P. V. van Leeuwen

发表

The role of Kupffer cells after major liver surgery.

H. Prins, C. Meijer, P. G. Boelens, 2005, JPEN. Journal of parenteral and enteral nutrition.

Potential applications of N-terminal recombinant fragments of bactericidal/permeability-increasing protein in liver surgery.

S. Meijer, H. Prins, C. Meijer, 1999, Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

Flavonoids: a review of probable mechanisms of action and potential applications.

E. van Nood, P. G. Boelens, P. V. van Leeuwen, 2001, The American journal of clinical nutrition.

Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T‐lymphocytes and preserved MHC class I antigen expression

Erik Hooijberg, T. D. de Gruijl, P. V. van Leeuwen, 2008, International journal of cancer.

The transplanted liver graft is capable of clearing asymmetric dimethylarginine

E. Kuipers, D. Kuik, S. Meijer, 2004, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

KUPFFER CELL–DEPLETED RATS HAVE A DIMINISHED ACUTE-PHASE RESPONSE FOLLOWING MAJOR LIVER RESECTION

S. Meijer, H. Prins, C. Meijer, 2004, Shock.

Surgery in Malawi – the training of clinical officers

P. V. van Leeuwen, P. Jiskoot, J. J. C. van Amelsfoort, 2010, Tropical doctor.

Arginase release from red blood cells: possible link in transfusion induced immune suppression?

P. Huygens, H. Prins, L. Thijs, 2001, Shock.

T cell infiltration on local CpG-B delivery in early-stage melanoma is predominantly related to CLEC9A+CD141+ cDC1 and CD14+ antigen-presenting cell recruitment

T. D. de Gruijl, P. V. van Leeuwen, R. Scheper, 2021, Journal for ImmunoTherapy of Cancer.

Sampling tumor-draining lymph nodes for phenotypic and functional analysis of dendritic cells and T cells.

D. Busch, S. Meijer, T. D. de Gruijl, 2002, The American journal of pathology.

Metastatic pattern of CC531 colon carcinoma cells in the abdominal cavity: an experimental model of peritoneal carcinomatosis in rats.

R. Bleichrodt, S. Meijer, P. V. van Leeuwen, 2001, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

The bioelectrical impedance phase angle as an indicator of undernutrition and adverse clinical outcome in cardiac surgical patients.

B. D. de Mol, P. V. van Leeuwen, R. de Vos, 2012, Clinical nutrition.

4-1BB-mediated expansion affords superior detection of in vivo primed effector memory CD8+ T cells from melanoma sentinel lymph nodes.

C. June, S. Meijer, T. D. de Gruijl, 2010, Clinical immunology.

Prognosis in patients with sentinel node-positive melanoma is accurately defined by the combined Rotterdam tumor load and Dewar topography criteria.

I. V. D. van der Ploeg, A. Eggermont, A. Testori, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Absence of Granzyme B Positive Tumour-Infiltrating Lymphocytes in Primary Melanoma Excisional Biopsies is Strongly Associated with the Presence of Sentinel Lymph Node Metastasis

C. Meijer, T. D. de Gruijl, P. V. van Leeuwen, 2009, Cellular oncology : the official journal of the International Society for Cellular Oncology.

The prominent role of the liver in the elimination of asymmetric dimethylarginine (ADMA) and the consequences of impaired hepatic function.

M. Siroen, P. V. van Leeuwen, T. Teerlink, 2008, JPEN. Journal of parenteral and enteral nutrition.

Sentinel lymph node investigation in melanoma: detailed analysis of the yield from step sectioning and immunohistochemistry

P. V. van Diest, H. Gietema, S. Meijer, 2004, Journal of Clinical Pathology.

Assessment of Lesion Response in the Initial Radioiodine Treatment of Differentiated Thyroid Cancer Using 124I PET Imaging

T. Poeppel, A. Bockisch, W. Jentzen, 2014, The Journal of Nuclear Medicine.

Immune‐stimulating effects of low‐dose perioperative recombinant granulocyte–macrophage colony‐stimulating factor in patients operated on for primary colorectal carcinoma

M. Cuesta, S. Meijer, P. V. van Leeuwen, 2001, The British journal of surgery.

A prospective randomized study of the systemic immune response after laparoscopic and conventional Nissen fundoplication.

M. Cuesta, S. Meijer, P. V. van Leeuwen, 1999, Surgery.

The clinical significance of asymmetric dimethylarginine.

H. Prins, R. Nijveldt, M. Siroen, 2006, Annual review of nutrition.

Cardiac surgery-specific screening tool identifies preoperative undernutrition in cardiac surgery.

B. D. de Mol, P. V. van Leeuwen, R. de Vos, 2013, The Annals of thoracic surgery.

Preoperative and postoperative agreement in fat free mass (FFM) between bioelectrical impedance spectroscopy (BIS) and dual-energy X-ray absorptiometry (DXA) in patients undergoing cardiac surgery.

B. D. de Mol, P. V. van Leeuwen, H. Verberne, 2010, Clinical nutrition.

Accurate perioperative flow measurement of the portal vein and hepatic and renal artery: a role for preoperative MRI?

C. Dejong, G. Ligthart-Melis, P. G. Boelens, 2012, European journal of radiology.

Hypothermic renal perfusion during aortic surgery reduces the presence of lipocalin-2 and preserves renal extraction of dimethylarginines in rats.

K. Yeung, P. V. van Leeuwen, G. Tangelder, 2011, American journal of physiology. Renal physiology.

Open surgical repair of ruptured juxtarenal aortic aneurysms with and without renal cooling: observations regarding morbidity and mortality.

