J. J. Zhang

发表

Crystal Structure of Oligomeric β1-Adrenergic G Protein- Coupled Receptors in Ligand-Free Basal State

Jianyun Huang, Xin-Yun Huang, Jianyun Huang, 2013, Nature Structural &Molecular Biology.

Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling.

J. Darnell, W. Gu, U. Vinkemeier, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Migrastatin Analogues Target Fascin to Block Tumor Metastasis

Xin-Yun Huang, J. J. Zhang, J. Jakoncic, 2010, Nature.

Anti-Metastasis Fascin Inhibitors Decrease the Growth of Specific Subtypes of Cancers

Xin-Yun Huang, J. J. Zhang, Yufeng Wang, 2020, Cancers.

Improving fascin inhibitors to block tumor cell migration and metastasis

C. Reinhart-King, Bowen Xing, Xin-Yun Huang, 2016, Molecular oncology.

Mouse models for tumor metastasis.

Xin-Yun Huang, J. J. Zhang, Shengyu Yang, 2012, Methods in molecular biology.

Dosage‐dependent switch from G protein‐coupled to G protein‐independent signaling by a GPCR

B. Kobilka, Xin-Yun Huang, H. Jüppner, 2007, The EMBO journal.

G-Protein Gα13 Functions with Abl Kinase to Regulate Actin Cytoskeletal Reorganization.

Bowen Xing, Xin-Yun Huang, Jianyun Huang, 2017, Journal of molecular biology.

Atypical Protein Kinase Cλ Is Critical for Growth Factor Receptor-induced Dorsal Ruffle Turnover and Cell Migration*

Bowen Xing, Xin-Yun Huang, Jianyun Huang, 2013, The Journal of Biological Chemistry.

Resistance to Inhibitors of Cholinesterase-8A (Ric-8A) Is Critical for Growth Factor Receptor-induced Actin Cytoskeletal Reorganization*

H. Shu, Bowen Xing, Xin-Yun Huang, 2011, The Journal of Biological Chemistry.

Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation.

B. Chait, J. Darnell, W. W. Lathem, 1998, The EMBO journal.

Stimulation of guanylyl cyclase-D by bicarbonate.

Xin-Yun Huang, J. J. Zhang, D. Guo, 2009, Biochemistry.

C-terminal Src Kinase (Csk)-mediated Phosphorylation of Eukaryotic Elongation Factor 2 (eEF2) Promotes Proteolytic Cleavage and Nuclear Translocation of eEF2*

Bowen Xing, Xin-Yun Huang, J. J. Zhang, 2014, The Journal of Biological Chemistry.

Orai1 and STIM1 are critical for breast tumor cell migration and metastasis.

Xin-Yun Huang, J. J. Zhang, Shengyu Yang, 2009, Cancer cell.

Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity

Xiaojing Ma, Ming O. Li, Xin-Yun Huang, 2021, Cell reports.

Migrastatin analogues target fascin to block tumour metastasis

Jean Jakoncic, Shengyu Yang, Xin-Yun Huang, 2011, Nature.

Critical Roles of STAT3 in &bgr;-Adrenergic Functions in the Heart

Y. Liu, Xin-Yuan Fu, M. Rubart, 2016, Circulation.

Pivotal Role of Extended Linker 2 in the Activation of Gα by G Protein-coupled Receptor*

Xin-Yun Huang, Jianyun Huang, J. J. Zhang, 2014, The Journal of Biological Chemistry.

Targeted inhibition of fascin function blocks tumour invasion and metastatic colonization

C. Reinhart-King, Bowen Xing, Xin-Yun Huang, 2015, Nature Communications.

Distinct Transcriptional Activation Functions of STAT1α and STAT1β on DNA and Chromatin Templates*

J. Darnell, E. Yang, N. Zakharova, 2003, Journal of Biological Chemistry.

Stat3 is essential for neuronal differentiation through direct transcriptional regulation of the Sox6 gene

Xin-Yun Huang, J. J. Zhang, M. Snyder, 2011, FEBS letters.

'Tuning' of type I interferon–induced Jak-STAT1 signaling by calcium-dependent kinases in macrophages

R. Baron, J. Schlessinger, L. Ivashkiv, 2008, Nature Immunology.

Identification of Novel Direct Stat3 Target Genes for Control of Growth and Differentiation*

Xin-Yun Huang, J. J. Zhang, M. Snyder, 2008, Journal of Biological Chemistry.

