A. Chenal

发表

D. Ladant, A. Chenal, Ana-Cristina Sotomayor-Pérez, 2015 .

Stability, structural and functional properties of a monomeric, calcium–loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis

D. Ladant, P. Vachette, A. Chenal, 2017, Scientific Reports.

Bordetella pertussis adenylate cyclase toxin translocation across a tethered lipid bilayer

J. Devoisselle, D. Ladant, A. Chenal, 2013, Proceedings of the National Academy of Sciences.

Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis

D. Ladant, P. Vachette, S. Brier, 2017, PLoS biology.

The Translocation Domain of Botulinum Neurotoxin A Moderates the Propensity of the Catalytic Domain to Interact with Membranes at Acidic pH

S. Zinn-Justin, Javier Perez, A. Chenal, 2013, PloS one.

Concerted Protonation of Key Histidines Triggers Membrane Interaction of the Diphtheria Toxin T Domain*

A. Ménez, A. Chenal, D. Gillet, 2007, Journal of Biological Chemistry.

Membrane Interaction of Botulinum Neurotoxin A Translocation (T) Domain

A. Chenal, D. Gillet, H. Vitrac, 2008, Journal of Biological Chemistry.

Bacterial kinesin light chain (Bklc) links the Btub cytoskeleton to membranes

B. Raynal, A. Chenal, C. Janke, 2017, Scientific Reports.

STRUCTURE AND FUNCTION OF DIPHTHERIA TOXIN: FROM PATHOLOGY TO ENGINEERING

A. Chenal, D. Gillet, P. Nizard, 2002 .

Defining the interacting regions between apomyoglobin and lipid membrane by hydrogen/deuterium exchange coupled to mass spectrometry.

P. Man, A. Chenal, V. Forge, 2007, Journal of molecular biology.

Interactions of apomyoglobin with membranes: Mechanisms and effects on heme uptake

A. Chenal, H. Vitrac, V. Forge, 2007, Protein science : a publication of the Protein Society.

A high-affinity calmodulin-binding site in the CyaA toxin translocation domain is essential for invasion into eukaryotic cells

D. Ladant, P. Vachette, B. Raynal, 2020, bioRxiv.

Translocation and calmodulin-activation of the adenylate cyclase toxin (CyaA) of Bordetella pertussis

Johanna C. Karst, D. Ladant, P. Vachette, 2018, Pathogens and disease.

Bioengineering of Bordetella pertussis Adenylate Cyclase Toxin for Antigen-Delivery and Immunotherapy

D. Ladant, A. Chenal, 2018, Toxins.

Identification of a Region That Assists Membrane Insertion and Translocation of the Catalytic Domain of Bordetella pertussis CyaA Toxin*

Johanna C. Karst, D. Ladant, M. Swann, 2012, The Journal of Biological Chemistry.

Calcium-induced folding and stabilization of the intrinsically disordered RTX domain of the CyaA toxin.

A. Woźniak, Johanna C. Karst, D. Ladant, 2010, Biophysical journal.

CHAPTER 60 – Engineering of bacterial toxins for research and medicine

A. Ménez, A. Chenal, D. Gillet, 2006 .

Anchoring Sites of Fibrillogenic Peptide Hormone Somatostatin-14 on Plasmonic Nanoparticles

S. Sánchez‐Cortés, J. García-Ramos, A. Chenal, 2015 .

Secondary structure reshuffling modulates glycosyltransferase function at the membrane.

P. Alzari, D. Giganti, A. Chenal, 2015, Nature chemical biology.

Development of Conformational Antibodies to Detect Bcl-xL’s Amyloid Aggregates in Metal-Induced Apoptotic Neuroblastoma Cells

A. Chenal, C. Almunia, V. Forge, 2020, International journal of molecular sciences.

From bulk to plasmonic nanoparticle surfaces: the behavior of two potent therapeutic peptides, octreotide and pasireotide.

