D. Thornton

发表

Serine Protease(s) Secreted by the Nematode Trichuris muris Degrade the Mucus Barrier

R. Grencis, S. Hasnain, M. McGuckin, 2012, PLoS neglected tropical diseases.

From mucins to mucus: toward a more coherent understanding of this essential barrier.

D. Thornton, J. Sheehan, 2004, Proceedings of the American Thoracic Society.

The lipophilic cyclic peptide cyclosporin A induces aggregation of gel-forming mucins

D. Thornton, Hisanao Kishimoto, Caroline Ridley, 2022, Scientific reports.

Identification of Molecular Intermediates in the Assembly Pathway of the MUC5AC Mucin*

D. Thornton, P. Woodman, J. Sheehan, 2004, Journal of Biological Chemistry.

MUC16 is produced in tracheal surface epithelium and submucosal glands and is present in secretions from normal human airway and cultured bronchial epithelial cells.

D. Thornton, J. Davies, I. Carlstedt, 2007, The international journal of biochemistry & cell biology.

Mucin Gene Deficiency in Mice Impairs Host Resistance to an Enteric Parasitic Infection

W. Khan, R. Grencis, S. Hasnain, 2010, Gastroenterology.

Characterization of mucins from cultured normal human tracheobronchial epithelial cells.

J. Koo, D. Thornton, J. Sheehan, 2000, American journal of physiology. Lung cellular and molecular physiology.

Ex vivo sputum analysis reveals impairment of protease-dependent mucus degradation by plasma proteins in acute asthma.

S. Muller, D. Thornton, J. Fahy, 2009, American journal of respiratory and critical care medicine.

Characterization of neopeptides in equine articular cartilage degradation

P. Clegg, M. Peffers, D. Thornton, 2015, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Desulfurization of mucin by Pseudomonas aeruginosa: influence of sulfate in the lungs of cystic fibrosis patients.

M. Elkins, D. Thornton, M. Kertesz, 2012, Journal of medical microbiology.

A glycopolymer improves vascoelasticity and mucociliary transport of abnormal cystic fibrosis mucus.

K. Chu, G. Tearney, H. Leung, 2019, JCI insight.

Heterogeneity of airways mucus: variations in the amounts and glycoforms of the major oligomeric mucins MUC5AC and MUC5B.

D. Thornton, J. Sheehan, P. S. Richardson, 2002, The Biochemical journal.

The normal trachea is cleaned by MUC5B mucin bundles from the submucosal glands coated with the MUC5AC mucin

J. Wine, D. Thornton, G. Hansson, 2017, Biochemical and biophysical research communications.

The MUC5B mucin polymer is dominated by repeating structural motifs and its topology is regulated by calcium and pH

Gareth W. Hughes, A. Roseman, D. Thornton, 2019, Scientific Reports.

Mucins: the frontline defence of the lung

D. Thornton, Caroline Ridley, 2018, Biochemical Society transactions.

Aspergillosis and the role of mucins in cystic fibrosis

D. Denning, D. Thornton, A. Horsley, 2016, Pediatric pulmonology.

Assembly and organization of the N-terminal region of mucin MUC5AC: Indications for structural and functional distinction from MUC5B

W. O'Neal, D. Thornton, C. Ehre, 2021, Proceedings of the National Academy of Sciences.

Targeted Induction of Endoplasmic Reticulum Stress Induces Cartilage Pathology

R. Poulsom, P. Arvan, R. Boot-Handford, 2009, PLoS genetics.

An unfolded protein response is the initial cellular response to the expression of mutant matrilin-3 in a mouse model of multiple epiphyseal dysplasia

R. Boot-Handford, D. Thornton, C. Clowes, 2010, Cell Stress and Chaperones.

Decreased chondrocyte proliferation and dysregulated apoptosis in the cartilage growth plate are key features of a murine model of epiphyseal dysplasia caused by a matn3 mutation.

R. Boot-Handford, K. Kadler, L. Knowles, 2007, Human molecular genetics.

A reproducible protocol for analysis of the proteome of Trypanosoma brucei by 2-dimensional gel electrophoresis.