E. D. L. de Lange-de Klerk, H. Coveliers, K. Yeung, 2010, Journal of vascular surgery.

Local Adjuvant Treatment with Low-Dose CpG-B Offers Durable Protection against Disease Recurrence in Clinical Stage I–II Melanoma: Data from Two Randomized Phase II Trials

T. D. de Gruijl, P. V. van Leeuwen, R. Scheper, 2017, Clinical Cancer Research.

Arming the Melanoma Sentinel Lymph Node through Local Administration of CpG-B and GM-CSF: Recruitment and Activation of BDCA3/CD141+ Dendritic Cells and Enhanced Cross-Presentation

T. D. de Gruijl, P. V. van Leeuwen, R. Scheper, 2015, Cancer Immunology Research.

The sentinel lymph node status is an important factor for predicting clinical outcome in patients with Stage I or II cutaneous melanoma

P. V. van Diest, E. D. L. de Lange-de Klerk, S. Meijer, 2001, Cancer.

Sarcopenic obesity is associated with adverse clinical outcome after cardiac surgery.

B. D. de Mol, P. V. van Leeuwen, R. de Vos, 2013, Nutrition, metabolism, and cardiovascular diseases : NMCD.

Transjugular intrahepatic portosystemic shunt-placement increases arginine/asymmetric dimethylarginine ratio in cirrhotic patients.

M. Siroen, P. V. van Leeuwen, T. Teerlink, 2008, World journal of gastroenterology.

Determination of arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in human plasma and other biological samples by high-performance liquid chromatography.

R. Nijveldt, P. V. van Leeuwen, T. Teerlink, 2002, Analytical biochemistry.

Bactericidal/Permeability-Increasing Protein Preserves Leukocyte Functions After Major Liver Resection

M. Cuesta, H. Prins, C. Meijer, 2000, Annals of surgery.

Aortic Aneurysm Repair Is Associated with a Lower Inflammatory Response Compared with Surgery for Inflammatory Bowel Disease

M. Cuesta, L. Moldawer, S. Meijer, 2004, European Surgical Research.

Gastric emptying, glucose metabolism and gut hormones: evaluation of a common preoperative carbohydrate beverage.

J. Holst, B. Uitdehaag, A. Heijboer, 2011, Nutrition.

Postoperative loss of skeletal muscle mass, complications and quality of life in patients undergoing cardiac surgery.

B. D. de Mol, P. V. van Leeuwen, H. Verberne, 2012, Nutrition.

Preservation of the gut by preoperative carbohydrate loading improves postoperative food intake.

H. Rijna, P. V. van Leeuwen, A. Oosting, 2013, Clinical nutrition.

Effects of a Carbohydrate‐, Glutamine‐, and Antioxidant‐Enriched Oral Nutrition Supplement on Major Surgery‐Induced Insulin Resistance: A Randomized Pilot Study

J. Twisk, M. Soeters, P. V. van Leeuwen, 2017, JPEN. Journal of parenteral and enteral nutrition.

Role of dimethylarginine dimethylaminohydrolase activity in regulation of tissue and plasma concentrations of asymmetric dimethylarginine in an animal model of prolonged critical illness.

G. Van den Berghe, M. Davids, B. Ellger, 2012, Metabolism: clinical and experimental.

Preoperative protein and energy intake and postoperative complications in well-nourished, non-hospitalized elderly cardiac surgery patients.

B. D. de Mol, P. V. van Leeuwen, R. de Vos, 2009, Clinical nutrition.

Glycemic control modulates arginine and asymmetrical-dimethylarginine levels during critical illness by preserving dimethylarginine-dimethylaminohydrolase activity.

G. Van den Berghe, B. Ellger, P. V. van Leeuwen, 2008, Endocrinology.

A Carbohydrate-Rich Beverage Prior to Surgery Prevents Surgery-Induced Immunodepression: A Randomized, Controlled, Clinical Trial.

B. Uitdehaag, P. V. van Leeuwen, R. J. V. van Schijndel, 2006, JPEN. Journal of parenteral and enteral nutrition.

Effects of preoperative flavonoid supplementation on different organ functions in rats.

P. G. Boelens, R. Nijveldt, P. V. van Leeuwen, 2006, JPEN. Journal of parenteral and enteral nutrition.

A fast and accurate method to measure both oxidative stress and vitality in a single organ slice.

P. V. van Leeuwen, K. van Norren, E. C. van Hoorn, 2003, Analytical biochemistry.

Effect of perioperative nutrition, with and without arginine supplementation, on nutritional status, immune function, postoperative morbidity, and survival in severely malnourished head and neck cancer patients.

G. Snow, D. Kuik, P. V. van Leeuwen, 2001, The American journal of clinical nutrition.

Perioperative arginine-supplemented nutrition in malnourished patients with head and neck cancer improves long-term survival.

D. Kuik, C. Leemans, P. V. van Leeuwen, 2010, The American journal of clinical nutrition.

Human taurine metabolism: fluxes and fractional extraction rates of the gut, liver, and kidneys.

G. Ligthart-Melis, M. Siroen, P. V. van Leeuwen, 2012, Metabolism: clinical and experimental.

Preoperative supplementation with a carbohydrate mixture decreases organ dysfunction-associated risk factors.

P. V. van Leeuwen, K. van Norren, K. Lamb, 2005, Clinical nutrition.

Plasma ADMA concentrations at birth and mechanical ventilation in preterm infants: A prospective pilot study

J. Twisk, J. Twisk, P. V. van Leeuwen, 2008, Pediatric pulmonology.

Glutamine alimentation in catabolic state.

S. Meijer, P. G. Boelens, R. Nijveldt, 2001, The Journal of nutrition.

Accurate prediction of xanthine oxidase inhibition based on the structure of flavonoids.

R. Nijveldt, P. V. van Leeuwen, K. van Norren, 2002, European journal of pharmacology.

Glutamine is an important precursor for de novo synthesis of arginine in humans.

C. Dejong, N. Deutz, G. Ligthart-Melis, 2008, The American journal of clinical nutrition.

Net renal extraction of asymmetrical (ADMA) and symmetrical (SDMA) dimethylarginine in fasting humans.

C. Stehouwer, R. Nijveldt, P. V. van Leeuwen, 2002, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Glutamine-enriched enteral diet increases renal arginine production.

