S. Tazuma

发表

Relationships between Causes of Fever of Unknown Origin and Inflammatory Markers: A Multicenter Collaborative Retrospective Study.

K. Akazawa, K. Murakami, T. Naito, 2015, Internal medicine.

Efficacy of pitavastatin for the treatment of non‐alcoholic steatohepatitis with dyslipidemia: An open‐label, pilot study

Y. Matsuzaki, S. Tazuma, K. Inui, 2011, Hepatology research : the official journal of the Japan Society of Hepatology.

Efficacy of atorvastatin for the treatment of nonalcoholic steatohepatitis with dyslipidemia.

K. Chayama, K. Arihiro, S. Tazuma, 2008, Metabolism: clinical and experimental.

Bile Acids and Gallstones: Epidemiology, Pathogenesis, Diagnosis, and Management

S. Tazuma, 2017 .

Increased serum liver X receptor ligand oxysterols in patients with non-alcoholic fatty liver disease

T. Miyazaki, A. Honda, Y. Matsuzaki, 2012, Journal of Gastroenterology.

Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: studies in the gallstone-susceptible mouse.

S. Tazuma, D. Cohen, M. Carey, 2003, American journal of physiology. Gastrointestinal and liver physiology.

The mechanism of increased biliary lipid secretion in mice with genetic inactivation of bile salt export pump.

V. Ling, S. Tazuma, H. Verkade, 2015, American journal of physiology. Gastrointestinal and liver physiology.

GI-00391-2014 Revised The mechanism of increased biliary lipid secretion in mice with

V. Ling, S. Tazuma, B. Columbia., 2014 .

Transcytotic vesicle fusion with canalicular membranes is modulated by phospholipid species: Implications for biliary lipid secretion

S. Tazuma, G. Kajiyama, N. Hirano, 1997, Journal of gastroenterology and hepatology.

Partial Characterization of Mechanisms of Cytoprotective Action of Hydrophilic Bile Salts Against Hydrophobic Bile Salts in Rats (Relation to Canalicular Membrane Fluidity and Packing Density)

S. Tazuma, G. Kajiyama, H. Miyake, 2004, Digestive Diseases and Sciences.

Extracellular and Intracellular Regulation of Biliary Lecithin Hydrophobicity

S. Tazuma, G. Kajiyama, H. Miura, 2004, Digestive Diseases and Sciences.

Biliary excretory function is regulated by canalicular membrane fluidity associated with phospholipid fatty acyl chains in the bilayer: Implications for the pathophysiology of cholestasis

S. Tazuma, G. Kajiyama, H. Hyogo, 2000, Journal of gastroenterology and hepatology.

Effect of organic anions on acyl chain composition of secreted biliary lecithin in rats : relation to hepatocellular vesicle pathway

S. Tazuma, G. Kajiyama, H. Hyogo, 1997 .

Effect of cholestasis induced by organic anion on the lipid composition of hepatic membrane subfractions and bile in rats

S. Tazuma, G. Kajiyama, H. Miura, 1997, Journal of gastroenterology and hepatology.

Effects of pravastatin (CS-514) on biliary lipid metabolism in patients with hyperlipidemia.

S. Tazuma, G. Kajiyama, I. Horiuchi, 1991, Metabolism: clinical and experimental.

Which Has Superior Acid-Suppressive Effect, 10 Mg Omeprazole Once Daily or 20 Mg Famotidine Twice Daily? Effects of Single or Repeated Administration in Japanese Helicobacter Pylori-Negative CYP2C19 Extensive Metabolizers

J. Xu, S. Tazuma, K. Ikawa, 2007, Digestive Diseases and Sciences.

Fate of residual fragments after successful extracorporeal shock wave lithotripsy

S. Tazuma, Mutsuo Hayashi, H. Yasumoto, 1999, International journal of urology : official journal of the Japanese Urological Association.

Effects of cerivastatin sodium, a new HMG-CoA reductase inhibitor, on biliary lipid metabolism in patients with hypercholesterolemia.

S. Tazuma, G. Kajiyama, H. Hyogo, 1998, Clinical therapeutics.

Clinical practice guidelines for IgG4‐related sclerosing cholangitis

Masahiro Yoshida, M. Unno, T. Itoi, 2019, Journal of hepato-biliary-pancreatic sciences.

A case of giant cell arteritis simultaneously diagnosed with chronic subdural hematoma

Y. Otani, S. Tazuma, Tomoki Kobayashi, 2019, Clinical case reports.

16. Pathogenesis and Treatment of Gallstone Diseases

M. Mizooka, S. Tazuma, Keishi Kanno, 2013 .

Aging of hospital physicians in rural Japan: A longitudinal study based on national census data

S. Tazuma, S. Koike, M. Matsumoto, 2018, PloS one.

Clinical utility of computed tomography-based evaluation of trunk muscles in primary sclerosing cholangitis

K. Chayama, S. Tazuma, Kenichi Yoshimura, 2022, Japanese Journal of Radiology.

[110th Scientific Meeting of the Japanese Society of Internal Medicine: Educational lecture: 16. Pathogenesis and treatment of gallstone diseases].

M. Mizooka, S. Tazuma, Keishi Kanno, 2013, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine.

Gallstone disease: Epidemiology, pathogenesis, and classification of biliary stones (common bile duct and intrahepatic).

