H. Bluethmann

R. Pauwels, J. Tavernier, H. Bluethmann, 1994, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Analysis of the immune system with transgenic mice: T cell development

H. Bluethmann, 1991, Experientia.

Functional expression of a human TCR/3 gene in transgenic mice

S. Ryser, U. Mueller, H. Bluethmann, 2005 .

Signaling molecules and neuroglial activation in the injured central nervous system.

G. Kreutzberg, H. Bluethmann, G. Raivich, 1996, The Keio journal of medicine.

Greatly accelerated lymphadenopathy and autoimmune disease in lpr mice lacking tumor necrosis factor receptor I.

Z. Wang, Pingar Yang, J. Mountz, 1996, Journal of immunology.

Origin of CD4-CD8-B220+ T cells in MRL-lpr/lpr mice. Clues from a T cell receptor beta transgenic mouse.

J. Mountz, H. Bluethmann, T. Zhou, 1993, Journal of immunology.

T helper 2 cells are subject to high dose oral tolerance and are not essential for its induction.

E. Worthey, F. Liew, H. Bluethmann, 1995, Journal of immunology.

Tumor necrosis factor (TNF)-induced cutaneous necrosis is mediated by TNF receptor 1.

H. Bluethmann, N. Schultze, P. Koebel, 1995, Journal of inflammation.

Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4.

M. Marinaro, J. Mcghee, H. Kiyono, 1995, Journal of immunology.

Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice.

R. Pauwels, G. Joos, H. Bluethmann, 1995, American journal of respiratory cell and molecular biology.

Immune responses in Interleukin 4-deficient mice

R. Pauwels, H. Bluethmann, G. Köhler, 1994 .

T cell influence on superantigen-induced arthritis in MRL-lpr/lpr mice.

J. Mountz, C. Edwards, H. Bluethmann, 1994, Arthritis and rheumatism.

Apoptosis defects analyzed in TcR transgenic and fas transgenic lpr mice.

J. Mountz, C. Edwards, H. Bluethmann, 1994, International reviews of immunology.

muscles in parvalbumin knockout mice Prolonged contraction-relaxation cycle of fast-twitch

J. Eilers, G. Vrbóva, Christian D. Wilms, 2010 .

Interleukin‐6 (IL6) and cellular response to facial nerve injury: effects on lymphocyte recruitment, early microglial activation and axonal outgrowth in IL6‐deficient mice

L. Jones, H. Bluethmann, G. Raivich, 2001, The European journal of neuroscience.

B7.2 on activated and phagocytic microglia in the facial axotomy model: regulation by interleukin-1 receptor type 1, tumor necrosis factor receptors 1 and 2 and endotoxin

K. Pfeffer, H. Bluethmann, G. Raivich, 2004, Journal of Neuroimmunology.

Defective clonal deletion and anergy induction in TCR transgenic lpr/lpr mice.

J. Mountz, H. Bluethmann, T. Zhou, 1994, Seminars in immunology.

Interleukin-4-de¢cient BALB/c mice develop an enhanced Th1-like response but control cardiac in£ammation following Borrelia burgdorferi infection

S. Telford, A. Satoskar, H. Bluethmann, 2000 .

The helper T-cell repertoire of mice expressing class II major histocompatibility complex β chains in the absence of α chains

J. Guenot, H. Bluethmann, Z. Nagy, 1997, Immunogenetics.

Developmental Biology of T Lymphocytes

H. Bluethmann, H. von Boehmer, P. Kisielow, 1988, Annual review of immunology.

Major histocompatibility complex (MHC2+) perivascular macrophages in the axotomized facial motor nucleus are regulated by receptors for interferon-γ (IFNγ) and tumor necrosis factor (TNF)

K. Pfeffer, H. Bluethmann, G. Raivich, 2005, Neuroscience.

Apoptosis-inducing members of the tumor necrosis factor supergene family: Potential functions in placentae

H. Bluethmann, J. S. Hunt, C. Rasmussen, 1999 .

The developmental biology of T lymphocytes.

H. Bluethmann, H. von Boehmer, P. Kisielow, 1988, Annual review of immunology.

Mutations affecting either generation or survival of cells influence the pool size of mature B cells.

A. Rolink, F. Melchers, H. Bluethmann, 1999, Immunity.

Ligand- Expressing Antigen-Presenting Cells Induction of Specific T Cell Tolerance by Fas

H. Bluethmann, Z. Wang, T. Zhou, 2013 .

Induction of specific T cell tolerance by Fas ligand-expressing antigen-presenting cells.

