Guoxun Zheng

发表

What Contributes to Serotonin-Norepinephrine Reuptake Inhibitors' Dual-Targeting Mechanism? The Key Role of Transmembrane Domain 6 in Human Serotonin and Norepinephrine Transporters Revealed by Molecular Dynamics Simulation.

Yuzong Chen, X. Yao, Weiwei Xue, 2018, ACS chemical neuroscience.

The binding mode of vilazodone in the human serotonin transporter elucidated by ligand docking and molecular dynamics simulations.

X. Yao, Weiwei Xue, Guoxun Zheng, 2020, Physical chemistry chemical physics : PCCP.

Exploring the Inhibitory Mechanism of Approved Selective Norepinephrine Reuptake Inhibitors and Reboxetine Enantiomers by Molecular Dynamics Study

Feng Zhu, Weiwei Xue, Xiaojun Yao, 2016, Scientific Reports.

Differentiating physicochemical properties between NDRIs and sNRIs clinically important for the treatment of ADHD.

Feng Zhu, Weiwei Xue, Xiaojun Yao, 2017, Biochimica et biophysica acta. General subjects.

Revealing vilazodone's binding mechanism underlying its partial agonism to the 5-HT1A receptor in the treatment of major depressive disorder.

Feng Zhu, Weiwei Xue, Xiaojun Yao, 2017, Physical chemistry chemical physics : PCCP.

Computational characterization of the selective inhibition of human norepinephrine and serotonin transporters by an escitalopram scaffold.

Feng Zhu, Weiwei Xue, Xiaojun Yao, 2018, Physical chemistry chemical physics : PCCP.

Recent Advances and Challenges of the Drugs Acting on Monoamine Transporters.

Feng Zhu, Yang Zhang, Weiwei Xue, 2018, Current medicinal chemistry.

How Does Chirality Determine the Selective Inhibition of Histone Deacetylase 6? A Lesson from Trichostatin A Enantiomers Based on Molecular Dynamics.

Feng Zhu, Yunqing Qiu, Yan Lou, 2019, ACS chemical neuroscience.

Comparison of computational model and X-ray crystal structure of human serotonin transporter: potential application for the pharmacology of human monoamine transporters

Feng Zhu, Weiwei Xue, Xiaojun Yao, 2017 .

Selective Inhibition of HDAC1 by Macrocyclic Polypeptide for the Treatment of Glioblastoma: A Binding Mechanistic Analysis Based on Molecular Dynamics

X. Yao, Weiwei Xue, Guoxun Zheng, 2020, Frontiers in Molecular Biosciences.

Subtype-selective mechanisms of negative allosteric modulators binding to group I metabotropic glutamate receptors

X. Yao, Weiwei Xue, Fengyuan Yang, 2020, Acta pharmacologica Sinica.

Computational identification of the binding mechanism of a triple reuptake inhibitor amitifadine for the treatment of major depressive disorder.

Feng Zhu, Weiwei Xue, Xiaojun Yao, 2018, Physical chemistry chemical physics : PCCP.

Exploring the Binding Mechanism of Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators in Clinical Trials by Molecular Dynamics Simulations.

Feng Zhu, Weiwei Xue, Xiaojun Yao, 2018, ACS chemical neuroscience.

Prediction of the binding mode and resistance profile for a dual-target pyrrolyl diketo acid scaffold against HIV-1 integrase and reverse-transcriptase-associated ribonuclease H.

Feng Zhu, Weiwei Xue, Xiaojun Yao, 2018, Physical chemistry chemical physics : PCCP.

Follistatin-like 1 (FSTL1) interacts with Wnt ligands and Frizzled receptors to enhance Wnt/β-catenin signaling in obstructed kidneys in vivo

Youhua Liu, C. Dai, Guoxun Zheng, 2022, The Journal of biological chemistry.

Targeting PI4KA sensitizes refractory leukemia to chemotherapy by modulating the ERK/AMPK/OXPHOS axis

Guoxun Zheng, Shuangnian Xu, Xiang-tao Huang, 2022, Theranostics.

Computational Chemistry in Structure-Based Solute Carrier Transporter Drug Design: Recent Advances and Future Perspectives

Weiwei Xue, Guoxun Zheng, Gao Tu, 2024, J. Chem. Inf. Model..

What Contributes to Serotonin-Norepinephrine Reuptake Inhibitors' Dual-Targeting Mechanism? The Key Role of Transmembrane Domain 6 in Human Serotonin and Norepinephrine Transporters Revealed by Molecular Dynamics Simulation.

Yuzong Chen, X. Yao, Weiwei Xue, 2018, ACS chemical neuroscience.

Computational identification of the binding mechanism of a triple reuptake inhibitor amitifadine for the treatment of major depressive disorder.

Yuzong Chen, X. Yao, Weiwei Xue, 2018, Physical chemistry chemical physics : PCCP.

Rational Remodeling of Atypical Scaffolds for the Design of Photoswitchable Cannabinoid Receptor Tools.

R. Stevens, Guisheng Zhong, Suwen Zhao, 2021, Journal of medicinal chemistry.