A. Sleigh

发表

Defective Mitochondrial Function In Vivo in Skeletal Muscle in Adults with Down’s Syndrome: A 31P-MRS Study

G. Kemp, S. Brage, A. Holland, 2013, PloS one.

Lipodystrophy: metabolic insights from a rare disorder.

S. O’Rahilly, D. Savage, A. Sleigh, 2010, The Journal of endocrinology.

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis.

S. O’Rahilly, D. Lomas, P. Murgatroyd, 2009, The Journal of clinical investigation.

Low circulating levels of IGF-1 in healthy adults are associated with reduced β-cell function, increased intramyocellular lipid, and enhanced fat utilization during fasting.

D. Dunger, A. Vaag, G. Yeo, 2014, The Journal of clinical endocrinology and metabolism.

Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals

C. Cooper, S. Sharp, N. Wareham, 2013, International journal of endocrinology.

Accumulation of saturated intramyocellular lipid is associated with insulin resistance[S]

C. Boesch, G. Kemp, S. Brage, 2019, Journal of Lipid Research.

Magnetic resonance spectroscopy analysis of intramyocellular lipid composition in lipodystrophic patients and athletes

C. Boesch, G. Kemp, S. Brage, 2018, bioRxiv.

Compositional marker in vivo reveals intramyocellular lipid turnover during fasting-induced lipolysis

D. Dunger, C. Boesch, G. Kemp, 2018, Scientific Reports.

Constitutive Activation of AKT2 in Humans Leads to Hypoglycemia Without Fatty Liver or Metabolic Dyslipidemia

S. O’Rahilly, N. Wareham, Julie Harris, 2017, The Journal of clinical endocrinology and metabolism.

Metabolic and cellular phenotype of AKT 2 hyperactiva on Constitutive activation of AKT 2 in humans leads to hypoglycemia without fatty liver or metabolic dyslipidemia

S. O’Rahilly, N. Wareham, Julie Harris, 2017 .

31P magnetization transfer measurements of Pi→ATP flux in exercising human muscle

Guy B. Williams, G. Kemp, K. Brindle, 2016, Journal of applied physiology.

Familial adult onset hyperinsulinism due to an activating glucokinase mutation: implications for pharmacological glucokinase activation

Julie Harris, K. Dhatariya, A. Sleigh, 2014, Clinical endocrinology.

31P magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations

C. Boesch, G. Kemp, A. Heerschap, 2020, NMR in biomedicine.

Effect of Iron Isomaltoside on Skeletal Muscle Energetics in Patients With Chronic Heart Failure and Iron Deficiency.

G. Kemp, A. Shah, G. Charles-Edwards, 2019, Circulation.

Accumulation of saturated intramyocellular lipid is associated with insulin resistance patient-oriented and epidemiological research

C. Boesch, S. Brage, D. Savage, 2019 .

P magnetization transfer measurements of Pi-> ATP flux in exercising human muscle 1 2

Guy B. Williams, G. Kemp, K. Brindle, 2015 .

31 P magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations Muscle

C. Boesch, A. Heerschap, H. Reyngoudt, 2020 .

Truncation of POC1A associated with short stature and extreme insulin resistance.

M. Segni, S. O’Rahilly, I. Barroso, 2015, Journal of molecular endocrinology.

Intramyocellular lipid levels are associated with peripheral, but not hepatic, insulin sensitivity in normal healthy subjects.

D. Dunger, P. Murgatroyd, A. Sleigh, 2009, Clinical science.

Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations

S. O’Rahilly, M. Dattani, I. Barroso, 2016, JCI insight.

Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression

T. Hansen, O. Pedersen, S. O’Rahilly, 2017, eLife.

Mutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease

S. O’Rahilly, Yali Xue, V. Saudek, 2014, Proceedings of the National Academy of Sciences.

Validation of Ultrasound Estimates of Visceral Fat in Black South African Adolescents

D. Dunger, S. Norris, S. Brage, 2011, Obesity.

Ultrasound Measurements of Visceral and Subcutaneous Abdominal Thickness to Predict Abdominal Adiposity Among Older Men and Women

C. Cooper, S. Sharp, N. Wareham, 2010, Obesity.

Lipodystrophy: A paradigm for understanding the consequences of "overloading" adipose tissue.

