J. Bielawski

A. Bielawska, G. Divine, M. Korbelik, 2014, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

Increased killing of SCCVII squamous cell carcinoma cells after the combination of Pc 4 photodynamic therapy and dasatinib is associated with enhanced caspase-3 activity and ceramide synthase 1 upregulation

A. Bielawska, M. Korbelik, P. Breen, 2013, International journal of oncology.

Dihydroceramide desaturase knockdown impacts sphingolipids and apoptosis after photodamage in human head and neck squamous carcinoma cells.

P. Breen, J. Bielawski, G. Bhatti, 2013, Anticancer research.

siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy.

P. Breen, J. Bielawski, T. Gudz, 2012, Anticancer research.

Arabidopsis accelerated cell death 11, ACD11, is a ceramide-1-phosphate transfer protein and intermediary regulator of phytoceramide levels.

A. Bielawska, L. Malinina, D. Patel, 2014, Cell reports.

Positively Charged Ceramide Is a Potent Inducer of Mitochondrial Permeabilization*

Jeffrey A. Jones, A. Bielawska, Y. Hannun, 2005, Journal of Biological Chemistry.

Role for Sit4p‐dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p‐deficient cells

Kellie J. Sims, Y. Hannun, J. Bielawski, 2011, Molecular microbiology.

Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer

H. Grabsch, P. Tan, G. Murray, 2015, BMC Cancer.

Alteration of Ceramide Synthase 6/C16-Ceramide Induces Activating Transcription Factor 6-mediated Endoplasmic Reticulum (ER) Stress and Apoptosis via Perturbation of Cellular Ca2+ and ER/Golgi Membrane Network*

P. Dent, S. Ponnusamy, Marisa Meyers-Needham, 2011, The Journal of Biological Chemistry.

Synthesis, NMR characterization and divergent biological actions of 2'-hydroxy-ceramide/dihydroceramide stereoisomers in MCF7 cells.

A. Bielawska, Y. Hannun, J. Bielawski, 2010, Bioorganic & medicinal chemistry.

Applications and performance of a MALDI-ToF mass spectrometer with quadratic field reflectron technology.

J. Bielawski, Daniel Ivansson, J. Flensburg, 2004, Journal of biochemical and biophysical methods.

Matrix‐assisted laser desorption/ionization: Dependence of the ion yield on the laser beam incidence angle

P. Demirev, M. Karas, B. Sundqvist, 1994 .

Sample exposure effects in matrix-assisted laser desorption—ionization mass spectrometry of large biomolecules

P. Demirev, B. Sundqvist, J. Bielawski, 1994 .

Sphin golipid Ana lysis by Hi gh Per formance Liquid Chromatograp hy-Tan dem Mass Spectrometry (HPLC-MS/MS)

A. Bielawska, J. Bielawski, J. Pierce, 2010 .

Sphingolipid analysis by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).

A. Bielawska, J. Bielawski, J. Pierce, 2010, Advances in experimental medicine and biology.

Neurotoxic 1‐deoxysphingolipids and paclitaxel‐induced peripheral neuropathy

T. Hornemann, D. Ernst, J. Bielawski, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Quantitative measurement of different ceramide species from crude cellular extracts by normal-phase high-performance liquid chromatography coupled to atmospheric pressure ionization mass spectrometry.

Y. Hannun, M. Busman, B. Kroesen, 2004, Rapid communications in mass spectrometry : RCM.

Developmentally Regulated Ceramide Synthase 6 Increases Mitochondrial Ca2+ Loading Capacity and Promotes Apoptosis*

L. Obeid, J. Bielawski, M. Kindy, 2010, The Journal of Biological Chemistry.

Golgi fragmentation is associated with ceramide-induced cellular effects.

Y. Hannun, Wei Hu, L. Obeid, 2005, Molecular biology of the cell.

LCL124, a Cationic Analog of Ceramide, Selectively Induces Pancreatic Cancer Cell Death by Accumulating in Mitochondria

A. Bielawska, P. Lu, B. Ogretmen, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Endothelial Nogo-B regulates sphingolipid biosynthesis to promote pathological cardiac hypertrophy during chronic pressure overload.