S. Tazuma, 2006, Best practice & research. Clinical gastroenterology.

An Atypical Case of Non-asthmatic Eosinophilic Granulomatosis with Polyangiitis Finally Diagnosed by Tissue Biopsy

Y. Otani, S. Tazuma, Tomoki Kobayashi, 2018, Internal medicine.

Lactobacillus plantarum SN13T Cells Improve Hepatic Dysfunction And Fecal Microbiota: A Randomized Pilot Study

N. Danshiitsoodol, M. Sugiyama, S. Tazuma, 2020 .

Recent understanding of cholesterol gallstone pathogenesis: implication to non-surgical therapeutic strategy

S. Tazuma, 2008, Clinical journal of gastroenterology.

Cholesterol gallstones

S. Tazuma, D. Cohen, H. Hyogo, 2002, Current opinion in gastroenterology.

Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells

K. Chayama, S. Tazuma, S. Yamagishi, 2008, Journal of Gastroenterology.

Carcinogenesis of malignant lesions of the gall bladder

S. Tazuma, G. Kajiyama, 2001, Langenbeck's Archives of Surgery.

A Ligand for Peroxisome Proliferator-Activated Receptor γ Inhibits Human Cholangiocarcinoma Cell Growth: Potential Molecular Targeting Strategy for Cholangioma

K. Chayama, S. Tazuma, H. Hyogo, 2006, Digestive Diseases and Sciences.

Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model

K. Chayama, S. Tazuma, K. Igarashi, 2010, Journal of clinical biochemistry and nutrition.

Deletion of angiotensin II type I receptor reduces hepatic steatosis.

K. Chayama, S. Tazuma, H. Hyogo, 2009, Journal of hepatology.

Bile Salt Hydrophobicity Modulates Subselection of Biliary Lecithin Species in Rats Depleted of Bile Salt Pool

S. Tazuma, G. Kajiyama, H. Miyake, 1998, Digestive Diseases and Sciences.

Less hydrophobic phosphatidylcholine species simplify biliary vesicle morphology, but induce bile metastability with a broad spectrum of crystal forms.

K. Chayama, S. Tazuma, M. Sakomoto, 2002, The Biochemical journal.

Role of bile salt hydrophobicity in distribution of phospholipid species to carriers in supersaturated model bile solutions

S. Tazuma, G. Kajiyama, G. Yamashita, 1999, Journal of gastroenterology and hepatology.

Partial characterization of proapoptotic action of biliary deteriorated lipids on biliary epithelial cells in pancreaticobiliary diseases

S. Tazuma, A. Sugiyama, K. Fujita, 2014, Journal of hepato-biliary-pancreatic sciences.

Transcytotic Vesicle Fusion Is Reduced in Cholestatic Rats (Redistribution of Phospholipids in the Canalicular Membrane)

S. Tazuma, G. Kajiyama, H. Hyogo, 1999, Digestive Diseases and Sciences.

Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis.

K. Chayama, M. Iwai, M. Horiuchi, 2006, Biochemical and biophysical research communications.

Protection against hydrophobic bile salt-induced cell membrane damage by liposomes and hydrophilic bile salts.

S. Tazuma, G. Kajiyama, H. Sagawa, 1993, The American journal of physiology.

Single Dose of OOCH Improves Mucosal T Helper Type 1/T Helper Type 2 Cytokine Balance and Prevents Experimental Colitis in the Presence of V&agr;14 Natural Killer T Cells in Mice

K. Chayama, T. Yamamura, S. Tazuma, 2005, Inflammatory bowel diseases.

Immune response in mouse experimental cholangitis associated with colitis induced by dextran sulfate sodium

K. Chayama, S. Tazuma, Y. Ueno, 2004, Journal of gastroenterology and hepatology.

Comparative effects on biliary concanavalin A-bound glycoproteins and calcium ion on cholesterol crystal nucleation and growth in model bile

S. Tazuma, G. Kajiyama, K. Teramen, 1995, Journal of Gastroenterology.

Modifying Hepatic Phospholipid Synthesis Associates with Biliary Phospholipid Secretion Rate in a Transporter-Independent Manner in Rats

S. Tazuma, G. Kajiyama, H. Ochi, 2001, Digestive Diseases and Sciences.

Choleretic action of diosgenin is based upon the increases in canalicular membrane fluidity and transporter activity mediating bile acid independent bile flow

K. Chayama, S. Tazuma, H. Ochi, 2003 .

Hydrophilic bile salts have a cytoprotective effect against cyclosporine A-induced cholestasis through enhanced canalicular membrane fluidity and transporter activity.

K. Chayama, S. Tazuma, H. Ochi, 2003, Hepatology research : the official journal of the Japan Society of Hepatology.

Bilirubin overload modulates bile canalicular membrane fluidity in rats: association with disproportionate reduction of biliary lipid secretion

S. Tazuma, G. Kajiyama, G. Yamashita, 2000, Journal of Gastroenterology.

Effects of bilirubin ditaurate on biliary secretion of proteins and lipids: Influence on the hepatic vesicle transport system

S. Tazuma, G. Kajiyama, G. Yamashita, 1999, Journal of gastroenterology and hepatology.

Method for quantitative assessment of transformation of non‐micellar cholesterol carriers in model bile systems *

S. Tazuma, G. Kajiyama, Y. Yamashita, 1996, Journal of gastroenterology and hepatology.

Osteodystrophy in Cholestatic Liver Diseases Is Attenuated by Anti-γ-Glutamyl Transpeptidase Antibody

S. Niida, T. Nakamoto, S. Tazuma, 2015, PloS one.

A combination therapy with simvastatin and ursodeoxycholic acid is more effective for cholesterol gallstone dissolution than is ursodeoxycholic acid monotherapy.