S. Sánchez‐Cortés, A. Chenal, Y. Coïc, 2016, Physical chemistry chemical physics : PCCP.

Synthesis and characterization of tethered lipid assemblies for membrane protein reconstitution (Review).

D. Ladant, A. Chenal, Rémi Veneziano, 2017, Biointerphases.

Dynamics and structural changes of calmodulin upon interaction with the antagonist calmidazolium

D. Ladant, P. Vachette, A. Mechaly, 2022, BMC biology.

Hydrogen/Deuterium Exchange Mass Spectrometry for the Structural Analysis of Detergent-Solubilized Membrane Proteins.

S. Brier, A. Chenal, Darragh P. O’Brien, 2020, Methods in molecular biology.

The catalytic domains of Clostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid

D. Lacy, A. Blondel, A. Chenal, 2015, Cellular microbiology.

Deciphering membrane insertion of the diphtheria toxin T domain by specular neutron reflectometry and solid-state NMR spectroscopy.

M. Ferrand, A. Chenal, C. Aisenbrey, 2009, Journal of molecular biology.

Anchoring Cytokines to Tumor Cells for the Preparation of Anticancer Vaccines Without Gene Transfection in Mice

A. Chenal, D. Gillet, P. Nizard, 2003, Journal of immunotherapy.

Prolonged display or rapid internalization of the IgG-binding protein ZZ anchored to the surface of cells using the diphtheria toxin T domain.

A. Chenal, D. Gillet, P. Nizard, 2001, Protein engineering.

Characterization of the regions involved in the calcium-induced folding of the intrinsically disordered RTX motifs from the bordetella pertussis adenylate cyclase toxin.

Johanna C. Karst, D. Ladant, A. Chenal, 2010, Journal of molecular biology.

Allosteric Activation of Bordetella pertussis Adenylyl Cyclase by Calmodulin

T. Malliavin, D. Ladant, A. Chenal, 2014, The Journal of Biological Chemistry.

New tool for visualizing and detecting Klebsiella pneumoniae infections

S. Etienne-Manneville, A. Chenal, C. Saveanu, 2017 .

A Robust and Sensitive Spectrophotometric Assay for the Enzymatic Activity of Bacterial Adenylate Cyclase Toxins

D. Ladant, A. Chenal, Marilyne Davi, 2022, Toxins.

Clostridium septicum alpha-toxin forms pores and induces rapid cell necrosis.

R. Benz, A. Chenal, O. Knapp, 2010, Toxicon : official journal of the International Society on Toxinology.

Correction: The Translocation Domain of Botulinum Neurotoxin A Moderates the Propensity of the Catalytic Domain to Interact with Membranes at Acidic pH

S. Zinn-Justin, Javier Perez, A. Chenal, 2016, PloS one.

Mean net charge of intrinsically disordered proteins: experimental determination of protein valence by electrophoretic mobility measurements.

Johanna C. Karst, D. Ladant, A. Chenal, 2012, Methods in molecular biology.

Estimation of intrinsically disordered protein shape and time-averaged apparent hydration in native conditions by a combination of hydrodynamic methods.

Johanna C. Karst, D. Ladant, A. Chenal, 2012, Methods in molecular biology.

Characterization of Wild-Type Recombinant Bet v 1a as a Candidate Vaccine against Birch Pollen Allergy

R. Valenta, P. Valent, A. Chenal, 2005, International Archives of Allergy and Immunology.

Molecular crowding stabilizes both the intrinsically disordered calcium-free state and the folded calcium-bound state of a repeat in toxin (RTX) protein.

D. Ladant, A. Chenal, Ana-Cristina Sotomayor-Pérez, 2013, Journal of the American Chemical Society.

Calmodulin-induced conformational and hydrodynamic changes in the catalytic domain of Bordetella pertussis adenylate cyclase toxin.

