H. Apell

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Reviews of Physiology, Biochemistry and Pharmacology

H. Apell, 2003, Reviews of Physiology, Biochemistry and Pharmacology.

Role of protons in the pump cycle of KdpFABC investigated by time-resolved kinetic experiments.

H. Apell, Bojana Damnjanović, 2014, Biochemistry.

Specific volume and compressibility of bilayer lipid membranes with incorporated Na,K-ATPase.

T. Hianik, H. Apell, P. Rybár, 2011, General physiology and biophysics.

Kinetics of luminal proton binding to the SR Ca-ATPase.

H. Apell, A. Fibich, 2011, Biophysical journal.

Involvement of protons in the ion transport cycle of Na+,K+-ATPase

V. Y. Tashkin, H. Apell, K. O. Grishanin, 2010, Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology.

Investigation of electrogenic partial reactions in detergent-solubilized Na,K-ATPase.

M. Habeck, A. Katz, H. Apell, 2009, Biochemistry.

Kinetics of proton binding to the sarcoplasmic reticulum Ca-ATPase in the E1 state.

H. Apell, K. Janko, A. Fibich, 2007, Biophysical journal.

Palytoxin-induced Effects on Partial Reactions of the Na,K-ATPase

H. Apell, N. Harmel, 2006, The Journal of general physiology.

Electrogenic partial reactions of the gastric H,K-ATPase.

G. Sachs, H. Apell, O. Vagin, 2005, Biophysical journal.

Time-resolved charge movements in the sarcoplasmatic reticulum Ca-ATPase.

C. Peinelt, H. Apell, 2004, Biophysical journal.

Structure-function relationship in P-type ATPases--a biophysical approach.

H. Apell, H. Apell, 2003, Reviews of physiology, biochemistry and pharmacology.

Reviews of Physiology, Biochemistry and Pharmacology

H. Apell, 2003, Reviews of Physiology, Biochemistry and Pharmacology.

Toward an Understanding of Ion Transport through the Na,K‐ATPase

H. Apell, 2003, Annals of the New York Academy of Sciences.

Do H+ ions obscure electrogenic Na+ and K+ binding in the E1 state of the Na,K‐ATPase?

H. Apell, Anna Diller, 2002, FEBS letters.

Ion Selectivity of the Cytoplasmic Binding Sites of the Na,K-ATPase: II. Competition of Various Cations

H. Apell, A. Schneeberger, 2001, The Journal of Membrane Biology.

Reconstitution of Na+/K+-ATPase into phosphatidylcholine vesicles by dialysis of nonionic alkyl maltoside detergents.

R. Riek, H. Plattner, H. Apell, 1988, Biochimica et biophysica acta.

Assaying P-Type ATPases Reconstituted in Liposomes.

H. Apell, Bojana Damnjanović, 2016, Methods in molecular biology.

Mechanistic analysis of the pump cycle of the KdpFABC P-type ATPase.

H. Apell, A. Weber, Bojana Damnjanović, 2013, Biochemistry.

Investigation of reconstitution of the Na, K-ATPase in lipid vesicles.

R. Riek, H. Apell, Ivashchuk-Kienbaum YuA, 1993, Biochimica et biophysica acta.

A stopped-flow kinetic study of the interaction of potential-sensitive oxonol dyes with lipid vesicles.

H. Apell, R. Clarke, 1989, Biophysical chemistry.

(Na+ + K+)-ATPase in artificial lipid vesicles: influence of lipid structure on pumping rate.

R. Schwendener, M. M. Marcus, H. Apell, 1986, Biochimica et biophysica acta.

Partial Reactions of the Na,K-ATPase: Determination of Activation Energies and an Approach to Mechanism

H. Apell, M. Roudná, 2020, The Journal of Membrane Biology.

Kinetic and Energetic Aspects of Na+/K+‐Transport Cycle Steps a

H. Apell, 1997, Annals of the New York Academy of Sciences.

Electrogenic binding of ions at the cytoplasmic side of the Na+,K+-ATPase

V. Y. Tashkin, H. Apell, A. I. Ilovaisky, 2015, Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology.

Probing the extracellular access channel of the Na,K-ATPase.