J. Bielawski, Yan Huang, A. Di Lorenzo, 2016, JCI insight.

Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity[S]

Wei Hu, A. Merrill, J. Bielawski, 2009, Journal of Lipid Research.

Fatty acids differentially regulate insulin resistance through endoplasm reticulum stress-mediated induction of tribbles homologue 3: a potential link between dietary fat composition and the pathophysiological outcomes of obesity

J. Schwacke, J. Bielawski, T. Geng, 2013, Diabetologia.

Ceramide and Ceramide 1-Phosphate Are Negative Regulators of TNF-α Production Induced by Lipopolysaccharide

A. Bielawska, Maciej Czerkies, S. Jozefowski, 2010, The Journal of Immunology.

Synthesis of erythro- B13 enantiomers and stereospecific action of full set of B13-isomers in MCF7 breast carcinoma cells: Cellular metabolism and effects on sphingolipids.

A. Bielawska, Y. Hannun, J. Bielawski, 2021, Bioorganic & medicinal chemistry.

Bioactive sphingolipid profile in a xenograft mouse model of head and neck squamous cell carcinoma

Y. Hannun, J. Bielawski, Xiang Liu, 2019, PloS one.

Ceramide Generated by Sphingomyelin Hydrolysis and the Salvage Pathway Is Involved in Hypoxia/Reoxygenation-induced Bax Redistribution to Mitochondria in NT-2 Cells*

A. Bielawska, Y. Hannun, L. Obeid, 2008, Journal of Biological Chemistry.

Protein Kinase C-induced Activation of a Ceramide/Protein Phosphatase 1 Pathway Leading to Dephosphorylation of p38 MAPK*

Y. Hannun, L. Obeid, C. Senkal, 2006, Journal of Biological Chemistry.

Neutral Ceramidase Encoded by the Asah2 Gene Is Essential for the Intestinal Degradation of Sphingolipids*

A. Bielawska, Y. Hannun, R. Proia, 2006, Journal of Biological Chemistry.

Altered Adipose and Plasma Sphingolipid Metabolism in Obesity

Y. Hannun, J. Bielawski, Guang Yang, 2006, Diabetes.

Alkaline Ceramidase 3 (ACER3) Hydrolyzes Unsaturated Long-chain Ceramides, and Its Down-regulation Inhibits Both Cell Proliferation and Apoptosis*

Wei Hu, L. Obeid, J. Bielawski, 2010, The Journal of Biological Chemistry.

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes.

Wei Hu, L. Obeid, J. Bielawski, 2008, The Journal of investigative dermatology.

Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P

Wei Hu, L. Obeid, J. Bielawski, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Plasma Sphingolipids and Lung Cancer: A Population-Based, Nested Case–Control Study

A. Bielawska, A. Alberg, E. Hill, 2013, Cancer Epidemiology, Biomarkers & Prevention.

Dihydrosphingosine 1‐phosphate stimulates MMP1 gene expression via activation of ERK1/2‐Ets1 pathway in human fibroblasts

A. Bielawska, Y. Hannun, L. Obeid, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Role of 1‐Deoxysphingolipids in docetaxel neurotoxicity

B. Taylor, E. Gulbins, U. Sure, 2020, Journal of neurochemistry.

Ectopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiency

K. Gable, T. Dunn, J. Bielawski, 2016, Proceedings of the National Academy of Sciences.

Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells.

S. Jazwinski, J. Bielawski, David X. Liu, 2014, Biochimica et biophysica acta.

Mitochondrially targeted ceramide LCL-30 inhibits colorectal cancer in mice

A. Bielawska, Y. Hannun, W. Jochum, 2007, British Journal of Cancer.

Distribution and dynamic changes of sphingolipids in blood in response to platelet activation

A. Bielawska, Y. Hannun, J. Bielawski, 2006, Journal of thrombosis and haemostasis : JTH.

Tailoring structure-function and targeting properties of ceramides by site-specific cationization.

A. Bielawska, Y. Hannun, L. Obeid, 2006, Bioorganic & medicinal chemistry.

Involvement of sphingolipids in apoptin-induced cell killing.

