J. Grooten

发表

Generation and Biological Characterization of Membrane-bound, Uncleavable Murine Tumor Necrosis Factor (*)

P. Vandenabeele, B. Vanhaesebroeck, W. Fiers, 1995, The Journal of Biological Chemistry.

Enhancement of polymethacrylate-mediated gene delivery by Penetratin.

P. Dubruel, J. Vandekerckhove, E. Schacht, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Post‐PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties

K. Braeckmans, W. Hennink, E. Mastrobattista, 2018, Journal of controlled release : official journal of the Controlled Release Society.

CD3 x CD28 cross-interacting bispecific antibodies improve tumor cell dependent T-cell activation.

D. Eeckhout, G. De Jaeger, J. Grooten, 2005, Cancer immunology, immunotherapy : CII.

CD3 × CD28 cross-interacting bispecific antibodies improve tumor cell dependent T-cell activation

D. Eeckhout, J. Grooten, S. Schoonooghe, 2005, Cancer Immunology, Immunotherapy.

Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria

W. Fiers, P. Vandenabeele, B. Zhivotovsky, 2001, Cell Death and Differentiation.

Cholesteroid nature of free mycolic acids from M. tuberculosis.

J. Grooten, Y. Benadie, M. Deysel, 2008, Chemistry and physics of lipids.

Polymeric multilayer capsule-mediated vaccination induces protective immunity against cancer and viral infection.

Jean Paul Remon, Chris Vervaet, Bart N Lambrecht, 2012, ACS nano.

Arginine‐Rich Peptide‐Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide

Jonathan L. Kirschman, J. Grooten, H. McCarthy, 2017, Advanced healthcare materials.

A new model for intermediate molecular weight recombinant bispecific and trispecific antibodies by efficient heterodimerization of single chain variable domains through fusion to a Fab-chain.

J. Grooten, S. Schoonooghe, R. Schoonjans, 2001, Biomolecular engineering.

Fab Chains As an Efficient Heterodimerization Scaffold for the Production of Recombinant Bispecific and Trispecific Antibody Derivatives1

W. Fiers, J. Grooten, S. Schoonooghe, 2000, The Journal of Immunology.

Trispecific Antibody Derivatives Production of Recombinant Bispecific and Heterodimerization Scaffold for the Fab Chains As an Efficient

W. Fiers, J. Grooten, S. Schoonooghe, 2000 .

Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines.

G. Vanham, B. Verrier, E. van Gulck, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

Polymeric multilayer capsules in drug delivery.

Jean Paul Remon, Chris Vervaet, Gleb B Sukhorukov, 2010, Angewandte Chemie.

Differentiation of EL4 lymphoma cells by tumoral environment is associated with inappropriate expression of the large chondroitin sulfate proteoglycan PG‐M and the tumor‐associated antigen HTgp‐175

R. Contreras, W. Fiers, W. Fiers, 1998, International journal of cancer.

Designing polymeric particles for antigen delivery.

M. Willart, B. Lambrecht, J. Remon, 2011, Chemical Society reviews.

Polyelectrolyte microcapsules as antigen delivery vehicles to dendritic cells: uptake, processing, and cross-presentation of encapsulated antigens.

R. De Rycke, J. Grooten, S. D. De Smedt, 2009, Angewandte Chemie.

Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes

P. Vandenabeele, J. Tavernier, A. Van Parys, 2018, Nature Communications.

Lyophilization of Protein-Loaded Polyelectrolyte Microcapsules

C. Vervaet, S. Smedt, J. Grooten, 2011, Pharmaceutical Research.

Cytoglobin expression is upregulated in all tissues upon hypoxia: an in vitro and in vivo study by quantitative real-time PCR.

P. Carmeliet, L. Moens, S. Dewilde, 2004, Biochemical and biophysical research communications.

Efficient production of human bivalent and trivalent anti-MUC1 Fab-scFv antibodies in Pichia pastoris

J. Grooten, S. Schoonooghe, N. Mertens, 2009, BMC biotechnology.

A single step process for the synthesis of antigen laden thermosensitive microparticles

J. Remon, C. Vervaet, B. D. Geest, 2010 .

M2e-Displaying Virus-Like Particles with Associated RNA Promote T Helper 1 Type Adaptive Immunity against Influenza A

W. Fiers, S. Roels, J. Grooten, 2013, PloS one.

Macrophages Present Pinocytosed Exogenous Antigen Via MHC Class I Whereas Antigen Ingested by Receptor-Mediated Endocytosis Is Presented Via MHC Class II

M. Peppelenbosch, S. V. van Deventer, J. Grooten, 2000, The Journal of Immunology.

H-2-restricted helper hybridomas: one locus or two control dual specificity?

J. Grooten, G. Hämmerling, P. Lonai, 1982, Current topics in microbiology and immunology.

Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma

W. Fiers, P. Vandenabeele, H. Loetscher, 1992, The Journal of experimental medicine.

Nanoporous Hydrogen Bonded Polymeric Microparticles: Facile and Economic Production of Cross Presentation Promoting Vaccine Carriers

B. Lambrecht, J. Remon, R. De Rycke, 2014 .

Animal models of allergen‐induced tolerance in asthma: are T‐regulatory‐1 cells (Tr‐1) the solution for T‐helper‐2 cells (Th‐2) in asthma?