M. Boermeester, P. V. van Leeuwen, H. Sauerwein, 1994, JPEN. Journal of parenteral and enteral nutrition.

Gut endotoxin restriction prevents catabolic changes in glutamine metabolism after surgery in the bile duct-ligated rat.

P. V. van Leeuwen, F. Bloemers, T. Teerlink, 1997, Annals of surgery.

Rapid determination of glutamine in biological samples by high-performance liquid chromatography.

P. V. van Leeuwen, T. Teerlink, A. Houdijk, 1993, Clinica chimica acta; international journal of clinical chemistry.

The route of administration (enteral or parenteral) affects the conversion of isotopically labeled L-[2-15N]glutamine into citrulline and arginine in humans.

C. Dejong, N. Deutz, G. Ligthart-Melis, 2007, JPEN. Journal of parenteral and enteral nutrition.

Intestinal and hepatic metabolism of glutamine and citrulline in humans

C. Dejong, N. Deutz, G. Ligthart-Melis, 2007, The Journal of physiology.

Porcine intestinal ammonia liberation. Influence of food intake, lactulose and neomycin treatment.

P. V. van Leeuwen, P. Soeters, C. V. Van Berlo, 1988, Journal of hepatology.

The prognostic value of severe malnutrition in the development of nonthyroidal illness in head and neck cancer patients.

C. Leemans, P. V. van Leeuwen, H. Sauerwein, 2006, JPEN. Journal of parenteral and enteral nutrition.

Glutamine-enriched enteral nutrition in multiple trauma patients.

P. V. van Leeuwen, A. Houdijk, P. V. Leeuwen, 2000, Nutrition.

Glutamine-enriched enteral feeding in trauma patients: reduced infectious morbidity is not related to changes in endocrine and metabolic responses.

R. Nijveldt, P. V. van Leeuwen, A. Houdijk, 1999, JPEN. Journal of parenteral and enteral nutrition.

Rationale and design of a proof-of-concept trial investigating the effect of uninterrupted perioperative (par)enteral nutrition on amino acid profile, cardiomyocytes structure, and cardiac perfusion and metabolism of patients undergoing coronary artery bypass grafting

M. Davids, B. D. de Mol, W. Kok, 2011, Journal of cardiothoracic surgery.

Local delivery of CpG-B and GM-CSF induces concerted activation of effector and regulatory T cells in the human melanoma sentinel lymph node

T. D. de Gruijl, P. V. van Leeuwen, S. Santegoets, 2016, Cancer Immunology, Immunotherapy.

Intestinal renal metabolism of L-citrulline and L-arginine following enteral or parenteral infusion of L-alanyl-L-[2,15N]glutamine or L-[2,15N]glutamine in mice.

C. Dejong, N. Deutz, P. G. Boelens, 2005, American journal of physiology. Gastrointestinal and liver physiology.

Jejunal feeding is followed by a greater rise in plasma cholecystokinin, peptide YY, glucagon-like peptide 1, and glucagon-like peptide 2 concentrations compared with gastric feeding in vivo in humans: a randomized trial.

J. Holst, A. Heijboer, L. V. van Loon, 2016, The American journal of clinical nutrition.

The impact of low preoperative fat-free body mass on infections and length of stay after cardiac surgery: a prospective cohort study.

B. D. de Mol, P. V. van Leeuwen, R. de Vos, 2011, The Journal of thoracic and cardiovascular surgery.

Preoperative feeding preserves heart function and decreases oxidative injury in rats.

H. Prins, P. G. Boelens, R. Nijveldt, 2005, Nutrition.

The feeding route (enteral or parenteral) affects the plasma response of the dipetide Ala-Gln and the amino acids glutamine, citrulline and arginine, with the administration of Ala-Gln in preoperative patients

P. G. Boelens, P. V. van Leeuwen, L. Cynober, 2005, British Journal of Nutrition.

IL-1ra administration does not improve cardiac function in patients with severe sepsis.

J. Bander, S. Nasraway, J. Vincent, 1999, Journal of critical care.

Infrarenal aortic‐clamping after renal ischaemia aggravates acute renal failure

K. Yeung, P. V. van Leeuwen, G. Tangelder, 2011, European journal of clinical investigation.

Matched skin and sentinel lymph node samples of melanoma patients reveal exclusive migration of mature dendritic cells.

S. Meijer, T. D. de Gruijl, P. V. van Leeuwen, 2005, The American journal of pathology.

The effect of mild endotoxemia during low arginine plasma levels on organ blood flow in rats

H. Prins, L. Thijs, P. V. van Leeuwen, 1999, Critical care medicine.

Hepatic failure and coma after liver resection is reversed by manipulation of gut contents: the role of endotoxin.

D. Wilmore, P. V. van Leeuwen, M. Rodrick, 1991, Surgery.

The human liver clears both asymmetric and symmetric dimethylarginine

R. Nijveldt, M. Siroen, P. V. van Leeuwen, 2005, Hepatology.

Handling of asymmetrical dimethylarginine and symmetrical dimethylarginine by the rat kidney under basal conditions and during endotoxaemia.

H. Prins, C. Stehouwer, R. Nijveldt, 2003, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

The liver is an important organ in the metabolism of asymmetrical dimethylarginine (ADMA).

R. Nijveldt, M. Siroen, P. V. van Leeuwen, 2003, Clinical nutrition.

The impact of nutritional status on the prognoses of patients with advanced head and neck cancer

G. Snow, D. Kuik, P. V. van Leeuwen, 1999, Cancer.

Assessment of malnutrition parameters in head and neck cancer and their relation to postoperative complications

G. Snow, D. Kuik, P. V. van Leeuwen, 1997, Head & neck.

Melanoma Sequentially Suppresses Different DC Subsets in the Sentinel Lymph Node, Affecting Disease Spread and Recurrence

T. D. de Gruijl, P. V. van Leeuwen, R. Scheper, 2017, Cancer Immunology Research.

Effects of major liver resection, with or without recombinant bactericidal/permeability‐increasing protein (rBPI21), on the angiogenic profile of patients with metastatic colorectal carcinoma

M. Cuesta, S. Meijer, C. Meijer, 2003, Journal of surgical oncology.

Liver failure induces a systemic inflammatory response. Prevention by recombinant N-terminal bactericidal/permeability-increasing protein.

