D. McKay

D. McKay, Jun Lu, P. Bercik, 2003, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Targeting mitochondria-derived reactive oxygen species to reduce epithelial barrier dysfunction and colitis.

W. MacNaughton, Å. Keita, J. Söderholm, 2014, The American journal of pathology.

Neuroimmune Amplification and Inhibition of Mucosal Function

K. Williams, D. McKay, S. Crowe, 1993 .

Parasitic helminths: a pharmacopeia of anti-inflammatory molecules

D. McKay, J. MacDonald, M. J. Johnston, 2008, Parasitology.

The beneficial helminth parasite?

D. McKay, 2005, Parasitology.

STAT-6 Is an Absolute Requirement for Murine Rejection of Hymenolepis diminuta

D. McKay, W. Khan, 2003, The Journal of parasitology.

A Trypsin-Sensitive Proteoglycan from the Tapeworm Hymenolepis diminuta Inhibits Murine Neutrophil Chemotaxis in vitro by Suppressing p38 MAP Kinase Activation

D. McKay, F. Lopes, J. Gilleard, 2018, Journal of Innate Immunity.

Infection with an intestinal helminth parasite reduces Freund's complete adjuvant-induced monoarthritis in mice.

J. McDougall, D. McKay, K. Sharkey, 2011, Arthritis and rheumatism.

Integrative immunophysiology in the intestinal mucosa.

D. McKay, M. Perdue, 1994, The American journal of physiology.

Protein 1 and RANTES Production Epithelial Monocyte Chemoattractant Superantigen Immune Stimulation Evokes

R. Strieter, S. Kunkel, C. Hogaboam, 1999 .

Interferon-γ-induced increases in intestinal epithelial macromolecular permeability requires the Src kinase Fyn

D. McKay, D. Smyth, A. Wang, 2011, Laboratory Investigation.

Interferon-gamma regulation of intestinal epithelial permeability.

D. McKay, D. Smyth, C. Beaurepaire, 2009, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Enteric Tuft Cells in Host-Parasite Interactions

D. McKay, A. Buret, T. Allain, 2021, Pathogens.

Role of T lymphocytes in secretory response to an enteric nematode parasite

M. Baca-Estrada, D. McKay, R. D'Incà, 1995, Digestive Diseases and Sciences.

Conditioned Medium from Enterohemorrhagic Escherichia coli-Infected T84 Cells Inhibits Signal Transducer and Activator of Transcription 1 Activation by Gamma Interferon

D. McKay, P. Sherman, P. Ceponis, 2006, Infection and Immunity.

Nippostrongylus brasiliensis infection evokes neuronal abnormalities and alterations in neurally regulated electrolyte transport in rat jejunum

R. Stead, D. McKay, M. Perdue, 1996, Parasitology.

A role for the enteric nervous system in the response to helminth infections.

I. Fairweather, D. McKay, 1997, Parasitology today.

Transient Local Depletion of Foxp3+ Regulatory T Cells during Recovery from Colitis via Fas/Fas Ligand-Induced Death1

D. McKay, C. Reardon, A. Wang, 2008, The Journal of Immunology.

Production of the Alzheimer amyloid beta protein by normal proteolytic processing.

S. Estus, T. Golde, M. Shoji, 1992, Science.

Characterization of enteric functional changes evoked by in vivo anti-CD3 T cell activation.

D. McKay, S. Collins, K. Croitoru, 1999, The American journal of physiology.

The immunophysiological impact of bacterial CpG DNA on the gut.

D. McKay, James L. Watson, 2006, Clinica chimica acta; international journal of clinical chemistry.

Bidirectional crosstalk via IL‐6, PGE2 and PGD2 between murine myofibroblasts and alternatively activated macrophages enhances anti‐inflammatory phenotype in both cells

D. McKay, M. Fernando, M. Giembycz, 2016, British journal of pharmacology.

P-Selectin-Mediated Monocyte–Cerebral Endothelium Adhesive Interactions Link Peripheral Organ Inflammation To Sickness Behaviors

Q. Pittman, M. Swain, D. McKay, 2013, The Journal of Neuroscience.

Bacterial Superantigen-Treated Intestinal Epithelial Cells Upregulate Heat Shock Proteins 25 and 72 and Are Resistant to Oxidant Cytotoxicity

E. Chang, D. McKay, E. Petrof, 2004, Infection and Immunity.

Establishing epithelial-immune cell co-cultures. Effects on epithelial ion transport and permeability.

