K. Miyake

K. Miyake, S. Akashi-Takamura, Sachiko Akashi-Takamura, 2006, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Two waves of memory B-cell generation in the primary immune response.

T. Tokuhisa, R. Abe, K. Miyake, 2005, International immunology.

Phospholipase A2 from Bee Venom Increases Poly(I:C)-induced Activation in Human Keratinocytes.

Yasuhiko Ito, K. Miyake, Susumu Tomono, 2020, International immunology.

Controlling systems of nucleic acid sensing-TLRs restrict homeostatic inflammation.

K. Miyake, Ryutaro Fukui, 2012, Experimental cell research.

Monoclonal antibodies to CD44 and their influence on hyaluronan recognition

Q. He, K. Miyake, R. Parkhouse, 1995, The Journal of cell biology.

Mechanism of Anticancer Host Response Induced by OK-432, a Streptococcal Preparation, Mediated by Phagocytosis and Toll-Like Receptor 4 Signaling

K. Miyake, S. Akashi, S. Ahmed, 2006, Journal of immunotherapy.

Lipopolysaccharide Hyporesponsiveness Leading to Porphyromonas gingivalis Cysteine Proteinases ( Gingipains ) from Proteolysis of Human Monocyte CD 14 by Miyake

E. Nemoto, K. Miyake, H. Tada, 2000 .

Recognition of murine integrin beta 1 by a rat anti-stromal cell monoclonal antibody.

J. Gimble, K. Miyake, X. Wu, 1994, Hybridoma.

Role of the Orphan Transporter SLC35E1 in the Nuclear Egress of Herpes Simplex Virus 1

M. Oyama, S. Miyano, S. Imoto, 2022, Journal of virology.

Emerging roles of basophils in allergic inflammation.

H. Karasuyama, K. Miyake, 2017, Allergology international : official journal of the Japanese Society of Allergology.

A Notch Ligand, Delta-Like 1 Functions As an Adhesion Molecule for Mast Cells

S. Niida, K. Okuyama, K. Miyake, 2010, The Journal of Immunology.

Auranofin, as an anti-rheumatic gold compound, suppresses LPS-induced homodimerization of TLR4.

K. Miyake, S. Saitoh, H. Youn, 2006, Biochemical and biophysical research communications.

CT-M8 Mice: A New Mouse Model Demonstrates That Basophils Have a Nonredundant Role in Lupus-Like Disease Development

Christophe Pellefigues, E. Daugas, H. Karasuyama, 2022, Frontiers in Immunology.

Activation-induced expression of thymic shared antigen-1 on T lymphocytes and its inhibitory role for TCR-mediated IL-2 production.

K. Miyake, T. Hamaoka, S. Saitoh, 1994, International immunology.

Involvement of Toll-like receptor 4 signaling in interferon-gamma production and antitumor effect by streptococcal agent OK-432.

S. Akira, O. Takeuchi, K. Miyake, 2003, Journal of the National Cancer Institute.

Highly restricted expression of a stromal cell determinant in mouse bone marrow in vivo

K. Miyake, D. G. Osmond, P. Kincade, 1992, The Journal of experimental medicine.

Eritoran inhibits S100A8-mediated TLR4/MD-2 activation and tumor growth by changing the immune microenvironment

A. Kitao, K. Takemura, K. Miyake, 2016, Oncogene.

Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: a molecular basis for priming and synergism with bacterial lipopolysaccharide.

A. Mantovani, S. Bernasconi, K. Miyake, 2002, Blood.

Cloning of murine and rat vascular cell adhesion molecule-1.

L. Burkly, K. Miyake, P. Moy, 1992, Biochemical and biophysical research communications.

Differentiation stages of eosinophils characterized by hyaluronic acid binding via CD44 and responsiveness to stimuli.

A. Tominaga, K. Miyake, Y. Watanabe, 2001, DNA and cell biology.

Toll-like receptors in COPD

K. Miyake, P. Hansbro, M. Starkey, 2017, European Respiratory Journal.

ADP-ribosylation factor-like 8b is required for the development of mouse models of systemic lupus erythematosus

Katsuaki Sato, K. Miyake, S. Saitoh, 2019, International immunology.

Genetic dissection of TLR9 reveals complex regulatory and cryptic proinflammatory roles in mouse lupus

M. Shlomchik, S. Smita, S. Bastacky, 2022, Nature Immunology.

Analysis of Vβ4 T cell receptor CDR3 repertoire in BALB/c and (NZB×NZW)F1 mice

M. Tokushima, K. Miyake, M. Kimoto, 1997 .

Cholera toxin B induces interleukin-1β production from resident peritoneal macrophages through the pyrin inflammasome as well as the NLRP3 inflammasome

K. Ishii, Takako Yamaguchi, T. Kaisho, 2019, International immunology.

Involvement of TLR4/MD-2 complex in species-specific lipopolysaccharide-mimetic signal transduction by Taxol

T. Yoshida, K. Miyake, M. Nishijima, 2001, Journal of endotoxin research.

Chemical synthesis of Helicobacter pylori lipopolysaccharide partial structures and their selective proinflammatory responses.

K. Fukase, K. Miyake, H. Tsutsui, 2011, Chemistry.

A single base mutation in the PRAT4A gene reveals differential interaction of PRAT4A with Toll-like receptors.

Y. Seto, K. Miyake, C. Nishitani, 2008, International immunology.

RP105 facilitates macrophage activation by Mycobacterium tuberculosis lipoproteins.

