D. Kuntz

发表

Machine-Learning-Accelerated Perovskite Crystallization

E. Sargent, G. Privé, M. Askerka, 2020, Matter.

Evaluation of docking programs for predicting binding of Golgi α‐mannosidase II inhibitors: A comparison with crystallography

Sandrine Gerber-Lemaire, Christopher R. Corbeil, Nicolas Moitessier, 2007, Proteins.

A combined STD-NMR/molecular modeling protocol for predicting the binding modes of the glycosidase inhibitors kifunensine and salacinol to Golgi alpha-mannosidase II.

B. M. Pinto, D. Kuntz, D. Rose, 2005, Biochemistry.

Functionalized pyrrolidine inhibitors of human type II alpha-mannosidases as anti-cancer agents: optimizing the fit to the active site.

R. Janzer, L. Juillerat-Jeanneret, D. Kuntz, 2008, Bioorganic & medicinal chemistry.

Structural analysis of Golgi alpha-mannosidase II inhibitors identified from a focused glycosidase inhibitor screen.

S. Withers, D. Kuntz, D. Rose, 2008, Biochemistry.

Random Mutagenesis Reveals Residues of JAK2 Critical in Evading Inhibition by a Tyrosine Kinase Inhibitor

D. Barber, D. Kuntz, D. Rose, 2012, PloS one.

Immobilised enzyme cascade for targeted glycosylation

K. Polizzi, D. Kuntz, C. Kontoravdi, 2022, bioRxiv.

High-Throughput Evaluation of Emission and Structure in Reduced-Dimensional Perovskites

Isaac Tamblyn, O. Voznyy, E. Sargent, 2022, ACS central science.

Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors: Optimization of Whole-Cell Anticryptococcal Activity and Insights into the Structural Origins of Cryptococcal Selectivity.

L. Cowen, D. Krysan, G. Privé, 2021, Journal of medicinal chemistry.

Expression and purification of sea raven type II antifreeze protein from Drosophila melanogaster S2 cells.

P. Davies, D. Kuntz, D. Rose, 2006, Protein expression and purification.

Overcoming multi‐drug resistance using an intracellular anti‐MDR1 sFv

T. Tsuruo, N. Saijo, K. Kasono, 2001, International journal of cancer.

Inhibition of recombinant human maltase glucoamylase by salacinol and derivatives

B. M. Pinto, D. Kuntz, B. Nichols, 2006, The FEBS journal.

Antibody C219 recognizes an alpha-helical epitope on P-glycoprotein.

Jean M. H. van den Elsen, D. Kuntz, D. Rose, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma

L. Kay, S. Trudel, R. Sprangers, 2009, Leukemia.

Golgi α-mannosidase II cleaves two sugars sequentially in the same catalytic site

D. Kuntz, D. Rose, N. Shah, 2008, Proceedings of the National Academy of Sciences.

Potent glucosidase inhibitors: de-O-sulfonated ponkoranol and its stereoisomer.

B. M. Pinto, D. Kuntz, D. Rose, 2010, Organic letters.

Synthesis and biological evaluation of heteroanalogues of kotalanol and de-O-sulfonated kotalanol.

B. M. Pinto, S. Mohan, D. Kuntz, 2010, Organic letters.

Crystallographic analysis of the interactions of Drosophila melanogaster Golgi α-mannosidase II with the naturally occurring glycomimetic salacinol and its analogues

B. M. Pinto, D. Kuntz, D. Rose, 2005 .

Structural Investigation of the Binding of 5‐Substituted Swainsonine Analogues to Golgi α‐Mannosidase II

D. Kuntz, Y. Uto, H. Hori, 2010, Chembiochem : a European journal of chemical biology.

Synthesis, enzymatic activity, and X-ray crystallography of an unusual class of amino acids.