H. Apell, R. Gradinaru, 2015, Biochemistry.

Extracellular allosteric Na(+) binding to the Na(+),K(+)-ATPase in cardiac myocytes.

H. Apell, H. Rasmussen, R. Clarke, 2013, Biophysical journal.

The competition transport of sodium ions and protons in the cytoplasmic access channel of the Na+,K+-ATPase

V. Y. Tashkin, H. Apell, V. Sokolov, 2013, Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology.

Photodynamic Inactivation of the Na,K-ATPase Occurs via Different Pathways

H. Apell, G. Stark, F. Killig, 2004, The Journal of Membrane Biology.

Molecular Mechanisms and Kinetic Effects of FXYD1 and Phosphomimetic Mutants on Purified Human Na,K-ATPase*

M. Habeck, Y. Peleg, M. Eisenstein, 2015, The Journal of Biological Chemistry.

Kinetics of the Interaction of the Potential-Sensitive Dye Oxonol V with Lipid Vesicles

H. Apell, R. Clarke, 1990 .

Fast charge translocations associated with partial reactions of the Na,K-pump: I. Current and voltage transients after photochemical release of ATP

H. Apell, P. Läuger, R. Borlinghaus, 2005, The Journal of Membrane Biology.

Current transients generated by the Na+/K+-ATPase after an ATP concentration jump: dependence on sodium and ATP concentration.

H. Apell, R. Borlinghaus, 1988, Biochimica et biophysica acta.

Effects of surface charge on the conductance of the gramicidin channel.

E. Bamberg, H. Apell, P. Läuger, 1979, Biochimica et biophysica acta.

TtOmp85, a β-Barrel Assembly Protein, Functions by Barrel Augmentation

Jie Liang, Matthias Müller, W. Welte, 2014, Biochemistry.

A novel tumor necrosis factor-mediated mechanism of direct epithelial sodium channel activation.

Richard E. White, J. Pittet, A. Verin, 2014, American journal of respiratory and critical care medicine.

Formation of ionic channels in black lipid membranes by succinic derivatives of Gramicidin A

E. Bamberg, R. Bradley, H. Apell, 1979, The Journal of Membrane Biology.

Formation of ion channels by a negatively charged analog of gramicidin a

E. Bamberg, H. Apell, P. Läuger, 1977, The Journal of Membrane Biology.

Ion channels formed by chemical analogs of gramicidin A.

E. Bamberg, H. Apell, K. Janko, 1978, Federation proceedings.

Interaction of ATP with the phosphoenzyme of the Na+,K+-ATPase.

H. Apell, F. Cornelius, R. Clarke, 2010, Biochemistry.

Sequential potassium binding at the extracellular side of the Na,K-Pump

H. Apell, R. Bühler, H. -J. Apell, 1995, The Journal of Membrane Biology.

Investigation of ion binding to the cytoplasmic binding sites of the Na,K-pump

H. Apell, Susann Schulz, 2004, European Biophysics Journal.

Charge translocation by the Na,K-pump: II. Ion binding and release at the extracellular face

H. Apell, P. Läuger, W. Stürmer, 1991, The Journal of Membrane Biology.

Fast transient currents in Na,K-ATPase induced by ATP concentration jumps from the P3-[1-(3',5'-dimethoxyphenyl)-2-phenyl-2-oxo]ethyl ester of ATP.

J. Corrie, H. Apell, D. Trentham, 1998, Biophysical journal.

Investigation Of Electrogenic Partial Reactions In Detergent-solubilized Na,K-ATPase

M. Habeck, H. Apell, 2009 .

Chapter 12 Electrogenic Properties of the Na/K Pump: Voltage Dependence and Kinetics of Charge Translocation

H. Apell, P. Läuger, R. Borlinghaus, 1989 .

Voltage dependence of partial reactions of the Na+/K+ pump: predictions from microscopic models.

H. Apell, P. Läuger, 1988, Biochimica et biophysica acta.

Structure of the gramicidin A channel: discrimination between the piL,D and the beta helix by electrical measurements with lipid bilayer membranes.