S. Tazuma, G. Kajiyama, F. Ueno, 1998, Journal of clinical gastroenterology.

Key diagnostic characteristics of fever of unknown origin in Japanese patients: a prospective multicentre study

K. Akazawa, T. Naito, H. Morita, 2019, BMJ Open.

Key diagnostic features of fever of unknown origin: Medical history and physical findings

M. Mizooka, S. Tazuma, Tomoki Kobayashi, 2017, Journal of general and family medicine.

Diagnostic workup for fever of unknown origin: a multicenter collaborative retrospective study

K. Akazawa, K. Murakami, T. Naito, 2013, BMJ Open.

Periostin antisense oligonucleotide prevents hepatic steatosis and fibrosis in a mouse model of non‐alcoholic steatohepatitis

Y. Otani, S. Tazuma, Tomoki Kobayashi, 2020, Journal of gastroenterology and hepatology.

Geographical distribution of family physicians in Japan: a nationwide cross-sectional study

S. Tazuma, S. Koike, M. Matsumoto, 2019, BMC Family Practice.

Depletion of hepatic stellate cells inhibits hepatic steatosis in mice

Y. Otani, S. Tazuma, Tomoki Kobayashi, 2022, Journal of gastroenterology and hepatology.

Administration of phosphatidylcholine-cholesterol liposomes partially reconstitutes fat absorption in chronically bile-diverted rats.

S. Tazuma, F. Kuipers, H. Verkade, 2004, Biochimica et biophysica acta.

Ursodeoxycholic acid is associated with improved long-term outcome in patients with primary sclerosing cholangitis

A. Tanaka, H. Takikawa, S. Tazuma, 2022, Journal of Gastroenterology.

Increase trend in the prevalence and male‐to‐female ratio of primary biliary cholangitis, autoimmune hepatitis, and primary sclerosing cholangitis in Japan

A. Tanaka, H. Ohira, H. Takikawa, 2019, Hepatology research : the official journal of the Japan Society of Hepatology.

Clinical guidelines for primary sclerosing cholangitis 2017

M. Unno, Y. Hirooka, T. Itoi, 2018, Journal of Gastroenterology.

Clinical diagnostic criteria of IgG4-related sclerosing cholangitis 2012

Y. Nakanuma, K. Uchida, K. Okazaki, 2012, Journal of hepato-biliary-pancreatic sciences.

Angiotensin II Participates in Hepatic Inflammation and Fibrosis through MCP-1 Expression

K. Chayama, S. Tazuma, H. Hyogo, 2005, Digestive Diseases and Sciences.

Donor age (≥45 years) and reduced immunosuppression are associated with the recurrent primary sclerosing cholangitis after liver transplantation – a multicenter retrospective study

K. Hasegawa, H. Ohdan, A. Tanaka, 2021, Transplant international : official journal of the European Society for Organ Transplantation.

Classification of biliary tract cancers established by the Japanese Society of Hepato‐Biliary‐Pancreatic Surgery: 3rd English edition

T. Takada, I. Endo, M. Miyazaki, 2015, Journal of hepato-biliary-pancreatic sciences.

Enhancing hepatic fibrosis in spontaneously hypertensive rats fed a choline‐deficient diet: a follow‐up report on long‐term effects of oxidative stress in non‐alcoholic fatty liver disease

K. Arihiro, S. Tazuma, A. Sugiyama, 2016, Journal of hepato-biliary-pancreatic sciences.

Spontaneously hypertensive rats develop pronounced hepatic steatosis induced by choline‐deficient diet: Evidence for hypertension as a potential enhancer in non‐alcoholic steatohepatitis

K. Arihiro, S. Tazuma, K. Fujita, 2012, Hepatology research : the official journal of the Japan Society of Hepatology.

Evolution of Hepatitis C Virus Quasispecies during Ribavirin and Interferon-Alpha-2b Combination Therapy and Interferon-Alpha-2b Monotherapy

K. Chayama, S. Tazuma, H. Kumada, 2006, Intervirology.

Prospective cohort study of fever incidence and risk in elderly persons living at home

S. Tazuma, M. Matsushima, Y. Fujinuma, 2014, BMJ Open.

Homocysteine and gallstone diseases: is hyperhomocysteinemia a prerequisite for or secondary to gallstone formation?

S. Tazuma, 2005, Journal of Gastroenterology.

Clinical utility of computed tomography-based evaluation of trunk muscles in primary sclerosing cholangitis

K. Chayama, S. Tazuma, Kenichi Yoshimura, 2022, Japanese Journal of Radiology.

Hydrophilic bile salts and liposomes inhibit hydrophobic bile salt‐induced release of glycoprotein by guinea‐pig gall‐bladder

S. Tazuma, G. Kajiyama, N. Aihara, 1995, Journal of gastroenterology and hepatology.

A quantitative assessment of serum chylomicron by light scattering intensity: Application to the intestinal fat absorption test

S. Tazuma, G. Kajiyama, H. Hyogo, 1997, Journal of gastroenterology and hepatology.

Statins affect gallstone diseases: Underlying mechanism(s) are to be established

S. Tazuma, 2015, Hepatology research : the official journal of the Japan Society of Hepatology.

Effects of long-term treatment with low-dose pravastatin on biliary lipid and bile acid composition in patients with nonfamilial hyperlipoproteinemia.

S. Tazuma, H. Ochi, K. Teramen, 1995, Metabolism: clinical and experimental.

Inhibitory effects of pravastatin, a competitive inhibitor of hydroxymethylglutaryl coenzyme A reductase, on cholesterol gallstone formation in prairie dogs.