J. Ernst, A. Blumenthal, K. Miyake, 2009, Cell host & microbe.

Toll-Like Receptor 4 Expression Is Required to Control Chronic Mycobacterium tuberculosis Infection in Mice

B. Ryffel, F. Bihl, K. Miyake, 2002 .

This information is current as Infection in Mice tuberculosis Mycobacterium to Control Chronic Toll-Like Receptor 4 Expression Is Required

B. Ryffel, F. Bihl, K. Miyake, 2002 .

Nucleosides drive histiocytosis in SLC29A3 disorders by activating TLR7

T. Ichinohe, Toshiyuki Shimizu, N. Yoshida, 2019, bioRxiv.

Unc93 homolog B1 restricts systemic lethal inflammation by orchestrating TLR7 and TLR9 response

S. Akira, M. Matsumoto, N. Yoshida, 2012, Arthritis Research & Therapy.

Dynamic control of nucleic-acid-sensing Toll-like receptors by the endosomal compartment.

K. Miyake, Y. Murakami, S. Saitoh, 2021, International immunology.

Evidence for existence of two distinct TNP-Ficoll-responsive B cell subpopulations preferentially reactive either to a T cell-replacing factor (B151-TRF) or to a signal from accessory cells.

K. Takatsu, K. Miyake, T. Hamaoka, 1986, Journal of immunology.

Association of SIGNR 1 with TLR 4 – MD2 enhances signal transduction by recognition of LPS in gram-negative bacteria

R. Steinman, K. Miyake, K. Takahara, 2005 .

Increase of RP105-lacking activated B cells in the peripheral blood and salivary glands in patients with Sjögren's syndrome.

S. Nakamura, T. Horiuchi, K. Miyake, 2008, Clinical and experimental rheumatology.

Palmitoylation of LAT contributes to its subcellular localization and stability.

K. Miyake, S. Kawano, S. Saitoh, 2006, Biochemical and biophysical research communications.

Shigella protein IpaH ( 9 . 8 ) is secreted from bacteria within mammalian cells and transported to the nucleus

Hirotaka, K. Fukase, Y. Nagai, 2002 .

Murine B cell proliferation and protection from apoptosis with an antibody against a 105-kD molecule: unresponsiveness of X-linked immunodeficient B cells

Y. Hitoshi, K. Takatsu, K. Miyake, 1994, The Journal of experimental medicine.

Requirement for VLA-4 and VLA-5 integrins in lymphoma cells binding to and migration beneath stromal cells in culture

K. Miyake, M. Kimoto, H. Yagita, 1992, The Journal of cell biology.

Production Homeostatic Proliferation , Cell Survival , and The Role of IL-5 for Mature B-1 Cells in Kiyoshi

K. Takatsu, B. Moon, S. Takaki, 2004 .

Dendritic Cells Triggers Induction of IL-12, Activation of Toll-Like Receptor 2 on Human

M. Roth, P. Godowski, K. Miyake, 2013 .

Expression of TLR4 4 (PRAT4A) Regulates Cell Surface A Protein Associated with Toll-Like Receptor

T. Mizutani, H. Iba, Y. Ishihama, 2013 .

MD-2 is required for the full responsiveness of mast cells to LPS but not to PGN.

A. Nakao, K. Miyake, K. Okumura, 2004, Biochemical and biophysical research communications.

Toll-Like Receptor 4 Mediates the Antitumor Host Response Induced by a 55-Kilodalton Protein Isolated from Aeginetia indica L., a Parasitic Plant

S. Akira, O. Takeuchi, K. Miyake, 2004, Clinical Diagnostic Laboratory Immunology.

Essential role of MD-2 in B-cell responses to lipopolysaccharide and Toll-like receptor 4 distribution

Y. Nagai, K. Miyake, S. Akashi, 2002, Journal of endotoxin research.

Possible Involvement of Toll-Like Receptor 4 in Endothelial Cell Activation of Larger Vessels in Response to Lipopolysaccharide

K. Miyake, K. Matsuura, N. Hijiya, 2002, Pathobiology.

Gram-Negative Bacteria and Their Cell TLR 2-Mediated Responses to Gram-Positive Lipopolysaccharide and Enhances ( TLR 2 )-Mediated Responses to MD2 Enables Toll-Like Receptor 2

K. Miyake, R. Dziarski, D. Gupta, 2001 .

Receptor 4 Expression Down-Regulation of Surface Toll-Like Peritoneal Macrophages Correlates with Cutting Edge: Endotoxin Tolerance in Mouse

S. Akira, Shintaro Sato, T. Kawai, 2000 .

Translocation of NF-Toll-Like Receptor 4 ( TLR 4 ) Prior to Nuclear Physical Proximity Between CD 14 and Cutting Edge : Lipopolysaccharide Induces

K. Miyake, S. Akashi, Q. Jiang, 2000 .

Mouse Peritoneal Macrophages Toll-Like Receptor 4-MD2 Complex on Lipopolysaccharide Signaling Via the Cutting Edge : Cell Surface Expression and

K. Takeda, Y. Nagai, K. Miyake, 2000 .

The Toll-like Receptor Protein Rp105 Regulates Lipopolysaccharide Signaling in B Cells

K. Rajewsky, A. Tarakhovsky, Y. Nagai, 2000, The Journal of experimental medicine.

Inflammatory responses increase secretion of MD-1 protein.

K. Takatsu, S. Haga, M. Ozaki, 2016, International immunology.

The RP105/MD-1 complex is indispensable for TLR4/MD-2-dependent proliferation and IgM-secreting plasma cell differentiation of marginal zone B cells.

K. Takatsu, S. Ohta, Y. Nagai, 2012, International immunology.

Potentiation of TLR9 responses for human naïve B-cell growth through RP105 signaling.

H. Ochs, K. Miyake, Takuma Hayashi, 2010, Clinical immunology.

Tonic B cell activation by Radioprotective105/MD-1 promotes disease progression in MRL/lpr mice.

S. Akira, H. Kiyono, Y. Nagai, 2008, International immunology.

Difference in B cell activation between dermatomyositis and polymyositis: analysis of the expression of RP105 on peripheral blood B cells

T. Horiuchi, K. Miyake, Y. Tada, 2001, Annals of the rheumatic diseases.

Molecular cloning of a human RP105 homologue and chromosomal localization of the mouse and human RP105 genes (Ly64 and LY64).

