C. Dai

发表

Lipid Droplet Accumulation in Human Pancreatic Islets Is Dependent On Both Donor Age and Health

Gopika G. Nair, R. Stein, X. Tong, 2019, Diabetes.

In human immature BFU-E tumor necrosis factor-alpha not only downregulates CDK6 but also directly produces apoptosis which is prevented by stem cell factor.

C. Dai, I. Chung, S. Krantz, 2004, Experimental hematology.

Inactivation of specific β cell transcription factors in type 2 diabetes.

Maike Sander, R. Stein, R. Robertson, 2013, The Journal of clinical investigation.

Vascular Endothelial Growth Factor-A and Islet Vascularization Are Necessary in Developing, but Not Adult, Pancreatic Islets

O. McGuinness, C. Dai, A. Powers, 2013, Diabetes.

Islet microenvironment, modulated by vascular endothelial growth factor-A signaling, promotes β cell regeneration.

S. Levy, C. Dai, A. Powers, 2014, Cell metabolism.

Polycythaemia vera. IV. Specific binding of stem cell factor to normal and polycythaemia vera highly purified erythroid progenitor cells

S. Koury, C. Dai, Sanford Krantz, 1994, British journal of haematology.

Polycythemia vera blood burst-forming units-erythroid are hypersensitive to interleukin-3.

C. Dai, S. Krantz, H. Gilbert, 1991, The Journal of clinical investigation.

Polycythemia vera. II. Hypersensitivity of bone marrow erythroid, granulocyte-macrophage, and megakaryocyte progenitor cells to interleukin-3 and granulocyte-macrophage colony-stimulating factor.

C. Dai, H. Gilbert, E. Dessypris, 1992, Blood.

p16Ink4a-induced senescence of pancreatic beta cells enhances insulin secretion

A. Klochendler, Y. Dor, B. Glaser, 2016, Nature Medicine.

PTP-MEG2 is activated in polycythemia vera erythroid progenitor cells and is required for growth and expansion of erythroid cells.

Z. Zhao, R. Zhao, C. Dai, 2003, Blood.

Heterozygous SOD2 Deletion Impairs Glucose-Stimulated Insulin Secretion, but Not Insulin Action, in High-Fat–Fed Mice

P. Neufer, D. Wasserman, C. Dai, 2014, Diabetes.

Dapagliflozin does not directly affect human α or β cells.

O. McGuinness, C. Dai, John T. Walker, 2020, Endocrinology.

ACSL4 is essential for radiation-induced intestinal injury by initiating ferroptosis

Yumeng Huang, C. Dai, Xu Wang, 2022, Cell death discovery.

Reduction of cell cycle progression in human erythroid progenitor cells treated with tumour necrosis factor alpha occurs with reduced CDK6 and is partially reversed by CDK6 transduction

J. Price, C. Dai, I. Chung, 2003, British journal of haematology.

Purification of human blood burst‐forming units‐erythroid and demonstration of the evolution of erythropoietin receptors

S. Koury, C. Dai, K. Sawada, 1990, Journal of cellular physiology.

Human burst-forming units-erythroid need direct interaction with stem cell factor for further development.

K. Zsebo, C. Dai, S. Krantz, 1991, Blood.

Polycythemia vera. V. Enhanced proliferation and phosphorylation due to vanadate are diminished in polycythemia vera erythroid progenitor cells: a possible defect of phosphatase activity in polycythemia vera.

C. Dai, S. Krantz, S. Sawyer, 1997, Blood.

Increased erythropoiesis in polycythemia vera is associated with increased erythroid progenitor proliferation and increased phosphorylation of Akt/PKB.

C. Dai, I. Chung, S. Krantz, 2005, Experimental hematology.

Liver-Specific Disruption of the Murine Glucagon Receptor Produces α-Cell Hyperplasia

D. Drucker, M. J. Charron, C. Dai, 2013, Diabetes.

Liver-Speci ﬁ c Disruption of the Murine Glucagon Receptor Produces a -Cell Hyperplasia: Evidence for a Circulating a -Cell Growth Factor

D. Drucker, M. J. Charron, C. Dai, 2012 .

Aldosterone decreases glucose-stimulated insulin secretion in vivo in mice and in murine islets

D. Wasserman, C. Dai, A. Powers, 2011, Diabetologia.

Human islet preparations distributed for research exhibit a variety of insulin-secretory profiles.

W. Bush, C. Dai, A. Powers, 2015, American journal of physiology. Endocrinology and metabolism.

Increased expression of the INK4a/ARF locus in polycythemia vera.

