J. Kaper

发表

Enterohemorrhagic E. coli (EHEC)—Secreted Serine Protease EspP Stimulates Electrogenic Ion Transport in Human Colonoid Monolayers

M. Donowitz, O. Kovbasnjuk, C. Tse, 2018, Toxins.

Cloning and Sequencing of the Genes Downstream of thewbf Gene Cluster of Vibrio cholerae Serogroup O139 and Analysis of the Junction Genes in Other Serogroups

J. Morris, G. Nair, J. Kaper, 1999, Infection and Immunity.

Cloning, characterization, and chromosomal mapping of a phospholipase (lecithinase) produced by Vibrio cholerae

R. Russell, J. Kaper, A. Fiore, 1997, Infection and immunity.

Vibrio cholerae . attenuated cholera vaccines and by El Tor and in diarrhea caused by selected new , live New evidence for an inflammatory component

C. Tacket, R. Guerrant, J. Kaper, 1996 .

Cholera: pathogenesis and vaccine development

M. Levine, J. Kaper, 1996 .

New evidence for an inflammatory component in diarrhea caused by selected new, live attenuated cholera vaccines and by El Tor and Q139 Vibrio cholerae

C. Tacket, R. Guerrant, J. Kaper, 1996, Infection and immunity.

Occurrence of Vibrio cholerae serotype O1 in Maryland and Louisiana estuaries

D. Maneval, R. Colwell, E. Remmers, 1981, Applied and environmental microbiology.

Molecular characterization of environmental and nontoxigenic strains of Vibrio cholerae

J. Kaper, S. Moseley, S. Falkow, 1981, Infection and immunity.

Molecular epidemiology of Vibrio cholerae in the U.S. Gulf Coast

J. Kaper, S. Falkow, H. Bradford, 1982, Journal of clinical microbiology.

Nucleotide sequence analysis of the A2 and B subunits of Vibrio cholerae enterotoxin.

J. Kaper, H. Lockman, 1983, The Journal of biological chemistry.

Induction of Interleukin-8 in T84 Cells by Vibrio cholerae

J. Kaper, J. Benitez, J. Michalski, 2004, Infection and Immunity.

Pathogenicity Islands and Other Mobile Virulence Elements of Vibrio cholerae

J. Kaper, D. Karaolis, 1999 .

Volunteer studies of deletion mutants of Vibrio cholerae O1 prepared by recombinant techniques

M. Levine, J. Morris, R. Black, 1988, Infection and immunity.

Safety and immunogenicity of live oral cholera vaccine candidate CVD 110, a delta ctxA delta zot delta ace derivative of El Tor Ogawa Vibrio cholerae.

M. Levine, C. Tacket, J. Nataro, 1993, The Journal of infectious diseases.

A Vibrio cholerae pathogenicity island associated with epidemic and pandemic strains.

E. Boedeker, J. Kaper, P. Reeves, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Fitness cost of the green fluorescent protein in gastrointestinal bacteria.

Camilla Rang, Lin Chao, L. Chao, 2003, Canadian journal of microbiology.

Pathogenicity islands and the evolution of microbes.

J. Hacker, J. Kaper, 2000, Annual review of microbiology.

Sensitivity and specificity of DNA probes with the stool blot technique for detection of Escherichia coli enterotoxins.

M. Levine, R. Black, J. Kaper, 1985, The Journal of infectious diseases.

Comparison of DNA probes and the Sereny test for identification of invasive Shigella and Escherichia coli strains

J. Morris, J. Kaper, O. Sethabutr, 1986, Journal of clinical microbiology.

Blinded, two-laboratory comparative analysis of Escherichia coli heat-stable enterotoxin production by using monoclonal antibody enzyme-linked immunosorbent assay, radioimmunoassay, suckling mouse assay, and gene probes

M. Levine, H. Brandwein, J. Kaper, 1986, Journal of clinical microbiology.

Diarrheagenic Escherichia coli

James P. Nataro, J. Nataro, J. Kaper, 1998, Clinical Microbiology Reviews.

Plasmid and chromosomal elements involved in the pathogenesis of attaching and effacing Escherichia coli

J. Kaper, A. Jerse, K. Gicquelais, 1991, Infection and immunity.

Pathogenic Escherichia coli

Harry L. T. Mobley, James P. Nataro, H. Mobley, 2004, Nature Reviews Microbiology.

A genetic locus of enteropathogenic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cells.

J. Yu, J. Kaper, B. Tall, 1990, Proceedings of the National Academy of Sciences of the United States of America.

A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K‐12

T. McDaniel, J. Kaper, T K McDaniel, 1997, Molecular microbiology.

Identification and Characterization of lpfABCC′DE, a Fimbrial Operon of Enterohemorrhagic Escherichia coli O157:H7

F. Blattner, N. Perna, V. Burland, 2002, Infection and Immunity.

Cross-Talk between Probiotic Nissle 1917 and Human Colonic Epithelium Affects the Metabolite Composition and Demonstrates Host Antibacterial Effect

O. Kovbasnjuk, J. Kaper, K. Dokładny, 2021, Metabolites.

Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector

J. Kaper, M. Donnenberg, M S Donnenberg, 1991, Infection and immunity.

H-NST Induces LEE Expression and the Formation of Attaching and Effacing Lesions in Enterohemorrhagic Escherichia coli

D. Rasko, J. Kaper, T. H. Hazen, 2014, PloS one.

Oral Cholera Vaccines

J. Kaper, J. Holmgren, 2016 .

Contribution of Urease to Colonization by Shiga Toxin-Producing Escherichia coli

J. Kaper, Susan R. Steyert, 2012, Infection and Immunity.

An activator of glutamate decarboxylase genes regulates the expression of enteropathogenic Escherichia coli virulence genes through control of the plasmid‐encoded regulator, Per

J. Foster, J. Kaper, M. Castanié-Cornet, 2001, Molecular microbiology.

Cloning and characterization of the Bacteroides fragilis metalloprotease toxin gene

A. Franco, J. Kaper, C. Sears, 1997, Infection and immunity.

Vaccination and autoimmunity

R. Rappuoli, M. Goldman, M. Good, 2004 .

Serine Protease EspP from Enterohemorrhagic Escherichia Coli Is Sufficient to Induce Shiga Toxin Macropinocytosis in Intestinal Epithelium

O. Kovbasnjuk, E. Boedeker, Julie G. In, 2013, PloS one.

Enteropathogenic Escherichia coli O 125 : H 6 Triggers Attaching and Effacing Lesions on Human Intestinal Biopsy Specimens Independently of Nck and TccP / TccP 2

J. Kaper, A. Mousnier, A. Whale, 2007 .

Enteropathogenic Escherichia coli O125:H6 Triggers Attaching and Effacing Lesions on Human Intestinal Biopsy Specimens Independently of Nck and TccP/TccP2

J. Kaper, A. Mousnier, A. Whale, 2007, Infection and Immunity.

Enteropathogenic and enterohaemorrhagic Escherichia coli : more subversive elements

G. Dougan, J. Kaper, I. Rosenshine, 1998, Molecular microbiology.

The Cloned Locus of Enterocyte Effacement from EnterohemorrhagicEscherichia coli O157:H7 Is Unable To Confer the Attaching and Effacing Phenotype upon E. coliK-12

J. Kaper, S. Elliott, Jie Yu, 1999, Infection and Immunity.

Synergistic role of curli and cellulose in cell adherence and biofilm formation of attaching and effacing Escherichia coli and identification of Fis as a negative regulator of curli.

J. Kaper, J. Puente, A. Phillips, 2009, Environmental microbiology.

The Concept of Pathogenicity Islands

J. Hacker, J. Kaper, 1999 .

Interactions between enteropathogenic Escherichia coli and host epithelial cells.

B. Finlay, J. Kaper, M. Donnenberg, 1997, Trends in Microbiology.

Genetics of virulence of enteropathogenic E. coli.

T. McDaniel, K. Jarvis, J. Kaper, 1997, Advances in experimental medicine and biology.

Insertion site of the locus of enterocyte effacement in enteropathogenic and enterohemorrhagic Escherichia coli differs in relation to the clonal phylogeny of the strains

T. McDaniel, T. Whittam, L. Wieler, 1997 .

Attenuated live cholera vaccine strain CVD 103-HgR elicits significantly higher serum vibriocidal antibody titers in persons of blood group O

M. Levine, G. Losonsky, J. Kaper, 1995, Infection and immunity.

Live oral cholera vaccine : from principle to product

M. Levine, J. Kaper, 1995 .

Recombinant nontoxinogenic Vibrio cholerae strains as attenuated cholera vaccine candidates

M. Levine, J. Kaper, H. Lockman, 1984, Nature.

A Recombinant Live Oral Cholera Vaccine

M. Levine, J. Kaper, H. Lockman, 1984, Bio/Technology.

The role of the eaeA gene in diarrhea and neurological complications in a gnotobiotic piglet model of enterohemorrhagic Escherichia coli infection

F. Gunzer, S. Tzipori, J. Kaper, 1995, Infection and immunity.

Vibrio cholerae, Vibrio parahaemolyticus, and other vibrios: occurrence and distribution in Chesapeake Bay.

