Xianzhong Meng

发表

Preconditioning up-regulates the soluble TNF receptor I response to endotoxin.

Ben M. Tsai, D. Meldrum, Mei-Jan Wang, 2004, The Journal of surgical research.

Early kidney TNF-α expression mediates neutrophil infiltration and injury after renal ischemia-reperfusion.

A. Harken, D. Meldrum, A. Ayala, 1999, American journal of physiology. Regulatory, integrative and comparative physiology.

TNF-α and myocardial depression in endotoxemic rats: temporal discordance of an obligatory relationship.

A. Harken, D. Meldrum, Xianzhong Meng, 1998, American journal of physiology. Regulatory, integrative and comparative physiology.

Hemoglobin-based oxygen carrier induces heme oxygenase-1 in the heart and lung but not brain.

E. Moore, Xianzhong Meng, A. Banerjee, 2009, Journal of the American College of Surgeons.

Simvastatin down-regulates osteogenic response in cultured human aortic valve interstitial cells.

M. Weyant, Xianzhong Meng, D. Fullerton, 2019, The Journal of thoracic and cardiovascular surgery.

Abstract 165: Microrna-486 Regulates Fibroblast-to-myofibroblast Transition in Human Aortic Valve Interstitial Cells

Xianzhong Meng, L. Ao, D. Fullerton, 2015, Arteriosclerosis, Thrombosis, and Vascular Biology.

The intestinal microbiota associated with cardiac valve calcification differs from that of coronary artery disease.

Xianzhong Meng, L. Ao, Hai-yue Liu, 2019, Atherosclerosis.

Pretreatment With Diazoxide Attenuates Spinal Cord Ischemia-Reperfusion Injury Through Signaling Transducer and Activator of Transcription 3 Pathway.

J. Cleveland, T. Ryan, M. Weyant, 2019, The Annals of thoracic surgery.

TLR4 Stimulation Promotes Human AVIC Fibrogenic Activity through Upregulation of Neurotrophin 3 Production

Xianzhong Meng, L. Ao, D. Fullerton, 2020, International journal of molecular sciences.

Pro-osteogenic phenotype of human aortic valve interstitial cells is associated with higher levels of Toll-like receptors 2 and 4 and enhanced expression of bone morphogenetic protein 2.

J. Cleveland, Xiaoping Yang, Xianzhong Meng, 2009, Journal of the American College of Cardiology.

Gender-Specific Transfusion Affects Tumor-Associated Neutrophil: Macrophage Ratios in Murine Pancreatic Adenocarcinoma

C. Silliman, Xianzhong Meng, D. Fullerton, 2010, Journal of Gastrointestinal Surgery.

Interleukin-1 Beta induces an inflammatory phenotype in human aortic valve interstitial cells through nuclear factor kappa Beta.

J. Cleveland, M. Weyant, Xianzhong Meng, 2013, The Annals of thoracic surgery.

Optimizing Nicorandil for Spinal Cord Protection in a Murine Model of Complex Aortic Intervention.

J. Cleveland, M. Weyant, Xianzhong Meng, 2021, Seminars in thoracic and cardiovascular surgery.

The Evolution of Chemokine Release Supports a Bimodal Mechanism of Spinal Cord Ischemia and Reperfusion Injury

J. Cleveland, M. Weyant, Xianzhong Meng, 2012, Circulation.

Dysfunctional Mechanisms of Anti-inflammation in Aortic Stenosis

Xianzhong Meng, D. Fullerton, 2013 .

Ablation of toll-like receptor 4 attenuates aging-induced myocardial remodeling and contractile dysfunction through NCoRI-HDAC1-mediated regulation of autophagy.

Jun Ren, Yingmei Zhang, Xianzhong Meng, 2018, Journal of molecular and cellular cardiology.

Klotho suppresses high phosphate-induced osteogenic responses in human aortic valve interstitial cells through inhibition of Sox9

J. Cleveland, Xianzhong Meng, L. Ao, 2017, Journal of Molecular Medicine.

Ischemic dose-response in the spinal cord: both immediate and delayed paraplegia.

J. Cleveland, M. Watkins, M. Weyant, 2012, The Journal of surgical research.

Erythropoietin activates the phosporylated cAMP [adenosine 3'5' cyclic monophosphate] response element-binding protein pathway and attenuates delayed paraplegia after ischemia-reperfusion injury.

J. Cleveland, M. Weyant, Xianzhong Meng, 2015, Journal of Thoracic and Cardiovascular Surgery.

Alpha-2 agonist attenuates ischemic injury in spinal cord neurons.

J. Cleveland, M. Weyant, Xianzhong Meng, 2015, The Journal of surgical research.

Preservation of motor function after spinal cord ischemia and reperfusion injury through microglial inhibition.

J. Cleveland, M. Weyant, Xianzhong Meng, 2013, The Annals of thoracic surgery.

Liposomal Delivery of Purified Inhibitory-κBα Inhibits Tumor Necrosis Factor-α–Induced Human Vascular Smooth Muscle Proliferation

A. Harken, C. Dinarello, Xianzhong Meng, 1999 .

Biglycan Induces the Expression of Osteogenic Factors in Human Aortic Valve Interstitial Cells via Toll-Like Receptor-2

J. Cleveland, Xianzhong Meng, L. Ao, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Toll-like Receptor 4 Mediates the Inflammatory Responses and Matrix Protein Remodeling in Remote Non-Ischemic Myocardium in a Mouse Model of Myocardial Ischemia and Reperfusion

J. Cleveland, Xianzhong Meng, L. Ao, 2015, PloS one.

Elevated Expression of TLR2 in Aging Hearts Exacerbates Cardiac Inflammatory Response and Adverse Remodeling Following Ischemia and Reperfusion Injury

Xianzhong Meng, L. Ao, D. Fullerton, 2022, Frontiers in Immunology.

