P. Grammas

发表

Endotoxin and thrombin elevate rodent endothelial cell protein C receptor mRNA levels and increase receptor shedding in vivo.

C. Esmon, J. Gu, Y. Katsuura, 2000, Blood.

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

A. Fagan, M. Weiner, T. Montine, 2015, Alzheimer's & Dementia.

Blood-based biomarkers in Alzheimer disease: Current state of the science and a novel collaborative paradigm for advancing from discovery to clinic

P. Snyder, H. Vanderstichele, P. Lewczuk, 2017, Alzheimer's & Dementia.

Validation of a serum screen for Alzheimer's disease across assay platforms, species, and tissues.

Guanghua Xiao, Fan Zhang, Ryan M Huebinger, 2014, Journal of Alzheimer's disease : JAD.

Angiogenic proteins are expressed by brain blood vessels in Alzheimer's disease.

P. Grammas, A. Owoso, L. Thirumangalakudi, 2006, Journal of Alzheimer's disease : JAD.

Thrombin, a mediator of cerebrovascular inflammation in AD and hypoxia

P. Grammas, X. Yin, D. Tripathy, 2013, Front. Aging Neurosci..

VASCULAR-MEDIATED NEUROTOXICITY: A NOVEL TARGET FOR AD THERAPEUTICS

W. Renehan, P. Grammas, Joseph M. Martinez, 2017, Alzheimer's & Dementia.

Regulation of n‐3 and n‐6 Fatty Acid Metabolism in Retinal and Cerebral Microvascular Endothelial Cells by High Glucose

P. Grammas, R. E. Anderson, I. Delton-Vandenbroucke, 1998, Journal of neurochemistry.

Polyunsaturated fatty acid metabolism in retinal and cerebral microvascular endothelial cells.

P. Grammas, R. E. Anderson, I. Delton-Vandenbroucke, 1997, Journal of lipid research.

Thrombin Signaling Contributes to High Glucose-Induced Injury of Human Brain Microvascular Endothelial Cells.

S. W. Bihaqi, P. Grammas, H. Rao, 2020, Journal of Alzheimer's disease : JAD.

Sex Differences in Metabolic Indices and Chronic Neuroinflammation in Response to Prolonged High-Fat Diet in ApoE4 Knock-In Mice

P. Grammas, John K. Robinson, J. Iannucci, 2022, International journal of molecular sciences.

Multiple neurotrophic effects of VEGF on cultured neurons

P. Grammas, Alma C Sanchez, Suchin Wadhwani, 2010, Neuropeptides.

Rat heart-derived endothelial and smooth muscle cell cultures: isolation, cloning and characterization.

P. Grammas, C. Diglio, F. Giacomelli, 1988, Tissue & cell.

Transcriptional and posttranscriptional regulation of angiopoietin-2 expression mediated by IGF and PDGF in vascular smooth muscle cells.

P. Grammas, E. Howard, E. Phelps, 2006, American journal of physiology. Cell physiology.

Identification of Muscarinic Receptors in Rat Cerebral Cortical Microvessels

B. Marks, P. Grammas, C. Diglio, 1983, Journal of Neurochemistry.

The arachidonic acid 5‐lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor α activation of microglia and extends survival of G93A‐SOD1 transgenic mice

K. Hensley, Q. Pye, C. Stewart, 2004, Journal of neurochemistry.

Purification of endothelial cells from rat brain.

P. Grammas, X. Yin, D. Tripathy, 2014, Methods in molecular biology.

Hypoxia induces angiogenic factors in brain microvascular endothelial cells.

P. Grammas, D. Tripathy, Jinhua Luo, 2012, Microvascular research.

New perspectives on vitamin E: gamma-tocopherol and carboxyelthylhydroxychroman metabolites in biology and medicine.

R. Bolli, K. Hensley, Q. Pye, 2004, Free radical biology & medicine.

The effect of age and injury on the expression of inducible nitric oxide synthase in facial motor neurons in F344 rats

P. Grammas, J. M. Jacob, M. Dorheim, 1999, Mechanisms of Ageing and Development.

Short-term treatment with dabigatran alters protein expression patterns in a late-stage tau-based Alzheimer's disease mouse model

N. Seeram, P. Grammas, F. Akhlaghi, 2020, Biochemistry and biophysics reports.

Characterization of a γ‐glutamyl transpeptidase positive subpopulation of endothelial cells in a spontaneous tube‐forming clone of rat cerebral resistance‐vessel endothelium

P. Grammas, L. D. De Bault, Bao‐Le Wang, 1993, Journal of cellular physiology.

Targeting thrombin: an inflammatory neurotoxin in Alzheimer's disease.