R. Colwell, J. Kaper, S. Joseph, 1977, Science.

Medium for the presumptive identification of Aeromonas hydrophila and Enterobacteriaceae

R. Colwell, J. Kaper, R. Seidler, 1979, Applied and environmental microbiology.

New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development

M. Levine, R. Black, J. Kaper, 1983 .

The role of the eae gene of enterohemorrhagic Escherichia coli in intimate attachment in vitro and in a porcine model.

M. McKee, S. Tzipori, J. Alroy, 1993, The Journal of clinical investigation.

Secretion of extracellular proteins by enterohemorrhagic Escherichia coli via a putative type III secretion system

K. Jarvis, J. Kaper, 1996, Infection and immunity.

Longus pilus of enterotoxigenic Escherichia coli and its relatedness to other type-4 pili--a minireview.

K. Jarvis, J. Kaper, J. Girón, 1997, Gene.

Flagellin of Enteropathogenic Escherichia coli Stimulates Interleukin-8 Production in T84 Cells

A. Torres, J. Kaper, Xin Zhou, 2003, Infection and Immunity.

Cytoskeletal composition of attaching and effacing lesions associated with enteropathogenic Escherichia coli adherence to HeLa cells

B. Finlay, J. Kaper, I. Rosenshine, 1992, Infection and immunity.

Signal transduction between enteropathogenic Escherichia coli (EPEC) and epithelial cells: EPEC induces tyrosine phosphorylation of host cell proteins to initiate cytoskeletal rearrangement and bacterial uptake.

B. Finlay, J. Kaper, I. Rosenshine, 1992, The EMBO journal.

Novel form of actin-based motility transports bacteria on the surfaces of infected cells.

J. Kaper, J. Sanger, J. W. Sanger, 1996, Cell motility and the cytoskeleton.

Adherence of Diarrheagenic Escherichia coli Strains to Epithelial Cells

A. Torres, J. Kaper, Xin Zhou, 2005, Infection and Immunity.

Serological response to type 1-like somatic fimbriae in diarrheal infection due to classical enteropathogenic Escherichia coli.

M. Levine, H. Karch, J. Kaper, 1987, Microbial pathogenesis.

Characterization of enteroadherent-aggregative Escherichia coli, a putative agent of diarrheal disease.

D. Maneval, M. Levine, H. Lior, 1988, The Journal of infectious diseases.

Enteroaggregative Escherichia coli associated with persistent diarrhea in a cohort of rural children in India.

M. Levine, J. Kaper, S. Sazawal, 1989, The Journal of infectious diseases.

Role of type 1 fimbriae in EPEC infections.

J. Kaper, S. Elliott, 1997, Microbial pathogenesis.

Role of Intimin and Bundle-Forming Pili in Enteropathogenic Escherichia coli Adhesion to Pediatric Intestinal Tissue In Vitro

G. Dougan, J. Kaper, G. Frankel, 1998, Infection and Immunity.

Pathogenicity Islands and the Evolution of Pathogenic Microbes

J. Hacker, J. Kaper, 2002, Current Topics in Microbiology and Immunology.

Thermostable direct hemolysin gene of Vibrio parahaemolyticus: a virulence gene acquired by a marine bacterium

J. Kaper, M. Nishibuchi, 1995, Infection and immunity.

Potential for reacquisition of cholera enterotoxin genes by attenuated Vibrio cholerae vaccine strain CVD 103-HgR

M. Levine, J. Kaper, J. Michalski, 1994, Infection and immunity.

The capsule and O antigen in Vibrio cholerae O139 Bengal are associated with a genetic region not present in Vibrio cholerae O1

D. Maneval, M. Levine, J. Kaper, 1995, Infection and immunity.

Cloning and sequence of a region encoding a surface polysaccharide of Vibrio cholerae O139 and characterization of the insertion site in the chromosome of Vibrio cholerae O1

J. Kaper, Judith A. Johnson, J. Michalski, 1996, Molecular microbiology.

Tandem tyrosine phosphosites in the Enteropathogenic Escherichia coli chaperone CesT are required for differential type III effector translocation and virulence

A. Abe, A. Stadnyk, J. Kaper, 2018, Molecular microbiology.

A DNA probe to identify enterohemorrhagic Escherichia coli of O157:H7 and other serotypes that cause hemorrhagic colitis and hemolytic uremic syndrome.

M. Levine, H. Lior, H. Karch, 1987, The Journal of infectious diseases.

The cytolysin gene of Vibrio vulnificus: sequence and relationship to the Vibrio cholerae E1 Tor hemolysin gene

J. Morris, A. Wright, J. Kaper, 1990, Infection and immunity.

Cloning of the cytotoxin-hemolysin gene of Vibrio vulnificus

D. Maneval, J. Morris, A. Wright, 1985, Infection and immunity.

Construction and analysis of TnphoA mutants of enteropathogenic Escherichia coli unable to invade HEp-2 cells

G. Keusch, S. Calderwood, J. Kaper, 1990, Infection and immunity.

A plasmid-encoded regulatory region activates chromosomal eaeA expression in enteropathogenic Escherichia coli

J. Kaper, O. Gómez-Duarte, 1995, Infection and immunity.

Secondary Vibrio cholerae-specific cellular antibody responses following wild-type homologous challenge in people vaccinated with CVD 103-HgR live oral cholera vaccine: changes with time and lack of correlation with protection

M. Levine, C. Tacket, G. Losonsky, 1993, Infection and immunity.

Long polar fimbriae and tissue tropism in Escherichia coli O157:H7.

A. Torres, M. Thomson, J. Kaper, 2006, Microbes and infection.

Adherence of Diarrheagenic Escherichia coli Strains to Epithelial Cells

A. Torres, J. Kaper, Xin Zhou, 2005, Infection and Immunity.

Strains to Epithelial Cells coli Escherichia Adherence of Diarrheagenic

A. Torres, J. Kaper, Xin Zhou, 2004 .

Identification and Characterization of lpfABCC DE , a Fimbrial Operon of Enterohemorrhagic Escherichia coli O 157 : H 7

F. Blattner, N. Perna, V. Burland, 2002 .

Vibrio cholerae produces a second enterotoxin, which affects intestinal tight junctions.

J. Kaper, A. Fasano, B. Tall, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Economic Analyses of Vaccines and Vaccination Programs

Rosanna Lagos, C. Weijer, R. Rappuoli, 2004 .

Antibiotic-Resistant Cell-Detaching Escherichia coli Strains from Nigerian Children

I. Okeke, J. Kaper, S. Elliott, 2002, Journal of Clinical Microbiology.

Enterotoxigenic Escherichia coli is phagocytosed by macrophages underlying villus-like intestinal epithelial cells: modeling ex vivo innate immune defenses of the human gut

M. Doucet, J. Nataro, N. Zachos, 2017, Gut microbes.

The Type III Effectors NleE and NleB from Enteropathogenic E. coli and OspZ from Shigella Block Nuclear Translocation of NF-κB p65

J. Whisstock, G. Holloway, M. Dunstone, 2010, PLoS pathogens.

The epidemiology, pathogenicity and microbiology of foodborne Escherichia coli O157:H7

J. Kaper, S. Joseph, D. Ingram, 2002 .

Overview and Historical Perspectives

J. Kaper, A. O’Brien, 2014, Microbiology spectrum.

Functional and Phylogenetic Analysis of ureD in Shiga Toxin-Producing Escherichia coli

D. Rasko, J. Kaper, Susan R. Steyert, 2010, Journal of bacteriology.

Characterization of the second long polar (LP) fimbriae of Escherichia coli O157:H7 and distribution of LP fimbriae in other pathogenic E. coli strains.

A. Torres, J. Kaper, V. Popov, 2004, FEMS microbiology letters.

Characterization of the second long polar (LP) fimbriae of Escherichia coli O157:H7 and distribution

A. Torres, J. Kaper, V. Popov, 2004 .

Escherichia coli Enteropathogenic and Enterohemorrhagic Non-LEE-Encoded Virulence Factors in Expression of Both LEE-and ( LEE )-Encoded Regulator Controls The Locus of Enterocyte Effacement

V. Sperandio, T. McDaniel, J. Kaper, 2000 .

Long Polar Fimbriae Contribute to Colonization by Escherichia coli O157:H7 In Vivo

A. Torres, J. Kaper, N. Cornick, 2004, Infection and Immunity.

Urease of Enterohemorrhagic Escherichia coli: Evidence for Regulation by Fur and a trans-Acting Factor

F. Blattner, N. Perna, G. Pósfai, 2002, Infection and Immunity.

Pathogenicity Islands and Other Mobile Genetic Elements of Diarrheagenic Escherichia coli

J. Nataro, J. Kaper, J. Mellies, 1999 .

Genomic diversity of EPEC associated with clinical presentations of differing severity

D. Rasko, M. Levine, T. Ramamurthy, 2016, Nature Microbiology.

EPEC delivers the goods.

