P. Knuefermann

发表

Cardiac inflammation and innate immunity in septic shock: is there a role for toll-like receptors?

N. Sivasubramanian, B. Carabello, P. Knuefermann, 2002, Chest.

Toll-like receptor 4 deficiency: Smaller infarcts, but nogain in function

A. Hoeft, Se-Chan Kim, A. Ghanem, 2007, BMC physiology.

Toll‐like receptor 4 modulates myocardial ischaemia–reperfusion injury: Role of matrix metalloproteinases

A. Hoeft, Se-Chan Kim, C. Grohé, 2006, European journal of heart failure.

Anti-atherogenic effects of statins: Impact on angiopoietin-2 release from endothelial cells.

S. Klaschik, A. Hoeft, P. Knuefermann, 2013, Biochemical pharmacology.

Role of CD 14 in the Induction of Myocardial TNF and IL-1 After LPS Challenge

D. Mann, B. Carabello, S. Goyert, 2002 .

CD14-Deficient Mice Are Protected Against Lipopolysaccharide-Induced Cardiac Inflammation and Left Ventricular Dysfunction

D. Mann, B. Carabello, S. Goyert, 2002, Circulation.

Antibiotics regulate the immune response in both presence and absence of lipopolysaccharide through modulation of Toll-like receptors, cytokine production and phagocytosis in vitro.

A. Hoeft, B. Diedrich, P. Knuefermann, 2014, International immunopharmacology.

Toll-like receptor 4 deficiency: Smaller infarcts, but nogain in function

A. Hoeft, Se-Chan Kim, A. Ghanem, 2007, BMC Physiology.

Induction of p53 by GKLF is essential for inhibition of proliferation of vascular smooth muscle cells.

G. Nickenig, P. Knuefermann, U. Becher, 2007, Journal of molecular and cellular cardiology.

Myotrophin/V-1, a Protein Up-regulated in the Failing Human Heart and in Postnatal Cerebellum, Converts NFκB p50-p65 Heterodimers to p50-p50 and p65-p65 Homodimers*

N. Sivasubramanian, M. Abdellatif, P. Knuefermann, 2002, The Journal of Biological Chemistry.

A stop codon polymorphism of toll-like receptor 5 is associated with a stable course of chronic obstructive lung disease

A. Gillissen, C. Grohé, P. Knuefermann, 2006, European Respiratory Review.

Gender differences in the expression of heat shock proteins: the effect of estrogen.

J. N. Stallone, P. Knuefermann, R. Cornelussen, 2003, American journal of physiology. Heart and circulatory physiology.

Cytokines as emerging targets in the treatment of heart failure.

D. Mann, P. Knuefermann, G. Baumgarten, 2000, Trends in cardiovascular medicine.

Development of murine ischemic cardiomyopathy is associated with a transient inflammatory reaction and depends on reactive oxygen species

J. Crapo, M. Entman, G. Taffet, 2003, Proceedings of the National Academy of Sciences of the United States of America.

The role of innate immune responses in the heart in health and disease.

D. Mann, P. Knuefermann, J. Vallejo, 2004, Trends in cardiovascular medicine.

Myocardial cytokine gene expression is higher in aortic stenosis than in idiopathic dilated cardiomyopathy

W. Paulus, D. Mann, N. Sivasubramanian, 2005, Heart.

Group B Streptococcus Induces TNF-α Gene Expression and Activation of the Transcription Factors NF-κB and Activator Protein-1 in Human Cord Blood Monocytes1

D. Mann, N. Sivasubramanian, P. Knuefermann, 2000, The Journal of Immunology.

Tlr2 deficiency does not limit the development of left ventricular hypertrophy in a model of transverse aortic constriction induced pressure overload

P. Knuefermann, G. Baumgarten, R. Meyer, 2016, Journal of Negative Results in BioMedicine.

Brief murine myocardial I/R induces chemokines in a TNF-alpha-independent manner: role of oxygen radicals.

M. Entman, D. Mann, L. Michael, 2001, American journal of physiology. Heart and circulatory physiology.

Functional significance of inflammatory mediators in a murine model of resuscitated hemorrhagic shock.

D. Mann, D. Tweardy, P. Knuefermann, 2005, American journal of physiology. Heart and circulatory physiology.

The Heat Shock Paradox and Cardiac Myocytes: Role of Heat Shock Factor

Eunjung Kim, Se-Chan Kim, P. Knuefermann, 2011, Shock.

Toll-like receptor 4 deficiency: smaller infarcts, but no gain in function.