E. Bamberg, H. Apell, H. Alpes, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Kinetic analysis of bacterial reaction centers reconstituted in lipid bilayers

H. Apell, R. Bachofen, M. Snozzi, 1983 .

Electrogenic transport of sodium ions in cytoplasmic and extracellular ion access channels of Na+,K+-ATPase probed by admittance measurement technique

H. Apell, Y. Chizmadzhev, A. A. Lenz, 2008, Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology.

Charge Translocation in a Single Turnover of the Na,K-pump

H. Apell, P. Läuger, R. Borlinghaus, 1988 .

(Na+ + K+)-ATPase in artificial lipid vesicles: influence of the concentration of mono- and divalent cations on the pumping rate.

M. M. Marcus, H. Apell, 1986, Biochimica et biophysica acta.

Electrogenic Partial Reactions of the SR-Ca-ATPase Investigated by a Fluorescence Method

H. Apell, M. Roudná, C. Butscher, 1999, The Journal of Membrane Biology.

Effects of the ATP, ADP and inorganic phosphate on the transport rate of the Na+,K+-pump.

M. Nelson, M. M. Marcus, H. Apell, 1986, Biochimica et biophysica acta.

Effect of clotrimazole on the pump cycle of the Na,K-ATPase.

H. Apell, F. Tadini-Buoninsegni, M. Moncelli, 2008, Biophysical journal.

Kinetics of Na(+)-dependent conformational changes of rabbit kidney Na+,K(+)-ATPase.

E. Bamberg, H. Apell, R. Clarke, 1998, Biophysical journal.

Kinetics of Na 1 -Dependent Conformational Changes of Rabbit Kidney Na 1 ,K 1 -ATPase

E. Bamberg, H. Apell, R. Clarke, 1998 .

Na,K-ATPase in crystalline form investigated by scanning force microscopy.

O. Marti, H. Apell, J. Colchero, 1992, Ultramicroscopy.

Allosteric effect of ATP on Na(+),K(+)-ATPase conformational kinetics.

H. Apell, R. Clarke, Benjamin Y Kong, 2007, Biochemistry.

Fast charge translocations associated with partial reactions of the Na,K-pump: II. Microscopic analysis of transient currents

H. Apell, P. Läuger, R. Borlinghaus, 2005, The Journal of Membrane Biology.

Conformational transitions and charge translocation by the Na,K pump: Comparison of optical and electrical transients elicited by ATP-concentration jumps

H. Apell, P. Läuger, W. Stürmer, 1989, The Journal of Membrane Biology.

Ion Translocation by the Na,K-Pump: Correlation between Electrogenic Events and Conformational Transitions

H. Apell, P. Läuger, W. Stürmer, 1990 .

Detection of Charge Movements in Ion Pumps by a Family of Styryl Dyes

H. Apell, M. Roudná, S. Beutner, 2002, The Journal of Membrane Biology.

How do P-type ATPases transport ions?

H. Apell, 2004, Bioelectrochemistry.

Polarized infrared absorption of Na+/K+-ATPase studied by attenuated total reflection spectroscopy.

H. Apell, P. Läuger, U. P. Fringeli, 1989, Biochimica et biophysica acta.

Photochemical Behavior and Na+,K+-ATPase Sensitivity of Voltage-sensitive Styrylpyridinium Fluorescent Membrane Probes

H. Apell, P. Sebban, M. McLeod, 2006, Photochemistry and photobiology.

Effect of chaotropic anions on the sodium transport by the Na,K-ATPase

H. Apell, A. Ayuyan, A. A. Lenz, 2006, European Biophysics Journal.

Pump current and Na+/K+ coupling ratio of Na+/K+-ATPase in reconstituted lipid vesicles.

H. Apell, P. Läuger, R. Clarke, 1989, Biochimica et biophysica acta.

Kinetics of Potential-Sensitive Fluorescent Dye Interaction with Lipid Vesicles and Application to the Measurement of Membrane Potential Transients Generated by the Na,K-Pump

H. Apell, R. Clarke, 1989 .

Lactosylceramides with Unsaturated Fatty Acids—Synthesis and Use in the Generation of Bilayer Membranes

H. Apell, R. Schmidt, T. Bär, 1987 .

Inhibition of the gastric H,K-ATPase by clotrimazole.

H. Apell, K. Munson, A. Witzke, 2010, Biochemistry.

Inactivation of the Na,K‐ATPase by radiation‐induced free radicals Evidence for a radical‐chain mechanism

H. Apell, G. Stark, K. Hitschke, 1994, FEBS letters.

Electrostatic coupling of ion pumps.