M. Boermeester, M. Cuesta, C. Hack, 1995, The American journal of pathology.

Survival of malnourished head and neck cancer patients can be predicted by human leukocyte antigen-DR expression and interleukin-6/tumor necrosis factor-alpha response of the monocyte.

G. Snow, D. Kuik, M. Siroen, 2000, JPEN. Journal of parenteral and enteral nutrition.

No Compensatory Upregulation of Placental Dimethylarginine Dimethylaminohydrolase Activity in Preeclampsia

R. Nijveldt, M. Siroen, P. V. van Leeuwen, 2006, Gynecologic and Obstetric Investigation.

Plasma amino acids determined by liquid chromatography within 17 minutes.

P. V. van Leeuwen, A. Houdijk, T. Terrlink, 1994, Clinical chemistry.

Primary immune response to keyhole limpet haemocyanin following trauma in relation to low plasma glutamine

S. Meijer, P. G. Boelens, P. V. van Leeuwen, 2004, Clinical and experimental immunology.

Human Nutrition and Metabolism Glutamine-Enriched Enteral Nutrition Increases HLA-DR Expression on Monocytes of Trauma Patients

J. Puyana, L. Thijs, P. G. Boelens, 2002 .

Perioperative Anti-endotoxin Strategies.

C. Meijer, P. V. van Leeuwen, M. A. Cuesta, 1997, Scandinavian journal of gastroenterology.

Low arginine/asymmetric dimethylarginine ratio deteriorates systemic hemodynamics and organ blood flow in a rat model

E. Bloemena, H. Prins, P. V. van Leeuwen, 2009, Critical care medicine.

Elevation of asymmetric dimethylarginine (ADMA) in patients developing hepatic failure after major hepatectomy.

M. Cuesta, S. Meijer, H. Prins, 2004, JPEN. Journal of parenteral and enteral nutrition.

Glutamine: recent developments in research on the clinical significance of glutamine

P. G. Boelens, P. V. van Leeuwen, G. C. Melis, 2004, Current opinion in clinical nutrition and metabolic care.

Route of administration (enteral or parenteral) affects the contribution of L-glutamine to de novo L-arginine synthesis in mice: a stable-isotope study.

N. Deutz, P. G. Boelens, P. V. van Leeuwen, 2006, American journal of physiology. Endocrinology and metabolism.

Major liver resection results in a changed plasma amino acid pattern as reflected by a decreased Fischer ratio which improves by bactericidal/permeability increasing protein.

M. Cuesta, I. B. Borel Rinkes, C. V. D. van de Velde, 2001, Liver.

Is major liver surgery associated with an increased systemic inflammatory response? A prospective comparison of hemihepatectomy and other major abdominal surgery.

M. Cuesta, C. Hack, S. Meijer, 1999, Liver.

Clinical relevance of parasternal uptake in sentinel node procedure for breast cancer

S. Meijer, P. V. van Leeuwen, R. Pijpers, 2004, Journal of surgical oncology.

Plasma taurine concentrations increase after enteral glutamine supplementation in trauma patients and stressed rats.

P. G. Boelens, P. V. van Leeuwen, T. Teerlink, 2003, The American journal of clinical nutrition.

Cold Renal Perfusion During Simulation of Juxtarenal Aortic Aneurysm Repair Reduces Systemic Oxidative Stress and Sigmoid Damage in Rats.

K. Yeung, P. V. van Leeuwen, W. Wisselink, 2019, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

Endotoxin and interleukin‐1 related hepatic inflammatory response promotes liver failure after partial hepatectomy

M. Boermeester, W. Frederiks, P. V. van Leeuwen, 1995, Hepatology.

Elimination of asymmetric dimethylarginine by the kidney and the liver: a link to the development of multiple organ failure?

R. Nijveldt, M. Siroen, P. V. van Leeuwen, 2004, The Journal of nutrition.

The asymmetrical dimethylarginine (ADMA)-multiple organ failure hypothesis.

R. Nijveldt, P. V. van Leeuwen, T. Teerlink, 2003, Clinical nutrition.

Gut and liver handling of asymmetric and symmetric dimethylarginine in the rat under basal conditions and during endotoxemia

R. Nijveldt, M. Siroen, P. V. van Leeuwen, 2004, Liver international : official journal of the International Association for the Study of the Liver.

Dietary glutamine supplementation reduces plasma nitrate levels in rats.

P. V. van Leeuwen, T. Teerlink, A. Houdijk, 1998, Clinical nutrition.

Comparison of two devices for the treatment of keloid scars with the use of intralesional cryotherapy: An experimental study.

A. J. van der Veen, P. V. van Leeuwen, Anne-Eva J Bulstra, 2015, Cryobiology.

ENDOTOXIN‐ AND CYTOKINE‐MEDIATED EFFECTS ON LIVER CELL PROLIFERATION AND LIPID METABOLISM AFTER PARTIAL HEPATECTOMY: A STUDY WITH RECOMBINANT N‐TERMINAL BACTERICIDAL/PERMEABILITY‐INCREASING PROTEIN AND INTERLEUKIN‐1 RECEPTOR ANTAGONIST

M. Boermeester, W. Frederiks, P. V. van Leeuwen, 1996, The Journal of pathology.

Enteral administration of alanyl-[2-(15)N]glutamine contributes more to the de novo synthesis of arginine than does intravenous infusion of the dipeptide in humans.

N. Deutz, G. Ligthart-Melis, P. G. Boelens, 2009, The American journal of clinical nutrition.

Low plasma concentrations of arginine and asymmetric dimethylarginine in premature infants with necrotizing enterocolitis.