D. McKay, M. Perdue, 2002, Methods in molecular biology.

Impact of experimental colitis on mitochondrial bioenergetics in intestinal epithelial cells

D. McKay, C. Mu, G. Holloway, 2022, Scientific reports.

Crohn’s Disease Pathobiont Adherent-Invasive E coli Disrupts Epithelial Mitochondrial Networks With Implications for Gut Permeability

J. Shearer, Å. Keita, J. Söderholm, 2020, Cellular and molecular gastroenterology and hepatology.

Cryopreserved Interleukin-4-Treated Macrophages Attenuate Murine Colitis in an Integrin β7-Dependent Manner

D. McKay, J. Reyes, B. Petri, 2015, Molecular medicine.

TGF-beta suppresses IFN-gamma-STAT1-dependent gene transcription by enhancing STAT1-PIAS1 interactions in epithelia but not monocytes/macrophages.

D. McKay, C. Reardon, 2007, Journal of immunology.

Loss of Phosphoinositide 3-Kinase p110&ggr; is Protective in the Acute Phase but Detrimental in the Resolution Phase of Hapten-Induced Colitis

D. McKay, C. Waterhouse, B. Petri, 2013, Inflammatory bowel diseases.

Enterohemorrhagic Escherichia coli O157:H7 Disrupts Stat1-Mediated Gamma Interferon Signal Transduction in Epithelial Cells

D. McKay, P. Sherman, P. Ceponis, 2003, Infection and Immunity.

Interferon‐gamma signals via an ERK1/2‐ARF6 pathway to promote bacterial internalization by gut epithelia

D. McKay, D. Smyth, Brian D. Gulbransen, 2012, Cellular microbiology.

Crohn’s disease therapeutic dietary intervention (CD-TDI): study protocol for a randomised controlled trial

G. Gkoutos, H. Barkema, D. Mutch, 2022, BMJ open gastroenterology.

Brain TNF drives post-inflammation depression-like behavior and persistent pain in experimental arthritis

Q. Pittman, M. Swain, D. McKay, 2020, Brain, Behavior, and Immunity.

Immune-epithelial interactions in host defense.

D. McKay, M. C. Berin, M. Perdue, 1999, The American journal of tropical medicine and hygiene.

Involvement of Mast Cells in α7 Nicotinic Receptor Agonist Exacerbation of Freund's Complete Adjuvant–Induced Monoarthritis in Mice

J. McDougall, D. McKay, F. Lopes, 2015, Arthritis & rheumatology.

Nitric oxide regulation of colonic epithelial ion transport: a novel role for enteric glia in the myenteric plexus

D. McKay, K. Sharkey, S. MacEachern, 2011, The Journal of physiology.

Human interleukin-4–treated regulatory macrophages promote epithelial wound healing and reduce colitis in a mouse model

R. Panaccione, D. McKay, A. Shute, 2020, Science Advances.

Infliximab restores colonic barrier to adherent-invasive E. coli in Crohn’s disease via effects on epithelial lipid rafts

Å. Keita, J. Söderholm, I. Schoultz, 2018, Scandinavian journal of gastroenterology.

Suppression of colitis by adoptive transfer of helminth antigen-treated dendritic cells requires interleukin-4 receptor-α signaling

D. McKay, F. Lopes, K. Sharkey, 2017, Scientific Reports.

Nitric oxide participates in the recovery of normal jejunal epithelial ion transport following exposure to the superantigen, Staphylococcus aureus enterotoxin B.

S. Jedrzkiewicz, D. McKay, K. Sharkey, 1999, Journal of immunology.

A simple, cost-effective method for generating murine colonic 3D enteroids and 2D monolayers for studies of primary epithelial cell function.

M. Stahl, W. MacNaughton, D. McKay, 2017, American journal of physiology. Gastrointestinal and liver physiology.

Budesonide inhibits T cell-initiated epithelial pathophysiology in an in vitro model of inflammation.