S. Tazuma, G. Kajiyama, G. Yamashita, 1992, Digestion.

Protective effect of phosphatidylcholine on lysophosphatidylcholine‐induced cellular senescence in cholangiocyte

Y. Otani, S. Tazuma, Tomoki Kobayashi, 2019, Journal of hepato-biliary-pancreatic sciences.

Cholangiocyte senescence caused by lysophosphatidylcholine as a potential implication in carcinogenesis

S. Tazuma, A. Sugiyama, A. Araki, 2015, Journal of hepato-biliary-pancreatic sciences.

Elevated levels of serum advanced glycation end products in patients with non‐alcoholic steatohepatitis

K. Chayama, K. Arihiro, S. Tazuma, 2007, Journal of gastroenterology and hepatology.

Long‐term administration of a Niemann‐Pick C1‐like 1 inhibitor, ezetimibe, does not worsen bile lithogenicity in dyslipidemic patients with hepatobiliary diseases

M. Mizooka, S. Tazuma, A. Sugiyama, 2016, Journal of hepato-biliary-pancreatic sciences.

Clinical evaluation of ezetimibe on bile lithogenicity in humans: Use of transnasal endoscopy for bile sampling

M. Mizooka, S. Tazuma, A. Sugiyama, 2015, Hepatology research : the official journal of the Japan Society of Hepatology.

Glycochenodeoxycholate plays a carcinogenic role in immortalized mouse cholangiocytes via oxidative DNA damage.

K. Chayama, S. Tazuma, H. Hyogo, 2005, Free radical biology & medicine.

Unique Inhibition of Bile Salt-Induced Apoptosis by Lecithins and Cytoprotective Bile Salts in Immortalized Mouse Cholangiocytes

K. Chayama, S. Tazuma, H. Hyogo, 2003, Digestive Diseases and Sciences.

Gastric Acid Normosecretion Is Not Essential in the Pathogenesis of Mild Erosive Gastroesophageal Reflux Disease in Relation to Helicobacter pylori Status

S. Tazuma, T. Shimatani, M. Inoue, 2004, Digestive Diseases and Sciences.

Successful Treatment of Acute Chest Syndrome with Manual Exchange Transfusion in a Patient with Sickle Beta+-thalassemia

Y. Otani, M. Mizooka, S. Tazuma, 2019, Internal medicine.

Endoscopic approach in the diagnosis of high‐grade pancreatic intraepithelial neoplasia

S. Tazuma, K. Hanada, Takuya Yamamoto, 2022, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Long-standing diabetes mellitus increases concomitant pancreatic cancer risk in patients with intraductal papillary mucinous neoplasms

N. Toyota, S. Tazuma, H. Kohno, 2022, BMC gastroenterology.

No negative impact of serum IgG4 levels on clinical outcome in 435 patients with primary sclerosing cholangitis from Japan

A. Tanaka, H. Takikawa, S. Tazuma, 2017, Journal of hepato-biliary-pancreatic sciences.

Clinical profiles of patients with primary sclerosing cholangitis in the elderly

K. Okazaki, H. Tsubouchi, A. Tanaka, 2015, Journal of hepato-biliary-pancreatic sciences.

Nationwide survey for primary sclerosing cholangitis and IgG4‐related sclerosing cholangitis in Japan

K. Okazaki, H. Tsubouchi, A. Tanaka, 2014, Journal of hepato-biliary-pancreatic sciences.

Evidence-based clinical practice guidelines for cholelithiasis 2016

K. Sugano, M. Unno, Y. Nimura, 2017, Journal of Gastroenterology.

Periostin promotes malignant potential by induction of epithelial‐mesenchymal transition in intrahepatic cholangiocarcinoma

H. Ohdan, K. Izuhara, S. Tazuma, 2017, Hepatology communications.

Treatment of Pancreatic Stones With Extracorporeal Shock Wave Lithotripsy: Results of a Multicenter Survey

Y. Atomi, S. Tazuma, K. Inui, 2005, Pancreas.

Effect of ursodeoxycholic acid administration on nucleation time in human gallbladder bile.

S. Tazuma, G. Kajiyama, I. Horiuchi, 1989, Gastroenterology.

Effects of 16,16-dimethyl prostaglandin E2 on biliary mucous glycoprotein and gallstone formation in guinea pigs.

S. Tazuma, G. Kajiyama, H. Sasaki, 1993, Scandinavian journal of gastroenterology.

Inhibition of cholesterol crystallization under bilirubin deconjugation: partial characterization of mechanisms whereby infected bile accelerates pigment stone formation.

K. Chayama, S. Tazuma, T. Nishioka, 2003, Biochimica et biophysica acta.

Nucleation time and fatty acid composition of lecithin in human gallbladder bile.

S. Tazuma, G. Kajiyama, S. Hatsushika, 1993, Scandinavian journal of gastroenterology.

Role of Phospholipase A2 in Cholesterol Gallstone Formation Is Associated with Biliary Phospholipid Species Selection at the Site of Hepatic Excretion

S. Tazuma, G. Kajiyama, H. Hyogo, 2000, Digestive Diseases and Sciences.

Influence of cholesterol crystallization effector proteins on vesicle fusion in supersaturated model bile

S. Tazuma, G. Kajiyama, G. Yamashita, 1999, Journal of gastroenterology and hepatology.

The comparative potency of cholesterol crystallization‐effector proteins in supersaturated model bile systems: Association with vesicle transformation

S. Tazuma, G. Kajiyama, G. Yamashita, 1998, Journal of gastroenterology and hepatology.

Erythromelalgic Symptoms in Left Subclavian Artery Stenosis

Y. Otani, S. Tazuma, Keishi Kanno, 2020, Internal medicine.

Focal Neurological Symptoms at Initial Presentation Could Be a Potential Risk Factor for Poor Prognosis Among Patients With Multiple Brain Abscesses by Streptococcus anginosus Group: A Case Report With Literature Review