Statins Inhibit Toll-Like Receptor 4-Mediated Growth of Human Esophageal Adenocarcinoma Cells.

M. Weyant, Xianzhong Meng, Allana M. White, 2020, The Journal of surgical research.

Radiation induces osteogenesis in human aortic valve interstitial cells.

J. Cleveland, M. Weyant, Xianzhong Meng, 2012, The Journal of thoracic and cardiovascular surgery.

[A low level of TNF-mediates hemorrhage-induced acute lung injury via p55 TNF receptor].

A. Harken, Xianzhong Meng, C. Raeburn, 2001, Zhonghua yi xue za zhi.

Klotho suppresses the inflammatory responses and ameliorates cardiac dysfunction in aging endotoxemic mice

J. Cleveland, Xianzhong Meng, L. Ao, 2017, Oncotarget.

Over-expression of neurotrophin 3 in human aortic valves affected by calcific disease induces the osteogenic responses via the Trk-Akt pathway.

J. Cleveland, Xianzhong Meng, L. Ao, 2015, Biochimica et biophysica acta.

LysoPCs induce Hck‐ and PKCδ‐mediated activation of PKCγ causing p47phox phosphorylation and membrane translocation in neutrophils

C. Silliman, D. Elzi, Xianzhong Meng, 2017, Journal of leukocyte biology.

Activation of sirtuin 1/3 improves vascular hyporeactivity in severe hemorrhagic shock by alleviation of mitochondrial damage

Xianzhong Meng, N. Burns, R. Song, 2015, Oncotarget.

Human Myocardial Tissue TNFαExpression Following Acute Global IschemiaIn Vivo

A. Harken, D. Meldrum, C. Dinarello, 1998 .

Gender disparity in the role of TLR2 in post-ischemic myocardial inflammation and injury.

J. Cleveland, Xianzhong Meng, L. Ao, 2015, International journal of clinical and experimental medicine.

Myocardial TLR4 is a determinant of neutrophil infiltration after global myocardial ischemia: mediating KC and MCP-1 expression induced by extracellular HSC70.

J. Cleveland, Xianzhong Meng, L. Ao, 2009, American journal of physiology. Heart and circulatory physiology.

Cross-Talk Between the Toll-Like Receptor 4 and Notch1 Pathways Augments the Inflammatory Response in the Interstitial Cells of Stenotic Human Aortic Valves

J. Cleveland, Xianzhong Meng, L. Ao, 2012, Circulation.

Signaling for myocardial depression in hemorrhagic shock: roles of Toll-like receptor 4 and p55 TNF-α receptor

A. Harken, Xianzhong Meng, L. Ao, 2005 .

Optimized induction of beta common receptor enhances the neuroprotective function of erythropoietin in spinal cord ischemic injury

J. Cleveland, T. Ryan, M. Weyant, 2018, The Journal of thoracic and cardiovascular surgery.

Ischemia Alone is Sufficient to Induce TNF-&agr; mRNA and Peptide in the Myocardium

C. Cairns, A. Harken, Xianzhong Meng, 2002, Shock.

LPS induces late cardiac functional protection against ischemia independent of cardiac and circulating TNF-α.

A. Harken, D. Meldrum, Xianzhong Meng, 1997, American journal of physiology. Heart and circulatory physiology.

ICAM-1 and VCAM-1 mediate endotoxemic myocardial dysfunction independent of neutrophil accumulation.

A. Harken, Xianzhong Meng, L. Ao, 2002, American journal of physiology. Regulatory, integrative and comparative physiology.

The interaction between myocardial depressant factors in endotoxemic cardiac dysfunction: role of TNF-alpha in TLR4-mediated ICAM-1 expression.

C. Dinarello, Xianzhong Meng, L. Ao, 2007, Cytokine.

Toll-like receptor-4 signaling mediates pulmonary neutrophil sequestration in response to gram-positive bacterial enterotoxin.

R. McIntyre, Xianzhong Meng, D. Bensard, 2002, The Journal of surgical research.

Simvastatin reduces the TLR4-induced inflammatory response in human aortic valve interstitial cells.

M. Weyant, Xianzhong Meng, D. Fullerton, 2018, The Journal of surgical research.

Matrix Gla protein regulates calcification of the aortic valve.

M. Weyant, Xianzhong Meng, D. Fullerton, 2015, The Journal of surgical research.

The Presence of the M-type Secretory Phospholipase A2 Receptor on Neutrophils and Its Role in Elastase Release and Adhesion

C. Silliman, G. Zallen, D. Elzi, 2002 .

Presence of the M-type sPLA(2) receptor on neutrophils and its role in elastase release and adhesion.

E. Moore, C. Silliman, G. Zallen, 2002, American journal of physiology. Cell physiology.

Myocardial gene reprogramming associated with a cardiac cross-resistant state induced by LPS preconditioning.

A. Harken, S. Nordeen, Xianzhong Meng, 1998, American journal of physiology. Cell physiology.

Increased levels of myocardial IκB-α protein promote tolerance to endotoxin.