A. Bielawska, Y. Hannun, J. Bielawski, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

Lysosomotropic acid ceramidase inhibitor induces apoptosis in prostate cancer cells

A. Bielawska, Y. Hannun, J. Bielawski, 2007, Cancer Chemotherapy and Pharmacology.

Ceramide channels: influence of molecular structure on channel formation in membranes.

A. Bielawska, J. Bielawski, R. Bittman, 2012, Biochimica et biophysica acta.

Modulation of ceramide metabolism enhances viral protein apoptin's cytotoxicity in prostate cancer.

Y. Hannun, J. Bielawski, A. El-Zawahry, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

Sphingomyelinase‐like phosphodiesterase 3b mediates radiation‐induced damage of renal podocytes

B. Marples, A. Fornoni, J. Bielawski, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Stress-Induced Sphingolipid Signaling: Role of Type-2 Neutral Sphingomyelinase in Murine Cell Apoptosis and Proliferation

Y. Hannun, A. Nègre-Salvayre, J. Guénet, 2010, PloS one.

Involvement of sphingoid bases in mediating reactive oxygen intermediate production and programmed cell death in Arabidopsis

Y. Hannun, J. Mu, Jian Zhang, 2007, Cell Research.

Regulation of the sphingosine-recycling pathway for ceramide generation by oxidative stress, and its role in controlling c-Myc/Max function.

A. Bielawska, Y. Hannun, S. Ponnusamy, 2006, The Biochemical journal.

Tumor Necrosis Factor Induces the Loss of Sphingosine Kinase-1 by a Cathepsin B-dependent Mechanism*

Y. Hannun, L. Obeid, J. Bielawski, 2005, Journal of Biological Chemistry.

Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide

Y. Hannun, F. Platt, J. Bielawski, 2007, Nature.

Cloning and Characterization of a Mouse Endoplasmic Reticulum Alkaline Ceramidase

A. Bielawska, Wei Hu, L. Obeid, 2003, Journal of Biological Chemistry.

Roles for C 16-ceramide and Sphingosine 1-Phosphate in Regulating Hepatocyte Apoptosis in Response to Tumor Necrosis Factor-* □

R. Schwabe, D. Brenner, Y. Hannun, 2005 .

Synthesis and bioevaluation of omega-N-amino analogs of B13.

A. Bielawska, Y. Hannun, J. Bielawski, 2009, Bioorganic & medicinal chemistry.

Targeting glucosylceramide synthase sensitizes imatinib-resistant chronic myeloid leukemia cells via endogenous ceramide accumulation

B. Ogretmen, J. Bielawski, Y. Baran, 2011, Journal of Cancer Research and Clinical Oncology.

Comprehensive quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry.

A. Bielawska, J. Bielawski, J. Pierce, 2009, Methods in molecular biology.

Phosphorylating intermediates in the peracid oxidation of phosphorothionates, phosphorothiolates, and phosphorodithioates

J. Casida, J. Bielawski, 1988 .

phosphate and ceramide-1-phosphate

Y. Hannun, L. Obeid, C. Chalfant, 2005 .

Sphingosine kinase 1 expression enhances colon tumor growth

H. Furuya, J. Bielawski, I. Pagano, 2017, Journal of Translational Medicine.

A Role of Sphingosine Kinase 1 in head & neck carcinogenesis

Y. Hannun, L. Obeid, B. Ogretmen, 2010 .

The sphingosine kinase 1/sphingosine-1-phosphate pathway mediates COX-2 induction and PGE2 production in response to TNF-alpha.

Korey R. Johnson, Y. Hannun, J. Morrow, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

C16-Ceramide Analog Combined with Pc 4 Photodynamic Therapy Evokes Enhanced Total Ceramide Accumulation, Promotion of DEVDase Activation in the Absence of Apoptosis, and Augmented Overall Cell Killing

A. Bielawska, J. Bielawski, J. Pierce, 2010, Journal of lipids.

N‐Vinyl as N‐H protecting group. Synthesis of cyclic imines from N‐vinyllactams and organolithium reagents

J. Bielawski, L. Lindblom, S. Brandänge, 1978 .

NEW PESTICIDES AND INTERMEDIATES. PART VIII. QUATERNARY AMMONIUM SALTS OF AZACYCLIC DERIVATIVES

A. Bielawska, J. Bielawski, S. Witek, 1983 .

Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry.