P. Grammas, Joseph M. Martinez, 2014, Journal of Alzheimer's disease : JAD.

Aortic cholesterol accumulation correlates with systemic inflammation but not hepatic and gonadal adipose tissue inflammation in low-density lipoprotein receptor null mice.

A. Lichtenstein, Chwan-Li Shen, N. Moustaid‐Moussa, 2013, Nutrition research.

Effects of apigenin on steroidogenesis and steroidogenic acute regulatory gene expression in mouse Leydig cells.

A. Pandey, P. Grammas, D. Stocco, 2011, The Journal of nutritional biochemistry.

Chrysin, a natural flavonoid enhances steroidogenesis and steroidogenic acute regulatory protein gene expression in mouse Leydig cells.

R. Schiffer, A. Pandey, K. Jana, 2008, The Journal of endocrinology.

Message and protein-level elevation of tumor necrosis factor α (TNFα) and TNFα-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis

Scott Ferrell, K. Hensley, Q. Pye, 2003, Neurobiology of Disease.

Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis.

Scott Ferrell, K. Hensley, Q. Pye, 2003, Neurobiology of disease.

Anti-inflammatory effects of tocopherol metabolites.

K. Hensley, Q. Pye, C. Stewart, 2004, Biochemical and Biophysical Research Communications - BBRC.

New perspectives on vitamin E: γ-tocopherol and carboxyethylhydroxychroman metabolites in biology and medicine

R. Bolli, K. Hensley, Q. Pye, 2004 .

Anoxia/reoxygenation induces hydroxyl free radical formation in brain microvessels.

Guangheng Liu, R. Floyd, P. Grammas, 1993, Free radical biology & medicine.

Cerebrovascular expression of proteins related to inflammation, oxidative stress and neurotoxicity is altered with aging

P. Grammas, D. Tripathy, Alma C Sanchez, 2010, Journal of Neuroinflammation.

Determination of Biological Oxidative Stress Using High Performance Liquid Chromatography with Electrochemical Detection (HPLC‐ECD)

K. Hensley, R. Floyd, P. Grammas, 1999 .

Lipid content in hepatic and gonadal adipose tissue parallel aortic cholesterol accumulation in mice fed diets with different omega-6 PUFA to EPA plus DHA ratios.

A. Lichtenstein, Chwan-Li Shen, Dayong Wu, 2014, Clinical nutrition.

Is HIV involved in the pathogenesis of non-infectious pulmonary complications in infected patients?

R. Kennedy, P. Grammas, G. Kanmogne, 2003, Current HIV research.

Molecular Neuropsychology: Creation of Test-Specific Blood Biomarker Algorithms

R. Doody, K. Wilhelmsen, Guanghua Xiao, 2013, Dementia and Geriatric Cognitive Disorders.

Retinal endothelial cells are more susceptible to oxidative stress and increased permeability than brain-derived endothelial cells.

P. Grammas, Michael Riden, 2003, Microvascular research.

Analysis of human lung endothelial cells for susceptibility to HIV type 1 infection, coreceptor expression, and cytotoxicity of gp120 protein.

R. Kennedy, P. Grammas, G. Kanmogne, 2001, AIDS research and human retroviruses.

Isolation and characterization of cerebral resistance vessel endothelium in culture.

P. Grammas, W. Liu, C. Diglio, 1993, Tissue & cell.

Infection of baboon microglia with SIV-HIV recombinant viruses: role of CD4 and chemokine receptors.

R. Kennedy, P. Grammas, G. Kanmogne, 2002, AIDS research and human retroviruses.

Protein kinase C-ζ activity but not level is decreased in Alzheimer's disease microvessels

P. Grammas, P. Moore, V. Christiansen, 1998, Neuroscience Letters.

HIV-1 gp120 Proteins Alter Tight Junction Protein Expression and Brain Endothelial Cell Permeability: Implications for the Pathogenesis of HIV-Associated Dementia

P. Grammas, G. Kanmogne, Charles Primeaux, 2005, Journal of neuropathology and experimental neurology.

The cerebromicrovasculature: a key player in the pathogenesis of Alzheimer's disease.