K. Matthews, D. Thornton, F. V. van Deursen, 2003, Molecular and biochemical parasitology.

Mucins and Mucus

J. Whitsett, M. McGuckin, D. Thornton, 2015 .

The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function

T. Jowitt, K. Hayes, R. Grencis, 2019, Nature Communications.

The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation

A. Ivens, Maryam Clausen, Maria Z. Krauss, 2019, Nature Immunology.

Detection and quantitation of mucins using chemical, lectin, and antibody methods.

M. McGuckin, D. Thornton, 2000, Methods in molecular biology.

Mucinophilic and chemotactic properties of Pseudomonas aeruginosa in relation to pulmonary colonization in cystic fibrosis

D. Thornton, J. Sheehan, J. Govan, 1990, Infection and immunity.

Airway Mucus Hyperconcentration in Non-Cystic Fibrosis Bronchiectasis.

L. Simms, G. Radford-Smith, G. Radicioni, 2019, American journal of respiratory and critical care medicine.

Intestinal mucin activates human dendritic cells and IL-8 production in a glycan-specific manner

D. Thornton, M. Travis, F. Melo-González, 2018, The Journal of Biological Chemistry.

A new role for mucins in immunity: insights from gastrointestinal nematode infection.

R. Grencis, S. Hasnain, D. Thornton, 2013, The international journal of biochemistry & cell biology.

Changes in the mucosal barrier during acute and chronic Trichuris muris infection

R. Grencis, S. Hasnain, D. Thornton, 2011, Parasite immunology.

Calcium-dependent Protein Interactions in MUC5B Provide Reversible Cross-links in Salivary Mucus*

T. Hardingham, B. Raynal, D. Thornton, 2003, Journal of Biological Chemistry.

Identification of a nonmucin glycoprotein (gp-340) from a purified respiratory mucin preparation: evidence for an association involving the MUC5B mucin.

D. Thornton, J. Sheehan, P. S. Richardson, 2001, Glycobiology.

Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion

P. Dawson, R. Grencis, S. Hasnain, 2017, PLoS pathogens.

Separation and identification of mucins and their glycoforms.

D. Thornton, J. Sheehan, N. Khan, 2000, Methods in molecular biology.

Regulation of MUC5AC mucin secretion and airway surface liquid metabolism by IL-1beta in human bronchial epithelia.

J. Koo, D. Thornton, R. Boucher, 2004, American journal of physiology. Lung cellular and molecular physiology.

Functional characterization of the mucus barrier on the Xenopus tropicalis skin surface

Gareth W. Hughes, R. Grencis, I. Roberts, 2018, Proceedings of the National Academy of Sciences.

Identification in Vitreous and Molecular Cloning of Opticin, a Novel Member of the Family of Leucine-rich Repeat Proteins of the Extracellular Matrix*

D. McLeod, D. Thornton, J. Sheehan, 2000, The Journal of Biological Chemistry.

Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis

T. Waigh, D. Thornton, A. Horsley, 2014, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

From Mucins to Mucus

D. Thornton, J. Sheehan, 2012 .

Muc5b Is the Major Polymeric Mucin in Mucus from Thoroughbred Horses With and Without Airway Mucus Accumulation

P. Clegg, D. Thornton, J. Cardwell, 2011, PloS one.

TGF-β2 decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells

D. Thornton, S. Herrick, R. Gore, 2013, Experimental lung research.

Intracellular Processing of Human Secreted Polymeric Airway Mucins.

D. Thornton, Caroline Ridley, C. Sharpe, 2018, Annals of the American Thoracic Society.

Sputum biomarkers during acute severe asthma attacks in children—a case‐control study

C. Brightling, D. Thornton, L. Rapley, 2021, Acta paediatrica.

The expression of mucin genes and the presence of mucin gene products in the equine endometrium.

W. Meijer, J. Irwin, D. Thornton, 2013, Research in veterinary science.

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP.

D. Heinegård, R. Boot-Handford, K. Kadler, 2007, Human molecular genetics.

Analysis of respiratory mucus glycoproteins in asthma: a detailed study from a patient who died in status asthmaticus.

D. Thornton, D. C. Fung, J. Sheehan, 1995, American journal of respiratory cell and molecular biology.

A secretory cell type develops alongside multiciliated cells, ionocytes and goblet cells, and provides a protective, anti-infective function in the frog embryonic mucociliary epidermis

N. Papalopulu, D. Thornton, E. Amaya, 2014, Development.

Identification of Two Glycoforms of the MUC5B Mucin in Human Respiratory Mucus

D. Thornton, J. Sheehan, M. Howard, 1997, The Journal of Biological Chemistry.

Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways?