J. Inazawa, N. Copeland, D. Gilbert, 1996, Genomics.

Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production.

S. Akira, T. Kaisho, K. Takatsu, 2009, Molecular immunology.

[Toll-like receptors and their roles in defense responses against infection].

K. Miyake, 2003, Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases.

Innate recognition of lipopolysaccharide by CD14 and toll-like receptor 4-MD-2: unique roles for MD-2.

K. Miyake, 2003, International immunopharmacology.

Interleukin-33 produced by M2 macrophages and other immune cells contributes to Th2 immune reaction of IgG4-related disease

T. Sumida, K. Miyake, H. Tsuboi, 2017, Scientific Reports.

Aggregation makes a protein allergenic at the challenge phase of basophil-mediated allergy in mice

H. Karasuyama, K. Miyake, Y. Yamanishi, 2018, International immunology.

Identification of genes expressed in tumor-associated macrophages.

R. Andreesen, K. Miyake, L. Kunz-Schughart, 2003, Immunobiology.

Role of the endothelial adhesion molecule VCAM in murine cardiac allograft rejection.

C. Orosz, R. Pelletier, D. Sedmak, 1992, Immunology letters.

Basophils, a neglected minority in the immune system, have come into the limelight at last.

H. Karasuyama, K. Miyake, S. Shibata, 2021, International immunology.

Intracellular TLR4/MD-2 in macrophages senses Gram-negative bacteria and induces a unique set of LPS-dependent genes.

K. Miyake, S. Akashi-Takamura, Takuma Shibata, 2011, International immunology.

Cleavage of Toll-Like Receptor 9 Ectodomain Is Required for In Vivo Responses to Single Strand DNA

N. Yoshida, K. Miyake, Y. Murakami, 2018, Front. Immunol..

TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells

Katsuaki Sato, M. Oyama, T. Katada, 2017, Nature Communications.

CD44 and other cell interaction molecules contributing to B lymphopoiesis.

K. Ishihara, Q. He, K. Miyake, 1993, Current topics in microbiology and immunology.

Evidencefora RoleoftheIntegrinVLA 4 in Lympho-hemopoiesis

J. Greenberger, K. Miyake, Irving L. Weissmanj, 1991 .

Myeloid differentiation protein‐2 has a protective role in house dust mite‐mediated asthmatic characteristics with the proinflammatory regulation of airway epithelial cells and dendritic cells

K. Miyake, Y. Murakami, T. Nagase, 2021, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Trogocytosis of peptide–MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils

H. Karasuyama, K. Miyake, Y. Yamanishi, 2017, Proceedings of the National Academy of Sciences.

Essential role of MD-2 in LPS responsiveness and TLR4 distribution

S. Akira, T. Kitamura, Y. Iwakura, 2002, Nature Immunology.

The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane.

Toshiyuki Shimizu, K. Fukase, K. Miyake, 2014, International immunology.

For Peer Review The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of TLR4/MD2 complex at the plasma membrane

K. Miyake, 2013 .

ANALYSIS OF INFLAMMATORY ENDOTHELIAL CHANGES, INCLUDING VCAM‐1 EXPRESSION, IN MURINE CARDIAC GRAFTS1,2

C. Orosz, R. Pelletier, D. Sedmak, 1993, Transplantation.

TLRsExoenzyme S Activate Distinct Different Domains of Pseudomonas

C. Mody, K. Miyake, D. Woods, 2013 .

Different Domains of Pseudomonas aeruginosa Exoenzyme S Activate Distinct TLRs1

P. Kubes, C. Mody, K. Miyake, 2004, The Journal of Immunology.

TLRs Exoenzyme S Activate Distinct aeruginosa Pseudomonas Different Domains of

P. Kubes, C. Mody, K. Miyake, 2004 .

Cytidine deaminase enables Toll-like receptor 8 activation by cytidine or its analogs

T. Ichinohe, K. Miyake, M. Moriyama, 2018, International immunology.

Endocytosis‐free DNA sensing by cell surface TLR9 in neutrophils: Rapid defense with autoimmune risks

K. Miyake, M. Onji, 2013, European journal of immunology.

Lipopeptides are signaled by Toll-like receptor 1, 2 and 6 in endolysosomes.

K. Miyake, Y. Murakami, T. Kasahara, 2014, International immunology.

Skin‐infiltrating basophils promote atopic dermatitis‐like inflammation via IL‐4 production in mice

H. Karasuyama, K. Miyake, Y. Yamanishi, 2020, Allergy.

Biallelic Variants in CNPY3, Encoding an Endoplasmic Reticulum Chaperone, Cause Early-Onset Epileptic Encephalopathy.

H. Kitaura, A. Kakita, H. Mutoh, 2018, American journal of human genetics.

Up-regulation of α4 integrin on activated langerhans cells: Analysis of adhesion molecules on langerhans cells relating to their migration from skin to draining lymph nodes

S. Nakagawa, H. Tagami, S. Aiba, 1993 .

Up-regulation of alpha 4 integrin on activated Langerhans cells: analysis of adhesion molecules on Langerhans cells relating to their migration from skin to draining lymph nodes.

S. Nakagawa, H. Tagami, S. Aiba, 1993, The Journal of investigative dermatology.

Skin CD4+ Memory T Cells Play an Essential Role in Acquired Anti-Tick Immunity through Interleukin-3-Mediated Basophil Recruitment to Tick-Feeding Sites

H. Yonekawa, H. Shitara, H. Karasuyama, 2017, Front. Immunol..

Real-time imaging of mast cell degranulation in vitro and in vivo.