C. Dai, S. Krantz, C. Dai, 2001, Blood.

Polycythemia vera. II: Hypersensitivity of bone marrow erythroid, granulocyte-macrophage, and megakaryocyte progenitor cells to interleukin-3 and granulocyte-macrophage colony-stimulating factor

C. Dai, E. Dessypris, S. Krantz, 1992 .

Interferon γ Downregulates Stem Cell Factor and Erythropoietin Receptors But Not Insulin-Like Growth Factor-I Receptors in Human Erythroid Colony-Forming Cells

J. Price, C. Dai, S. Krantz, 1997 .

Interferon gamma downregulates stem cell factor and erythropoietin receptors but not insulin-like growth factor-I receptors in human erythroid colony-forming cells.

J. Price, C. Dai, S. Krantz, 1997, Blood.

Stem cell factor can overcome inhibition of highly purified human burst‐forming units‐erythroid by interferon γ

J. Price, C. Dai, S. Krantz, 1995, Journal of cellular physiology.

Interferon γ Induces Upregulation and Activation of Caspases 1, 3, and 8 to Produce Apoptosis in Human Erythroid Progenitor Cells

C. Dai, S. Krantz, 1999 .

SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in b Cells

Diane C. Saunders, K. Kaestner, R. Stein, 2020 .

Tshz1 Regulates Pancreatic β-Cell Maturation

David N. Groff, A. Garratt, L. Fasano, 2015, Diabetes.

Purification and Culture of Erythroid Progenitor Cells

A. Wickrema, C. Dai, S. Krantz, 2002 .

Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.

S. Levy, R. Stein, K. Vickers, 2017, Cell metabolism.

RFX6-mediated dysregulation defines human β cell dysfunction in early type 2 diabetes

Stephen C. J. Parker, Diane C. Saunders, Vivek Rai, 2021, bioRxiv.

Changes in cytoskeletal proteins and their mRNAs during maturation of human erythroid progenitor cells

S. Koury, A. Wickrema, C. Dai, 1994, Journal of cellular physiology.

Stress-impaired transcription factor expression and insulin secretion in transplanted human islets.

R. Stein, C. Dai, A. Powers, 2016, The Journal of clinical investigation.

α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes

Diane C. Saunders, D. Harlan, S. Levy, 2018, Cell reports.

alpha Cell Function and Gene Expression Are Compromised in Type 1 Diabetes

Diane C. Saunders, D. Harlan, S. Levy, 2019 .

Stem cell factor increases the expression of FLIP that inhibits IFNgamma -induced apoptosis in human erythroid progenitor cells.

C. Dai, I. Chung, S. Krantz, 2003, Blood.

The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.

D. Harlan, R. Stein, L. Goodrich, 2016, American journal of physiology. Endocrinology and metabolism.

Fas ligand is present in human erythroid colony-forming cells and interacts with Fas induced by interferon gamma to produce erythroid cell apoptosis.

J. Price, T. Brunner, C. Dai, 1998, Blood.

RIPK3-mediated inflammation is a conserved β cell response to ER stress.

C. Dai, A. Powers, Wenbiao Chen, 2020, Science advances.

SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells

Diane C. Saunders, K. Kaestner, R. Stein, 2020, Cell Metabolism.

SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 are Expressed in the Pancreas but are Not Enriched in Islet Endocrine Cells

Diane C. Saunders, K. Kaestner, R. Stein, 2020, bioRxiv : the preprint server for biology.

Tacrolimus- and sirolimus-induced human β cell dysfunction is reversible and preventable.

S. Levy, C. Dai, John T. Walker, 2020, JCI insight.

Interleukin-23 receptor signaling mediates cancer dormancy and radioresistance in human esophageal squamous carcinoma cells via the Wnt/Notch pathway

Deyu Chen, Chaoming Mao, Yuepeng Zhou, 2018, Journal of Molecular Medicine.

cell factor for further development Human burst-forming units-erythroid need direct interaction with stem

C. Dai, K. Zsebo, S. Krantz, 2011 .

Transitional change of colony stimulating factor requirements for erythroid progenitors

C. Dai, K. Sawada, M. Ieko, 1991, Journal of cellular physiology.

Stem cell factor retards differentiation of normal human erythroid progenitor cells while stimulating proliferation.

K. Muta, C. Dai, M. Bondurant, 1995, Blood.

Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis.

Diane C. Saunders, S. Levy, D. Flaherty, 2019, Cell metabolism.

Cystic fibrosis-related diabetes is caused by islet loss and inflammation.

M. Drumm, W. Bush, P. MacDonald, 2018, JCI insight.

Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.