A. Harken, D. Meldrum, Xianzhong Meng, 1998, American journal of physiology. Heart and circulatory physiology.

Augmented Osteogenic Responses in Human Aortic Valve Cells Exposed to oxLDL and TLR4 Agonist: A Mechanistic Role of Notch1 and NF-κB Interaction

Xianzhong Meng, L. Ao, D. Fullerton, 2014, PloS one.

Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosis.

J. Cleveland, M. Weyant, Xiaoping Yang, 2008, American journal of physiology. Cell physiology.

Plasma from stored packed red blood cells and MHC class I antibodies causes acute lung injury in a 2-event in vivo rat model.

E. Moore, C. Silliman, Xianzhong Meng, 2009, Blood.

Liposomal Delivery of Heat Shock Protein 72 Into Renal Tubular Cells Blocks Nuclear Factor-&kgr;B Activation, Tumor Necrosis Factor-&agr; Production, and Subsequent Ischemia-Induced Apoptosis

A. Burnett, K. Meldrum, D. Meldrum, 2003, Circulation research.

TLR4 mediates LPS-induced HO-1 expression in mouse liver: Role of TNF-α and IL-1β

A. Harken, Xianzhong Meng, L. Ao, 2003 .

Hemoglobin-based oxygen carrier induces hepatic heme oxygenase 1 expression in Kupffer cells.

M. Weyant, E. Moore, Xianzhong Meng, 2007, Surgery.

The 5-Lipoxygenase Pathway Is Required for Acute Lung Injury Following Hemorrhagic Shock

E. Moore, R. Murphy, S. Zarini, 2012, Shock.

Enhanced monocyte chemoattractant protein-1 production in aging mice exaggerates cardiac depression during endotoxemia

Xianzhong Meng, L. Ao, D. Fullerton, 2014, Critical Care.

MicroRNA-204 Deficiency in Human Aortic Valves Elevates Valvular Osteogenic Activity

Xianzhong Meng, L. Ao, D. Fullerton, 2019, International journal of molecular sciences.

Notch1 Promotes the Pro-Osteogenic Response of Human Aortic Valve Interstitial Cells via Modulation of ERK1/2 and Nuclear Factor-&kgr;B Activation

M. Weyant, Xianzhong Meng, L. Ao, 2013, Arteriosclerosis, thrombosis, and vascular biology.

MMP-12-Induced Pro-osteogenic Responses in Human Aortic Valve Interstitial Cells.

Xianzhong Meng, J. Jaggers, D. Fullerton, 2019, The Journal of surgical research.

Oxidized Low Density Lipoprotein Induces Bone Morphogenetic Protein-2 in Coronary Artery Endothelial Cells via Toll-like Receptors 2 and 4*

Xianzhong Meng, L. Ao, D. Fullerton, 2011, The Journal of Biological Chemistry.

Synergetic Induction of NGF With Diazoxide and Erythropoietin Attenuates Spinal Cord Ischemic Injury.

T. Ryan, M. Weyant, Xianzhong Meng, 2019, The Journal of surgical research.

Adult aortic valve interstitial cells have greater responses to toll-like receptor 4 stimulation.

Xianzhong Meng, J. Jaggers, D. Fullerton, 2015, The Annals of thoracic surgery.

TNF-α-dependent bilateral renal injury is induced by unilateral renal ischemia-reperfusion

A. Harken, K. Meldrum, D. Meldrum, 2002 .

Mycobacterium tuberculosis Induces Interleukin-32 Production through a Caspase- 1/IL-18/Interferon-γ-Dependent Mechanism

L. Joosten, M. Netea, E. Chan, 2006, PLoS medicine.

Extracellular heat shock cognate protein 70 induces cardiac functional tolerance to endotoxin: differential effect on TNF-alpha and ICAM-1 levels in heart tissue.

Xianzhong Meng, L. Ao, D. Fullerton, 2010, Cytokine.

Attenuated Recovery of Contractile Function in Aging Hearts Following Global Ischemia/Reperfusion: Role of Extracellular HSP27 and TLR4

J. Cleveland, Xianzhong Meng, L. Ao, 2016, Molecular Medicine.

Microfilaments facilitate TLR4-mediated ICAM-1 expression in human aortic valve interstitial cells.

J. Cleveland, Xiaoping Yang, Xianzhong Meng, 2011, The Journal of surgical research.

Heat shock protein 27: induction by gastroduodenal reflux in vivo and augmentation of human esophageal mucosal cell growth in vitro.

M. Weyant, Xianzhong Meng, A. Babu, 2010, The Journal of thoracic and cardiovascular surgery.

Toll-Like Receptor-4 Is a Mediator of Proliferation in Esophageal Adenocarcinoma.

M. Weyant, Xianzhong Meng, L. Ao, 2019, The Annals of thoracic surgery.

rapid communication Early kidney TNF- a expression mediates neutrophil inﬁltration and injury after renal ischemia-reperfusion

A. Harken, D. Meldrum, A. Ayala, 1999 .

Toll-Like Receptor 4–Dependent Microglial Activation Mediates Spinal Cord Ischemia–Reperfusion Injury

J. Cleveland, M. Weyant, Xianzhong Meng, 2013, Circulation.

The Secretory Phospholipase A2 Gene is Required for Gastroesophageal Reflux-Related Changes in Murine Esophagus

M. Weyant, Xianzhong Meng, A. Banerjee, 2009, Journal of Gastrointestinal Surgery.

Cytokines link Toll-like receptor 4 signaling to cardiac dysfunction after global myocardial ischemia.

C. Dinarello, Xianzhong Meng, L. Ao, 2008, The Annals of thoracic surgery.

Monocytes augment inflammatory responses in human aortic valve interstitial cells via β2-integrin/ICAM-1-mediated signaling

Xianzhong Meng, L. Ao, D. Fullerton, 2022, Inflammation Research.

Adrenergic induction of bimodal myocardial protection: signal transduction and cardiac gene reprogramming.

A. Harken, D. Meldrum, Xianzhong Meng, 1999, American journal of physiology. Regulatory, integrative and comparative physiology.

Trimethylamine -N-oxide induces osteogenic responses in human aortic valve interstitial cells in vitro and aggravates aortic valve lesions in mice.

Xianzhong Meng, L. Ao, H. Ren, 2021, Cardiovascular research.

Synergistic Reduction of Apoptosis With Diazoxide and Erythropoietin in Spinal Cord Ischemic Injury.

J. Cleveland, T. Ryan, M. Weyant, 2018, The Annals of thoracic surgery.

OxLDL Induces PiT-1 Expression in Human Aortic Valve Interstitial Cells

M. Weyant, Xianzhong Meng, D. Fullerton, 2014 .

ox-LDL induces PiT-1 expression in human aortic valve interstitial cells.

M. Weyant, Xianzhong Meng, D. Fullerton, 2013, Journal of Surgical Research.

Ghrelin reduces myocardial injury following global ischemia and reperfusion via suppression of myocardial inflammatory response

J. Cleveland, Xianzhong Meng, L. Ao, 2013 .

Simvastatin Inhibits Histologic Changes Associated with Gastroduodenal Reflux in a Murine Model

M. Weyant, Xianzhong Meng, D. Fullerton, 2022, Digestive Diseases and Sciences.

Glutamine attenuates endotoxin-induced lung metabolic dysfunction: potential role of enhanced heat shock protein 70.

N. Serkova, P. Wischmeyer, Xianzhong Meng, 2005, Nutrition.

Toll-like receptor 4 mediates oxidized LDL-induced macrophage differentiation to foam cells.

J. Cleveland, Xianzhong Meng, D. Fullerton, 2011, The Journal of surgical research.

Secretory phospholipase A2 is required to produce histologic changes associated with gastroduodenal reflux in a murine model.

J. Cleveland, M. Weyant, Xianzhong Meng, 2008, The Journal of thoracic and cardiovascular surgery.

Basic nutritional investigation Glutamine attenuates endotoxin-induced lung metabolic dysfunction: potential role of enhanced heat shock protein 70

N. Serkova, P. Wischmeyer, Xianzhong Meng, 2005 .

TNF-alpha-dependent bilateral renal injury is induced by unilateral renal ischemia-reperfusion.

A. Harken, K. Meldrum, D. Meldrum, 2002, American journal of physiology. Heart and circulatory physiology.

Myocardial TLR 4 is a determinant of neutrophil infiltration after global myocardial ischemia : mediating KC and MCP-1 expression induced by extracellular HSC 70

J. Cleveland, Xianzhong Meng, L. Ao, 2009 .

ytokines Link Toll-Like Receptor 4 Signaling to ardiac Dysfunction After Global Myocardial

Xianzhong Meng, L. Ao, A. Banerjee, 2008 .

Secretory Phospholipase A2 Inhibition Attenuates Adhesive Properties of Esophageal Barrett's Cells.

M. Weyant, Xianzhong Meng, Allana M. White, 2020, The Journal of surgical research.

Attenuation of spinal cord ischemia-reperfusion injury by specific α-2a receptor activation with dexmedetomidine.

M. Weyant, Xianzhong Meng, D. Fullerton, 2012, Journal of vascular surgery.

Human Myocardium Releases Heat Shock Protein 27 (HSP27) after Global Ischemia: The Proinflammatory Effect of Extracellular HSP27 through Toll-like Receptor (TLR)-2 and TLR4

J. Cleveland, Xianzhong Meng, L. Ao, 2014, Molecular medicine.

NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium.

D. Srivastava, Kathryn N. Ivey, Xianzhong Meng, 2015, Journal of molecular and cellular cardiology.

Single-cell RNA-seq reveals a critical role of novel pro-inflammatory EndMT in mediating adverse remodeling in coronary artery–on–a–chip

C. Dinarello, Xianzhong Meng, L. Ao, 2021, Science Advances.

Toll-like Receptor 4 Mediates Reflux-Induced Inflammation in a Murine Reflux Model.

M. Weyant, Xianzhong Meng, D. Fullerton, 2021, Seminars in thoracic and cardiovascular surgery.

An epigenetic regulatory loop controls pro-osteogenic activation by TGF-β1 or bone morphogenetic protein 2 in human aortic valve interstitial cells

Xianzhong Meng, L. Ao, D. Fullerton, 2017, The Journal of Biological Chemistry.

Double-stranded RNA upregulates the expression of inflammatory mediators in human aortic valve cells through the TLR3-TRIF-noncanonical NF-κB pathway.

Xianzhong Meng, L. Ao, D. Fullerton, 2017, American journal of physiology. Cell physiology.

BMP-2 and TGF-β1 mediate biglycan-induced pro-osteogenic reprogramming in aortic valve interstitial cells

Xianzhong Meng, L. Ao, D. Fullerton, 2015, Journal of Molecular Medicine.

Soluble biglycan induces the production of ICAM-1 and MCP-1 in human aortic valve interstitial cells through TLR2/4 and the ERK1/2 pathway

Xianzhong Meng, L. Ao, D. Fullerton, 2014, Inflammation Research.

Modulation of growth in human esophageal adenocarcinoma cells by group IIa secretory phospholipase A(2).

M. Weyant, Xianzhong Meng, D. Fullerton, 2010, The Journal of thoracic and cardiovascular surgery.

Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3

C. Dinarello, Xianzhong Meng, L. Ao, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Altered MicroRNA Expression Is Responsible for the Pro‐Osteogenic Phenotype of Interstitial Cells in Calcified Human Aortic Valves

J. Cleveland, Xianzhong Meng, L. Ao, 2017, Journal of the American Heart Association.

Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: role of Smad1 and extracellular signal-regulated kinase 1/2.

Xiaoping Yang, J. Cleveland, Xiaoping Yang, 2009, The Journal of thoracic and cardiovascular surgery.

Secretory phospholipase A2 mediates human esophageal adenocarcinoma cell growth and proliferation via ERK 1/2 pathway.

M. Weyant, Xianzhong Meng, D. Fullerton, 2013, Anticancer research.

The Interaction Between HSP70 and TNF-&agr; Expression: A Novel Mechanism for Protection of the Myocardium Against Post-Injury Depression

A. Harken, Xianzhong Meng, 2002, Shock.

INTERLEUKIN‐10 STABILIZES INHIBITORY kB-α IN HUMAN MONOCYTES

A. Harken, D. Meldrum, Xianzhong Meng, 1998 .

Spinal Cord Ischemia-Reperfusion Injury Induces Erythropoietin Receptor Expression.

J. Cleveland, M. Weyant, Xianzhong Meng, 2015, The Annals of thoracic surgery.

Monocytes enhance the inflammatory response to TLR2 stimulation in aortic valve interstitial cells through paracrine up-regulation of TLR2 level

Balachandar Nedumaran, Xianzhong Meng, L. Ao, 2020, International journal of biological sciences.

Interleukin 37 Suppresses M1 Macrophage Polarization Through Inhibition of the Notch1 and Nuclear Factor Kappa B Pathways

Xianzhong Meng, Shaoyi Zheng, Daming Zuo, 2020, Frontiers in Cell and Developmental Biology.

Neutralization of IL-18 attenuates lipopolysaccharide-induced myocardial dysfunction.

R. McIntyre, A. Harken, C. Dinarello, 2002, American journal of physiology. Heart and circulatory physiology.

IL-37 Suppresses MyD88-mediated Inflammatory Responses in Human Aortic Valve Interstitial Cells

C. Dinarello, Xianzhong Meng, D. Fullerton, 2017, Molecular medicine.

Activation of TLR3 Induces Osteogenic Responses in Human Aortic Valve Interstitial Cells through the NF-κB and ERK1/2 Pathways

Xianzhong Meng, L. Ao, D. Fullerton, 2015, International journal of biological sciences.

Critical role of extracellular heat shock cognate protein 70 in the myocardial inflammatory response and cardiac dysfunction after global ischemia-reperfusion.

J. Cleveland, Xianzhong Meng, L. Ao, 2008, American journal of physiology. Heart and circulatory physiology.

THERAPEUTIC IMPLICATIONS OF INTERLEUKIN‐10 IN SURGICAL DISEASE

A. Harken, Xianzhong Meng, B. Shames, 1998, Shock.

Cancer stem cell phenotype is supported by secretory phospholipase A2 in human lung cancer cells.

M. Weyant, Xianzhong Meng, D. Fullerton, 2014, The Annals of thoracic surgery.

Activation state of stromal inflammatory cells in murine metastatic pancreatic adenocarcinoma.

E. Moore, C. Silliman, Xianzhong Meng, 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

Enhanced inflammatory responses to toll-like receptor 2/4 stimulation in type 1 diabetic coronary artery endothelial cells: the effect of insulin

J. Cleveland, Xianzhong Meng, L. Ao, 2010, Cardiovascular diabetology.

Inhibition of Myocardial TNF‐α Production by Heat Shock: A Potential Mechanism of Stress‐Induced Cardioprotection against Postischemic Dysfunction a

A. Harken, D. Meldrum, Xianzhong Meng, 1999, Annals of the New York Academy of Sciences.

Lung cancer cell invasion and expression of intercellular adhesion molecule-1 (ICAM-1) are attenuated by secretory phospholipase A₂ inhibition.

M. Weyant, Xianzhong Meng, L. Ao, 2012, The Journal of thoracic and cardiovascular surgery.

Signal Divergence and Convergence in Cardiac Adaptation

C. Cairns, E. Moore, A. Harken, 1998 .

Inhibition of secretory phospholipase A2 IIa attenuates prostaglandin E2-induced invasiveness in lung adenocarcinoma

M. Weyant, J. Rove, Xianzhong Meng, 2019, Molecular and Cellular Biochemistry.

Inhibition of secretory phospholipase A2 IIa attenuates prostaglandin E2-induced invasiveness in lung adenocarcinoma

M. Weyant, J. Rove, Xianzhong Meng, 2019, Molecular and Cellular Biochemistry.

Group IIa secretory phospholipase expression correlates with group IIa secretory phospholipase inhibition-mediated cell death in K-ras mutant lung cancer cells.

M. Weyant, R. Nemenoff, Xianzhong Meng, 2012, The Journal of thoracic and cardiovascular surgery.

Knockdown of secretory phospholipase A2 IIa reduces lung cancer growth in vitro and in vivo.

M. Weyant, R. Nemenoff, Xianzhong Meng, 2012, The Journal of thoracic and cardiovascular surgery.

Group IIa sPLA2 inhibition attenuates NF-κB activity and promotes apoptosis of lung cancer cells.

M. Weyant, Xianzhong Meng, D. Fullerton, 2012, Anticancer research.

Secretory phospholipase A2 inhibition attenuates intercellular adhesion molecule-1 expression in human esophageal adenocarcinoma cells.

F. Grover, M. Weyant, Xianzhong Meng, 2011, The Annals of thoracic surgery.

Lack of TNF-α attenuates intimal hyperplasia after mouse carotid artery injury

A. Harken, Xianzhong Meng, C. Selzman, 2002 .

Mechanistic Roles of Matrilin-2 and Klotho in Modulating the Inflammatory Activity of Human Aortic Valve Cells

Xianzhong Meng, L. Ao, D. Fullerton, 2020, Cells.

Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice

J. Cleveland, T. McKinsey, C. Dinarello, 2017, Proceedings of the National Academy of Sciences.

ADAMTS5 Deficiency in Calcified Aortic Valves Is Associated With Elevated Pro-Osteogenic Activity in Valvular Interstitial Cells

J. Cleveland, Xianzhong Meng, L. Ao, 2017, Arteriosclerosis, thrombosis, and vascular biology.

Aortic valve calcification is mediated by a differential response of aortic valve interstitial cells to inflammation.

M. Weyant, Xianzhong Meng, D. Fullerton, 2014, The Journal of surgical research.

Lysophosphatidylcholine activates the Akt pathway to upregulate extracellular matrix protein production in human aortic valve cells.

Xianzhong Meng, D. Fullerton, Qingzhou Yao, 2017, The Journal of surgical research.

Complement up-regulates Runx-2 to induce pro-fibrogenic change in aortic valve interstitial cells.

Xianzhong Meng, J. Jaggers, D. Fullerton, 2021, The Annals of thoracic surgery.

Autophagy negatively regulates pro-osteogenic activity in human aortic valve interstitial cells.

Xianzhong Meng, J. Jaggers, D. Fullerton, 2017, The Journal of surgical research.

Wnt Signaling Mediates Pro-Fibrogenic Activity in Human Aortic Valve Interstitial Cells.

M. Weyant, Xianzhong Meng, A. Houk, 2020, The Annals of thoracic surgery.

LPS-Induced NF-κB Activation and TNF-α Release in Human Monocytes Are Protein Tyrosine Kinase Dependent and Protein Kinase C Independent

R. McIntyre, A. Harken, D. Meldrum, 1999 .

DITPA, a thyroid hormone analog, reduces infarct size and attenuates the inflammatory response following myocardial ischemia.

Xianzhong Meng, L. Ao, Jilin Li, 2011, The Journal of surgical research.

ASSOCIATION FOR ACADEMIC SURGERY DITPA, AThyroid Hormone Analog, Reduces Infarct Size and Attenuates the Inflammatory Response Following Myocardial Ischemia

Xianzhong Meng, L. Ao, Jilin Li, 2011 .

NITRIC OXIDE SYNTHASE IS NOT INVOLVED IN CARDIAC CONTRACTILE DYSFUNCTION IN A RAT MODEL OF ENDOTOXEMIA WITHOUT SHOCK

A. Harken, Xianzhong Meng, L. Ao, 1997, Shock.

TISSUE‐SPECIFIC PROTEIN KINASE C ISOFORMS DIFFERENTIALLY MEDIATE MACROPHAGE TNFα AND IL‐1β PRODUCTION

R. McIntyre, A. Harken, D. Meldrum, 1998 .

Neurotrophin 3 upregulates proliferation and collagen production in human aortic valve interstitial cells: a potential role in aortic valve sclerosis.

J. Cleveland, Xianzhong Meng, L. Ao, 2017, American journal of physiology. Cell physiology.

Rapamycin Decreases the Osteogenic Response in Aortic Valve Interstitial Cells Through the Stat3 Pathway.

Xianzhong Meng, J. Jaggers, D. Fullerton, 2016, The Annals of thoracic surgery.

Lipopolysaccharide stimulation of human aortic valve interstitial cells activates inflammation and osteogenesis.

J. Cleveland, M. Weyant, Xiaoping Yang, 2008, The Annals of thoracic surgery.

C-terminal tensin-like protein mediates invasion of human lung cancer cells and is regulated by signal transducer and activator of transcription 3.

M. Weyant, Xianzhong Meng, D. Fullerton, 2015, The Journal of thoracic and cardiovascular surgery.

Post-transcriptional regulation of TNF-induced expression of ICAM-1 and IL-8 in human lung microvascular endothelial cells: an obligatory role for the p38 MAPK-MK2 pathway dissociated with HSP27.

Xiaoping Yang, Xianzhong Meng, L. Ao, 2008, Biochimica et biophysica acta.

Secretory Phospholipase A2 IIa Mediates Expression of Growth Factor Receptors in Esophageal Adenocarcinoma

M. McCarter, M. Weyant, Xianzhong Meng, 2020, Digestive Diseases and Sciences.

Glypican 1 promotes proliferation and migration in esophagogastric adenocarcinoma via activating AKT/GSK/β-catenin pathway

M. Weyant, Lindsey Westbrook, Xianzhong Meng, 2022, Journal of gastrointestinal oncology.

Warfarin Induces Calcification of the Aortic Valve via ERK1/2 and β-Catenin Signaling.

M. Weyant, Xianzhong Meng, D. Fullerton, 2021, The Annals of thoracic surgery.

Expression of Adhesion Molecules in a Gastroduodenal Reflux Murine Model.

M. Weyant, Xianzhong Meng, D. Fullerton, 2021, The Annals of thoracic surgery.

Complement Cross Talks With H-K-ATPase to Upregulate Runx2 in Human Aortic Valve Interstitial Cells.

Xianzhong Meng, J. Jaggers, D. Fullerton, 2023, The Journal of surgical research.

Pro-inflammatory mediators released by activated monocytes promote aortic valve fibrocalcific activity

Xianzhong Meng, L. Ao, D. Fullerton, 2022, Molecular medicine.

Interleukin-37 monomer is the active form for reducing innate immunity

E. Eisenmesser, J. Redzic, J. Kieft, 2019, Proceedings of the National Academy of Sciences.

Attenuation of spinal cord ischemia and reperfusion injury by erythropoietin.

J. Cleveland, M. Weyant, Xianzhong Meng, 2011, The Journal of thoracic and cardiovascular surgery.

Interleukin‐37 suppresses the inflammatory response to protect cardiac function in old endotoxemic mice

C. Dinarello, Xianzhong Meng, L. Ao, 2017, Cytokine.

Up-regulation of Myocardial Klotho Expression to Promote Cardiac Functional Recovery in Old Mice following Endotoxemia

Xianzhong Meng, L. Ao, D. Fullerton, 2023, Research square.

Soluble biglycan induces the production of ICAM-1 and MCP-1 in human aortic valve interstitial cells through TLR2/4 and the ERK1/2 pathway

Xianzhong Meng, L. Ao, D. Fullerton, 2014, Inflammation Research.

Attenuated Recovery of Contractile Function in Aging Hearts Following Global Ischemia/Reperfusion: Role of Extracellular HSP27 and TLR4

J. Cleveland, Xianzhong Meng, L. Ao, 2016, Molecular medicine.

Interleukin 6 production during cardiac surgery correlates with increasing age.

J. Cleveland, R. Schwartz, Xianzhong Meng, 2016, The Journal of surgical research.

Statin therapy attenuates growth and malignant potential of human esophageal adenocarcinoma cells.

M. Weyant, Xianzhong Meng, D. Fullerton, 2011, The Journal of thoracic and cardiovascular surgery.

Toll-like receptor 4 mediates oxidized - LDL induced macrophage differentiation to foam cells

Xianzhong Meng, L. Ao, D. Fullerton, 2010 .

Activation of Toll-Like Receptor 2 Promotes Proliferation of Human Lung Adenocarcinoma Cells

M. Weyant, Xianzhong Meng, D. Fullerton, 2020, AntiCancer Research.

Abstract 8603: Expression of Human Interleukine-37 Protects Mouse Heart Against Ischemic Injury Through Suppression of Monocyte Chemoattractant Protein-1-Mediated Mononuclear Cell Accumulation

C. Dinarello, Xianzhong Meng, L. Ao, 2011, Circulation.

Ligation of ICAM-1 on human aortic valve interstitial cells induces the osteogenic response: A critical role of the Notch1-NF-κB pathway in BMP-2 expression.

Xianzhong Meng, L. Ao, D. Fullerton, 2014, Biochimica et biophysica acta.

Ischemic preconditioning decreases postischemic myocardial tumor necrosis factor-alpha production. Potential ultimate effector mechanism of preconditioning.

A. Harken, D. Meldrum, C. Dinarello, 1998, Circulation.

Increased myocardial tumor necrosis factor-alpha in a crystalloid-perfused model of cardiac ischemia-reperfusion injury.

A. Harken, D. Meldrum, Xianzhong Meng, 1998, The Annals of thoracic surgery.

Spinal cord protection via alpha-2 agonist-mediated increase in glial cell-line-derived neurotrophic factor.

J. Cleveland, M. Weyant, Xianzhong Meng, 2015, The Journal of thoracic and cardiovascular surgery.

L-arginine attenuates lipopolysaccharide-induced lung chemokine production.

R. McIntyre, J. Heimbach, Xianzhong Meng, 2001, American journal of physiology. Lung cellular and molecular physiology.

IL-1 regulates in vivo C—X—C chemokine induction and neutrophil sequestration following endotoxemia

R. McIntyre, E. Abraham, C. Dinarello, 2002, Journal of endotoxin research.

Preconditioning of isolated rat heart is mediated by protein kinase C.

A. Harken, Xianzhong Meng, L. Ao, 1995, Circulation research.

Surgical implications of vascular endothelial physiology.

A. Harken, D. Meldrum, Xianzhong Meng, 1997, Surgery.

Tumor necrosis factor-alpha and interleukin-1beta synergistically depress human myocardial function.

