M. Okigaki

发表

Dehydroxymethylepoxyquinomicin (DHMEQ) can suppress tumour necrosis factor‐α production in lipopolysaccharide‐injected mice, resulting in rescuing mice from death in vivo

S. Ikehara, K. Umezawa, T. Shimo, 2011, Clinical and experimental immunology.

Mechanism for IL-1 beta-mediated neovascularization unmasked by IL-1 beta knock-out mice.

H. Matsubara, A. Kosaki, S. Fujiyama, 2004, Journal of molecular and cellular cardiology.

Mechanism for IL-1β-mediated Neovascularization Unmasked by IL-1βKnock-out Mice(Molecular Biology, Vascular 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

Y. Mori, H. Matsubara, T. Iwasaka, 2004 .

Src and Pyk2 Mediate G-protein-coupled Receptor Activation of Epidermal Growth Factor Receptor (EGFR) but Are Not Required for Coupling to the Mitogen-activated Protein (MAP) Kinase Signaling Cascade*

J. Schlessinger, S. Logan, O. Kranenburg, 2001, The Journal of Biological Chemistry.

The kinase Pyk2 is involved in renal fibrosis by means of mechanical stretch-induced growth factor expression in renal tubules.

Y. Mori, H. Matsubara, T. Adachi, 2012, Kidney international.

Decreased plasma level of vitamin C in chronic kidney disease: comparison between diabetic and non-diabetic patients.

H. Matsubara, T. Iwasaka, M. Seo, 2011, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Ischemic Hindlimb via Mobilization of Endothelial Progenitor Cells and Rich Water Bathing Enhances Collateral Blood Flow in − Carbon Dioxide

H. Matsubara, M. Okigaki, A. Azuma, 2005 .

Carbon Dioxide–Rich Water Bathing Enhances Collateral Blood Flow in Ischemic Hindlimb via Mobilization of Endothelial Progenitor Cells and Activation of NO-cGMP System

H. Matsubara, M. Okigaki, A. Azuma, 2005, Circulation.

A nuclear factor-κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates GVHD in allogeneic bone marrow transplantation.

S. Ikehara, K. Umezawa, T. Shimo, 2015, Immunobiology.

Novel transcripts of Nox1 are regulated by alternative promoters and expressed under phenotypic modulation of vascular smooth muscle cells.

H. Matsubara, Y. Tabuchi, Noriaki Arakawa, 2006, The Biochemical journal.

Sodium restriction improves the gustatory threshold for salty taste in patients with chronic kidney disease.

Y. Mori, H. Matsubara, T. Adachi, 2009, Kidney international.

Targeted delivery of bone marrow mononuclear cells by ultrasound destruction of microbubbles induces both angiogenesis and arteriogenesis response.

Y. Mori, H. Matsubara, H. Masaki, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Enhancement of Ischemia-Induced Angiogenesis by eNOS Overexpression

H. Matsubara, S. Fujiyama, O. Iba, 2003, Hypertension.

Ultrasound evaluation of valsartan therapy for renal cortical perfusion.

Y. Mori, A. Nose, A. Kosaki, 2004, Hypertension research : official journal of the Japanese Society of Hypertension.

The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets.

M. Falasca, M. Okigaki, S. Kunapuli, 2015, The Biochemical journal.

Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling.

E. Hirsch, E. Ciraolo, M. Falasca, 2012, Blood.

Myocardium-targeted delivery of endothelial progenitor cells by ultrasound-mediated microbubble destruction improves cardiac function via an angiogenic response.

H. Matsubara, M. Okigaki, Y. Adachi, 2006, Journal of molecular and cellular cardiology.

Targeted delivery of bone marrow mononuclear cells by ultrasound destruction of microbubbles induces both angiogenesis and arteriogenesis response.

Y. Mori, H. Matsubara, H. Masaki, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Targeted Delivery of Bone Marrow Mononuclear Cells by Ultrasound Destruction of Microbubbles Induces Both Angiogenesis and Arteriogenesis Response

Y. Mori, H. Matsubara, H. Masaki, 2005 .

p53 and TIGAR regulate cardiac myocyte energy homeostasis under hypoxic stress.

H. Matsubara, M. Okigaki, S. Matoba, 2010, American journal of physiology. Heart and circulatory physiology.

p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia.