H. Apell, J. Nieto-Frausto, P. Lüger, 1992, Biophysical Journal.

Photocurrents generated by bacteriorhodopsin on planar bilayer membranes

E. Bamberg, H. Apell, N. Dencher, 1979, Biophysics of structure and mechanism.

Effects of Free Radicals on Partial Reactions of the Na,K-ATPase

H. Apell, G. Stark, M. Mense, 1997, The Journal of Membrane Biology.

Charge translocation by the Na,K-pump: I. Kinetics of local field changes studied by time-resolved fluorescence measurements

H. Apell, P. Läuger, W. Stürmer, 1991, The Journal of Membrane Biology.

Entrance port for Na(+) and K(+) ions on Na(+),K(+)-ATPase in the cytoplasmic loop between trans-membrane segments M6 and M7 of the alpha subunit. Proximity Of the cytoplasmic segment of the beta subunit.

H. Apell, A. Shainskaya, S. Karlish, 2000, The Journal of biological chemistry.

Electrogenic properties of the Na,K pump

H. Apell, 1989, The Journal of Membrane Biology.

Influence of sodium concentration on changes of membrane capacitance associated with the electrogenic ion transport by the Na,K-ATPase

H. Apell, V. Sokolov, A. S. Darmostuk, 1998, European Biophysics Journal.

Electromagnetic Fields and Calcium Signaling by the Voltage Dependent Anion Channel

H. Apell, V. Ullrich, 2021 .

Direct evidence for Ca++-induced lateral phase separation in black membranes of lipid mixtures by the analysis of gramicidin A single-channels

W. Knoll, H. Apell, H. Eibl, 2004, European Biophysics Journal.

Lateral order in mixed lipid bilayers and its influence on ion translocation by gramicidin: a model for the structure-function relationship in membranes.

W. Knoll, H. Apell, T. Henkel, 1989, Biochimie.

Amphipathic polymers: tools to fold integral membrane proteins to their active form.

Y. Gohon, J. Popot, T. Dahmane, 2006, Biochemistry.

The major outer membrane protein of Fusobacterium nucleatum (FomA) folds and inserts into lipid bilayers via parallel folding pathways.

Pål Puntervoll, Jörg H Kleinschmidt, W. Welte, 2006, Journal of molecular biology.

Fluorescence heterogeneity of tryptophans in Na,K-ATPase: evidences for temperature-dependent energy transfer.

A. Demchenko, H. Apell, M. Vincent, 1998, Biophysical chemistry.

Functional Properties of Na,K-ATPase, and Their Structural Implications, as Detected with Biophysical Techniques

H. Apell, S. Karlish, 2001, The Journal of Membrane Biology.

Purification and characterization of soluble CD21 from human plasma by affinity chromatography and density gradient centrifugation.

H. Apell, M. Masilamani, H. Illges, 2002, Journal of immunological methods.

Partial reactions of the Na,K-ATPase: determination of rate constants

H. Apell, W. Stürmer, S. Heyse, 1994, The Journal of general physiology.

Does the sodium pump have secret levels?

H. Apell, 2014, Biophysical journal.

Fluorescence study on cardiac glycoside binding to the Na,K‐pump Ouabain binding is associated with movement of electrical charge

H. Apell, W. Stürmer, H.-J. Apell, 1992, FEBS letters.

Transient behaviour of the Na+/K+-pump: microscopic analysis of nonstationary ion-translocation.

H. Apell, P. Läuger, H. Apell, 1988, Biochimica et biophysica acta.

Kinetics of Ca2+ binding to the SR Ca-ATPase in the E1 state.

C. Peinelt, H. Apell, 2005, Biophysical journal.

Kinetics of Ca 2 1 Binding to the SR Ca-ATPase in the E 1 State

C. Peinelt, H. Apell, 2005 .

ATP binding equilibria of the Na(+),K(+)-ATPase.

J. Matthews, H. Apell, P. Sebban, 2008, Biochemistry.

Ion Selectivity of the Cytoplasmic Binding Sites of the Na,K-ATPase: I. Sodium Binding is Associated with a Conformational Rearrangement

H. Apell, A. Schneeberger, 1999, The Journal of Membrane Biology.

Electrogenicity of the sodium transport pathway in the Na,K-ATPase probed by charge-pulse experiments.