J. Kaper, 1998, Trends in microbiology.

Plasmid-mediated factors conferring diffuse and localized adherence of enteropathogenic Escherichia coli

M. Levine, J. Nataro, J. Kaper, 1985, Infection and immunity.

A genetic locus of enteropathogenic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cells.

J. Yu, J. Kaper, B. Tall, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Detection of an adherence factor of enteropathogenic Escherichia coli with a DNA probe.

M. Levine, R. Black, J. Nataro, 1985, The Journal of infectious diseases.

Patterns of adherence of diarrheagenic Escherichia coli to HEp-2 cells.

M. Levine, J. Nataro, J. Kaper, 1987, The Pediatric infectious disease journal.

Gene encoding zonula occludens toxin (zot) does not occur independently from cholera enterotoxin genes (ctx) in Vibrio cholerae

J. Morris, J. Kaper, J. A. Johnson, 1993, Journal of clinical microbiology.

Two stages of enteropathogenic Escherichia coli intestinal pathogenicity are up and down-regulated by the epithelial cell differentiation

A. Barbat, S. Kernéis, J. Kaper, 1995, Differentiation.

In vivo bioluminescence imaging of Escherichia coli O104:H4 and role of aerobactin during colonization of a mouse model of infection

A. Torres, J. Kaper, M. Rojas-Lopez, 2012, BMC Microbiology.

Determination of spatial and temporal colonization of enteropathogenic E. coli and enterohemorrhagic E. coli in mice using bioluminescent in vivo imaging

J. Kaper, K. Rhee, G. Hecht, 2011, Gut microbes.

Calcium-dependent intestinal chloride secretion by Vibrio parahaemolyticus thermostable direct hemolysin in a rabbit model.

J. Kao, J. Kaper, A. Fasano, 1995, Gastroenterology.

An in vivo expression technology screen for Vibrio cholerae genes expressed in human volunteers

C. Tacket, A. Camilli, J. Nataro, 2007, Proceedings of the National Academy of Sciences.

New and Improved Vaccines Against Meningococcal Diseases 6 . AUTHOR (

J. Kaper, G. Woodrow, 2022 .

Cloning and sequencing of the genes encoding Escherichia coli cytolethal distending toxin

J. Kaper, D. Scott, Daniel A. SCOTTt, 1994, Infection and immunity.

Enteropathogenic Escherichia coli

J. Kaper, M. Donnenberg, Michael S. DONNENBERGl, 1992, Infection and immunity.

Background Paper on the Integration of Oral Cholera Vaccines into Global Cholera Control Programmes

Z. Bhutta, J. Kaper, D. Sur, 2009 .

PaxVax CVD 103-HgR single-dose live oral cholera vaccine

M. Levine, J. Kaper, Wilbur H. Chen, 2017, Expert review of vaccines.

Recombinant DNA risk assessment studies in humans: efficacy of poorly mobilizable plasmids in biologic containment.

M. Levine, R. Black, J. Kaper, 1983, The Journal of infectious diseases.

Cloning and characterization of the eae gene of enterohaemorrhagic Escherichia coli O157:H7

J. Yu, J. Kaper, 1992, Molecular microbiology.

Vibrio cholerae Flagellins Induce Toll-Like Receptor 5-Mediated Interleukin-8 Production through Mitogen-Activated Protein Kinase and NF-κB Activation

J. Kaper, Susan R. Steyert, J. Michalski, 2008, Infection and Immunity.

Second-Generation Recombination-Based In Vivo Expression Technology for Large-Scale Screening for Vibrio cholerae Genes Induced during Infection of the Mouse Small Intestine

A. Camilli, J. Kaper, J. Michalski, 2005, Infection and Immunity.

Vaccines against Vibrio cholerae

J. Kaper, J. Campbell, J. Campbell, 2003 .

Cloning, expression and characterization of the CHO cell elongating factor (Cef) from Vibrio cholerae O1.

M. Kothary, V. Sathyamoorthy, B. Mccardell, 2002, Microbial pathogenesis.

Investigation of the Roles of Toxin-Coregulated Pili and Mannose-Sensitive Hemagglutinin Pili in the Pathogenesis of Vibrio cholerae O139 Infection

M. Levine, C. Tacket, Y. Lim, 1998, Infection and Immunity.

Role of cholera toxin in enteric colonization by Vibrio cholerae O1 in rabbits

W. Cray, J. Mekalanos, J. Kaper, 1985, Infection and immunity.

New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development.

M. Levine, R. Black, J. Kaper, 1983, Microbiological reviews.

Vibrio parahaemolyticus and related halophilic Vibrios.

R. Colwell, J. Kaper, S. Joseph, 1982, Critical reviews in microbiology.

Complete Nucleotide Sequence and Analysis of the Locus of Enterocyte Effacement from Rabbit Diarrheagenic Escherichia coli RDEC-1

E. Boedeker, J. Kaper, S. Elliott, 2001, Infection and Immunity.

11 – Cholera vaccines

C. Tacket, J. Kaper, J. Clemens, 2013 .

Shiga toxin binding in normal and inflamed human intestinal mucosa.

J. Kaper, F. Torrente, R. Heuschkel, 2007, Microbes and infection.

Intestinal Mucin Inhibits Adhesion of Human Enteropathogenic Escherichia coli to HEp‐2 Cells

J. Kaper, D. Mack, C. Smith, 1995, Journal of pediatric gastroenterology and nutrition.

Prevalence and association of the longus pilus structural gene (lngA) with colonization factor antigens, enterotoxin types, and serotypes of enterotoxigenic Escherichia coli

V. Sperandio, D. Maneval, M. Levine, 1995, Infection and immunity.

Enterohemorrhagic Escherichia coli.

J. Kaper, 1998, Current opinion in microbiology.

Role of Shiga toxin versus H7 flagellin in enterohaemorrhagic Escherichia coli signalling of human colon epithelium in vivo

M. Kagnoff, A. Torres, J. Kaper, 2006, Cellular microbiology.

A second chromosomal gene necessary for intimate attachment of enteropathogenic Escherichia coli to epithelial cells

J. Yu, J. Kaper, M. Donnenberg, 1993, Journal of bacteriology.

Genetic Diversity of the Gene Cluster Encoding Longus, a Type IV Pilus of Enterotoxigenic Escherichia coli

E. Sokurenko, J. Kaper, S. Chattopadhyay, 2007, Journal of bacteriology.

Nucleotide Sequence Analysis of the Enteropathogenic Escherichia coli Adherence Factor Plasmid pMAR 7 ‡

F. Blattner, V. Burland, D. Rose, 2006 .

Monoclonal antibodies specific for the bundle-forming pilus of enteropathogenic Escherichia coli

J. Kaper, M. Albert, J. Girón, 1995, Infection and immunity.

Distribution of the bundle-forming pilus structural gene (bfpA) among enteropathogenic Escherichia coli.

K. Jarvis, J. Kaper, M. Donnenberg, 1993, The Journal of infectious diseases.

Use of DNA probes and HEp-2 cell adherence assay to detect diarrheagenic Escherichia coli.

M. Levine, H. Lior, J. Nataro, 1988, The Journal of infectious diseases.

Characterization of plasmids encoding the adherence factor of enteropathogenic Escherichia coli

J. Nataro, J. Kaper, K. Maher, 1987, Infection and immunity.

Plasmid‐Mediated Adhesion in Enteropathogenic Escherichia coli

M. Levine, J. Kaper, D. Candy, 1983, Journal of pediatric gastroenterology and nutrition.

Attaching and effacing of host cells by enteropathogenic Escherichia coli in the absence of detectable tyrosine kinase mediated signal transduction.

T. McDaniel, K. Jarvis, K. Stone, 1996, Microbial pathogenesis.

Editorial: Infection and immunity research at the University of Maryland, Baltimore.

M. Flajnik, H. Mobley, J. Kaper, 2016, Pathogens and disease.

EspB and EspD require a specific chaperone for proper secretion from enteropathogenic Escherichia coli

J. Kaper, L. Wainwright, James B. Kaper, 1998, Molecular microbiology.

Enteropathogenic Escherichia coli decreases the transepithelial electrical resistance of polarized epithelial monolayers

B. Finlay, C. Canil, J. Kaper, 1993, Infection and immunity.

Enteropathogenic Escherichia coli EspG disrupts microtubules and in conjunction with Orf3 enhances perturbation of the tight junction barrier

J. Kaper, V. Viswanathan, G. Hecht, 2005, Molecular microbiology.

Enteropathogenic Escherichia coli.

