I. Sanz

发表

Tumor Necrosis Factor Alpha Receptor I Is Important for Survival from Streptococcus pneumoniaeInfections

D. O'Brien, D. Briles, A. Szalai, 1999, Infection and Immunity.

, Infections pneumoniae Streptococcus Important for Survival from Tumor Necrosis Factor Alpha Receptor I Is

D. O'Brien, D. Briles, A. Szalai, 1999 .

Elucidation of seventeen human peripheral blood B‐cell subsets and quantification of the tetanus response using a density‐based method for the automated identification of cell populations in multidimensional flow cytometry data

R. Scheuermann, Jennifer Cai, John Campbell, 2010, Cytometry. Part B, Clinical cytometry.

AID expression in peripheral blood of children living in a malaria holoendemic region is associated with changes in B cell subsets and Epstein‐Barr virus

I. Sanz, J. Wilmore, Chungwen Wei, 2015, International journal of cancer.

Reconstitution of the adult B cell repertoire after treatment with rituximab

I. Sanz, J. Anolik, 2005, Arthritis research & therapy.

B cell reconstitution after rituximab treatment of lymphoma recapitulates B cell ontogeny.

J. Friedberg, R. Fisher, E. Milner, 2007, Clinical immunology.

Novel Human Transitional B Cell Populations Revealed by B Cell Depletion Therapy1

I. Sanz, J. Anolik, R. Looney, 2009, The Journal of Immunology.

Long-Lived Plasma Cells Are Contained within the CD19(-)CD38(hi)CD138(+) Subset in Human Bone Marrow.

Hao Wu, Iñaki Sanz, Ann R. Falsey, 2015, Immunity.

BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data

Iñaki Sanz, Bali Pulendran, Robert C. Kauffman, 2018, Genome Medicine.

Anergic Responses Characterize a Large Fraction of Human Autoreactive Naive B Cells Expressing Low Levels of Surface IgM

Hongmei Yang, E. Milner, I. Sanz, 2011, The Journal of Immunology.

Epigenetic programming underpins B cell dysfunction in human SLE

Christopher D. Scharer, B. Barwick, I. Sanz, 2019, Nature Immunology.

B cells as therapeutic targets in SLE

I. Sanz, F. E. Lee, F. Lee, 2010, Nature Reviews Rheumatology.

Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.

A. Cappione, A. Pugh-Bernard, G. Silverman, 2005, The Journal of clinical investigation.

Dysregulation of germinal centres in autoimmune disease

M. Cook, C. Vinuesa, I. Sanz, 2009, Nature Reviews Immunology.

NF-κB Regulates VCAM-1 Expression on Fibroblast-Like Synoviocytes1

E. Schwarz, R. O’Keefe, Ping Li, 2000, The Journal of Immunology.

Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus.

A. Cappione, A. Pugh-Bernard, I. Sanz, 2004, Arthritis and rheumatism.

B lymphocytes in systemic lupus erythematosus: lessons from therapy targeting B cells

I. Sanz, J. Anolik, I. Sanz, 2004, Lupus.

B cells as therapeutic targets for rheumatic diseases

I. Sanz, J. Anolik, R. Looney, 2004, Current opinion in rheumatology.

Tumor necrosis factor alpha receptor I is important for survival from Streptococcus pneumoniae infections.

D. O'Brien, D. Briles, A. Szalai, 1999, Infection and immunity.

From Cold-Agglutinin Disease to Systemic Lupus Erythematosus: Lessons in Human B-Cell Tolerance and Its Breakdown

A. Cappione, A. Pugh-Bernard, I. Sanz, 2004, Transfusion Medicine and Hemotherapy.

Human innate B cells: a link between host defense and autoimmunity?

E. Milner, A. Cappione, I. Sanz, 2005, Springer Seminars in Immunopathology.

Breach and Restoration of B-cell Tolerance in Human Systemic Lupus Erythematosus (SLE)

I. Sanz, J. Anolik, R. Looney, 2008 .

New therapies for systemic lupus erythematosus: cellular targets.