A. Bielawska, Y. Hannun, J. Bielawski, 2006, Methods.

The Human FA2H Gene Encodes a Fatty Acid 2-Hydroxylase*

A. Bielawska, J. Bielawski, N. L. Alderson, 2004, Journal of Biological Chemistry.

Elevation of 20-carbon long chain bases due to a mutation in serine palmitoyltransferase small subunit b results in neurodegeneration

Sita D Gupta, K. Gable, T. Dunn, 2015, Proceedings of the National Academy of Sciences.

Cell density-dependent reduction of dihydroceramide desaturase activity in neuroblastoma cells[S]

L. Obeid, J. Bielawski, C. Clarke, 2012, Journal of Lipid Research.

Ceramide Synthase-dependent Ceramide Generation and Programmed Cell Death

Y. Hannun, L. Obeid, J. Bielawski, 2011, The Journal of Biological Chemistry.

Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism[S]

Y. Hannun, L. Obeid, J. Bielawski, 2011, Journal of Lipid Research.

Substrate Specificity, Membrane Topology, and Activity Regulation of Human Alkaline Ceramidase 2 (ACER2)*

Wei Hu, L. Obeid, J. Bielawski, 2010, The Journal of Biological Chemistry.

Necessary Role for the Lag1p Motif in (Dihydro)ceramide Synthase Activity*

Y. Hannun, L. Obeid, S. Jazwinski, 2006, Journal of Biological Chemistry.

Novel Pathway of Ceramide Production in Mitochondria

Y. Hannun, L. Obeid, J. Bielawski, 2011, The Journal of Biological Chemistry.

Molecular cloning and characterization of OsCDase, a ceramidase enzyme from rice.

Y. Hannun, J. Bielawski, Bill X. Wu, 2008, The Plant journal : for cell and molecular biology.

Alterations of Ceramide/Sphingosine 1-Phosphate Rheostat Involved in the Regulation of Resistance to Imatinib-induced Apoptosis in K562 Human Chronic Myeloid Leukemia Cells*

L. Obeid, C. Senkal, Arelis Salas, 2007, Journal of Biological Chemistry.

Roles for C16-ceramide and Sphingosine 1-Phosphate in Regulating Hepatocyte Apoptosis in Response to Tumor Necrosis Factor-α*

R. Schwabe, D. Brenner, Y. Hannun, 2005, Journal of Biological Chemistry.

Dose dependent actions of LCL521 on acid ceramidase and key sphingolipid metabolites.

A. Bielawska, Y. Hannun, J. Bielawski, 2018, Bioorganic & medicinal chemistry.

The functional effects of acid ceramidase over-expression in prostate cancer progression and resistance to chemotherapy

A. Bielawska, Y. Hannun, L. Obeid, 2007, Cancer biology & therapy.

Targeting (cellular) lysosomal acid ceramidase by B13: design, synthesis and evaluation of novel DMG-B13 ester prodrugs.

A. Bielawska, Y. Hannun, J. Bielawski, 2014, Bioorganic & medicinal chemistry.

Novel analogs of D-e-MAPP and B13. Part 1: synthesis and evaluation as potential anticancer agents.

A. Bielawska, Y. Hannun, J. Bielawski, 2008, Bioorganic & medicinal chemistry.

Novel analogs of D-e-MAPP and B13. Part 2: signature effects on bioactive sphingolipids.

A. Bielawska, Y. Hannun, J. Bielawski, 2008, Bioorganic & medicinal chemistry.

Involvement of Dihydroceramide Desaturase in Cell Cycle Progression in Human Neuroblastoma Cells*

A. Bielawska, Y. Hannun, L. Obeid, 2007, Journal of Biological Chemistry.

Combination of C(17) sphingoid base homologues and mass spectrometry analysis as a new approach to study sphingolipid metabolism.

L. Obeid, J. Bielawski, V. Anelli, 2007, Methods in enzymology.

Role for Mammalian Neutral Sphingomyelinase 2 in Confluence-induced Growth Arrest of MCF7 Cells*

Jacek Bielawski, Yusuf A. Hannun, Y. Hannun, 2004, Journal of Biological Chemistry.