A Signal Transducer and Activator of Transcription 3·Nuclear Factor κB (Stat3·NFκB) Complex Is Necessary for the Expression of Fascin in Metastatic Breast Cancer Cells in Response to Interleukin (IL)-6 and Tumor Necrosis Factor (TNF)-α*

Xin-Yun Huang, Jianyun Huang, J. J. Zhang, 2014, The Journal of Biological Chemistry.

Signal Transducers and Activators of Transcription 3 (STAT3) Directly Regulates Cytokine-induced Fascin Expression and Is Required for Breast Cancer Cell Migration*

Xin-Yun Huang, J. J. Zhang, Xin-Yun Huang, 2011, The Journal of Biological Chemistry.

Stat3 Directly Controls the Expression of Tbx5, Nkx2.5, and GATA4 and Is Essential for Cardiomyocyte Differentiation of P19CL6 Cells*

Xin-Yun Huang, J. J. Zhang, M. Snyder, 2010, The Journal of Biological Chemistry.

Regulation of Stat3 transcriptional activity by the conserved LPMSP motif for OSM and IL‐6 signaling

D. Levy, J. J. Zhang, M. Snyder, 2006, FEBS letters.

Stat1-Dependent Synergistic Activation of T-bet for IgG2a Production during Early Stage of B Cell Activation1

J. J. Zhang, Weifeng Xu, J. J. Zhang, 2005, The Journal of Immunology.

The DNA replication factor MCM5 is essential for Stat1-mediated transcriptional activation.

Wei He, J. J. Zhang, M. Snyder, 2005, Proceedings of the National Academy of Sciences of the United States of America.

B cell antigen receptor signaling enhances IFN-gamma-induced Stat1 target gene expression through calcium mobilization and activation of multiple serine kinase pathways.

J. Nair, J. J. Zhang, Weifeng Xu, 2005, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-γ

J. J. Zhang, C J DaFonseca, F Shu, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Critical Roles of STAT 3 in-Adrenergic Functions in the Heart Running title : Zhang et al . ; STAT 3 and-Adrenergic Signaling

Y. Liu, Xin-Yuan Fu, M. Rubart, 2015 .

Distinct transcriptional activation functions of STAT1alpha and STAT1beta on DNA and chromatin templates.

J. Darnell, E. Yang, N. Zakharova, 2003, The Journal of biological chemistry.

Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-γ

B. Chait, J. Darnell, J. Nair, 2002, Proceedings of the National Academy of Sciences of the United States of America.

The Minichromosome Maintenance Proteins 2-7 (MCM2-7) Are Necessary for RNA Polymerase II (Pol II)-mediated Transcription*

Xin-Yun Huang, J. J. Zhang, M. Snyder, 2009, Journal of Biological Chemistry.

Molecular Mechanism of Fascin Function in Filopodial Formation*

R. Diaz-Avalos, Xin-Yun Huang, Jianyun Huang, 2012, The Journal of Biological Chemistry.

The Conserved Leu-724 Residue Is Required for Both Serine Phosphorylation and Co-activator Recruitment for Stat1-mediated Transcription Activation in Response to Interferon-γ*

L. Ivashkiv, Wei He, J. J. Zhang, 2005, Journal of Biological Chemistry.

cAMP Inhibits Cell Migration by Interfering with Rac-induced Lamellipodium Formation*

Lin Chen, Xin-Yun Huang, J. J. Zhang, 2008, Journal of Biological Chemistry.

A new Rac/PAK/GC/cGMP signaling pathway

Xin-Yun Huang, J. J. Zhang, D. Guo, 2009, Molecular and Cellular Biochemistry.

Fascin Inhibitors Decrease Cell Migration and Adhesion While Increase Overall Survival of Mice Bearing Bladder Cancers

Xin-Yun Huang, J. J. Zhang, Yufeng Wang, 2021, Cancers.

Suppression of Tumor Angiogenesis by Gα13 Haploinsufficiency*

S. Rafii, Xin-Yun Huang, J. J. Zhang, 2009, The Journal of Biological Chemistry.

A Rac-cGMP Signaling Pathway

Yi Zheng, Xin-Yun Huang, J. J. Zhang, 2007, Cell.

Huang et al . 1 Pivotal Role of Extended Linker 2 in the Activation of G α by G Protein-Coupled Receptor

Xin-Yun Huang, Jianyun Huang, J. J. Zhang, 2014 .