W. Fetter, R. Nijveldt, M. Siroen, 2007, The British journal of nutrition.

Local Administration of Granulocyte/Macrophage Colony-stimulating Factor Increases the Number and Activation State of Dendritic Cells in the Sentinel Lymph Node of Early-Stage Melanoma

P. V. van Diest, H. Gietema, S. Meijer, 2004, Cancer Research.

Perioperative enteral nutrition and quality of life of severely malnourished head and neck cancer patients: a randomized clinical trial.

D. Kuik, P. V. van Leeuwen, H. Vondeling, 2000, Clinical nutrition.

The influence of laparoscopic surgery on postoperative polymorphonuclear leukocyte function

M. Cuesta, S. Meijer, P. V. van Leeuwen, 2000, Surgical Endoscopy.

Laparoscopic surgery preserves monocyte-mediated tumor cell killing in contrast to the conventional approach

M. Cuesta, P. V. van Leeuwen, C. Sietses, 2000, Surgical Endoscopy.

Interleukin-10 appearance following thoraco-abdominal and abdominal aortic aneurysm repair is associated with the duration of visceral ischaemia.

L. Moldawer, J. Rauwerda, H. Oldenburg, 2000, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

Risk factors for multiple organ system failure and death in critically injured patients.

M. Cuesta, P. V. van Leeuwen, P. V. Leeuwen, 1993, Surgery.

The effect of fibers on coagulation of casein-based enteral nutrition in an artificial gastric digestion model.

H. Rijna, P. V. van Leeuwen, M. Minor, 2014, Food & function.

Surgical Excision with Adjuvant Irradiation for Treatment of Keloid Scars: A Systematic Review

M. Heymans, J. Ket, P. V. van Leeuwen, 2015, Plastic and reconstructive surgery. Global open.

Systemic and Peritoneal Inflammatory Response After Laparoscopic or Conventional Colon Resection in Cancer Patients

M. Cuesta, P. V. van Leeuwen, C. Sietses, 2003, Diseases of the colon and rectum.

Intralesional Cryotherapy for the Treatment of Keloid Scars: Evaluating Effectiveness

J. Ket, P. V. van Leeuwen, M. Ritt, 2015, Plastic and reconstructive surgery. Global open.

Intralesional Cryotherapy for Treatment of Keloid Scars: A Prospective Study

P. V. van Zuijlen, M. V. D. van der Wal, P. V. van Leeuwen, 2015, Plastic and reconstructive surgery.

A new argon gas-based device for the treatment of keloid scars with the use of intralesional cryotherapy.

P. V. van Leeuwen, Anne-Eva J Bulstra, F. Niessen, 2014, Journal of plastic, reconstructive & aesthetic surgery : JPRAS.

Non-Radical Diagnostic Biopsies Do Not Negatively Influence Melanoma Patient Survival

S. Meijer, P. V. van Leeuwen, B. Sluijter, 2006, Annals of Surgical Oncology.

Differences in immune status between well-nourished and malnourished head and neck cancer patients.

G. Snow, P. V. van Leeuwen, R. Riezebos, 1998, Clinical nutrition.

Impaired leukocyte phagocytosis in patients undergoing hemihepatectomy for liver metastases.

C. Hack, S. Meijer, H. Prins, 1999, Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

High-Dose-Rate Brachytherapy for the Treatment of Recalcitrant Keloids: A Unique, Effective Treatment Protocol

P. V. van Leeuwen, Anne-Eva J Bulstra, F. Niessen, 2014, Plastic and reconstructive surgery.

Reply: High-dose-rate brachytherapy for the treatment of recalcitrant keloids: a unique effective treatment protocol.

P. V. van Leeuwen, Anne-Eva J Bulstra, F. Niessen, 2015, Plastic and reconstructive surgery.

Clinical significance of translocation.

M. Boermeester, M. Cuesta, P. V. van Leeuwen, 1994, Gut.

Oral nutritional supplements containing (n-3) polyunsaturated fatty acids affect the nutritional status of patients with stage III non-small cell lung cancer during multimodality treatment.

E. Smit, M. Paul, A. Heijboer, 2010, The Journal of nutrition.

n-3 PUFAs in cancer, surgery, and critical care: a systematic review on clinical effects, incorporation, and washout of oral or enteral compared with parenteral supplementation.

P. V. van Leeuwen, M. A. E. van Bokhorst-de van der Schueren, J. Langius, 2011, The American journal of clinical nutrition.

Clinical outcome of stage I/II melanoma patients after selective sentinel lymph node dissection: long-term follow-up results.

H. Gietema, S. Meijer, P. V. van Leeuwen, 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Selective bowel decontamination and liver regeneration.

M. Boermeester, P. V. van Leeuwen, R. Wesdorp, 1992, Gastroenterology.

Perioperative IFN-alpha to avoid surgically induced immune suppression in colorectal cancer patients.

S. Meijer, P. V. van Leeuwen, P. V. Leeuwen, 2006, Histology and histopathology.

The sentinel node procedure in cutaneous melanoma: an overview of 6 years’ experience

S. Meijer, P. V. van Leeuwen, P. V. Leeuwen, 1999, European Journal of Nuclear Medicine.

GUT ENDOTOXIN RESTRICTION IMPROVES POSTOPERATIVE HEMODYNAMICS IN THE BILE DUCT -LIGATED RAT

L. Thijs, P. V. van Leeuwen, A. Houdijk, 1998, Shock.

Oral nutritional supplements containing n-3 polyunsaturated fatty acids affect quality of life and functional status in lung cancer patients during multimodality treatment: an RCT

E. Smit, M. Paul, M. Spreeuwenberg, 2012, European Journal of Clinical Nutrition.

Intradermal CpG-B Activates Both Plasmacytoid and Myeloid Dendritic Cells in the Sentinel Lymph Node of Melanoma Patients

S. Meijer, T. D. de Gruijl, P. V. van Leeuwen, 2007, Clinical Cancer Research.

Glutamine-enriched enteral nutrition increases in vitro interferon-gamma production but does not influence the in vivo specific antibody response to KLH after severe trauma. A prospective, double blind, randomized clinical study.

