P. Scott

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Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology

R. Kumar, S. Sundar, A. Haque, 2016, PLoS pathogens.

Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens

R. Coffman, A. Sher, E. Pearce, 1988, The Journal of experimental medicine.

Granzyme B Produced by Natural Killer Cells Enhances Inflammatory Response and Contributes to the Immunopathology of Cutaneous Leishmaniasis.

P. Scott, C. Brodskyn, L. Carvalho, 2019, The Journal of infectious diseases.

The role of interleukin 12 in the immune response, disease and therapy.

G. Trinchieri, P. Scott, 1994, Immunology today.

Interleukin-12: basic principles and clinical applications.

G. Trinchieri, P. Scott, 1999, Current topics in microbiology and immunology.

Functional Dichotomy of Dendritic Cells following Interaction with Leishmania braziliensis: Infected Cells Produce High Levels of TNF-α, whereas Bystander Dendritic Cells Are Activated to Promote T Cell Responses1

E. Pearce, P. Scott, L. Carvalho, 2008, The Journal of Immunology.

Intermediate monocytes contribute to pathologic immune response in Leishmania braziliensis infections.

D. Beiting, P. Scott, D. Mosser, 2015, The Journal of infectious diseases.

Vaccination against cutaneous leishmaniasis in a murine model. I. Induction of protective immunity with a soluble extract of promastigotes.

A. Sher, E. Pearce, P. Scott, 1987, Journal of Immunology.

Dendritic cells and immunity to leishmaniasis and toxoplasmosis.

C. Hunter, P. Scott, 2002, Current opinion in immunology.

The Leishmania mexicana Cysteine Protease, CPB2.8, Induces Potent Th2 Responses 1

R. Lyons, G. H. Coombs, J. Mottram, 2003, The Journal of Immunology.

Microbiota instruct IL-17A-producing innate lymphoid cells to promote skin inflammation in cutaneous leishmaniasis

A. M. Carvalho, E. Grice, P. Scott, 2021, bioRxiv.

Microbiota instruct IL-17A-producing innate lymphoid cells to promote skin inflammation in cutaneous leishmaniasis

E. Grice, P. Scott, T. P. Singh, 2021, PLoS pathogens.

The role of IL‐27 in the development of T‐cell responses during parasitic infections

C. Hunter, D. Artis, P. Scott, 2004, Immunological reviews.

IFN-gamma modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis.

P. Scott, 1991, Journal of immunology.

Intradermal Synthetic DNA Vaccination Generates Leishmania-Specific T Cells in the Skin and Protection against Leishmania major

D. Weiner, P. Scott, K. Broderick, 2019, Infection and Immunity.

The role of T-cell subsets and cytokines in the regulation of infection.

S. Kaufmann, P. Scott, Phillip Scott, 1991, Immunology today.

The IL-27 Receptor (WSX-1) Is an Inhibitor of Innate and Adaptive Elements of Type 2 Immunity1

G. Wu, C. Hunter, F. D. de Sauvage, 2004, The Journal of Immunology.

TRAF 6 Is a Critical Factor for Dendritic Cell Maturation and Development on high surface expression of CD 11 c and differential expression of the conventional T cell markers CD 4 and CD

C. Hunter, J. Caamaño, L. Turka, 2003 .

Differential requirement of CD28 for IL‐12 receptor expression and function in CD4+ and CD8+ T cells

P. Scott, M. Elloso, 2001, European journal of immunology.

Protection against Leishmania major in BALB/c mice by adoptive transfer of a T cell clone recognizing a low molecular weight antigen released by promastigotes.

A. Sher, P. Scott, P. Caspar, 1990, Journal of immunology.

Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice

P. Scott, T. Scharton, 1993, The Journal of experimental medicine.

The role of natural killer cells in host-parasite interactions.

G. Trinchieri, P. Scott, Giorgio Trinchieri, 1995, Current opinion in immunology.

Variable gene expression and parasite load predict treatment outcome in cutaneous leishmaniasis

C. Amorim, D. Beiting, P. Scott, 2019, Science Translational Medicine.

The role of IL‐12 in the maintenance of an established Th1 immune response in experimental leishmaniasis

G. Trinchieri, P. Scott, M. Wysocka, 1998, European journal of immunology.

Maintenance of IL‐12‐responsive CD4+ T cells during a Th2 response in Leishmania major‐infected mice

P. Scott, B. Hondowicz, M. Merle Elloso, 2000, European journal of immunology.

IL-4- and IL-5-dependent protective immunity to Onchocerca volvulus infective larvae in BALB/cBYJ mice.

P. Scott, D. Abraham, A. Lange, 1994, Journal of immunology.

TNF receptor p55 is required for elimination of inflammatory cells following control of intracellular pathogens.

M. Nashleanas, P. Scott, S. Kanaly, 1999, Journal of immunology.

Differentiation, regulation, and death of T helper cell subsets during infection with leishmania major

P. Scott, 1998, Immunologic research.

Control of Leishmania major infection in mice lacking TNF receptors.