Pingar Yang, J. Mountz, W. Liu, 1999, Journal of immunology.

Enterotoxin adjuvants have direct effects on T cells and antigen-presenting cells that result in either interleukin-4-dependent or -independent immune responses.

Y. Takeda, J. Mcghee, H. Kiyono, 2000, The Journal of infectious diseases.

Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice.

R. Zinkernagel, B. Ryffel, M. Le Hir, 1996, International immunology.

Tumor necrosis factor receptor-1 signaling is required for differentiation of follicular dendritic cells, germinal center formation, and full antibody responses.

B. Ryffel, M. Le Hir, F. D. Di Padova, 1995, Journal of inflammation.

CRITICAL ROLE OF TNF-RECEPTOR 1 BUT NOT 2 IN HEPATIC STELLATE CELL-INDUCED EXTRACELLULAR MATRIX REMODELING AND IN VIVO LIVER FIBROSIS

A. Moles, H. Bluethmann, M. Marí, 2010 .

T Cell Tolerance in T Cell Receptor Transgenic lpr/lpr Mice

J. Mountz, H. Bluethmann, T. Zhou, 1994 .

The gamma 2 subunit of GABA(A) receptors is required for maintenance of receptors at mature synapses.

I. Mansuy, H. Bluethmann, C. Schweizer, 2003, Molecular and cellular neurosciences.

MHC-II-Independent CD4+ T Cells Induce Colitis in Immunodeficient RAG−/− Hosts1

H. Macdonald, P. Möller, H. Bluethmann, 2001, The Journal of Immunology.

T Cells Induce Colitis in Immunodeficient RAG Hosts

H. Macdonald, H. Bluethmann, F. Leithäuser, 2001 .

Impaired Platelet Activation in Familial High Density Lipoprotein Deficiency (Tangier Disease)*

G. Assmann, U. Seedorf, J. Nofer, 2004, Journal of Biological Chemistry.

Inhibition of superantigen-induced proinflammatory cytokine production and inflammatory arthritis in MRL-lpr/lpr mice by a transcriptional inhibitor of TNF-alpha.

J. Mountz, C. Edwards, H. Bluethmann, 1996, Journal of immunology.

Oral immunization of interleukin-4 (IL-4) knockout mice with a recombinant Salmonella strain or cholera toxin reveals that CD4+ Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses

J. Mcghee, H. Kiyono, M. Yamamoto, 1996, Infection and immunity.

The Role of Th1 and Th2 Cells for Mucosal IgA Responses a

M. Marinaro, J. Mcghee, H. Kiyono, 1996, Annals of the New York Academy of Sciences.

Cutting Edge: Modulation of Intestinal Autoimmunity and IL-2 Signaling by Sphingosine Kinase 2 Independent of Sphingosine 1-Phosphate1

E. Samy, S. Peng, H. Bluethmann, 2007, The Journal of Immunology.

Sphingosine 1-Phosphate Sphingosine Kinase 2 Independent of Autoimmunity and IL-2 Signaling by Cutting Edge: Modulation of Intestinal

E. Samy, H. Bluethmann, J. Lora, 2007 .

Liver and brain metallothionein regulation in transgenic mice overexpressing interleukin-6 and in mice carrying a null mutation in the interleukin-6 gene

B. González, H. Bluethmann, I. Campbell, 1999 .

Impaired immune and acute-phase responses in interleukin-6-deficient mice

R. Zinkernagel, H. Baumann, T. Kishimoto, 1994, Nature.

Deletion of CD4+ T cells and thymocytes by apoptosis in mouse mammary tumor virus (C4)‐infected Vβ2 transgenic mice

Hong Wang, W. Wei, H. Bluethmann, 1994, European journal of immunology.

Requirement for Tumor Necrosis Factor Receptor 2 Expression on Vascular Cells To Induce Experimental Cerebral Malaria

D. Männel, G. Grau, H. Bluethmann, 2002, Infection and Immunity.

Abnormal thymocyte development and production of autoreactive T cells in T cell receptor transgenic autoimmune mice.

J. Mountz, H. Bluethmann, M. Brockhaus, 1991, Journal of immunology.

Postsynaptic clustering of γ-aminobutyric acid type A receptors by the γ3 subunit in vivo

J. Benson, H. Bluethmann, J. Fritschy, 1999 .

Allelic exclusion at DNA rearrangement level is required to prevent coexpression of two distinct T cell receptor beta genes

H. Bluethmann, M. Steinmetz, J. V. van Meerwijk, 1991, The Journal of experimental medicine.

The lectin‐like domain of tumor necrosis factor‐α increases membrane conductance in microvascular endothelial cells and peritoneal macrophages

P. De Baetselier, F. G. van der Goot, L. Fransen, 1999, European journal of immunology.

Development and function of autospecific dual TCR+ T lymphocytes.