H. Matsubara, M. Okigaki, S. Matoba, 2012, Journal of molecular and cellular cardiology.

p53 Promotes Cardiac Dysfunction in Diabetic Mellitus Caused by Excessive Mitochondrial Respiration-Mediated Reactive Oxygen Species Generation and Lipid Accumulation

H. Matsubara, S. Adachi, M. Okigaki, 2012, Circulation. Heart failure.

Switching to an L/N-Type Calcium Channel Blocker Shows Renoprotective Effects in Patients with Chronic Kidney Disease: The Kyoto Cilnidipine Study

Y. Mori, H. Itoh, T. Adachi, 2012, The Journal of international medical research.

Normoalbuminaemia is associated with IgA nephropathy in primary glomerulopathy with nephrotic-range proteinuria in Chinese patients

H. Matsubara, T. Iwasaka, M. Seo, 2011 .

Y. Mori, H. Matsubara, H. Masaki, 2022 .

Increased plasma S100A12 (EN-RAGE) levels in patients with type 2 diabetes.

Y. Mori, H. Matsubara, H. Masaki, 2004, The Journal of clinical endocrinology and metabolism.

The regulation of EN-RAGE (S100A12) gene expression in human THP-1 macrophages.

Y. Mori, H. Matsubara, H. Masaki, 2003, Atherosclerosis.

Macrophages play a unique role in the plaque calcification by enhancing the osteogenic signals exerted by vascular smooth muscle cells.

H. Matsubara, M. Okigaki, H. Yamada, 2012, Biochemical and biophysical research communications.

Efficacy of biventricular pacing for dialysis-related hypotension due to idiopathic dilated cardiomyopathy

H. Matsubara, M. Okigaki, T. Kusaba, 2005, Clinical and Experimental Nephrology.

Replicative senescence of vascular smooth muscle cells enhances the calcification through initiating the osteoblastic transition.

H. Matsubara, M. Okigaki, H. Yamada, 2009, American journal of physiology. Heart and circulatory physiology.

Mucinous tubular and spindle cell carcinoma with a high nuclear grade and micropapillary pattern: A case report

S. Ikehara, J. Watanabe, M. Okigaki, 2017, Molecular and clinical oncology.

Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca2+ channel to maintain endothelial integrity

M. Shibuya, Y. Mori, H. Matsubara, 2010, Proceedings of the National Academy of Sciences.

Endothelium-targeted overexpression of constitutively active FGF receptor induces cardioprotection in mice myocardial infarction.

H. Matsubara, M. Okigaki, Y. Adachi, 2009, Journal of molecular and cellular cardiology.

Neuroprotective Effects of Granulocyte Colony-Stimulating Factor on Ischemia-Reperfusion Injury of the Retina

S. Ikehara, M. Okigaki, Kanji Takahashi, 2012, Ophthalmic Research.

A Case Report of Mycobacterium Abscessus Peritonitis in a Peritoneal Dialysis Patient

Y. Mori, H. Matsubara, T. Adachi, 2007, Therapeutic apheresis and dialysis.

Absence of marginal zone B cells in Pyk-2–deficient mice defines their role in the humoral response

J. Schlessinger, J. Ravetch, M. Okigaki, 2000, Nature Immunology.

Marked Increase in Number of Dendritic Cells in Autoimmune‐Prone (NZW × BXSB)F1 Mice with Age

S. Ikehara, Y. Adachi, M. Okigaki, 2002, Stem cells.

Bone Marrow AT1 Augments Neointima Formation by Promoting Mobilization of Smooth Muscle Progenitors via Platelet-Derived SDF-1&agr;

H. Matsubara, H. Hirai, M. Iwai, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Pressure-Mediated Hypertrophy and Mechanical Stretch Induces IL-1 Release and Subsequent IGF-1 Generation to Maintain Compensative Hypertrophy by Affecting Akt and JNK Pathways

H. Matsubara, D. Riches, M. Okigaki, 2009, Circulation research.

Prorenin induces ERK activation in endothelial cells to enhance neovascularization independently of the renin-angiotensin system.

H. Matsubara, M. Okigaki, H. Yamada, 2009, Biochemical and biophysical research communications.

Bone Marrow Angiotensin AT1 Receptor Regulates Differentiation of Monocyte Lineage Progenitors From Hematopoietic Stem Cells

H. Matsubara, H. Hirai, M. Okigaki, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Β in Receptor Protein Tyrosine Phosphatase No Obvious Abnormality in Mice Deficient

J. Buxbaum, J. Schlessinger, M. Okigaki, 2000 .

Loss of Bcl-2 During the Senescence Exacerbates the Impaired Angiogenic Functions in Endothelial Cells by Deteriorating the Mitochondrial Redox State

H. Matsubara, M. Okigaki, H. Yamada, 2011, Hypertension.

Lack of Three K Mutations of indreds with Preproparathyroid Hormone Familial Isolated Hypoparathy Gene in roidism

M. Okigaki, H. Koshiyama, Toshikazu Yamamoto, 2006 .

Central Role of Calcium-Dependent Tyrosine Kinase PYK2 in Endothelial Nitric Oxide Synthase–Mediated Angiogenic Response and Vascular Function