M. Nashleanas, P. Scott, S. Kanaly, 1998, Journal of immunology.

Engagement of NKG2D on Bystander Memory CD8 T Cells Promotes Increased Immunopathology following Leishmania major Infection

E. Wherry, P. Scott, M. Goldschmidt, 2014, PLoS pathogens.

Immunologic memory in cutaneous leishmaniasis

P. Scott, 2005, Cellular microbiology.

The development of effector and memory T cells in cutaneous leishmaniasis: the implications for vaccine development

D. Artis, P. Scott, C. Zaph, 2004, Immunological reviews.

Inducing a Strong Th1 Response Mice from Virulent Challenge without Protects Highly Susceptible Leishmania major Vaccination with Phosphoglycan-Deficient

P. Scott, S. Beverley, G. Späth, 2004 .

Central memory T cells mediate long-term immunity to Leishmania major in the absence of persistent parasites

P. Scott, S. Beverley, C. Zaph, 2004, Nature Medicine.

Vaccination with Phosphoglycan-Deficient Leishmania major Protects Highly Susceptible Mice from Virulent Challenge without Inducing a Strong Th1 Response1

P. Scott, S. Beverley, G. Späth, 2004, The Journal of Immunology.

Memory T cells in cutaneous leishmaniasis.

P. Scott, Nelson D. Glennie, 2016, Cellular immunology.

IFN- Infection Requires IL-12 to Produce major Leishmania Population Generated during T Cell + The Central Memory CD4

P. Scott, N. Pakpour, C. Zaph, 2014 .

IFN-Infection Requires IL-12 to Produce Population Generated during Leishmania The Central Memory CD4+ T Cell

P. Scott, N. Pakpour, C. Zaph, 2013 .

The Central Memory CD4+ T Cell Population Generated during Leishmania major Infection Requires IL-12 to Produce IFN-γ1

P. Scott, N. Pakpour, C. Zaph, 2008, The Journal of Immunology.

Persistence and Function of Central and Effector Memory CD4+ T Cells following Infection with a Gastrointestinal Helminth1

D. Artis, P. Scott, M. Goldschmidt, 2006, The Journal of Immunology.

Infection with a Gastrointestinal Helminth T Cells following + Effector Memory CD4 Persistence and Function of Central and

D. Artis, P. Scott, C. Zaph, 2006 .

Long-Lived Skin-Resident Memory T Cells Contribute to Concomitant Immunity in Cutaneous Leishmaniasis.

P. Scott, 2020, Cold Spring Harbor perspectives in biology.

CD8+ T Cells Lack Local Signals To Produce IFN-γ in the Skin during Leishmania Infection

D. Beiting, P. Scott, Fernanda O. Novais, 2018, The Journal of Immunology.

Differential Requirement for NF-κB Family Members in Control of Helminth Infection and Intestinal Inflammation1

C. Hunter, J. Caamaño, S. Shapira, 2002, The Journal of Immunology.

STAT1 Expression in Dendritic Cells, but Not T Cells, Is Required for Immunity to Leishmania major1

P. Scott, Leanne M. Johnson, 2007, The Journal of Immunology.

Leishmania major T Cells, Is Required for Immunity to STAT1 Expression in Dendritic Cells, but Not

P. Scott, 2007 .

Fas-Fas Ligand Interactions Are Essential for the Binding to and Killing of Activated Macrophages by γδ T Cells

Jane E. Dalton, P. Scott, S. Carding, 2004, The Journal of Immunology.

Matrix Metalloproteinase 9 Production by Monocytes is Enhanced by TNF and Participates in the Pathology of Human Cutaneous Leishmaniasis

Adriano Queiroz, D. Beiting, P. Scott, 2014, PLoS neglected tropical diseases.

Expression and contribution of B7-1 (CD80) and B7-2 (CD86) in the early immune response to Leishmania major infection.

P. Scott, M. Elloso, 1999, Journal of immunology.

The Early Generation of a Heterogeneous CD4+ T Cell Response to Leishmania major

P. Scott, Sara L. Colpitts, 2010, The Journal of Immunology.

Infection Leishmania major Effector Cells during Central Memory T Cells and Th 1 highCD 62 L Potential for Long-Term Survival of Both IL-7 Receptor Expression Provides the

P. Scott, Sara L. Colpitts, Nicole M. Dalton, 2009 .

Interleukin 17 production among patients with American cutaneous leishmaniasis.

P. Scott, E. Carvalho, K. Gollob, 2009, The Journal of infectious diseases.

IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis.

G. Trinchieri, P. Scott, M. Wysocka, 1995, Journal of immunology.

FIZZ 2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract

M. Lazar, G. Wu, M. Wang, 2004 .

Interleukin 5 is required for the blood and tissue eosinophilia but not granuloma formation induced by infection with Schistosoma mansoni.

R. Coffman, A. Sher, P. Scott, 1990, Proceedings of the National Academy of Sciences of the United States of America.

TH1 and TH2 cell antigen receptors in experimental leishmaniasis.

R. Locksley, Z. E. Wang, F. Hatam, 1993, Science.

Leishmania major-infected C3H mice treated with anti-IL-12 mAb develop but do not maintain a Th2 response.

P. Scott, D. Jones, T. Scharton‐Kersten, 1997, Journal of immunology.

Cutting Edge: NF-κB2 Is a Negative Regulator of Dendritic Cell Function1

C. Hunter, J. Caamaño, P. Scott, 2004, The Journal of Immunology.

Cutting edge: NF-kappa B2 is a negative regulator of dendritic cell function.