S. Tazuma, T. Tanabe, Daisuke Miyamori, 2022, Cureus.

Management for Pancreatolithiasis: A Japanese Multicenter Study

Y. Atomi, S. Tazuma, K. Inui, 2013, Pancreas.

Identification of rare polymerase variants of hepatitis B virus using a two‐stage PCR with peptide nucleic acid clamping

K. Chayama, S. Tazuma, Y. Kawakami, 2004, Journal of medical virology.

Lafutidine, a Newly Developed Antiulcer Drug, Elevates Postprandial Intragastric pH and Increases Plasma Calcitonin Gene-Related Peptide and Somatostatin Concentrations in Humans: Comparisons with Famotidine

J. Xu, S. Tazuma, K. Ikawa, 2006, Digestive Diseases and Sciences.

A Nuclear Receptor Ligand Down-Regulates Cytosolic Phospholipase A2 Expression to Reduce Bile Acid–Induced Cyclooxygenase 2 Activity in Cholangiocytes: Implications of Anticarcinogenic Action of Farnesoid X Receptor Agonists

K. Chayama, S. Tazuma, H. Hyogo, 2005, Digestive Diseases and Sciences.

Partial characterization of cytoprotective mechanisms of lecithin against bile salt-induced bile duct damage

K. Chayama, S. Tazuma, K. Tsuboi, 2004, Journal of Gastroenterology.

A proposed severity classification system for hepatolithiasis based on an analysis of prognostic factors in a Japanese patient cohort

Masaharu Kogure, A. Tanaka, H. Takikawa, 2018, Journal of Gastroenterology.

Ursodeoxycholic acid after bile duct stone removal and risk factors for recurrence: a randomized trial

S. Tazuma, K. Inui, S. Ryozawa, 2016, Journal of hepato-biliary-pancreatic sciences.

Cyclosporin A and cholestasis: Its mechanism(s) and clinical relevancy.

S. Tazuma, 2006, Hepatology research : the official journal of the Japan Society of Hepatology.

Toxocariasis Suspected of Having Infiltrated Directly from the Liver to the Lung through the Diaphragm

N. Furusyo, S. Tazuma, E. Ogawa, 2019, Internal medicine.

Acid-Suppressive Efficacy of a Reduced Dosage of Rabeprazole: Comparison of 10 Mg Twice Daily Rabeprazole with 20 Mg Twice Daily Rabeprazole, 30 Mg Twice Daily Lansoprazole, and 20 Mg Twice Daily Omeprazole by 24-Hr Intragastric pH-metry

J. Xu, S. Tazuma, T. Shimatani, 2005, Digestive Diseases and Sciences.

Acid‐suppressive effects of rabeprazole, omeprazole, and lansoprazole at reduced and standard doses: A crossover comparative study in homozygous extensive metabolizers of cytochrome P450 2C19

H. Mieno, J. Xu, S. Tazuma, 2006, Clinical pharmacology and therapeutics.

Prevalence of Helicobacter pylori infection, endoscopic gastric findings and dyspeptic symptoms among a young Japanese population born in the 1970s

S. Tazuma, M. Yokozaki, H. Hyogo, 2005, Journal of gastroenterology and hepatology.

Gastric Acidity in Patients with Follicular Gastritis is Significantly Reduced, but Can be Normalized After Eradication for Helicobacter pylori

S. Tazuma, M. Yokozaki, H. Hyogo, 2005, Helicobacter.

Clinical efficacy of intravenous ciprofloxacin in patients with biliary tract infection: a randomized controlled trial with carbapenem as comparator

S. Tazuma, K. Inui, H. Ohara, 2009, Journal of Gastroenterology.

Japanese guidelines for the endoscopic management of pancreatic stone

N. Sata, Y. Hirooka, S. Tazuma, 2010 .

Management of Pancreatolithiasis: A Nationwide Survey in Japan

Masafumi Nakamura, Y. Hirooka, A. Masamune, 2018, Pancreas.

Japanese Clinical Guidelines for Endoscopic Treatment of Pancreatolithiasis

N. Sata, Y. Hirooka, A. Irisawa, 2015, Pancreas.

Impaired gallbladder mucosal function in aged gallstone patients suppresses gallstone recurrence after successful extracorporeal shockwave lithotripsy

K. Chayama, S. Tazuma, H. Hyogo, 2003, Journal of gastroenterology and hepatology.

Repeated piezoelectric lithotripsy for gallstones with and without ursodeoxycholic acid dissolution: A multicenter study

S. Tazuma, H. Tanimura, G. Kajiyama, 1995, Journal of Gastroenterology.

Nutritional factors (nutritional aspects) in biliary disorders: Bile acid and lipid metabolism in gallstone diseases and pancreaticobiliary maljunction

S. Tazuma, A. Sugiyama, Keishi Kanno, 2013, Journal of gastroenterology and hepatology.

AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl(4).

K. Chayama, S. Tazuma, Keishi Kanno, 2003, Biochemical and biophysical research communications.

Cytoprotective effect of tauroursodeoxycholate on hepatocyte apoptosis induced by peroxisome proliferator‐activated receptor gamma ligand

K. Chayama, S. Tazuma, H. Hyogo, 2008, Journal of gastroenterology and hepatology.

A nuclear receptor-mediated choleretic action of fibrates is associated with enhanced canalicular membrane fluidity and transporter activity mediating bile acid-independent bile secretion.

