G. Kaufmann

发表

Modulation of Gene Expression via Disruption of NF-κB Signaling by a Bacterial Small Molecule

Michael M. Meijler, Kim D. Janda, K. Janda, 2008, Science.

Infection control by antibody disruption of bacterial quorum sensing signaling.

Junguk Park, Kim D Janda, Michael M Meijler, 2007, Chemistry & biology.

PSMA-targeted bispecific Fab conjugates that engage T cells.

G. Kaufmann, R. Duggal, D. Bresson, 2017, Bioorganic & medicinal chemistry letters.

Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity.

J. Sundberg, P. Stranges, Austin C. Stonebraker, 2007, Immunity.

A method for the generation of combinatorial antibody libraries using pIX phage display

Kim D Janda, Richard A Lerner, R. Lerner, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Targeting Heat-Shock Protein 90 (HSP90) as a Complementary Strategy to Immune Checkpoint Blockade for Cancer Therapy

D. Proia, G. Kaufmann, 2015, Cancer Immunology Research.

A Novel Affinity Engineered Anti-CD47 Antibody With Improved Therapeutic Index That Preserves Erythrocytes and Normal Immune Cells

G. Kaufmann, D. Bresson, B. Swanson, 2022, Frontiers in Oncology.

Fluorescent cocaine probes: a tool for the selection and engineering of therapeutic antibodies.

M. Matsushita, P. Wirsching, K. Janda, 2005, Journal of the American Chemical Society.

Toward cocaine esterase therapeutics.

K. Janda, G. Kaufmann, T. Dickerson, 2005, Journal of the American Chemical Society.

N-(3-Oxo-acyl)homoserine Lactones Signal Cell Activation through a Mechanism distinct from the Canonical Pathogen-associated Molecular Pattern Recognition Receptor Pathways*

K. Janda, C. Fearns, R. Ulevitch, 2006, Journal of Biological Chemistry.

Exploitation of host signaling pathways by microbial quorum sensing signals.

K. Rumbaugh, G. Kaufmann, 2012, Current opinion in microbiology.

Stereochemical Insignificance Discovered in Acinetobacter baumannii Quorum Sensing

K. Janda, G. Kaufmann, Jie-ping Zhu, 2012, PloS one.

Generation of quorum quenching antibodies.

K. Janda, G. Kaufmann, Diane M Kubitz, 2011, Methods in molecular biology.

Repositioning of an existing drug for the neglected tropical disease Onchocerciasis

Amanda L. Garner, Kim D. Janda, K. Janda, 2010, Proceedings of the National Academy of Sciences.

Identification and characterization of single chain anti-cocaine catalytic antibodies.

K. Janda, G. Kaufmann, K. M. McKenzie, 2007, Journal of molecular biology.

Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1.

Y. Liu, Bin Zhou, K. Janda, 2010, Molecular pharmaceutics.

Chemically generated IgG2 bispecific antibodies through disulfide bridging.

G. Kaufmann, Edwige Gros, Bryan E. Jones, 2017, Bioorganic & medicinal chemistry letters.

Glycation Reactivity of a Quorum-Sensing Signaling Molecule.

K. Janda, G. Kaufmann, Jie-ping Zhu, 2016, Angewandte Chemie.

The Anti-ROR1 Monoclonal Antibody Zilovertamab Inhibits the Proliferation of Ovarian and Endometrial Cancer Cells

D. Marsh, C. Ford, G. Kaufmann, 2022, Pharmaceutics.

Defining the mode of action of tetramic acid antibacterials derived from Pseudomonas aeruginosa quorum sensing signals.

Ryan S. Mueller, R. Ulrich, K. Janda, 2009, Journal of the American Chemical Society.

Antibody interference with N-acyl homoserine lactone-mediated bacterial quorum sensing.

K. Janda, G. Kaufmann, M. Meijler, 2006, Journal of the American Chemical Society.

Deeply Inverted Electron-Hole Recombination in a Luminescent Antibody-Stilbene Complex

R. Lerner, P. Schultz, I. Wilson, 2008, Science.

Enzymatic incorporation of an antibody-activated blue fluorophore into DNA.

R. Lerner, T. Z. Hoffman, P. Wirsching, 2005, Angewandte Chemie.

Functional role of asparaginyl endopeptidase ubiquitination by TRAF6 in tumor invasion and metastasis.

X. Chen, Zhimin Lu, G. Kaufmann, 2014, Journal of the National Cancer Institute.

Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery.

Y. Liu, K. Janda, G. Kaufmann, 2007, Molecular pharmaceutics.

Bacterial inhibition of inflammatory responses via TLR‐independent mechanisms

V. Kravchenko, G. Kaufmann, 2013, Cellular microbiology.

Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand.

Ying Liu, Kim D Janda, Bin Zhou, 2006, Biochemistry.

Bacterial quorum sensing: a new target for anti-infective immunotherapy

K. Janda, G. Kaufmann, Junguk Park, 2008, Expert opinion on biological therapy.

The use of small molecule probes to study spatially separated stimulus-induced signaling pathways.

K. Janda, R. Ulevitch, V. Kravchenko, 2012, Bioorganic & medicinal chemistry letters.

Toward implementation of quorum sensing autoinducers as biomarkers for infectious disease states.

K. Janda, D. Conrad, G. Kaufmann, 2013, Analytical chemistry.

Medicinal chemistry as a conduit for the modulation of quorum sensing.