S. Levy, Y. Hang, Seung K. Kim, 2017, The Journal of clinical investigation.

PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression.

F. Pattou, A. Wiederkehr, C. Wollheim, 2009, Cell metabolism.

Interferon gamma induces upregulation and activation of caspases 1, 3, and 8 to produce apoptosis in human erythroid progenitor cells.

C. Dai, S. Krantz, 1999, Blood.

Specific binding of interferon-gamma to high affinity receptors on human erythroid colony-forming cells.

C. Dai, S. Krantz, S. Taniguchi, 1997, Experimental hematology.

Polycythaemia vera. III. Burst‐forming units‐erythroid (BFU‐E) response to stem cell factor and c‐kit receptor expression

C. Dai, H. Gilbert, S. Krantz, 1994, British journal of haematology.

Targeting Purinergic Receptor P2RX1 Modulates Intestinal Microbiota and Alleviates Inflammation in Colitis

Yuting Su, C. Dai, Xu Wang, 2021, Frontiers in Immunology.

Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding

Marcela Brissova, Ji-Young Hong, S. Levy, 2014, Development.

Decreased pancreatic acinar cell number in type 1 diabetes

Diane C. Saunders, D. Harlan, C. Dai, 2020, Diabetologia.

Pancreatic Islet Vasculature Adapts to Insulin Resistance Through Dilation and Not Angiogenesis

Alvin C. Powers, Marcela Brissova, C. Dai, 2013, Diabetes.

Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function.

Howard Y. Chang, Jing Wang, Kun Qu, 2016, Cell metabolism.

Disrupted RNA editing in beta cells mimics early stage type 1 diabetes

A. Klochendler, Y. Dor, E. Levanon, 2022, bioRxiv.

Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets

R. Stein, Y. Hang, C. Dai, 2011, Diabetologia.

CXCR2 Is Essential for Radiation-Induced Intestinal Injury by Initiating Neutrophil Infiltration

C. Dai, Jinlei Wang, Ye Tian, 2022, Journal of immunology research.

3-6-2018 α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes

Rita, Diane C. Saunders, D. Harlan, 2018 .

P2RX1-Involved Glycolytic Metabolism Supports Neutrophil Activation in Acute Pancreatitis

C. Dai, Xiaoxin Zhang, Xu Wang, 2021, Frontiers in Immunology.

Interleukin-23 receptor signaling mediates cancer dormancy and radioresistance in human esophageal squamous carcinoma cells via the Wnt/Notch pathway

Deyu Chen, Chaoming Mao, Yuepeng Zhou, 2018, Journal of Molecular Medicine.

Inactivation of specific b cell transcription factors in type 2 diabetes

R. Stein, R. Robertson, C. Dai, 2018 .

Increased sensitivity of polycythemia vera blood burst-forming units-erythroid to interleukin 3.

C. Dai, S. Krantz, H. Gilbert, 1990, Transactions of the Association of American Physicians.

Inactivation of speci c β cell transcription factors in type 2 diabetes

R. Stein, R. Robertson, C. Dai, 2017 .

Multimodal image coregistration and inducible selective cell ablation to evaluate imaging ligands

D. Skovronsky, H. Kung, P. Meda, 2011, Proceedings of the National Academy of Sciences.

G6PC2 Modulates the Effects of Dexamethasone on Fasting Blood Glucose and Glucose Tolerance.

J. K. Oeser, R. O’Brien, O. McGuinness, 2016, Endocrinology.

G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress.

J. K. Oeser, R. O’Brien, O. McGuinness, 2016, Endocrinology.

TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1

C. Dai, De-Jun Liu, Xiaoxin Zhang, 2021, Frontiers in Oncology.

Cystic fibrosis-related diabetes is caused by islet loss and Cystic fibrosis-related diabetes is caused by islet loss and inflammation inflammation

A. Spigelman, C. Dai, A. Powers, 2022 .

Stress-impaired transcription factor expression and insulin secretion in transplanted human islets.

R. Stein, C. Dai, A. Powers, 2016, The Journal of clinical investigation.

Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.

S. Levy, R. Stein, K. Vickers, 2017, Cell metabolism.

Islet microenvironment, modulated by vascular endothelial growth factor-A signaling, promotes β cell regeneration.

S. Levy, C. Dai, A. Powers, 2014, Cell metabolism.

The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.

D. Harlan, R. Stein, L. Goodrich, 2016, American journal of physiology. Endocrinology and metabolism.

G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress.

J. K. Oeser, R. O’Brien, O. McGuinness, 2016, Endocrinology.