H. Matsubara, S. Takai, M. Miyazaki, 2007, Circulation.

A Novel Nuclear Factor κB Inhibitor, Dehydroxymethylepoxyquinomicin, Ameliorates Puromycin Aminonucleoside-Induced Nephrosis in Mice

S. Ikehara, K. Umezawa, T. Shimo, 2013, American Journal of Nephrology.

An autopsy case of pulmonary fissure induced by zygomycosis

S. Ikehara, T. Shimo, M. Okigaki, 2013, International Journal of General Medicine.

Akt-Endothelial Nitric Oxide Synthase Activation and Prevent Neointimal Hyperplasia Erythropoietin-Mobilized Endothelial Progenitors Enhance

M. Okigaki, H. Yamada, T. Nomura, 2006 .

Renal involvement in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Y. Mori, M. Nakagawa, K. Sonomura, 2007, Clinical nephrology.

Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration

M. Sheetz, J. Schlessinger, M. Falasca, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Effective treatment of acute theophylline intoxication with both direct hemoperfusion and hemodialysis

H. Matsubara, M. Okigaki, T. Kusaba, 2005 .

Impaired thrombin-induced platelet activation and thrombus formation in mice lacking the Ca(2+)-dependent tyrosine kinase Pyk2.

M. Falasca, M. Okigaki, A. Consonni, 2013, Blood.

Caspase inhibitor ZVAD-fmk facilitates engraftment of donor hematopoietic stem cells in intra-bone marrow-bone marrow transplantation.

T. Yamashima, S. Ikehara, M. Okigaki, 2010, Stem cells and development.

Macrophage Colony‐Stimulating Factor (M‐CSF), As Well As Granulocyte Colony‐Stimulating Factor (G‐CSF), Accelerates Neovascularization

H. Matsubara, T. Iwasaka, M. Matsumura, 2005, Stem cells.

Sarcoid granulomatous interstitial nephritis and sarcoid abdominal aortic aneurysms.

K. Kanda, H. Yaku, M. Okigaki, 2005, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Histamine ameliorates anti-glomerular basement membrane antibody-induced glomerulonephritis in rats.

Y. Mori, K. Sonomura, M. Okigaki, 2007, Kidney international.

Activation of phosphatidylinositol 3-kinase β by the platelet collagen receptors integrin α2β1 and GPVI: The role of Pyk2 and c-Cbl.

E. Hirsch, M. Falasca, M. Okigaki, 2015, Biochimica et biophysica acta.

Involvement of mannose-binding lectin in the pathogenesis of Kawasaki disease-like murine vasculitis.

F. Kametani, M. Okigaki, N. Ohno, 2014, Clinical immunology.

Paracrine Osteogenic Signals via Bone Morphogenetic Protein-2 Accelerate the Atherosclerotic Intimal Calcification In Vivo

H. Matsubara, M. Okigaki, H. Yamada, 2010, Arteriosclerosis, thrombosis, and vascular biology.

The combination method using magnetic beads and a magnet helps sustain the number of donor BM cells after intra-BM injection, resulting in rapid hematopoietic recovery

S. Ikehara, Y. Adachi, M. Okigaki, 2010, Bone Marrow Transplantation.

Nicorandil regulates Bcl-2 family proteins and protects cardiac myocytes against hypoxia-induced apoptosis.

H. Matsubara, M. Okigaki, T. Tatsumi, 2006, Journal of molecular and cellular cardiology.

Role and regulation of phosphatidylinositol 3-kinase (cid:1) in platelet integrin (cid:2) 2 (cid:1) 1 signaling

E. Hirsch, E. Ciraolo, M. Falasca, 2012 .

Apoptosis regulator through modulating IAP expression (ARIA) controls the PI3K/Akt pathway in endothelial and endothelial progenitor cells

H. Matsubara, M. Okigaki, H. Yamada, 2011, Proceedings of the National Academy of Sciences.

Erythropoietin-Mobilized Endothelial Progenitors Enhance Reendothelialization via Akt–Endothelial Nitric Oxide Synthase Activation and Prevent Neointimal Hyperplasia

H. Matsubara, M. Okigaki, H. Yamada, 2006, Circulation research.

Granulocyte Colony-Stimulating Factor–Mobilized Circulating c-Kit+/Flk-1+ Progenitor Cells Regenerate Endothelium and Inhibit Neointimal Hyperplasia After Vascular Injury

H. Matsubara, S. Takai, M. Miyazaki, 2006, Arteriosclerosis, thrombosis, and vascular biology.

A case of CD10-negative angioimmunoblastic T cell lymphoma with leukemic change and increased plasma cells mimicking plasma cell leukemia: A case report.