A. Hoeft, Se-Chan Kim, A. Ghanem, 2007 .

Nuclear Factor- (cid:1) B Protects the Adult Cardiac Myocyte Against Ischemia-Induced Apoptosis in a Murine Model of Acute Myocardial Infarction

M. Entman, E. Olson, Zhijian J. Chen, 2003 .

Nuclear Factor- (cid:1) B Protects the Adult Cardiac Myocyte Against Ischemia-Induced Apoptosis in a Murine Model of Acute Myocardial Infarction

M. Entman, E. Olson, D. Mann, 2003 .

Toll-Like Receptor 2 Mediates Staphylococcus aureus–Induced Myocardial Dysfunction and Cytokine Production in the Heart

S. Akira, O. Takeuchi, Y. Sakata, 2004, Circulation.

In vivo expression of proinflammatory mediators in the adult heart after endotoxin administration: the role of toll-like receptor-4.

D. Mann, N. Sivasubramanian, P. Knuefermann, 2001, The Journal of infectious diseases.

Escherichia coli LPS-induced LV dysfunction: role of toll-like receptor-4 in the adult heart.

D. Mann, B. Carabello, P. Knuefermann, 2002, American journal of physiology. Heart and circulatory physiology.

TOLL-LIKE RECEPTOR 4, NITRIC OXIDE, AND MYOCARDIAL DEPRESSION IN ENDOTOXEMIA

A. Hoeft, C. Grohé, V. Vervölgyi, 2006, Shock.

Bacterial DNA induces myocardial inflammation and reduces cardiomyocyte contractility: role of toll-like receptor 9.

A. Hoeft, C. Grohé, K. Zacharowski, 2008, Cardiovascular research.

Myocardial injury modulates the innate immune system and changes myocardial sensitivity

A. Hoeft, Se-Chan Kim, C. Grohé, 2006, Basic Research in Cardiology.

[Cytokines and heart failure].

A. Hoeft, C. Grohé, P. Knuefermann, 2004, Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS.

RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study: Myocardial Dysfunction, Postoperative Neurocognitive Dysfunction, and 1 Year Follow‐Up

J. Scholz, A. Hoeft, C. Werner, 2018, Journal of the American Heart Association.

Remote ischaemic preconditioning for heart surgery. The study design for a multi-center randomized double-blinded controlled clinical trial--the RIPHeart-Study.

C. Werner, D. Hasenclever, B. Bein, 2012, European heart journal.

Toll-Like Receptor 9 Promotes Cardiac Inflammation and Heart Failure during Polymicrobial Sepsis

A. Hoeft, G. Duerr, P. Knuefermann, 2013, Mediators of inflammation.

In Vivo Toll-Like Receptor 4 Antagonism Restores Cardiac Function During Endotoxemia

P. Knuefermann, G. Baumgarten, R. Meyer, 2011, Shock.

CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo

A. Hoeft, C. Grohé, K. Zacharowski, 2007, Respiratory research.

Toll-Like Receptor 2 Mediates Staphylococcus aureus –Induced Myocardial Dysfunction and Cytokine Production in the Heart Molecular Cardiology

S. Akira, O. Takeuchi, K. Sekiguchi, 2004 .

Sepsis-induced vasoplegia--is vasopressin V1A-receptor a new target?

K. Zacharowski, P. Knuefermann, G. Baumgarten, 2008, Critical care medicine.

Myotrophin/V-1 does not act as an extracellular signal to induce myocyte hypertrophy.

N. Sivasubramanian, P. Knuefermann, G. Baumgarten, 2006, Texas Heart Institute journal.

Postconditioning with a CpG containing oligodeoxynucleotide ameliorates myocardial infarction in a murine closed-chest model.

A. Hoeft, Se-Chan Kim, P. Knuefermann, 2014, Life sciences.

In Vivo TLR9 Inhibition Attenuates CpG-Induced Myocardial Dysfunction

A. Hoeft, P. Knuefermann, G. Baumgarten, 2013, Mediators of inflammation.

Sinus venous thrombosis: a differential diagnosis of postpartum headache

H. Urbach, P. Knuefermann, G. Baumgarten, 2011, Archives of Gynecology and Obstetrics.

Inactivation of Ets 1 transcription factor by a specific decoy strategy reduces rat C6 glioma cell proliferation and mmp-9 expression.

T. Pietsch, P. Knuefermann, A. Okuducu, 2005, International journal of molecular medicine.

Group B StreptococcusInduces TNF-a Gene Expression and Activation of the Transcription Factors NF-kB and Activator Protein-1 in Human Cord Blood Monocytes

D. Mann, N. Sivasubramanian, P. Knuefermann, 2000 .

TLR2 stimulation induces cardiac inflammation but not cardiac depression in vivo

A. Hoeft, C. Grohé, K. Zacharowski, 2013, Journal of Inflammation.

Antifungal antibiotics modulate the pro-inflammatory cytokine production and phagocytic activity of human monocytes in an in vitro sepsis model.