C. Hunter, J. Caamaño, P. Scott, 2004, Journal of immunology.

Selective differentiation of CD4+ T helper cell subsets.

P. Scott, 1993, Current opinion in immunology.

Role of Cytokines and CD4+ T‐Cell Subsets in the Regulation of Parasite Immunity and Disease

R. Coffman, A. Sher, P. Scott, 1989, Immunological reviews.

The Interaction of γδ T Cells with Activated Macrophages Is a Property of the Vγ1 Subset 1

Jane E. Dalton, P. Scott, S. Carding, 2003, The Journal of Immunology.

T-cell and cytokine responses in leishmaniasis.

S. Reed, P. Scott, 1993, Current opinion in immunology.

Interaction between the Innate and the Acquired Immune System following Infection of Different Mouse Strains with Leishmania major a

P. Scott, T. Scharton, 1994, Annals of the New York Academy of Sciences.

Efficacy of commercial and field-strain Mycobacterium paratuberculosis vaccinations with recombinant IL-12 in a bovine experimental infection model.

P. Chilton, P. Scott, R. Sweeney, 2003, Vaccine.

Role of Cytokines in the Differentiation of CD4+ T‐Cell Subsets in vivo

R. Coffman, P. Scott, R. Chatelain, 1991, Immunological reviews.

Granzyme B inhibition by tofacitinib blocks pathology induced by CD8 T cells in cutaneous leishmaniasis.

P. Scott, Fernanda O. Novais, B. T. Nguyen, 2020, The Journal of investigative dermatology.

Memory T-cell subsets in parasitic infections.

P. Scott, Sara L. Colpitts, 2010, Advances in experimental medicine and biology.

Adaptive Immune Effector Mechanisms against Intracellular Protozoa and Gut-Dwelling Nematodes

R. Grencis, P. Scott, 2002 .

CD8+ T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1β production

A. M. Carvalho, I. Brodsky, D. Beiting, 2017, PLoS pathogens.

Immunology of Leishmaniasis

P. Scott, Fernanda O. Novais, F. Novais, 2016 .

Leishmania mexicana Induces Limited Recruitment and Activation of Monocytes and Monocyte-Derived Dendritic Cells Early during Infection

P. Scott, D. Manzoni-de-Almeida, Ciara Gimblet, 2012, PLoS neglected tropical diseases.

Beryllium, an Adjuvant That Promotes Gamma Interferon Production

P. Scott, O. Atochina, M. Rossman, 2000, Infection and Immunity.

Regulation of the production of soluble IL‐4 receptors in murine cutaneous leishmaniasis. The roles of IL‐12 and IL‐4

R. Fernandez-Botran, P. Chilton, P. Scott, 1999, Journal of leukocyte biology.

The role of the innate immune response in Th1 cell development following Leishmania major infection

P. Scott, T. Scharton‐Kersten, 1995, Journal of leukocyte biology.

Interleukin 10- and Fcγ Receptor-Deficient Mice Resolve Leishmania mexicana Lesions

P. Scott, L. Buxbaum, 2005, Infection and Immunity.

Differential Regulation of the Interleukin-12 Receptor during the Innate Immune Response to Leishmania major

Douglas E. Jones, G. Trinchieri, L. Showe, 1998, Infection and Immunity.

Immunologic response and memory T cells in subjects cured of tegumentary leishmaniasis

A. M. Carvalho, P. Scott, L. Carvalho, 2013, BMC Infectious Diseases.

Development and regulation of cell-mediated immunity in experimental Leishmaniasis

P. Scott, 2003, Immunologic research.

The Role of IL-12 in Maintaining Resistance to Leishmania major1

P. Scott, M. Kopf, B. Hondowicz, 2002, The Journal of Immunology.

This information is current as Leishmania major to The Role of IL-12 in Maintaining Resistance

P. Scott, M. Kopf, B. Hondowicz, 2002 .

Immunoparasitology

P. Scott, 2004, Immunological reviews.

MHC Class II Expression Restricted to CD8α+ and CD11b+ Dendritic Cells Is Sufficient for Control of Leishmania major

P. Scott, T. Laufer, M. Lemos, 2004, The Journal of experimental medicine.

Genomic profiling of human Leishmania braziliensis lesions identifies transcriptional modules associated with cutaneous immunopathology

D. Roos, D. Beiting, P. Scott, 2014, The Journal of investigative dermatology.

Acquired Immunity to Intracellular Protozoa

E. Riley, P. Scott, 2011 .

Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function

R. Locksley, P. Scott, 1991 .

Drug Discovery for Kinetoplastid Diseases: Future Directions.

G. Dranoff, M. Barrett, J. Mottram, 2018, ACS infectious diseases.

Natural Killer Cells Are a Source o f Interferon 3 ' That Drives Differentiation o f CD 4 + T Cell Subsets and Induces Early Resistance to Leishmania major in Mice By

P. Scott, T. Scharton, 2003 .

IL-17 Mediates Immunopathology in the Absence of IL-10 Following Leishmania major Infection

P. Scott, L. Carvalho, E. Carvalho, 2013, PLoS pathogens.

Low Dose Leishmania major Promotes a Transient T Helper Cell Type 2 Response That Is Down-regulated by Interferon γ–producing CD8+ T Cells

P. Scott, J. Uzonna, K. Joyce, 2004, The Journal of experimental medicine.

Tissue predilection sites and effect of dose on Mycobacterium avium subs. paratuberculosis organism recovery in a short-term bovine experimental oral infection model.