Johanna C. Karst, D. Ladant, B. Raynal, 2010, Biochemistry.

Functional and structural consequences of epithelial cell invasion by Bordetella pertussis adenylate cyclase toxin

D. Ladant, M. Filoche, A. Chenal, 2020, bioRxiv.

Alteration of the tertiary structure of the major bee venom allergen Api m 1 by multiple mutations is concomitant with low IgE reactivity

M. Gelb, A. Ménez, B. Maillère, 2004, Protein science : a publication of the Protein Society.

Clostridium perfringens Iota Toxin

Leonard A. Smith, A. Chenal, D. Gillet, 2002, The Journal of Biological Chemistry.

Novel cancer vaccines prepared by anchoring cytokines to tumor cells avoiding gene transfection

Philippe Nizard, David-Alexandre Gross, Alexandre Chenal, 2002, SPIE BiOS.

Structural disorder and induced folding within two cereal, ABA stress and ripening (ASR) proteins

S. Longhi, S. Brier, A. Chenal, 2017, Scientific Reports.

Type III secretion effectors of the IpaH family are E3 ubiquitin ligases.

A. Breitkreutz, P. Sansonetti, A. Chenal, 2007, Cell host & microbe.

Bee venom phospholipase A2 as a membrane-binding vector for cell surface display or internalization of soluble proteins.

A. Chenal, D. Gillet, C. Almunia, 2016, Toxicon : official journal of the International Society on Toxinology.

Exposure to Bordetella pertussis adenylate cyclase toxin affects integrin‐mediated adhesion and mechanics in alveolar epithelial cells

G. Pelle, D. Ladant, M. Filoche, 2017, Biology of the cell.

Dissecting the Structural and Chemical Determinants of the "Open-to-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria.

D. Giganti, A. Marina, J. Cifuente, 2020, Biochemistry.

Conformational states and thermodynamics of alpha-lactalbumin bound to membranes: a case study of the effects of pH, calcium, lipid membrane curvature and charge.

P. Savarin, A. Chenal, D. Gillet, 2005, Journal of molecular biology.

Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracis*

B. Bishop, Wei-Jen Tang, E. Chang, 2009, Journal of Biological Chemistry.

RTX Calcium Binding Motifs Are Intrinsically Disordered in the Absence of Calcium

M. Delepierre, D. Ladant, B. Raynal, 2009, Journal of Biological Chemistry.

Membrane Protein Insertion Regulated by Bringing Electrostatic and Hydrophobic Interactions into Play

P. Savarin, A. Chenal, D. Gillet, 2002, The Journal of Biological Chemistry.

MEMHDX: an interactive tool to expedite the statistical validation and visualization of large HDX-MS datasets

Stevenn Volant, Julia Chamot-Rooke, Alexandre Chenal, 2016, Bioinform..

The Adenylate Cyclase (CyaA) Toxin from Bordetella pertussis Has No Detectable Phospholipase A (PLA) Activity In Vitro

D. Ladant, A. Chenal, Mariette Matondo, 2019, Toxins.

Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough.

Johanna C. Karst, D. Ladant, P. Vachette, 2018, Toxicon : official journal of the International Society on Toxinology.

Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion

Julia Chamot-Rooke, Alexandre Chenal, Véronique Hourdel, 2015, Scientific Reports.

Structural and Functional Characterization of an Essential RTX Subdomain of Bordetella pertussis Adenylate Cyclase Toxin*

R. Benz, A. Chaffotte, D. Ladant, 2006, Journal of Biological Chemistry.

The Tip of the Four N-Terminal α-Helices of Clostridium sordellii Lethal Toxin Contains the Interaction Site with Membrane Phosphatidylserine Facilitating Small GTPases Glucosylation

A. Blondel, A. Chenal, B. Baron, 2016, Toxins.

Biophysical investigations of the adenylate cyclase (CyaA) toxin from Bordetella pertussis

Johanna C. Karst, D. Ladant, B. Raynal, 2016 .