J. Kaper, M. Donnenberg, 1992 .

Role of plasmid-encoded adherence factors in adhesion of enteropathogenic Escherichia coli to HEp-2 cells

J. Kaper, M. Baldini, S. Knutton, 1987, Infection and immunity.

Identification of IngA, the structural gene of longus type IV pilus of enterotoxigenic Escherichia coli

K. Jarvis, G. Viboud, J. Kaper, 1999 .

SepL, a protein required for enteropathogenic Escherichia coli type III translocation, interacts with secretion component SepD

J. Kaper, M. Albert, M. Donnenberg, 2004, Molecular microbiology.

A Gene from the Locus of Enterocyte Effacement That Is Required for Enteropathogenic Escherichia coli To Increase Tight-Junction Permeability Encodes a Chaperone for EspF

J. Kaper, M. Donnenberg, G. Hecht, 2002, Infection and Immunity.

EspG, a Novel Type III System-Secreted Protein from Enteropathogenic Escherichia coli with Similarities to VirA of Shigella flexneri

C. Sasakawa, J. Kaper, J. Mellies, 2001, Infection and Immunity.

Antibodies to intimin and Escherichia coli secreted proteins A and B in patients with enterohemorrhagic Escherichia coli infections

L. Gansheroff, K. Jarvis, J. Kaper, 2002, Pediatric Nephrology.

LEE-encoded regulator (Ler) mutants elicit serotype-specific protection, but not cross protection, against attaching and effacing E. coli strains.

E. Boedeker, J. Kaper, S. Feng, 2007, Vaccine.

Towards a vaccine for attaching/effacing Escherichia coli: a LEE encoded regulator (ler) mutant of rabbit enteropathogenic Escherichia coli is attenuated, immunogenic, and protects rabbits from lethal challenge with the wild-type virulent strain.

E. Boedeker, J. Kaper, S. Feng, 2006, Vaccine.

Enteropathogenic Escherichia coliVirulence Genes Encoding Secreted Signalling Proteins Are Essential for Modulation of Caco-2 Cell Electrolyte Transport

J. Kaper, M. Donnenberg, S. Knutton, 1998, Infection and Immunity.

Cloning of the RDEC-1 locus of enterocyte effacement (LEE) and functional analysis of the phenotype on HEp-2 cells.

T. McDaniel, E. Boedeker, J. Kaper, 1997, Advances in experimental medicine and biology.

Protective immunity to Shiga-like toxin I following oral immunization with Shiga-like toxin I B-subunit-producing Vibrio cholerae CVD 103-HgR

M. Levine, D. Acheson, G. Keusch, 1996, Infection and immunity.

Diffuse-adhering Escherichia coli (DAEC) as a putative cause of diarrhea in Mayan children in Mexico.

J. Kaper, S. Moseley, G. Frankel, 1991, The Journal of infectious diseases.

Development of a live oral attaching and effacing Escherichia coli vaccine candidate using Vibrio cholerae CVD 103-HgR as antigen vector.

E. Boedeker, J. Kaper, R. Keller, 2010, Microbial pathogenesis.

Molecular and ultrastructural characterisation of EspA from different enteropathogenic Escherichia coli serotypes

V. Sperandio, G. Dougan, J. Kaper, 1998 .

The ex vivo response of human intestinal mucosa to enteropathogenic Escherichia coli infection

J. Kaper, S. Schüller, A. Phillips, 2009, Cellular microbiology.

Localization of a determinant for HEp-2 adherence by enteropathogenic Escherichia coli

J. Nataro, J. Kaper, M. Baldini, 1986, Infection and immunity.

Characterization of Escherichia coliStrains from Cases of Childhood Diarrhea in Provincial Southwestern Nigeria

I. Okeke, J. Kaper, A. Lamikanra, 2000, Journal of Clinical Microbiology.

Characterization of the locus of enterocyte effacement (LEE) in different enteropathogenic Escherichia coli (EPEC) and Shiga-toxin producing Escherichia coli (STEC) serotypes.

V. Sperandio, J. Kaper, B. Neves, 1998, FEMS microbiology letters.

Controlled study of cytolethal distending toxin-producing Escherichia coli infections in Bangladeshi children

A. Faruque, S. Faruque, J. Kaper, 1996, Journal of clinical microbiology.

Oligonucleotide probe for detection of the enteropathogenic Escherichia coli (EPEC) adherence factor of localized adherent EPEC

J. Kaper, J. Galen, A. Jerse, 1990, Journal of clinical microbiology.

putative type III secretion system. enterohemorrhagic Escherichia coli via a Secretion of extracellular proteins by

K. Jarvis, J. Kaper, 2013 .

The locus of enterocyte effacement pathogenicity island of Shiga toxin-producing Escherichia coli O157:H7 and other attaching and effacing E. coli.

J. Kaper, 1998, Japanese journal of medical science & biology.

B. Finlay, J. Kaper, I. Rosenshine, 1992 .

Enteropathogenic Escherichia coli Strain RDEC-1 Produces a Novel Electrogenic Factor Active on Rabbit Ileum In Vitro

M. Wolf, E. Boedeker, J. Kaper, 2001, Journal of pediatric gastroenterology and nutrition.

The lpf Gene Cluster for Long Polar Fimbriae Is Not Involved in Adherence of Enteropathogenic Escherichia coli or Virulence of Citrobacter rodentium

A. Torres, I. Tatsuno, J. Kaper, 2006, Infection and Immunity.

Heterogeneous virulence of enteroaggregative Escherichia coli strains isolated from children in Southwest Nigeria.

I. Okeke, J. Nataro, J. Kaper, 2000, The Journal of infectious diseases.

A sensitive and specific DNA probe to identify enteroaggregative Escherichia coli, a recently discovered diarrheal pathogen.

M. Levine, J. Kaper, P. Vial, 1990, The Journal of infectious diseases.

The continuing evolution of a bacterial pathogen

J. Kaper, M. Karmali, 2008, Proceedings of the National Academy of Sciences.

Construction of genetically marked Vibrio cholerae O1 vaccine strains.

M. Levine, J. Kaper, J. Michalski, 1993, FEMS microbiology letters.

Practical and economical method for using biotinylated DNA probes with bacterial colony blots to identify diarrhea-causing Escherichia coli

M. Levine, J. Kaper, M. Baldini, 1990, Journal of clinical microbiology.

Enterohemorrhagic Escherichia coli Reduces Mucus and Intermicrovillar Bridges in Human Stem Cell-Derived Colonoids

M. Halushka, M. Estes, M. Donowitz, 2015, Cellular and molecular gastroenterology and hepatology.

Effect on Human Cells of Environmental Vibrio parahaemolyticus Strains Carrying Type III Secretion System 2

R. Colwell, A. Huq, J. Kaper, 2010, Infection and Immunity.

Enterotoxigenicity of Vibrio parahaemolyticus with and without genes encoding thermostable direct hemolysin

R. Russell, J. Kaper, M. Nishibuchi, 1992, Infection and immunity.

Cloning of the thermostable direct or Kanagawa phenomenon-associated hemolysin of Vibrio parahaemolyticus

J. Kaper, S. Falkow, R. Seidler, 1984, Infection and immunity.

Chromosomal and Plasmid-Encoded Factors of Shigella flexneri Induce Secretogenic Activity Ex Vivo

J. Nataro, J. Kaper, A. Fasano, 2012, PloS one.

Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion

J. Kaper, C. Sears, 1996 .

Identification and characterization of "pathoadaptive mutations" of the cadBA operon in several intestinal Escherichia coli.

A. Torres, L. Wieler, J. Kaper, 2006, International journal of medical microbiology : IJMM.

Enzyme-Linked Immunosorbent Assay for Detection of Shiga Toxin-Producing Escherichia coli Infection by Antibodies to Escherichia coli Secreted Protein B in Children with Hemolytic Uremic Syndrome

A. Caprioli, J. Kaper, D. Karpman, 2004, European Journal of Clinical Microbiology and Infectious Diseases.

Mucosal Immune Profiles Associated with Diarrheal Disease Severity in Shigella- and Enteropathogenic Escherichia coli-Infected Children Enrolled in the Global Enteric Multicenter Study

W. Blackwelder, J. Nataro, J. Kaper, 2022, mBio.

HeLa cell adherence and cytotoxin production by enteropathogenic Escherichia coli isolated from infants with diarrhea in Thailand

G. Keusch, J. Kaper, P. Echeverria, 1987, Journal of clinical microbiology.

Colonization of Gnotobiotic Piglets by a luxS Mutant Strain of Escherichia coli O157:H7

V. Sperandio, J. Kaper, H. Moon, 2005, Infection and Immunity.

ENTEROAGGREGATIVE ESCHERICHIA COLI, A NEW DIARRHEAL AGENT

M. Levine, J. Kaper, P. Vial, 1991 .

Enteropathogenic Escherichia coli EspH-Mediated Rho GTPase Inhibition Results in Desmosomal Perturbations

J. Kaper, V. Viswanathan, G. Vedantam, 2018, Cellular and molecular gastroenterology and hepatology.

A novel locus of enterocyte effacement (LEE) pathogenicity island inserted at pheV in bovine Shiga toxin-producing Escherichia coli strain O103:H2.

L. Wieler, J. Kaper, J. Jores, 2001, FEMS microbiology letters.

HeLa cell-adherent Escherichia coli in children with diarrhea in Thailand.

