrometry.

Quantitative Imprint Mass Spectrometry Imaging of Endogenous Ceramides in Rat Brain Tissue with Kinetic Calibration.

J. Sweedler, S. Rubakhin, Qian Wu, 2020, Analytical chemistry.

On-Tissue Derivatization via Electrospray Deposition for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Endogenous Fatty Acids in Rat Brain Tissues

J. Sweedler, S. Rubakhin, T. Comi, 2016, Analytical chemistry.

Progress toward single cell metabolomics.

Jonathan V Sweedler, Eric J Lanni, J. Sweedler, 2013, Current opinion in biotechnology.

Single Cell Profiling Using Ionic Liquid Matrix-Enhanced Secondary Ion Mass Spectrometry for Neuronal Cell Type Differentiation.

Sage J. B. Dunham, J. Sweedler, Thanh D. Do, 2017, Analytical chemistry.

Removing Formaldehyde‐Induced Peptidyl Crosslinks Enables Mass Spectrometry Imaging of Peptide Hormone Distributions from Formalin‐Fixed Paraffin‐Embedded Tissues

J. Sweedler, S. Rubakhin, C. Wasserfall, 2020, Angewandte Chemie.

Peptidomics and Secretomics of the Mammalian Peripheral Sensory-Motor System

J. Sweedler, S. Rubakhin, Emily G Tillmaand, 2015, Journal of the American Society for Mass Spectrometry.

Enhancing the Throughput of FT Mass Spectrometry Imaging Using Joint Compressed Sensing and Subspace Modeling.

Daniel C. Castro, Fan Lam, Jonathan V. Sweedler, 2021, Analytical chemistry.

Multimodal Chemical Analysis of the Brain by High Mass Resolution Mass Spectrometry and Infrared Spectroscopic Imaging.

Elizabeth K. Neumann, M. Gillette, R. Bhargava, 2018, Analytical chemistry.

Classification of Large Cellular Populations and Discovery of Rare Cells Using Single Cell Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

J. Sweedler, Ta-Hsuan Ong, D. Kissick, 2015, Analytical chemistry.

MALDI MS Guided Liquid Microjunction Extraction for Capillary Electrophoresis–Electrospray Ionization MS Analysis of Single Pancreatic Islet Cells

Troy J Comi, Jonathan V Sweedler, J. Sweedler, 2017, Analytical chemistry.

MALDI Mass Spectrometry Imaging of Neuronal Cell Cultures

Tyler A. Zimmerman, J. Sweedler, S. Rubakhin, 2011, Journal of the American Society for Mass Spectrometry.

The modified-bead stretched sample method: development and application to MALDI-MS imaging of protein localization in the spinal cord.

Tyler A. Zimmerman, J. Sweedler, S. Rubakhin, 2011, Chemical science.

Massively parallel sample preparation for the MALDI MS analyses of tissues.

Jonathan V Sweedler, J. Sweedler, S. Rubakhin, 2006, Analytical chemistry.

Analysis of serotonin release from single neuron soma using capillary electrophoresis and laser-induced fluorescence with a pulsed deep-UV NeCu laser

J. Sweedler, S. Rubakhin, Hai Miao, 2003, Analytical and bioanalytical chemistry.

Chemical Decrosslinking-Based Peptide Characterization of Formaldehyde-Fixed Rat Pancreas Using Fluorescence-Guided Single-Cell Mass Spectrometry.

J. Sweedler, S. Rubakhin, Dong‐Kyu Lee, 2023, Analytical chemistry.

Spatial profiling with MALDI MS: distribution of neuropeptides within single neurons.

Jonathan V Sweedler, W. Greenough, J. Sweedler, 2003, Analytical chemistry.

Analysis of endogenous nucleotides by single cell capillary electrophoresis-mass spectrometry.

Jonathan V Sweedler, J. Sweedler, S. Rubakhin, 2014, The Analyst.

Methodologies for Metabolomics: Mass Spectrometry–Based Methodologies for Single-Cell Metabolite Detection and Identification

J. Sweedler, S. Rubakhin, P. Nemes, 2010 .

Vitamin E imaging and localization in the neuronal membrane.