J. Puyana, P. G. Boelens, P. V. van Leeuwen, 2004, Clinical nutrition.

Effect of Oral Taurine on Morbidity and Mortality in Elderly Hip Fracture Patients: A Randomized Trial

Arnoud A. Bruins, J. Twisk, P. V. van Leeuwen, 2015, International journal of molecular sciences.

Operative treatment of Smith-Goyrand fractures.

P. V. van Leeuwen, P. Broos, P. Rommens, 1990, Injury.

Glutamine-enriched enteral diet increases splanchnic blood flow in the rat.

M. Boermeester, P. V. van Leeuwen, H. Sauerwein, 1994, The American journal of physiology.

Preoperative nutrition status and postoperative outcome in elderly general surgery patients: a systematic review.

P. V. van Leeuwen, A. Houdijk, T. van der Ploeg, 2013, JPEN. Journal of parenteral and enteral nutrition.

Adaptations of Arginine's Intestinal-Renal Axis in Cachectic Tumor-Bearing Rats

J. Bading, P. V. van Leeuwen, A. Houdijk, 2015, Nutrition and cancer.

Immunomodulation of the melanoma sentinel lymph node: a novel adjuvant therapeutic option.

S. Meijer, T. D. de Gruijl, P. V. van Leeuwen, 2006, Immunobiology.

Preoperative fasting: an outdated concept?

P. G. Boelens, R. Nijveldt, J. Diks, 2005, JPEN. Journal of parenteral and enteral nutrition.

Use of a mixture of medium-chain triglycerides and longchain triglycerides versus long-chain triglycerides in critically ill surgical patients: a randomized prospective double-blind study.

H. Prins, P. V. van Leeuwen, R. Wesdorp, 1998, Clinical nutrition.

Gut Injury after Major Abdominal Surgery: The Role of Neutrophil Activation and Enteral Nutrition

R. Bleichrodt, S. Meijer, H. Prins, 1998, Transfusion Medicine and Hemotherapy.

Specific amino acids in the critically ill patient—Exogenous glutamine/arginine: A common denominator?

C. Dejong, G. Ligthart-Melis, P. G. Boelens, 2007, Critical care medicine.

Reply: Intralesional Cryotherapy for the Treatment of Keloid Scars: A Prospective Study.

P. V. van Zuijlen, M. V. D. van der Wal, P. V. van Leeuwen, 2015, Plastic and reconstructive surgery.

Perioperative glutamine supplementation restores disturbed renal arginine synthesis after open aortic surgery: a randomized controlled clinical trial.

P. V. van Leeuwen, H. Schierbeek, A. Beishuizen, 2016, American journal of physiology. Renal physiology.

Intravenous glutamine supplementation enhances renal de novo arginine synthesis in humans: a stable isotope study.

P. V. van Leeuwen, J. Luttikhold, J. V. van Goudoever, 2014, The American journal of clinical nutrition.

Nutrition before, during, and after surgery increases the arginine:asymmetric dimethylarginine ratio and relates to improved myocardial glucose metabolism: a randomized controlled trial.

M. Davids, B. D. de Mol, W. Kok, 2014, The American journal of clinical nutrition.

The flux of arginine after ischemia-reperfusion in the rat kidney.

H. Prins, R. Nijveldt, P. V. van Leeuwen, 2002, Kidney international.

Low arginine plasma levels do not aggravate renal blood flow after experimental renal ischaemia/reperfusion.

H. Prins, P. G. Boelens, R. Nijveldt, 2001, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

Nutrition Before, During, and after Surgery Increases the Arginine/adma Ratio and Relates to Improved Myocardial Glucose Metabolism: a Randomized Controlled Trial

M. Davids, B. D. de Mol, W. Kok, 2022 .

A carbohydrate-rich beverage prior to surgery prevents surgery-induced immunodepression: a randomized, controlled, clinical trial.

B. Uitdehaag, R. S. V. STRACK VAN SCHIJNDEL, P. V. van Leeuwen, 2006, JPEN. Journal of parenteral and enteral nutrition.

Antioxidant-enriched enteral nutrition and immuno-inflammatory response after major gastrointestinal tract surgery

J. Twisk, G. Ligthart-Melis, P. G. Boelens, 2009, British Journal of Nutrition.

Carbohydrate supplementation before operation retains intestinal barrier function and lowers bacterial translocation in a rat model of major abdominal surgery.

P. V. van Leeuwen, A. Oosting, K. van Norren, 2008, JPEN. Journal of parenteral and enteral nutrition.

Antioxidant enriched enteral nutrition and oxidative stress after major gastrointestinal tract surgery.

J. Twisk, P. Scheffer, G. Ligthart-Melis, 2008, World journal of gastroenterology.

Interleukin-1 blockade attenuates mediator release and dysregulation of the hemostatic mechanism during human sepsis.

M. Boermeester, S. Lowry, C. Hack, 1995, Archives of surgery.

Imbalance of arginine and asymmetric dimethylarginine is associated with markers of circulatory failure, organ failure and mortality in shock patients

B. D. de Mol, P. V. van Leeuwen, H. O. Oudemans-van Straaten, 2011, British Journal of Nutrition.

Imbalance of Arginine and Adma Is Associated with Markers of Circulatory Failure, Organ Failure and Mortality in Shock Patients

B. D. de Mol, P. V. van Leeuwen, H. O. Oudemans-van Straaten, 2022 .

A rare acute pulmonary lesion after blunt chest trauma: a case report.

P. V. van Leeuwen, R. Versteylen, 1990, European journal of radiology.

Kupffer cell depletion by CI2MDP-liposomes alters hepatic cytokine expression and delays liver regeneration after partial hepatectomy.