P. Chilton, P. Scott, R. Sweeney, 2006, Research in veterinary science.

Interferon-gamma and interleukin 4 gene expression in cows infected with Mycobacterium paratuberculosis.

P. Scott, R. Sweeney, D. Jones, 1998, American journal of veterinary research.

Phenotypic and functional characteristics of HLA‐DR+ neutrophils in Brazilians with cutaneous leishmaniasis

S. Sundar, Smriti Sharma, P. Scott, 2017, Journal of leukocyte biology.

The respiratory burst is not required for killing of intracellular and extracellular parasites by a lymphokine‐activated macrophage cell line

A. Sher, P. Scott, S. James, 1985, European journal of immunology.

Correlation of Natural Killer Cell Activation, CD4+ TH1 Cell Development and resistance in Experimental Cutaneous Leishmaniasis

P. Scott, T. Scharton, 1993 .

Early Enhanced Th1 Response after Leishmania amazonensis Infection of C57BL/6 Interleukin-10-Deficient Mice Does Not Lead to Resolution of Infection

Douglas E. Jones, C. Hunter, P. Scott, 2002, Infection and Immunity.

Not Lead to Resolution of Infection C 57 BL / 6 Interleukin-10-Deficient Mice Does Infection of Leishmania amazonensis Early Enhanced Th 1 Response after

Douglas E. Jones, C. Hunter, P. Scott, 2002 .

IL-4-Independent Inhibition of IL-12 Responsiveness During Leishmania amazonensis Infection1

Douglas E. Jones, P. Scott, L. Buxbaum, 2000, The Journal of Immunology.

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions.

G. Trinchieri, P. Scott, 1995, Research in immunology.

Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function.

R. Locksley, P. Scott, 1991, Immunology today.

Mice lacking the TNF receptor p55 fail to resolve lesions caused by infection with Leishmania major, but control parasite replication.

K. Pfeffer, M. Nashleanas, P. Scott, 1996, Journal of immunology.

Skin-resident CD4+ T cells protect against Leishmania major by recruiting and activating inflammatory monocytes

P. Scott, S. Volk, Nelson D. Glennie, 2017, PLoS pathogens.

CD8+ T cells in cutaneous leishmaniasis: the good, the bad, and the ugly

P. Scott, Fernanda O. Novais, F. Novais, 2015, Seminars in Immunopathology.

CD 8 + T cells in cutaneous leishmaniasis : The good , the bad and the ugly

P. Scott, Fernanda O. Novais, F. Novais, 2015 .

Finding Leishmania: a deadly game of hide-and-seek.

P. Scott, 2009, Cell host & microbe.

Activated T Cells Induce Macrophages To Produce NO and Control Leishmania major in the Absence of Tumor Necrosis Factor Receptor p55

M. Nashleanas, P. Scott, 2000, Infection and Immunity.

Influence of Parasite Load on the Ability of Type 1 T Cells To Control Leishmania major Infection

P. Scott, B. Hondowicz, 2002, Infection and Immunity.

The role of IL12 in modulating an established Th2 response in experimental leishmaniasis.

P. Scott, B. Hondowicz, 1995, Research in immunology.

Host and parasite factors regulating the development of CD4+ T-cell subsets in experimental cutaneous leishmaniasis.

P. Scott, 1991, Research in immunology.

Immune responses associated with susceptibility of C57BL/10 mice to Leishmania amazonensis

P. Scott, L. C. Afonso, 1993, Infection and immunity.

Early Cutaneous Leishmaniasis Patients Infected With Leishmania braziliensis Express Increased Inflammatory Responses After Antimony Therapy

P. Scott, L. Carvalho, P. Machado, 2018, The Journal of infectious diseases.

In vivo alterations in cytokine production following interleukin-12 (IL-12) and anti-IL-4 antibody treatment of CB6F1 mice with chronic cutaneous leishmaniasis

P. Scott, J. Farrell, J. Li, 1996, Infection and immunity.

Cysteine Protease B of Leishmania mexicana Inhibits Host Th1 Responses and Protective Immunity 1

G. H. Coombs, J. Mottram, P. Scott, 2003, The Journal of Immunology.

Immunity Inhibits Host Th1 Responses and Protective Leishmania mexicana Cysteine Protease B of

G. H. Coombs, J. Mottram, P. Scott, 2003 .

Control of New World cutaneous leishmaniasis is IL‐12 independent but STAT4 dependent

P. Scott, M. Goldschmidt, J. Uzonna, 2002, European journal of immunology.

IL‐12: Keeping Cell‐Mediated Immunity Alive

P. Scott, A. Y. Park, 2001, Scandinavian journal of immunology.

Vervet Monkeys Vaccinated with Killed Leishmania major Parasites and Interleukin-12 Develop a Type 1 Immune Response but Are Not Protected against Challenge Infection

F. Modabber, P. Scott, J. Olobo, 2001, Infection and Immunity.

Infection Leishmania major Response During IL-12 Is Required to Maintain a Th1

P. Scott, B. Hondowicz, A. Y. Park, 2000 .

Influence of host and parasite factors on the innate immune response and Th2 stability following infection with Leishmania major.