A. Hoeft, B. Diedrich, P. Knuefermann, 2015, Life sciences.

Improve hip fracture outcome in the elderly patient (iHOPE): a study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia

A. Hoeft, M. Bajbouj, R. Rossaint, 2018, BMJ Open.

Group B Streptococcus induces TNF-alpha gene expression and activation of the transcription factors NF-kappa B and activator protein-1 in human cord blood monocytes.

D. Mann, N. Sivasubramanian, P. Knuefermann, 2000, Journal of immunology.

Toll-like receptor 9 expression in murine and human adrenal glands and possible implications during inflammation.

S. Lightman, S. Bornstein, K. Zacharowski, 2007, The Journal of clinical endocrinology and metabolism.

Systemically Administered Ligands of Toll-Like Receptor 2, -4, and -9 Induce Distinct Inflammatory Responses in the Murine Lung

C. Grohé, P. Knuefermann, G. Baumgarten, 2011, Mediators of inflammation.

Synthetic CpG oligonucleotides induce a genetic profile ameliorating murine myocardial I/R injury

S. Klaschik, A. Hoeft, P. Knuefermann, 2018, Journal of cellular and molecular medicine.

Vascular Dysfunction following Polymicrobial Sepsis: Role of Pattern Recognition Receptors

A. Hoeft, P. Knuefermann, G. Baumgarten, 2012, PloS one.

TLR2 stimulation induces cardiac inflammation but not cardiac depression in vivo

A. Hoeft, C. Grohé, K. Zacharowski, 2013, Journal of Inflammation.

Low-tidal-volume prevent ventilation induced inflammation in a mouse model of sepsis.

G. Duerr, P. Knuefermann, G. Baumgarten, 2019, Life sciences.

Toll-like receptor 4 plays a crucial role in the immune-adrenal response to systemic inflammatory response syndrome.

S. Bornstein, K. Schulze-Osthoff, K. Zacharowski, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Ultrasound confirmation of central venous catheter position via a right supraclavicular fossa view using a microconvex probe: An observational pilot study

A. Hoeft, Se-Chan Kim, P. Knuefermann, 2015, European journal of anaesthesiology.

Load-Dependent and -Independent Regulation of Proinflammatory Cytokine and Cytokine Receptor Gene Expression in the Adult Mammalian Heart

P. Blackshear, F. Gao, G. Taffet, 2002, Circulation.

The toll‐like receptor 4‐antagonist eritoran reduces murine cardiac hypertrophy

P. Knuefermann, G. Baumgarten, R. Meyer, 2011, European journal of heart failure.

Role of Toll‐like receptor 4 for the pathogenesis of acute lung injury in Gram‐negative sepsis

A. Hoeft, C. Putensen, C. Grohé, 2006, European journal of anaesthesiology.

Pre-conditioning with synthetic CpG-oligonucleotides attenuates myocardial ischemia/reperfusion injury via IL-10 up-regulation

S. Klaschik, A. Hoeft, K. Zacharowski, 2013, Basic Research in Cardiology.

Priming with synthetic oligonucleotides attenuates pressure overload-induced inflammation and cardiac hypertrophy in mice.

S. Klaschik, A. Hoeft, G. Duerr, 2012, Cardiovascular research.

Decreased Secondary Lesion Growth and Attenuated Immune Response after Traumatic Brain Injury in Tlr2/4−/− Mice

N. Plesnila, Florian Voigt, S. Krieg, 2017, Front. Neurol..

Nuclear factor-kappaB protects the adult cardiac myocyte against ischemia-induced apoptosis in a murine model of acute myocardial infarction.

M. Entman, E. Olson, Zhijian J. Chen, 2003, Circulation.

A "small" defect with malignant effect.

G. Nickenig, P. Knuefermann, C. Hammerstingl, 2011, Journal of the American College of Cardiology.

Antibiotics regulate the immune response in both presence and absence of lipopolysaccharide through modulation of Toll-like receptors, cytokine production and phagocytosis in vitro.

A. Hoeft, B. Diedrich, P. Knuefermann, 2014, International Immunopharmacology.

, and Cytokine Production in the Heart Induced Myocardial Dysfunction − Staphylococcus aureus Toll-Like Receptor 2 Mediates

S. Akira, O. Takeuchi, Y. Sakata, 2004 .

[Cardiopulmonary bypass in cardiac surgery].

A. Hoeft, P. Knuefermann, G. Baumgarten, 2012, Der Anaesthesist.