H. Karasuyama, K. Miyake, Y. Yamanishi, 2016, Biochemical and biophysical research communications.

Regulatory T Cells MD1 Expression Regulates Development of

K. Miyake, R. Gorczynski, Y. Kai, 2022 .

Recent advances in understanding basophil‐mediated Th2 immune responses

H. Tsutsui, H. Karasuyama, K. Miyake, 2017, Immunological reviews.

Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors

D. Nemazee, K. Miyake, Y. Murakami, 2021, Nature Communications.

Saccharomyces cerevisiae‐ and Candida albicans‐Derived Mannan Induced Production of Tumor Necrosis Factor Alpha by Human Monocytes in a CD14‐ and Toll‐Like Receptor 4‐Dependent Manner

E. Nemoto, H. Shimauchi, K. Shibata, 2002, Microbiology and immunology.

Stromal-Cell and Cytokine-Dependent Lymphocyte Clones Which Span the Pre-B- to B-Cell Transition

K. Ishihara, K. Miyake, K. Medina, 1991, Developmental immunology.

Mucolipin 1 positively regulates TLR7 responses in dendritic cells by facilitating RNA transportation to lysosomes.

K. Miyake, S. Saitoh, Ryutaro Fukui, 2015, International immunology.

IMPDH inhibition activates TLR‐VCAM1 pathway and suppresses the development of MLL‐fusion leukemia

T. Shibata, S. Yamasaki, A. Sasaki, 2022, EMBO molecular medicine.

Arl8b is required for lysosomal degradation of maternal proteins in the visceral yolk sac endoderm of mouse embryos

T. Katada, M. Suematsu, M. Miura, 2017, Journal of Cell Science.

Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long- term bone marrow cultures

K. Miyake, T. Hamaoka, K. Medina, 1990, The Journal of experimental medicine.

Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA.

Toshiyuki Shimizu, M. Taoka, Y. Yamauchi, 2016, Immunity.

Toll-like receptor 8 senses degradation products of single-stranded RNA

Toshiyuki Shimizu, M. Taoka, Y. Yamauchi, 2015, Nature Structural &Molecular Biology.

Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex

T. Hirokawa, Toshiyuki Shimizu, K. Takatsu, 2017, The Journal of Biological Chemistry.

Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation.

D. Golenbock, K. Miyake, K. Triantafilou, 2002, Journal of cell science.

Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

M. T. Wong, V. Dixit, Juan Zhang, 2013, Science.

The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase

Hiroyuki Aburatani, Shizuo Akira, H. Aburatani, 2008, Nature Cell Biology.

Cutting Edge: Cell Surface Expression and Lipopolysaccharide Signaling Via the Toll-Like Receptor 4-MD-2 Complex on Mouse Peritoneal Macrophages1

K. Takeda, Y. Nagai, K. Miyake, 2000, The Journal of Immunology.

Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors.

K. Miyake, 2007, Seminars in immunology.

Lipopolysaccharide Interaction with Cell Surface Toll-like Receptor 4-MD-2

K. Fukase, Y. Nagai, K. Miyake, 2003, The Journal of experimental medicine.

Cutting Edge: Endotoxin Tolerance in Mouse Peritoneal Macrophages Correlates with Down-Regulation of Surface Toll-Like Receptor 4 Expression1

S. Akira, Shintaro Sato, K. Takeda, 2000, The Journal of Immunology.

Polyclonal B cell activation by a B cell differentiation factor, B151-TRF2. II. Evidence for interaction of B151-TRF2 with glycoprotein on B cell membrane via recognition of terminal N-acetyl-D-glucosamine residue(s).

Y. Takahama, K. Miyake, T. Hamaoka, 1986, Journal of Immunology.

Bortezomib suppresses function and survival of plasmacytoid dendritic cells by targeting intracellular trafficking of Toll-like receptors and endoplasmic reticulum homeostasis.

N. Kadowaki, S. Kamihira, K. Miyake, 2011, Blood.

Core fucose is critical for CD14-dependent Toll-like receptor 4 signaling

N. Taniguchi, Yasuhiko Kizuka, S. Kitazume, 2017, Glycobiology.

Cell activation by Porphyromonas gingivalis lipid A molecule through Toll-like receptor 4- and myeloid differentiation factor 88-dependent signaling pathway.

S. Akira, T. Ogawa, Y. Asai, 2002, International immunology.

Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4

T. Ahrens, J. Simon, C. Fieber, 2002, The Journal of experimental medicine.

UNC93B1 is essential for the plasma membrane localization and signaling of Toll-like receptor 5

K. Miyake, You-Me Kim, Ryutaro Fukui, 2014, Proceedings of the National Academy of Sciences.

Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain

R. Morita, S. Akira, A. Yoshimura, 2012, Nature Medicine.

Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization.

Makiko Kobayashi, K. Fukase, Y. Nagai, 2004, International immunology.

Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition.

K. Fukase, Y. Nagai, K. Miyake, 2001, International immunology.

Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog

R. Ray, M. Lai, R. Deshaies, 2009, Proceedings of the National Academy of Sciences.

The Radioprotective 105/MD-1 Complex Links TLR2 and TLR4/MD-2 in Antibody Response to Microbial Membranes1

S. Akira, T. Kaisho, M. Matsumoto, 2005, The Journal of Immunology.

Species-Specific Minimal Sequence Motif for Oligodeoxyribonucleotides Activating Mouse TLR9

K. Miyake, R. Jerala, M. Benčina, 2015, The Journal of Immunology.

E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates

Mahmoud A. Bassal, D. Tenen, M. Tsai, 2021, Science Immunology.

Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia

H. Kuroda, R. Takimoto, Y. Niitsu, 2003, Nature Medicine.

Basophils trigger emphysema development in a murine model of COPD through IL-4–mediated generation of MMP-12–producing macrophages

H. Karasuyama, K. Miyake, Y. Yamanishi, 2018, Proceedings of the National Academy of Sciences.

RP105 is associated with MD-1 and transmits an activation signal in human B cells.