B. Zlokovic, P. Grammas, M. Yamada, 2002, Journal of Alzheimer's disease : JAD.

Cerebrovasculature‐mediated Neuronal Cell Death

P. Weigel, P. Grammas, U. Reimann‐Philipp, 2000, Annals of the New York Academy of Sciences.

Primary culture of rat cerebral microvascular endothelial cells. Isolation, growth, and characterization.

P. Grammas, C. Diglio, F. Giacomelli, 1982, Laboratory investigation; a journal of technical methods and pathology.

A Primary Culture System of Rat Heart-Derived Endothelial Cells for Evaluating Cocaine-Induced Vascular Injury

P. Grammas, R. Melchert, R. Fugate, 1993 .

Cellular mechanisms of cocaine cardiotoxicity.

P. Grammas, R. Melchert, A. A. Welder, 1993, Toxicology letters.

Control of [3H]ouabain binding to cerebromicrovascular (Na+ + K+)-ATPase by metal ions and proteins.

P. Grammas, M. Caspers, T. Kwaiser, 1990, Biochemical pharmacology.

Acetaminophen protects brain endothelial cells against oxidative stress.

P. Grammas, D. Tripathy, Debjani Tripathy, 2009, Microvascular research.

Anoxic injury of endothelial cells causes divergent changes in protein kinase C and protein kinase A signaling pathways.

R. Floyd, P. Grammas, P. Moore, 1998, Molecular and chemical neuropathology.

Involvement of PGE2 and PGDH but not COX-2 in thrombin-induced cortical neuron apoptosis

P. Grammas, L. Thirumangalakudi, H. Rao, 2009, Neuroscience Letters.

Autonomic receptor characterization in cultured adult rat cardiac myocytes: morphologic-functional correlation.

P. Grammas, C. Diglio, F. Giacomelli, 1988, Journal of molecular and cellular cardiology.

Autonomic receptor interactions in isolated cardiac myocytes from hypertensive rats.

M. Dereski, P. Grammas, C. Diglio, 1989, Journal of molecular and cellular cardiology.

Short Communication Brain Endothelial Cells Synthesize Neurotoxic Thrombin in Alzheimer’s Disease

P. Grammas, Xiangling Yin, J. Wright, 2010 .

Oxidized LDLs affect nitric oxide and radical generation in brain endothelial cells.

K. Hensley, P. Grammas, A. Christov, 2003, Biochemical and biophysical research communications.

Gelatinase A expression in endothelial cells is regulated by at least two cis-acting promoter elements.

P. Grammas, T. Vu, E. Howard, 1999, Biochimica et biophysica acta.

Control of the Na+,K(+)-ATPase under normal and pathological conditions.

P. Grammas, M. Caspers, T. Kwaiser, 1993, Molecular and chemical neuropathology.

Effect of Fatty Acids on [3H]Ouabain Binding to Cerebromicrovascular (Na++ K+)‐ATPase

P. Grammas, M. Caspers, Paula Grammas, 1988, Journal of neurochemistry.

PACAP38 protects rat cortical neurons against the neurotoxicity evoked by sodium nitroprusside and thrombin

P. Grammas, Alma C Sanchez, H. Rao, 2009, Regulatory Peptides.

Rat cerebral microvascular smooth muscle cells in culture

P. Grammas, C. Diglio, F. Giacomelli, 1986, Journal of cellular physiology.

Differential glucose uptake in retina- and brain-derived endothelial cells.

A. Olson, P. Grammas, T. Rajah, 2001, Microvascular research.

Carotid artery constriction in acute hypertension.

P. Grammas, F. Giacomelli, J. Wiener, 1981, The American journal of pathology.

Inhibition of Thromboxane a Synthase Activity Enhances Steroidogenesis and Steroidogenic Acute Regulatory Gene Expression in Ma-10 Mouse Leydig Cells

R. Schiffer, P. Grammas, S. King, 2022 .

RANTES release contributes to the protective action of PACAP38 against sodium nitroprusside in cortical neurons

P. Grammas, D. Tripathy, Alma C Sanchez, 2009, Neuropeptides.

Alterations of cerebromicrovascular Na+, K+-ATPase activity due to fatty acids and acute hypertension

P. Grammas, L. Ulanski, M. Caspers, 1993, Brain Research.

Nitric oxide synthase activity is elevated in brain microvessels in Alzheimer's disease.