J. Kaper, P. Echeverria, D. N. Taylor, 1987, The Journal of infectious diseases.

Virulence Properties of Shiga Toxin-Producing Escherichia coli (STEC) Strains of Serogroup O118, a Major Group of STEC Pathogens in Calves

L. Wieler, J. Kaper, G. Baljer, 1998, Journal of Clinical Microbiology.

Etiology of Acute Diarrhea in Adults in Southwestern Nigeria

I. Okeke, J. Kaper, A. Lamikanra, 2003, Journal of Clinical Microbiology.

Colonization factor antigens I and II and type 1 somatic pili in enterotoxigenic Escherichia coli: relation to enterotoxin type

M. Levine, R. Sack, J. Kaper, 1983, Infection and immunity.

Pathogenicity islands and other mobile virulence elements

J. Hacker, J. Kaper, 1999 .

Shuttle cloning vectors for the marine bacterium Vibrio parahaemolyticus

J. Kaper, A. Datta, A. MacQuillan, 1984, Journal of bacteriology.

Direct Hemolysin in Vibrio cholerae Non-Ol Strains

Toshio, J. Kaper, M. Nishibuchi, 2003 .

Comparative analysis of the hemolysin genes of Vibrio cholerae non-01, V. mimicus, and V. hollisae that are similar to the tdh gene of V. parahaemolyticus.

J. Kaper, M. Nishibuchi, T. Honda, 1990, FEMS microbiology letters.

Transposon-induced non-motile mutants of Vibrio cholerae.

J. Kaper, J. Michalski, K. Richardson, 1990, Journal of general microbiology.

Effects of DNase production, plasmid size, and restriction barriers on transformation of Vibrio cholerae by electroporation and osmotic shock.

J. Kaper, R. Holmes, H. Marcus, 1990, FEMS microbiology letters.

Molecular cloning and transcriptional regulation of ompT, a ToxR‐repressed gene in Vibrio cholerae

V. DiRita, J. Kaper, J. A. Crawford, 2000, Molecular microbiology.

Cloning and characterization of the gene encoding the OmpU outer membrane protein of Vibrio cholerae

V. Sperandio, V. DiRita, J. Kaper, 1996, Infection and immunity.

Use of stabilized luciferase-expressing plasmids to examine in vivo-induced promoters in the Vibrio cholerae vaccine strain CVD 103-HgR.

J. Kaper, Cara E. Morin, 2009, FEMS immunology and medical microbiology.

Useof stabilized luciferase-expressing plasmids to examine invivo-induced promoters in theVibrio choleraevaccine strainCVD 103-HgR

J. Kaper, Cara E. Morin, 2009 .

Safety and immunogenicity of live oral cholera vaccine candidate CVD 110, a delta ctxA delta zot delta ace derivative of El Tor Ogawa Vibrio cholerae.

M. Levine, C. Tacket, G. Losonsky, 1993, Journal of Infectious Diseases.

Molecular epidemiology of group JK Corynebacterium on a cancer ward: lack of evidence for patient-to-patient transmission.

R. Khabbaz, J. Tenney, J. Kaper, 1986, The Journal of infectious diseases.

Cloning of a gene involved in regulation of exotoxin A expression in Pseudomonas aeruginosa

D. Galloway, J. Kaper, C. Funk, 1986, Infection and immunity.

Simultaneous expression of CFA/I and CS3 colonization factor antigens of enterotoxigenic Escherichia coli by delta aroC, delta aroD Salmonella typhi vaccine strain CVD 908.

M. Levine, J. Kaper, J. Girón, 1995, Vaccine.

Conserved sequences in bacterial and viral sialidases

E. Vimr, J. Kaper, J. Galen, 2005, Glycoconjugate Journal.

Cloning of a gene (zot) encoding a new toxin produced by Vibrio cholerae

J. Kaper, A. Fasano, J. Ketley, 1992, Infection and immunity.

Hemolysin production and cloning of two hemolysin determinants from classical Vibrio cholerae

J. Kaper, J. Michalski, K. Richardson, 1986, Infection and immunity.

New Generation Vaccines, 3rd Edition

R. Rappuoli, M. Levine, M. Dekker, 2004 .

Identification of a 33 kDa antigen associated with an adhesive and colonizing strain of Vibrio cholerae El Tor and its role in protection.

J. Kaper, B. S. Srivastava, R. Srivastava, 1993, Vaccine.

Identification of the flagellar antigens of Vibrio cholerae El Tor and their role in protection.

J. Kaper, B. S. Srivastava, R. Srivastava, 1993, Vaccine.

Synthetic oligodeoxyribonucleotide probes to detect Kanagawa phenomenon-positive Vibrio parahaemolyticus

W. L. Payne, G. Zon, J. Kaper, 1986, Journal of clinical microbiology.

Development and testing of a synthetic oligonucleotide probe for the detection of pathogenic Yersinia strains

M. Miliotis, J. Morris, J. Kaper, 1989, Journal of clinical microbiology.

Live oral vaccines against cholera: an update.

M. Levine, J. Kaper, 1993, Vaccine.

Production of Vibrio cholerae accessory cholera enterotoxin (Ace) in the yeast Pichia pastoris

J. Kaper, A. Fasano, M. Trucksis, 1997, Infection and immunity.

CVD110, an attenuated Vibrio cholerae O1 El Tor live oral vaccine strain

J. Kaper, J. Michalski, A. Fasano, 1993, Infection and immunity.

Identification of enteric pathogens in the small and large intestine of children with diarrhea.

J. Nataro, J. Kaper, P. Echeverria, 1986, Diagnostic microbiology and infectious disease.

Duplication and variation of the thermostable direct haemolysin (tdh) gene in Vibrio parahaemolyticus

J. Kaper, M. Nishibuchi, 1990, Molecular microbiology.

Mechanism of toxin secretion by Vibrio cholerae investigated in strains harboring plasmids that encode heat-labile enterotoxins of Escherichia coli.

J. Kaper, J. Holmgren, T. Hirst, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Identification of a Group 1-Like Capsular Polysaccharide Operon for Vibrio vulnificus

J. Morris, A. Wright, J. Kaper, 2001, Infection and Immunity.

Numerical taxonomy of Vibrio cholerae and related species isolated from areas that are endemic and nonendemic for cholera

R. Colwell, J. Kaper, S. De, 1983, Journal of clinical microbiology.

Diminished immunogenicity of a recombination-deficient derivative of Vibrio cholerae vaccine strain CVD103

M. Levine, G. Losonsky, J. Kaper, 1990, Infection and immunity.

Multiple Elements Controlling Adherence of Enterohemorrhagic Escherichia coli O157:H7 to HeLa Cells

A. Torres, J. Kaper, James B. Kaper, 2003, Infection and Immunity.

StcE, a metalloprotease secreted by Escherichia coli O157:H7, specifically cleaves C1 esterase inhibitor

W. W. Lathem, A. Torres, J. Kaper, 2002, Molecular microbiology.

Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion.

J. Kaper, C. Sears, 1996, Microbiological reviews.

Numerical taxonomy ofKlebsiella pneumoniae strains isolated from clinical and nonclinical sources

R. Colwell, J. Kaper, R. Seidler, 1979, Current Microbiology.

Nucleotide sequence of the thermostable direct hemolysin gene of Vibrio parahaemolyticus

J. Kaper, M. Nishibuchi, 1985, Journal of bacteriology.

Aeromonas hydrophila: ecology and toxigenicity of isolates from an estuary.

R. Colwell, J. Kaper, H. Lockman, 1981, The Journal of applied bacteriology.

Isolation of drug-resistant Aeromonas hydrophila from aquatic environments

R. Colwell, E. Remmers, J. Kaper, 1980, Antimicrobial Agents and Chemotherapy.

Escherichia, Shigella, and Salmonella

P. Fields, J. Nataro, J. Kaper, 2011 .

Detection of the thermostable direct hemolysin gene and related DNA sequences in Vibrio parahaemolyticus and other vibrio species by the DNA colony hybridization test

Y. Takeda, J. Kaper, M. Nishibuchi, 1985, Infection and immunity.

Contribution of the tdh1 gene of Kanagawa phenomenon-positive Vibrio parahaemolyticus to production of extracellular thermostable direct hemolysin.