H. Bluethmann, P. Tseng, T. Finkel, 1999, International immunology.

Transgenesis and targeted mutagenesis in immunology.

P. Ohashi, H. Bluethmann, 1994 .

Disruption of the murine IL-4 gene blocks Th2 cytokine responses

Martin Bachmann, Graham Le Gros, M. Bachmann, 1993, Nature.

control of Leishmania donovani infection. mexicana infection but does not increase Leishmania inhibits disease progression during Disruption of the murine interleukin-4 gene

A. Satoskar, H. Bluethmann, J. Alexander, 2013 .

Disruption of the murine interleukin-4 gene inhibits disease progression during Leishmania mexicana infection but does not increase control of Leishmania donovani infection

A. Satoskar, H. Bluethmann, J. Alexander, 1995, Infection and immunity.

Multivalent structure of an ab T cell receptor

Mar Alvarez, B. Alarcón, H. Bluethmann, 1999 .

Multivalent structure of an alphabetaT cell receptor.

B. Alarcón, H. Bluethmann, A. De La Hera, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon gamma and tumor necrosis factor alpha

S. Kaufmann, I. Flesch, S. Huang, 1995, The Journal of experimental medicine.

Immune response in mice that lack the interferon-gamma receptor.

R. Zinkernagel, J. Vilček, S. Huang, 1993, Science.

Endogenous Tumor Necrosis Factor α (TNFα) Requires TNF Receptor Type 2 to Generate Heat Hyperalgesia in a Mouse Cancer Model

H. Bluethmann, Zhen-Zhong Xu, R. Ji, 2008, The Journal of Neuroscience.

Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors.

A. Aguzzi, J. Benson, H. Bluethmann, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Benzodiazepine actions mediated by specific γ-aminobutyric acidA receptor subtypes

J. Benson, H. Bluethmann, J. Fritschy, 1999, Nature.

Stress-induced enhancement of skin immune function: A role for γ interferon

F. Dhabhar, B. McEwen, A. Satoskar, 2000 .

A crucial role for B cells in neuroinvasive scrapie

A. Aguzzi, R. Zinkernagel, A. Raeber, 1997, Nature.

Obligatory Requirement for Antibody in Recovery from a Primary Poxvirus Infection

G. Karupiah, H. Bluethmann, G. Chaudhri, 2006, Journal of Virology.

The 55-kD Tumor Necrosis Factor Receptor and CD95 Independently Signal Murine Hepatocyte Apoptosis and Subsequent Liver Failure

M. Leist, A. Wendel, G. Tiegs, 1996, Molecular medicine.

Targeted disruption of the MHC class II Aa gene in C57BL/6 mice.

H. Bluethmann, M. Steinmetz, Frank Koentgen, 1993, International immunology.

Antiviral Activity of Tumor Necrosis Factor (TNF) Is Mediated via p55 and p75 TNF Receptors

J. Peschon, H. Bluethmann, J. Ruby, 1997, The Journal of experimental medicine.

Physiological, Immunological, and Pathological Functions of Tumor Necrosis Factor (TNF) Revealed by TNF Receptor-Deficient Mice

H. Bluethmann, 1998 .

Defective maintenance of T cell tolerance to a superantigen in MRL- lpr/lpr mice

J. Mountz, C. Edwards, H. Bluethmann, 1992, The Journal of experimental medicine.

Defective M_aintenance of T cell Tolerance to a Superantigen in MRI..lpr/lpr Mice

J. Mountz, C. Edwards, H. Bluethmann, 1992 .

Lack of β-Amyloidosis in transgenic mice expressing low levels of familial Alzheimer's disease missense mutations

P. Malherbe, H. Bluethmann, J. Richards, 1996, Neurobiology of Aging.

PS2APP Transgenic Mice, Coexpressing hPS2mut and hAPPswe, Show Age-Related Cognitive Deficits Associated with Discrete Brain Amyloid Deposition and Inflammation

J. Kemp, J. Kew, G. Higgins, 2003, The Journal of Neuroscience.

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

S. Prusiner, H. Lipp, S. DeArmond, 1992, Nature.

Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self- reactive T cells

Pingar Yang, J. Mountz, H. Bluethmann, 1996, The Journal of experimental medicine.

Autoimmunity due to defective Nur77, Fas, and TNF-RI apoptosis.

J. Mountz, C. Edwards, H. Bluethmann, 1996, Advances in experimental medicine and biology.

T-independent activation of B cells by vesicular stomatitis virus: no evidence for the need of a second signal.

R. Zinkernagel, T. Fehr, M. Bachmann, 1996, Cellular immunology.

A schizophrenia-related sensorimotor deficit links alpha 3-containing GABAA receptors to a dopamine hyperfunction.

R. Malenka, N. Hagenbuch, J. Feldon, 2005, Proceedings of the National Academy of Sciences of the United States of America.

2-transgenic Mice β Virus C 4 in BALB / c and T-Cell Receptor V Activation of Natural Killer Cells by Mouse Mammary Tumor

H. Bluethmann, Wei-Zen Wei, A. Iglesias, 2006 .

Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

J. Benson, H. Bluethmann, J. Fritschy, 1999, Nature.

Severe Impairment of NMDA Receptor Function in Mice Carrying Targeted Point Mutations in the Glycine Binding Site Results in Drug-Resistant Nonhabituating Hyperactivity

J. Kemp, J. Kew, G. Higgins, 2002, The Journal of Neuroscience.

Functional Consequences of Reduction in NMDA Receptor Glycine Affinity in Mice Carrying Targeted Point Mutations in the Glycine Binding Site

J. Kemp, J. Kew, V. Mutel, 2000, The Journal of Neuroscience.

Leishmania major infection in major histocompatibility complex class II-deficient mice: CD8+ T cells do not mediate a protective immune response.

H. Bluethmann, U. Ritter, H. Moll, 1996, Immunobiology.

In vivo hepatocyte proliferation is inducible through a TNF and IL-6-independent pathway

G. Ciliberto, V. Poli, A. Columbano, 1998, Oncogene.

Alternate Mucosal Immune System: Organized Peyer’s Patches Are Not Required for IgA Responses in the Gastrointestinal Tract1

J. Mcghee, H. Kiyono, Masafumi Yamamoto, 2000, The Journal of Immunology.

Interleukin-4-deficient BALB/c mice develop an enhanced Th1-like response but control cardiac inflammation following Borrelia burgdorferi infection.

A. Satoskar, H. Bluethmann, S. Telford, 2000, FEMS microbiology letters.

MHC class II molecules are not required for survival of newly generated CD4+ T cells, but affect their long-term life span.

H. Arakawa, H. Bluethmann, Takeyuki Shimizu, 1996, Immunity.

In interleukin‐4‐deficient mice, alum not only generates T helper 1 responses equivalent to Freund's complete adjuvant, but continues to induce T helper 2 cytokine production

H. Bluethmann, J. Brewer, J. Alexander, 1996, European journal of immunology.

Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in trans.

K. Rajewsky, H. Bluethmann, D. Kitamura, 1993, The EMBO journal.

Tumor necrosis factor induces tumor necrosis via tumor necrosis factor receptor type 1-expressing endothelial cells of the tumor vasculature.

D. Männel, T. Luther, H. Bluethmann, 2000, The American journal of pathology.

Aged mice exhibit in vivo defective peripheral clonal deletion of Db/H-Y reactive CD8+ T cells

H. Hsu, J. Mountz, H. Bluethmann, 2001, Mechanisms of Ageing and Development.

Transgenic Mice for Analysis of T Cell Development

H. Bluethmann, M. Steinmetz, 1990 .

Expression of a transgenic T cell receptor beta chain enhances collagen- induced arthritis

H. Loetscher, H. Bluethmann, L. Mori, 1992, The Journal of experimental medicine.

Multivalent structure of an αβT cell receptor

B. Alarcón, H. Bluethmann, M. Álvarez-Mon, 1999 .

Tumor Necrosis Factor Receptors (Tnfr) in Mouse Fibroblasts Deficient in Tnfr1 or Tnfr2 are Signaling Competent and Activate the Mitogen-activated Protein Kinase Pathway with Differential Kinetics*

W. Lesslauer, H. Bluethmann, M. Moore, 1996, The Journal of Biological Chemistry.

Enhancement of the NMDA receptor function by reduction of glycine transporter-1 expression

K. Vogt, H. Bluethmann, H. Mohler, 2004, Neuroscience Letters.

Trace Amine-Associated Receptor 1 Modulates Dopaminergic Activity

J. Moreau, B. Bettler, H. Bluethmann, 2008, Journal of Pharmacology and Experimental Therapeutics.

Apol I transcriptionalbodyassociated with VSG mono-allelic expression in Trypanosoma brucei

H. Bluethmann, C. Blum, C. Haller, 2022 .

Prolonged contraction-relaxation cycle of fast-twitch muscles in parvalbumin knockout mice.