I. Sanz, J. Anolik, R. Looney, 2006, Rheumatic diseases clinics of North America.

A New Population of Cells Lacking Expression of CD27 Represents a Notable Component of the B Cell Memory Compartment in Systemic Lupus Erythematosus1

E. Milner, A. Cappione, A. Pugh-Bernard, 2007, The Journal of Immunology.

GLaMST: grow lineages along minimum spanning tree for b cell receptor sequencing data

Enlu Zhou, P. Qiu, I. Sanz, 2020, BMC genomics.

Polychromatic flow cytometry in evaluating rheumatic disease patients

I. Sanz, Chungwen Wei, Scott A Jenks, 2015, Arthritis Research & Therapy.

Surface of Human B Lymphocytes 220-kDa Glycoform of CD45/B220 on the Lupus IgG VH4.34 Antibodies Bind to a

A. Cappione, A. Pugh-Bernard, I. Sanz, 2013 .

Lupus IgG VH4.34 Antibodies Bind to a 220-kDa Glycoform of CD45/B220 on the Surface of Human B Lymphocytes1

A. Cappione, A. Pugh-Bernard, I. Sanz, 2004, The Journal of Immunology.

B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I/II dose-escalation trial of rituximab.

I. Sanz, J. Anolik, J. Sloand, 2004, Arthritis and rheumatism.

Selected Topics in Systemic Lupus Erythematosus: B Cells in Lupus and Lupus Nephritis

I. Sanz, S. Lim, S. S. Lim, 2013 .

Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion

G. Gibson, Ronghu Wu, I. Sanz, 2018, Nature Communications.

Differential transcriptome and development of human peripheral plasma cell subsets.

R. Scheuermann, G. Gibson, Y. Qian, 2019, JCI insight.

Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies

Ahnalee M. Brincks, J. M. Crawford, Stefani N. Thomas, 2022, Open forum infectious diseases.

A perspective on B-cell-targeting therapy for SLE

I. Sanz, J. Anolik, R. John Looney, 2010, Modern rheumatology.

B-cell-depleting Therapy in Systemic Lupus

J. Stone, M. Khamashta, I. Sanz, 2012 .

B-cell-depleting therapy in systemic lupus erythematosus.

J. Stone, M. Khamashta, I. Sanz, 2012, The American journal of medicine.

Erythematosus Compartment in Systemic Lupus Component of the B Cell Memory Expression of CD 27 Represents a Notable A New Population of Cells Lacking

E. Milner, A. Cappione, A. Pugh-Bernard, 2007 .

Factors Affecting Early Antibody Secreting Cell Maturation Into Long-Lived Plasma Cells

I. Sanz, C. Joyner, I. Sanz, 2019, Front. Immunol..

B cells and immunological tolerance.

I. Sanz, Nataly Manjarrez-Orduño, T. Quach, 2009, The Journal of investigative dermatology.

B cell depletion therapy in systemic lupus erythematosus

I. Sanz, J. Anolik, R. Looney, 2003, Current rheumatology reports.

Expansion of Activated Peripheral Blood Memory B Cells in Rheumatoid Arthritis, Impact of B Cell Depletion Therapy, and Biomarkers of Response

I. Sanz, J. Anolik, R. Looney, 2015, PloS one.

Phenotypic and functional heterogeneity of human memory B cells.

I. Sanz, J. Anolik, F. E. Lee, 2008, Seminars in immunology.

B cell therapies for rheumatoid arthritis: beyond B cell depletion.

I. Sanz, J. Nieto, I. Calero, 2010, Rheumatic diseases clinics of North America.

Dendritic Cell Networks Lymphoid Germinal Centers and Follicular Memory B Lymphocytes via Effects on Therapy in Rheumatoid Arthritis Inhibits Cutting Edge : Anti-Tumor Necrosis Factor

A. Almudevar, E. Milner, I. Sanz, 2007 .

Follicular lymphoma tumor-infiltrating T-helper (T(H)) cells have the same polyfunctional potential as normal nodal T(H) cells despite skewed differentiation.