H. Apell, I. Wuddel, 1995, Biophysical journal.

Dielectric Coefficients of the Extracellular Release of Sodium Ions

H. Apell, W. Stürmer, I. Wuddel, 1994 .

Interaction between cytoplasmic sodium binding sites and cardiotonic steroids

B. Schwappach, H. Apell, S. Karlish, 1994 .

Fluorescence spectroscopic studies on equilibrium dipole-relaxational dynamics of Na,K-ATPase.

A. Demchenko, H. Apell, B. Feddersen, 1993, Biophysical chemistry.

Anomalies in α-scattering and (3He, α) reactions on 40, 41Ca and the effect of cluster exchange

R. Betts, H. Apell, R. Santo, 1975 .

Surface Charges of the Membrane Crucially Affect Regulation of Na,K-ATPase by Phospholemman (FXYD1)

A. Katz, H. Apell, Erica Cirri, 2013, The Journal of Membrane Biology.

Phospholemman (FXYD1) raises the affinity of the human α1β1 isoform of Na,K-ATPase for Na ions.

N. Mishra, A. Katz, H. Apell, 2011, Biochemistry.

Correct folding of the beta-barrel of the human membrane protein VDAC requires a lipid bilayer.

Thomas Meins, Jörg H Kleinschmidt, K. Zeth, 2007, Journal of molecular biology.

Mechanism of the Na,K-ATPase Inhibition by MCS Derivatives

H. Apell, R. Stimac, F. Kerek, 2005, The Journal of Membrane Biology.

Quantitative calculation of the role of the Na(+),K(+)-ATPase in thermogenesis.

M. Catauro, H. Apell, H. Rasmussen, 2013, Biochimica et biophysica acta.

Subtle mutation, far-reaching effects

H. Apell, 2017, The Journal of general physiology.

A microscopic model for the current-voltage behaviour of the Na,K-pump

H. Apell, P. Läuger, 1986, European Biophysics Journal.

Kinetic comparisons of heart and kidney Na+,K(+)-ATPases.

H. Apell, H. Rasmussen, R. Clarke, 2012, Biophysical journal.

Modulation of the Na,K-ATPase by Magnesium Ions.

H. Apell, T. Hitzler, Grischa Schreiber, 2017, Biochemistry.

KdpFABC reconstituted in Escherichia coli lipid vesicles: substrate dependence of the transport rate.

H. Apell, Bojana Damnjanović, 2014, Biochemistry.

Proton diet for the sodium pump.

H. Apell, Gabriel Benz, Daniel Sauerbrunn, 2011, Biochemistry.

Mechanistic principles of ion transport in the Na,K-ATPase

H. Apell, 2017, Russian Journal of Electrochemistry.

Partial reactions of the Na,K-ATPase: kinetic analysis and transport properties.

H. Apell, V. Sokolov, A. Schneeberger, 1998, Acta physiologica Scandinavica. Supplementum.

Scanning force microscopy of diatom shells

O. Marti, H. Apell, J. Colchero, 1992 .

Investigation of the Na,K-ATPase by SFM

O. Marti, H. Apell, J. Colchero, 1993 .

Scanning force microscopical studies of the Na+/K+-ATPase

H. Apell, A. Linder, 1994 .

Mechanism of the rate-determining step of the Na(+),K(+)-ATPase pump cycle.

H. Apell, F. Cornelius, C. Lüpfert, 2002, Biochemistry.

Electrostatic Stabilization Plays a Central Role in Autoinhibitory Regulation of the Na+,K+-ATPase.

H. Khandelia, H. Apell, F. Cornelius, 2017, Biophysical journal.

Kinetics of K(+) occlusion by the phosphoenzyme of the Na(+),K(+)-ATPase.

H. Apell, F. Cornelius, R. Clarke, 2011, Biophysical journal.

Kinetic Investigations of the Mechanism of the Rate‐Determining Step of the Na+,K+‐ATPase Pump Cycle

H. Apell, F. Cornelius, C. Lüpfert, 2003, Annals of the New York Academy of Sciences.

Rate limitation of the Na(+),K(+)-ATPase pump cycle.

