M. Leal

发表

Sensitive Deep-Sequencing-Based HIV-1 Genotyping Assay To Simultaneously Determine Susceptibility to Protease, Reverse Transcriptase, Integrase, and Maturation Inhibitors, as Well as HIV-1 Coreceptor Tropism

David L. Robertson, Miguel E. Quiñones-Mateu, D. Robertson, 2014, Antimicrobial Agents and Chemotherapy.

Improved CD4 T cell profile in HIV-infected subjects on maraviroc-containing therapy is associated with better responsiveness to HBV vaccination

E. Ruiz-Mateos, M. Leal, I. Herrero-Fernández, 2018, Journal of Translational Medicine.

Improved CD4 T-cell profile and inflammatory levels in HIV-infected subjects on maraviroc-containing therapy is associated with better responsiveness to HBV vaccination

E. Ruiz-Mateos, M. Leal, I. Rosado-Sánchez, 2018, bioRxiv.

Proteomic Profile Associated With Loss of Spontaneous Human Immunodeficiency Virus Type 1 Elite Control

Felipe García, J. Benito, A. León, 2018, The Journal of infectious diseases.

Virological Response after Short-Term CCR5 Antagonist Exposure in HIV-Infected Patients: Frequency of Subjects with Virological Response and Associated Factors

E. Ruiz-Mateos, M. Leal, Á. Muñoz-Fernández, 2011, Antimicrobial Agents and Chemotherapy.

Clinical Utility of Maraviroc

M. Leal, J. Moltó, F. Pulido, 2011, Clinical drug investigation.

A sensitive phenotypic assay for the determination of human immunodeficiency virus type 1 tropism.

S. Spijkers, E. Ruiz-Mateos, M. Leal, 2010, The Journal of antimicrobial chemotherapy.

TROCAI (Tropism Coreceptor Assay Information): a New Phenotypic Tropism Test and Its Correlation with Trofile Enhanced Sensitivity and Genotypic Approaches

E. Ruiz-Mateos, M. Leal, M. Genebat, 2010, Journal of Clinical Microbiology.

Thymic function failure and C-reactive protein levels are independent predictors of all-cause mortality in healthy elderly humans

E. Ruiz-Mateos, M. Leal, R. Solana, 2013, AGE.

Validation of the HIV Tropism Test TROCAI Using the Virological Response to a Short-Term Maraviroc Monotherapy Exposure

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2016, Antimicrobial Agents and Chemotherapy.

Correlation of the Virological Response to Short-Term Maraviroc Monotherapy with Standard and Deep-Sequencing-Based Genotypic Tropism Prediction Methods

P. Harrigan, A. Poon, E. Ruiz-Mateos, 2011, Antimicrobial Agents and Chemotherapy.

Emergence and clinical relevance of mutations associated with zidovudine resistance in asymptomatic HIV-1 infected patients

B. Larder, M. Leal, E. Lissen, 1995, European Journal of Clinical Microbiology and Infectious Diseases.

Provirus load changes in untreated and zidovudine-treated human immunodeficiency virus type 1-infected patients.

B. Larder, M. Leal, J. Pineda, 1994, The Journal of infectious diseases.

Evolution of Genotypic Resistance to Nucleoside Analogues in Patients Receiving Protease Inhibitor-Containing Regimens

B. Clotet, L. Ruiz, M. Leal, 1998, Antiviral therapy.

Dendrimers as topical microbicides with activity against HIV

M. Leal, F. J. de la Mata, R. Gómez, 2012 .

Prevalence of genotypic resistance to nucleoside analogues and protease inhibitors in Spain

B. Clotet, L. Ruiz, L. Stuyver, 2000, AIDS.

Etravirine resistance associated mutations in HIV-infected patients failing efavirenz or nevirapine in the Spanish antiretroviral resistance database

E. Poveda, V. Soriano, J. Blanco, 2010, AIDS.

Tuberculosis Therapy Modifies the Cytokine Profile, Maturation State, and Expression of Inhibitory Molecules on Mycobacterium tuberculosis-Specific CD4+ T-Cells

D. Havlir, R. Koup, M. Leal, 2016, PloS one.

Low levels of HIV-1 plasma viral load in patients infected with HIV-1 subtype b and advanced immunosuppression.

M. Leal, J. Macías, J. Pineda, 2001, The Journal of infection.

HIV‐1 viraemia changes in patients with and without syncytium‐inducing phenotype treated with nucleoside analogues: a case‐control study

M. Leal, E. Lissen, F. Medrano, 1996, European journal of clinical investigation.

Influence of human immunodeficiency virus type 1 infection on the natural course of chronic parenterally acquired Hepatitis C

M. Leal, E. Lissen, J. Aznar, 1995, European Journal of Clinical Microbiology and Infectious Diseases.

Control of HIV-1 RNA load after HAART interruption: relationship with CCR5 co-receptor density and proviral DNA load in HIV-infected patients.

M. Leal, G. Fernández, M. Muñoz-Fernández, 2007, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Immunological features beyond CD4/CD8 ratio values in older individuals

M. Leal, I. Herrero-Fernández, I. Rosado-Sánchez, 2021, Aging.

Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers

A. Mocroft, A. d’Arminio Monforte, C. Sabin, 2017, PloS one.

A Lower Baseline CD4/CD8 T-Cell Ratio Is Independently Associated with Immunodiscordant Response to Antiretroviral Therapy in HIV-Infected Subjects

E. Ruiz-Mateos, M. Leal, I. Herrero-Fernández, 2017, Antimicrobial Agents and Chemotherapy.

Glutaminolysis and lipoproteins are key factors in late immune recovery in successfully treated HIV-infected patients.

J. Blanco, E. Rodríguez-Gallego, M. Leal, 2019, Clinical science.

Analysis of quasispecies in the viral 5′ untranslated region of hepatitis C virus to evaluate ribavirin mutagenic effect in patients receiving ribavirin and interferon-alfa

M. Leal, S. Molina-Pinelo, E. Lissen, 2004, European Journal of Clinical Microbiology and Infectious Diseases.

Maintenance of virologic efficacy and decrease in levels of β2-microglobulin, soluble CD40L and soluble CD14 after switching previously treated HIV-infected patients to an NRTI-sparing dual therapy.

M. R. Benhnia, E. Ruiz-Mateos, M. Leal, 2014, Antiviral research.

The Great Recession and Immune Function

S. Galea, A. Aiello, M. Leal, 2018, RSF.

Immunity in HIV-1-Infected Adults with a Previous State of Moderate-Severe Immune-Suppression and More Than 500 CD4+ T Cell After Highly Active Antiretroviral Therapy

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernandez, 2004, Journal of Clinical Immunology.