O. Hyrien, W. R. Burack, I. Sanz, 2011, Blood.

Elevated SARS-CoV-2 Antibodies Distinguish Severe Disease in Early COVID-19 Infection

Hao Wu, Monica Cabrera-Mora, I. Sanz, 2020, bioRxiv.

Fibroblast-Like Synoviocytes B Regulates VCAM-1 Expression on κ NF -

R. O’Keefe, I. Sanz, S. Li, 2000 .

Down‐regulation of CD20 on B cells upon CD40 activation

A. Bottaro, I. Sanz, J. Anolik, 2003, European journal of immunology.

Circulating Human Antibody-Secreting Cells during Vaccinations and Respiratory Viral Infections Are Characterized by High Specificity and Lack of Bystander Effect

E. Walsh, A. Falsey, I. Sanz, 2011, The Journal of Immunology.

Polymorphisms of Immunologically Relevant Loci in Human Disease

J. D. Capra, I. Sanz, R. Wasserman, 1988, Annals of the New York Academy of Sciences.

A structural basis for human cross-reacting idiotypes.

J. D. Capra, I. Sanz, R. Makar, 1988, Annales de l'Institut Pasteur. Immunology.

Neutrophil-Mediated IFN Activation in the Bone Marrow Alters B Cell Development in Human and Murine Systemic Lupus Erythematosus

J. Liesveld, J. Knight, E. Baechler, 2014, The Journal of Immunology.

Treatment of SLE with anti-CD20 monoclonal antibody.

I. Sanz, J. Anolik, R. Looney, 2005, Current directions in autoimmunity.

B cell depletion therapy in autoimmune diseases.

I. Sanz, J. Anolik, R. Looney, 2007, Frontiers in bioscience : a journal and virtual library.

Polymorphism in Vk10 genes encoding L chains of antibodies bearing the Ars-A and A48 cross-reactive idiotypes

J. D. Capra, P. Gottlieb, I. Sanz, 2004, Immunogenetics.

CD23+CD21highCD1dhigh B Cells in Inflamed Lymph Nodes Are a Locally Differentiated Population with Increased Antigen Capture and Activation Potential

E. Schwarz, A. Bottaro, I. Sanz, 2012, The Journal of Immunology.

CD23CD21CD1d B Cells in Inflamed Lymph Nodes Are a Locally Differentiated Population with Increased Antigen Capture and Activation Potential

E. Schwarz, I. Sanz, S. Moshkani, 2012 .

Antigen Capture and Activation Potential Differentiated Population with Increased Inflamed Lymph Nodes Are a Locally B Cells inhighCD 1 dhighCD 21 + CD 23

E. Schwarz, A. Bottaro, I. Sanz, 2012 .

Rationale for B cell targeting in SLE

I. Sanz, 2014, Seminars in Immunopathology.

Connective tissue diseases: Targeting B cells in SLE: good news at last!

I. Sanz, 2011, Nature Reviews Rheumatology.

Novel Human Transitional B Cell Populations

I. Sanz, J. Anolik, R. Looney, 2009 .

Expanded CD23+/CD21hi B Cells in Inflamed Lymph Nodes Are Associated with the Onset of Inflammatory-Erosive Arthritis in TNF-Transgenic Mice and Are Targets of Anti-CD20 Therapy

J. Li, E. Schwarz, A. Bottaro, 2010, The Journal of Immunology.

Anti-CD20 Therapy in TNF-Transgenic Mice and Are Targets of the Onset of Inflammatory-Erosive Arthritis Inflamed Lymph Nodes Are Associated with B Cells in hi /CD21+ Expanded CD23

E. Schwarz, A. Bottaro, L. Xing, 2010 .

B cells in human and murine systemic lupus erythematosus

I. Sanz, J. Anolik, 2004, Current opinion in rheumatology.

Response Using Phage-Display Combinatorial Erythematosus Anti-Smith Antibody Delineation of the Human Systemic Lupus

J. Harley, I. Sanz, J. James, 2000 .

Empirical advantages of adeno associated viral vectors in vivo gene therapy for arthritis.