V. Pintschovius, H. Apell, F. Cornelius, 2001, Biophysical journal.

Novel polymer substrates for SFM investigations of living cells, biological membranes, and proteins.

H. Apell, U. Weiland, A. Linder, 1999, Journal of structural biology.

Kinetics of the phosphorylation of Na,K-ATPase by inorganic phosphate detected by a fluorescence method.

J. Corrie, H. Apell, D. Trentham, 1996, Biochemistry.

Binding of the third Na+ ion to the cytoplasmic side of the Na,K‐ATPase is electrogenic

H. Apell, W. Domaszewicz, 1999, FEBS letters.

Dicarboxylic acid analogs of Gramicidin A: Dimerization kinetics and single channel properties

E. Bamberg, H. Apell, H. Alpes, 1979, The Journal of Membrane Biology.

Studies on the Gramicidin Channel

E. Bamberg, R. Benz, H. Apell, 1977 .

Separation and characterization of Na+,K(+)-ATPase containing vesicles.

H. Apell, Ivashchuk-Kienbaum YuA, 1994, Biochimica et biophysica acta.

Optical study of active ion transport in lipid vesicles containing reconstituted Na,K-ATPase

M. M. Marcus, H. Apell, H. Oetliker, 2005, The Journal of Membrane Biology.

The KdpFABC complex – K+ transport against all odds

D. Stokes, H. Apell, B. P. Pedersen, 2019, Molecular membrane biology.

Quantitative analysis of pump-mediated fluxes in reconstituted lipid vesicles

H. Apell, P. Läuger, 1986 .

Time-resolved fluorescence investigations of the interaction of the voltage-sensitive probe RH421 with lipid membranes and proteins.

J. Frank, A. Visser, H. Apell, 1995, Biochemistry.

FXYD Proteins Stabilize Na,K-ATPase

Y. Peleg, N. Mishra, D. Voelker, 2011, The Journal of Biological Chemistry.

Characterization of the macrocyclic carbon suboxide factors as potent Na,K-ATPase and SR Ca-ATPase inhibitors.

H. Apell, L. Moroder, R. Stimac, 2002, Biochimica et biophysica acta.

Binding of sodium ions and cardiotonic steroids to native and selectively trypsinized Na,K pump, detected by charge movements.

B. Schwappach, H. Apell, S. Karlish, 1994, The Journal of biological chemistry.

Function and Molecular Aspects of Biomembrane Transport Effects of Electrical Charges on the Permeability of the Gramici- Din Channel

E. Bamberg, H. Apell, H. Alpes, 2022 .

Surface Charges of the Membrane Crucially Affect Regulation of Na,K-ATPase by Phospholemman (FXYD1)

A. Katz, H. Apell, Erica Cirri, 2013, The Journal of Membrane Biology.

Gramicidin channel controversy — the structure in a lipid environment

F. J. Sigworth, O. S. Andersen, E. Bamberg, 1999, Nature Structural Biology.

Kinetics of the Ca(2+), H(+), and Mg(2+) interaction with the ion-binding sites of the SR Ca-ATPase.

C. Peinelt, H. Apell, 2002, Biophysical journal.

Study of Ion Pump Activity Using Black Lipid Membranes

H. Apell, V. Sokolov, 2015 .

Properties of the Cytoplasmic Ion Binding Sites a

H. Apell, Annemarie Schneeberger, W. Domaszewicz, 1997, Annals of the New York Academy of Sciences.

Electrostatic Stabilization Plays a Central Role in Autoinhibitory Regulation of the Na+,K+-ATPase.

H. Khandelia, H. Apell, F. Cornelius, 2017, Biophysical journal.

Rate limitation of the Na(+),K(+)-ATPase pump cycle.

H. Apell, F. Cornelius, E. Grell, 2001, Biophysical journal.

Modulation of the Na,K-ATPase by Magnesium Ions.

H. Apell, T. Hitzler, Grischa Schreiber, 2017, Biochemistry.

Binding of Potassium Ions Inside the Access Channel at the Cytoplasmic Side of Na+,K+-ATPase

V. Y. Tashkin, H. Apell, V. Sokolov, 2018, Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology.