A. Hasegawa

发表

Induction of an endogenous tumor necrosis factor in mice by murine recombinant interferon-γ combined with a lipid A subunit analog (GLA-60) of low toxicity

I. Saiki, H. Maeda, T. Sakurai, 2004, Cancer Immunology, Immunotherapy.

Characterization of high-affinity binding between gangliosides and amyloid beta-protein.

T. Miyatake, M. Kiso, A. Hasegawa, 2001, Archives of biochemistry and biophysics.

Regioselective a(2?3)-Sialylation of Le and Le by Sialidase-Catalyzed Transglycosylation

M. Kiso, A. Hasegawa, H. Ishida, 1998 .

Synthetic Studies on Sialoglycoconjugates. Part 101. Regioselective α(2→3)‐Sialylation of LeX and Lea by Sialidase‐Catalyzed Transglycosylation.

M. Kiso, A. Hasegawa, H. Ishida, 1998 .

Sulphatide binds to human and animal influenza A viruses, and inhibits the viral infection.

Y. Kawaoka, T. Ito, M. Kiso, 1996, The Biochemical journal.

Structural requirements for the carbohydrate ligand of E-selectin.

M. Kiso, A. Hasegawa, B. Brandley, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Adhesion of human cancer cells to vascular endothelium mediated by a carbohydrate antigen, sialyl Lewis A.

R. Kannagi, A. Hasegawa, K. Ohmori, 1991, Biochemical and biophysical research communications.

Binding Specificities of the Sialoadhesin Family of I-type Lectins

M. Kiso, A. Hasegawa, R. Schnaar, 1997, The Journal of Biological Chemistry.

Selectin-ligand interactions revealed by molecular dynamics simulation in solution.

H. Kondo, M. Kiso, A. Hasegawa, 1997, Journal of medicinal chemistry.

Glycan specificity of myelin-associated glycoprotein and sialoadhesin deduced from interactions with synthetic oligosaccharides.

N. Bovin, M. Kiso, A. Hasegawa, 1998, European journal of biochemistry.

Valency dependent patterns of binding of human L-selectin toward sialyl and sulfated oligosaccharides of Le(a) and Le(x) types: relevance to anti-adhesion therapeutics.

M. Kiso, A. Hasegawa, C. Galustian, 1997, Biochemistry.

Specificity of sialyl-sugar chain mediated recognition by the hemagglutinin of human influenza B virus isolates.

M. Kiso, A. Hasegawa, Y. Suzuki, 1994, Journal of biochemistry.

SequenceMarker of Dysplasia in the Colonic Adenoma-Carcinoma Sialyl Lewisx Antigen as Defined by Monoclonal Antibody AM-3

C. Hanski, F. Hanisch, A. Hasegawa, 2013 .

A Total Synthesis of Sialyl Dimeric Lex Ganglioside1

M. Kiso, A. Hasegawa, H. Ishida, 1995 .

Sialyl Lewis(x) antigen as defined by monoclonal antibody AM-3 is a marker of dysplasia in the colonic adenoma-carcinoma sequence.

C. Hanski, F. Hanisch, A. Hasegawa, 1992, Cancer research.

Structure-function studies on selectin carbohydrate ligands. Modifications to fucose, sialic acid and sulphate as a sialic acid replacement.

M. Kiso, A. Hasegawa, Y. Oda, 1993, Glycobiology.

Neuronal expression of a minor monosialosyl ganglioside GM1b in rat brain: immunochemical characterization using a specific monoclonal antibody

T. Hashikawa, A. Hasegawa, Y. Hirabayashi, 1995, Neuroscience Research.

Analysis of oligosaccharides of human IgG from serum of leukemia patients.

M. Kiso, A. Hasegawa, A. Kondo, 1994, Biochemistry and molecular biology international.

Sulfated blood group Lewis(a). A superior oligosaccharide ligand for human E-selectin.

K. Nicolaou, M. Kiso, A. Hasegawa, 1994, The Journal of biological chemistry.

Ganglioside GD1 alpha in cerebellar Purkinje cells. Its specific absence in mouse mutants with Purkinje cell abnormality and altered immunoreactivity in response to conjunctive stimuli causing long-term desensitization.

T. Hashikawa, A. Hasegawa, K. Sudo, 1994, The Journal of biological chemistry.

Sulfated sialyl Lewis X, the putative L-selectin ligand, detected on endothelial cells of high endothelial venules by a distinct set of anti-sialyl Lewis X antibodies.

R. Kannagi, M. Kiso, A. Hasegawa, 1997, Biochemical and biophysical research communications.

Inhibitory action of sulfatide, a putative ligand for L-selectin, on B cell proliferation and Ig production.

T. Miyawaki, M. Kiso, A. Hasegawa, 1996, International immunology.

Studies on Selectin Binding Inhibitors: Synthesis of Sialyl-Lewis X and Sialyl-Lewis A Epitope Analogs Containing 2-Acetamido Derivative of N-Methyl-1-Deoxynojirimycin1

M. Kiso, A. Hasegawa, H. Ishida, 1996 .

Synthetic Studies on Tumor-Associated Antigens: Efficient Syntheses of Lea and Sialyl-Lea Oligosaccharides, and Their Deaminated Analogs1

M. Kiso, A. Hasegawa, H. Ishida, 1996 .

Studies on selectin blocker. 1. Structure-activity relationships of sialyl Lewis X analogs.

H. Kondo, Y. Inoue, K. Yoshino, 1996, Journal of medicinal chemistry.

Studies on selectin blockers. 2. Novel selectin blocker as potential therapeutics for inflammatory disorders.

H. Kondo, K. Yoshino, M. Kiso, 1996, Journal of medicinal chemistry.

Antimetastatic effect of endogenous tumor necrosis factor induced by the treatment of recombinant interferon γ followed by an analogue (GLA-60) to synthetic lipid A subunit

I. Saiki, H. Maeda, J. Murata, 2005, Cancer Immunology, Immunotherapy.

Induction of differentiation of human monoblastic and myeloblastic leukemia cell lines by TNF muteins.

M. Ikehara, K. Inaka, K. Takeda, 1989, Biochemical and biophysical research communications.

Multistep regulation mechanisms for tolerance induction to lipopolysaccharide lethality in the tumor‐necrosis‐factor‐α‐mediated pathway

M. Kiso, A. Hasegawa, M. Nakano, 1994 .

A distinct type of sialyl Lewis X antigen defined by a novel monoclonal antibody is selectively expressed on helper memory T cells.

R. Kannagi, M. Kannagi, M. Kiso, 1993, Blood.

Differentiation-dependent expression of sialyl stage-specific embryonic antigen-1 and I-antigens on human lymphoid cells and its implications for carbohydrate-mediated adhesion to vascular endothelium.

R. Kannagi, A. Hasegawa, K. Hirashima, 1993, Blood.

The vascular E-selectin binds to the leukocyte integrins CD11/CD18.

C. Gahmberg, D. Altieri, M. Kiso, 1993, Glycobiology.

Reversal of lipopolysaccharide-analog-induced antibody suppression by anti-transforming growth factor beta and indomethacin

A. Hasegawa, M. Mohrman, A. Johnson, 1995, Infection and immunity.

Synthetic and structural studies of α-sialyl-(2 → 6) and α-sialyl-(2 → 3) 1-deoxynojirimycin derivatives potentially useful for biomedical applications☆

M. Kiso, A. Hasegawa, H. Ishida, 1995 .

Systematic synthesis of N-methyl-1-deoxynojirimycin-containing, Le(x), Le(a), sialyl-Le(x) and sialyl-Le(a) epitopes recognized by selectins.

M. Kiso, A. Hasegawa, H. Ishida, 1994, Bioorganic & medicinal chemistry.

Induction of programmed cell death and immunosuppression by exogenous sphingolipids are separate processes.

A. Hasegawa, S. Ladisch, R. Olshefski, 1996, European journal of biochemistry.

Synthetic Studies on Sialoglycoconjugates 61: Synthesis of α-Series Ganglioside GM1α

M. Kiso, A. Hasegawa, H. Ishida, 1994 .

Synthesis of disialoganglioside GD1α and its positional isomer

M. Kiso, A. Hasegawa, H. Prabhanjan, 1992 .

Regio- and stereo-selective synthesis of ganglioside GM1b and some positional analogs.

M. Kiso, A. Hasegawa, A. Kameyama, 1991, Carbohydrate research.

Synthesis, structures, and magnetic properties of dicopper(II) and dinickel(II) complexes with a new bis(macrocycle), 7,7′-(2-hydoxypropane-1,3-diyl)bis{3,7,11,17-tetraazabicyclo[11.3.1]- heptadeca-1(17),13,15-triene} ☆

A. Hasegawa, T. Weyhermüller, K. Mochizuki, 2004 .

Activity of Monosaccharide Lipid A Analogues in Human Monocytic Cells as Agonists or Antagonists of Bacterial Lipopolysaccharide

M. Kiso, A. Hasegawa, M. Matsuura, 1999, Infection and Immunity.

Sphingolipids are essential for the growth of Chinese hamster ovary cells. Restoration of the growth of a mutant defective in sphingoid base biosynthesis by exogenous sphingolipids.

M. Kiso, A. Hasegawa, K. Hanada, 1992, The Journal of biological chemistry.

Sialidase of swine influenza A viruses: variation of the recognition specificities for sialyl linkages and for the molecular species of sialic acid with the year of isolation

M. Kiso, A. Hasegawa, Yasuo Suzuki, 1995, Glycoconjugate Journal.

Synthesis of the alpha-Neu5Ac-(2----6)-Gal structure. Facile 6-O-sialylation following stannylene activation of an unprotected D-galactopyranoside.

M. Kiso, A. Hasegawa, K. Kartha, 1989, Carbohydrate research.

High affinity antibodies against Lex and sialyl Lex from a phage display library.

N. Weng, M. Kiso, A. Hasegawa, 1996, Journal of immunology.

Functional role of sialyl Lewis X and fibronectin‐derived RGDS peptide analogue on tumor‐cell arrest in lungs followed by extravasation

H. Tsukada, I. Saiki, J. Murata, 1996, International journal of cancer.

Differential effect of various inhibitors on four types of rat sialidase

T. Aoyagi, A. Hasegawa, T. Miyagi, 1993, Glycoconjugate Journal.

Structural requirements of muramylpeptides for induction of necrosis at sites primed with Mycobacterium tuberculosis in guinea pigs

M. Kiso, A. Hasegawa, S. Kusumoto, 1987, Infection and immunity.

Synthesis of a sialyl Lewis X ganglioside analogue containing N-glycolyl in place of the N-acetyl group in the N-acetylneuraminic acid residue.

M. Kiso, A. Hasegawa, H. Ishida, 1995, Bioscience, biotechnology, and biochemistry.

Synthetic Studies on Sialoglycoconjugates 70: Synthesis of Sialyl and Sulfo Lewis × Analogs Containing a Ceramide or 2-(Tetradecyl)hexadecyl Residue

M. Kiso, A. Hasegawa, H. Ishida, 1995 .

Synthetic Studies on Sialoglycoconjugates 23: Total Synthesis of Sialyl-α(2↠6)-Lactotetraosylceramide and Sialyl-α(2↠6)-Neolactotetraosylceramide

M. Kiso, A. Hasegawa, H. Ishida, 1991 .

Stereoselective synthesis of sialyl-lactotetraosylceramide and sialylneolactotetraosylceramide.

M. Kiso, A. Hasegawa, A. Kameyama, 1990, Carbohydrate research.

SYNTHETIC STUDIES ON SELECTIN LIGANDS/INHIBITORS : A SYSTEMATIC SYNTHESIS OF SULFATIDE AND ITS HIGHER CONGENERS CARRYING 2-(TETRADECYL)HEXADECYL GROUP AS A CERAMIDE SUBSTITUTE

M. Kiso, A. Hasegawa, H. Ishida, 1997 .

Gangliosides are neuronal ligands for myelin-associated glycoprotein.

M. Kiso, A. Hasegawa, R. Schnaar, 1996, Proceedings of the National Academy of Sciences of the United States of America.

In vitro and in vivo selectin-blocking activities of sulfated lipids and sulfated sialyl compounds.

P. Ward, M. Kiso, A. Hasegawa, 1998, International immunology.

An Unusual Behavior of Methyl or Benzyl 3-Azido-5-O-Benzoyl-3,6-Di-Deoxy-α-L-Talofuranoside with (Dimethylamino)Sulfur Trifluoride; Migration of the Alkoxyl Group from the C-1 to the C-2 Position

M. Kiso, A. Hasegawa, M. Goto, 1985 .

Synthetic Studies on Sialoglycoconjugates 95: Total Synthesis of Sulfated Glucuronyl Lactosaminyl Paraglobosides

M. Kiso, A. Hasegawa, H. Ishida, 1996 .

Carbohydrates : synthetic methods and applications in medicinal chemistry

A. Hasegawa, 小倉治夫, 須網哲夫, 1992 .

An Efficient Structural Analysis of N-Methyl-1-deoxynojirimycin-Containing Sialo-oligosaccharides by Ion-Spray Mass Spectrometry and the Mechanism of Palladium Catalyzed N-Methylation in Methanol1

M. Kiso, A. Hasegawa, H. Ishida, 1994 .

Fluorination of methyl 6-deoxy-1-thiohexopyranosides with diethylaminosulfur trifluoride (DAST), and the formation of unexpected products

M. Kiso, A. Hasegawa, H. Ishida, 1993 .

Synthesis of kasuganobiosamine

A. Hasegawa, Shozo Takahashi, K. Kitahara, 1968 .

A highly practical synthesis of the sialyl Lewis X pentasaccharide and an investigation of binding to E-, P-, and L-selectins.

H. Kondo, M. Kiso, A. Hasegawa, 1996, Bioorganic & medicinal chemistry.

A facile, large-scale preparation of the methyl 2-thioglycoside of N-acetylneuraminic acid, and its usefulness for the alpha-stereoselective synthesis of sialoglycosides.

M. Kiso, A. Hasegawa, H. Ishida, 1991, Carbohydrate research.

Acetonation of 2-(acylamino)-2-deoxy-d-glucoses☆

M. Kiso, A. Hasegawa, 1978 .

Synthesis of deoxygalactose-containing sialyl LeX ganglioside analogues to elucidate the structure necessary for selectin recognition

M. Kiso, A. Hasegawa, H. Ishida, 1996, Glycoconjugate Journal.

Synthetic Studies on Sialoglycoconjugates 16: α-Predominant Glycoside Synthesis of N-Acetylneuraminic Acid With the Primary Hydroxyl Group in Carbohydrates Using Dimethyl(Methylthio)Sulfonium Triflate as a Glycosyl Promoter

M. Kiso, A. Hasegawa, H. Ishida, 1990 .

Synthetic Studies on Sialoglycoconjugates 9: An Efficient Method for the Selective Acetolysis of 2-(Trimethylsilyl)Ethyl Glycosides Using Ferric Chloride in Acetic Anhydride

M. Kiso, A. Hasegawa, K. Kartha, 1989 .

NOVEL SELECTIVITY IN CARBOHYDRATE REACTIONS. III. SELECTIVE DEPROTECTION OF P-METHOXYBENZYL (PMBN) ETHERS OF CARBOHYDRATES BY TIN(IV)CHLORIDE

M. Kiso, A. Hasegawa, H. Jennings, 1998 .

Synthesis of 2,4-di-O-benzyl-3-deoxy-3-(N-(2,4-dinitrophenyl)-N-methylamino)-alpha-D-xylopyranosyl chloride (a 1-halogeno gentosamine derivative).

M. Kiso, A. Hasegawa, 1975, Carbohydrate research.

Synthesis of N-trifluoroacetyl-L-acosamine, N-trifluoroacetyl-L-daunosamine, and their 1-thio analogs.

R. Whistler, A. Hasegawa, I. Pelyvás, 1986, Carbohydrate research.

Biological activities of chemically synthesized analogues of the nonreducing sugar moiety of lipid A

M. Kiso, A. Hasegawa, M. Matsuura, 1984, FEBS letters.

Synthesis of a novel series of 4-O-phosphono-d-glucosamine derivatives (lipid A subunit analogs) carrying the C-branched 2-tetradecylhexadecanoyl group

Y. Ogawa, M. Kiso, A. Hasegawa, 1991 .

Synthesis of the optically active 4-O-phosphono-D-glucosamine derivatives related to the nonreducing-sugar subunit of bacterial lipid A.

Y. Ogawa, M. Kiso, A. Hasegawa, 1987, Carbohydrate research.

A new synthetic route to 2-(acylamino)-2-deoxy-alpha-D-glucopyranosyl phosphates, and their endotoxic activity related to the Salmonella-type lipid A.

M. Kiso, A. Hasegawa, I. Azuma, 1981, Carbohydrate research.

Nonreducing-Sugar Subunit Analogs of Bacterial Lipid a Carrying the Ester-Bound (3R)-3-(Acyloxy)Tetradecanoyl Group

Shinji Tanaka, Y. Ogawa, M. Kiso, 1987 .

Synthetic Studies on Sialoglycoconjugates 90: Total Synthesis of Sulfated Glucuronyl Paraglobosides

M. Kiso, A. Hasegawa, H. Ishida, 1996 .

A new synthetic route to 2-amino-2-deoxy-d-mannose derivatives from 3,4:5,6-di-O-isopropylidene-aldehydo-d-glucose dibenzyl acetal

M. Kiso, A. Hasegawa, H. Ishida, 1984 .

One-flask synthesis of triacetalated aldohexoses with 2,2-dialkoxypropane and p-toluenesulfonic acid

M. Kiso, A. Hasegawa, A. Kondo, 1984 .

Total synthesis of sialyl lactotetraosyl ceramide

M. Kiso, A. Hasegawa, H. Ishida, 1989 .

Synthetic Studies on Sialoglycoconjugates. 5: A Facile, Regio and Stereoselective Synthesis of Ganglioside GM4 and Its Position Isomer1

M. Kiso, A. Hasegawa, H. Ishida, 1989 .

Chemical combination of 6-deoxy-6-mycoloylamino-α,α-trehalose and N-acetyl-6-O-(aminoacyl)muramoyl dipeptide

Y. Ogawa, T. Sakurai, M. Kiso, 1989 .

Application of ferric chloride-catalyzed glycosylation to a synthesis of glycolipids

M. Kiso, A. Hasegawa, Hisao Nishiguchi, 1980 .

A New Synthetic Method of Preparing Iodohydrin and Bromohydrin Derivatives through in situ Generation of Hypohalous Acids from H5IO6 and NaBrO3 in the Presence of NaHSO3

A. Hasegawa, Y. Ishii, Y. Nishiyama, 1994 .

A simple preparation of 2-(acylamino)-2-deoxy-3,4:5,6-di-O-isopropylidene-aldehydo-d-glucose dimethyl and dibenzyl acetal

M. Kiso, A. Hasegawa, 1980 .

Acetonation of some pentoses with 2,2-dimethoxypropane-N,N-dimethylformamide-p-toluenesulfonic acid☆

M. Kiso, A. Hasegawa, 1976 .

Induction of tumoricidal macrophages and production of cytokines by synthetic muramyl dipeptide analogues.

I. Saiki, J. Murata, J. Iida, 1988, Vaccine.

Synthesis of sialyl LeX ganglioside analogues modified at C-6 of the galactose residue to elucidate the mechanism of selection recognition.

M. Kiso, A. Hasegawa, H. Ishida, 1998, Carbohydrate research.

First total synthesis of ganglioside GT1aα

Hiromi Ito, M. Kiso, A. Hasegawa, 1997 .

Synthesis of 6'-GM2, a regioisomer of ganglioside GM2, for studying the mechanism of action of GM2 activator.

M. Kiso, A. Hasegawa, H. Ishida, 1997, Carbohydrate research.

Synthetic Studies on Sialoglycoconjugates 91: Total Synthesis of Gangliosides GD1C and GT1A

Hiromi Ito, M. Kiso, A. Hasegawa, 1997 .

Total synthesis of VIM-2 ganglioside isolated from human chronic myelogenous leukemia cells.

Y. Yamada, M. Kiso, A. Hasegawa, 1996, Carbohydrate research.

Protective activity of lipid A analogue GLA‐60 against murine cytomegalovirus infection in mice

E. De Clercq, S. Ikeda, J. Neyts, 1993, Journal of medical virology.

Adjuvant activities of synthetic lipid A subunit analogues and its conjugates with muramyl dipeptide derivatives.

I. Saiki, H. Maeda, M. Kiso, 1989, Vaccine.

Enhancement of immunoglobulin G responses in mice against hepatitis B virus surface antigen, influenza virus hemagglutinin vaccine, and tetanus toxoid by 6-O-acylated muramyl dipeptides

M. Kiso, A. Hasegawa, Y. Kumazawa, 1989, Infection and immunity.

Synthesis Of 2-Acetamido-2-Deoxy-5-Thio-α-D-Galactopyranose

M. Kiso, A. Hasegawa, E. Tanahashi, 1983 .

Studies on Glycan Processing Inhibitors: Synthesis of N- Acetylhexosamine Analogs and Cyclic Carbamate Derivatives of 1- Deoxynojirimycin.

M. Kiso, A. Hasegawa, H. Ishida, 1991 .

Substrate specificity of the Trypanosoma cruzi trans-sialidase.

V. Nussenzweig, M. Kiso, A. Hasegawa, 1992, Glycobiology.

Synthetic Studies on Sialoglycoconjugates 14: Synthesis of Ganglioside GM3 Analogs Containing The Carbon 7 And 8 Sialic Acids

M. Kiso, A. Hasegawa, M. Morita, 1990 .

Studies on the Thioglycosides of N-Acetylneuraminic Acid 7: Synthesis of S-(α-Sialyl)-(2↠6)-β-D-Hexopyranosyl and -(2↠6)-β-D-Lactosyl Ceramides and their Biological Activity

M. Kiso, A. Hasegawa, M. Morita, 1990 .

Synthetic Studies on Sialoglycoconjugates. 3: Synthesis of 5-Acetamido-3,5-Dideoxy-l-Arabino-2-Heptulosonic Acid Derivatives and Analogs

M. Kiso, A. Hasegawa, H. Ishida, 1989 .

Synthesis of 3-S-C (5-Acetamido-3.5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic Acid)-3-thio-galactopyranose Derivatives

M. Kiso, A. Hasegawa, Osamu Kanie, 1987 .

Synthesis of prumycin and related compounds.

M. Kiso, A. Hasegawa, N. Aritake, 1976, Carbohydrate Research.

A new synthesis of prumycin.

M. Kiso, A. Hasegawa, N. Aritake, 1976, Carbohydrate research.

Synthesis of 2,4-Diamino-2,4-dideoxy-l-arabinose Derivatives (Prumycin Derivatives)†

M. Kiso, A. Hasegawa, T. Sakurai, 1978 .

The behavior of some aldoses with 2,2-dialkoxypropane-N,N-dimethylformamide-toluene-p-sulphonic acid

A. Hasegawa, T. Sakurai, Noboru Hasegawa, 1975 .

Communication: Synthetic Studies on Sialoglycoconjugates 25: Reactivity of Glycosyl Promoters in α-Glycosylation of N-Acetyl-Neuraminic Acid with the Primary and Secondary Hydroxyl Groups in the Suitably Protected Galactose and Lactose Derivatives

M. Kiso, A. Hasegawa, H. Ishida, 1991 .

Synthesis of the methyl thioglycosides of 2-, 3-, and 4-deoxy-L-fucose.

T. Ando, M. Kiso, A. Hasegawa, 1994, Carbohydrate research.

A facile regio- and stereo-selective synthesis of α-glycosides of N-acetylneuraminic acid

M. Kiso, A. Hasegawa, H. Ishida, 1988 .

Glycosylation Using Methylthioglycosides of N-Acetylneuraminic Acid and Dimethyl(Methylthio)Sulfonium Triflate

M. Kiso, A. Hasegawa, Osamu Kanie, 1988 .

Synthetic Studies on Sialoglycoconjugates 59: Total Synthesis of Tumor-Associated Ganglioside, Sialyl Le

M. Kiso, A. Hasegawa, H. Ishida, 1991 .

Synthetic Studies on Sialoglycoconjugates 40: Stereocontrolled Synthesis of Sialyl Lewis X Epitope and Its Ceramide Derivative

M. Kiso, A. Hasegawa, T. Ando, 1992 .

Stereocontrolled synthesis of sialyl Lewis X ceramide consisting of a pentasaccharide recognized by the selectin family.

M. Kiso, A. Hasegawa, T. Ando, 1992, Carbohydrate Research.

Synthesis of carbohydrate analogs (positional, configurational, and optical) of n-acetylmuramoyl-L-alanyl-D-isoglutamine, and their immunoadjuvant activities.

M. Kiso, A. Hasegawa, I. Azuma, 1981, Carbohydrate research.

A general, convenient synthesis of the repeating, disaccharide—dipeptide unit of the bacterial, cell-wall peptidoglycan by the oxazoline method☆

M. Kiso, A. Hasegawa, Yoshimi Kaneda, 1980 .

Synthesis and immunoadjuvant activities of the repeating, disaccharide-dipeptide unit of the bacterial, cell-wall peptidoglycan and of some carbohydrate analogs.

M. Kiso, A. Hasegawa, I. Azuma, 1982, Carbohydrate Research.

Total synthesis of sialyl Lewis X.

M. Kiso, A. Hasegawa, H. Ishida, 1991, Carbohydrate research.

Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endothelium.

R. Kannagi, M. Kiso, A. Hasegawa, 1993, Cancer research.

The three members of the selectin receptor family recognize a common carbohydrate epitope, the sialyl Lewis(x) oligosaccharide

S. Watson, D. Dowbenko, L. Lasky, 1992, The Journal of cell biology.

Specificity of the N1 and N2 sialidase subtypes of human influenza A virus for natural and synthetic gangliosides.

M. Kiso, A. Hasegawa, G. Hanagata, 1998, Glycobiology.

Synthesis and biological activity of O-(N-acetyl-β-muramoyl-l-alanyl-d-isoglutamine)-(1→6)-2-acylamino-2-deoxy-d-glucoses☆

M. Kiso, A. Hasegawa, I. Azuma, 1982 .

Synthesis of β-d-(1→6)-linked disaccharides of N-fatty acylated 2-amino-2-deoxy-d-glucose: an approach to the lipid a component of the bacterial lipopolysaccharide

M. Kiso, A. Hasegawa, I. Miura, 1981 .

New ganglioside analogs that inhibit influenze virus sialidase

M. Kiso, A. Hasegawa, Yasuo Suzuki, 2005, Glycoconjugate Journal.

Synthesis of N-acetyl-4,8-dideoxyneuraminic acid-containing ganglioside GM3.

M. Kiso, A. Hasegawa, H. Ishida, 1996, Carbohydrate research.

Synthesis of ganglioside analogs containing sulfur in place of oxygen at the linkage positions.

M. Kiso, A. Hasegawa, H. Ishida, 1994, Methods in enzymology.

Synthesis of a series of ganglioside GM3 analogs containing a deoxy-N-acetylneuraminic acid residue.

M. Kiso, A. Hasegawa, K. Adachi, 1992, Carbohydrate research.

Synthesis of a position isomer of ganglioside GD3having an α-Neu5Ac-(2→9)-α-Neu5Ac linkage

M. Kiso, A. Hasegawa, H. Ogawa, 1992 .

Synthesis of an S-(alpha-sialosyl)-(2----9)-O-(alpha-sialosyl)-(2----3')-beta-lactos ylceramide.

M. Kiso, A. Hasegawa, H. Ishida, 1992, Carbohydrate research.

Synthesis of cerebroside, lactosyl ceramide, and ganglioside GM3 analogs containing beta-thioglycosidically linked ceramide.

M. Kiso, A. Hasegawa, M. Morita, 1991, Carbohydrate research.

Studies on the Thioglycosides of N-Acetyl-Neuraminic Acid 8: Synthesis of S-(α-Sialyl)-(2→ 6)-β-Hexopyranosyl and -(2→ 6')-β-Lactosyl Ceramides Containing β-Thioglycosidically Linked Ceramide

M. Kiso, A. Hasegawa, H. Ogawa, 1991 .

Synthetic Studies on Sialoglycoconjugates 12: Total Synthesis of Sialyl Neolactotetraosyl Ceramide

M. Kiso, A. Hasegawa, H. Ishida, 1989 .

A facile, regio- and stereo-selective synthesis of ganglioside GM3.

M. Kiso, A. Hasegawa, H. Ishida, 1989, Carbohydrate research.

Studies on the Thioglycosides of N-Acetylneuraminic Acid. 6: Synthesis of Ganglioside GM4 Analogs1

M. Kiso, A. Hasegawa, Yuki Ito, 1989 .

Synthetic Studies Toward Gangliosides and Their Analogs: Synthesis of Appropriately Protected Core Oligosaccharides as Construction Blocks

M. Kiso, A. Hasegawa, A. Kameyama, 1989 .

Stereoselective Synthesis of 5′-S-(5-Acetamido-3,5-dideoxy-D-glycero-α-and-β-D-Galacto-2-nonulopyranosylonic Acid)-5′-thio Cytidixe

M. Kiso, A. Hasegawa, Osamu Kanie, 1987 .

A novel route to D-erythro-sphingosine and related compounds from mono-O-isopropylidene-D-xylose or -D-galactose

M. Kiso, A. Hasegawa, Y. Tomita, 1986 .

Studies on the Thioglycosides of N-Acetylneuraminic Acid 1: Synthesis of Alkyl α-Glycosides of 2-Thio-N-Acetylneuraminic Acid

M. Kiso, A. Hasegawa, J. Nakamura, 1986 .

Synthetic Studies on Sialoglycoconjugates 88: Synthesis of Ganglioside GM3 and GM4 Analogs Containing 2- OR 3-Branched Fatty-Alkyl Residues in Place of Ceramide

M. Kiso, A. Hasegawa, N. Suzuki, 1996 .

Synthetic Studies on Sialoglycoconjugates 66: First Total Synthesis of a Cholinergic Neuron-Specific Ganglioside GQ1bα1

M. Kiso, A. Hasegawa, H. Ishida, 1995 .

Synthetic Studies on Sialoglycoconjugates 54: Synthesis of I-Active Ganglioside Analog

M. Kiso, A. Hasegawa, H. Ishida, 1994 .

Synthesis of ganglioside GM3 and analogs containing modified sialic acids and ceramides.

M. Kiso, A. Hasegawa, 1994, Methods in enzymology.

Synthetic Studies on Sialoglycoconjugates 31: Synthesis of Ganglioside GM3 Analogs Containing the Chemically Modified Sialic Acids

M. Kiso, A. Hasegawa, Masahiro Yoshida, 1992 .

Total synthesis of a disialoganglioside GD1α

M. Kiso, A. Hasegawa, H. Prabhanjan, 1991 .

A facile total synthesis of ganglioside GM1b and its positional analog.

M. Kiso, A. Hasegawa, H. Ishida, 1991, Carbohydrate research.

Synthesis of chemically modified sialic acid-containing sialyl-LeX ganglioside analogues recognized by the selectin family

M. Kiso, A. Hasegawa, Masahiro Yoshida, 1993, Glycoconjugate Journal.

Synthesis of the methyl thioglycosides of deoxy-N-acetyl-neuraminic acids for use as glycosyl donors.

M. Kiso, A. Hasegawa, K. Adachi, 1992, Carbohydrate research.

Synthetic Studies on Sialoglycoconjugates 18: Synthesis of 7-O-, 7,9-Di-O-, and 7,8,9-Tri-O-Acetyl-N-Acetyl-Neuraminic Acid Derivatives

M. Kiso, A. Hasegawa, H. Ishida, 1990 .

Synthetic Studies on Sialoglycoconjugates 17: Synthesis of 4-O-, 9-O-, and 4,9-Di-O-Acetyl-N-Acetylneuraminic Acids and their Derivatives

M. Kiso, A. Hasegawa, H. Ishida, 1990 .

Synthesis of 6-S-(5-Acetamido-3,5-Dideoxy-D-Glycero-α-D-Galacto-2-Nonulopyranosylonic Acid)-6-Thio-Hexopyranosides

M. Kiso, A. Hasegawa, J. Nakamura, 1986 .

Synthesis and biological activities of three sulfated sialyl Le(x) ganglioside analogues for clarifying the real carbohydrate ligand structure of L-selectin.

M. Kiso, A. Hasegawa, H. Ishida, 1996, Bioorganic & medicinal chemistry.

Syntheses of Paromamine and Its Related Compounds

A. Hasegawa, M. Nakajima, T. Kurokawa, 1972 .

Synthesis of sialyl Lewis X ganglioside and analogs.

M. Kiso, A. Hasegawa, 1994, Methods in enzymology.

Synthetic Studies on Sialoglycoconjugates 41: A Facile Total Synthesis of Ganglioside GM2

M. Kiso, A. Hasegawa, H. Ohki, 1992 .

Synthesis of 2,5-diacetamido-2,5-dideoxy- and 2,3,5-triacet-amido-2,3,5-Trideoxy-d-aldopentofuranose derivatives☆

M. Kiso, A. Hasegawa, N. Aritake, 1980 .

Synthesis of a 2-acetamido-5-amino-2,5-dideoxy-d-xylopyranosyl derivative

M. Kiso, A. Hasegawa, N. Aritake, 1980 .

Synthesis of a furanoid 2-aminoglycal derivative☆

M. Kiso, A. Hasegawa, 1979 .

Synthesis of 2-acetamido-2-deoxy-5-thio-d-glucopyranose

M. Kiso, A. Hasegawa, H. Kasugai, 1978 .

One-step synthesis of 2-acetamido-1,4-anhydro-2-deoxy-5,6-O-isopropylidene-D-arabino-hex-1-enitol, a furanoid, 2-aminoglycal derivative

M. Kiso, A. Hasegawa, 1977 .

Isopropylidenation with 2,2-dimethoxypropane-N,N-dimethylformamide-p-toluenesulfonic acid selective substitution in certain aminocyclitols

A. Hasegawa, M. Nakajima, 1973 .

Synthesis of 2-acetamido-2-deoxy-5-thio-α-d-mannopyranose☆

M. Kiso, A. Hasegawa, Y. Hioki, 1983 .

A facile synthesis of 2-acetamido-2-deoxy-5-thio-d-glucopyranose

M. Kiso, A. Hasegawa, E. Tanahashi, 1983 .

Reaction of some D-glucobioses with 2,2-dimethoxypropane

M. Kiso, A. Hasegawa, R. Yamauchi, 1981 .

Reaction of maltose with 2,2-dimethoxypropane

M. Kiso, A. Hasegawa, R. Yamauchi, 1981 .

Synthesis of 2-acetamido-5-amino-2,5-dideoxy-d-gluco- and -l-ido-pyranose derivatives☆

M. Kiso, A. Hasegawa, E. Tanahashi, 1980 .

Synthesis of sialyl Le(x) ganglioside analogues sulfated at C-6 of either the galactose or N-acetylglucosamine residues, and at both of the galactose and N-acetylglucosamine residues: probes for clarifying the real carbohydrate ligand of L-selectin.

M. Kiso, A. Hasegawa, H. Ishida, 1996, Carbohydrate research.

Systematic synthesis of α-sialyl-(2 → 3)- and -(2 → 6)-isoglobopentaosylceramides (V3 Neu5AciGb5Cer and V6Neu5AciGb5Cer)☆

M. Kiso, A. Hasegawa, H. Ishida, 1996 .

Synthetic Studies on Sialoglycoconjugates 82: First Total Synthesis of Sialyl Globopentaosyl Ceramide (V3Neu5AcGb5Cer) and its Positional Isomer (V6Neu5AcGb5Cer)1,2

M. Kiso, A. Hasegawa, H. Ishida, 1996 .

Synthetic Studies on Sialoglycoconjugates 74: Synthesis of KDN-gangliosides GM1, GM2, and GD1a

M. Kiso, A. Hasegawa, H. Ishida, 1995 .

Synthetic Studies on Sialoglycoconjugates 73: Synthesis of KDN-α-(2→6)-lactotetraosylceramide and KDN-α-(2→6)-neolactotetraosylceramide

M. Kiso, A. Hasegawa, H. Ishida, 1995 .

Synthetic Studies on Sialoglycoconjugates 72: Synthesis of Sulfo-, Phosphono- and Sialyl-Lewis × Analogs Containing the 1-Deoxy- and 1,2-Dideoxy-hexopyranoses in Place of N-Acetylglucosamine Residue

M. Kiso, A. Hasegawa, H. Ishida, 1995 .

Synthetic Studies on Sialoglycoconjugates 65: Stereocontrolled Synthesis of Positional Isomers of Tumor-Associated Ganglioside Antigens, Sialyl Lewis X and Sialyl Paragloboside

M. Kiso, A. Hasegawa, H. Ishida, 1995 .

Total synthesis of ganglioside GQ1b and the related polysialogangliosides

M. Kiso, A. Hasegawa, H. Ishida, 1994 .

Synthesis of 65-and/or 45-O-glycosyl p-nitrophenyl α-maltopentaoside derivatives for the differential assay of human α-amylases

M. Kiso, A. Hasegawa, H. Ishida, 1994 .

Total synthesis of ganglioside GQ1b.

M. Kiso, A. Hasegawa, H. Ishida, 1994, Carbohydrate research.

Synthetic Studies on Sialoglycoconjugates 60: α-Stereocontrolled, Glycoside Synthesis of Trimeric Sialic Acid with Galactose and Lactose Derivatives

M. Kiso, A. Hasegawa, H. Ishida, 1994 .

Synthesis of KDN-lactotetraosylceramide, KDN-neolactotetraosylceramide, and KDN-Lewis X ganglioside.

M. Kiso, A. Hasegawa, T. Terada, 1994, Carbohydrate research.

Synthetic Studies on Sialoglycoconjugates 53: Synthesis of Novel N-Methyl-1-Deoxynojirimycincontaining Sialo-Oligosaccharides Related to Ganglioside GM3 Active as a Biosignal Mediator

M. Kiso, A. Hasegawa, H. Ishida, 1994 .

A facile total synthesis of ganglioside GD2.

M. Kiso, A. Hasegawa, H. Ishida, 1994, Carbohydrate research.

Synthetic Studies on Sialoglycoconjugates 48: Total Synthesis of Gangliosides Gm1 and Gd1a

M. Kiso, A. Hasegawa, H. Ishida, 1993 .

A synthetic approach to polysialogangliosides containing alpha-sialyl-(2-->8)-sialic acid: total synthesis of ganglioside GD3.

M. Kiso, A. Hasegawa, H. Ishida, 1993, Carbohydrate research.

Synthetic Studies on Sialoglycoconjugates 44: Synthesis of KDN-Gangliosides Gm4 and GM3

M. Kiso, A. Hasegawa, T. Terada, 1993 .

Synthetic Studies on Sialoglycoconjugates 45: Synthesis of 1-Deoxynojirimycin-Containing Oligosaccharides Related to the Cancer-Associated Sialyl-Lewis a Antigen Recognized by Lec-Cams (Selectins)

M. Kiso, A. Hasegawa, H. Furui, 1993 .

A facile, systematic synthesis of ganglio-series gangliosides: total synthesis of gangliosides GM1 and GD1a.

M. Kiso, A. Hasegawa, T. Nagahama, 1992, Carbohydrate research.

Synthesis of 1-deoxynojirimycin-containing glycans related to the Lewis X and sialyl-Lewis X epitopes recognized by LEC-CAMs.

M. Kiso, A. Hasegawa, H. Furui, 1992, Carbohydrate research.

Synthetic Studies on Sialoglycoconjugates 37: Synthesis of Sialyl-α(2→6)-D-glucopyranosyl, 2-Acetamido-2-deoxyhexopyranosyl, and Sialyl-α(2→3)-2-acetamido-2-deoxy-D-glucopyranosyl Ceramide or the Analogs at the Lipophilic Part

M. Kiso, A. Hasegawa, M. Ogawa, 1992 .

Synthesis of alpha-Kdo-(2----4)-Kdo disaccharide derivatives and their conjugation with a protected form of GLA-60, a biologically active analog of a lipid A subunit.

Y. Ogawa, M. Kiso, A. Hasegawa, 1990, Carbohydrate research.

SYNTHETIC STUDIES ON SIALOGLYCOCONJUGATES 89 : SYNTHESIS OF GANGLIOSIDE GM3 AND KDN-GM3 CONTAINING DIFFERENT CARBON-CHAIN LENGTH FATTY ACYL GROUPS AT THE CERAMIDE RESIDUE

M. Kiso, A. Hasegawa, N. Suzuki, 1996 .

Immunosuppressive activity of chemically synthesized gangliosides.

M. Kiso, A. Hasegawa, S. Ladisch, 1995, Biochemistry.

A Chemically Synthesized Sialic Acid-Containing Glycoconjugate, 2-(tetradecylhexadecyl)-O-(5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic acid)-(2→3)-O-β-D-galactopyrannosyl-(1→4)-β-D-glucopyrannoside, Is a Potent Inhibitor of Cellular Immune Responses

Ruixiang Li, M. Kiso, A. Hasegawa, 1994 .

Systematic Synthesis of Sialoglycoconjugates “Gangliosides” Towards the Elucidation of their Biological Functions

M. Kiso, A. Hasegawa, 1992 .

Synthetic Studies on Sialoglycoconjugates 15: Synthesis of Ganglioside GM3 Analogs Containing A Variety Of Lipophilic Parts

M. Kiso, A. Hasegawa, M. Morita, 1990 .

Synthetic Studies on Sialoglycoconjugates. Part 55. Synthesis of the Methyl Thioglycosides of 2-, 3-, and 4-Deoxy-L-fucose.

T. Ando, M. Kiso, A. Hasegawa, 2010 .

Synthesis of the methyl thioglycosides of four stereoisomers and the 2-methoxy derivative of l-fucose ☆

M. Kiso, A. Hasegawa, H. Ishida, 1995 .

Synthesis of deoxy-L-fucose-containing sialyl Lewis X ganglioside analogues.

T. Ando, M. Kiso, A. Hasegawa, 1994, Carbohydrate research.

Synthetic studies on sialoglycoconjugates 27: Synthesis of sialyl-α(2→6)-Lewis X

M. Kiso, A. Hasegawa, H. Ishida, 1991 .

Synthetic Studies on Sialoglycoconjugates 52: Synthesis of Sialyl Lewis X Analogs Containing Azidoalkyl Groups at the Reducing End

M. Kiso, A. Hasegawa, H. Ishida, 1993 .

Synthetic Studies on Sialoglycoconjugates 50: Total Synthesis of Ganglioside GD2

M. Kiso, A. Hasegawa, H. Ishida, 1993 .

Synthetic Studies on Sialoglycoconjugates 36: α-Selective Glycoside Synthesis of N-Acetylneuraminic Acid with the Secondary Hydroxyl Group in D-Glucofyranose, 2-Acetamido-2-deoxy-D-glucopyranose and D-Galactopyranose Derivatives

M. Kiso, A. Hasegawa, M. Ogawa, 1992 .

Synthetic Studies on Sialoglycoconjugates 7: Synthesis of N-Acetylneuraminic Acid Derivatives and Analogs

M. Kiso, A. Hasegawa, M. Morita, 1989 .

Synthetic Studies on Sialoglycoconjugates 49: Novel Disaccharides and Lactams Composed of Sialic Acid and 1-Deoxynojirimycin-Potential for Biomedical Application

M. Kiso, A. Hasegawa, H. Ishida, 1993 .

Studies on 1-Deoxynojirimycin-Containing Glycans: Synthesis of Novel Disaccharides Related to Lactose, Lactosamine, and Chitobiose

M. Kiso, A. Hasegawa, H. Katagiri, 1992 .

A Convenient Synthesis of Sphingosine and Ceramide from D-Xylose or D-Galactose

M. Kiso, A. Hasegawa, J. Nakamura, 1986 .

Synthesis of sialyl Lewis X ganglioside analogues containing modified L-fucose residues.

T. Ando, M. Kiso, A. Hasegawa, 1995, Carbohydrate research.

Synthetic Studies on Sialoglycoconjugates. Part 59. Total Synthesis of Tumor‐Associated Ganglioside, Sialyl Lea.

M. Kiso, A. Hasegawa, H. Ishida, 1994 .

Synthesis of the 3'-C-carboxymethyl Lewis X derivative: A novel selectin blocker

H. Kondo, M. Kiso, A. Hasegawa, 1997 .

Synthetic Studies on Sialoglycoconjugates 85: Synthesis of Sialyl Lewis X Ganglioside Analogs Containing a Variety of Anionic Substituents in Place of Sialic Acid

M. Kiso, A. Hasegawa, H. Ishida, 1996 .

Synthetic Studies on Sialoglycoconjugates 81: Synthesis of Positional Isomers of Sialyl Lewis X Epitope Containing 1-Deoxy-d Glucose in Place of N-Acetylglucosamine, and Their Inhibitory Activity to Selectin-Mediated Adhesion

M. Kiso, A. Hasegawa, H. Ishida, 1996 .

Studies on the Thioglycosides of N-Acetylneuraminic Acid 10: Synthesis of S-(α-Sialosyl)-(2→6)-O-2-acetamido-2-deoxy-β-D-Hexopyranosyl Ceramide and Its Related Compounds

M. Kiso, A. Hasegawa, T. Terada, 1992 .

Synthesis of 1-Thio-N-acetylmuramoyl-L-alanyl-D-isoglutamine Derivatives, and Their Biological Activities. XX

M. Kiso, A. Hasegawa, I. Azuma, 1982 .

Adjuvant Activity of 6-Amino-6-Deoxy-Muramyldipeptides and Their Acylamino Derivatives on the Induction of Delayed Hypersensitivity to Azobenzenearsonate-N-Acetyl-l-Tyrosine in Guinea Pigs

I. Saiki, M. Kiso, A. Hasegawa, 1981, Infection and immunity.

Chemical modification of the carbohydrate moiety in N-acetylmuramoyl-l-alanyl-d-isoglutamine, and the immunoadjuvant activity☆

M. Kiso, A. Hasegawa, I. Azuma, 1981 .

Synthesis and immunoadjuvant activities of muramoyl-L-alanyl-D-isoglutamine and some carbohydrate analogs.

M. Kiso, A. Hasegawa, I. Azuma, 1980, Carbohydrate research.

Synthesis of N-acetyl-6-amino- and -6-(acylamino)-6-deoxymuramoyl dipeptides, and their immunoadjuvant activities.

M. Kiso, A. Hasegawa, I. Azuma, 1980, Carbohydrate research.

Synthesis of 2-deoxy-4-O-phosphono-3-O-tetradecanoyl-2-[(3R)- and (3S)-3-tetradecanoyloxytetradecanamido]-D-glucose: a diastereoisomeric pair of 4-O-phosphono-D-glucosamine derivatives (GLA-27) related to bacterial lipid A.

Y. Ogawa, M. Kiso, A. Hasegawa, 1986, Carbohydrate research.

Comparison of Murine B Cell Clonal Expansions by Synthetic Lipid A and Muramyl Dipeptide Analogs

M. Kiso, A. Hasegawa, M. Nakano, 1985, Microbiology and immunology.

Synthesis of N-[2-S -(2-Acetamido-2,3-dideoxy-D-glucopyranose-3-y1)-2-Thio-D-Lactoyl]-L-alanyl-D-isoglutamine

M. Kiso, A. Hasegawa, I. Azuma, 1984 .

Synthesis and biological activities of N-acetyl-1-thiomuramoyl-L-alanyl-D-isoglutamine and some of its lipophilic derivatives.

M. Kiso, A. Hasegawa, I. Azuma, 1983, Carbohydrate research.

Synthesis of N-[2-O-(2-acetamido-2,3-dideoxy-5-thio-d-glucopyranose-3-yl)-d-lactoyl]-l-alanyl-d-isoglutamine

M. Kiso, A. Hasegawa, I. Azuma, 1983 .

The equilibrium compositions and conformations of some carbohydrate analogs of N-acetylmuramoyl-l-alanyl-d-isoglutamine as determined by 1H-n.m.r. spectroscopy☆

M. Kiso, A. Hasegawa, I. Azuma, 1983 .

Synthesis of 2,6-di(acylamino)-2,6-dideoxy-3-O-(d-2-propanoyl-l-alanyl-d-isoglutamine)-d-glucopyranoses☆

M. Kiso, A. Hasegawa, E. Tanahashi, 1982 .

Synthesis of some carbohydrate analogs of N-acetylmuramoyl-l-alanyl-d-isoglutamine

M. Kiso, A. Hasegawa, Y. Goh, 1982 .

The chemical modification of the C-2 substituent in the sugar moiety of N-acetylmuramoyl-l-alanyl-d-isoglutamine, and the immunoadjuvant activities

M. Kiso, A. Hasegawa, Yoshimi Kaneda, 1981 .

STUDIES ON IMMUNOADJUVANT ACTIVE COMPOUNDS. PART XV. SYNTHESIS AND IMMUNOADJUVANT ACTIVITIES OF THE REPEATING, DISACCHARIDE-DIPEPTIDE UNIT OF THE BACTERIAL, CELL-WALL PEPTIDOGLYCAN AND OF SOME CARBOHYDRATE ANALOGS

M. Kiso, A. Hasegawa, I. Azuma, 1982 .

A convenient and efficient synthesis of sialyl Lewis X.

M. Kiso, A. Hasegawa, H. Ishida, 1998, Bioscience, biotechnology, and biochemistry.

Application of liposomes for cancer metastasis

H. Tsukada, I. Saiki, J. Murata, 1997 .

Inhibitory Effect of Recombinant Fibronectin Polypeptides on the Adhesion of Liver‐metastatic Lymphoma Cells to Hepatic Sinusoidal Endothelial Cells and Tumor Invasion

I. Saiki, M. Kiso, A. Hasegawa, 1994, Japanese journal of cancer research : Gann.

High affinity binding of the leucocyte adhesion molecule L-selectin to 3'-sulphated-Le(a) and -Le(x) oligosaccharides and the predominance of sulphate in this interaction demonstrated by binding studies with a series of lipid-linked oligosaccharides.

T. Watanabe, M. Kiso, A. Hasegawa, 1992, Biochemical and biophysical research communications.

Simple and efficient strategy for making β-(1→6)-linked galactooligosaccharides using ‘naked’ galactopyranosides as acceptors

M. Kiso, A. Hasegawa, H. Jennings, 1995 .

Studies on cyclitols—XIII

A. Hasegawa, H. Z. Sable, 1969 .

ON THE SPECIFICITY OF ANTI-SULFOGLUCURONOSYL GLYCOLIPID ANTIBODIES

M. Kiso, A. Hasegawa, R. Yu, 1998 .

Studies on Cyclic Polyols. VII. The Synthesis of Some Cyclopentaneaminocyclitols1

A. Hasegawa, H. Z. Sable, 1966 .

Synthetic studies on selectin ligands/inhibitors. Synthesis and biological evaluation of sulfated and phosphorylated beta-D-galacto- and lactopyranosides containing fatty-alkyl residues of different carbon chain lengths.

T. Jomori, M. Kiso, A. Hasegawa, 1998, Chemical and pharmaceutical bulletin.

Total synthesis of kanamycin-A.

A. Hasegawa, N. Kurihara, M. Nakajima, 1968, Tetrahedron Letters.

Studies on cyclic polyols. XI. New syntheses of inosadiamines.

A. Hasegawa, H. Z. Sable, 1968, Journal of Organic Chemistry.

Studies on Cyclic Polyols. VIII. Neighboring-Group Effects in Epoxide Opening and in Addition of Hypobromous Acid1

A. Hasegawa, H. Z. Sable, 1966 .

Studies on Cyclic Polyols. VI. Synthesis of Anhydrocyclopentanetetrols and Aminocyclopentanetriols1

A. Hasegawa, H. Z. Sable, 1966 .

Conjugates of biologically active lipid a-subunit analogs with 3-deoxy-d-manno-2-octulosonic acid (KDO) and its methyl ester

Y. Ogawa, M. Kiso, A. Hasegawa, 1988 .

Synthesis of 2-deoxystreptamine

A. Hasegawa, N. Kurihara, M. Nakajima, 1964 .

Synthesis and immunoadjuvant activity of acylamino analogs of N-acetylmuramoyl-L-alanyl-D-isoglutamine.

M. Kiso, A. Hasegawa, I. Azuma, 1982 .

Solvent Effect and Anchimeric Assistance on α-Glycosylation

A. Hasegawa, M. Nakajima, D. Nishimura, 1972 .

Synthetic Studies on Carbohydrate Antibiotics: Part VIII1) Synthesis of Kanosaminide and Related α-Aminoglucosides

A. Hasegawa, N. Kurihara, M. Nakajima, 1968 .

Synthetic Studies on Carbohydrate Antibiotics: Part IX. Synthesis of Kanamycin A and Related Compounds

A. Hasegawa, N. Kurihara, M. Nakajima, 1968 .

Synthetic studies on amino-α-glycosides of aminocyclitols. Synthesis of kanamycin analogues

A. Hasegawa, M. Nakajima, D. Nishimura, 1973 .

Immunopharmacological activities of 2-keto-3-deoxyoctonic acid-(alpha 2----6)-linked 4-O-phosphono-D-glucosamine derivatives carrying N- and 3-O-acyl substituents

M. Kiso, A. Hasegawa, Y. Kumazawa, 1989, Infection and immunity.

6-O-glycosylation of a lipid A-subunit analog (GLA-27) with methyl (4,5,7,8-tetra-O-acetyl-3-deoxy-α-d-manno-2-octulopyranosyl bromide)onate (a KDO derivative)

M. Kiso, A. Hasegawa, F. Unger, 1987 .

Synthesis of nonreducing-sugar subunit analogs of bacterial lipid a carrying an amide-group (3R)-3-acyloxytetradecanoyl group

Shinji Tanaka, Y. Ogawa, M. Kiso, 1987 .

Synthesis of 1,5-Anhydro- 2-deoxy- 4-O-phosphono-3-O-tetradecanoyl-2-[(3R)- and (3S)-3-Tetradecanoyloxytetradecanamido]-D-glucitol (GLA-40) Related to Bacterial Lipid A

Shinji Tanaka, Y. Ogawa, M. Kiso, 1986 .

Effects of backbone structures and stereospecificities of lipid A-subunit analogues on their biological activities.

M. Kiso, A. Hasegawa, Y. Kumazawa, 1986, Journal of biochemistry.

Structural requirements for inducing in vitro B lymphocyte activation by chemically synthesized derivatives related to the nonreducing D‐glucosamine subunit of lipid A

M. Kiso, A. Hasegawa, Y. Kumazawa, 1986, European journal of immunology.

Biological activities of chemically synthesized partial structure analogues of lipid A.

M. Kiso, A. Hasegawa, M. Matsuura, 1985, Journal of biochemistry.

B cell activation and adjuvant activities of chemically synthesized analogues of the nonreducing sugar moiety of lipid A

M. Kiso, A. Hasegawa, Y. Kumazawa, 1985, European journal of immunology.

Synthesis of Biologically Active, Novel Monosaccharide Analogs of Lipid A

M. Kiso, A. Hasegawa, H. Ishida, 1984 .

Antiherpes activity of chemically synthesized lipid A-subunit analogue GLA-60 in immunosuppressed mice.

S. Ikeda, M. Kiso, A. Hasegawa, 1989, Antiviral research.

Antiviral and immunomodulating activities of chemically synthesized lipid A-subunit analogues GLA-27 and GLA-60.

S. Ikeda, M. Kiso, A. Hasegawa, 1988, Antiviral research.

Synthesis and properties of 5'-triphosphoryl 2'-5' oligoadenylates (2-5A), and a general method for synthesis of 3', 5'-bisphosphorylated oligonucleotides.

E. Ohtsuka, M. Ikehara, A. Hasegawa, 1981, Nucleic acids research.

Protective activity of the lipid A analogue GLA-60 against murine cytomegalovirus infection in immunodeficient mice.

E. De Clercq, S. Ikeda, J. Neyts, 1993, The Journal of general virology.

New synthetic immunomodulators combining a 4-O-phosphono-D-glucosamine derivative related to bacterial lipid A with 1-deoxy-N-acetylmuramoyl dipeptide analogs.

Y. Ogawa, M. Kiso, A. Hasegawa, 1987, Carbohydrate research.

Synthesis of N-Trifluoroacetyl-L-acosamine, N-Trifluoroacetyl-L-daunosamine and Their 1-Thio Analogs.

R. Whistler, A. Hasegawa, I. Pelyvás, 1986 .

Modification of immunopharmacological activities of synthetic monosaccharide lipid A analogue, GLA60, by lysozyme.

M. Kiso, A. Hasegawa, Y. Adachi, 1992, Journal of biochemistry.

DT‐5461, a New Synthetic Lipid A Analogue, Inhibits Lung and Liver Metastasis of Tumor in Mice

Katsuaki Sato, Y. Yoo, I. Saiki, 1992, Japanese journal of cancer research : Gann.

Activation by synthetic lipid A subunit analogues (GLA compounds) of tumoricidal properties in human blood monocytes.

I. Saiki, H. Maeda, M. Kiso, 1990, Vaccine.

Production of interleukin 1 from human monocytes stimulated by synthetic lipid A subunit analogues.

I. Saiki, H. Maeda, J. Murata, 1990, International journal of immunopharmacology.

Synthesis and biological activity of some lipophilic derivatives of 1-thio-muramoyl-L-alanyl-D-isoglutamine.

E. Seki, M. Kiso, A. Hasegawa, 1984, Carbohydrate research.

Synthesis and immunoadjuvant activities of novel N-acylmuramoyl dipeptides related to the lipid A constituent of the bacterial lipopolysaccharide

M. Kiso, A. Hasegawa, I. Azuma, 1981 .

Structural features that influence the ability of lipid A and its analogs to abolish expression of suppressor T cell activity

A. Hasegawa, S. Kusumoto, N. Qureshi, 1992, Infection and immunity.

Immunosuppression induced by non-reducing acylated monosaccharide subunits of lipid A.

M. Kiso, A. Hasegawa, M. Mohrman, 1992, International journal of immunopharmacology.

Expression of endotoxic activities by synthetic monosaccharide lipid A analogs with alkyl-branched acyl substituents

M. Kiso, A. Hasegawa, M. Matsuura, 1995, Infection and immunity.

Enhancement of nonspecific resistance to viral infection by chemically synthesized lipid A-subunit analogs with different backbone structures and acyl groups.

S. Ikeda, M. Kiso, A. Hasegawa, 1988, Antiviral research.

Requirement of a properly acylated beta(1-6)-D-glucosamine disaccharide bisphosphate structure for efficient manifestation of full endotoxic and associated bioactivities of lipid A

T. Ogawa, M. Kiso, A. Hasegawa, 1987, Infection and immunity.

Analysis of antigenic reactivity of synthetic monosaccharide lipid A analogues with monoclonal antibodies

M. Kiso, A. Hasegawa, S. Arata, 1987 .

Biological activities of fundamental, carbohydrate skeleton of lipid A containing amide-linked 3-hydroxytetradecanoic acid.

M. Kiso, A. Hasegawa, I. Azuma, 1981 .

Effect of acyl substituents of synthetic lipid A-subunit analogues on their immunomodulating antiviral activity.

S. Ikeda, M. Kiso, A. Hasegawa, 1990, Antiviral research.

Adjuvant activity of carbohydrate analogs of N-acetylmuramyl-L-alanyl-D-isoglutamine on the induction of delayed-type hypersensitivity to azobenzenearsonate-N-acetyl-L-tyrosine in guinea pigs

I. Saiki, M. Kiso, A. Hasegawa, 1981, Infection and immunity.

Inhibition of tumor‐induced angiogenesis by the administration of recombinant interferon‐γ followed by a synthetic lipid‐a subunit analogue (GLA‐60)

Katsuaki Sato, Y. Yoo, I. Saiki, 1992, International journal of cancer.

Antitumor and antimicrobial activities of lipid A-subunit analogue GLA-27.

S. Ikeda, M. Kiso, A. Hasegawa, 1988, Journal of clinical & laboratory immunology.

Enhancement of nonspecific resistance to bacterial infections and tumor regressions by treatment with synthetic lipid A-subunit analogs. Critical role of N- and 3-O-linked acyl groups in 4-O-phosphono-D-glucosamine derivatives.

M. Kiso, A. Hasegawa, Y. Kumazawa, 1989, International journal of immunopharmacology.

Inhibition in mice of experimental metastasis of B16 melanoma by the synthetic lipid A-subunit analogue GLA-60.

M. Kiso, A. Hasegawa, Y. Kumazawa, 1991, International journal of immunopharmacology.

Enhancement of nonspecific resistance to microbial infections of synthetic lipid A-subunit analogues of GLA-27 modified at the C1 position of the glucosamine backbone.

S. Ikeda, M. Kiso, A. Hasegawa, 1990, International journal of immunopharmacology.

Novel Disaccharides Containing 3-Deoxy-D-Manno-2-Octulosonic Acid (KDO) and Lipid a Subunit Analogs

M. Kiso, A. Hasegawa, F. Unger, 1987 .

Gangliosides inhibit the release of interleukin-1β in amyloid β-protein-treated human monocytic cells

T. Miyatake, M. Kiso, A. Hasegawa, 2001, Journal of Molecular Neuroscience.

Sulfated glycolipids are ligands for a lymphocyte homing receptor, L-selectin (LECAM-1), Binding epitope in sulfated sugar chain.

T. Watanabe, M. Kiso, A. Hasegawa, 1993, Biochemical and biophysical research communications.

Studies on the specificity and sensitivity of the influenza C virus binding assay for 9-O-acetylated sialic acids and its application to human melanomas.

M. Kiso, A. Hasegawa, H. Ishida, 2000, Journal of biochemistry.

Sialyl Lewisx Antigen as Defined by Monoclonal Antibody AM-3 Is a Marker of Dysplasia in the Colonic Adenoma-Carcinoma Sequence

C. Hanski, F. Hanisch, A. Hasegawa, 1992 .

Anti-inflammatory effects of sulfatides in selectin-dependent acute lung injury.

P. Ward, M. Kiso, A. Hasegawa, 1995, International immunology.

Synthesis and Biological Activities of Bacterial Cell-wall and Cell-surface Complex Carbohydrates

M. Kiso, A. Hasegawa, 1984 .

Synthetic Studies on Selectin Ligands/Inhibitors: Synthesis and Inhibitory Activity of 2-O-Fucosyl Sulfatides Containing 2-Branched Fatty Alkyl Residues in Place of Ceramide

T. Jomori, M. Kiso, A. Hasegawa, 1998 .

Synthetic Studies on Selectin Ligands/Inhibitors: One-Pot Synthesis of the Mono- and Oligo-Sulfated 2-(Tetradecyl)Hexadecyl β-D-Galacto- and Lactopyranosides as the Sulfatide Mimetics 1

M. Kiso, A. Hasegawa, H. Ishida, 1997 .

Synthetic Studies on Sialoglycoconjugates 71: Synthesis of Sulfo- and Sialyl-Lewis × Epitope Analogs Containing the 1-Deoxy-N-acetylgulcosamine in Place of N-Acetylglucosamine Residue

M. Kiso, A. Hasegawa, H. Ishida, 1995 .

The Chemical Modification of the C-1 Substituent of A 4-O-Phosphono-O-Glucosamine Derivative (GLA-27) Related to Bacterial Lipid A

Y. Ogawa, M. Kiso, A. Hasegawa, 1987 .

Structural Basis for the Resistance of Tay-Sachs Ganglioside GM2 to Enzymatic Degradation*

A. Bernardi, M. Kiso, A. Hasegawa, 1999, The Journal of Biological Chemistry.

Purification and characterization of sialidase L, a NeuAc alpha 2-->3Gal-specific sialidase.

M. Chou, M. Kiso, A. Hasegawa, 1994, The Journal of biological chemistry.

Drift of the sialyl-linkage specific recognition of the sialidase of influenza B virus isolates.

E. Deya, M. Kiso, A. Hasegawa, 1993, Journal of biochemistry.

Purification and characterization of a membrane-associated ganglioside sialidase from bovine brain.

T. Wada, M. Kiso, A. Hasegawa, 1998, Journal of biochemistry.

Synthesis of Sialoglycoconjugates

A. Hasegawa, 1997, Modern Methods in Carbohydrate Synthesis.

Studies on tRNA and Related Compounds. XXXVII. Synthesis and Physical Properties of 2'- or 3'-O-(o-Nitrobenzyl) nucleosides : the Use of o-Nitrophenyldiazomethane as a Synthetic Reagent

E. Ohtsuka, M. Ikehara, A. Hasegawa, 1981 .

Lipopolysaccharide Agonists or Antagonists of Bacterial Analogues in Human Monocytic Cells as Activity of Monosaccharide Lipid A

M. Kiso, A. Hasegawa, M. Matsuura, 1999 .

Isolation and structural characterization of fucosylated gangliosides with linear poly-N-acetyllactosaminyl chains from human granulocytes.

J. Lehmann, J. Peter-Katalinic, C. Hanski, 1996, Glycobiology.

Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endothelium.

R. Kannagi, M. Kiso, A. Hasegawa, 1993, Cancer research.

Structural determination of gangliosides that bind to influenza A, B, and C viruses by an improved binding assay: strain-specific receptor epitopes in sialo-sugar chains.

T. Ito, E. Deya, M. Kiso, 1992, Virology.

A convenient synthesis of 2-deoxy-2-(d- and -(l-3-hydroxytetradecanoyl-amino)-d-glucose: diastereoisomers of the monomeric, lipid A component of the bacterial Iipopolysaccharide

M. Kiso, A. Hasegawa, Satoshi Murase, 1981 .

Synthesis of 4-acetamido-N-acetyl-4-deoxy- and 4,6-di(acetamido)-N-acetyl-4,6-dideoxy-muramoyl-l-alanyl-d-isoglutamine derivatives

M. Kiso, A. Hasegawa, E. Tanahashi, 1982 .

Studies on immunoadjuvant active compounds. VI. Syntheses and immunoadjuvant activity of some carbohydrate analogs of N-acetylmuramyl-L-alanyl-D-isoglutamine.

M. Kiso, A. Hasegawa, I. Azuma, 1980 .