H. Schouten, S. Meijer, N. Van Rooijen, 2000, Liver.

A new key player in VEGF-dependent angiogenesis in human hepatocellular carcinoma: dimethylarginine dimethylaminohydrolase 1

D. Stolz, D. Geller, P. V. van Leeuwen, 2017, Angiogenesis.

Arginine deficiency in bile duct-ligated rats after surgery: the role of plasma arginase and gut endotoxin restriction.

P. V. van Leeuwen, T. Teerlink, A. Houdijk, 1997, Gastroenterology.

Pre-cachexia and cachexia at diagnosis of stage III non-small-cell lung carcinoma: an exploratory study comparing two consensus-based frameworks

E. Smit, M. Muscaritoli, P. V. van Leeuwen, 2012, British Journal of Nutrition.

Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation.

S. Meijer, T. D. de Gruijl, P. V. van Leeuwen, 2011, Blood.

Preoperative granulocyte/macrophage colony-stimulating factor (GM-CSF) increases hepatic dendritic cell numbers and clustering with lymphocytes in colorectal cancer patients.

G. Meijer, S. Meijer, T. Geijtenbeek, 2006, Immunobiology.

Sentinel Lymph Node Tumor Load: An Independent Predictor of Additional Lymph Node Involvement and Survival in Melanoma

H. Gietema, P. Diest, S. Meijer, 2005, Annals of Surgical Oncology.

Local Administration of PF-3512676 CpG-B Instigates Tumor-Specific CD8+ T-Cell Reactivity in Melanoma Patients

S. Meijer, J. Haanen, T. D. de Gruijl, 2008, Clinical Cancer Research.

Tumor-Specific CD8+ T Cell Reactivity in the Sentinel Lymph Node of GM-CSF–Treated Stage I Melanoma Patients is Associated with High Myeloid Dendritic Cell Content

S. Meijer, J. Haanen, T. D. de Gruijl, 2006, Clinical Cancer Research.

Unpredictability of lymphatic drainage patterns in melanoma patients

S. Meijer, P. V. van Leeuwen, R. Pijpers, 2002, European Journal of Nuclear Medicine and Molecular Imaging.

Coagulopathy following major liver resection: the effect of rBPI21 and the role of decreased synthesis of regulating proteins by the liver.

M. Cuesta, I. B. Borel Rinkes, C. V. D. van de Velde, 2001, Shock.

Novel nutritional substrates in surgery

P. V. van Leeuwen, J. Luttikhold, A. Houdijk, 2013, Proceedings of the Nutrition Society.

Influence of L-glutamine on the cytotoxicity of human monocytes against the SW948, a colon carcinoma cell line.

S. Meijer, P. V. van Leeuwen, R. Beelen, 1997, Clinical nutrition.

Morphological effects of high dose neomycin sulphate on the small and large intestine.

J. Drukker, P. V. van Leeuwen, P. Soeters, 1986, Acta morphologica Neerlando-Scandinavica.

The Influence of Pregnancy on the Recurrence of Cutaneous Malignant Melanoma in Women

P. V. van Leeuwen, M. Albersen, V. I. Westerling, 2010, Dermatology research and practice.

Glutamate reduces experimental intestinal hyperpermeability and facilitates glutamine support of gut integrity.

P. V. van Leeuwen, A. Houdijk, M. Vermeulen, 2011, World journal of gastroenterology.

The effects of surgery, with or without rhGM-CSF, on the angiogenic profile of patients treated for colorectal carcinoma.

M. Cuesta, S. Meijer, P. V. van Leeuwen, 2004, Cytokine.

The citrulline generation test: proposal for a new enterocyte function test

A. V. van Bodegraven, P. V. van Leeuwen, T. Teerlink, 2008, Alimentary pharmacology & therapeutics.

Enteral Glutamine Administration in Critically Ill Nonseptic Patients Does Not Trigger Arginine Synthesis

P. V. van Leeuwen, J. V. van Goudoever, A. Houdijk, 2016, Journal of nutrition and metabolism.

Interorgan amino acid exchange in humans: consequences for arginine and citrulline metabolism.

C. Dejong, N. Deutz, P. G. Boelens, 2007, The American journal of clinical nutrition.

Glutamine: precursor or nitrogen donor for citrulline synthesis?

N. Deutz, G. Ligthart-Melis, P. V. van Leeuwen, 2010, American journal of physiology. Endocrinology and metabolism.

Accuracy of quick and easy undernutrition screening tools--Short Nutritional Assessment Questionnaire, Malnutrition Universal Screening Tool, and modified Malnutrition Universal Screening Tool--in patients undergoing cardiac surgery.

B. D. de Mol, P. V. van Leeuwen, R. de Vos, 2011, Journal of the American Dietetic Association.

Role of the human erythrocyte in generation and storage of asymmetric dimethylarginine.

M. Davids, R. Nijveldt, P. V. van Leeuwen, 2012, American journal of physiology. Heart and circulatory physiology.

Nutrition During Trimodality Treatment in Stage III Non-small Cell Lung Cancer: Not Only Important for Underweight Patients

E. Smit, M. Paul, J. Oosterhuis, 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Hypertaurinemia in bile duct-ligated rats after surgery: the effect of gut endotoxin restriction on organ fluxes and oxidative status.

M. Siroen, P. V. van Leeuwen, T. Teerlink, 2006, JPEN. Journal of parenteral and enteral nutrition.

High plasma levels of arginine and liver arginase in Kupffer-cell-depleted rats after partial hepatectomy.