A. Harken, D. Meldrum, C. Dinarello, 1999, Critical care medicine.

Adenosine reduces cardiac TNF-alpha production and human myocardial injury following ischemia-reperfusion.

A. Harken, D. Meldrum, C. Dinarello, 1998, The Journal of surgical research.

Human SERCA2a levels correlate inversely with age in senescent human myocardium.

J. Cleveland, A. Harken, D. Meldrum, 1998, Journal of the American College of Cardiology.

P504Critical role IL-37 to ameliorate endotoxemic cardiac depression in aging mice: a critical role of suppression cardiodepressant cytokines

C. Dinarello, Xianzhong Meng, L. Ao, 2014 .

Gastroduodenal reflux induces group IIa secretory phospholipase A(2) expression and activity in murine esophagus.

M. Weyant, Xiaoping Yang, Xianzhong Meng, 2010, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus.

Recombinant IL-37 Exerts an Anti-inflammatory Effect on Human Aortic Valve Interstitial Cells through Extracellular and Intracellular Actions

C. Dinarello, Xianzhong Meng, L. Ao, 2023, International journal of biological sciences.

Nitric oxide downregulates lung macrophage inflammatory cytokine production.

R. McIntyre, F. Grover, A. Harken, 1998, The Annals of thoracic surgery.

Norepinephrine induces cardiac heat shock protein 70 and delayed cardioprotection in the rat through alpha 1 adrenoceptors.

A. Harken, Xianzhong Meng, L. Ao, 1996, Cardiovascular research.

TLR4 mediates LPS-induced HO-1 expression in mouse liver: role of TNF-alpha and IL-1beta.

A. Harken, Xianzhong Meng, L. Ao, 2003, World journal of gastroenterology.

Silencing Glypican-1 enhances the antitumor effects of Pictilisib via downregulating PI3K/Akt/ERK signaling in chemo-resistant esophageal adenocarcinoma

M. McCarter, Lindsey Westbrook, Xianzhong Meng, 2023, Molecular & cellular oncology.

Targeting Glypican-1 Reverses Resistance to 5-Fluorouracil in Esophageal Adenocarcinoma Cells

Xianzhong Meng, S. Wani, R. Meguid, 2023, AntiCancer Research.

Neutrophil depletion attenuates endotoxin-induced dysfunction of cGMP-mediated pulmonary vasorelaxation.

R. McIntyre, D. Meldrum, Xianzhong Meng, 1996, The American journal of physiology.

Attenuated Recovery of Contractile Function in Aging Hearts Following Global Ischemia/Reperfusion: Role of Extracellular HSP27 and TLR4

J. Cleveland, Xianzhong Meng, L. Ao, 2016, Molecular medicine.

Neurotrophin 3 upregulates proliferation and collagen production in human aortic valve interstitial cells: a potential role in aortic valve sclerosis.

J. Cleveland, Xianzhong Meng, L. Ao, 2017, American journal of physiology. Cell physiology.

Increased levels of myocardial IκB-α protein promote tolerance to endotoxin.

A. Harken, D. Meldrum, Xianzhong Meng, 1998, American journal of physiology. Heart and circulatory physiology.

Enhanced inflammatory responses to toll-like receptor 2/4 stimulation in type 1 diabetic coronary artery endothelial cells: the effect of insulin

J. Cleveland, Xianzhong Meng, L. Ao, 2010, Cardiovascular diabetology.

Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: role of Smad1 and extracellular signal-regulated kinase 1/2.

J. Cleveland, Xiaoping Yang, Xianzhong Meng, 2009, The Journal of thoracic and cardiovascular surgery.

Plasma from stored packed red blood cells and MHC class I antibodies causes acute lung injury in a 2-event in vivo rat model.

E. Moore, C. Silliman, Xianzhong Meng, 2009, Blood.

Biglycan Induces the Expression of Osteogenic Factors in Human Aortic Valve Interstitial Cells via Toll-Like Receptor-2

J. Cleveland, Xianzhong Meng, L. Ao, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Activation state of stromal inflammatory cells in murine metastatic pancreatic adenocarcinoma.

E. Moore, C. Silliman, Xianzhong Meng, 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

Reactive Oxygen Species Mediate Nicorandil-induced Metabolic Tolerance to Spinal Cord Injury.

J. Cleveland, M. Weyant, Xianzhong Meng, 2020, The Annals of thoracic surgery.

Lack of TNF-alpha attenuates intimal hyperplasia after mouse carotid artery injury.

A. Harken, Xianzhong Meng, C. Selzman, 2002, American journal of physiology. Regulatory, integrative and comparative physiology.

The 5-Lipoxygenase Pathway Is Required for Acute Lung Injury Following Hemorrhagic Shock

E. Moore, R. Murphy, S. Zarini, 2012, Shock.

Aging exacerbates cardiac dysfunction and mortality in sepsis through enhancing TLR2 activity

Xianzhong Meng, L. Ao, Erlinda The, 2023, Frontiers in Cardiovascular Medicine.

ENDOTOXIN STUNS cGMP‐MEDIATED PULMONARY VASORELAXATION

R. McIntyre, D. Meldrum, Xianzhong Meng, 1997, Shock.

Molecular Interaction of Soluble Klotho with FGF23 in the Pathobiology of Aortic Valve Lesions Induced by Chronic Kidney Disease

Xianzhong Meng, L. Ao, Erlinda The, 2024, International journal of biological sciences.