N. Alexis, D. Thornton, Genevieve DeMaria, 2008, American journal of physiology. Lung cellular and molecular physiology.

Respiratory mucins: identification of core proteins and glycoforms.

M. Price, D. Thornton, J. Sheehan, 1996, The Biochemical journal.

The UIP honeycomb airway cells are the site of mucin biogenesis with deranged cilia

D. Thornton, S. Pearson, C. Lawless, 2022, bioRxiv.

MUC5B is the major mucin in the gel phase of sputum in chronic obstructive pulmonary disease.

Dave Singh, J. Vestbo, U. Kolsum, 2008, American journal of respiratory and critical care medicine.

Mucins in COPD MUC 5 B is the major mucin in the gel-phase of sputum in chronic obstructive pulmonary disease

Dave Singh, J. Vestbo, U. Kolsum, 2008 .

Loss of matrilin 1 does not exacerbate the skeletal phenotype in a mouse model of multiple epiphyseal dysplasia caused by a Matn3 V194D mutation

R. Boot-Handford, D. Thornton, K. A. Pirog, 2012, Arthritis and rheumatism.

Identification of salivary mucin MUC7 binding proteins from Streptococcus gordonii

D. Thornton, J. Sheehan, R. Mehrotra, 2009, BMC Microbiology.

ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites

D. Schwartz, K. Hayes, M. Hepworth, 2019, The Journal of experimental medicine.

The alternatively spliced type III connecting segment of fibronectin is a zinc-binding module.

M. Humphries, D. Thornton, P. Buckley, 2007, Matrix biology : journal of the International Society for Matrix Biology.

Mucins and their receptors in chronic lung disease

D. Thornton, J. Burchell, J. Porter, 2020, Clinical & translational immunology.

Biosynthesis of the polymeric gel-forming mucin MUC5B

D. Thornton, P. Woodman, C. W. Davis, 2016, American journal of physiology. Lung cellular and molecular physiology.

Physical characterization of a low-charge glycoform of the MUC5B mucin comprising the gel-phase of an asthmatic respiratory mucous plug.

D. Thornton, J. Sheehan, M. Howard, 1999, The Biochemical journal.

Physical characterization of the MUC5AC mucin: a highly oligomeric glycoprotein whether isolated from cell culture or in vivo from respiratory mucous secretions.

D. Thornton, J. Sheehan, S. Kirkham, 2000, The Biochemical journal.

Structure and Biochemistry of Human Respiratory Mucins

D. Thornton, J. Sheehan, J. Davies, 1997 .

A detection and quantification label-free tool to speed up downstream processing of model mucins

Sofia B. Carvalho, Sofia B Carvalho, P. Alves, 2018, PloS one.

Concentrated solutions of salivary MUC5B mucin do not replicate the gel-forming properties of saliva.

T. Hardingham, B. Raynal, D. Thornton, 2002, The Biochemical journal.

Identification of glycoproteins on nitrocellulose membranes and gels

D. Thornton, J. Sheehan, I. Carlstedt, 1996, Molecular biotechnology.

Collagen XXVII Is Developmentally Regulated and Forms Thin Fibrillar Structures Distinct from Those of Classical Vertebrate Fibrillar Collagens*

R. Poulsom, R. Boot-Handford, K. Kadler, 2007, Journal of Biological Chemistry.

Expression and secretion of Aspergillus fumigatus proteases are regulated in response to different protein substrates

D. Thornton, P. Bowyer, S. Herrick, 2012, Fungal biology.

The C-terminal dimerization domain of the respiratory mucin MUC5B functions in mucin stability and intracellular packaging before secretion

T. Jowitt, Michael P. Lockhart-Cairns, C. Baldock, 2019, The Journal of Biological Chemistry.

Assembly of the Respiratory Mucin MUC5B

T. Jowitt, T. Hardingham, B. Raynal, 2014, The Journal of Biological Chemistry.

Identification of two major populations of mucins in respiratory secretions.