P. Scott, B. Hondowicz, 1999, Microbes and infection.

Leishmania major to Receptor during the Innate Immune Response Differential Regulation of the Interleukin-12

Douglas E. Jones, G. Trinchieri, L. Showe, 1998 .

IL‐12 eliminates the Th‐2 dependent protective immune response of mice to larval Strongyloides stercoralis

H. Rotman, T. Nolan, P. Scott, 1997, Parasite immunology.

Leishmania major Metacyclogenesis Modulates Ability to Induce IL‐12

G. Trinchieri, P. Scott, A. Sartori, 1996, Annals of the New York Academy of Sciences.

The Role of IL‐12 in Regulation of T Helper Cell Subsets in Vivo

P. Scott, T. Scharton‐Kersten, B. Hondowicz, 1996, Annals of the New York Academy of Sciences.

Infection with Leishmania major induces interleukin-12 production in vivo.

G. Trinchieri, P. Scott, L. Afonso, 1994, Immunology letters.

Host susceptibility factors to cutaneous leishmaniasis.

Douglas E. Jones, P. Scott, D. Jones, 1998, Frontiers in bioscience : a journal and virtual library.

[Frontiers in Bioscience 3, d1171-1180, November 15, 1998] 1171 HOST SUSCEPTIBILITY FACTORS TO CUTANEOUS LEISHMANIASIS

Douglas E. Jones, P. Scott, M. Elloso, 1998 .

Cell Responses Dendritic Cells Are Activated to Promote T , whereas Bystander a Levels of TNF-: Infected Cells Produce High braziliensis Leishmania following Interaction with Functional Dichotomy of Dendritic Cells

E. Pearce, P. Scott, L. Carvalho, 2008 .

IL-31–IL-31R interactions negatively regulate type 2 inflammation in the lung

E. Pearce, F. D. de Sauvage, J. Perrigoue, 2007, The Journal of experimental medicine.

Cutaneous leishmaniasis in anti-IgM-treated mice: enhanced resistance due to functional depletion of a B cell-dependent T cell involved in the suppressor pathway.

P. Scott, F. Sher, D. Sacks, 1984, Journal of immunology.

A spectrum in the susceptibility of leishmanial strains to intracellular killing by murine macrophages.

A. Sher, P. Scott, 1986, Journal of immunology.

Protective and Pathological Functions of CD8+ T Cells in Leishmania braziliensis Infection

Adriano Queiroz, P. Scott, L. Carvalho, 2014, Infection and Immunity.

Combined Treatment with Interleukin-12 and Indomethacin Promotes Increased Resistance in BALB/c Mice with Established Leishmania major Infections

P. Scott, Jian Li, J. Farrell, 2002, Infection and Immunity.

Lacking TNF Receptors Infection in Mice Leishmania major Control of

M. Nashleanas, P. Scott, S. Kanaly, 1998 .

T-cell subsets and T-cell antigens in protective immunity against experimental leishmaniasis.

P. Scott, 1990, Current topics in microbiology and immunology.

Immunity to protozoa.

P. Scott, L. Miller, 1990, Current opinion in immunology.

The role of TH1 and TH2 cells in experimental cutaneous leishmaniasis.

P. Scott, 1989, Experimental parasitology.

Induction of cell-mediated immunity as a strategy for vaccination against parasites.

A. Sher, P. Scott, P. T. Englund, 1988 .

Glyburide, a NLRP3 inhibitor, decreases inflammatory response and is a candidate to reduce pathology in Leishmania braziliensis infection.

A. M. Carvalho, P. Scott, L. Carvalho, 2020, The Journal of investigative dermatology.

Interleukin-12 Regulates Chemokine Gene Expression during the Early Immune Response to Leishmania major

P. Scott, C. Zaph, 2003, Infection and Immunity.

Leishmania major Response to Expression during the Early Immune Interleukin-12 Regulates Chemokine Gene

P. Scott, C. Zaph, 2003 .

Experimental cutaneous leishmaniasis. I. Nonspecific immunodepression in BALB/c mice infected with Leishmania tropica.

P. Scott, J. Farrell, 1981, Journal of immunology.

Impaired macrophage leishmanicidal activity at cutaneous temperature

P. Scott, 1985, Parasite immunology.

Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin 12 and Pentostam.

P. Scott, G S Nabors, L C Afonso, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Germ-free mice produce high levels of interferon-gamma in response to infection with Leishmania major but fail to heal lesions

J. Nicoli, P. Scott, E. Vieira, 2005, Parasitology.

Skin-resident memory CD4+ T cells enhance protection against Leishmania major infection

C. Weaver, D. Beiting, P. Scott, 2015, The Journal of experimental medicine.

IL-22 Protects against Tissue Damage during Cutaneous Leishmaniasis

E. Grice, D. Artis, P. Scott, 2015, PloS one.

B lymphocytes are required for the generation of T cells that mediate healing of cutaneous leishmaniasis.