Some New Organoboron-Nitrogen Heterocycles

J. Bielawski, K. Niedenzu, 1980 .

1,10,11,9-Triazaborabicyclo[4.5.0] nonane1

J. Bielawski, K. Niedenzu, 1979 .

Acid ceramidase inhibition: a novel target for cancer therapy.

A. Bielawska, Y. Hannun, J. Bielawski, 2008, Frontiers in bioscience : a journal and virtual library.

The CLN9 Protein, a Regulator of Dihydroceramide Synthase*

A. Bielawska, G. Dbaibo, S. Jazwinski, 2006, Journal of Biological Chemistry.

Role for sphingosine kinase 1 in colon carcinogenesis

Y. Hannun, L. Obeid, J. Bielawski, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Impairment of ceramide synthesis causes a novel progressive myoclonus epilepsy

P. Striano, P. Bramanti, F. Zara, 2014, Annals of neurology.

Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression

L. Del Valle, Z. Qin, Charles D Smith, 2015, Oncotarget.

Maternal disturbance in activated sphingolipid metabolism causes pregnancy loss in mice.

A. Bielawska, C. Deng, R. Proia, 2007, The Journal of clinical investigation.

Functional antagonism of sphingosine‐1‐phosphate receptor 1 prevents cuprizone‐induced demyelination

Jianrong Li, Beiyan Zhou, J. Bielawski, 2018, Glia.

Involvement of endogenous ceramide in the inhibition of telomerase activity and induction of morphologic differentiation in response to all-trans-retinoic acid in human neuroblastoma cells.

L. Obeid, B. Ogretmen, J. Bielawski, 2003, Archives of biochemistry and biophysics.

Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis

Y. Peterson, D. Perrotti, E. Garrett-Mayer, 2012, EMBO molecular medicine.

Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury

A. Bielawska, Y. Hannun, L. Obeid, 2017, Journal of Lipid Research.

Potent Antitumor Activity of a Novel Cationic Pyridinium-Ceramide Alone or in Combination with Gemcitabine against Human Head and Neck Squamous Cell Carcinomas in Vitro and in Vivo

A. Bielawska, Y. Hannun, D. Sinha, 2006, Journal of Pharmacology and Experimental Therapeutics.

Potent Anti-Tumor Activity of a Novel Cationic Pyridinium-Ceramide Alone or In Combination with Gemcitabine Against Human Head and Neck Squamous Cell Carcinomas In vitro and In vivo

A. Bielawska, Y. Hannun, D. Sinha, 2006 .

Isc1 regulates sphingolipid metabolism in yeast mitochondria.

Y. Hannun, L. Obeid, J. Bielawski, 2007, Biochimica et biophysica acta.

Sphingosine Kinase 1 (SPHK1) Is Induced by Transforming Growth Factor-β and Mediates TIMP-1 Up-regulation*

A. Bielawska, Y. Hannun, L. Obeid, 2004, Journal of Biological Chemistry.

[Effect of physiologic and instrumental labor on the hormonal activity of the hypothalamo-hypophyseo-thyroid system. I. Physiologic labor].

B. Jarzab, J. Bielawski, L. Dzieciuchowicz, 1988, Ginekologia polska.

PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells.

M. Caligiuri, J. Byrd, C. Croce, 2013, The Journal of clinical investigation.

Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome.

Jacek Bielawski, Y. Hannun, A. Roberts, 2009, American journal of physiology. Endocrinology and metabolism.

Membrane sphingolipids as essential molecular signals for Bacteroides survival in the intestine

Y. Hannun, J. Bielawski, D. Kasper, 2010, Proceedings of the National Academy of Sciences.

Down-regulation of Sphingosine Kinase-1 by DNA Damage

Korey R. Johnson, Y. Hannun, W. Gillanders, 2004, Journal of Biological Chemistry.

Regulation of Telomere Length by Fatty Acid Elongase 3 in Yeast

S. Snyder, S. Jazwinski, S. Ponnusamy, 2008, Journal of Biological Chemistry.

Dietary glucosylceramides suppress tumor growth in a mouse xenograft model of head and neck squamous cell carcinoma by the inhibition of angiogenesis through an increase in ceramide

A. Bielawska, J. Bielawski, K. Fujiwara, 2015, International Journal of Clinical Oncology.

De novo N-palmitoylsphingosine synthesis is the major biochemical mechanism of ceramide accumulation following p53 up-regulation.