J. Kaper, M. Nishibuchi, K. Kumagai, 1991, Microbial pathogenesis.

Role of Vibrio cholerae neuraminidase in the function of cholera toxin

J. Kaper, A. Fasano, J. Galen, 1992, Infection and immunity.

Ambient-temperature primary nonselective enrichment for isolation of Salmonella spp. from an estuarine environment

G. Sayler, R. Colwell, J. Kaper, 1977, Applied and environmental microbiology.

GeneEncoding ZonulaOccludens Toxin(zot) DoesNot OccurIndependently fromCholera Enterotoxin Genes(ctx) inVibrio cholerae

J. Morris, J. Kaper, 1993 .

Escherichia, Shigella, and Salmonella

P. Fields, J. Nataro, J. Kaper, 2020, Color Atlas of Medical Bacteriology.

Cholera

M. Levine, J. Morris, J. Kaper, 1884, Clinical microbiology reviews.

Molecular Genetics of Bacterial Pathogenesis

D. Portnoy, J. Kaper, R. Isberg, 1994 .

Cloning and expression of the Vibrio cholerae neuraminidase gene nanH in Escherichia coli

E. Vimr, J. Kaper, J. Galen, 1988, Journal of bacteriology.

Identification of CesT, a chaperone for the type III secretion of Tir in enteropathogenic Escherichia coli

J. Kaper, J. Mellies, M. Batchelor, 1999, Molecular microbiology.

Pathogenicity Islands and the Evolution of Pathogenic Microbes

J. Hacker, J. Kaper, 2002, Current Topics in Microbiology and Immunology.

Determinants of the immunogenicity of live virulent and mutant Vibrio cholerae O1 in rabbit intestine

W. Cray, J. Mekalanos, J. Kaper, 1987, Infection and immunity.

Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli.

V. Sperandio, J. Kaper, J. Mellies, 1999, Proceedings of the National Academy of Sciences of the United States of America.

The Vibrio cholerae genome contains two unique circular chromosomes.

J. Kaper, J. Michalski, M. Trucksis, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Longus: a long pilus ultrastructure produced by human enterotoxigenic Escherichia coli

M. Levine, J. Kaper, J. Girón, 1994, Molecular microbiology.

The flagella of enteropathogenic Escherichia coli mediate adherence to epithelial cells

A. Torres, J. Kaper, E. Freer, 2002, Molecular microbiology.

The Escherichia coli Phosphotyrosine Proteome Relates to Core Pathways and Virulence

Nandini A. Sahasrabuddhe, A. Emili, A. Pandey, 2013, PLoS pathogens.

The diarrheal response of humans to some classic serotypes of enteropathogenic Escherichia coli is dependent on a plasmid encoding an enteroadhesiveness factor.

M. Levine, H. Karch, R. Black, 1985, The Journal of infectious diseases.

Hfq affects the expression of the LEE pathogenicity island in enterohaemorrhagic Escherichia coli

J. Kaper, A. Hansen, 2009, Molecular microbiology.

Coronin-1 is necessary for enteric pathogen-induced transcytosis across human ileal enteroid monolayers expressing M cells

M. Estes, M. Doucet, N. Zachos, 2020, bioRxiv.

Randomized, Double-Blind, Placebo-Controlled, Multicentered Trial of the Efficacy of a Single Dose of Live Oral Cholera Vaccine CVD 103-HgR in Preventing Cholera following Challenge with Vibrio cholerae O1 El Tor Inaba Three Months after Vaccination

M. Levine, C. Tacket, J. Kaper, 1999, Infection and Immunity.

Bacterial Cell-to-Cell Signaling in the Gastrointestinal Tract

Vanessa Sperandio, V. Sperandio, J. Kaper, 2005, Infection and Immunity.

Diarrheagenic Escherichia coli

J. Nataro, J. Kaper, 1998, Clinical Microbiology Reviews.

Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection

M. Donowitz, Jennifer Foulke-Abel, J. Kaper, 2020, Gut microbes.

The presence of the pAA plasmid in the German O104:H4 Shiga toxin type 2a (Stx2a)-producing enteroaggregative Escherichia coli strain promotes the translocation of Stx2a across an epithelial cell monolayer.

Anne-Marie Hansen, J. Nataro, J. Kaper, 2014, The Journal of infectious diseases.

Bacteria–host communication: The language of hormones

Vanessa Sperandio, James P. Nataro, V. Sperandio, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Comparative Genomics Provides Insight into the Diversity of the Attaching and Effacing Escherichia coli Virulence Plasmids

D. Rasko, J. Nataro, J. Kaper, 2015, Infection and Immunity.

Chimeric Vaccines Against Japanese Encephalitis, Dengue, and West Nile

F. Guirakhoo, T. Monath, R. Rappuoli, 2004 .

Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two‐component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli

Vanessa Sperandio, V. Sperandio, A. Torres, 2002, Molecular microbiology.

Renaming protein secretion in the gram-negative bacteria.

B. Finlay, I. Henderson, J. Nataro, 2000, Trends in microbiology.

Association of Genomic O Island 122 of Escherichia coli EDL 933 with Verocytotoxin-Producing Escherichia coli Seropathotypes That Are Linked to Epidemic and/or Serious Disease

J. Kaper, C. Clark, J. Isaac-Renton, 2003, Journal of Clinical Microbiology.

Commensal and pathogenic Escherichia coli use a common pilus adherence factor for epithelial cell colonization

J. Kaper, J. Puente, María A Rendón, 2007, Proceedings of the National Academy of Sciences.

A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens.

T. McDaniel, K. Jarvis, J. Kaper, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of interactions of enteropathogenic Escherichia coli O127:H6 with mammalian cells in vitro.

S. Falkow, J. Kaper, A. Jerse, 1991, The Journal of infectious diseases.

An outbreak of foodborne illness caused by Escherichia coli O39:NM, an agent not fitting into the existing scheme for classifying diarrheogenic E. coli.

J. Besser, M. Osterholm, T. Barrett, 1997, The Journal of infectious diseases.

A plasmid‐encoded type IV fimbrial gene of enteropathogenic Escherichia coli associated with localized adherence

J. Nataro, J. Kaper, M. Donnenberg, 1992, Molecular microbiology.

The ToxR-Mediated Organic Acid Tolerance Response of Vibrio cholerae Requires OmpU

A. Camilli, J. Kaper, D. Merrell, 2001, Journal of bacteriology.

Comparison of Vibrio choleraePathogenicity Islands in Sixth and Seventh Pandemic Strains

J. Kaper, P. Reeves, R. Lan, 2001, Infection and Immunity.

A bacteriophage encoding a pathogenicity island, a type-IV pilus and a phage receptor in cholera bacteria

D. Maneval, J. Kaper, Judith A. Johnson, 1999, Nature.

SepZ/EspZ Is Secreted and Translocated into HeLa Cells by the Enteropathogenic Escherichia coli Type III Secretion System

I. Tatsuno, J. Kaper, M. Karmali, 2005, Infection and Immunity.

Pathogenic Escherichia coli.

H. Mobley, J. Nataro, J. Kaper, 2005, Nature reviews. Microbiology.

The N‐terminus of enteropathogenic Escherichia coli (EPEC) Tir mediates transport across bacterial and eukaryotic cell membranes

J. Kaper, James B Kaper, J. A. Crawford, 2002, Molecular microbiology.

Descriptive epidemiology of persistent diarrhoea among young children in rural northern India.

M. Levine, J. Kaper, S. Sazawal, 1989, Bulletin of the World Health Organization.

ToxR interferes with CRP‐dependent transcriptional activation of ompT in Vibrio cholerae

A. Camilli, J. Kaper, D. Merrell, 2002, Molecular microbiology.

Analysis of ToxR‐dependent transcription activation of ompU, the gene encoding a major envelope protein in Vibrio cholerae

V. DiRita, J. Kaper, J. A. Crawford, 1998, Molecular microbiology.

Ecology, serology, and enterotoxin production of Vibrio cholerae in Chesapeake Bay

R. Colwell, J. Kaper, H. Lockman, 1979, Applied and environmental microbiology.

Pediatric diarrhea: the challenge of prevention

M. Rennels, M. Levine, J. Morris, 1986, Pediatric infectious disease.

Zonula occludens toxin modulates tight junctions through protein kinase C-dependent actin reorganization, in vitro.

C. Fiorentini, G. Donelli, X. Ding, 1995, The Journal of clinical investigation.

The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69

T. McDaniel, K. Jarvis, B. P. McNamara, 1998 .

Molecular Evolution of a Pathogenicity Island from Enterohemorrhagic Escherichia coli O157:H7

Nicole T. Perna, Frederick R. Blattner, F. Blattner, 1998, Infection and Immunity.

Phosphotyrosine-Mediated Regulation of Enterohemorrhagic Escherichia coli Virulence

D. Rasko, J. Kaper, A. Hansen, 2018, mBio.

The eae gene of enteropathogenic Escherichia coli encodes a 94-kilodalton membrane protein, the expression of which is influenced by the EAF plasmid

J. Kaper, A. Jerse, 1991, Infection and immunity.

Mechanical Stimuli Affect Escherichia coli Heat-Stable Enterotoxin-Cyclic GMP Signaling in a Human Enteroid Intestine-Chip Model

M. Donowitz, Jianyi Yin, J. Kaper, 2019, Infection and Immunity.

Mechanical Stimuli Affect E. Coli Heat Stable Enterotoxin (ST)-Cyclic GMP Signaling in a Human Enteroid Intestine-Chip Diarrhea Model

M. Donowitz, Jianyi Yin, J. Kaper, 2019, bioRxiv.

Vibrios in the Louisiana gulf coast environment

J. Kaper, H. Bradford, N. Roberts, 1982, Microbial Ecology.

Evaluation of a bivalent (CVD 103-HgR/CVD 111) live oral cholera vaccine in adult volunteers from the United States and Peru

M. Levine, C. Tacket, G. Losonsky, 1997, Infection and immunity.

Genome plasticity in pathogenic and nonpathogenic enterobacteria.

