J. Meier

发表

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation.

P. Carmeliet, E. Verdin, A. Sickmann, 2018, Cell metabolism.

A systems chemoproteomic analysis of acyl-CoA/protein interaction networks

Mihaela E. Sardiu, M. Washburn, L. Florens, 2019, bioRxiv.

Modulation of NF-κB-dependent gene transcription using programmable DNA minor groove binders

P. Dervan, P. Ramakrishnan, J. Meier, 2011, Proceedings of the National Academy of Sciences.

Guiding the Design of Synthetic DNA-Binding Molecules with Massively Parallel Sequencing

I. Korf, P. Dervan, D. Segal, 2012, Journal of the American Chemical Society.

Expanding the Repertoire of Natural Product-Inspired Ring Pairs for Molecular Recognition of DNA

Katy A. Muzikar, P. Dervan, J. Meier, 2011, Organic letters.

Chemical cryptology of cancer's histone code.

J. Meier, R. Kulkarni, 2014, Chemistry & biology.

Photoinducible Oncometabolite Detection

A. Lane, S. Lockett, T. Fan, 2018, Chembiochem : a European journal of chemical biology.

The unusual macrocycle forming thioesterase of mycolactone.

Timothy L. Foley, J. Meier, M. Burkart, 2008, Molecular bioSystems.

Animal Toxicity of Hairpin Pyrrole-Imidazole Polyamides Varies with the Turn Unit

Jerzy O. Szablowski, P. Dervan, J. Meier, 2013, Journal of medicinal chemistry.

Modular synthesis of cell-permeating 2-ketoglutarate esters.

J. Meier, R. Kulkarni, Thomas T. Zengeya, 2015, Organic letters.

Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase–deficient renal cancer

Mark W. Ball, A. Lane, W. Linehan, 2021, Science Signaling.

Probing small ribosomal subunit RNA helix 45 acetylation across eukaryotic evolution

D. Lafontaine, J. Meier, Justin M. Thomas, 2021, bioRxiv.

Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping

Schraga Schwartz, M. Washburn, L. Florens, 2020, Nature.

Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels*

John M. Viola, K. Wellen, I. Blair, 2017, The Journal of Biological Chemistry.

Chemoproteomic Profiling of Lysine Acetyltransferases Highlights an Expanded Landscape of Catalytic Acetylation

J. Meier, David C. Montgomery, Alexander W. Sorum, 2014, Journal of the American Chemical Society.

Global Profiling of Acetyltransferase Feedback Regulation.

M. Vedadi, Julie M. Garlick, J. Meier, 2016, Journal of the American Chemical Society.

Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species

Erika L. Varner, J. Meier, K. Bedi, 2022, Journal of lipid research.

Statin therapy inhibits fatty acid synthase via dynamic protein modifications

Scott B. Crown, J. Thompson, O. Ilkayeva, 2021, Nature Communications.

Reference compounds for characterizing cellular injury in high-content cellular morphology assays

Anne E Carpenter, Jayme L. Dahlin, Bruce K. Hua, 2022, bioRxiv.

Defining Metabolic and Nonmetabolic Regulation of Histone Acetylation by NSAID Chemotypes.

E. Verdin, Julie M. Garlick, I. Blair, 2017, Molecular pharmaceutics.

Microfluidic Mobility Shift Profiling of Lysine Acetyltransferases Enables Screening and Mechanistic Analysis of Cellular Acetylation Inhibitors.

A. Jadhav, A. Simeonov, J. Meier, 2016, ACS chemical biology.

Antisense pairing and SNORD13 structure guide RNA cytidine acetylation

J. Cavaille, Schraga Schwartz, J. Meier, 2022, bioRxiv.

PI3K drives the de novo synthesis of coenzyme A from vitamin B5

J. Clohessy, A. Toker, L. Cantley, 2022, Nature.

An Oncometabolite Isomer Rapidly Induces A Pathophysiological Protein Modification

W. Linehan, J. Meier, S. Bergholtz, 2020, bioRxiv.

Activity-based profiling in RNA

J. Meier, Supuni Thalalla Gamage, 2021, Nature Chemical Biology.

Bioorthogonal pro-metabolites for profiling short chain fatty acylation† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc00247e

Julie M. Garlick, I. Blair, J. Meier, 2016, bioRxiv.