C. Hanski, D. Thornton, J. Sheehan, 1994, American journal of respiratory and critical care medicine.

INTERACTION BETWEEN MYCOBACTERIA AND MUCUS ON A HUMAN RESPIRATORY TISSUE ORGAN CULTURE MODEL WITH AN AIR INTERFACE

D. Thornton, R. Wilson, J. Sheehan, 2004, Experimental lung research.

An investigation of a maximum entropy method for the processing of 1H and 13C nmr spectra from glycosaminoglycan oligo- and poly-saccharides

D. Thornton, P. Sanderson, T. Huckerby, 1989 .

Detecting, visualising, and quantifying mucins.

M. McGuckin, D. Thornton, Ceri A Harrop, 2012, Methods in molecular biology.

Isolation and physical characterization of the MUC7 (MG2) mucin from saliva: evidence for self-association.

D. Thornton, J. Sheehan, R. Mehrotra, 1998, The Biochemical journal.

Cystic fibrosis: an inherited disease affecting mucin-producing organs.

D. Thornton, C. Ehre, Caroline Ridley, 2014, The international journal of biochemistry & cell biology.

Identification of glycoproteins on nitrocellulose membranes and gels.

D. Thornton, J. Sheehan, I. Carlstedt, 1994, Methods in molecular biology.

Partial characterisation of high-molecular weight glycoconjugates in the trail mucus of the freshwater pond snail Lymnaea stagnalis.

C. Mccrohan, K. White, D. Thornton, 2004, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

A novel role for Gtb1p in glucose trimming of N-linked glycans.

B. Wilkinson, S. J. Mahoney, D. Thornton, 2009, Glycobiology.

Structural and immunological studies of keratan sulphates from mature bovine articular cartilage.

A. Ratcliffe, T. Hardingham, D. Thornton, 1989, The Biochemical journal.

Quantitation of mucus glycoproteins blotted onto nitrocellulose membranes.

D. Thornton, J. Sheehan, D. Holmes, 1989, Analytical biochemistry.

Salivary mucin MG1 is comprised almost entirely of different glycosylated forms of the MUC5B gene product.

N. Packer, D. Thornton, E. Veerman, 1999, Glycobiology.

Reorganisation of the Salivary Mucin Network by Dietary Components: Insights from Green Tea Polyphenols

Heather S. Davies, Thomas A. Waigh, Caroline E. Ridley, 2014, PloS one.

Gel-forming and cell-associated mucins: preparation for structural and functional studies.

D. Thornton, J. Davies, C. Wickström, 2012, Methods in molecular biology.

Proteomic analysis of polymeric salivary mucins: no evidence for MUC19 in human saliva.

D. Rogers, P. Clegg, D. Thornton, 2008, The Biochemical journal.

Muc5b and Muc5ac are the major oligomeric mucins in equine airway mucus.

P. Clegg, D. Thornton, S. Mckane, 2007, American journal of physiology. Lung cellular and molecular physiology.

Site‐specific N‐linked glycosylation analysis on the human salivary mucin MUC5B using Precursor Ion Discovery on the CAPLC Q‐TOF system

D. Thornton, S. Kirkham, David Knight, 2004 .

Biosynthesis of the MUC2 mucin: evidence for a slow assembly of fully glycosylated units.

C. Paraskeva, D. Thornton, J. Sheehan, 1996, The Biochemical journal.

Methods for separation and deglycosylation of mucin subunits.

D. Thornton, J. Sheehan, P. Devine, 1995, Analytical biochemistry.

Evidence for shared epitopes within the 'naked' protein domains of human mucus glycoproteins. A study performed by using polyclonal antibodies and electron microscopy.

R. Boot-Handford, D. Thornton, J. Sheehan, 1991, The Biochemical journal.

Mucus glycoproteins from 'normal' human tracheobronchial secretion.

D. Thornton, J. Sheehan, J. Davies, 1990, The Biochemical journal.

Salivary mucin MG 1 is comprised almost entirely of different glycosylated forms of the MUC 5 B gene product

N. Packer, D. Thornton, E. Veerman, 1999 .

Structure and function of the polymeric mucins in airways mucus.

M. McGuckin, D. Thornton, K. Rousseau, 2008, Annual review of physiology.

Muc5b is required for airway defence

Ivana V. Yang, Richard C. Boucher, Joseph H. Sisson, 2013, Nature.

Particle tracking microrheology of purified gastrointestinal mucins.