K. Janda, G. Kaufmann, D. Sawada, 2010, Journal of medicinal chemistry.

Treating cocaine addiction with viruses.

G. Koob, K. Janda, G. Kaufmann, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Revisiting AI-2 quorum sensing inhibitors: direct comparison of alkyl-DPD analogues and a natural product fimbrolide.

K. Janda, G. Kaufmann, Takumi Abe, 2009, Journal of the American Chemical Society.

Macromolecular inhibition of quorum sensing: enzymes, antibodies, and beyond.

G. Kaufmann, M. Meijler, B. P. Krom, 2011, Chemical reviews.

Revisiting quorum sensing: Discovery of additional chemical and biological functions for 3-oxo-N-acylhomoserine lactones.

Tobin J Dickerson, Kim D Janda, Bruce Clapham, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structures of a quorum-quenching antibody.

I. Wilson, E. Debler, K. Janda, 2007, Journal of molecular biology.

A cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy.

Ying Liu, Kim D Janda, Y. Liu, 2008, Bioorganic & medicinal chemistry letters.

Immunoediting role for major vault protein in apoptotic signaling induced by bacterial N-acyl homoserine lactones

V. Kickhoefer, L. Rome, H. Overkleeft, 2021, Proceedings of the National Academy of Sciences.

Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.

I. Wilson, K. Janda, G. Kaufmann, 2006, Structure.

Quo vadis quorum quenching?

G. Kaufmann, Jie-ping Zhu, 2013, Current opinion in pharmacology.

A chemical biology approach to interrogate quorum-sensing regulated behaviors at the molecular and cellular level.

Samuel I. Miller, Sherry L. Niessen, B. Cravatt, 2013, Chemistry & biology.

Discovering Additional Chemical and Biological Functions for 3-Oxo-N-Acylhomoserine Lactones

K. Janda, G. Kaufmann, M. Meijler, 2006 .

Solenopsin A, a venom alkaloid from the fire ant Solenopsis invicta, inhibits quorum-sensing signaling in Pseudomonas aeruginosa.

J. Arbiser, K. Janda, J. P. Bowen, 2008, The Journal of infectious diseases.

The quorum quenching antibody RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone.

K. Janda, R. Ulevitch, G. Kaufmann, 2008, Molecular immunology.

C4-alkoxy-HPD: a potent class of synthetic modulators surpassing nature in AI-2 quorum sensing.

K. Janda, G. Kaufmann, Jie-ping Zhu, 2012, Journal of the American Chemical Society.

A multivalent probe for AI-2 quorum-sensing receptors.

K. Janda, G. Kaufmann, D. Sawada, 2011, Journal of the American Chemical Society.

Challenges in αCD38-chimeric antigen receptor (CAR)-expressing natural killer (NK) cell-based immunotherapy in multiple myeloma: Harnessing the CD38dim phenotype of cytokine-stimulated NK cells as a strategy to prevent fratricide.

H. Ljunggren, E. Alici, G. Kaufmann, 2023, Cytotherapy.

Immunomodulation and the quorum sensing molecule 3-oxo-C12-homoserine lactone: the importance of chemical scaffolding for probe development.

K. Janda, V. Kravchenko, G. Kaufmann, 2013, Chemical communications.

Modulation of mammalian cell processes by bacterial quorum sensing molecules.

R. Ulevitch, V. Kravchenko, G. Kaufmann, 2011, Methods in molecular biology.

Phage-display selection of a human single-chain fv antibody highly specific for melanoma and breast cancer cells using a chemoenzymatically synthesized G(M3)-carbohydrate antigen.

James Paulson, Kim D Janda, Ola Blixt, 2002, Journal of the American Chemical Society.

Bacteriophage-mediated protein delivery into the central nervous system and its application in immunopharmacotherapy

Tobin J Dickerson, Kim D Janda, K. Janda, 2005, Expert opinion on biological therapy.

Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody*

I. Wilson, K. Janda, G. Kaufmann, 2011, The Journal of Biological Chemistry.

Synthesis of 'clickable' acylhomoserine lactone quorum sensing probes: unanticipated effects on mammalian cell activation.

K. Janda, V. Kravchenko, G. Kaufmann, 2011, Bioorganic & medicinal chemistry letters.

Determination of acyl homoserine lactone and tetramic acid concentrations in biological samples.

K. Janda, G. Kaufmann, Colin A. Lowery, 2011, Methods in molecular biology.

Synthesis and biological validation of a ubiquitous quorum-sensing molecule.

Kim D Janda, Michael M Meijler, M. Matsushita, 2004, Angewandte Chemie.

Retraction: Stereochemical Insignificance Discovered in Acinetobacter baumannii Quorum Sensing

K. Janda, G. Kaufmann, Jie-ping Zhu, 2013, PloS one.

Genetic Determinants of Self Identity and Social Recognition in Bacteria

E. Greenberg, M. Urbanowski, K. Janda, 2008, Science.

Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody*

I. Wilson, K. Janda, G. Kaufmann, 2011, The Journal of Biological Chemistry.

Mechanistic insights into the LsrK kinase required for autoinducer-2 quorum sensing activation.

Kim D Janda, K. Janda, G. Kaufmann, 2013, Journal of the American Chemical Society.

An unexpected switch in the modulation of AI-2-based quorum sensing discovered through synthetic 4,5-dihydroxy-2,3-pentanedione analogues.

Junguk Park, Kim D. Janda, K. Janda, 2008, Journal of the American Chemical Society.