Thymic involvement in recovery of immunity among HIV-infected adults on highly active antiretroviral therapy.

M. Leal, R. de la Rosa, 2003, The Journal of antimicrobial chemotherapy.

Zinc alpha‐2 glycoprotein is implicated in dyslipidaemia in HIV‐1‐infected patients treated with antiretroviral drugs

C. Richart, R. Pastor, J. Vendrell, 2012, HIV medicine.

Role of toll-like receptor 4 Asp299Gly polymorphism in the development of cardiovascular diseases in HIV-infected patients

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2018, AIDS.

IFNγ⁻TNFα⁻IL2⁻MIP1α⁻CD107a⁺PRF1⁺ CD8 pp65-Specific T-Cell Response Is Independently Associated With Time to Death in Elderly Humans.

R. Koup, J. Casazza, E. Ruiz-Mateos, 2015, The journals of gerontology. Series A, Biological sciences and medical sciences.

The influence of the preoperative immune response on blood transfusion requirements in patients undergoing cardiac surgery.

A. Ordóñez, M. Leal, S. Leal-Noval, 2009, Journal of cardiothoracic and vascular anesthesia.

Minimal liver injury in chronic hepatitis C virus infection is associated with low levels of soluble TNF-alpha/Fas receptors and acquisition in childhood.

M. Leal, J. Macías, J. Pineda, 2001, Liver.

Influence of hepatitis C virus infection on the mortality of antiretroviral-treated patients with HIV disease

M. Leal, J. Macías, J. Pineda, 1998, European Journal of Clinical Microbiology and Infectious Diseases.

HIV-1 Plasma Viremia not Increased in Patients Receiving Highly Active Antiretroviral Therapy After Influenza Vaccination

M. Leal, J. Macías, J. Pineda, 2001, European Journal of Clinical Microbiology and Infectious Diseases.

High frequency of serious side effects from meglumine antimoniate given without an upper limit dose for the treatment of visceral leishmaniasis in human immunodeficiency virus type-1-infected patients.

M. Leal, J. Macías, J. Pineda, 1999, The American journal of tropical medicine and hygiene.

Reduction of Immune System Activation in HIV-1-Infected Patients Undergoing Highly Active Antiretroviral Therapy

M. Leal, J. Macías, J. Pineda, 1999, European Journal of Clinical Microbiology and Infectious Diseases.

Prevalence of and Factors Associated with Visceral Leishmaniasis in Human Immunodeficiency Virus Type 1-Infected Patients in Southern Spain

M. Leal, J. A. Gallardo, J. Macías, 1998, Journal of Clinical Microbiology.

Current situation of the pharmacogenetics of immune recovery in treated HIV-infected patients.

M. Leal, F. Vidal, J. Alcamí, 2014, Pharmacogenomics.

Persistent HIV‐controllers are more prone to spontaneously clear HCV: a retrospective cohort study

Felipe García, J. Benito, A. León, 2020, Journal of the International AIDS Society.

Differential Gag-Specific Polyfunctional T Cell Maturation Patterns in HIV-1 Elite Controllers

R. Koup, J. Casazza, E. Ruiz-Mateos, 2012, Journal of Virology.

Involvement of the LPS-LPB-CD14-MD2-TLR4 inflammation pathway in HIV-1/HAART-associated lipodystrophy syndrome (HALS).

M. Arnedo, E. Martinez, X. Escoté, 2014, The Journal of antimicrobial chemotherapy.

Increased risk of non-AIDS-related events in HIV subjects with persistent low CD4 counts despite cART in the CoRIS cohort.

M. Leal, Y. Pacheco, J. Berenguer, 2015, Antiviral research.

Structural Requirements for Multimerization of the Pathogen Receptor Dendritic Cell-specific ICAM3-grabbing Non-integrin (CD209) on the Cell Surface*

Á. Corbí, M. Leal, Elena Sierra-Filardi, 2008, Journal of Biological Chemistry.

Leptin and adiponectin, but not IL18, are related with insulin resistance in treated HIV-1-infected patients with lipodystrophy.

C. Richart, J. Vendrell, X. Escoté, 2012, Cytokine.

High rate of nonspecific anti‐hepatitis C reactivity amongst homosexual men in comparison with that found in other sexually active groups and blood donors

M. Leal, J. Pineda, E. Lissen, 1994, Journal of internal medicine.

A baseline metabolomic signature is associated with immunological CD4+ T-cell recovery after 36 months of antiretroviral therapy in HIV-infected patients

X. Correig, J. Blanco, E. Rodríguez-Gallego, 2017, AIDS.

Dendrimers in RNAi Delivery

M. Leal, P. Ortega, R. Gómez, 2013 .

Specific Patterns of T Cell Immunosenescence in Vertically HIV-Infected Subjects

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2019, Handbook of Immunosenescence.

Low thymic output, peripheral homeostasis deregulation, and hastened regulatory T cells differentiation in children with 22q11.2 deletion syndrome.

M. Leal, M. Muñoz-Fernández, S. Ferrando-Martínez, 2014, The Journal of pediatrics.

HIV Infection Deregulates the Balance Between Regulatory T Cells and IL-2–Producing CD4 T Cells by Decreasing the Expression of the IL-2 Receptor in Treg

M. Leal, M. Muñoz-Fernández, Y. Pacheco, 2014, Journal of acquired immune deficiency syndromes.

Preterm neonates show marked leukopenia and lymphopenia that are associated with increased regulatory T-cell values and diminished IL-7

M. Leal, M. Muñoz-Fernandez, S. Ferrando-Martínez, 2012, Pediatric Research.

Severe immune dysregulation affects CD4⁺CD25(hi)FoxP3⁺ regulatory T cells in HIV-infected patients with low-level CD4 T-cell repopulation despite suppressive highly active antiretroviral therapy.

M. Leal, M. Genebat, M. M. Pozo-Balado, 2012, The Journal of infectious diseases.

Increased Frequencies of Myeloid-Derived Suppressor Cells Precede Immunodiscordance in HIV-Infected Subjects

M. Leal, M. Muñoz-Fernández, I. Rosado-Sánchez, 2020, Frontiers in Immunology.

A. Ordóñez, E. Ruiz-Mateos, M. Leal, 2011, AGE.

Premature immunosenescence in HIV-infected patients on highly active antiretroviral therapy with low-level CD4 T cell repopulation.

M. Leal, M. Muñoz-Fernández, S. Molina-Pinelo, 2009, The Journal of antimicrobial chemotherapy.

Relationship between CCR5(WT/Δ32) heterozygosity and HIV-1 reservoir size in adolescents and young adults with perinatally acquired HIV-1 infection.