D. Savage, A. Sleigh, C. Adams, 2020, Physiological reviews.

The metabolic syndrome- associated small G protein ARL15 plays a role in adipocyte differentiation and adiponectin secretion

S. O’Rahilly, V. Saudek, I. Barroso, 2017, Scientific Reports.

Randomized controlled trial of the efficacy of aerobic exercise in reducing metabolic risk in healthy older people: The Hertfordshire Physical Activity Trial

U. Ekelund, C. Cooper, S. Sharp, 2009, BMC endocrine disorders.

Simple and effective exercise design for assessing in vivo mitochondrial function in clinical applications using 31P magnetic resonance spectroscopy

D. Dunger, V. Lupson, D. Savage, 2016, Scientific Reports.

Abdominal fat depots associated with insulin resistance and metabolic syndrome risk factors in black African young adults

D. Dunger, S. Norris, K. Ong, 2015, BMC Public Health.

Computed tomography-based validation of abdominal adiposity measurements from ultrasonography, dual-energy X-ray absorptiometry and anthropometry.

S. Brage, P. Franks, P. Nordström, 2010, The British journal of nutrition.

Validity of visceral adiposity estimates from DXA against MRI in Kuwaiti men and women

T. Kivisild, N. Wareham, S. Brage, 2017, Nutrition & diabetes.

Assessing Metabolism and Injury in Acute Human Traumatic Brain Injury with Magnetic Resonance Spectroscopy: Current and Future Applications

T. Carpenter, A. Sleigh, K. Carpenter, 2017, Front. Neurol..

Dyslipidemia, Insulin Resistance, Ectopic Lipid Accumulation, and Vascular Function in Resistance to Thyroid Hormone β

C. McEniery, K. Burling, A. Sleigh, 2021, Journal of Clinical Endocrinology and Metabolism.

Mitochondrial dysfunction in patients with primary congenital insulin resistance.

S. O’Rahilly, G. Kemp, S. Brage, 2011, The Journal of clinical investigation.

Validity of ultrasonography to assess hepatic steatosis compared to magnetic resonance spectroscopy as a criterion method in older adults

N. Wareham, S. Brage, K. Ong, 2018, PloS one.

Short-term administration of pegvisomant improves hepatic insulin sensitivity and reduces soleus muscle intramyocellular lipid content in young adults with type 1 diabetes.

D. Dunger, D. Elleri, C. Acerini, 2014, The Journal of clinical endocrinology and metabolism.

The effects of aerobic exercise on metabolic risk, insulin sensitivity and intrahepatic lipid in healthy older people from the Hertfordshire Cohort Study: a randomised controlled trial

U. Ekelund, S. Sharp, S. Brage, 2010, Diabetologia.

Corrigendum: Assessing Metabolism and Injury in Acute Human Traumatic Brain Injury with Magnetic Resonance Spectroscopy: Current and Future Applications

T. Adrian Carpenter, T. Carpenter, A. Sleigh, 2017, Front. Neurol..

Liver fat accumulation is associated with reduced hepatic insulin extraction and beta cell dysfunction in healthy older individuals

C. Cooper, S. Sharp, N. Wareham, 2014, Diabetology & Metabolic Syndrome.

Mitochondrial Oxidative Phosphorylation Is Impaired in Patients with Congenital Lipodystrophy

Soren Brage, Peter R. Murgatroyd, S. O’Rahilly, 2012, The Journal of clinical endocrinology and metabolism.

The metabolic syndrome- associated small G protein ARL15 plays a role in adipocyte differentiation and adiponectin secretion

S. O’Rahilly, V. Saudek, I. Barroso, 2017, Scientific Reports.

Monitoring metabolism and injury in acute human traumatic brain injury with magnetic resonance spectroscopy: current and future applications

A. Sleigh, K. Carpenter, P. Hutchinson, 2022 .

Truncation of POC1A associated with short stature and extreme insulin resistance.

M. Segni, S. O’Rahilly, I. Barroso, 2015, Journal of molecular endocrinology.