H. Prins, C. Meijer, R. Nijveldt, 2000, Journal of hepatology.

The Mechanisms and Effects of Physical Activity on Breast Cancer

P. V. van Leeuwen, E. Wörner, D. Verlaan, 2017, Clinical breast cancer.

Systemic and Peritoneal Inflammatory Response After Laparoscopic or Conventional Colon Resection in Cancer Patients: A Prospective, Randomized Trial

M. Cuesta, P. V. van Leeuwen, C. Sietses, 2003 .

Modulation of asymmetric dimethylarginine in critically ill patients receiving intensive insulin treatment: A possible explanation of reduced morbidity and mortality?*

G. Van den Berghe, R. Nijveldt, M. Siroen, 2005, Critical care medicine.

rBPI2, IN THE PREVENTION OF THE INFLAMMATORY RESPONSE AFTER LIVER RESECTION IN PATIENTS: RESULTS OF THE LOW DOSE PHASE.: 635

M. Cuesta, C. Hack, S. Meijer, 1997 .

The Arginine/ADMA Ratio Is Related to the Prevention of Atherosclerotic Plaques in Hypercholesterolemic Rabbits When Giving a Combined Therapy with Atorvastatine and Arginine

P. V. van Leeuwen, M. Richir, L. Cynober, 2015, International journal of molecular sciences.

Asymmetric dimethylarginine and critical illness

P. V. van Leeuwen, Saskia J H Brinkmann, Myrte C de Boer, 2013, Current opinion in clinical nutrition and metabolic care.

Nutrition before and during Surgery and the Inflammatory Response of the Heart: A Randomized Controlled Trial

B. D. de Mol, W. Kok, H. Niessen, 2015, Journal of nutrition and metabolism.

Ultrasound-Guided Percutaneous Transhepatic Cholangiography and Drainage in Patients with Hilar Cholangiocarcinoma

H. Nijs, P. V. van Leeuwen, O. Terpstra, 1990, Seminars in liver disease.

The effect of rosiglitazone on asymmetric dimethylarginine (ADMA) in critically ill patients.

G. Van den Berghe, A. Girbes, B. Ellger, 2009, Pharmacological research.

Organ blood flow after partial hepatectomy in rats: modification by endotoxin-neutralizing bactericidal/permeability-increasing protein (rBPI23).

M. Boermeester, C. V. van Noorden, P. V. van Leeuwen, 1999, Journal of hepatology.

Laparoscopic versus conventional Nissen fundoplication: the influence on plasma insulin-like growth factor-I and insulin-like growth factor binding protein-3.

M. Cuesta, P. V. van Leeuwen, M. Wiezer, 1999, International Journal of Surgical Investigation.

Taurine Concentrations Decrease in Critically Ill Patients With Shock Given Enteral Nutrition.

P. V. van Leeuwen, H. O. Oudemans-van Straaten, A. Houdijk, 2016, JPEN. Journal of parenteral and enteral nutrition.

Tumor necrosis factor unresponsiveness after surgery in bile duct-ligated rats.

M. Boermeester, C. Hack, P. V. van Leeuwen, 1996, The American journal of physiology.

PHARMACOKINETICS OF A RECOMBINANT AMINO TERMINAL FRAGMENT OF BACTERICIDAL/PERMEABILITY INCREASING PROTEIN (rBPI21) AFTER LIVER SURGERY IN RATS AND HUMANS

L. Thijs, P. V. van Leeuwen, M. Wiezer, 1998, Shock.

Endotoxin and interleukin‐1 related hepatic inflammatory response promotes liver failure after partial hepatectomy

M. Boermeester, W. Frederiks, P. V. van Leeuwen, 1995, Hepatology.

Immunological Consequences of Laparoscopic versus Open Transhiatal Resection for Malignancies of the Distal Esophagus and Gastroesophageal Junction

M. Cuesta, G. Ligthart-Melis, P. G. Boelens, 2008, Digestive Surgery.

Glutamine reduces phorbol-12,13-dibutyrate-induced macromolecular hyperpermeability in HT-29Cl.19A intestinal cells.

P. V. van Leeuwen, A. Houdijk, J. Groot, 1999, JPEN. Journal of parenteral and enteral nutrition.

Pretreatment with Enteral Cholestyramine Prevents Suppression of the Cellular Immune System After Partial Hepatectomy

M. Boermeester, M. Cuesta, D. Wilmore, 1995, Annals of Surgery.

Adjuvant treatment of early-stage melanoma by local i.d. administration of low-dose CpG-B and GM-CSF increases recurrence-free survival: long-term follow-up of three randomized clinical trials

T. D. de Gruijl, P. V. van Leeuwen, R. Scheper, 2015, Journal of Immunotherapy for Cancer.

Glutamine-enriched enteral nutrition increases HLA-DR expression on monocytes of trauma patients.

J. Puyana, L. Thijs, P. G. Boelens, 2002, The Journal of nutrition.

The prominent role of the liver in the elimination of asymmetric dimethylarginine (ADMA) and the consequences of impaired hepatic function.

M. Siroen, P. V. van Leeuwen, T. Teerlink, 2008, JPEN. Journal of parenteral and enteral nutrition.

Intralesional Cryotherapy for Treatment of Keloid Scars: A Prospective Study

P. V. van Zuijlen, M. V. D. van der Wal, P. V. van Leeuwen, 2015, Plastic and reconstructive surgery.

Reply: Intralesional Cryotherapy for the Treatment of Keloid Scars: A Prospective Study.

P. V. van Zuijlen, M. V. D. van der Wal, P. V. van Leeuwen, 2015, Plastic and reconstructive surgery.

Glutamine-enriched enteral nutrition increases HLA-DR expression on monocytes of trauma patients.

J. Puyana, L. Thijs, P. G. Boelens, 2002, The Journal of nutrition.

Role of dimethylarginine dimethylaminohydrolase activity in regulation of tissue and plasma concentrations of asymmetric dimethylarginine in an animal model of prolonged critical illness.

G. Van den Berghe, M. Davids, B. Ellger, 2012, Metabolism: clinical and experimental.

The gut does not contribute to systemic ammonia release in humans without portosystemic shunting.

C. Dejong, N. Deutz, G. Ligthart-Melis, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Cardiac surgery-specific screening tool identifies preoperative undernutrition in cardiac surgery.

B. D. de Mol, P. V. van Leeuwen, R. de Vos, 2013, The Annals of thoracic surgery.