A. Bielawska, Y. Hannun, G. Dbaibo, 2008, Prostaglandins & other lipid mediators.

Cytokine-induced release of ceramide-enriched exosomes as a mediator of cell death signaling in an oligodendroglioma cell line[S]

A. Bielawska, N. Bhat, E. Hogan, 2016, Journal of Lipid Research.

Lipidomic profiling in Crohn's disease: Abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition

Xianlin Han, Y. Hannun, R. Vega, 2012, The international journal of biochemistry & cell biology.

Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression

A. Bielawska, Xia Li, Dafeng Yang, 2014, BMC Cancer.

Synthesis and bioevaluation of ω -N-amino analogs of B13

A. Bielawska, Y. Hannun, J. Bielawski, 2009 .

Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C(18)-ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis.

Y. Hannun, D. Sinha, M. B. Gillespie, 2007, Cancer letters.

Sphingomyelin Synthase 1-generated Sphingomyelin Plays an Important Role in Transferrin Trafficking and Cell Proliferation*

A. Bielawska, Y. Igarashi, Ken Watanabe, 2011, The Journal of Biological Chemistry.

Suppression of sphingomyelin synthase 1 by small interference RNA is associated with enhanced ceramide production and apoptosis after photodamage.

A. Tarca, J. Bielawski, K. Hanada, 2008, Experimental cell research.

Increased Plasma Levels of Select Deoxy-ceramide and Ceramide Species are Associated with Increased Odds of Diabetic Neuropathy in Type 1 Diabetes: A Pilot Study

N. Baker, J. Bielawski, R. Klein, 2017, NeuroMolecular Medicine.

Protection from High Fat Diet-induced Increase in Ceramide in Mice Lacking Plasminogen Activator Inhibitor 1*

Y. Hannun, J. Bielawski, Guang Yang, 2008, Journal of Biological Chemistry.

Sphingolipid Pathway Regulates Innate Immune Responses at the Fetomaternal Interface during Pregnancy*

I. Konishi, H. Hatayama, J. Bielawski, 2014, The Journal of Biological Chemistry.

Activation of sphingosine‐1‐phosphate receptor S1P5 inhibits oligodendrocyte progenitor migration

L. Obeid, J. Bielawski, T. Gudz, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Altered Levels of Serum Ceramide, Sphingosine and Sphingomyelin Are Associated with Colorectal Cancer: A Retrospective Pilot Study.

A. Bielawska, P. Philip, A. Shields, 2017, Anticancer research.

Boron-nitrogen compounds. 111. Reactions of borazines with pyrazole and related studies: (.mu.-amido)(.mu.-pyrazolato)diboron species, novel relatives of the pyrazaboles

J. Bielawski, M. K. Das, H. Noeth, 1986 .

Chemistry of Boron. Part 178. Boron‐Nitrogen Compounds. Part 111. Reactions of Borazines with Pyrazole and Related Studies: (μ‐Amido)(μ‐pyrazolato)diboron Species, Novel Relatives of the Pyrazaboles.

J. Bielawski, M. K. Das, H. Noeth, 1987 .

Role of Human Sphingosine-1-phosphate Phosphatase 1 in the Regulation of Intra- and Extracellular Sphingosine-1-phosphate Levels and Cell Viability*

Korey R. Johnson, L. Obeid, J. Bielawski, 2003, Journal of Biological Chemistry.

Increased ceramide accumulation correlates with downregulation of the autophagy protein ATG‐7 in MCF‐7 cells sensitized to photodamage

A. Tarca, J. Bielawski, A. Kelekar, 2010, Archives of biochemistry and biophysics.

Downregulation of the autophagy protein ATG-7 correlates with distinct sphingolipid profile in MCF-7 cells sensitized to photodamage

David Kessel, Duska Separovic, Ameeta Kelekar, 2009, World Congress of the International Photodynamic Association.

C6-pyridinium ceramide sensitizes SCC17B human head and neck squamous cell carcinoma cells to photodynamic therapy.