Bioorthogonal pro-metabolites for profiling short chain fatty acylation

Julie M. Garlick, I. Blair, J. Meier, 2016, bioRxiv.

Conditional covalent lethality driven by oncometabolite accumulation

W. Linehan, J. Meier, E. Weerapana, 2022, bioRxiv.

Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity

E. Verdin, M. Ott, J. Maksimoska, 2016, eLife.

Probing the Compatibility of Type II Ketosynthase–Carrier Protein Partners

B. Moore, J. Meier, M. Burkart, 2008, Chembiochem : a European journal of chemical biology.

Fluorescent profiling of modular biosynthetic enzymes by complementary metabolic and activity based probes.

J. Meier, M. Burkart, A. Mercer, 2008, Journal of the American Chemical Society.

Chemoproteomics yields a selective molecular host for acetyl-CoA

Z. A. Brown, J. Meier, Carissa Grose, 2022, bioRxiv.

High-throughput single-molecule screen for small-molecule perturbation of splicing and transcription kinetics.

A. Coulon, D. Larson, Christopher R. Day, 2016, Methods.

A chemoproteomic portrait of the oncometabolite fumarate

W. Linehan, M. Washburn, L. Florens, 2018, bioRxiv.

Metabolic mechanisms of epigenetic regulation.

J. Meier, 2013, ACS chemical biology.

The chemical biology of modular biosynthetic enzymes.

Michael D Burkart, J. Meier, M. Burkart, 2009, Chemical Society reviews.

Design of Sequence-Specific DNA Binding Molecules for DNA Methyltransferase Inhibition

P. Dervan, J. Meier, JeenJoo S. Kang, 2014, Journal of the American Chemical Society.

Pyrrole-imidazole polyamides distinguish between double-helical DNA and RNA.

P. Dervan, J. Meier, D. Chenoweth, 2013, Angewandte Chemie.

Enhancing the cellular uptake of Py–Im polyamides through next-generation aryl turns

P. Dervan, J. Meier, David C. Montgomery, 2012, Nucleic acids research.

Crosslinking studies of protein-protein interactions in nonribosomal peptide biosynthesis.

M. Marahiel, C. Bertozzi, Julian A. Codelli, 2009, Chemistry & biology.

The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis.

V. Nizet, E. Strauss, J. Meier, 2012, Chemistry & biology.

Chapter 9. Synthetic probes for polyketide and nonribosomal peptide biosynthetic enzymes.

J. Meier, M. Burkart, 2009, Methods in enzymology.

Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification.

J. Meier, M. Burkart, Heriberto Rivera, 2006, Journal of the American Chemical Society.

Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling.

W. Linehan, A. Weissman, Julie M. Garlick, 2017, Cell chemical biology.

An orthogonal active site identification system (OASIS) for proteomic profiling of natural product biosynthesis.

Timothy L. Foley, Sherry L. Niessen, Heather S Hoover, 2009, ACS chemical biology.

Acetylation of Cytidine in mRNA Promotes Translation Efficiency

David Sturgill, Kyster K. Nanan, Thorkell Andresson, 2018, Cell.

Metabolic Regulation of the Epitranscriptome.

Pedro J. Batista, J. Meier, Justin M. Thomas, 2019, ACS chemical biology.

Profiling Cytidine Acetylation with Specific Affinity and Reactivity.

Thorkell Andresson, Shalini Oberdoerffer, J. Meier, 2017, ACS chemical biology.

Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues

Erika L. Varner, K. Wellen, J. Meier, 2020, Open Biology.

Nucleotide resolution sequencing of N4-acetylcytidine in RNA.

J. Meier, Justin M. Thomas, Keri Bryson, 2019, Methods in enzymology.

A Chemical Signature for Cytidine Acetylation in RNA.

Aldema Sas-Chen, Thorkell Andresson, Kellie D Nance, 2018, Journal of the American Chemical Society.