Jonathan V Sweedler, J. Sweedler, S. Rubakhin, 2005, Journal of the American Chemical Society.

Measuring D-amino acid-containing neuropeptides with capillary electrophoresis.

J. Sweedler, S. Rubakhin, Michael A. Ewing, 2005, The Analyst.

Biomolecular Imaging with a C60-SIMS/MALDI Dual Ion Source Hybrid Mass Spectrometer: Instrumentation, Matrix Enhancement, and Single Cell Analysis

Sage J. B. Dunham, J. Sweedler, S. Rubakhin, 2014, Journal of The American Society for Mass Spectrometry.

Mass spectrometry imaging and profiling of single cells.

J. Sweedler, S. Rubakhin, Eric J. Lanni, 2012, Journal of proteomics.

Chapter 13: Imaging of cells and tissues with mass spectrometry: adding chemical information to imaging.

Tyler A. Zimmerman, J. Sweedler, S. Rubakhin, 2008, Methods in cell biology.

Quantitative Measurements of Cell−Cell Signaling Peptides with Single-Cell MALDI MS

J. Sweedler, S. Rubakhin, 2008, Analytical chemistry.

Characterizing peptides in individual mammalian cells using mass spectrometry

Jonathan V Sweedler, J. Sweedler, S. Rubakhin, 2007, Nature Protocols.

Characterization of the Aplysia californica cerebral ganglion F cluster.

J. Sweedler, S. Rubakhin, T. Moroz, 1999, Journal of neurophysiology.

Multidimensional Top-Down Proteomics of Brain Region-Specific Mouse Brain Proteoforms Responsive to Cocaine and Estradiol.

Richard D. LeDuc, Ryan T. Fellers, Joseph B. Greer, 2019, Journal of proteome research.

Characterization of the GABA response on identified dialysed Lymnaea neurons.

A. Szücs, S. Rubakhin, K. Rózsa, 1996, General pharmacology.

Analysis of cellular release using capillary electrophoresis and matrix assisted laser desorption/ionization‐time of flight‐mass spectrometry

J. Sweedler, S. Rubakhin, J. Page, 2001, Electrophoresis.

Ubiquitous presence of argininosuccinate at millimolar levels in the central nervous system of Aplysia californica

S. Rubakhin, Won Kim, Xiaoying Ye, 2006, Journal of neurochemistry.

Distinct Mechanisms Produce Functionally Complementary Actions of Neuropeptides That Are Structurally Related But Derived from Different Precursors

Vladimir Brezina, Klaudiusz R Weiss, Jonathan V Sweedler, 2010, The Journal of Neuroscience.

Quantitative reflection imaging of fixed Aplysia californica pedal ganglion neurons on nanostructured plasmonic crystals.

J. Rogers, R. Nuzzo, J. Sweedler, 2013, The journal of physical chemistry. B.

Qualitative and quantitative metabolomic investigation of single neurons by capillary electrophoresis electrospray ionization mass spectrometry

J. Sweedler, S. Rubakhin, Jordan T. Aerts, 2013, Nature Protocols.

Stretched tissue mounting for MALDI mass spectrometry imaging.

J. Sweedler, S. Rubakhin, Eric J. Lanni, 2011, Analytical chemistry.

D-Alanine in the islets of Langerhans of rat pancreas.

J. Sweedler, S. Rubakhin, Nobutoshi Ota, 2014, Biochemical and biophysical research communications.

Mass Spectrometry Imaging

Jonathan V. Sweedler, Stanislav S. Rubakhin, J. Sweedler, 2010, Methods in Molecular Biology.

Single-Cell and Subcellular Analysis Using Ultrahigh Resolution 21 T MALDI FTICR Mass Spectrometry.

Daniel Coelho de Castro, Chad R. Weisbrod, J. Sweedler, 2023, Analytical chemistry.

Ganglion F Cluster Characterization of the Aplysia californicaCerebral

J. Sweedler, S. Rubakhin, Lingjun Li, 2013 .

Top-down Proteomics of 10,000 Single Brain Cells

Ryan T. Fellers, Bryan P. Early, Joseph B. Greer, 2023, bioRxiv.