Y. Narisawa, K. Miyake, M. Kimoto, 1998, Blood.

Endolysosomal compartments as platforms for orchestrating innate immune and metabolic sensors

K. Miyake, Y. Murakami, S. Saitoh, 2019, Journal of leukocyte biology.

New application of anti-TLR monoclonal antibodies: detection, inhibition and protection

K. Miyake, Y. Murakami, Ryutaro Fukui, 2018, Inflammation and Regeneration.

C4b‐binding protein negatively regulates TLR4/MD‐2 response but not TLR3 response

K. Miyake, Y. Murakami, S. Akashi-Takamura, 2017, FEBS letters.

Selectivity of Human TLR9 for Double CpG Motifs and Implications for the Recognition of Genomic DNA

K. Miyake, R. Jerala, M. Benčina, 2017, The Journal of Immunology.

This information is current as of Genomic DNA Motifs and Implications for the Recognition Selectivity of Human TLR 9 for Double CpG

K. Miyake, R. Jerala, Ryutaro Fukui, 2017 .

Homeostatic Inflammation as Environmental-Adaptation Strategy

K. Miyake, Ryutaro Fukui, 2016 .

Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

Toshiyuki Shimizu, S. Uchiyama, Elena Krayukhina, 2015, Nature.

Serum Amyloid A3 Binds MD-2 To Activate p38 and NF-κB Pathways in a MyD88-Dependent Manner

K. Miyake, Satoshi Takahashi, S. Akashi-Takamura, 2013, The Journal of Immunology.

Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci

H. Aburatani, H. Kijima, M. Murakami, 2013, Nature Communications.

Structural Reorganization of the Toll-Like Receptor 8 Dimer Induced by Agonistic Ligands

Takuma Shibata, Toshiyuki Shimizu, Toshiyuki Shimizu, 2013, Science.

Human TLR4 polymorphism D299G/T399I alters TLR4/MD-2 conformation and response to a weak ligand monophosphoryl lipid A.

Toshiyuki Shimizu, K. Miyake, T. Suganami, 2013, International immunology.

MyD 88-Dependent Manner B Pathways in a κ p 38 and NF-Serum Amyloid A 3 Binds MD2 To Activate

K. Miyake, Satoshi Takahashi, S. Akashi-Takamura, 2013 .

Structural Analyses of Human Toll-like Receptor 4 Polymorphisms D299G and T399I*

Toshiyuki Shimizu, K. Miyake, S. Akashi-Takamura, 2012, The Journal of Biological Chemistry.

Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2

Koichi Fukase, Toshiyuki Shimizu, Toshiyuki Shimizu, 2012, Proceedings of the National Academy of Sciences.

Crystal structures of mouse and human RP105/MD-1 complexes reveal unique dimer organization of the toll-like receptor family.

Toshiyuki Shimizu, K. Miyake, U. Ohto, 2011, Journal of molecular biology.

Crystal Structures of Human MD-2 and Its Complex with Antiendotoxic Lipid IVa

Y. Satow, K. Fukase, K. Miyake, 2007, Science.

Regulatory Roles for MD-2 and TLR4 in Ligand-Induced Receptor Clustering1

Makiko Kobayashi, K. Fukase, K. Miyake, 2006, The Journal of Immunology.

Human B Cells RP105 Is Associated With MD-1 and Transmits an Activation Signal in

Y. Narisawa, K. Miyake, M. Kimoto, 2013 .

Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide.

Y. Iwakura, Y. Nagai, K. Miyake, 2002, Blood.

Is Associated With MD-1 and Transmits an Activation Signal in Human B Cells

Y. Narisawa, K. Miyake, M. Kimoto, 1998 .

Basophils and their effector molecules in allergic disorders

H. Karasuyama, K. Miyake, S. Shibata, 2020, Allergy.

A Protein Associated with Toll-Like Receptor 4 (PRAT4A) Regulates Cell Surface Expression of TLR41

T. Mizutani, H. Iba, Y. Ishihama, 2006, The Journal of Immunology.

MD1 Expression Regulates Development of Regulatory T Cells

K. Miyake, R. Gorczynski, Y. Kai, 2006, The Journal of Immunology.

A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression.

T. Ishii, Makiko Kobayashi, K. Miyake, 2006, Biochemical and biophysical research communications.

Molecular mechanism for innate recognition of microbial products by toll-like receptors

K. Miyake, 2005 .

Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line A Point Mutation in a Conserved Region of Md-2 Abolishes Endotoxin-Induced Signaling

D. Schwartz, B. Monks, D. Golenbock, 2001 .

Expression of Toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritis.

P. Godowski, K. Miyake, H. Makino, 2004, Arthritis and rheumatism.

Role of TLR4/MD-2 and RP105/MD-1 in Innate Recognition of Lipopolysaccharide

K. Miyake, M. Kimoto, K. Nagasawa, 2003, Scandinavian journal of infectious diseases.

Micrococcus luteus Teichuronic Acids Activate Human and Murine Monocytic Cells in a CD14- and Toll-Like Receptor 4-Dependent Manner

K. Miyake, Y. Adachi, M. Nishijima, 2001, Infection and Immunity.

MD-2 Enables Toll-Like Receptor 2 (TLR2)-Mediated Responses to Lipopolysaccharide and Enhances TLR2-Mediated Responses to Gram-Positive and Gram-Negative Bacteria and Their Cell Wall Components1

K. Miyake, R. Dziarski, D. Gupta, 2001, The Journal of Immunology.

A calcium- or manganese-dependent epitope on the integrin beta 1 chain recognized by a unique mAb.

K. Miyake, M. Kimoto, Y. Yamashita, 1994, International immunology.

The Chaperone UNC93B1 Regulates Toll‐like Receptor Stability Independently of Endosomal TLR Transport

N. Hacohen, F. Meissner, E. Latz, 2018, Immunity.

Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation.

J. Cavaillon, K. Asehnoune, K. Miyake, 2003, American journal of respiratory and critical care medicine.

TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes.