G. Kollias, E. Schwarz, G. Firestein, 2000, The Journal of rheumatology.

Cutting Edge: Anti-Tumor Necrosis Factor Therapy in Rheumatoid Arthritis Inhibits Memory B Lymphocytes via Effects on Lymphoid Germinal Centers and Follicular Dendritic Cell Networks1

A. Almudevar, E. Milner, I. Sanz, 2008, The Journal of Immunology.

Indications of rituximab in autoimmune diseases.

I. Sanz, 2009, Drug discovery today. Therapeutic strategies.

Targeting B cells for the treatment of SLE: the beginning of the end or the end of the beginning?

I. Sanz, I. Calero, 2010, Discovery medicine.

The relationship of FcgammaRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus.

I. Sanz, J. Anolik, R. Looney, 2003, Arthritis and rheumatism.

Circulating antibody-secreting cells during acute respiratory syncytial virus infection in adults.

E. Walsh, A. Falsey, I. Sanz, 2010, The Journal of infectious diseases.

Extrafollicular IgD+ B cells generate IgE antibody secreting cells in the nasal mucosa

G. Gibson, Hao Wu, K. Magliocca, 2021, Mucosal Immunology.

Ablation of tumor necrosis factor receptor type I (p55) alters oxygen-induced lung injury.

G. Pryhuber, D. O'Brien, I. Sanz, 2000, American journal of physiology. Lung cellular and molecular physiology.

Small Human VH Gene Families Show Remarkably Little Polymorphism

J. D. Capra, I. Sanz, L. Weigel, 1991 .

Nucleotide sequences of eight human natural autoantibody VH regions reveals apparent restricted use of VH families.

J. D. Capra, P. Casali, I. Sanz, 1989, Journal of immunology.

This information is current as Cells Expressing Low Levels of Surface IgM Fraction of Human Autoreactive Naive B Anergic Responses Characterize a Large

Hongmei Yang, I. Sanz, Éric, 2011 .

Ro/SS-A and the pathogenic significance of its antibodies.

J. D. Capra, M. Siciliano, I. Sanz, 1989, Journal of autoimmunity.

OMIP‐003: Phenotypic analysis of human memory B cells

I. Sanz, Chungwen Wei, J. Jung, 2011, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

In vivo cell penetration and intracellular transport of anti-Sm and anti-La autoantibodies.

I. Sanz, S. Deng, E. Hanson, 2000, International immunology.

Characterization of human anti-acetylcholine receptor monoclonal autoantibodies from the peripheral blood of a myasthenia gravis patient using combinatorial libraries.

I. Sanz, M. Fischbach, K. Krolick, 2000, Clinical immunology.

Rationale for B cell targeting in SLE

I. Sanz, 2014, Seminars in Immunopathology.

The genetic origin of human autoantibodies.

I. Sanz, J. Capra, 1988, Journal of immunology.

Molecular characterization of human Ig heavy chain DIR genes.

I. Sanz, M. Fischbach, S. Wang, 1994, Journal of immunology.

Systemic lupus erythematosus: Extent and patterns of off-label use of rituximab for SLE

I. Sanz, 2016, Nature Reviews Rheumatology.

VH sequence of a human anti-Sm autoantibody. Evidence that autoantibodies can be unmutated copies of germline genes.

M. Takei, I. Sanz, N. Talal, 1989, Journal of immunology.

Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen.

Itoh, M. Siciliano, I. Sanz, 1990, The Journal of clinical investigation.

Updates on B-cell immunotherapies for systemic lupus erythematosus and Sjogren's syndrome

I. Sanz, A. Coca, 2012, Current opinion in rheumatology.

Understanding and measuring human B‐cell tolerance and its breakdown in autoimmune disease

Christopher D. Scharer, I. Sanz, F. Eun-Hyung Lee, 2019, Immunological reviews.