A. Sher, P. Scott, P. Natovitz, 1986, Journal of immunology.

Host and parasite factors influencing the expression of cutaneous leishmaniasis.

A. Sher, P. Scott, D. Sacks, 1983, Ciba Foundation symposium.

The skin microbiome enhances disease through IL-1Î² and delays healing in cutaneous leishmaniasis patients

E. Grice, D. Beiting, C. Farias Amorim, 2023, medRxiv.

The adjuvant effect of interleukin-12 in a vaccine against Leishmania major

G. Trinchieri, P. Scott, M. Wysocka, 1994 .

Leishmaniasis: complexity at the host–pathogen interface

P. Kaye, P. Scott, 2011, Nature Reviews Microbiology.

Effect of chronic ethanol consumption on protective T-helper 1 and T-helper 2 immune responses against the parasites Leishmania major and Strongyloides stercoralis in mice.

T. Nolan, P. Scott, A. Krolewiecki, 2001, Alcoholism, clinical and experimental research.

Vaccination against cutaneous leishmaniasis in a murine model. II. Immunologic properties of protective and nonprotective subfractions of soluble promastigote extract.

A. Sher, E. Pearce, P. Scott, 1987, Journal of immunology.

Cutaneous leishmaniasis: immune responses in protection and pathogenesis

P. Scott, Fernanda O. Novais, Phillip Scott, 2016, Nature Reviews Immunology.

Cutaneous leishmaniasis — which is caused by several protozoal parasites of the genus Leishmania — is endemic to South and Central America, Northern Africa, the Middle East and parts of Asia, and an estimated 1 mil‐

P. Scott, F. Novais, 2016 .

IL-12: initiation cytokine for cell-mediated immunity.

P. Scott, 1993, Science.

Host-Directed Therapies for Cutaneous Leishmaniasis

C. Amorim, P. Scott, F. Novais, 2021, Frontiers in Immunology.

Leishmania braziliensis Infection Enhances Toll-Like Receptors 2 and 4 Expression and Triggers TNF-α and IL-10 Production in Human Cutaneous Leishmaniasis

P. Scott, P. Machado, E. Carvalho, 2019, Front. Cell. Infect. Microbiol..

Cytotoxic T Cells Mediate Pathology and Metastasis in Cutaneous Leishmaniasis

D. Roos, G. Ruthel, M. Betts, 2013, PLoS pathogens.

Modulation of susceptibility and resistance to an autoimmune model of multiple sclerosis in prototypically susceptible and resistant strains by neutralization of interleukin-12 and interleukin-4, respectively.

G. Trinchieri, L. Showe, P. Scott, 2001, Clinical immunology.

Cutting Edge: A Critical Role for Gene Silencing in Preventing Excessive Type 1 Immunity1

A. Bird, D. Artis, P. Scott, 2005, Journal of Immunology.

NF-κB1 Is Required for Optimal CD4+ Th1 Cell Development and Resistance to Leishmania major 1

C. Hunter, J. Caamaño, D. Artis, 2003, The Journal of Immunology.

NF-κB2 Is Required for Optimal CD40-Induced IL-12 Production but Dispensable for Th1 Cell Differentiation1

C. Hunter, J. Caamaño, P. Scott, 2002, The Journal of Immunology.

Dispensable for Th 1 Cell Differentiation CD 40-Induced IL-12 Production but B 2 Is Required for Optimal κ NF -

C. Hunter, J. Caamaño, P. Scott, 2002 .

Leishmania mexicana Infection Induces Impaired Lymph Node Expansion and Th1 Cell Differentiation Despite Normal T Cell Proliferation1

P. Scott, Alice C. Hsu, 2007, The Journal of Immunology.

Dendritic Cell-Intrinsic Expression of NF-κB1 Is Required to Promote Optimal Th2 Cell Differentiation1

C. Hunter, E. Pearce, S. Shapira, 2005, The Journal of Immunology.

Migratory Dermal Dendritic Cells Act as Rapid Sensors of Protozoan Parasites

L. Ng, P. Scott, W. Weninger, 2008, PLoS pathogens.

RELMbeta/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract.

M. Lazar, M. Wang, S. Keilbaugh, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Mammalian Casein Kinase 1α and Its Leishmanial Ortholog Regulate Stability of IFNAR1 and Type I Interferon Signaling

K. Mclaughlin, D. Baker, M. Weiss, 2009, Molecular and Cellular Biology.

Selective whole-genome amplification reveals population genetics of Leishmania braziliensis directly from patient skin biopsies

Yun S. Song, Jane A. Yu, Alexander S. F. Berry, 2022, medRxiv.

Human classical monocytes control the intracellular stage of Leishmania braziliensis by reactive oxygen species.

D. Beiting, P. Scott, L. Carvalho, 2014, The Journal of infectious diseases.

Leishmania Infection Induces Macrophage Vascular Endothelial Growth Factor A Production in an ARNT/HIF-Dependent Manner

P. Scott, A. Bowlin, Tiffany Weinkopff, 2019, Infection and Immunity.

Leishmania major Infection–Induced VEGF-A/VEGFR-2 Signaling Promotes Lymphangiogenesis That Controls Disease

C. Hunter, D. Discher, P. Scott, 2016, The Journal of Immunology.

Th1 Cell-Mediated Resistance to Cutaneous Infection with Leishmania major Is Independent of P- and E-Selectins 1

P. Scott, C. Zaph, 2003, The Journal of Immunology.

Schistosomiasis delays lesion resolution during Leishmania major infection by impairing parasite killing by macrophages

E. Pearce, P. Scott, A. L. La Flamme, 2002, Parasite immunology.

Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion

Laura A. L. Dillon, N. El-Sayed, D. Beiting, 2016, PLoS neglected tropical diseases.