J. Martinez-Picado, M. Martínez-Bonet, E. Ruiz-Mateos, 2017, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Maraviroc reduces the regulatory T-cell frequency in antiretroviral-naive HIV-infected subjects.

M. Martínez-Bonet, E. Ruiz-Mateos, M. Leal, 2014, The Journal of infectious diseases.

Association between a Suppressive Combined Antiretroviral Therapy Containing Maraviroc and the Hepatitis B Virus Vaccine Response

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2017, Antimicrobial Agents and Chemotherapy.

HLA-B*57 and IFNL4-Related Polymorphisms Are Associated With Protection Against HIV-1 Disease Progression in Controllers

B. Walker, C. Tural, Xu G. Yu, 2016, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

IL28B single-nucleotide polymorphism rs12979860 is associated with spontaneous HIV control in white subjects.

E. Ruiz-Mateos, M. Leal, M. Genebat, 2013, The Journal of infectious diseases.

Plasmacytoid Dendritic Cells Reduce HIV Production in Elite Controllers

E. Ruiz-Mateos, M. Leal, J. Herbeuval, 2012, Journal of Virology.

Prevalence of HIV-1 Dual Infection in Long-Term Nonprogressor–Elite Controllers

E. Ruiz-Mateos, M. Leal, J. del Romero, 2013, Journal of acquired immune deficiency syndromes.

Hepatitis B virus occult infection in subjects with persistent isolated anti-HBc reactivity.

J. Prieto, M. Leal, J. Pineda, 1993, Journal of hepatology.

Toll-Like Receptor 7 (TLR-7) and TLR-9 Agonists Improve Hepatitis C Virus Replication and Infectivity Inhibition by Plasmacytoid Dendritic Cells

E. Domingo, E. Ruiz-Mateos, M. Leal, 2018, Journal of Virology.

Association between IL28B gene polymorphisms and plasma HCV-RNA levels in HIV/HCV-co-infected patients

J. Miro, E. Poveda, V. Soriano, 2011, AIDS.

Influence of the Toll-Like Receptor 9 1635A/G Polymorphism on the CD4 Count, HIV Viral Load, and Clinical Progression

R. Ramírez-Lorca, M. Leal, A. Vallejo, 2008, Journal of acquired immune deficiency syndromes.

Anionic Carbosilane Dendrimers Destabilize the GP120-CD4 Complex Blocking HIV-1 Entry and Cell to Cell Fusion.

F. González-Nilo, M. J. Serramía, M. Leal, 2018, Bioconjugate chemistry.

CCR5+ CD8 T-cell levels and monocyte activation precede the onset of acute coronary syndrome in HIV-infected patients on antiretroviral therapy

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2017, Thrombosis and Haemostasis.

Altered Expression of CD300a Inhibitory Receptor on CD4+ T Cells From Human Immunodeficiency Virus-1-Infected Patients: Association With Disease Progression Markers

E. Ruiz-Mateos, M. Leal, F. Borrego, 2018, Front. Immunol..

Consensus conference on chronic viral hepatitis and HIV infection: updated Spanish recommendations

C. Tural, J. Miro, V. Soriano, 2004, Journal of viral hepatitis.

signaling, and its expression is down-regulated in HIV infection CD300a is expressed on human B cells, modulates BCR-mediated

J. Coligan, M. Leal, S. Moir, 2014 .

CD300a is expressed on human B cells, modulates BCR-mediated signaling, and its expression is down-regulated in HIV infection.

J. Coligan, M. Leal, F. Borrego, 2011, Blood.

CD27 and CCR7 expression on naive T cells, are both necessary?

E. Ruiz-Mateos, M. Leal, S. Ferrando-Martínez, 2010, Immunology letters.

Phenotype and Polyfunctional Deregulation Involving Interleukin 6 (IL-6)- and IL-10-Producing Monocytes in HIV-Infected Patients Receiving Combination Antiretroviral Therapy Differ From Those in Healthy Older Individuals.

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2016, The Journal of infectious diseases.

Primary HIV‐1 drug resistance in Spain before and after the introduction of protease inhibitors

B. Clotet, L. Ruiz, V. Soriano, 2001, Journal of medical virology.

Presence of Genotypic Resistance in Nucleoside Analogue-Treated HIV-1-Infected Patients with Undetectable Viral Load

B. Clotet, L. Ruiz, L. Zamora, 1999, Antiviral therapy.

Efficiency of Drug Resistance Genotypic Tests in Specimens with Low HIV Viral Load

Soriano, B. Clotet, L. Ruiz, 1998, Antiviral therapy.

Long-term suppressive combined antiretroviral treatment does not normalize the serum level of soluble CD14.

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2013, The Journal of infectious diseases.

A reliable and simplified sj/beta-TREC ratio quantification method for human thymic output measurement.

E. Ruiz-Mateos, M. Leal, S. Ferrando-Martínez, 2010, Journal of immunological methods.

Thymopoiesis in elderly human is associated with systemic inflammatory status

M. Leal, S. Ferrando-Martínez, E. Gutiérrez, 2009, AGE.

Thymic Function-Related Markers Within the Thymus and Peripheral Blood: Are They Comparable?

E. Ruiz-Mateos, M. Leal, S. Molina-Pinelo, 2006, Journal of Clinical Immunology.

Effect of Maraviroc on HIV Disease Progression-Related Biomarkers

E. Ruiz-Mateos, M. Leal, M. Genebat, 2012, Antimicrobial Agents and Chemotherapy.

Maraviroc contributes to the restoration of the homeostasis of regulatory T-cell subsets in antiretroviral-naive HIV-infected subjects.

M. R. Benhnia, E. Ruiz-Mateos, M. Leal, 2016, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Correlation between the Trofile test and virological response to a short-term maraviroc exposure in HIV-infected patients.

E. Ruiz-Mateos, M. Leal, M. Genebat, 2009, The Journal of antimicrobial chemotherapy.

Genotypic resistance profile in treatment-experienced HIV-infected individuals after abacavir and efavirenz salvage regimen.

M. Leal, E. Lissen, A. Vallejo, 2004, Antiviral research.

Predictive value of the presence of P24 antigen in persons with antibodies to human immunodeficiency virus in Spain

M. Leal, J. Pineda, E. Lissen, 1989, European Journal of Clinical Microbiology and Infectious Diseases.

HIV infection-related premature immunosenescence: high rates of immune exhaustion after short time of infection.

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2011, Current HIV research.

Combination of G2-S16 dendrimer/dapivirine antiretroviral as a new HIV-1 microbicide.

M. Leal, M. Muñoz-Fernández, J. L. Jiménez, 2019, Future medicinal chemistry.

Synergistic activity of carbosilane dendrimers in combination with maraviroc against HIV in vitro

M. Leal, R. Gómez, M. Muñoz-Fernández, 2013, AIDS.

Differential alterations of the CD4 and CD8 T cell subsets in HIV-infected patients on highly active antiretroviral therapy with low CD4 T cell restoration.

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2012, The Journal of antimicrobial chemotherapy.

Endogenous IL-7 is associated with increased thymic volume in adult HIV-infected patients under highly active antiretroviral therapy

E. Ruiz-Mateos, M. Leal, E. Lissen, 2003, AIDS.

HIV-Infected Subjects With Poor CD4 T-Cell Recovery Despite Effective Therapy Express High Levels of OX40 and α4β7 on CD4 T-Cells Prior Therapy Initiation

D. Podzamczer, J. Olalla, M. Leal, 2018, Front. Immunol..

Hepatitis C virus infection in sexually promiscuous groups

M. Leal, J. Pineda, E. Lissen, 1990, European Journal of Clinical Microbiology and Infectious Diseases.

Adipokines as New Biomarkers of Immune Recovery: Apelin Receptor, RBP4 and ZAG Are Related to CD4+ T-Cell Reconstitution in PLHIV on Suppressive Antiretroviral Therapy

E. Negredo, J. Mallolas, J. Blanco, 2022, International journal of molecular sciences.

Increased regulatory T cell counts in HIV-infected nonresponders to hepatitis B virus vaccine.

M. Leal, Y. Pacheco, P. Viciana, 2010, The Journal of infectious diseases.

CD4(+)CD25(+/hi)CD127(lo) phenotype does not accurately identify regulatory T cells in all populations of HIV-infected persons.

M. Leal, Y. Pacheco, G. Méndez-Lagares, 2010, The Journal of infectious diseases.

M. Arnedo, E. Martinez, J. Vendrell, 2015, PloS one.

T-cell repopulation and thymic volume in HIV-1-infected adult patients after highly active antiretroviral therapy.

M. Leal, E. Lissen, A. Sánchez-Quijano, 2002, Blood.

Baseline Thymic Volume is a Predictor for CD4 T Cell Repopulation in Adult HIV-Infected Patients under Highly Active Antiretroviral Therapy

E. Ruiz-Mateos, M. Leal, E. Lissen, 2001, Antiviral therapy.

Patients on a combined antiretroviral therapy after maraviroc clinical test show no immunovirological impairment.

E. Ruiz-Mateos, M. Leal, M. Genebat, 2012, Antiviral research.

Discordance rates between Trofile test and short-term virological response to maraviroc.

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2011, Antiviral research.

Tropism Coreceptor Assay Information ) : a new phenotypic 1 tropism test and its correlation with TROFILE ® ( ES ) and genotypic 2 approaches 3 4

E. Ruiz-Mateos, M. Leal, M. Genebat, 2010 .

Thymic Function Impacts the Peripheral CD4/CD8 Ratio of HIV-Infected Subjects

E. Ruiz-Mateos, M. Leal, I. Herrero-Fernández, 2017, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Disseminate and fatal cytomegalovirus disease with thymitis in a naive HIV-patient after early initiation of HAART: immune restoration disease?

E. Ruiz-Mateos, M. Leal, M. Genebat, 2006, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Thymic volume is associated independently with the magnitude of short‐ and long‐term repopulation of CD4+ T cells in HIV‐infected adults after highly active antiretroviral therapy (HAART) 1

E. Ruiz-Mateos, M. Leal, E. Lissen, 2004, Clinical and experimental immunology.

Changes in thymus volume in adult HIV‐infected patients under HAART: correlation with the T‐cell repopulation

E. Ruiz-Mateos, M. Leal, E. Lissen, 2002, Clinical and experimental immunology.

Evidence of thymic function in heavily antiretroviral-treated human immunodeficiency virus type 1-infected adults with long-term virologic treatment failure.

E. Ruiz-Mateos, M. Leal, E. Lissen, 2002, The Journal of infectious diseases.

Antibodies to human T-cell leukemia virus type III in hemophiliacs from Spain.

M. Ollero, M. Leal, E. Lissen, 1985, Blood.

Factors associated with collagen deposition in lymphoid tissue in long-term treated HIV-infected patients

Antonio Martínez, Felipe García, M. Plana, 2010, AIDS.

Threshold Ferritin Concentrations Reflecting Early Iron Deficiency Based on Hepcidin and Soluble Transferrin Receptor Serum Levels in Patients with Absolute Iron Deficiency

M. Leal, M. Genebat, L. Tarancón-Díez, 2022, Nutrients.

The role of serology in the diagnosis and prognosis of visceral leishmaniasis in patients coinfected with human immunodeficiency virus type-1.

M. Leal, J. Alvar, E. Lissen, 1998, The American journal of tropical medicine and hygiene.

Is hepatitis G virus transmitted sexually?

M. Leal, J. Pineda, E. Lissen, 1997, JAMA.

Influence of red blood cell transfusion on CD4+ T-helper cells immune response in patients undergoing cardiac surgery.

M. Leal, S. Leal-Noval, M. Múñoz-Gómez, 2010, The Journal of surgical research.

Natural Pregnancies in HIV-Serodiscordant Couples Receiving Successful Antiretroviral Therapy

V. Soriano, M. Leal, J. del Romero, 2006, Journal of acquired immune deficiency syndromes.

Human immunodeficiency virus infection modifies the natural history of chronic parenterally-acquired hepatitis C with an unusually rapid progression to cirrhosis.

M. Leal, L. Rodrigo, M. García-Bengoechea, 1997, Journal of hepatology.

Visceral leishmaniasis in HIV‐1 -infected individuals: a common opportunistic infection in Spain?

M. Leal, I. Velez, J. Pineda, 1992, AIDS.

Antibodies to the AIDS-associated retrovirus in hemophiliacs and other individuals from southern Spain: lack of correlation with lymphocytes sub-populations.

J. Levy, M. Ollero, M. Leal, 1984, AIDS research.

Pre-transplant thymic function is associated with the risk of cytomegalovirus disease after solid organ transplantation.

M. Leal, R. Solana, J. Torre-Cisneros, 2015, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Effect of Hepatitis C Virus Coinfection on Humoral Immune Alterations in Naïve HIV-Infected Adults on HAART: A Three Year Follow-Up Study

E. Ruiz-Mateos, M. Leal, S. Molina-Pinelo, 2005, Journal of Clinical Immunology.

Intrinsic TGF-β signaling promotes age-dependent CD8+ T cell polyfunctionality attrition.

R. Koup, R. Bhadra, I. Khan, 2014, The Journal of clinical investigation.

Hepatitis E virus and HIV infection in homosexual men

M. Leal, E. Lissen, F. Medrano, 1995, The Lancet.

[Spanish cohort of naïve HIV-infected patients (CoRIS): rationale, organization and initial results].

Santiago Pérez-Hoyos, Santiago Moreno, Félix Gutiérrez, 2007, Enfermedades infecciosas y microbiologia clinica.

Impact of drug resistance genotypes on CD4+ counts and plasma viremia in heavily antiretroviral‐experienced HIV‐infected patients

J. Martinez-Picado, B. Rodés, V. Soriano, 2005, Journal of medical virology.

Specific patterns of CD4-associated immunosenescence in vertically HIV-infected subjects.

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2013, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Title: Improved CD4 T-cell profile and inflammatory levels in HIV-infected subjects

E. Ruiz-Mateos, M. Leal, I. Rosado-Sánchez, 2018 .

Rotative agitation RIA. A high sensitivity technique for hepatitis B surface antigen (HBsAg) determinations.

M. Leal, J. Pineda, E. Lissen, 1986, Journal of hepatology.

HCV RNA in peripheral blood cell subsets in HCV–HIV coinfected patients at the end of PegIFN/RBV treatment is associated with virologic relapse

M. Leal, S. Molina-Pinelo, L. López-Cortés, 2009, Journal of viral hepatitis.

Different profiles of immune reconstitution in children and adults with HIV-infection after highly active antiretroviral therapy

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2006, BMC infectious diseases.

Potent and Sustained Antiviral Response of Raltegravir-based Highly Active Antiretroviral Therapy in HIV Type 1-infected Children and Adolescents

M. Leal, M. Muñoz-Fernandez, V. Briz, 2012, The Pediatric infectious disease journal.

Stopping antiretroviral therapy in 'prematurely treated' HIV-1-infected children with full viral supression is safe.

M. Leal, Á. Muñoz-Fernández, I. Obando, 2006, AIDS.

Non-Steroidal Anti-Inflammatory Drugs Increase the Antiretroviral Activity of Nucleoside Reverse Transcriptase Inhibitors in HIV Type-1-Infected T-Lymphocytes: Role of Multidrug Resistance Protein 4

O. Turriziani, M. Fresno, S. Álvarez, 2009, Antiviral therapy.

Altered metabolism of gut microbiota contributes to chronic immune activation in HIV-infected individuals

A. Latorre, M. Leal, M. Gosalbes, 2014, Mucosal Immunology.

Different biological significance of sCD14 and LPS in HIV-infection: importance of the immunovirology stage and association with HIV-disease progression markers.

E. Ruiz-Mateos, M. Leal, Y. Pacheco, 2012, The Journal of infection.

Absence of HTLV-I and HTLV-II infection in prostitutes in the area of seville, Spain

M. Leal, J. Pineda, M. Essex, 1991, European Journal of Clinical Microbiology and Infectious Diseases.

Thymic function failure and C-reactive protein levels are independent predictors of all-cause mortality in healthy elderly humans

E. Ruiz-Mateos, M. Leal, R. Solana, 2013, AGE.

Coronavirus Disease (COVID-19): A Perspective from Immunosenescence

M. Leal, M. Genebat, L. Tarancón-Díez, 2021, Aging and disease.

Effect of homeostatic T-cell proliferation in the vaccine responsiveness against influenza in elderly people

A. Carrillo-Vico, M. Leal, I. Herrero-Fernández, 2019, Immunity & Ageing.

Thymic Function Failure Is Associated With Human Immunodeficiency Virus Disease Progression

R. Koup, E. Ruiz-Mateos, M. Leal, 2017, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Population Distributions of Thymic Function in Adults: Variation by Sociodemographic Characteristics and Health Status

D. Wildman, A. Aiello, M. Leal, 2016, Biodemography and social biology.

TNF-α levels in HIV-infected patients after long-term suppressive cART persist as high as in elderly, HIV-uninfected subjects.

A. Carrillo-Vico, E. Ruiz-Mateos, M. Leal, 2014, The Journal of antimicrobial chemotherapy.

Development of Immature CD4+CD8+T Cells Into Mature CD4+ T Cells Requires Alpha-1 Antitrypsin as Observed by Treatment in HIV-1 Infected and Uninfected Controls

R. Winston, C. Bristow, E. Ruiz-Mateos, 2019, Front. Cell Dev. Biol..

Clinical Outcome of HIV-Infected Patients with Sustained Virologic Response to Antiretroviral Therapy: Long-Term Follow-Up of a Multicenter Cohort

M. Leal, F. Vidal, J. Blanco, 2006, PloS one.

Hepatitis C virus infection among sexually promiscuous groups and the heterosexual partners of hepatitis C virus infected index cases

M. Leal, H. Alter, J. Pineda, 1993, European Journal of Clinical Microbiology and Infectious Diseases.

Can the Determination of HIV‐1 Ag in Serum Be Useful in Identifying Hemophiliac Patients who End up Developing AIDS?

M. Leal, J. Pineda, E. Lissen, 1989, Vox sanguinis.

Unexpected high prevalence of hepatitis C virus genotype 4 in Southern Spain.

M. Leal, J. Macías, J. Pineda, 1997, Journal of hepatology.

Failure to detect silent HIV infection by polymerase chain reaction in subjects at risk for heterosexually transmitted HIV type 1 infection

M. Leal, J. Pineda, E. Lissen, 1993, European Journal of Clinical Microbiology and Infectious Diseases.

HLA-B*57 and IFNL4-related polymorphisms are associated with protection against HIV-1 disease progression in controllers.

B. Walker, C. Tural, M. Lichterfeld, 2017, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Pegylated Interferon-&agr;–Induced Natural Killer Cell Activation Is Associated With Human Immunodeficiency Virus-1 DNA Decline in Antiretroviral Therapy–Treated HIV-1/Hepatitis C Virus–Coinfected Patients

Xu G. Yu, Zhengyu Ouyang, M. Lichterfeld, 2018, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Class-modeling analysis reveals T-cell homeostasis disturbances involved in loss of immune control in elite controllers

M. C. Ortiz, L. Sarabia, Felipe García, 2018, BMC Medicine.

Rate and predictors of progression in elite and viremic HIV-1 controllers

Felipe García, J. Gatell, J. Benito, 2016, AIDS.

Dysregulation of iron metabolism modulators in virologically suppressed HIV-infected patients

M. Leal, M. M. Pozo-Balado, Y. Pacheco, 2022, Frontiers in Immunology.

CD4+ and CD8+ T lymphocyte regeneration after anti‐retroviral therapy in HIV‐1‐infected children and adult patients

M. Leal, J. Macías, J. Pineda, 2000, Clinical and experimental immunology.

Risk, Diagnostic and Predictor Factors for Classical Hodgkin Lymphoma in HIV-1-Infected Individuals: Role of Plasma Exosome-Derived miR-20a and miR-21

M. Leal, Y. Pacheco, C. Quereda, 2020, Journal of clinical medicine.

Pharmacogenetics of the lipodystrophy syndrome associated with HIV infection and combination antiretroviral therapy

F. Villarroya, M. Arnedo, M. Leal, 2011, Expert opinion on drug metabolism & toxicology.

Prevalence of CCR5-tropic HIV-1 Among Treatment-Experienced Individuals in Spain

B. Clotet, M. Leal, S. Moreno, 2009, HIV clinical trials.

Rate of development of mutation at codon 215 of HIV‐1 reverse transcriptase and its predictive factors at the time of initiation of zidovudine therapy

M. Leal, E. Lissen, Y. Torres, 1996, European journal of clinical investigation.

Hepatitis C virus replication in Caucasian HIV controllers

E. Ruiz-Mateos, M. Leal, M. Genebat, 2011, Journal of viral hepatitis.

Toll-like receptor 9 1635A/G polymorphism is associated with HIV-1 rebound after four weeks of interruption of antiretroviral therapy.

M. Leal, M. González-Escribano, S. Molina-Pinelo, 2020, Journal of acquired immune deficiency syndromes.

CD8 TCR β chain repertoire expansions and deletions are related with immunologic markers in HIV-1-infected patients during treatment interruption.

M. Leal, A. Vallejo, A. Gonzalez-Serna, 2013, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

IFNL4 ss469415590 polymorphism is associated with unfavourable clinical and immunological status in HIV-infected individuals.

M. R. Benhnia, E. Ruiz-Mateos, M. Leal, 2015, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Evaluation of the pharmacogenetics of immune recovery in treated HIV-infected patients

C. Richart, M. Leal, Y. Pacheco, 2014, Expert opinion on drug metabolism & toxicology.

Longitudinal age differences in humoral responses to the COVID-19 vaccine in the elderly are lost after the third dose

M. Leal, M. M. Pozo-Balado, Y. Pacheco, 2022, Journal of Infection.

Factors Leading to the Loss of Natural Elite Control of HIV-1 Infection

J. Prado, Felipe García, M. Plana, 2017, Journal of Virology.

Synergistic activity profile of carbosilane dendrimer G2-STE16 in combination with other dendrimers and antiretrovirals as topical anti-HIV-1 microbicide.

M. Leal, R. Gómez, M. Muñoz-Fernández, 2014, Nanomedicine : nanotechnology, biology, and medicine.

Plasmacytoid dendritic cells (pDCs) from HIV controllers produce interferon-α and differentiate into functional killer pDCs under HIV activation.

E. Ruiz-Mateos, M. Leal, J. Herbeuval, 2012, The Journal of infectious diseases.

Hepatitis C therapy with interferon-α and ribavirin reduces CD4 T-cell-associated HIV-1 DNA in HIV-1/hepatitis C virus-coinfected patients.

Xu G. Yu, M. Lichterfeld, E. Ruiz-Mateos, 2014, The Journal of infectious diseases.

Recombinant EIA for Anti‐HIV Testing is More Specific than Conventional EIA

M. Leal, J. Pineda, E. Lissen, 1988, Vox sanguinis.

Immune Correlates of Natural HIV Elite Control and Simultaneous HCV Clearance—Supercontrollers

R. Koup, E. Ruiz-Mateos, M. Leal, 2018, Front. Immunol..

Significance of indeterminate reactivity to human T-Cell lymphotropic virus in Western blot analysis of individuals at risk

V. Soriano, M. Leal, E. Lissen, 1997, European Journal of Clinical Microbiology and Infectious Diseases.

International Congress of Drug Therapy in HIV Infection 2‐6 November 2014, Glasgow, UK

Samit R. Joshi, Charlene A Flash, Thomas Lengauer, 2014 .

Structural normalization of the lymphoid tissue in asymptomatic HIV-infected patients after 48 weeks of potent antiretroviral therapy

M. Leal, J. Macías, J. Pineda, 2001, AIDS.

Immunometabolism is a key factor for the persistent spontaneous elite control of HIV-1 infection

E. Rodríguez-Gallego, E. Ruiz-Mateos, M. Leal, 2019, EBioMedicine.

Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies

Michael Y. Gerner, J. Mascola, R. Germain, 2017, Science Translational Medicine.

An in vitro system of autologous lymphocytes culture that allows the study of homeostatic proliferation mechanisms in human naive CD4 T-cells

M. Leal, I. Herrero-Fernández, I. Rosado-Sánchez, 2018, Laboratory Investigation.

The TLR4 ASP299GLY polymorphism is a risk factor for active tuberculosis in Caucasian HIV-infected patients.

M. Leal, M. Genebat, Y. Pacheco, 2010, Current HIV research.

Polyfunctional HIV-1 specific response by CD8+ T lymphocytes expressing high levels of CD300a

E. Ruiz-Mateos, M. Leal, F. Borrego, 2020, Scientific Reports.

Spectrofluorimetric analysis of CCR5-delta 32 allele using real-time polymerase chain reaction: prevalence in southern Spanish HIV(+) patients and noninfected population.

S. Borrego, G. Antiñolo, M. Leal, 2001, AIDS research and human retroviruses.

Prevalence of infection by human T-cell leukemia virus types I and II in southern Spain

V. Soriano, M. Leal, J. Sánchez-Román, 1995, European Journal of Clinical Microbiology and Infectious Diseases.

Tumor Necrosis Factor β and Soluble APO-1/Fas Independently Predict Progression to AIDS in HIV-Seropositive Patients

M. Clerici, M. Leal, E. Lissen, 1998 .

Prevalence of neurosyphilis in human immunodeficiency virus-infected patients with latent syphilis.

M. Leal, R. Larsen, P. Holtom, 1992, The American journal of medicine.

The effects of prebiotics on microbial dysbiosis, butyrate production and immunity in HIV-infected subjects

M. Ferrer, M. Motilva, C. Barbas, 2016, Mucosal Immunology.

Partial restoration of gut‐mucosal dysbiosis in late‐treated HIV‐infected subjects with CD4 T‐cell recovery

M. Leal, I. Herrero-Fernández, I. Rosado-Sánchez, 2022, Clinical and translational medicine.

Higher levels of IL-6, CD4 turnover and Treg frequency are already present before cART in HIV-infected subjects with later low CD4 recovery.

J. Blanco, E. Rodríguez-Gallego, M. Leal, 2017, Antiviral research.

Drug resistance in patients experiencing early virological failure under a triple combination including indinavir

V. Soriano, M. Leal, J. Arribas, 2001, AIDS.

Hepatitis C virus and cumulative infections are associated with atherogenic cardiovascular events in HIV-infected subjects.

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2019, Antiviral research.

Higher plasma levels of thymosin-α1 are associated with a lower waning of humoral response after COVID-19 vaccination: an eight months follow-up study in a nursing home

M. Leal, M. M. Pozo-Balado, C. Lozano, 2023, Immunity & Ageing.

Epidemiology of HIV-2 infection in Spain

A. Heredia, V. Soriano, I. Hewlett, 1996, European Journal of Clinical Microbiology and Infectious Diseases.

Rate, causes, and clinical implications of presenting with low CD4+ cell counts in the era of highly active antiretroviral therapy.

V. Soriano, M. Leal, J. González-lahoz, 2003, AIDS research and human retroviruses.

Changes in the rate of genotypic resistance to antiretroviral drugs in Spain.

B Clotet, B. Clotet, L. Ruiz, 2001, AIDS.

Prevalence of genotypic resistance to nucleoside analogues in antiretroviral‐naive and antiretroviral‐experienced HIV‐infected patients in Spain

B. Clotet, L. Ruiz, V. Soriano, 1998, AIDS.

Circulating metabolomic profile can predict dyslipidemia in HIV patients undergoing antiretroviral therapy.

E. Rodríguez-Gallego, R. Beltrán-Debón, E. Ruiz-Mateos, 2018, Atherosclerosis.

Increased frequencies of Th17 cells and IL17a-producing regulatory T-cells preceding the immunodiscordant response to antiretroviral treatment.

M. Leal, I. Herrero-Fernández, I. Rosado-Sánchez, 2018, The Journal of infection.

Risk factors, CD4 long-term evolution and mortality of HIV-infected patients who persistently maintain low CD4 counts, despite virological response to HAART.

M. Leal, Y. Pacheco, F. Vidal, 2009, Current HIV research.

Prevalence and factors involved in discordant responses to highly active antiretroviral treatment in a closely followed cohort of treatment-naïve HIV-infected patients.

M. Leal, G. Fernández, M. Muñoz-Fernández, 2005, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

HIV-1 progression in hepatitis-C-infected drug users

M. Leal, J. Macías, J. Pineda, 2001, The Lancet.

Maraviroc Once-Daily Nucleoside Analog-Sparing Regimen in Treatment-Naive Patients: Randomized, Open-Label Pilot Study

D. Podzamczer, H. Valdez, M. Leal, 2013, Journal of acquired immune deficiency syndromes.

Analysis of Non-AIDS-Defining Events in HIV Controllers.

Felipe García, J. Benito, A. León, 2016, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Sticking Up for the Immune System Integrity: Should the Thymus Be Preserved During Cardiac Surgery?

M. Leal, M. Muñoz-Fernandez, S. Ferrando-Martínez, 2012 .

Is it age or HIV that drives the regulatory T-cells expansion that occurs in older HIV-infected persons?

M. Leal, Y. Pacheco, G. Méndez-Lagares, 2010, Clinical immunology.

High prevalence of X4/DM-tropic variants in children and adolescents infected with HIV-1 by vertical transmission.

E. Ruiz-Mateos, M. Leal, M. de Mulder, 2012, The Pediatric infectious disease journal.

Immunovirologic characteristics of human immunodeficiency virus-infected patients consisting mainly of injecting drug users on highly active antiretroviral treatment with prolonged virologic failure.

E. Ruiz-Mateos, M. Leal, S. Molina-Pinelo, 2006, Viral immunology.

New signatures of poor CD4 cell recovery after suppressive antiretroviral therapy in HIV-1-infected individuals: involvement of miR-192, IL-6, sCD14 and miR-144

J. Blanco, M. Leal, I. Rosado-Sánchez, 2020, Scientific Reports.

Long‐term suppression of plasma viremia with highly active antiretroviral therapy despite virus evolution and very limited selection of drug‐resistant genotypes

E. Domingo, J. Benito, M. Leal, 2004, Journal of medical virology.

Glycoprotein Profile Assessed by 1H-NMR as a Global Inflammation Marker in Patients with HIV Infection. A Prospective Study

X. Correig, M. Leal, J. Girona, 2020, Journal of clinical medicine.

Increase in the frequency of mutation at codon 215 associated with zidovudine resistance in HIV-1-infected antiviral-naive patients from 1989 to 1996.

M. Leal, J. Pineda, E. Lissen, 1997, AIDS.

NK-associated regulatory receptors in a structured HAART interruption of HIV-1-positive individuals.

M. Leal, J. Lozano, J. Peña, 2008, AIDS research and human retroviruses.

Increased CD127+ and decreased CD57+ T cell expression levels in HIV-infected patients on NRTI-sparing regimens

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2017, Journal of Translational Medicine.

CD4+ T-lymphocytopenia in the elderly

M. Leal, E. Calderón, F. Medrano, 2005, European Journal of Clinical Microbiology and Infectious Diseases.

High levels of CD57+CD28- T-cells, low T-cell proliferation and preferential expansion of terminally differentiated CD4+ T-cells in HIV-elite controllers.

E. Ruiz-Mateos, M. Leal, M. Genebat, 2010, Current HIV research.

PREVENTION OF POST-TRANSFUSION NON-A, NON-B HEPATITIS BY NON-SPECIFIC IMMUNOGLOBULIN IN HEART SURGERY PATIENTS

M. Leal, J. Pineda, E. Lissen, 1988, The Lancet.

Regression of invasive AIDS-related Kaposi's sarcoma following antiretroviral therapy.

V. Soriano, M. Leal, J. Macías, 1998, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

HTLV‐I and HTLV‐II Infections in Spain

V. Soriano, M. Ollero, M. Leal, 1993, Vox sanguinis.

Avoiding Indeterminate Results in HIV‐1 Western Blot Using Synthetic Peptide Assays

M. Leal, V. Soriano, A. Aguilera, 1993, Vox sanguinis.

Detectable Viral Load Aggravates Immunosenescence Features of CD8 T-Cell Subsets in Vertically HIV-Infected Children

E. Ruiz-Mateos, M. Leal, M. M. Pozo-Balado, 2012, Journal of acquired immune deficiency syndromes.

Persistent Exhausted T-Cell Immunity after Severe COVID-19: 6-Month Evaluation in a Prospective Observational Study

M. Leal, M. Genebat, L. Tarancón-Díez, 2023, Journal of clinical medicine.

Patients' characteristics and clinical implications of suboptimal CD4 T-cell gains after 1 year of successful antiretroviral therapy.

M. Leal, M. Salavert, F. Vidal, 2008, Current HIV research.

Effect of homeostatic T-cell proliferation in the vaccine responsiveness against influenza in elderly people

A. Carrillo-Vico, M. Leal, I. Herrero-Fernández, 2019, Immunity & Ageing.

An easy and quick method for the diagnosis of visceral leishmaniasis in HIV‐1-infected individuals

M. Leal, F. Medrano, E. Jiménez-Mejías, 1993, AIDS.

Rate of Virological Treatment Failure and Frequencies of Drug Resistance Genotypes among Human Immunodeficiency Virus-Positive Subjects on Antiretroviral Therapy in Spain

B. Clotet, L. Ruiz, V. Soriano, 2002, Journal of Clinical Microbiology.

Incidence and risk factors for tuberculosis in HIV-positive subjects by HAART status.

M. Leal, M. Leal, F. Vidal, 2008, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Patient HIV-1 strains carrying the multiple nucleoside resistance mutations are cross-resistant to abacavir.

E. De Clercq, T. Harrer, B. Clotet, 2000, AIDS.

Effects of Different Antigenic Stimuli on Thymic Function and Interleukin-7/CD127 System in Patients with Chronic HIV Infection

Felipe García, M. Plana, T. Pumarola, 2014, Journal of acquired immune deficiency syndromes.

Prevalence and resistance mutations of non-B HIV-1 subtypes among immigrants in Southern Spain along the decade 2000-2010

M. Leal, F. Fernández-Cuenca, P. Viciana, 2011, Virology Journal.

Association of heterozygous CCR5Δ32 deletion with survival in HIV-infection: A cohort study.

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2018, Antiviral research.

High CD8 T cell percentage and HCV replication control are common features in HIV-1 controllers and HTLV-2-co-infected patients with a history of injection drug use.

E. Ruiz-Mateos, M. Leal, L. Tarancón-Díez, 2019, Virus research.

Multiple dideoxynucleoside analogue‐resistant (MddNR) HIV‐1 strains isolated from patients from different European countries

T. Harrer, B. Clotet, L. Ruiz, 1998, AIDS.

WNT signaling suppression in the senescent human thymus.

David P. Kreil, M. V. D. van den Brink, E. Ruiz-Mateos, 2015, The journals of gerontology. Series A, Biological sciences and medical sciences.

Carbosilane dendrons with fatty acids at the core as a new potential microbicide against HSV-2/HIV-1 co-infection.

M. Leal, R. Gómez, M. Muñoz-Fernández, 2017, Nanoscale.

Usefulness of Route of Transmission, Absolute CD8+ T-Cell Counts, and Levels of Serum Tumor Necrosis Factor Alpha as Predictors of Survival of HIV-1-Infected Patients with Very Low CD4+ T-Cell Counts

M. Leal, J. Macías, J. Pineda, 2001, European Journal of Clinical Microbiology and Infectious Diseases.

[Cost-benefit analysis of a program for vaccination against hepatitis B in health personnel of a hospital].

M. Leal, E. Lissen, A. Sánchez-Quijano, 1984, Medicina clinica.

HIV/antiretroviral therapy-related lipodystrophy syndrome (HALS) is associated with higher RBP4 and lower omentin in plasma.

M. Arnedo, E. Martinez, J. Vendrell, 2015, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

HIV-1 Tropism Evolution after Short-Term Maraviroc Monotherapy in HIV-1-Infected Patients

E. Ruiz-Mateos, M. Leal, M. Muñoz-Fernández, 2012, Antimicrobial Agents and Chemotherapy.

Incidence of and Risk Factors for Symptomatic Visceral Leishmaniasis among Human Immunodeficiency Virus Type 1-Infected Patients from Spain in the Era of Highly Active Antiretroviral Therapy

M. Leal, J. Macías, J. Pineda, 2002, Journal of Clinical Microbiology.

Long-term benefits of nevirapine-containing regimens: multicenter study with 506 patients, followed-up a median of 9 years.

D. Podzamczer, J. Mallolas, M. Leal, 2012, Current HIV research.

Influence of hepatitis C and hepatitis G virus co-infection on viral and cellular dynamics in patients infected with human immunodeficiency virus following interruption of highly active anti-retroviral therapy.

M. Leal, A. Vallejo, M. Abad, 2006, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Short-term maraviroc exposure, a clinical approach to decide on maraviroc prescription in HIV-1-infected treatment-naïve patients

E. Ruiz-Mateos, M. Leal, M. Genebat, 2016, Drug Design, Development and Therapy.

Maraviroc Clinical Test (MCT) as an alternative tool to decide CCR5-antagonists prescription in naïve HIV-infected patients.

E. Ruiz-Mateos, M. Leal, M. Genebat, 2015, Antiviral research.

Long-term immunovirogical effect and tolerability of a maraviroc-containing regimen in routine clinical practice.

E. Ruiz-Mateos, M. Leal, M. Genebat, 2010, Current HIV research.

Low Sensitivity of Peripheral Blood Smear for Diagnosis of Subclinical Visceral Leishmaniasis in Human Immunodeficiency Virus Type 1-Infected Patients

M. Leal, J. Macías, J. Pineda, 1998, Journal of Clinical Microbiology.

Predictive factors influencing peak viral load drop in response to nucleoside reverse transcriptase inhibitors in antiretroviral-naive HIV-1-infected patients.

B. Clotet, L. Ruiz, C. Vidal, 1998, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

Comparison of Thymic Function-Related Markers to Predict Early Cd4 T-Cell Repopulation in Adult HIV-Infected Patients on Haart

E. Ruiz-Mateos, M. Leal, E. Lissen, 2002, Antiviral therapy.

T-cell changes after a short-term exposure to maraviroc in HIV-infected patients are related to antiviral activity.

E. Ruiz-Mateos, M. Leal, M. Genebat, 2012, The Journal of infection.

[Viral hepatitis in hemophiliac patients treated with commercial concentrates of factors VIII and IX].

M. Leal, E. Lissen, M. Miranda, 1985, Medicina clinica.

Immunological and virological effects of highly active antiretroviral therapy in two HIV‐1 infected children

M. Leal, E. Lissen, D. Gurbindo, 2000, Acta paediatrica.

Polyfunctional HIV-1 specific response by CD8+ T lymphocytes expressing high levels of CD300a

E. Ruiz-Mateos, M. Leal, F. Borrego, 2020, Scientific Reports.

Simplified sequence-specific oligonucleotide-based polymerase chain reaction protocol to characterize human major histocompatibility complex A*02 and A*24 specificities.

E. Ruiz-Mateos, M. Leal, M. González-Escribano, 2011, Human immunology.