J. Pollock, P. Grammas, W. R. Tracey, 1994, Biochemical and biophysical research communications.

The involvement of epoxygenase metabolites of arachidonic acid in cAMP-stimulated steroidogenesis and steroidogenic acute regulatory protein gene expression.

R. Schiffer, Chwan-Li Shen, P. Grammas, 2006, The Journal of endocrinology.

The involvement of epoxygenase m etabolites of arachidonic acid in cAMP-stimulated steroidogenesis and steroidogenic acute regulatory protein gene expression

R. Schiffer, Chwan-Li Shen, P. Grammas, 2006 .

Growth properties and receptor expression in vascular smooth muscle cells from hypertensive rats.

P. Grammas, C. Diglio, F. Giacomelli, 1994, Clinical and experimental hypertension.

Structural changes in Alzheimer's disease brain microvessels.

P. Grammas, A. Christov, L. Hamdheydari, 2008, Current Alzheimer research.

Alzheimer disease amyloid proteins inhibit brain endothelial cell proliferation in vitro.

M. Ball, A. Roher, P. Grammas, 1995, Dementia.

Cerebral microvascular endothelium and the pathogenesis of neurodegenerative diseases

P. Grammas, Joseph M. Martinez, Paula Grammas, 2011, Expert Reviews in Molecular Medicine.

VEGF and VEGF receptor levels in retinal and brain-derived endothelial cells.

P. Grammas, T. Rajah, 2002, Biochemical and biophysical research communications.

Vascular inflammatory, oxidative and protease-based processes: implications for neuronal cell death in Alzheimer's disease

P. Grammas, A. Christov, J. Ottman, 2004, Neurological research.

Involvement of the thromboxane A2 receptor in the regulation of steroidogenic acute regulatory gene expression in murine Leydig cells.

R. Schiffer, A. Pandey, P. Grammas, 2009, Endocrinology.

Regulation of cerebrovascular γ-glutamyltranspeptidase by adrenergic and cholinergic agonists

P. Grammas, C. Diglio, F. Giacomelli, 1985 .

Cerebral microvessels in Alzheimer's have reduced protein kinase C activity

M. Ball, D. Cooper, A. Roher, 1995, Neurobiology of Aging.

Brain endothelial cells synthesize neurotoxic thrombin in Alzheimer's disease.

Jill Wright, P. Grammas, Xiangling Yin, 2010, The American journal of pathology.

Thrombin and inflammatory proteins are elevated in Alzheimer's disease microvessels: implications for disease pathogenesis.

P. Grammas, L. Thirumangalakudi, Pezhman Ghatreh Samany, 2006, Journal of Alzheimer's disease : JAD.

Thrombin, a Mediator of Coagulation, Inflammation, and Neurotoxicity at the Neurovascular Interface: Implications for Alzheimer’s Disease

W. Renehan, P. Grammas, J. Iannucci, 2020, Frontiers in Neuroscience.

Inhibiting thrombin improves motor function and decreases oxidative stress in the LRRK2 transgenic Drosophila melanogaster model of Parkinson's disease.

N. Seeram, P. Grammas, J. Iannucci, 2020, Biochemical and biophysical research communications.

Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease

P. Grammas, Paula Grammas, 2011, Journal of Neuroinflammation.

Microvessels from Alzheimer's disease brains kill neurons in vitro.

P. Weigel, P. Grammas, P. Moore, 1999, The American journal of pathology.

Cyclin D1, cdk4, and Bim are involved in thrombin‐induced apoptosis in cultured cortical neurons

P. Grammas, L. Thirumangalakudi, H. Rao, 2007, Journal of neurochemistry.

Calcium and the impairment of contractions to norepinephrine in aorta isolated from the spontaneously hypertensive rat.

P. Grammas, C. Diglio, D. Bessert, 1991, Clinical and experimental hypertension. Part A, Theory and practice.

Acetaminophen inhibits neuronal inflammation and protects neurons from oxidative stress

P. Grammas, D. Tripathy, 2009, Journal of Neuroinflammation.

Cyclin-C-dependent cell-cycle entry is required for activation of non-homologous end joining DNA repair in postmitotic neurons

M. Gorospe, P. Grammas, I. Kruman, 2010, Cell Death and Differentiation.

Cyclin C and cyclin dependent kinases 1, 2 and 3 in thrombin-induced neuronal cell cycle progression and apoptosis

P. Grammas, L. Thirumangalakudi, H. Rao, 2009, Neuroscience Letters.

Angiogenic Mediators and the Pathogenesis of Alzheimer’s Disease

P. Grammas, 2010 .

Inflammatory factors are elevated in brain microvessels in Alzheimer’s disease

P. Grammas, Roma Ovase, 2001, Neurobiology of Aging.

The Cstf2t Polyadenylation Gene Plays a Sex-Specific Role in Learning Behaviors in Mice

S. Bergeson, P. Grammas, C. MacDonald, 2016, PloS one.

Strategies to advance translational research into brain barriers

J. Nutt, W. Banks, D. Groothuis, 2008, The Lancet Neurology.

Isoform-Specific Effects of Apolipoprotein E on Markers of Inflammation and Toxicity in Brain Glia and Neuronal Cells In Vitro

P. Grammas, J. Iannucci, A. Sen, 2021, Current issues in molecular biology.

High Glucose and Hypoxia-Mediated Damage to Human Brain Microvessel Endothelial Cells Induces an Altered, Pro-Inflammatory Phenotype in BV-2 Microglia In Vitro

P. Grammas, H. Rao, J. Iannucci, 2020, Cellular and Molecular Neurobiology.

Expression of macrophage inflammatory protein 1-alpha is elevated in Alzheimer's vessels and is regulated by oxidative stress.

P. Grammas, L. Thirumangalakudi, D. Tripathy, 2007, Journal of Alzheimer's disease : JAD.

Analysis of human endothelial cells and cortical neurons for susceptibility to HIV-1 infection and co-receptor expression.

R. Kennedy, P. Grammas, G. Kanmogne, 2000, Journal of neurovirology.

CAP37, a neutrophil-derived inflammatory mediator, augments leukocyte adhesion to endothelial monolayers.

P. Grammas, Padmasini Kumar, H. Pereira, 2003, Microvascular research.

CAP37, a novel inflammatory mediator: its expression in endothelial cells and localization to atherosclerotic lesions.

P. Grammas, Padmasini Kumar, H. Pereira, 2002, The American journal of pathology.

Functional modulation of smooth muscle cells by the inflammatory mediator CAP37.

P. Grammas, Padmasini Kumar, H. Pereira, 2004, Microvascular research.

Regulation of protein kinase C activity in cerebral microvessels.

P. Grammas, P. Moore, K. Morgenstern, 1995, Molecular and chemical neuropathology.

Blood-Cerebrospinal Fluid Barrier Gradients in Mild Cognitive Impairment and Alzheimer's Disease: Relationship to Inflammatory Cytokines and Chemokines

Richard N. Jones, E. Stopa, S. M. de la Monte, 2018, Front. Aging Neurosci..

p38 MAPK: a mediator of hypoxia-induced cerebrovascular inflammation.

P. Grammas, D. Tripathy, Alma C Sanchez, 2012, Journal of Alzheimer's disease : JAD.

P. Grammas, D. Tripathy, Alma C Sanchez, 2012, Microvascular research.

A damaged microcirculation contributes to neuronal cell death in Alzheimer’s disease☆

P. Grammas, 2000, Neurobiology of Aging.

Oxidative stress impairs learning and memory in apoE knockout mice

P. Grammas, A. Young, M. Evola, 2010, Pharmacology Biochemistry and Behavior.

Gene expression profiling in Alzheimer's disease brain microvessels.

P. Grammas, U. Qaisar, Shu Wang, 2012, Journal of Alzheimer's disease : JAD.

Thrombin, a mediator of neurotoxicity and memory impairment

P. Grammas, Albert Nguyen, A. Adesina, 2004, Neurobiology of Aging.

A Precision Medicine Model for Targeted NSAID Therapy in Alzheimer's Disease.

C. Lyketsos, S. O'Bryant, J. Hall, 2018, Journal of Alzheimer's disease : JAD.

A new paradigm for the treatment of Alzheimer's disease: targeting vascular activation.

P. Grammas, A. Young, D. Tripathy, 2014, Journal of Alzheimer's disease : JAD.

Brain microvasculature and hypoxia-related proteins in Alzheimer's disease.

P. Grammas, D. Tripathy, Alma C Sanchez, 2011, International journal of clinical and experimental pathology.

Endothelin-1 is elevated in Alzheimer's disease brain microvessels and is neuroprotective.

P. Grammas, Jinhua Luo, 2010, Journal of Alzheimer's disease : JAD.

Insulin Resistance and Oligodendrocyte/Microvascular Endothelial Cell Dysfunction as Mediators of White Matter Degeneration in Alzheimer’s Disease

P. Grammas, S. Monte, 2019 .

Protein kinase C in rat cerebral microvessels.

D. Cooper, P. Grammas, K. Morgenstern, 1993, Molecular and chemical neuropathology.

Equol, a Blood–Brain Barrier Permeable Gut Microbial Metabolite of Dietary Isoflavone Daidzein, Exhibits Neuroprotective Effects against Neurotoxins Induced Toxicity in Human Neuroblastoma SH-SY5Y Cells and Caenorhabditis elegans

N. Seeram, P. Grammas, H. Park, 2020, Plant Foods for Human Nutrition.

Evaluating Thrombin Inhibition in Alzheimer’s Disease (The BEACON Trial): Protocol for a Pilot Study (Preprint)

S. Salloway, J. Machan, P. Grammas, 2019 .

RANTES upregulation in the Alzheimer's disease brain: A possible neuroprotective role

P. Grammas, L. Thirumangalakudi, D. Tripathy, 2010, Neurobiology of Aging.

Induction of apoptosis and endothelin-1 secretion in primary human lung endothelial cells by HIV-1 gp120 proteins.

P. Grammas, G. Kanmogne, Charles Primeaux, 2005, Biochemical and biophysical research communications.

Selective expression of c‐mas proto‐oncogene in rat cerebral endothelial cells

P. Grammas, F. Giacomelli, J. Wiener, 1996, Neuroreport.

The Nitration Product 5-Nitro-γ-tocopherol Is Increased in the Alzheimer Brain

W. Markesbery, K. Hensley, Q. Pye, 2002 .

cAMP-dependent protein kinase in cerebral microvessels in aging and Alzheimer disease.

P. Grammas, R. Cashman, 1995, Molecular and chemical neuropathology.

Increased accumulation of cAMP in cerebral microvessels in Alzheimer's disease

M. Ball, A. Roher, P. Grammas, 1994, Neurobiology of Aging.

Amyloid Beta and the Cerebral Vasculature

P. Grammas, 2005 .

Cerebrovascular transforming growth factor-beta contributes to inflammation in the Alzheimer's disease brain.

P. Grammas, Roma Ovase, 2002, The American journal of pathology.

CAP37, a neutrophil granule‐derived protein stimulates protein kinase C activity in endothelial cells

P. Grammas, P. Moore, H. Pereira, 1996, Journal of leukocyte biology.

Transduction of PACAP38 protects primary cortical neurons from neurotoxic injury

P. Grammas, Alma C Sanchez, M. Chiriva-Internati, 2008, Neuroscience Letters.

The nitration product 5-nitro-gamma-tocopherol is increased in the Alzheimer brain.

W. Markesbery, K. Hensley, Q. Pye, 2002, Nitric oxide : biology and chemistry.

Neurodegeneration and the Brain Barriers Contributors

J. Nutt, E. Stopa, B. Zlokovic, 2007 .

Neurovascular unit and the effects of dosage in VEGF toxicity: role for oxidative stress and thrombin.

P. Grammas, D. Tripathy, Alma C Sanchez, 2013, Journal of Alzheimer's disease : JAD.

Thrombin, a Key Driver of Pathological Inflammation in the Brain

P. Grammas, J. Iannucci, 2023, Cells.

Vascular signaling abnormalities in Alzheimer disease

P. Grammas, D. Tripathy, Alma C Sanchez, 2011, Cleveland Clinic Journal of Medicine.

HIV‐1 gp120 Proteins and gp160 Peptides Are Toxic to Brain Endothelial Cells and Neurons: Possible Pathway for HIV Entry into the Brain and HIV‐Associated Dementia

R. Kennedy, P. Grammas, G. Kanmogne, 2002, Journal of neuropathology and experimental neurology.

Pigment epithelium-derived factor (PEDF) protects cortical neurons in vitro from oxidant injury by activation of extracellular signal-regulated kinase (ERK) 1/2 and induction of Bcl-2

P. Grammas, D. Tripathy, Jinhua Luo, 2012, Neuroscience Research.

Review Article Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

A. Fagan, M. Weiner, T. Montine, 2014 .

Blocking L-type calcium channels reduced the threshold of cAMP-induced steroidogenic acute regulatory gene expression in MA-10 mouse Leydig cells.