Y. Okamura, K. Takeda, Y. Sakata, 2020, Cell Reports.

The Molecular Mechanism of B Cell Activation by toll-like Receptor Protein RP-105

K. Rajewsky, A. Tarakhovsky, M. Leitges, 1998, The Journal of experimental medicine.

The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell surface glycoproteins [published erratum appears in J Cell Biol 1991 Feb;112(3):following 513]

E. Butcher, K. Miyake, M. Culty, 1990, The Journal of cell biology.

Dok-1 and Dok-2 are negative regulators of lipopolysaccharide-induced signaling

Y. Iwakura, H. Karasuyama, Y. Nagai, 2005, The Journal of experimental medicine.

Immunobiology of Acquired Resistance to Ticks

H. Karasuyama, K. Miyake, S. Yoshikawa, 2020, Frontiers in Immunology.

TLR accessory molecules.

K. Miyake, S. Akashi-Takamura, Kensuke Miyake, 2008, Current opinion in immunology.

Effects of Overexpression of PTP36, a Putative Protein Tyrosine Phosphatase, on Cell Adhesion, Cell Growth, and Cytoskeletons in HeLa Cells*

K. Miyake, T. Hamaoka, A. Kosugi, 1999, The Journal of Biological Chemistry.

The role of basophils in acquired protective immunity to tick infestation

H. Karasuyama, K. Miyake, A. Kamiya, 2020, Parasite immunology.

Critical role for Ets, AP-1 and GATA-like transcription factors in regulating mouse Toll-like receptor 4 (Tlr4) gene expression.

I. Miconnet, T. Calandra, H. Kai, 2005, The Biochemical journal.

Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands.

Toshiyuki Shimizu, M. Taoka, Y. Yamauchi, 2018, Cell reports.

Histamine Released From Skin-Infiltrating Basophils but Not Mast Cells Is Crucial for Acquired Tick Resistance in Mice

T. Adachi, H. Karasuyama, K. Miyake, 2018, Front. Immunol..

Regulatory molecules required for nucleotide‐sensing Toll‐like receptors

K. Miyake, S. Saitoh, 2009, Immunological reviews.

Toll‐like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation

Toshiyuki Shimizu, K. Miyake, Takuma Shibata, 2018, Immunity.

Modulation of TCR-mediated signaling pathway by thymic shared antigen-1 (TSA-1)/stem cell antigen-2 (Sca-2).

Y. Minami, K. Miyake, T. Hamaoka, 1995, Journal of immunology.

Mast cell‐mediated immune responses through IgE antibody and Toll‐like receptor 4 by malarial peroxiredoxin

K. Miyake, H. Fukuda, S. Kano, 2008, European journal of immunology.

Endotoxin recognition molecules, Toll-like receptor 4-MD-2.

K. Miyake, 2004, Seminars in immunology.

N6-methylated adenine on the target sites of mamA from Mycobacterium bovis BCG enhances macrophage activation by CpG DNA in mice.

K. Miyake, M. Ato, T. Tamura, 2020, Tuberculosis.

Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function

K. Ishii, S. Akira, K. Ikeda, 2019, Life Science Alliance.

The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages.

E. Latz, S. Yamazaki, H. Tsukamoto, 2020, International immunology.

Activated M2 Macrophages Contribute to the Pathogenesis of IgG4‐Related Disease via Toll‐like Receptor 7/Interleukin‐33 Signaling

Hidetaka Yamamoto, K. Miyake, Y. Murakami, 2019, Arthritis & rheumatology.

Type I IFN Contributes to the Phenotype of Unc93b1D34A/D34A Mice by Regulating TLR7 Expression in B Cells and Dendritic Cells

K. Miyake, Ryutaro Fukui, Atsuo Kanno, 2016, The Journal of Immunology.

Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking.

S. Akira, M. Matsumoto, N. Yoshida, 2011, Immunity.

Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing

M. Oyama, B. Beutler, H. Kozuka-Hata, 2009, The Journal of experimental medicine.

Toll‐like Receptors

K. Miyake, T. Seya, 2009 .

Mechanism regulating cell surface expression and activation of Toll-like receptor 4.

K. Miyake, S. Saitoh, 2006, Chemical record.

Ligand-Induced Receptor Clustering Regulatory Roles for MD2 and TLR 4 in and Kensuke

Makiko Kobayashi, K. Fukase, K. Miyake, 2006 .

TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction

M. Ikeguchi, H. Shigematsu, Toshiyuki Shimizu, 2023, Nature Communications.

Nucleic acid‐sensing TLRs and autoimmunity: novel insights from structural and cell biology

E. Latz, K. Miyake, K. Pelka, 2016, Immunological reviews.

A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses

K. Takatsu, Y. Nagai, K. Miyake, 2007, The Journal of experimental medicine.

Toll-like receptor homolog RP 105 modulates the antigen-presenting cell function and regulates the development of collagen-induced arthritis

H. Inoue, K. Miyake, Y. Tada, 2015 .

Toll-like receptor homolog RP105 modulates the antigen-presenting cell function and regulates the development of collagen-induced arthritis

H. Inoue, K. Miyake, Y. Tada, 2008, Arthritis research & therapy.

Requirements for hyaluronic acid binding by CD44: a role for the cytoplasmic domain and activation by antibody

Q. He, K. Miyake, R. Hyman, 1992, The Journal of experimental medicine.

Crystal structure of NOD2 and its implications in human disease

Toshiyuki Shimizu, K. Miyake, Takuma Shibata, 2016, Nature Communications.

Double-stranded RNA of intestinal commensal but not pathogenic bacteria triggers production of protective interferon-β.

S. Akira, T. Kaisho, O. Takeuchi, 2013, Immunity.

B Lymphocytes Differentially Use the Rel and Nuclear Factor κB1 (NF-κB1) Transcription Factors to Regulate Cell Cycle Progression and Apoptosis in Quiescent and Mitogen-activated Cells

A. Strasser, S. Gerondakis, R. Grumont, 1998, The Journal of experimental medicine.

Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression.