Deciphering protein membrane interactions involved in the translocation process of a bacterial toxin, the adenylate cyclase (CyaA) toxin from Bordetella pertussis

Johanna C. Karst, D. Ladant, A. Chenal, 2016 .

Interaction between the two subdomains of the C‐terminal part of the botulinum neurotoxin A is essential for the generation of protective antibodies

A. Chenal, M. Tavallaie, D. Gillet, 2004, FEBS letters.

Behavior of the N-terminal helices of the diphtheria toxin T domain during the successive steps of membrane interaction.

A. Ménez, A. Chenal, D. Gillet, 2007, Biochemistry.

Dynamics and structural changes of calmodulin upon interaction with its potent antagonist calmidazolium

D. Ladant, P. Vachette, A. Mechaly, 2022, bioRxiv.

Does fusion of domains from unrelated proteins affect their folding pathways and the structural changes involved in their function? A case study with the diphtheria toxin T domain.

Philippe Nizard, Alexandre Chenal, Daniel Gillet, 2002, Protein engineering.

Characterization of a Membrane-active Peptide from the Bordetella pertussis CyaA Toxin*

D. Ladant, A. Chenal, Ana-Cristina Sotomayor-Pérez, 2013, The Journal of Biological Chemistry.

Disorder-to-Order Transition in the CyaA Toxin RTX Domain: Implications for Toxin Secretion

D. Ladant, A. Chenal, Ana-Cristina Sotomayor-Pérez, 2014, Toxins.

Molecular Basis of Membrane Association by the Phosphatidylinositol Mannosyltransferase PimA Enzyme from Mycobacteria*

P. Alzari, A. Chenal, M. Guerin, 2016, The Journal of Biological Chemistry.

Large size citrate‐reduced gold colloids appear as optimal SERS substrates for cationic peptides

S. Sánchez‐Cortés, J. García-Ramos, A. Chenal, 2017 .

Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum

P. Alzari, M. VanNieuwenhze, A. Chenal, 2019, Nature Communications.

Calcium-induced Folding of Intrinsically Disordered Repeat-in-Toxin (RTX) Motifs via Changes of Protein Charges and Oligomerization States*

Alexandre Chenal, Daniel Ladant, D. Ladant, 2011, The Journal of Biological Chemistry.

Amyloid fibrils formed by the programmed cell death regulator Bcl-xL.

B. Salin, Johanna C. Karst, C. Blanchet, 2012, Journal of molecular biology.

Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region

D. Ladant, A. Chenal, Nicolas Sapay, 2017, Toxins.

A High‐Affinity Calmodulin‐Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells

D. Ladant, P. Vachette, B. Raynal, 2021, Advanced science.

Gallocin A, an Atypical Two-Peptide Bacteriocin with Intramolecular Disulfide Bonds Required for Activity

T. Cokelaer, S. Dramsi, A. Chenal, 2023, bioRxiv.

Gallocin A, an atypical two-peptide bacteriocin secreted by Streptococcus gallolyticus subsp. gallolyticus

T. Cokelaer, S. Dramsi, A. Chenal, 2022 .

SEC‐SAXS and HDX‐MS: A powerful combination. The case of the calcium‐binding domain of a bacterial toxin

D. Ladant, P. Vachette, S. Brier, 2018, Biotechnology and applied biochemistry.

Calcium, Acylation, and Molecular Confinement Favor Folding of Bordetella pertussis Adenylate Cyclase CyaA Toxin into a Monomeric and Cytotoxic Form*

Johanna C. Karst, D. Ladant, A. Chenal, 2014, The Journal of Biological Chemistry.

Side chain resonances in static oriented proton-decoupled 15N solid-state NMR spectra of membrane proteins.

A. Chenal, C. Aisenbrey, B. Bechinger, 2009, Journal of the American Chemical Society.