R. Pedrosa

发表

Persistence of the benefit of an antioxidant therapy in children and teenagers with Down syndrome.

E. B. Parisotto, A. Zamoner, T. S. Fröde, 2015, Research in developmental disabilities.

Covalently Bonded N-Acetylcysteine-polyester Loaded in PCL Scaffolds for Enhanced Interactions with Fibroblasts.

R. Pedrosa, C. Sayer, J. M. Beltrame, 2021, ACS applied bio materials.

Risk assessment of a coastal lacustrine environment using oxidative stress biomarkers present in the digestive gland of the Brazilian clam Anomalocardia brasiliana.

E. B. Parisotto, A. Zamoner, R. Pedrosa, 2018 .

Time-Course Variations of DNA Damage and Biomarkers of Oxidative Stress in Tilapia (Oreochromis niloticus) Exposed to Effluents From a Swine Industry

R. Pedrosa, D. Wilhelm Filho, P. L. Lima, 2006, Archives of environmental contamination and toxicology.

In vivo inhibition of tumor progression by 5 hydroxy-1,4-naphthoquinone (juglone) and 2-(4-hydroxyanilino)-1,4-naphthoquinone (Q7) in combination with ascorbate.

J. Benites, P. Calderon, R. Pedrosa, 2016, Biochemical and biophysical research communications.

Inhibition of tumor proliferation associated with cell cycle arrest caused by extract and fraction from Casearia sylvestris (Salicaceae).

R. Pedrosa, K. Felipe, M. Farias, 2014, Journal of ethnopharmacology.

In situ modulation of oxidative stress: a novel and efficient strategy to kill cancer cells.

J. Verrax, P. Calderon, N. Dejeans, 2009, Current medicinal chemistry.

Efficacy assessment of acid mine drainage treatment with coal mining waste using Allium cepa L. as a bioindicator.

R. Pedrosa, V. T. de Fávere, D. Wilhelm-Filho, 2012, Ecotoxicology and environmental safety.

Dietary Patterns and Empirical Dietary Inflammatory Index in Southern Brazil and Risk of Colorectal Cancer: A Case-Control Study

R. Pedrosa, A. W. Zibetti, K. Felipe, 2020, Food and Nutrition Sciences.

Biological Evaluation of 3-Acyl-2-Arylamino-1,4-Naphthoquinones as Inhibitors of Hsp90 Chaperoning Function

J. Benites, J. Verrax, P. Calderon, 2012 .

Biological evaluation of 3-acyl-2-arylamino-1,4-naphthoquinones as inhibitors of Hsp90 chaperoning function.

J. Benites, J. Verrax, R. Pedrosa, 2012, Current topics in medicinal chemistry.

A comparative study of albendazole and mebendazole-induced, time-dependent oxidative stress

A. D. de Bem, R. Pedrosa, T. Creczynski-Pasa, 2004, Redox report : communications in free radical research.

Biological evaluation of donor-acceptor aminonaphthoquinones as antitumor agents.

J. Benites, J. Verrax, P. Calderon, 2010, European journal of medicinal chemistry.

Antiproliferative effects of phenylaminonaphthoquinones are increased by ascorbate and associated with the appearance of a senescent phenotype in human bladder cancer cells.

C. Glorieux, J. Verrax, B. Sid, 2013, Biochemical and biophysical research communications.

Textile Effluents Induce Biomarkers of Acute Toxicity, Oxidative Stress, and Genotoxicity

R. Pedrosa, V. Fávere, D. Wilhelm Filho, 2009, Archives of environmental contamination and toxicology.

Evaluation of Remediation of Coal Mining Wastewater by Chitosan Microspheres Using Biomarkers

R. Pedrosa, V. Fávere, M. Laranjeira, 2006, Archives of environmental contamination and toxicology.

Antioxidant supplementation attenuates oxidative stress in chronic hepatitis C patients.