K. Miyake, M. Kimoto, J. Kondo, 1998, Journal of immunology.

Its Expression Associated with RP 105 and Positively Regulates Mouse MD-1 , a Molecule That Is Physically

K. Miyake, M. Kimoto, J. Kondo, 1998 .

Activation of Toll-Like Receptor 2 on Human Dendritic Cells Triggers Induction of IL-12, But Not IL-101

P. Godowski, K. Miyake, M. Norgard, 2000, The Journal of Immunology.

Targeting cell surface TLR7 for therapeutic intervention in autoimmune diseases

Toshiyuki Shimizu, Kazuhide Yamamoto, K. Miyake, 2015, Nature Communications.

Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling.

K. Miyake, S. Saitoh, S. Akashi-Takamura, 2008, Biochemical and biophysical research communications.

Cathepsins are required for Toll-like receptor 9 responses.

K. Miyake, S. Saitoh, S. Akashi-Takamura, 2008, Biochemical and biophysical research communications.

Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition

K. Miyake, P. Kincade, C. Underhill, 1990, The Journal of experimental medicine.

The enzyme Cyp26b1 mediates inhibition of mast cell activation by fibroblasts to maintain skin-barrier homeostasis.

S. Akira, M. Kubo, H. Kiyono, 2014, Immunity.

Role of the Toll-like Receptor 4/NF-&kgr;B Pathway in Saturated Fatty Acid–Induced Inflammatory Changes in the Interaction Between Adipocytes and Macrophages

S. Yamaoka, Y. Kamei, H. Kotani, 2007, Arteriosclerosis, thrombosis, and vascular biology.

High-Density Lipoprotein Suppresses the Type I Interferon Response, a Family of Potent Antiviral Immunoregulators, in Macrophages Challenged With Lipopolysaccharide

Roger E Bumgarner, Masashi Suzuki, R. Beyer, 2010, Circulation.

Involvement of very late activation antigen 4 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) in tumor necrosis factor alpha enhancement of experimental metastasis.

K. Miyake, K. Okumura, H. Yagita, 1994, Cancer research.

Agonistic Antibody to TLR4/MD-2 Protects Mice from Acute Lethal Hepatitis Induced by TNF-α1

K. Miyake, Y. Adachi, S. Saitoh, 2006, The Journal of Immunology.

Lipopolysaccharide Preparation Extracted from Porphyromonas gingivalis Lipoprotein-Deficient Mutant Shows a Marked Decrease in Toll-Like Receptor 2-Mediated Signaling

S. Akira, T. Ogawa, Y. Asai, 2005, Infection and Immunity.

Mouse Toll-like Receptor 4·MD-2 Complex Mediates Lipopolysaccharide-mimetic Signal Transduction by Taxol*

T. Yoshida, K. Miyake, M. Nishijima, 2000, The Journal of Biological Chemistry.

Obesity-associated autoantibody production requires AIM to retain the immunoglobulin M immune complex on follicular dendritic cells.

O. Ohara, Quanzhen Li, E. Wakeland, 2013, Cell reports.

RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family.

K. Miyake, M. Kimoto, Y. Yamashita, 1995, Journal of immunology.

HEMATOPOIESIS Stromal Cell CD 9 Regulates Differentiation of Hematopoietic Stem / Progenitor Cells

Y. Matsuzawa, T. Nishiura, J. Ishikawa, 1999 .

Functional Association of CD9 with the Fcγ Receptors in Macrophages1

S. Takeshita, K. Miyake, A. Kudo, 2001, The Journal of Immunology.

TLR4–MD-2 complex is negatively regulated by an endogenous ligand, globotetraosylceramide

Kazuro Furukawa, K. Ikeda, R. Taguchi, 2013, Proceedings of the National Academy of Sciences.

STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes

Hiroyuki Arai, G. Barber, Takehiro Suzuki, 2023, Nature Cell Biology.

Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses

K. Miyake, T. Takai, S. Saitoh, 2015, The Journal of Immunology.

Multifaceted roles of basophils in health and disease.

H. Karasuyama, K. Miyake, Y. Yamanishi, 2017, The Journal of allergy and clinical immunology.

Regulatory roles for CD14 and phosphatidylinositol in the signaling via toll-like receptor 4-MD-2.

T. Kirikae, K. Fukudome, Y. Nagai, 2000, Biochemical and biophysical research communications.

Retinal cell type‐specific prevention of ischemia‐induced damages by LPS‐TLR4 signaling through microglia

K. Ishii, S. Akira, H. Ueda, 2013, Journal of neurochemistry.

term cultures Antibody ligation of CD9 modifies production of myeloid cells in long

J. Gimble, J. Hudson, K. Miyake, 2011 .

The Origin of Antibody‐Forming Cells Detected in the Bone Marrow after Thymus‐Independent Antigen‐Stimulation and Abnormality in Migration of B Cells of X‐Linked Immunodeficient CBA/N Mice

K. Miyake, T. Hamaoka, S. Ono, 1987, Microbiology and immunology.

CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes.

S. Akira, M. Fujimoto, K. Takeda, 2003, Blood.

TNF-byMice from Acute Lethal Hepatitis Induced Agonistic Antibody to TLR 4 / MD2 Protects

K. Miyake, Y. Adachi, S. Saitoh, 2006 .

How do basophils contribute to Th2 cell differentiation and allergic responses?

H. Karasuyama, K. Miyake, Y. Yamanishi, 2018, International immunology.

Glycyrrhizin and isoliquiritigenin suppress the LPS sensor Toll‐like receptor 4/MD‐2 complex signaling in a different manner

K. Takatsu, H. Hayashi, Y. Nagai, 2012, Journal of leukocyte biology.

An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing

H. Kiyono, Shintaro Sato, Kazuhide Yamamoto, 2013, Nature Communications.

The CD9 Molecule on Stromal Cells

K. Miyake, P. Kincade, S. Hayashi, 2000, Leukemia & lymphoma.

Response to Microbial Membranes Links TLR2 and TLR4/MD-2 in Antibody The Radioprotective 105/MD-1 Complex

S. Akira, T. Kaisho, M. Matsumoto, 2005 .

Expression of VLA-4 on thymocytes. Maturation stage-associated transition and its correlation with their capacity to adhere to thymic stromal cells.