P. Pudney, T. Waigh, D. Thornton, 2014, Biopolymers.

A sticky end for gastrointestinal helminths; the role of the mucus barrier

R. Grencis, D. Thornton, C. Sharpe, 2018, Parasite immunology.

Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis

C. Goodnow, M. Cook, D. Taupin, 2008, PLoS medicine.

Heterogeneity and size distribution of gel-forming mucins.

D. Thornton, J. Sheehan, 2000, Methods in molecular biology.

A study of the intracellular and secreted forms of the MUC2 mucin from the PC/AA intestinal cell line.

C. Paraskeva, D. Thornton, J. Sheehan, 1999, Glycobiology.

Secondary Structure and Glycosylation of Mucus Glycoproteins by Raman Spectroscopies

Volker Deckert, Heather S. Davies, Caroline E. Ridley, 2016, Analytical chemistry.

Defining the early stages of intestinal colonisation by whipworms

Anneliese O. Speak, A. Speak, N. Holroyd, 2020, Nature Communications.

A Combined Small-Angle X-ray and Neutron Scattering Study of the Structure of Purified Soluble Gastrointestinal Mucins

P. Pudney, T. Waigh, D. Thornton, 2014, Biopolymers.

TITLE 1 Defining the early stages of intestinal colonisation by whipworms 2 3

Rawlinson, A. Speak, N. Holroyd, 2021 .

Increased gut microbial mucin foraging promotes clearance of a parasitic worm

A. Macpherson, R. Grencis, D. Thornton, 2022, bioRxiv.

Influenza A induces the major secreted airway mucin MUC5AC in a protease-EGFR-extracellular regulated kinase-Sp1-dependent pathway.

L. Touqui, J. Sallenave, M. Chignard, 2012, American journal of respiratory cell and molecular biology.

Trickle infection and immunity to Trichuris muris

R. Grencis, D. Thornton, Maya Glover, 2019, bioRxiv.

High fat diet induced resistance to helminth infection via alternative induction of Type 2 immunity.

K. Hayes, R. Grencis, J. Worthington, 2023, Mucosal immunology.

Muc5ac: a critical component mediating the rejection of enteric nematodes

T. Wynn, R. Grencis, S. Hasnain, 2011, The Journal of experimental medicine.

Extracellular vesicles induce protective immunity against Trichuris muris

Gareth W. Hughes, R. Grencis, A. Bancroft, 2018, Parasite immunology.

Vaccination Against Whipworm: Identification of Potential Immunogenic Proteins in Trichuris muris Excretory/Secretory Material

R. Grencis, A. Bancroft, D. Thornton, 2018, Scientific Reports.

Mucin networks: Dynamic structural assemblies controlling mucus function.

D. Fass, D. Thornton, 2023, Current opinion in structural biology.

Monoclonal Antibody Recognizing a Core Epitope on Mucin

Y. Liew, D. Thornton, J. Sheehan, 2002, Disease markers.

Monoclonal Antibody Recognizing a Core Epitope

Y. Liew, D. Thornton, J. Sheehan, 1998 .

MUC5AC and a Glycosylated Variant of MUC5B Alter Mucin Composition in Children With Acute Asthma

C. Brightling, P. Bradding, D. Thornton, 2017, Chest.

Tea Derived Galloylated Polyphenols Cross-Link Purified Gastrointestinal Mucins

P. Pudney, T. Waigh, D. Thornton, 2014, PloS one.

Analysis of the cartilage proteome from three different mouse models of genetic skeletal diseases reveals common and discrete disease signatures

Julian N. Selley, R. Boot-Handford, D. Thornton, 2013, Biology Open.

Mucus Aberrant Properties in CF: Insights from Cells and Animal Models

D. Thornton, G. Hansson, L. Ostedgaard, 2022, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Granule-stored MUC5B mucins are packed by the non-covalent formation of N-terminal head-to-head tetramers

J. Wine, D. Thornton, G. Hansson, 2018, The Journal of Biological Chemistry.

New Role of Nod Proteins in Regulation of Intestinal Goblet Cell Response in the Context of Innate Host Defense in an Enteric Parasite Infection

D. Philpott, W. Khan, R. Grencis, 2015, Infection and Immunity.

Dropping acid: why is cystic fibrosis mucus abnormal?

B. Rubin, D. Thornton, 2018, European Respiratory Journal.

Mucin structure. The structure and heterogeneity of respiratory mucus glycoproteins.