D. McKay, K. Croitoru, E. Wieslander, 1996, Journal of Pharmacology and Experimental Therapeutics.

Canadian Association of Gastroenterology: Strategic Plan 2016–2020

W. MacNaughton, D. Armstrong, D. McKay, 2016, Canadian journal of gastroenterology & hepatology.

Antisecretory effects of neuropeptide Y in the mouse colon are region-specific and are lost in DSS-induced colitis

D. McKay, K. Sharkey, Winnie Ho, 2010, Regulatory Peptides.

Monocyte/macrophages evoke epithelial dysfunction: indirect role of tumor necrosis factor-alpha.

D. McKay, M. Perdue, M. Zareie, 1998, The American journal of physiology.

Control the epithelial barrier: a pivotal first line of defense.

D. McKay, C. Mckay, 2004, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

Tissue imaging reveals disruption of epithelial mitochondrial networks and loss of mitochondria-associated cytochrome-C in inflamed human and murine colon.

P. Colarusso, D. McKay, A. Chojnacki, 2022, Mitochondrion.

Worm expulsion is independent of alterations in composition of the colonic bacteria that occur during experimental Hymenolepis diminuta-infection in mice

K. McCoy, M. Strous, D. McKay, 2020, Gut microbes.

Itch induced by peripheral mu opioid receptors is dependent on TRPV1-expressing neurons and alleviated by channel activation

M. Hollenberg, W. MacNaughton, L. Basso, 2018, Scientific Reports.

Effect of region, temperature and neuronal blockade on sodium and 51Cr-EDTA transport across canine gastrointestinal mucosae in vitro.

D. McKay, P. Rangachari, M. Perdue, 1994, Comparative biochemistry and physiology. Comparative physiology.

Probiotics prevent bacterial translocation and improve intestinal barrier function in rats following chronic psychological stress

J. Söderholm, D. McKay, J. Jury, 2006 .

Green tea polyphenol (-)-epigallocatechin gallate blocks epithelial barrier dysfunction provoked by IFN-gamma but not by IL-4.

D. McKay, M. Akhtar, H. Cameron, 2004, American journal of physiology. Gastrointestinal and liver physiology.

CALL FOR PAPERS Integrative and Translational Physiology: Inflammation and Immunity in Organ System Physiology Cannabinoid 1 receptors are critical for the innate immune response to TLR4 stimulation

Q. Pittman, D. McKay, K. Sharkey, 2013 .

Cestode regulation of inflammation and inflammatory diseases.

D. McKay, José Luis García Hernández, G. Leung, 2013, International journal for parasitology.

In vitro-derived alternatively activated macrophages reduce colonic inflammation in mice.

D. McKay, N. Van Rooijen, P. Beck, 2010, Gastroenterology.

Acetic Acid Induced Ulceration in Rats Is Not Affected by Infection with Hymenolepis diminuta

J. Wallace, D. McKay, 2009, The Journal of parasitology.

Green tea polyphenol ( (cid:1) )-epigallocatechin gallate blocks epithelial barrier dysfunction provoked by IFN- (cid:2) but not by IL-4

D. McKay, M. Akhtar, H. Cameron, 2004 .

Vasoactive intestinal polypeptide regulates barrier function via mast cells in human intestinal follicle‐associated epithelium and during stress in rats

Å. Keita, J. Söderholm, D. McKay, 2013, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

Absence of the NOD2 protein renders epithelia more susceptible to barrier dysfunction due to mitochondrial dysfunction.

D. McKay, F. Lopes, A. Saxena, 2017, American journal of physiology. Gastrointestinal and liver physiology.

Good bug, bad bug: in the case of enteric inflammatory disease does the epithelium decide?

D. McKay, 2005, Memorias do Instituto Oswaldo Cruz.

Loss of Ca2+‐mediated ion transport during colitis correlates with reduced ion transport responses to a Ca2+‐activated K+ channel opener

C. Hirota, D. McKay, 2009, British journal of pharmacology.

Cathelicidins Induce Toll-Interacting Protein Synthesis to Prevent Apoptosis in Colonic Epithelium

M. Hollenberg, A. Dufour, D. McKay, 2022, Journal of Innate Immunity.

Transforming growth factor-beta regulation of epithelial tight junction proteins enhances barrier function and blocks enterohemorrhagic Escherichia coli O157:H7-induced increased permeability.

D. McKay, Aisha Nazli, Kathryn Howe, 2005, The American journal of pathology.