A. Bielawska, M. Korbelik, J. Bielawski, 2015, Journal of Photochemistry and Photobiology. B: Biology.

Fumonisin B1 Inhibits Endoplasmic Reticulum Stress Associated-apoptosis After FoscanPDT Combined with C6-Pyridinium Ceramide or Fenretinide.

A. Bielawska, M. Korbelik, J. Bielawski, 2017, Anticancer research.

Increased tumour dihydroceramide production after Photofrin-PDT alone and improved tumour response after the combination with the ceramide analogue LCL29. Evidence from mouse squamous cell carcinomas

M. Korbelik, B. Ogretmen, A. Tarca, 2009, British Journal of Cancer.

A Role of Sphingosine Kinase 1 in Head and Neck Carcinogenesis

Y. Hannun, L. Obeid, B. Ogretmen, 2011, Cancer Prevention Research.

Cyclic Boron Derivatives of Biurets [1]

J. Bielawski, K. Niedenzu, W. Weber, 1981 .

BORON-NITROGEN COMPOUNDS. PART 93. CYCLIC BORON DERIVATIVES OF BIURETS

J. Bielawski, K. Niedenzu, W. Weber, 1981 .

Sphingosine kinase 1 expression enhances colon tumor growth

H. Furuya, J. Bielawski, I. Pagano, 2017, Journal of Translational Medicine.

Ceramide and Sphingosine-1-Phosphate/Sphingosine act as Photodynamic Therapy-Elicited Damage-Associated Molecular Patterns: Release from Cells and Impact on Tumor-Associated Macrophages

Wei Zhang, M. Korbelik, J. Bielawski, 2014 .

Combining anticancer agents photodynamic therapy and LCL85 leads to distinct changes in the sphingolipid profile, autophagy, caspase-3 activation in the absence of cell death, and long-term sensitization.

A. Bielawska, P. Breen, J. Bielawski, 2011, Biochemical and biophysical research communications.

Synthetic triterpenoids have cytotoxicity in pediatric acute lymphoblastic leukemia cell lines but cytotoxicity is independent of induced ceramide increase in MOLT-4 cells

M. Konopleva, M. Andreeff, J. Bielawski, 2008, Leukemia.

Cloning and Characterization of a Mouse Endoplasmic Reticulum Alkaline Ceramidase AN ENZYME THAT PREFERENTIALLY REGULATES METABOLISM OF VERY LONG CHAIN CERAMIDES*

A. Bielawska, L. Obeid, J. Bielawski, 2003 .

Triply bridged diboron species of the pyrazabole type

J. Bielawski, K. Niedenzu, 1986 .

Central nervous system dysfunction in a mouse model of Fa2h deficiency

Xianlin Han, S. Scherer, S. Yum, 2011, Glia.

Alteration of Ceramide Synthase 6/C 16 -Ceramide Induces Activating Transcription Factor 6-mediated Endoplasmic Reticulum (ER) Stress and Apoptosis via Perturbation of

P. Dent, S. Ponnusamy, Marisa Meyers-Needham, 2011 .

Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity[S]

Wei Hu, J. Bielawski, F. Samad, 2009, Journal of Lipid Research.

Novel Pathway of Ceramide Production in Mitochondria

Y. Hannun, L. Obeid, J. Bielawski, 2011, The Journal of Biological Chemistry.

Protection from High Fat Diet-induced Increase in Ceramide in Mice Lacking Plasminogen Activator Inhibitor 1*

Y. Hannun, J. Bielawski, Guang Yang, 2008, Journal of Biological Chemistry.

Sphingosine kinase 1 regulates adipose proinflammatory responses and insulin resistance.

T. Ciaraldi, J. Bielawski, Leylla Badeanlou, 2014, American journal of physiology. Endocrinology and metabolism.

Modulation of total ceramide and constituent ceramide species in the acutely and chronically hypoxic mouse heart at different ages.

G. Dbaibo, J. Bielawski, G. Nemer, 2008, Prostaglandins & other lipid mediators.

Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression

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AMPK inhibitor Compound C stimulates ceramide production and promotes Bax redistribution and apoptosis in MCF7 breast carcinoma cells

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