Harnessing Ionic Selectivity In Acetyltransferase Chemoproteomic Probes

M. Washburn, L. Florens, P. Kung, 2020 .

Mapping Lysine Acetyltransferase-Ligand Interactions by Activity-Based Capture.

J. Meier, David C. Montgomery, D. C. Montgomery, 2016, Methods in enzymology.

Metabolic Regulation of Histone Acetyltransferases by Endogenous Acyl-CoA Cofactors.

M. Nicklaus, J. Meier, L. Guasch, 2015, Chemistry & biology.

Modifications in an Emergency: The Role of N1-Methylpseudouridine in COVID-19 Vaccines

J. Meier, Kellie D. Nance, 2021, ACS central science.

A systems chemoproteomic analysis of acyl-CoA/protein interaction networks

Mihaela E. Sardiu, M. Washburn, L. Florens, 2019, bioRxiv.

Arrow pushing in RNA modification sequencing.

J. Meier, David Bartee, Supuni Thalalla Gamage, 2021, Chemical Society reviews.

Protonation-Dependent Sequencing of 5-Formylcytidine in RNA.

H. Prokisch, R. Chari, J. Ivanic, 2022, Biochemistry.

Site-Specific Synthesis of N4-Acetylcytidine in RNA Reveals Physiological Duplex Stabilization.

J. Meier, Kellie D. Nance, David Bartee, 2022, Journal of the American Chemical Society.

Cytidine acetylation yields a hypoinflammatory synthetic messenger RNA.

M. Washburn, L. Florens, Shuo Gu, 2021, Cell chemical biology.

Protonation-Dependent Sequencing of 5-Formylcytidine in RNA

H. Prokisch, R. Chari, J. Ivanic, 2021, bioRxiv.

Site-Specific Synthesis of N4-Acetylcytidine in RNA Reveals Physiological Duplex Stabilization

J. Meier, Kellie D. Nance, David Bartee, 2021, bioRxiv.

Quantitative nucleotide resolution profiling of RNA cytidine acetylation by ac4C-seq

Schraga Schwartz, J. Meier, A. Sas-Chen, 2021, Nature Protocols.

Remodelin Is a Cryptic Assay Interference Chemotype That Does Not Inhibit NAT10-Dependent Cytidine Acetylation.

Jayme L. Dahlin, M. Walters, D. Lafontaine, 2020, ACS medicinal chemistry letters.

Visualizing RNA Cytidine Acetyltransferase Activity by Northern Blotting

J. Meier, Keri Bryson, Supuni Thalalla-Gamage, 2020, Current protocols in chemical biology.

Characterization of Specific N-α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.

W. K. Sonnenburg, P. Kung, Sergei L Timofeevski, 2020, ACS medicinal chemistry letters.

Epigenetic regulation by endogenous metabolite pharmacology.

J. Meier, R. Kulkarni, David C. Montgomery, 2019, Current opinion in chemical biology.

Chemical control of a CRISPR-Cas9 acetyltransferase

A. Jadhav, J. Meier, Jonathan H. Shrimp, 2017, bioRxiv.

Characterization and Solubilization of Pyrrole–Imidazole Polyamide Aggregates

P. Dervan, J. Meier, A. Hargrove, 2012, Journal of medicinal chemistry.

Quantification of lactoyl-CoA by liquid chromatography mass spectrometry in mammalian cells and tissues

Erika L. Varner, K. Wellen, J. Meier, 2020, bioRxiv.

Quantitative prospective and retrospective mass spectrometry of lactoyl-CoA in mammalian cells and tissues

Erika L. Varner, K. Wellen, J. Meier, 2020 .

Defining the Orphan Functions of Lysine Acetyltransferases

J. Meier, David C. Montgomery, Alexander W. Sorum, 2015, ACS chemical biology.

Synthesis and Evaluation of a Stable Isostere of Malonyllysine

J. Meier, R. Kulkarni, S. Bergholtz, 2020, bioRxiv.

Practical 4'-phosphopantetheine active site discovery from proteomic samples.

V. Bafna, P. Dorrestein, B. Cravatt, 2011, Journal of proteome research.

A chemically stable fluorescent marker of the ureter.