J. Dias, E. M. Dalmarco, E. B. Parisotto, 2012, Gastroenterologia y hepatologia.

Potent hepatoprotective effect in CCl4-induced hepatic injury in mice of phloroacetophenone from Myrcia multiflora

R. Pedrosa, D. Wilhelm Filho, E. Cargnin-Ferreira, 2010, The Libyan journal of medicine.

Stilbenes and tyrosol as target compounds in the assessment of antioxidant and hypolipidemic activity of Vitis vinifera red wines from southern Brazil.

M. Bordignon-Luiz, R. Pedrosa, D. W. Filho, 2011, Journal of agricultural and food chemistry.

Cytoprotective effects of carvedilol against oxygen free radical generation in rat liver

R. Pedrosa, D. W. Filho, R. Pedrosa, 2005, Redox report : communications in free radical research.

Bioaccumulation and adverse effects of trace metals and polycyclic aromatic hydrocarbons in the common onion Allium cepa as a model in ecotoxicological bioassays

R. Pedrosa, D. Fattorini, V. T. de Fávere, 2011 .

Antioxidant and hepatoprotective effects of Cyathea phalerata Mart. (Cyatheaceae).

R. Pedrosa, M. A. Hort, M. Pizzolatti, 2008, Basic & clinical pharmacology & toxicology.

USE OF COAL MINING WASTE FOR THE REMOVAL OF ACIDITY AND METAL IONS AL (III), FE (III) AND MN (II) IN ACID MINE DRAINAGE

R. Pedrosa, M. Laranjeira, R. Laus, 2008, Environmental technology.

Antioxidant intervention attenuates oxidative stress in children and teenagers with Down syndrome.

E. B. Parisotto, A. Zamoner, T. S. Fröde, 2014, Research in developmental disabilities.

Lipid lowering activity of hydrosoluble chitosan and association with Aloe vera L. and Brassica olearaceae L.

R. Pedrosa, V. Fávere, M. Laranjeira, 2006, Phytotherapy research : PTR.

Ultrasonic-assisted extraction combined with sample preparation and analysis using LC-ESI-MS/MS allowed the identification of 24 new phenolic compounds in pecan nut shell [Carya illinoinensis (Wangenh) C. Koch] extracts.

R. Pedrosa, G. Micke, J. M. Block, 2018, Food research international.

Brazilian Bidens pilosa Linné yields fraction containing quercetin-derived flavonoid with free radical scavenger activity and hepatoprotective effects

R. Pedrosa, D. W. Filho, K. Felipe, 2011, The Libyan journal of medicine.

Hsp90 cleavage by an oxidative stress leads to its client proteins degradation and cancer cell death.

O. Feron, J. Verrax, P. Calderon, 2009, Biochemical pharmacology.

Inhibition of cell proliferation and migration by oxidative stress from ascorbate-driven juglone redox cycling in human bladder-derived T24 cells.

C. Glorieux, J. Verrax, B. Sid, 2012, Biochemical and biophysical research communications.

Healing effect of Dillenia indica fruit extracts standardized to betulinic acid on ultraviolet radiation-induced psoriasis-like wounds in rats

F. Petronilho, R. Pedrosa, D. Moterle, 2016, Pharmaceutical biology.

Ascorbate/menadione-induced oxidative stress kills cancer cells that express normal or mutated forms of the oncogenic protein Bcr-Abl. An in vitro and in vivo mechanistic study

C. Glorieux, L. Knoops, J. Verrax, 2011, Investigational New Drugs.

Anticancer activity of flavonol and flavan-3-ol rich extracts from Croton celtidifolius latex

E. B. Parisotto, R. Pedrosa, D. W. Filho, 2013, Pharmaceutical biology.

Bioaccumulation and toxic effects of copper in common onion Allium cepa L.

R. Pedrosa, D. Fattorini, V. Fávere, 2010 .

Novel pyrimidinic selenourea induces DNA damage, cell cycle arrest, and apoptosis in human breast carcinoma.

R. Pedrosa, G. Almeida, R. F. Canto, 2018, European journal of medicinal chemistry.

Novel selenylated imidazo[1,2-a]pyridines for breast cancer chemotherapy: Inhibition of cell proliferation by Akt-mediated regulation, DNA cleavage and apoptosis.