A. Pandey, P. Grammas, D. Stocco, 2010, The Journal of endocrinology.

Expression of CAP37, a novel inflammatory mediator, in Alzheimer's disease

P. Grammas, Padmasini Kumar, H. Pereira, 1996, Neurobiology of Aging.

Angiogenesis in rat aorta ring explant cultures.

P. Grammas, C. Diglio, F. Giacomelli, 1989, Laboratory investigation; a journal of technical methods and pathology.

Cholinergic‐Adrenergic Receptor Interactions in Cerebral Microvessels

P. Grammas, C. Diglio, F. Giacomelli, 1985, Journal of neurochemistry.

Mechanisms of cell death in primary cortical neurons and PC12 cells

P. Weigel, P. Grammas, U. Reimann‐Philipp, 2001, Journal of neuroscience research.

Chronic thrombin exposure results in an increase in apolipoprotein‐E levels

K. Hensley, P. Grammas, Albert Nguyen, 2006, Journal of neuroscience research.

IL-8 induces expression of matrix metalloproteinases, cell cycle and pro-apoptotic proteins, and cell death in cultured neurons.

L. Yin, P. Grammas, L. Thirumangalakudi, 2007, Journal of Alzheimer's disease : JAD.

Cerebrovascular Angiotensin II Receptors in Spontaneously Hypertensive Rats

P. Grammas, C. Diglio, F. Giacomelli, 1989, Journal of cardiovascular pharmacology.

Production of Neurotoxic Factors by Brain Endothelium in Alzheimer's Disease a

P. Weigel, P. Grammas, P. Moore, 1997, Annals of the New York Academy of Sciences.

Regulation of amino acid uptake into cerebral microvessels

P. Grammas, M. Caspers, T. Kwaiser, 1992, Neuropharmacology.

Angiotensin II and atrial natriuretic factor receptor interactions at the blood-brain barrier

P. Grammas, D. Bessert, F. Giacomelli, 1991, Brain Research.

Sunitinib enhances neuronal survival in vitro via NF-κB-mediated signaling and expression of cyclooxygenase-2 and inducible nitric oxide synthase

P. Grammas, D. Tripathy, Alma C Sanchez, 2013, Journal of Neuroinflammation.

Transcriptional regulation of calcium-activated neutral protease in cardiomyocytes of hypertensive rats.

P. Grammas, F. Giacomelli, J. Wiener, 1992, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

Anoxic injury of endothelial cells increases production of nitric oxide and hydroxyl radicals.

R. Floyd, P. Grammas, G. Liu, 1996, Biochemical and biophysical research communications.

Pathological changes in Alzheimer’s brain evaluated with fluorescence emission analysis (FEA)

Alexander Christov, Todd Ottman, Paula Grammas, 2004, SPIE BiOS.

Acetaminophen inhibits neuronal inflammation and protects neurons from oxidative stress

P. Grammas, D. Tripathy, Debjani Tripathy, 2009, Journal of Neuroinflammation.

Acetaminophen inhibits neuronal inflammation and protects neurons from oxidative stress

P. Grammas, D. Tripathy, Debjani Tripathy, 2009 .

MIP1‐α expression is elevated in Alzheimer's vessels and is regulated by oxidative and lipid stress

P. Grammas, L. Thirumangalakudi, Debjani Tripathy, 2007 .

The vasculature in Alzheimer\'s disease: a new therapeutic target for an old disease?

P. Grammas, 2011 .

Short Communication Microvessels from Alzheimer’s Disease Brains Kill Neurons in Vitro

P. Weigel, P. Grammas, P. Moore, 1999 .

Involvement of PGE2 and PGDH but not COX-2 in thrombin-induced cortical neuron apoptosis

P. Grammas, L. Thirumangalakudi, H. Rao, 2009, Neuroscience Letters.

CAP37, a Novel Inflammatory Mediator Its Expression in Endothelial Cells and Localization to Atherosclerotic Lesions

P. Grammas, Padmasini Kumar, Taunia D. Lee, 2002 .

Inhibition of thromboxane a synthase activity enhances steroidogenesis and steroidogenic acute regulatory gene expression in MA-10 mouse Leydig cells.

R. Schiffer, P. Grammas, S. King, 2008, Endocrinology.

The involvement of epoxygenase metabolites of arachidonic acid in cAMP-stimulated steroidogenesis and steroidogenic acute regulatory protein gene expression.

R. Schiffer, Chwan-Li Shen, P. Grammas, 2006, The Journal of endocrinology.