1 Subset g Macrophages Is a Property of the V T Cells with Activated d g The Interaction of

Jane E. Dalton, P. Scott, Jayne Pearson, 2003 .

The adjuvant effect of interleukin-12 in a vaccine against Leishmania major.

G. Trinchieri, P. Scott, M. Wysocka, 1994, Science.

Lymphocytic Choriomeningitis Virus Expands a Population of NKG2D+CD8+ T Cells That Exacerbates Disease in Mice Coinfected with Leishmania major

E. Wherry, P. Scott, M. Clark, 2015, The Journal of Immunology.

Fas-Fas ligand interactions are essential for the binding to and killing of activated macrophages by gamma delta T cells.

Jane E. Dalton, P. Scott, S. Carding, 2004, Journal of immunology.

IL-1β Production by Intermediate Monocytes Is Associated with Immunopathology in Cutaneous Leishmaniasis.

P. Scott, L. Carvalho, P. Machado, 2017, The Journal of investigative dermatology.

TLR9 Infection Is Dependent on Leishmania major Lymph Node Hypertrophy following

D. Artis, P. Scott, L. Carvalho, 2014 .

Lymph Node Hypertrophy following Leishmania major Infection Is Dependent on TLR9

D. Artis, P. Scott, L. Carvalho, 2012, The Journal of Immunology.

Control of Leishmania major by a monoclonal alpha beta T cell repertoire.

C. Turck, R. Locksley, N. Killeen, 1998, Journal of immunology.

Experimental Leishmania major Infection Suppresses HIV-1 DNA Vaccine Induced Cellular Immune Response

D. Artis, P. Scott, J. Boyer, 2004, Cells Tissues Organs.

In Vivo Recognition of Ovalbumin Expressed by Transgenic Leishmania Is Determined by Its Subcellular Localization1

P. Kaye, Deborah F. Smith, P. Scott, 2006, The Journal of Immunology.

Its Subcellular Localization Is Determined by Leishmania by Transgenic In Vivo Recognition of Ovalbumin Expressed

P. Kaye, Deborah F. Smith, P. Scott, 2006 .

CD4+ T cells that evade deletion by a self peptide display Th1‐biased differentiation

P. Scott, M. Jordan, A. Caton, 2001, European journal of immunology.

Early IL-4 production does not predict susceptibility to Leishmania major.

W. Gause, P. Scott, Xia Zhou, 1996, Experimental parasitology.

Antigen-Experienced T Cells Limit the Priming of Naive T Cells during Infection with Leishmania major1

P. Kaye, Deborah F. Smith, P. Scott, 2006, The Journal of Immunology.

IL-12 as an adjuvant for cell-mediated immunity.

G. Trinchieri, P. Scott, Giorgio Trinchieri, 1997, Seminars in immunology.

Faculty Opinions recommendation of Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

P. Scott, 2003 .

IL-7 Receptor Expression Provides the Potential for Long-Term Survival of Both CD62Lhigh Central Memory T Cells and Th1 Effector Cells during Leishmania major Infection1

P. Scott, Phillip Scott, Sara L. Colpitts, 2009, The Journal of Immunology.

Transcriptomic landscape of skin lesions in cutaneous leishmaniasis reveals a strong CD8+ T cell immunosenescence signature linked to immunopathology

C. Amorim, P. Scott, D. Mosser, 2021, Immunology.

Cutaneous Leishmaniasis Induces a Transmissible Dysbiotic Skin Microbiota that Promotes Skin Inflammation.

Charles W. Bradley, Jacquelyn S Meisel, Jacquelyn S. Meisel, 2017, Cell host & microbe.

Activity of azithromycin against Leishmania major in vitro and in vivo.

P. Scott, A. Krolewiecki, D. Abraham, 2002, The American journal of tropical medicine and hygiene.

UNC93B1 and Nucleic Acid-sensing Toll-like Receptors Mediate Host Resistance to Infection with Leishmania major*

D. Golenbock, R. Gazzinelli, P. Scott, 2013, The Journal of Biological Chemistry.

Tissue Damage in Human Cutaneous Leishmaniasis: Correlations Between Inflammatory Cells and Molecule Expression

Lucas de Francisco Carvalho, Adriano Queiroz, P. Scott, 2020, Frontiers in Cellular and Infection Microbiology.

Metacyclogenesis modulates the ability of Leishmania promastigotes to induce IL-12 production in human mononuclear cells.

G. Trinchieri, P. Scott, G Trinchieri, 1997, Journal of immunology.

Characterization of the Histopathologic Features in Patients in the Early and Late Phases of Cutaneous Leishmaniasis

Adriano Queiroz, P. Scott, S. Arruda, 2017, The American journal of tropical medicine and hygiene.