K. Chayama, S. Tazuma, H. Hyogo, 2005, Journal of atherosclerosis and thrombosis.

Gallbladder Dysfunction Enhances Physical Density But Not Biochemical Metastability of Biliary Vesicles

S. Tazuma, G. Kajiyama, Y. Sunami, 2000, Digestive Diseases and Sciences.

Effect of beta-muricholic acid on the prevention and dissolution of cholesterol gallstones in C57L/J mice.

S. Tazuma, D. Q. Wang, 2002, Journal of lipid research.

Partial replacement of bile salts causes marked changes of cholesterol crystallization in supersaturated model bile systems.

S. Tazuma, G. Kajiyama, G. Yamashita, 1999, The Biochemical journal.

Lecithin hydrophobicity modulates the process of cholesterol crystal nucleation and growth in supersaturated model bile systems.

S. Tazuma, G. Kajiyama, H. Ochi, 1996, The Biochemical journal.

Effects of fluvastatin on humanbiliary lipids

S. Tazuma, G. Kajiyama, H. Tokumo, 1995 .

Effects of fluvastatin on human biliary lipids.

S. Tazuma, H. Tokumo, F. Hino, 1995, The American journal of cardiology.

Degree of fatty acyl chain unsaturation in biliary lecithin dictates cholesterol nucleation and crystal growth.

S. Tazuma, H. Ochi, K. Teramen, 1994, Biochimica et biophysica acta.

Transport of conjugated bilirubin and other organic anions in bile: relation to biliary lipid structures.

S. Tazuma, R. Holzbach, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Acid-suppressive effects of rabeprazole: comparing 10mg and 20mg twice daily in Japanese Helicobacter pylori-negative and -positive CYP2C19 extensive metabolisers.

S. Tazuma, T. Shimatani, M. Inoue, 2006, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Lack of adiponectin promotes formation of cholesterol gallstones in mice.

S. Kihara, T. Funahashi, I. Shimomura, 2010, Biochemical and biophysical research communications.

Stabilization of biliary lipid particles by ursodeoxycholic acid

S. Tazuma, G. Kajiyama, S. Mizuno, 1993, Digestive Diseases and Sciences.

Emigration of regional quota graduates of Japanese medical schools to non-designated prefectures: a prospective nationwide cohort study

S. Tazuma, T. Owaki, M. Matsumoto, 2019, BMJ Open.

Clinical diagnostic criteria for IgG4‐related sclerosing cholangitis 2020

A. Masamune, K. Okazaki, A. Tanaka, 2021, Journal of hepato-biliary-pancreatic sciences.

Clinical Features, Response to Treatment, and Outcomes of IgG4‐Related Sclerosing Cholangitis

T. Chiba, K. Okazaki, A. Tanaka, 2017, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

The 2016 diagnostic criteria for primary sclerosing cholangitis

A. Tanaka, H. Takikawa, S. Tazuma, 2017, Journal of Gastroenterology.

Unique reciprocal changes of hepatocellular membrane transporter expression and fluidity in rats with selective biliary obstruction.

K. Chayama, S. Niida, S. Tazuma, 2003, Hepatology research : the official journal of the Japan Society of Hepatology.

Predictive factors for subsequent intrahepatic cholangiocarcinoma associated with hepatolithiasis: Japanese National Cohort Study for 18 years

Masaharu Kogure, H. Takikawa, S. Tazuma, 2022, Journal of Gastroenterology.

Senescent hepatic stellate cells caused by deoxycholic acid modulates malignant behavior of hepatocellular carcinoma

K. Arihiro, Y. Otani, S. Tazuma, 2020, Journal of Cancer Research and Clinical Oncology.

Practice Guidelines for Primary Care of Acute Abdomen 2015

Masahiro Yoshida, T. Nishidate, K. Hirata, 2016, Journal of hepato-biliary-pancreatic sciences.

The Practice Guidelines for Primary Care of Acute Abdomen 2015

Masahiro Yoshida, T. Nishidate, K. Hirata, 2016, Japanese Journal of Radiology.

Ursodeoxycholic acid is associated with improved long-term outcome in patients with primary sclerosing cholangitis

A. Tanaka, H. Takikawa, S. Tazuma, 2022, Journal of Gastroenterology.

Five Cases of Familial Mediterranean Fever in Japan: The Relationship with MEFV Mutations

S. Yamasaki, K. Migita, Y. Otani, 2018, Internal medicine.

Long‐term outcomes of pediatric‐onset primary sclerosing cholangitis: A single‐center experience in Japan

A. Tanaka, H. Takikawa, S. Tazuma, 2019, Hepatology research : the official journal of the Japan Society of Hepatology.

Systemic Inflammatory Syndrome Associated with a Case of Jugular Paraganglioma.

M. Mizooka, S. Tazuma, Tomoki Kobayashi, 2016, Internal medicine.

Black Hairy Tongue Treated With Oral Antibiotics: A Case Report

M. Mizooka, S. Tazuma, M. Nakajima, 2015, Journal of the American Geriatrics Society.

Abstracts of selected papers presented at the 33rd annual meeting of the japanese society of gastroenterology

A. Munakata, S. Iwane, M. Makuuchi, 2007, Gastroenterologia Japonica.

Factors Affecting Gallstone Recurrence After Successful Extracorporeal Shock Wave Lithotripsy

S. Tazuma, H. Hyogo, H. Ochi, 2000, Journal of clinical gastroenterology.

Decrease in major secondary bile acid, hyodeoxycholic acid, was the main alteration in hepatic bile acid compositions in a hypertensive nonalcoholic fatty liver disease model

H. Nittono, S. Tazuma, H. Takei, 2019, Journal of hepato-biliary-pancreatic sciences.

Bile Acid Reflux and Possible Inhibition of Helicobacter pylori Infection in Subjects Without Gastric Surgery

S. Tazuma, M. Inoue, Y. Kawai, 2001, Digestive Diseases and Sciences.

General practice departments of university hospitals and certified training programs for general practitioners in Japan: A nationwide questionnaire survey

M. Mizooka, S. Tazuma, M. Matsumoto, 2017, Journal of general and family medicine.

Association between Social Relationship and Glycemic Control among Older Japanese: JAGES Cross-Sectional Study

I. Kawachi, N. Kondo, S. Tazuma, 2017, PloS one.

Periostin promotes hepatic fibrosis in mice by modulating hepatic stellate cell activation via αv integrin interaction

K. Izuhara, S. Tazuma, S. Ohta, 2016, Journal of Gastroenterology.

Clinical features of hepatolithiasis: analyses of multicenter-based surveys in Japan

Y. Nakanuma, S. Tazuma, 2015, Lipids in Health and Disease.

Report on the 2013 national cholelithiasis survey in Japan

S. Tazuma, K. Inui, T. Kamisawa, 2015, Journal of hepato-biliary-pancreatic sciences.

Geographic Distribution of Regional Quota Program Graduates of Japanese Medical Schools: A Nationwide Cohort Study.

S. Tazuma, T. Owaki, M. Matsumoto, 2019, Academic medicine : journal of the Association of American Medical Colleges.

Adoption of Hospitalist Care in Asia: Experiences From Singapore, Taiwan, Korea, and Japan.

Arpana R. Vidyarthi, T. Naito, S. Tazuma, 2021, Journal of hospital medicine.

Geographic Maldistribution of Physicians in Japan : Increasing the Number of Generalists is One Solution

S. Tazuma, M. Matsumoto, K. Takeuchi, 2015 .

Reversibility of organic anion‐induced cholestasis: Association with compensatory hypersecretion of biliary phospholipid and protein in the dog

S. Tazuma, G. Kajiyama, H. Tokumo, 1994, Journal of gastroenterology and hepatology.

Cavernous hemangioma in the ascending colon treated by endoscopic mucosal resection

K. Chayama, K. Haruma, H. Kusunoki, 2007, Journal of Gastroenterology and Hepatology.

Hepatitis C Virus Core Protein Modulates Fatty Acid Metabolism and Thereby Causes Lipid Accumulation in the Liver

K. Chayama, S. Tazuma, H. Hyogo, 2005, Digestive Diseases and Sciences.

Acute respiratory distress syndrome caused by salicylate intoxication

Y. Otani, S. Tazuma, Keishi Kanno, 2018, Clinical Case Reports.

Detection Strategies and Examination of Early Pancreatic Cancer

S. Tazuma, K. Hanada, K. Kurihara, 2021, Management of Pancreatic Cancer and Cholangiocarcinoma.

A Case of Paraneoplastic Syndrome Mimicking Adult Still's Disease Caused by Rectal Cancer

H. Egi, H. Ohdan, S. Tazuma, 2013, Journal of the American Geriatrics Society.

Phospholipid Alterations in Hepatocyte Membranes and Transporter Protein Changes in Cholestatic Rat Model

Kuniharu Nakai, S. Tazuma, G. Kajiyama, 2001, Digestive Diseases and Sciences.

Fatty acid composition of lecithin is a key factor in bile metastability in supersaturated model bile systems.

S. Tazuma, G. Kajiyama, S. Tao, 1993, Biochimica et biophysica acta.

Clinical efficacy of intravenous doripenem in patients with acute biliary tract infection: a multicenter, randomized, controlled trial with imipenem/cilastatin as comparator

S. Tazuma, K. Inui, S. Ryozawa, 2015, Journal of Gastroenterology.

Clinical efficacy of i.v. doripenem, a new class of carbapenem, in patients with biliary tract infection: A multicenter trial

S. Tazuma, K. Inui, S. Ryozawa, 2011, Hepatology Research.

Primary Signet Ring Cell Carcinoma of Rectum Diagnosed by Boring Biopsy in Combination with Endoscopic Mucosal Resection

K. Arihiro, Y. Otani, M. Mizooka, 2018, Case reports in medicine.

Results of physician licence examination and scholarship contract compliance by the graduates of regional quotas in Japanese medical schools: a nationwide cross-sectional survey

S. Tazuma, T. Owaki, M. Matsumoto, 2017, BMJ Open.

[Crigler-Najjar syndrome (types I and II)].

S. Tazuma, G. Kajiyama, T. Nakanishi, 1995, Ryoikibetsu shokogun shirizu.

Abstracts of Selected Papers Presented at the 31st Annual Meeting of the Japanese Society of Gastroenterology

Y. Imai, K. Tanikawa, N. Tanaka, 2007, Gastroenterologia Japonica.

Development and Evaluation of Software to Simulate Clinical Training in Primary Care for Outpatients at Department of Pharmacotherapy, Hiroshima University Hopsital

S. Tazuma, M. Yokozaki, K. Ikawa, 2006 .

Clinical features of hepatolithiasis: analyses of multicenter-based surveys in Japan

Y. Nakanuma, S. Tazuma, 2015, Lipids in Health and Disease.

Web-Based Evaluation System to Measure Learning Effectiveness in Kampo Medicine

N. Iizuka, Y. Hamamoto, S. Tazuma, 2016, Evidence-based complementary and alternative medicine : eCAM.

Acid-Suppressive Effects of Various Regimens of Omeprazole in Helicobacter pylori-Negative CYP2C19 Homozygous Extensive Metabolizers: Which Regimen Has the Strongest Effect?

S. Tazuma, T. Shimatani, M. Inoue, 2007, Digestive Diseases and Sciences.

Follow-up study of the regional quota system of Japanese medical schools and prefecture scholarship programmes: a study protocol

S. Tazuma, J. Tanaka, T. Owaki, 2016, BMJ Open.

Wisteria floribunda agglutinin-sialylated mucin core polypeptide 1 is a sensitive biomarker for biliary tract carcinoma and intrahepatic cholangiocarcinoma: a multicenter study

Masakazu Yamamoto, A. Kuno, M. Unno, 2016, Journal of Gastroenterology.

Comparing the Acid-Suppressive Effects of Three Brands of Generic Lansoprazole with the Original: Pharmacokinetic Bioequivalence Tests Do Not Necessarily Guarantee Pharmacodynamic Equivalence

S. Tazuma, T. Shimatani, M. Inoue, 2009, Digestive Diseases and Sciences.

Acid-suppressive effects of generic omeprazole: comparison of three brands of generic omeprazole with original omeprazole.

H. Mieno, S. Tazuma, T. Shimatani, 2006, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Abstracts of Selected Papers Presented at the 76th GeneralMeeting of the Japanese Society of Gastroenterology

A. Munakata, S. Futagawa, K. Tanikawa, 2007, Gastroenterologia Japonica.

Gallstone disease: Epidemiology, pathogenesis, and classification of biliary stones (common bile duct and intrahepatic).

S. Tazuma, 2006, Best practice & research. Clinical gastroenterology.

[A study on the mechanisms whereby apolipoprotein A-1 (apo A-1) inhibits cholesterol crystal nucleation in human gallbladder bile].

S. Tazuma, G. Kajiyama, G. Yamashita, 1991, Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology.

[Effects of a competitive inhibitor of hydroxymethylglutaryl coenzyme A reductase on cholesterol gallstone formation in prairie dogs].

S. Tazuma, G. Yamashita, S. Hatsushika, 1991, Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology.

Dose-Dependent Conjugation of Sulfobromophthalein and Hepatic Transit Time in Bile Fistula Rats

K. Chayama, S. Tazuma, H. Ochi, 2001, Digestive Diseases and Sciences.

Cyclosporin A reduces canalicular membrane fluidity and regulates transporter function in rats.

K. Chayama, S. Tazuma, G. Kajiyama, 2001, The Biochemical journal.

Tauroursodeoxycholate and taurochenodeoxycholate stabilize bile lipid metastability through different mechanisms: relation to phospholipid fatty acid composition

S. Tazuma, G. Kajiyama, H. Hyogo, 1997 .

An estimation of human bile metastability: Clinical application of a sensitive cholesterol crystal growth assay

S. Tazuma, G. Kajiyama, H. Ochi, 1994, Journal of gastroenterology and hepatology.

Simultaneous microanalysis of biliary cholesterol, bile acids and fatty acids in lecithin using capillary column gas chromatography: an advantage to assess bile lithogenecity.

S. Tazuma, H. Ochi, K. Teramen, 1994, Journal of chromatography. B, Biomedical applications.

Classification of biliary tract cancers established by the Japanese Society of Hepato‐Biliary‐Pancreatic Surgery: 3rd English edition

T. Takada, I. Endo, M. Miyazaki, 2015, Journal of hepato-biliary-pancreatic sciences.

Efficacy of pitavastatin for the treatment of non‐alcoholic steatohepatitis with dyslipidemia: An open‐label, pilot study

Y. Matsuzaki, S. Tazuma, K. Inui, 2011, Hepatology research : the official journal of the Japan Society of Hepatology.

Deletion of angiotensin II type I receptor reduces hepatic steatosis.

K. Chayama, S. Tazuma, H. Hyogo, 2009, Journal of hepatology.

Spontaneously hypertensive rats develop pronounced hepatic steatosis induced by choline‐deficient diet: Evidence for hypertension as a potential enhancer in non‐alcoholic steatohepatitis

K. Arihiro, S. Tazuma, K. Fujita, 2012, Hepatology research : the official journal of the Japan Society of Hepatology.

Acute respiratory distress syndrome caused by salicylate intoxication

Y. Otani, S. Tazuma, Keishi Kanno, 2018, Clinical case reports.

Retrospective cohort study of the incidence and risk of fever in elderly people living at home: A pragmatic aspect of home medical management in Japan

S. Tazuma, M. Matsushima, Y. Fujinuma, 2013, Geriatrics & gerontology international.

Efficacy of Endoscopic Ultrasonography in the Diagnosis of Lateral Lymphatic Spread in Rectal Cancer

K. Dohi, T. Asahara, M. Okajima, 1996 .

Roles considered important for hospitalist and non-hospitalist generalist practice in Japan: a survey study

T. Naito, S. Tazuma, K. Nagasaki, 2023, BMC Primary Care.

Cholangiocyte senescence caused by lysophosphatidylcholine as a potential implication in carcinogenesis

S. Tazuma, A. Sugiyama, A. Araki, 2015, Journal of hepato-biliary-pancreatic sciences.

Abstracts of selected papers presented at the 34th annual meeting of the japanese society of gastroenterology

H. Tokumura, M. Ebara, K. Tanikawa, 1993, Gastroenterologia Japonica.

Choleretic action of diosgenin is based upon the increases in canalicular membrane fluidity and transporter activity mediating bile acid independent bile flow.

K. Chayama, S. Tazuma, H. Ochi, 2001, Hepatology research : the official journal of the Japan Society of Hepatology.