K. Miyake, T. Hamaoka, K. Takeda, 1992, Journal of immunology.

Association of a tetraspanin CD9 with CD5 on the T cell surface: role of particular transmembrane domains in the association.

Y. Yashiro‐Ohtani, H. Fujiwara, K. Miyake, 1999, International immunology.

IL-5 induces a Pgp-1 (CD44) bright B cell subpopulation that is highly enriched in proliferative and Ig secretory activity and binds to hyaluronate.

C. June, R. Hodes, K. Miyake, 1990, Journal of immunology.

Tolerogenic properties of CD206+ macrophages appeared in the sublingual mucosa after repeated antigen-painting.

H. Karasuyama, K. Miyake, M. Azuma, 2020, International immunology.

RP105-lacking B cells from lupus patients are responsible for the production of immunoglobulins and autoantibodies.

T. Horiuchi, K. Miyake, M. Kimoto, 2002, Arthritis and rheumatism.

Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8

Takuma Shibata, Toshiyuki Shimizu, Toshiyuki Shimizu, 2016, Proceedings of the National Academy of Sciences.

Non-CD28 Costimulatory Molecules Present in T Cell Rafts Induce T Cell Costimulation by Enhancing the Association of TCR with Rafts1

Y. Yashiro‐Ohtani, H. Fujiwara, R. Abe, 2000, The Journal of Immunology.

TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells

Katsuaki Sato, M. Oyama, T. Katada, 2017, Nature Communications.

Crystal structure of human MD-2 in complex with lipid IVa

Y. Satow, K. Fukase, K. Miyake, 2007 .

Functional association of CD9 with the Fc gamma receptors in macrophages.

S. Takeshita, K. Miyake, A. Kudo, 2001, Journal of immunology.

Ligand-dependent Toll-like receptor 4 (TLR4)-oligomerization is directly linked with TLR4-signaling

K. Fukase, K. Miyake, S. Kusumoto, 2004, Journal of endotoxin research.

Pre-B cells adhere to fibronectin via interactions of integrin α5/αv with RGDS as well as of integrin α4 with two distinct V region sequences at its different binding sites

H. Fujiwara, Y. Oka, H. Sugiyama, 1994 .

TLR7/8 stress response drives histiocytosis in SLC29A3 disorders

Y. Furukawa, T. Ichinohe, E. Latz, 2022, bioRxiv.

B cells lacking RP105, a novel B cell antigen, in systemic lupus erythematosus.

K. Miyake, M. Kimoto, Y. Tada, 1999, Arthritis and rheumatism.

Single cell transcriptomics clarifies the basophil differentiation trajectory and identifies pre-basophils upstream of mature basophils

H. Karasuyama, K. Miyake, J. Nakabayashi, 2023, Nature communications.

New application of anti-TLR monoclonal antibodies: detection, inhibition and protection

K. Miyake, Y. Murakami, Ryutaro Fukui, 2018, Inflammation and regeneration.

The anti‐TLR4 monoclonal antibody Sa15‐21 enhances inflammatory cytokine production in LPS‐stimulated macrophages

K. Miyake, Susumu Tomono, S. Saitoh, 2023, FEBS Letters.

in B lymphocytes CD19 regulates innate immunity by the toll-like receptor RP105 signaling

S. Akira, M. Fujimoto, K. Takeda, 2013 .

Microbiome ssRNA as an environmental cue to activate TLR13-dependent tissue-protective programs in CD5Lhi hepatic macrophages

Y. Furukawa, T. Kaisho, E. Latz, 2023, bioRxiv.

Editorial overview: Special section: effects of endogenous immune stimulants: from a defence system against infection to a homeostatic mechanism linking metabolism with inflammation.

E. Latz, K. Miyake, 2014, Current opinion in immunology.

Extracellular aaRSs drive autoimmune and inflammatory responses in rheumatoid arthritis via the release of cytokines and PAD4

H. Takayanagi, H. Imataka, K. Miyake, 2023, Annals of the Rheumatic Diseases.

Peptide‐binding motifs of the mixed haplotype Aβz/Aαd major histocompatibility complex class II molecule: a restriction element for auto‐reactive T cells in (NZB×NZW)F1 mice

Mine, K. Miyake, M. Kimoto, 1998, Immunology.

Roles of the Cleaved N-Terminal TLR3 Fragment and Cell Surface TLR3 in Double-Stranded RNA Sensing

K. Miyake, Y. Murakami, S. Saitoh, 2014, The Journal of Immunology.

The Toll-like Receptor Protein Rp105 Regulates Lipopolysaccharide Signaling in B Cells

K. Rajewsky, A. Tarakhovsky, Y. Nagai, 2000, The Journal of experimental medicine.

Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line

D. Schwartz, B. Monks, D. Golenbock, 2001, The Journal of experimental medicine.

TLR accessory molecules.

K. Miyake, Sachiko Akashi-Takamura, 2008, Current opinion in immunology.

Intracellular TLR4/MD-2 in macrophages senses Gram-negative bacteria and induces a unique set of LPS-dependent genes.

K. Miyake, Takuma Shibata, Y. Motoi, 2011, International Immunology.

Reduced Surface Expression of TLR4 by a V254I Point Mutation Accounts for the Low Lipopolysaccharide Responder Phenotype of BALB/c B Cells

Y. Ikeda, H. Tsukamoto, K. Fukudome, 2013, The Journal of Immunology.

Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages.

T. Ichinohe, E. Latz, N. Yoshida, 2021, International immunology.

Emerging roles of the processing of nucleic acids and Toll‐like receptors in innate immune responses to nucleic acids

Toshiyuki Shimizu, K. Miyake, Takuma Shibata, 2017, Journal of leukocyte biology.