The smaller human VH gene families display remarkably little polymorphism.

I. Sanz, P. Tucker, C. Williams, 1989, The EMBO journal.

Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions.

I. Sanz, Ignacio Sanz, 1991, Journal of immunology.

Human Ig heavy chain CDR3 regions in adult bone marrow pre-B cells display an adult phenotype of diversity: evidence for structural selection of DH amino acid sequences.

I. Sanz, C. Raman, M. Fischbach, 1997, International immunology.

The molecular genetics of the arsonate idiotypic system of A/J mice.

I. Sanz, P. Tucker, K. Meek, 1988, Advances in immunology.

Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function

Peter D. Crompton, O. Doumbo, J. Skinner, 2015, eLife.

Diversity, cellular origin and autoreactivity of antibody-secreting cell expansions in acute Systemic Lupus Erythematosus

Ivan V. Gregoretti, I. Sanz, W. Cheung, 2015, Nature Immunology.

Effect of long-term belimumab treatment on B cells in systemic lupus erythematosus: extension of a phase II, double-blind, placebo-controlled, dose-ranging study.

B. Diamond, I. Sanz, A. Jacobi, 2010, Arthritis and rheumatism.

Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy.

I. Sanz, J. Anolik, R. Looney, 2007, Arthritis and rheumatism.

The TLR9 Ligand CpG Promotes the Acquisition of Plasmodium falciparum-Specific Memory B Cells in Malaria-Naive Individuals1

Peter D. Crompton, J. Treanor, I. Sanz, 2009, The Journal of Immunology.

Connective tissue diseases: The conundrum of B cell depletion in SLE

I. Sanz, 2009, Nature Reviews Rheumatology.

Insights into the heterogeneity of human B cells: diverse functions, roles in autoimmunity, and use as therapeutic targets

I. Sanz, T. Randall, J. Anolik, 2009, Immunologic research.

Individuals-Specific Memory B Cells in Malaria-Naive Plasmodium falciparum Acquisition of The TLR 9 Ligand CpG Promotes the Martin and

Peter D. Crompton, J. Treanor, I. Sanz, 2009 .

New Perspectives in Rheumatology: May You Live in Interesting Times: Challenges and Opportunities in Lupus Research

I. Sanz, 2017, Arthritis & rheumatology.

Understanding B‐cell activation and autoantibody repertoire selection in systemic lupus erythematosus: A B‐cell immunomics approach

I. Sanz, Alexander F. Rosenberg, Christopher Fucile, 2018, Immunological reviews.

Altered B cell receptor signaling in human systemic lupus erythematosus.

I. Sanz, S. Jenks, 2009, Autoimmunity reviews.

Syk inhibition with fostamatinib leads to transitional B lymphocyte depletion.

J. Friedberg, I. Sanz, Chungwen Wei, 2012, Clinical immunology.

V kappa and J kappa gene segments of A/J Ars-A antibodies: somatic recombination generates the essential arginine at the junction of the variable and joining regions.

I. Sanz, J. Capra, 1987, Proceedings of the National Academy of Sciences of the United States of America.

The relationship of FcγRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus

I. Sanz, J. Anolik, R. Looney, 2003 .

Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity

M. Tekin, V. D’Agati, F. Quintana, 2016, Cell.

Generation of human long-lived plasma cells by developmentally regulated epigenetic imprinting

S. Lonial, Christopher D. Scharer, I. Sanz, 2021, Life Science Alliance.

Comparison of D, JH, and junctional diversity in the fetal, adult, and aged B cell repertoires.