G. Vrbóva, P. Nicotera, B. Schwaller, 1999, American journal of physiology. Cell physiology.

erratum: Benzodiazepine actions mediated by specific γ-aminobutyric acidA receptor subtypes

J. Benson, H. Bluethmann, J. Fritschy, 2000, Nature.

MACROPHAGE ACTIVATION‐INDUCED CELL DEATH IS MEDIATED BY FAS LIGAND AND TNF: 458

J. Mountz, H. Bluethmann, T. Zhou, 1997 .

Autoimmune disease results from multiple interactive defects in apoptosis induction molecules and signaling pathways.

J. Mountz, C. Edwards, H. Bluethmann, 1996, Behring Institute Mitteilungen.

Increased susceptibility of fas mutant MRL-lpr/lpr mice to staphylococcal enterotoxin B-induced septic shock.

J. Mountz, C. Edwards, H. Bluethmann, 1995, Journal of immunology.

A fas antigen receptor mutation allows development of toxic shock syndrome toxin-1-induced lethal shock in V beta 8.2 T-cell receptor transgenic mice.

J. Mountz, C. Edwards, H. Bluethmann, 1995, Pathobiology : journal of immunopathology, molecular and cellular biology.

Metallothionein induction by restraint stress: role of glucocorticoids and IL-6.

H. Bluethmann, G. Andrews, J. Hidalgo, 2000, Cytokine.

Microglia Protect Neurons against Ischemia by Synthesis of Tumor Necrosis Factor

H. Bluethmann, K. Lambertsen, T. Deierborg, 2009, The Journal of Neuroscience.

Efficient control of gene expression by single step integration of the tetracycline system in transgenic mice

U. Certa, H. Bluethmann, N. Schultze, 1996, Nature Biotechnology.

Stress-induced enhancement of skin immune function: A role for gamma interferon.

F. Dhabhar, B. McEwen, A. Satoskar, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Genomic organization and promoter function of the murine tumor necrosis factor receptor beta gene.

R. Gentz, W. Lesslauer, H. Bluethmann, 1993, Molecular immunology.

Allelic exclusion of a T cell receptor-beta minilocus.

H. Bluethmann, M. Steinmetz, J. V. van Meerwijk, 1991, Journal of immunology.

Phenotypic analysis of TNFR1-deficient mice and characterization of TNFR1-deficient fibroblasts in vitro.

R. Zinkernagel, W. Lesslauer, F. Mackay, 1994, Circulatory shock.

Impaired neuroglial activation in interleukin‐6 deficient mice

G. Kreutzberg, L. Jones, H. Bluethmann, 1997, Glia.

Prolonged contraction-relaxation cycle of fast-twitch muscles in parvalbumin knockout mice.

G. Vrbóva, P. Nicotera, B. Schwaller, 1999, American journal of physiology. Cell physiology.

Postsynaptic clustering of gamma-aminobutyric acid type A receptors by the gamma3 subunit in vivo.

J. Benson, H. Bluethmann, J. Fritschy, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Amyloid- (cid:1) and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer’s disease mice

Xiaomin Song, H. Bluethmann, L. Ozmen, 2009 .

Severity of symptoms and demyelination in MOG‐induced EAE depends on TNFR1

K. Frei, H. Lassmann, H. Bluethmann, 1999, European journal of immunology.

A protective role for IL‐6 during early infection with Toxoplasma gondii

C. Roberts, D. Ferguson, H. Bluethmann, 1998, Parasite immunology.

Neonatal Lethality in Mice Deficient in XCE, a Novel Member of the Endothelin-converting Enzyme and Neutral Endopeptidase Family*

J. Rohrer, H. Bluethmann, B. Lenz, 1999, The Journal of Biological Chemistry.

Antiviral Activity of Tumor Necrosis Factor (TNF) Is Mediated via p55 and p75 TNF Receptors

J. Peschon, H. Bluethmann, J. Ruby, 1997, The Journal of experimental medicine.

Interleukin-6 and tumor necrosis factor-alpha type 1 receptor deficient mice reveal a role of IL-6 and TNF-alpha on brain metallothionein-I and -III regulation.

H. Bluethmann, J. Hidalgo, J. Carrasco, 1998, Brain research. Molecular brain research.