J. Cha, J. Meier, R. Kulkarni, 2018, Bioorganic & medicinal chemistry letters.

In Vivo Modification of Native Carrier Protein Domains

J. Meier, M. Burkart, J. Torpey, 2009, Chembiochem : a European journal of chemical biology.

Structural and Biochemical Analysis of Protein-Protein Interactions Between the Acyl-Carrier Protein and Product Template Domain.

C. Townsend, J. Meier, M. Burkart, 2016, Angewandte Chemie.

A mechanism based protein crosslinker for acyl carrier protein dehydratases.

J. Meier, M. Burkart, R. Haushalter, 2010, Bioorganic & medicinal chemistry letters.

Molecular basis of antibiotic multiresistance transfer in Staphylococcus aureus

L. Betts, P. Dervan, M. Redinbo, 2013, Proceedings of the National Academy of Sciences.

Target 2035 – update on the quest for a probe for every protein

G. A. Bezerra, T. Willson, G. Superti-Furga, 2021, RSC medicinal chemistry.

Title Salicylate , diflunisal and their metabolites inhibit CBP / p 300 and exhibit anticancer activity

E. Verdin, M. Ott, J. Maksimoska, 2019 .

Learning the metabolic language of cancer

J. Meier, Minervo Perez, 2023, Nature.

New insights into the pathophysiology of methylmalonic acidemia

C. Venditti, J. Meier, PamelaSara E. Head, 2023, Journal of inherited metabolic disease.

Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors

Jayme L. Dahlin, J. Baell, M. Walters, 2017, Nature Communications.

Comparative analysis of drug-like EP300/CREBBP acetyltransferase inhibitors

A. Simeonov, N. Coussens, Stephen C. Kales, 2023, bioRxiv.

Characterizing the Covalent Targets of a Small Molecule Inhibitor of the Lysine Acetyltransferase P300.

Julie M. Garlick, M. Nicklaus, J. Meier, 2016, ACS medicinal chemistry letters.

Rewiring of RNA methylation by the oncometabolite fumarate in renal cell carcinoma

Pedro J. Batista, W. Linehan, L. Jenkins, 2023, bioRxiv.

Co-opting a Bioorthogonal Reaction for Oncometabolite Detection.

W. Linehan, Julie M. Garlick, Youfeng Yang, 2016, Journal of the American Chemical Society.

Bioorthogonal oncometabolite ligation.

J. Meier, Chloe A. Briney, Susana S. Najera, 2019, Methods in enzymology.

Metabolic regulation of epigenetic drug resistance

J. Meier, N. Snyder, 2023, Nature chemical biology.

Chemical control of multidomain acetyltransferase activity.

J. Meier, Yihang Jing, Whitney K. Lieberman, 2021, Cell Chemical Biology.

Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite

W. Linehan, Youfeng Yang, J. Meier, 2020, The Journal of Biological Chemistry.

Harnessing Ionic Selectivity In Acetyltransferase Chemoproteomic Probes

M. Washburn, L. Florens, P. Kung, 2020, bioRxiv.

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation.

P. Carmeliet, E. Verdin, A. Sickmann, 2018, Cell metabolism.

Comparative Analysis of Drug-like EP300/CREBBP Acetyltransferase Inhibitors.

A. Simeonov, N. Coussens, Stephen C. Kales, 2023, ACS chemical biology.

Remodelin Is a Cryptic Assay Interference Chemotype That Does Not Inhibit NAT10-Dependent Cytidine Acetylation.

Jayme L. Dahlin, M. Walters, D. Lafontaine, 2020, ACS medicinal chemistry letters.

Chemical Control of a CRISPR-Cas9 Acetyltransferase.

A. Jadhav, J. Meier, Abigail L. Thorpe, 2018, ACS chemical biology.

Profiling Cytidine Acetylation with Specific Affinity and Reactivity.

Shalini Oberdoerffer, J. Meier, S. Fox, 2017, ACS chemical biology.

Characterization of Specific N-α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.

W. K. Sonnenburg, P. Kung, M. Gehring, 2020, ACS medicinal chemistry letters.