I. Sanz, J. Teale, L. Bangs, 1991, Journal of immunology.

Primary Sjögren's Syndrome Is Characterized by Distinct Phenotypic and Transcriptional Profiles of IgD+ Unswitched Memory B Cells

M. Iadarola, I. Sanz, J. Anolik, 2014, Arthritis & rheumatology.

Delineation of the Human Systemic Lupus Erythematosus Anti-Smith Antibody Response Using Phage-Display Combinatorial Libraries1

J. Harley, I. Sanz, J. James, 2000, The Journal of Immunology.

Cloning of a human IgM autoantibody bearing a cross-reactive idiotype in a lambda expression vector: a new approach to studying autoantibodies.

I. Sanz, N. Talal, M. Fischbach, 1993, Clinical immunology and immunopathology.

Immunologic Memory: B cells

I. Sanz, F. E. Lee, F. Lee, 2012 .

Affinity maturation generates pathogenic antibodies with dual reactivity to DNase1L3 and dsDNA in systemic lupus erythematosus

M. Petri, I. Sanz, Jessica Li, 2023, Nature Communications.

A molecular and structural analysis of the VH and VK regions of monoclonal antibodies bearing the A48 regulatory idiotype.

C. Bona, F. Bonilla, I. Sanz, 1990, Journal of Immunology.

Regulation of T and B cell responses to chronic antigenic stimulation during Infection, autoimmunity and transplantation

R. Ahmed, I. Sanz, M. Ford, 2019, Immunological reviews.

Structure and specificities of anti-ganglioside autoantibodies associated with motor neuropathies.

B. Patten, N. Weng, I. Sanz, 1992, Journal of immunology.

DNA methylation changes on immune cells in Systemic Lupus Erythematosus

I. Sanz, G. Vásquez, Scott A Jenks, 2020, Autoimmunity.

Maturation of Human Long-lived Plasma Cells Results in Resistance to Apoptosis by Transcriptional and Epigenetic Regulation

G. Gibson, S. Lonial, Christopher D. Scharer, 2021, bioRxiv.

BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data

B. Pulendran, J. Wrammert, S. Crotty, 2018, Genome Medicine.

GLaMST: grow lineages along minimum spanning tree for b cell receptor sequencing data

Peng Qiu, Iñaki Sanz, Enlu Zhou, 2018, BMC Genomics.

Broadly cross-reactive HIV neutralizing human monoclonal antibody Fab selected by sequential antigen panning of a phage display library.

S. Rybak, C. Broder, D. Dimitrov, 2003, Journal of immunological methods.

NF-kappa B regulates VCAM-1 expression on fibroblast-like synoviocytes.

E. Schwarz, R. O’Keefe, I. Sanz, 2000, Journal of immunology.

ImmPort FLOCK: Automated cell population identification in high dimensional flow cytometry data (42.17)

Yu Qian, Richard H. Scheuermann, Iñaki Sanz, 2009, The Journal of Immunology.

Cloning of size-selected human immunoglobulin heavy-chain rearrangements from third complementarity-determining region fingerprint profiles.

I. Sanz, F. Raaphorst, J. Tami, 1996, BioTechniques.

This information is current as Erythematosus Human and Murine Systemic Lupus Bone Marrow Alters B Cell Development in Neutrophil-Mediated IFN Activation in the

J. Liesveld, J. Knight, E. Baechler, 2013 .

Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance.

A. Cappione, A. Pugh-Bernard, G. Silverman, 2001, The Journal of clinical investigation.

Author Correction: Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion

G. Gibson, Ronghu Wu, I. Sanz, 2019, Nature Communications.

Nitin J. Karandikar, R. Scheuermann, Jennifer Cai, 2010, Cytometry. Part B, Clinical cytometry.

OMIP‐003: Phenotypic analysis of human memory B cells

I. Sanz, Chungwen Wei, John Jung, 2011, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

New Perspectives in Rheumatology: May You Live in Interesting Times: Challenges and Opportunities in Lupus Research

I. Sanz, 2017, Arthritis & rheumatology.

Long-Lived Plasma Cells Are Contained within the CD19(-)CD38(hi)CD138(+) Subset in Human Bone Marrow.

Ivan V. Gregoretti, E. Walsh, A. Falsey, 2015, Immunity.