D. Thornton, J. Sheehan, I. Carlstedt, 1991, The American review of respiratory disease.

Mucin biosynthesis and macromolecular assembly.

C. Paraskeva, C. Hanski, D. Thornton, 1995, Biochemical Society transactions.

An enzyme-linked immunosorbent assay (ELISA) of denatured cartilage link protein.

D. Thornton, J. Sheehan, I. Nieduszynski, 1987, Biochimica et biophysica acta.

Disulfide disruption reverses mucus dysfunction in allergic airway disease

Gregg A. Duncan, W. Janssen, D. Thornton, 2021, Nature Communications.

Disulfide disruption reverses mucus dysfunction in allergic airway disease

Gregg A. Duncan, W. Janssen, D. Thornton, 2019, bioRxiv.

Mucus glycoproteins from cystic fibrotic sputum. Macromolecular properties and structural 'architecture'.

H. Lindgren, D. Thornton, J. Sheehan, 1991, The Biochemical journal.

Morphologically intact airways in lung fibrosis have an abnormal proteome

D. Thornton, C. Lawless, R. Venkateswaran, 2023, Respiratory Research.

The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function

T. Jowitt, K. Hayes, R. Grencis, 2019, Nature Communications.

The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation

A. Ivens, Maryam Clausen, Maria Z. Krauss, 2019, Nature Immunology.

Structural and Functional Characterization of Recombinant Matrilin-3 A-domain and Implications for Human Genetic Bone Diseases*

L. Ala‐Kokko, T. Jowitt, D. Thornton, 2007, Journal of Biological Chemistry.

Measuring Airway Mucin 2 in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization.

D. Thornton, J. Fahy, R. Boucher, 2016, Annals of the American Thoracic Society.

The glycosaminoglycans of pig colonic wall connective tissue.

D. Thornton, T. Huckerby, S. Hunt, 1983, Biochimica et biophysica acta.

Mucins : methods and protocols

M. McGuckin, D. Thornton, 2012 .

Multiwavelength analyses of derivative spectra: an application for the determination of urinary porphyrins.

D. Thornton, M. Walters, 1986, Clinica chimica acta; international journal of clinical chemistry.

Mucins

M. McGuckin, D. Thornton, 2012, Methods in Molecular Biology.

Mucus

D. Thornton, Caroline Ridley, A. M. Jaramillo, 2021, Current Biology.

Proteomic analysis of mouse growth plate cartilage

D. Thornton, J. Gorman, D. Belluoccio, 2006, Proteomics.

Changes in the mucosal barrier during acute and chronic Trichuris muris infection

R. Grencis, S. Hasnain, D. Thornton, 2011, Parasite immunology.

Electron-microscopic and electrophoretic studies of bovine femoral-head cartilage proteoglycan fractions.

D. Thornton, J. Sheehan, K. Oates, 1986, Biochemical Journal.

A glycopolymer improves vascoelasticity and mucociliary transport of abnormal cystic fibrosis mucus.

Gareth W. Hughes, K. Chu, G. Tearney, 2019, JCI insight.

The normal trachea is cleaned by MUC5B mucin bundles from the submucosal glands coated with the MUC5AC mucin

J. Wine, D. Thornton, G. Hansson, 2017, Biochemical and biophysical research communications.

Desulfurization of mucin by Pseudomonas aeruginosa: influence of sulfate in the lungs of cystic fibrosis patients.

M. Elkins, D. Thornton, M. Kertesz, 2012, Journal of medical microbiology.

Structural studies of two populations of keratan sulphate chains from mature bovine articular cartilage

D. Thornton, T. Huckerby, I. Nieduszynski, 2005, Glycoconjugate Journal.

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP.

D. Heinegård, R. Boot-Handford, K. Kadler, 2007, Human molecular genetics.

Mucin-degrading gut bacteria promote anti-parasitic immunity

A. Macpherson, R. Grencis, D. Thornton, 2024, bioRxiv.

Vaccination Against Whipworm: Identification of Potential Immunogenic Proteins in Trichuris muris Excretory/Secretory Material

R. Grencis, A. Bancroft, D. Thornton, 2018, Scientific Reports.

Heterogeneity of mucus glycoproteins from cystic fibrotic sputum. Are there different families of mucins?

D. Thornton, J. Sheehan, I. Carlstedt, 1991, The Biochemical journal.