S. Ikehara, M. Okigaki, Y. Adachi, 2015, Oncology letters.

Histological analysis on adhesive molecules of renal intravascular large B cell lymphoma treated with CHOP chemotherapy and rituximab.

M. Okigaki, T. Kusaba, T. Hatta, 2006, Clinical nephrology.

Endothelial FGF receptor signaling accelerates atherosclerosis.

H. Matsubara, M. Okigaki, H. Yamada, 2011, American journal of physiology. Heart and circulatory physiology.

Distinct Role of Pyk2 in Mediating Thromboxane Generation Downstream of Both G12/13 and Integrin αIIbβ3 in Platelets*

M. Okigaki, S. Kunapuli, Jianguo Jin, 2013, The Journal of Biological Chemistry.

1 DISTINCT ROLE OF PYK 2 IN MEDIATING THROMBOXANE GENERATION DOWNSTREAM OF BOTH G 12 / 13 AND INTEGRIN α IIb β IN PLATELETS *

M. Okigaki, S. Kunapuli, Jianguo Jin, 2013 .

Receptor Tyrosine Kinase

Y. Yoshimasa, M. Okigaki, 2004 .

Signaling from fibroblast growth factor receptor 2 in immature hematopoietic cells facilitates donor hematopoiesis after intra-bone marrow-bone marrow transplantation.

H. Matsubara, S. Ikehara, M. Imamura, 2010, Stem cells and development.

Early Inflammatory Reactions in Atherosclerosis Are Induced by Proline-Rich Tyrosine Kinase/Reactive Oxygen Species–Mediated Release of Tumor Necrosis Factor-&agr; and Subsequent Activation of the p21Cip1/Ets-1/p300 System

Koji Ikeda, Hiroyuki Yamada, H. Matsubara, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Mobilization of bone marrow cells by G-CSF rescues mice from cisplatin-induced renal failure, and M-CSF enhances the effects of G-CSF.

Y. Mori, T. Iwasaka, S. Ikehara, 2005, Journal of the American Society of Nephrology : JASN.

No Obvious Abnormality in Mice Deficient in Receptor Protein Tyrosine Phosphatase β

J. Rosenbluth, J. Buxbaum, J. Schlessinger, 2000, Molecular and Cellular Biology.

Anti-tumor effects of fusion cells of type 1 dendritic cells and Meth A tumor cells using hemagglutinating virus of Japan-envelope.

S. Ikehara, M. Okigaki, Y. Adachi, 2009, International journal of oncology.

Abnormal distribution of dendritic cells in (NZW × BXSB)F1 mice

S. Ikehara, M. Okigaki, Y. Adachi, 2009, Autoimmunity.

Functional characterization of human hepatocyte growth factor mutants obtained by deletion of structural domains.

M. Komada, M. Okigaki, K. Miyazawa, 1992, Biochemistry.

Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor.

M. Okigaki, S. Hirono, K. Miyazawa, 1989, Biochemical and biophysical research communications.

Proteasome inhibitor 1 enhances paclitaxel-induced apoptosis in human lung adenocarcinoma cell line.

S. Ikehara, M. Okigaki, Y. Adachi, 2001, Oncology reports.

p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia.

H. Matsubara, M. Okigaki, S. Matoba, 2012, Journal of Molecular and Cellular Cardiology.

Endothelial FGF receptor signaling accelerates atherosclerosis.

H. Matsubara, M. Okigaki, H. Yamada, 2011, American journal of physiology. Heart and circulatory physiology.

Signaling from fibroblast growth factor receptor 2 in immature hematopoietic cells facilitates donor hematopoiesis after intra-bone marrow-bone marrow transplantation.

H. Matsubara, S. Ikehara, M. Imamura, 2010, Stem cells and development.

Effect of angiotensin II type 2 receptor on tyrosine kinase Pyk2 and c-Jun NH2-terminal kinase via SHP-1 tyrosine phosphatase activity: evidence from vascular-targeted transgenic mice of AT2 receptor.

Y. Mori, H. Matsubara, A. Nose, 2001, Biochemical and biophysical research communications.

Augmentation of Pulse Wave Velocity Precedes Vascular Structural Changes of the Aorta in Rats Treated with N ω-Nitro-L-Arginine Methyl Ester

M. Okigaki, T. Kusaba, H. Narumiya, 2005, Hypertension Research.

Caspase inhibitor ZVAD-fmk facilitates engraftment of donor hematopoietic stem cells in intra-bone marrow-bone marrow transplantation.

T. Yamashima, S. Ikehara, M. Okigaki, 2010, Stem Cells and Development.

Sodium restriction improves the gustatory threshold for salty taste in patients with chronic kidney disease.

Y. Mori, H. Matsubara, T. Adachi, 2009, Kidney international.