R. Pedrosa, D. W. Filho, G. Almeida, 2018, Biochemical and biophysical research communications.

ANTIOXIDANT POTENTIAL OF Casearia sylvestris EXTRACTS

R. Pedrosa, S. R. Ferreira, P. Benelli, 2013 .

Antihyperlipidemic effect of Casearia sylvestris methanolic extract.

R. Pedrosa, C. Pich, J. Bettiol, 2008, Fitoterapia.

Piper nigrum ethanolic extract rich in piperamides causes ROS overproduction, oxidative damage in DNA leading to cell cycle arrest and apoptosis in cancer cells.

R. Pedrosa, D. W. Filho, C. Pich, 2016, Journal of ethnopharmacology.

Antioxidant and antimicrobial activities of shiitake (Lentinula edodes) extracts obtained by organic solvents and supercritical fluids

R. Pedrosa, S. R. Ferreira, C. S. G. Kitzberger, 2007 .

Hypolipidaemic activity of methanol extract of Aleurites moluccana

R. Yunes, R. Pedrosa, V. Cechinel-Filho, 2002, Phytotherapy research : PTR.

Study of the antitumor potential of Bidens pilosa (Asteraceae) used in Brazilian folk medicine.

R. Pedrosa, D. W. Filho, K. Felipe, 2008, Journal of ethnopharmacology.

The antitumor activity of extracts from Cordia verbenacea D.C. obtained by supercritical fluid extraction

E. B. Parisotto, R. Pedrosa, D. W. Filho, 2012 .

Proanthocyanidin profile and antioxidant capacity of Brazilian Vitis vinifera red wines

M. Bordignon-Luiz, R. Pedrosa, F. Mattivi, 2011 .

Cytotoxic, Hypoglycemic Activity And Phytochemical Analysis Of Rubus Imperialis (Rosaceae)

R. Yunes, R. Pedrosa, F. Monache, 2002, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Chemical profile, antimicrobial potential, and antiaggregant activity of supercritical fluid extract from Agaricus bisporus

A. D. de Moraes, E. B. Parisotto, R. Pedrosa, 2022, Chemical Papers.

Aqueous extract from pecan nut [Carya illinoinensis (Wangenh) C. Koch] shell show activity against breast cancer cell line MCF-7 and Ehrlich ascites tumor in Balb-C mice.

I. M. Toaldo, R. Pedrosa, J. M. Block, 2018, Journal of ethnopharmacology.

Phase equilibrium data of guaçatonga (Casearia sylvestris) extract + ethanol + CO2 system and encapsulation using a supercritical anti-solvent process

J. V. Oliveira, R. Pedrosa, S. R. Ferreira, 2014 .

PARTICLE FORMATION OF Casearia sylvestris EXTRACT

R. Pedrosa, S. R. R. Comim, J. V. Oliveira, 2014 .

CDK2 and Bcl-xL inhibitory mechanisms by docking simulations and anti-tumor activity from piperine enriched supercritical extract.

R. Pedrosa, Kátia S. Andrade, S. R. Ferreira, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Antitumor activity of conventional and supercritical extracts from Piper nigrum L. cultivar Bragantina through cell cycle arrest and apoptosis induction

R. Pedrosa, G. Micke, Kátia S. Andrade, 2017 .

Pheomelanin-coated iron oxide magnetic nanoparticles: a promising candidate for negative T2 contrast enhancement in magnetic resonance imaging.

R. Pedrosa, C. E. D. de Campos, B. Szpoganicz, 2015, Chemical communications.

Effect of lactase, transglutaminase and temperature on ice cream crystal by a response surface methodology approach

R. Pedrosa, E. Sant’Anna, S. Carpes, 2020 .

Molecular chaperone Hsp90 as a target for oxidant-based anticancer therapies.