D. Kuntz, Wang Chen, D. Rose, 2006, Bioorganic & medicinal chemistry.

Structure of Golgi α‐mannosidase II: a target for inhibition of growth and metastasis of cancer cells

D. Kuntz, D. Rose, D R Rose, 2001, The EMBO journal.

Structural basis of the inhibition of Golgi alpha-mannosidase II by mannostatin A and the role of the thiomethyl moiety in ligand-protein interactions.

Robert J Woods, R. Woods, D. Kuntz, 2006, Journal of the American Chemical Society.

Synthesis of a biologically active isomer of kotalanol, a naturally occurring glucosidase inhibitor.

B. M. Pinto, D. Kuntz, D. Rose, 2010, Bioorganic & medicinal chemistry.

The role of the active site Zn in the catalytic mechanism of the GH38 Golgi α-mannosidase II: Implications from noeuromycin inhibition

D. Kuntz, M. Bols, D. Rose, 2006 .

5-Thio-d-glycopyranosylamines and their amidinium salts as potential transition-state mimics of glycosyl hydrolases: synthesis, enzyme inhibitory activities, X-ray crystallography, and molecular modeling

B. Svensson, B. M. Pinto, D. Kuntz, 2005 .

Insights into the Mechanism of Drosophila melanogaster Golgi α-Mannosidase II through the Structural Analysis of Covalent Reaction Intermediates*

S. Withers, D. Kuntz, D. Rose, 2003, Journal of Biological Chemistry.

High level expression in Escherichia coli of soluble, enzymatically active schistosomal hypoxanthine/guanine phosphoribosyltransferase and trypanosomal ornithine decarboxylase.

C. Wang, S. Craig, J. McKerrow, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor.

G. Poda, K. Packman, G. Privé, 2023, ACS medicinal chemistry letters.

Structures of RGL1 RAS-Association domain in complex with KRAS and the oncogenic G12V mutant.

M. Ikura, G. Privé, C. Marshall, 2022, Journal of molecular biology.

A Single Chain Fv Fragment of P-glycoprotein-specific Monoclonal Antibody C219

D. Kuntz, K. Johns, D. Rose, 1997, The Journal of Biological Chemistry.

A long-wavelength fluorescent substrate for continuous fluorometric determination of alpha-mannosidase activity: resorufin alpha-D-mannopyranoside.

J. Naleway, D. Kuntz, D. Rose, 2010, Analytical biochemistry.

The Drosophila GMII gene encodes a Golgi alpha-mannosidase II.

C. Rabouille, D. Kuntz, R. Watson, 1999, Journal of cell science.

Comparison of kifunensine and 1-deoxymannojirimycin binding to class I and II alpha-mannosidases demonstrates different saccharide distortions in inverting and retaining catalytic mechanisms.

D. Kuntz, D. Rose, N. Shah, 2003, Biochemistry.

Human lysosomal α‐mannosidases exhibit different inhibition and metal binding properties

D. Kuntz, D. Rose, M. Venkatesan, 2009, Protein science : a publication of the Protein Society.

Binding of sulfonium‐ion analogues of di‐epi‐swainsonine and 8‐epi‐lentiginosine to Drosophila Golgi α‐mannosidase II: The role of water in inhibitor binding

B. M. Pinto, D. Kuntz, D. Rose, 2007, Proteins.

3321 Drosophila GMII encodes Golgi α-mannosidase II Indirect immunofluorescence microscopy

C. Rabouille, D. Kuntz, R. Watson, 2022 .

Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant.

D. Kuntz, K. Moremen, G. Boons, 2008, Journal of the American Chemical Society.

A Long Wavelength Fluorescent Substrate for Continuous Fluorometric Determination of α -Mannosidase Activity: Resorufin α -D-Mannopyranoside

J. Naleway, D. Kuntz, D. Rose, 2010 .

The translation initiation site of recombinant Trypanosoma brucei ornithine decarboxylase varies with different promoters.

M. Phillips, C. Wang, S. Craig, 1992, Molecular and biochemical parasitology.