J. Hacker, U. Dobrindt, U. Hentschel, 2002, Current topics in microbiology and immunology.

Anaerobic breakdown processes of organic matter in freshwater sediments

J. Miles, J. Kaper, E. Jongejans, 1978 .

Functional analysis of the enteropathogenic Escherichia coli type III secretion system chaperone CesT identifies domains that mediate substrate interactions

J. Kaper, G. Frankel, S. Knutton, 2002, Molecular microbiology.

Intestinal adherence associated with type IV pili of enterohemorrhagic Escherichia coli O157:H7.

J. Kaper, J. Puente, J. Xicohtencatl-Cortes, 2007, The Journal of clinical investigation.

Association of rns homologs with colonization factor antigens in clinical Escherichia coli isolates

D. Maneval, J. Kaper, J. Caron, 1990, Infection and immunity.

Activation of enteropathogenic Escherichia coli (EPEC) LEE2 and LEE3 operons by Ler

V. Sperandio, J. Kaper, J. Mellies, 2000, Molecular microbiology.

DISTRIBUTION, SURVIVAL, AND SIGNIFICANCE OF PATHOGENIC BACTERIA AND VIRUSES IN ESTUARIES

J. Kaper, R. Colwell, 1978 .

Vibrio species as bacterial indicators of potential health hazards associated with water

J. Kaper, R. Colwell, 1977 .

Morphological studies on fimbriae expressed by Vibrio cholerae 01.

M. Levine, J. Mekalanos, J. Kaper, 1988, Microbial pathogenesis.

The OmpU outer membrane protein, a potential adherence factor of Vibrio cholerae

V. Sperandio, J. Kaper, J. Girón, 1995, Infection and immunity.

Accessory cholera enterotoxin (Ace), the third toxin of a Vibrio cholerae virulence cassette.

J. Kaper, J. Michalski, A. Fasano, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Volunteer studies investigating the safety and efficacy of live oral El Tor Vibrio cholerae O1 vaccine strain CVD 111.

M. Levine, C. Tacket, G. Losonsky, 1997, The American journal of tropical medicine and hygiene.

Onset and duration of protective immunity in challenged volunteers after vaccination with live oral cholera vaccine CVD 103-HgR.

M. Levine, C. Tacket, G. Losonsky, 1992, The Journal of infectious diseases.

recA mutations reduce adherence and colonization by classical and El Tor strains of Vibrio cholerae.

K. Kumar, J. Kaper, B. S. Srivastava, 1994, Microbiology.

Oral Cholera Vaccines

J. Kaper, J. Holmgren, 1986, The Lancet.

Vibriocidal antibody responses in North American volunteers exposed to wild-type or vaccine Vibrio cholerae O139: specificity and relevance to immunity

M. Levine, C. Tacket, G. Losonsky, 1997, Clinical and diagnostic laboratory immunology.

Human immune response to Vibrio cholerae O1 whole cells and isolated outer membrane antigens

M. Levine, J. Kaper, M M Levine, 1989, Infection and immunity.

Recombinant attenuated Vibrio cholerae strains used as live oral vaccines.

M. Levine, J. Kaper, 1990, Research in microbiology.

Safety, immunogenicity, and excretion pattern of single-dose live oral cholera vaccine CVD 103-HgR in Peruvian adults of high and low socioeconomic levels

G. Losonsky, M. Penny, J. Kaper, 1993, Infection and immunity.

Toxin profiles of Vibrio cholerae non-O1 from environmental sources in Calcutta, India

Y. Takeda, G. Nair, J. Kaper, 1988, Applied and environmental microbiology.

Ambient-Temperature Primary Nonselective Enrichment for Isolation ofSalmonella

G. Sayler, J. Kaper, R. Colwell, 2022 .

Initial clinical studies of CVD 112 Vibrio cholerae O139 live oral vaccine: safety and efficacy against experimental challenge.

M. Levine, C. Tacket, G. Losonsky, 1995, The Journal of infectious diseases.

Role of the eaeA gene in experimental enteropathogenic Escherichia coli infection.

M. Levine, C. Tacket, G. Losonsky, 1993, The Journal of clinical investigation.

R-factor carriage in a group F vibrio isolated from Bangladesh

R. Colwell, E. Remmers, J. Kaper, 1980, Antimicrobial Agents and Chemotherapy.

Vibrio cholerae enterotoxin genes: nucleotide sequence analysis of DNA encoding ADP-ribosyltransferase

J. Kaper, H. Lockman, J. Galen, 1984, Journal of bacteriology.

Transcriptional Responses of Intestinal Epithelial Cells to Infection with Vibrio cholerae

S. Meltzer, J. Kaper, Xin Zhou, 2004, Infection and Immunity.

Cholera vaccines.

C. Tacket, J. Kaper, J. Clemens, 1992, Biotechnology.

The possible influence of LuxS in the in vivo virulence of rabbit enteropathogenic Escherichia coli.

E. Boedeker, J. Kaper, S. Feng, 2007, Veterinary microbiology.

The significance of Vibrio cholerae in the United States

M. Levine, J. Kaper, 1981 .

Vibrios in the Louisiana gulf coast environment

J. Kaper, H. Bradford, N. Roberts, 2005, Microbial Ecology.

Safety and immunogenicity of a booster dose of Vibrio cholerae CVD 103-HgR live oral cholera vaccine in Swiss adults

M. Levine, G. Losonsky, J. Kaper, 1992, Infection and immunity.

Demonstration of a plasmid-borne gene encoding a thermostable direct hemolysin in Vibrio cholerae non-O1 strains

J. Kaper, M. Nishibuchi, T. Honda, 1986, Applied and environmental microbiology.

Randomized double-blind placebo controlled trial to evaluate the safety and immunogenicity of the live oral cholera vaccine strain CVD 103-HgR in Swiss adults.

M. Levine, J. Kaper, S. Cryz, 1990, Vaccine.

Enteropathogenic Escherichia coli contains a putative type III secretion system necessary for the export of proteins involved in attaching and effacing lesion formation.

T. McDaniel, K. Jarvis, J. Kaper, 1995, Proceedings of the National Academy of Sciences of the United States of America.

RNA-Seq analysis of isolate- and growth phase-specific differences in the global transcriptomes of enteropathogenic Escherichia coli prototype isolates

D. Rasko, S. Daugherty, A. Shetty, 2015, Front. Microbiol..

A Medium for Presumptive Identification of Vibrio parahaemolyticus.

R. Colwell, E. Remmers, J. Kaper, 1980, Journal of food protection.

Quorum Sensing Is a Global Regulatory Mechanism in Enterohemorrhagic Escherichia coli O157:H7

Vanessa Sperandio, V. Sperandio, A. Torres, 2001, Journal of bacteriology.

Simultaneous expression of CFA/I and CS3 colonization factor antigens of enterotoxigenic Escherichia coli by ΔaroC, ΔaroD Salmonella typhi vaccine strain CVD 908

M. Levine, J. Kaper, Jian‐guo Xu, 1995 .

CHAPTER 12 – The LEE-Encoded Type III Secretion System in EPEC and EHEC: Assembly, Function, and Regulation

J. Kaper, T. Blank, J. A. Crawford, 2002 .

Characterization of Cah, a calcium‐binding and heat‐extractable autotransporter protein of enterohaemorrhagic Escherichia coli

F. Blattner, N. Perna, V. Burland, 2002, Molecular microbiology.

The Per regulon of enteropathogenic Escherichia coli : identification of a regulatory cascade and a novel transcriptional activator, the locus of enterocyte effacement (LEE)‐encoded regulator (Ler)

V. Sperandio, J. Kaper, J. Mellies, 1999, Molecular microbiology.

Part III Overview

J. Kaper, 2006 .

Quorum-Sensing Escherichia coli Regulator A: a Regulator of the LysR Family Involved in the Regulation of the Locus of Enterocyte Effacement Pathogenicity Island in Enterohemorrhagic E. coli

Vanessa Sperandio, V. Sperandio, J. Kaper, 2002, Infection and Immunity.

Comparative Sequence Analysis of the Plasmid-Encoded Regulator of Enteropathogenic Escherichia coliStrains

I. Okeke, J. Kaper, J. Mellies, 2001, Infection and Immunity.

O 157 : H 7 Escherichia coli Mechanism in Enterohemorrhagic Quorum Sensing Is a Global Regulatory

V. Sperandio, A. Torres, J. Kaper, 2001 .

The Locus of Enterocyte Effacement (LEE)-Encoded Regulator Controls Expression of Both LEE- and Non-LEE-Encoded Virulence Factors in Enteropathogenic and EnterohemorrhagicEscherichia coli

V. Sperandio, T. McDaniel, J. Kaper, 2000, Infection and Immunity.

Construction of a new vector for the expression of foreign genes inZymomonas mobilis

L. Ingram, M. Byun, J. Kaper, 1986, Journal of Industrial Microbiology.

Temporal Expression of Enteropathogenic Escherichia coli Virulence Genes in an In Vitro Model of Infection

J. Kaper, Laura Q. Leverton, 2005, Infection and Immunity.

Recombinant DNA risk assessment studies in man: efficacy of poorly mobilizable plasmids in biologic containment.