Integrative Multiscale Biochemical Mapping of the Brain via Deep-Learning-Enhanced High-Throughput Mass Spectrometry

Daniel Coelho de Castro, F. Lam, J. Sweedler, 2023, bioRxiv.

Characterizing RNA Modifications in Single Neurons using Mass Spectrometry.

J. Sweedler, S. Rubakhin, K. Clark, 2022, Journal of visualized experiments : JoVE.

Single-Neuron RNA Modification Analysis by Mass Spectrometry: Characterizing RNA Modification Patterns and Dynamics with Single-Cell Resolution.

J. Sweedler, S. Rubakhin, K. Clark, 2021, Analytical chemistry.

Cerebrin prohormone processing, distribution and action in Aplysia californica

J. Jing, K. R. Weiss, K. Weiss, 2001, Journal of neurochemistry.

Direct assay of Aplysia tissues and cells with laser desorption/ionization mass spectrometry on porous silicon.

J. Sweedler, P. Bohn, S. Rubakhin, 2001, Journal of mass spectrometry : JMS.

Biodistribution and racemization of gut-absorbed l/d-alanine in germ-free mice

S. Rubakhin, E. Romanova, Tianxiang Qiu, 2023, Communications biology.

One-step sampling, extraction, and storage protocol for peptidomics using dihydroxybenzoic Acid.

J. Sweedler, S. Rubakhin, E. Romanova, 2008, Analytical Chemistry.

Optically Guided Single Cell Mass Spectrometry of Rat Dorsal Root Ganglia to Profile Lipids, Peptides and Proteins.

Elizabeth K Neumann, Thanh D Do, Troy J Comi, 2018, Chemphyschem : a European journal of chemical physics and physical chemistry.

Synthesis, accumulation, and release of d‐aspartate in the Aplysia californica CNS

J. Sweedler, N. Hatcher, S. Rubakhin, 2010, Journal of neurochemistry.

Single-neuron analysis using CE combined with MALDI MS and radionuclide detection.

J. Sweedler, S. Rubakhin, J. Page, 2002, Analytical chemistry.

Measurement of nitric oxide by 4,5-diaminofluorescein without interferences.

J. Sweedler, S. Rubakhin, Won Kim, 2004, The Analyst.

Behavioral changes induced by GABA-receptor agonists in Lymnaea stagnalis L.

S. Rubakhin, K. S.-rozsa, E. Romanova, 1996, General pharmacology.

Single‐Cell Mass Spectrometry

Jonathan V. Sweedler, Stanislav S. Rubakhin, J. Sweedler, 2010 .

A neuron-in-capillary platform for facile collection and mass spectrometric characterization of a secreted neuropeptide

J. Sweedler, S. Rubakhin, Yi Fan, 2016, Scientific Reports.

Engineering the morphology and electrophysiological parameters of cultured neurons by microfluidic surface patterning

Ralph G Nuzzo, Jonathan V Sweedler, Elena V Romanova, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Targeted single-cell microchemical analysis: MS-based peptidomics of individual paraformaldehyde-fixed and immunolabeled neurons.

J. Sweedler, S. Rubakhin, S. Neupert, 2012, Chemistry & biology.

Mass spectrometric imaging of the nervous system.

M. Heien, J. Sweedler, N. Hatcher, 2007, Current pharmaceutical design.

Dopamine-modified TiO2 monolith-assisted LDI MS imaging for simultaneous localization of small metabolites and lipids in mouse brain tissue with enhanced detection selectivity and sensitivity

M. Gillette, J. Sweedler, S. Rubakhin, 2017, Chemical science.

A novel series of metazoan L/D peptide isomerases

S. Rubakhin, Hua-Chia Tai, Harvey M. Andersen, 2024, The Journal of biological chemistry.

Stimulation and release from neurons via a dual capillary collection device interfaced to mass spectrometry.

J. Sweedler, S. Rubakhin, Yi Fan, 2013, The Analyst.

3D-Printed pHEMA Materials for Topographical and Biochemical Modulation of Dorsal Root Ganglion Cell Response.

R. Nuzzo, G. Popescu, J. Sweedler, 2017, ACS applied materials & interfaces.