C. Glorieux, J. Verrax, P. Calderon, 2011, Current medicinal chemistry.

SFE from Bidens pilosa Linné to obtain extracts rich in cytotoxic polyacetylenes with antitumor activity

R. Pedrosa, S. R. Ferreira, C. Pich, 2011 .

Apoptosis oxidative damage‐mediated and antiproliferative effect of selenylated imidazo[1,2‐a]pyridines on hepatocellular carcinoma HepG2 cells and in vivo

A. Zamoner, R. Pedrosa, D. W. Filho, 2020, Journal of biochemical and molecular toxicology.

The Widely Used Antihelmintic Drug Albendazole is a Potent Inducer of Loss of Heterozygosity

R. Medema, J. Raaijmakers, R. Pedrosa, 2021, Frontiers in Pharmacology.

Sodium orthovanadate associated with pharmacological doses of ascorbate causes an increased generation of ROS in tumor cells that inhibits proliferation and triggers apoptosis.

J. Verrax, P. Calderon, R. Pedrosa, 2013, Biochemical and biophysical research communications.

Estradiol and 1α,25(OH)2 vitamin D3 share plasma membrane downstream signal transduction through calcium influx and genomic activation in immature rat testis.

R. Pedrosa, L. Zanatta, Fátima Regina Mena Barreto Silva, 2021, Theriogenology.

Effect of different oxygen tensions on weight gain, feed conversion, and antioxidant status in piapara, Leporinus elongatus (Valenciennes, 1847)

Rozangela Curi Pedrosa, R. Pedrosa, D. W. Filho, 2005 .

Docking and molecular dynamics predicted B-DNA and dihydropyrimidinone selenoesters interactions elucidating antiproliferative effects on breast adenocarcinoma cells

R. Pedrosa, D. W. Filho, A. L. Braga, 2021, Journal of biomolecular structure & dynamics.

Redox-active quinones and ascorbate: an innovative cancer therapy that exploits the vulnerability of cancer cells to oxidative stress.

C. Glorieux, J. Verrax, P. Calderon, 2011, Anti-cancer agents in medicinal chemistry.

Albendazole as a promising molecule for tumor control

E. B. Parisotto, R. Pedrosa, D. W. Filho, 2016, Redox biology.

DNA Damage and Inhibition of Akt Pathway in MCF-7 Cells and Ehrlich Tumor in Mice Treated with 1,4-Naphthoquinones in Combination with Ascorbate

J. Benites, R. Pedrosa, J. Valderrama, 2015, Oxidative medicine and cellular longevity.

Effect of crosslinking agents on chitosan microspheres in controlled release of diclofenac sodium

R. Pedrosa, V. Fávere, M. Laranjeira, 2005 .

Free-radical scavenging by Ouratea parviflora in experimentally-induced liver injuries

R. Yunes, R. Pedrosa, D. W. Filho, 2006, Redox report : communications in free radical research.

Green processes in Foodomics. Supercritical Fluid Extraction of Bioactives

R. Pedrosa, S. R. Ferreira, Simone Mazzutti, 2021 .

In vivo antitumor activity of by-products of Passiflora edulis f. flavicarpa Deg. Rich in medium and long chain fatty acids evaluated through oxidative stress markers, cell cycle arrest and apoptosis induction.

R. Pedrosa, D. W. Filho, G. Micke, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Radical-scavenging activity of extracts from Cordia verbenacea DC obtained by different methods

R. Pedrosa, S. R. Ferreira, E. M. Michielin, 2011 .

Free radical scavenging of grape pomace extracts from Cabernet sauvingnon (Vitis vinifera).

R. Pedrosa, F. Leimann, S. R. Ferreira, 2008, Bioresource technology.

Influence of season and pollution on the antioxidant defenses of the cichlid fish acará (Geophagus brasiliensis).