IL-12 Is Required to Maintain a Th1 Response During Leishmania major Infection1

P. Scott, B. Hondowicz, A. Y. Park, 2000, The Journal of Immunology.

The maternal vaginal microbiome partially mediates the effects of prenatal stress on offspring gut and hypothalamus

T. Bale, D. Beiting, P. Scott, 2018, Nature Neuroscience.

Correction: Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion

Laura A. L. Dillon, N. El-Sayed, D. Beiting, 2017, PLoS Neglected Tropical Diseases.

Leishmania major Phosphoglycans Influence the Host Early Immune Response by Modulating Dendritic Cell Functions

P. Scott, N. Pakpour, S. Beverley, 2009, Infection and Immunity.

Localized skin inflammation during cutaneous leishmaniasis drives a chronic, systemic IFN-γ signature

D. Beiting, C. Farias Amorim, P. Scott, 2021, PLoS neglected tropical diseases.

Localized skin inflammation during cutaneous leishmaniasis drives a chronic, systemic IFN-Î³ signature

C. Amorim, D. Beiting, P. Scott, 2020, medRxiv.

TRAF6 is a critical factor for dendritic cell maturation and development.

C. Hunter, J. Caamaño, L. Turka, 2003, Immunity.

Cutting Edge: Early IL-4 Production Governs the Requirement for IL-27-WSX-1 Signaling in the Development of Protective Th1 Cytokine Responses following Leishmania major Infection1

C. Hunter, D. Artis, P. Scott, 2004, The Journal of Immunology.

Inhibition of gamma-secretase activity without interfering in Notch signalling decreases inflammatory response in patients with cutaneous leishmaniasis

A. M. Carvalho, C. Amorim, D. Beiting, 2021, Emerging microbes & infections.

Single gene control of resistance to cutaneous leishmaniasis in mice

P. Scott, L. Detolla, J. Farrell, 2004, Immunogenetics.

Experimental cutaneous leishmaniasis: disseminated leishmaniasis in genetically susceptible and resistant mice.

P. Scott, J. Farrell, 1982, The American journal of tropical medicine and hygiene.

Immunization with Persistent Attenuated Δlpg2 Leishmania major Parasites Requires Adjuvant To Provide Protective Immunity in C57BL/6 Mice

P. Scott, S. Beverley, C. Kébaïer, 2006, Infection and Immunity.

Identification of T-cell-reactive antigens that protect BALB/c mice against Leishmania major.

A. Sher, E. Pearce, P. Scott, 1987, Annales de l'Institut Pasteur. Immunology.

Immunodepression in BALB/c mice infected with Leishmania tropica.

P. Scott, J. Farrell, 1983, Advances in experimental medicine and biology.

CD8+ T cells in cutaneous leishmaniasis: the good, the bad, and the ugly

P. Scott, F. Novais, 2015, Seminars in Immunopathology.

Experimental Approaches to Studying the Immunology of Parasitic Diseases

E. Pearce, P. Scott, 2000 .

Th cell development and regulation in experimental cutaneous leishmaniasis.

P. Scott, 1996, Chemical immunology.

Experimental cutaneous leishmaniasis: induction and regulation of T cells following infection of mice with Leishmania major.

P. Scott, J. Farrell, 1998, Chemical immunology.

Recognition of Leishmania donovani antigens by murine T lymphocyte lines and clones. Species cross-reactivity, functional correlates of cell-mediated immunity, and antigen characterization.

H. Sheppard, P. Scott, D. Dwyer, 1983, Journal of immunology.

The interaction of gamma delta T cells with activated macrophages is a property of the V gamma 1 subset.

Jane E. Dalton, P. Scott, S. Carding, 2003, Journal of Immunology.

CD4+ T cell subsets in experimental cutaneous leishmaniasis.

R. Coffman, A. Sher, E. Pearce, 1988, Memorias do Instituto Oswaldo Cruz.

Resistance to macrophage-mediated killing as a factor influencing the pathogenesis of chronic cutaneous leishmaniasis.

A. Sher, P. Scott, D. Sacks, 1983, Journal of immunology.

Correction: Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion

Laura A. L. Dillon, N. El-Sayed, D. Beiting, 2017, PLoS Neglected Tropical Diseases.

Genetic Factors Influencing the Interaction of Parasites with the Immune System

A. Sher, P. Scott, 1982, Clinics in Immunology and Allergy.

The Role of IL-12 in Maintaining Resistance to Leishmania major1

P. Scott, M. Kopf, B. Hondowicz, 2002, The Journal of Immunology.

This information is current as Leishmania major to The Role of IL-12 in Maintaining Resistance

P. Scott, M. Kopf, B. Hondowicz, 2002 .

NF-kappa B1 is required for optimal CD4+ Th1 cell development and resistance to Leishmania major.

C. Hunter, J. Caamaño, D. Artis, 2003, Journal of immunology.

The maternal vaginal microbiome partially mediates the effects of prenatal stress on offspring gut and hypothalamus

T. Bale, D. Beiting, P. Scott, 2018, Nature Neuroscience.

NKG2D promotes CD8 T cell-mediated cytotoxicity and is associated with treatment failure in human cutaneous leishmaniasis

D. Beiting, C. Farias Amorim, P. Scott, 2023, PLoS neglected tropical diseases.