M. Levine, R. Black, J. Kaper, 1983, Recombinant DNA technical bulletin.

Escherichia coli 0157:H7 and other shiga toxin-producing E. coli strains

J. Kaper, James B. Kaper, Alison D. O'Brien, 1998 .

The Escherichia coli ycbQRST operon encodes fimbriae with laminin-binding and epithelial cell adherence properties in Shiga-toxigenic E. coli O157:H7.

J. Kaper, P. Tarr, J. Xicohtencatl-Cortes, 2009, Environmental microbiology.

MediumforthePresumptive Identification ofAeromonas hydrophila andEnterobacteriaceae

R. Colwell, J. Kaper, R. Seidler, 1979 .

Evaluation of the Accuracy and Precision of Enumerating Aerobic Heterotrophs in Water Samples by the Spread Plate Method

R. Colwell, A. Mills, J. Kaper, 1978, Applied and environmental microbiology.

The LysR-Type Transcriptional Regulator QseD Alters Type Three Secretion in Enterohemorrhagic Escherichia coli and Motility in K-12 Escherichia coli

Vanessa Sperandio, V. Sperandio, J. Kaper, 2010, Journal of bacteriology.

Effects of Vibrio cholerae recombinant strains on rabbit ileum in vivo. Enterotoxin production and myoelectric activity.

R. H. Davis, R. Guerrant, J. Kaper, 1991, Gastroenterology.

Nucleotide Sequence Analysis of the Enteropathogenic Escherichia coli Adherence Factor Plasmid pMAR7

Frederick R. Blattner, Valerie Burland, F. Blattner, 2006, Infection and Immunity.

Pathogenicity islands of intestinal E. coli.

A. Torres, J. Kaper, Alfredo G. Torres, 2002, Current topics in microbiology and immunology.

espC Pathogenicity Island of Enteropathogenic Escherichia coli Encodes an Enterotoxin

I. Okeke, J. Nataro, J. Kaper, 2001, Infection and Immunity.

Tandem tyrosine residues in the EPEC multicargo chaperone CesT support differential type III effector translocation and early host colonization

A. Abe, A. Stadnyk, J. Kaper, 2018, bioRxiv.

The Escherichia coli Common Pilus and the Bundle-Forming Pilus Act in Concert during the Formation of Localized Adherence by Enteropathogenic E. coli

I. Okeke, J. Kaper, J. Puente, 2009, Journal of bacteriology.

Persistence of cholera in the United States: isolation of Vibrio cholerae O1 from a patient with diarrhea in Maryland

T. Gross, J. Morris, J. Kaper, 1986, Journal of clinical microbiology.

Persistence of cholera in the United States.

J. Wells, J. Taylor, P. Blake, 1983, The American journal of tropical medicine and hygiene.

Evidence for a Hybrid Genomic Island in Verocytotoxin-Producing Escherichia coli CL3 (Serotype O113:H21) Containing Segments of EDL933 (Serotype O157:H7) O Islands 122 and 48

J. Kaper, M. Mascarenhas, K. Rahn, 2004, Infection and Immunity.

Construction of genetically marked Vibrio cholerae O1 vaccine strains

M. Levine, J. Kaper, J. Michalski, 1993 .

Determinants of immunogenicity and mechanisms of protection by virulent and mutant Vibrio cholerae O1 in rabbits

W. Cray, J. Mekalanos, J. Kaper, 1988, Infection and immunity.

Virulence factors in Shiga-like toxin-producing Escherichia coli isolated from humans and cattle.

T. Barrett, J. Kaper, I. Wachsmuth, 1992, The Journal of infectious diseases.

Human Epithelial Stem Cell-Derived Colonoid Monolayers as a Model to Study Shiga Toxin-Producing Escherichia coli-Host Interactions.

O. Kovbasnjuk, Julie G. In, J. Kaper, 2021, Methods in molecular biology.

MATERIALS AND METHODS Bacterial strains , media , and plasmids . V . cholerae CVD 101 and JBK 70 were derived from the 01 serotype Classical Ogawa 395 and

E. Vimr, J. Kaper, J. Galen, 2022 .

Identification and Characterization of the Locus for Diffuse Adherence, Which Encodes a Novel Afimbrial Adhesin Found in Atypical Enteropathogenic Escherichia coli

A. Torres, J. Kaper, J. Michalski, 2005, Infection and Immunity.

Progress towards a vaccine against enterotoxigenic Escherichia coli.

M. Levine, J. Kaper, Myron M. Levine, 1988, Vaccine.

Molecular and ultrastructural characterisation of EspA from different enteropathogenic Escherichia coli serotypes.

V. Sperandio, G. Dougan, J. Kaper, 1998, FEMS microbiology letters.

The ribosome binding site of a mini‐ORF protects a T3SS mRNA from degradation by RNase E

J. Belasco, J. Kaper, P. Lodato, 2012, Molecular microbiology.

Distribution of Zonula occludens toxin (zot) gene among clinical isolates of Vibrio cholerae O1 from Bangladesh and Africa.

S. Faruque, J. Kaper, M. Albert, 1994, Journal of diarrhoeal diseases research.

Quorum Sensing in the Gastrointestinal Tract

J. Kaper, J. Michalski, Christopher Prichett, 2005 .

Post‐transcriptional processing of the LEE4 operon in enterohaemorrhagic Escherichia coli

J. Kaper, P. Lodato, 2012 .

Post‐transcriptional processing of the LEE4 operon in enterohaemorrhagic Escherichia coli

J. Kaper, P. Lodato, James B. Kaper, 2009, Molecular microbiology.

Diarrheagenic Escherichia coli

J. Nataro, J. Kaper, 1998, Clinical Microbiology Reviews.

The per regulator of enteropathogenic Escherichia coli

J. Kaper, O. Gómez-Duarte, 1997, Molecular microbiology.

Safety and immunogenicity of different immunization regimens of CVD 103-HgR live oral cholera vaccine in soldiers and civilians in Thailand.

M. Levine, C. Hoge, Y. Lim, 1992, The Journal of infectious diseases.

Vibrio cholerae CVD103-HgR live oral attenuated vaccine: construction, safety, immunogenicity, excretion and non-target effects.

M. Levine, C. Tacket, J. Nataro, 1995, Developments in biological standardization.

Diarrheagenic Escherichia coli

J. Nataro, J. Kaper, 1998, Clinical Microbiology Reviews.

The ex vivo response of human intestinal mucosa to enteropathogenic Escherichia coli infection

J. Kaper, S. Schüller, A. Phillips, 2009, Cellular Microbiology.

Diarrheagenic Escherichia coli

J. Nataro, J. Kaper, 1998, Clinical Microbiology Reviews.

Descriptive epidemiology ofpersistent diarrhoea amongyoungchildren inrural northern India

M. Levine, J. Kaper, S. Sazawal, 1989 .

Molecular epidemiology of non-O1 Vibrio cholerae and Vibrio mimicus in the U.S. Gulf Coast region

J. Nataro, J. Kaper, H. Bradford, 1986, Journal of clinical microbiology.

[Tolerance and immunogenicity of an oral dose of CVD 103-HgR, a live attenuated Vibrio cholerae 01 strain: a double-blind study of Chilean adults].

G. Losonsky, J. Kaper, S. Cryz, 1993, Revista medica de Chile.

Age-specific frequencies of antibodies to Escherichia coli verocytotoxins (Shiga toxins) 1 and 2 among urban and rural populations in southern Ontario.

P. Michel, Jeff B. Wilson, J. Kaper, 2003, The Journal of infectious diseases.

environment. from an estuarine isolation of Salmonella spp. nonselective enrichment for Ambient-temperature primary

G. Sayler, R. Colwell, J. Kaper, 2013 .

Functional and Phylogenetic Analysis of ureD in Shiga Toxin-Producing Escherichia coli

D. Rasko, J. Kaper, Susan R. Steyert, 2010, Journal of bacteriology.

Pathogenic Escherichia coli.

J. Kaper, 2005, International journal of medical microbiology : IJMM.

Insertion site of the locus of enterocyte effacement in enteropathogenic and enterohemorrhagic Escherichia coli differs in relation to the clonal phylogeny of the strains.

T. Whittam, J. Kaper, Lothar H. Wieler, 1997, FEMS microbiology letters.

In vivo bioluminescence imaging of Escherichia coli O104:H4 and role of aerobactin during colonization of a mouse model of infection

A. Torres, J. Kaper, V. Popov, 2012, BMC Microbiology.

Evaluation of the Accuracy and Precision of Enumerating Aerobic Heterotrophs in Water Samples by the Spread Plate Method

R. Colwell, A. Mills, J. Kaper, 1978, Applied and environmental microbiology.