R. Pedrosa, D. W. Filho, D. Wilhelm Filho, 2001, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

IP-Se-06, a Selenylated Imidazo[1,2-a]pyridine, Modulates Intracellular Redox State and Causes Akt/mTOR/HIF-1α and MAPK Signaling Inhibition, Promoting Antiproliferative Effect and Apoptosis in Glioblastoma Cells

A. Zamoner, R. Pedrosa, D. W. Filho, 2022, Oxidative medicine and cellular longevity.

Time-dependent oxidative stress caused by benznidazole

A. D. de Bem, R. Pedrosa, D. W. Filho, 2001, Redox report : communications in free radical research.

R. Pedrosa, L. Zanatta, M. Fang, 2013, BioMed research international.

Dietary supplementation with procyanidin-rich Pinus pinaster extract is associated with attenuated Ehrlich tumor development in mice.

F. Bobinski, D. Martins, R. Pedrosa, 2019, Nutrition research.

Use of Chitosan Microspheres As Remedial Material For Acidity and Iron (III) Contents Of Coal Mining Wastewaters

R. Pedrosa, M. Laranjeira, A. O. Martins, 2004, Environmental technology.

β-carboline alkaloid harmine induces DNA damage and triggers apoptosis by a mitochondrial pathway: study in silico, in vitro and in vivo

R. Pedrosa, D. W. Filho, G. Almeida, 2020 .

Lippia sidoides essential oil (Verbenaceae) improves inflammatory response and histological condition in Danio rerio

R. Pedrosa, M. L. Martins, M. S. Owatari, 2023, Aquaculture International.

The 2',4',6'-trihydroxyacetophenone isolated from Myrcia multiflora has antiobesity and mixed hypolipidemic effects with the reduction of lipid intestinal absorption.

R. Pedrosa, D. W. Filho, L. F. D. de Oliveira, 2011, Planta Medica.

Evidence of anti-obesity and mixed hypolipidemic effects of extracts from pink shrimp (Penaeus brasiliensis and Penaeus paulensis) processing residue

M. T. Friedrich, R. Pedrosa, S. R. Ferreira, 2015 .

Novel Dihydropyrimidinone-Derived Selenoesters as Potential Cytotoxic Agents to Human Hepatocellular Carcinoma: Molecular docking and DNA Fragmentation.

R. Pedrosa, D. W. Filho, A. L. Braga, 2020, Anti-cancer agents in medicinal chemistry.

Ehrlich ascites tumor-bearing mice treated with aqueous ethanol plant extract from Euphorbia tirucalli showed signs of systemic toxicity

E. B. Parisotto, R. Pedrosa, L. Kanis, 2017 .

Phenolic profile and effect of regular consumption of Brazilian red wines on in vivo antioxidant activity

M. Bordignon-Luiz, R. Pedrosa, D. W. Filho, 2013 .

Remediation of coal mining wastewaters using chitosan microspheres

R. Pedrosa, V. Fávere, M. Laranjeira, 2003, Environmental technology.

Targeting ROS overgeneration by N-benzyl-2-nitro-1-imidazole-acetamide as a potential therapeutic reposition approach for cancer therapy

R. Pedrosa, D. W. Filho, C. Pich, 2019, Investigational New Drugs.

Synthesis and Anticancer Evaluation of 4-Chloro-2-((5-aryl-1,3,4-oxadiazol-2-yl)amino)phenol Analogues: An Insight into Experimental and Theoretical Studies

Salahuddin, R. Pedrosa, O. Afzal, 2023, Molecules.

Inhibition of cell proliferation and migration by oxidative stress from ascorbate-driven juglone redox cycling in human bladder-derived T24 cells.

J. Verrax, P. Calderon, B. Sid, 2012, Biochemical and biophysical research communications.

Oxidative stress markers in adults 2 years after Roux-en-Y gastric bypass

E. Moreira, R. Pedrosa, H. Vannucchi, 2013, European journal of gastroenterology & hepatology.

Efficacy assessment of acid mine drainage treatment with coal mining waste using Allium cepa L. as a bioindicator.

R. Pedrosa, V. T. de Fávere, D. Wilhelm-Filho, 2012, Ecotoxicology and environmental safety.

Glyphosate-induced glioblastoma cell proliferation: Unraveling the interplay of oxidative, inflammatory, proliferative, and survival signaling pathways.

A. Zamoner, R. Pedrosa, F. Ourique, 2023, Environmental pollution.