G. Joos, J. Grooten, G. Brusselle, 2006, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Spatiotemporal autophagic degradation of oxidatively damaged organelles after photodynamic stress is amplified by mitochondrial reactive oxygen species

P. Agostinis, J. Piette, J. Grooten, 2012, Autophagy.

Clinical procedure for colon carcinoma tissue sampling directly affects the cancer marker-capacity of VEGF family members

P. Pattyn, M. Peeters, J. Grooten, 2012, BMC Cancer.

Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes.

H. Pircher, G. Berx, P. De Baetselier, 2009, Blood.

Polyelectrolyte LbL microcapsules versus PLGA microparticles for immunization with a protein antigen.

R. Vandenbroucke, C. Libert, B. Gander, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Surface-engineered polyelectrolyte multilayer capsules: synthetic vaccines mimicking microbial structure and function.

M. Willart, B. Lambrecht, J. Remon, 2012, Angewandte Chemie.

Single-step formation of degradable intracellular biomolecule microreactors.

J. Remon, C. Vervaet, R. De Rycke, 2011, ACS nano.

Single-Step Formation of Degradable Intracellular Biomolecule

B. D. Geest, J. Grooten, R. Rycke, 2011 .

Facile two-step synthesis of porous antigen-loaded degradable polyelectrolyte microspheres.

J. Remon, C. Vervaet, J. Grooten, 2010, Angewandte Chemie.

Macrophage galactose‐type C‐type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation

B. Dahal, P. De Baetselier, G. Vanham, 2005, Journal of leukocyte biology.

New Recombinant Bi- and Trispecific Antibody Derivatives

J. Grooten, S. Schoonooghe, R. Schoonjans, 2001 .

Vivo Invasiveness Correlates with Reduced Tumorigenicity and Reduced Expression of the Tumor Necrosis Factor Gene in Tumor Cells

W. Fiers, B. Vanhaesebroeck, J. Grooten, 2006 .

Expression of the tumor necrosis factor gene in tumor cells correlates with reduced tumorigenicity and reduced invasiveness in vivo.

W. Fiers, M. Mareel, B. Vanhaesebroeck, 1991, Cancer research.

Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity.

M. Bertrand, P. Vandenabeele, G. Berx, 2016, Cell reports.

Cathepsin B-mediated activation of the proinflammatory caspase-11.

W. Fiers, L. de Ridder, P. Vandenabeele, 1998, Biochemical and biophysical research communications.

Tumor Necrosis Factor Induces Hyperphosphorylation of Kinesin Light Chain and Inhibits Kinesin-Mediated Transport of Mitochondria

A. Hyman, K. Vancompernolle, J. Grooten, 2000, The Journal of cell biology.

Involvement of IFN-gamma in Bacillus Calmette-Guérin-induced but not in tumor-induced sensitization to TNF-induced lethality.

W. Fiers, S. Huang, M. Aguet, 1995, Journal of immunology.

Tumoral environment triggers transcript anomalies in established tumors: induction of altered gene expression and of aberrant, truncated and B2 repeat-containing gene transcripts.

R. Contreras, J. Grooten, P. Rottiers, 1999, Neoplasia.

pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation

B. Lambrecht, J. Grooten, Nikunj M. Shukla, 2016, Proceedings of the National Academy of Sciences.

Response of TNF-hyporesponsive SPRET/Ei mice in models of inflammatory disorders

G. Kollias, C. Libert, D. Kontoyiannis, 2004, Mammalian Genome.

Inflammatory signatures for eosinophilic vs. neutrophilic allergic pulmonary inflammation reveal critical regulatory checkpoints.

J. Piette, J. Grooten, S. De Koker, 2011, American journal of physiology. Lung cellular and molecular physiology.

Tumour Necrosis Factor and Interleukin-6: Structure and Mechanism of Action of the Molecular, Cellular and in Vivo Level

W. Fiers, J. Tavernier, G. Haegeman, 1989 .

Blocking tumor cell eicosanoid synthesis by GP x 4 impedes tumor growth and malignancy.

P. Agostinis, R. Brigelius-Flohé, P. Brouckaert, 2006, Free radical biology & medicine.

Tumor Necrosis Factor: Mechanism of Action and its Potential for Anticancer Therapy

W. Fiers, C. Libert, B. Vanhaesebroeck, 1992 .

IL-15 Augments TCR-Induced CD4+ T Cell Expansion In Vitro by Inhibiting the Suppressive Function of CD25High CD4+ T Cells

J. Grooten, G. Leclercq, T. V. Van Belle, 2012, PloS one.

Macrophage reprogramming by mycolic acid promotes a tolerogenic response in experimental asthma.

P. De Baetselier, J. Grooten, K. Tournoy, 2006, American journal of respiratory and critical care medicine.

Airway IgG Counteracts Specific and Bystander Allergen-Triggered Pulmonary Inflammation by a Mechanism Dependent on FcγR and IFN-γ1

R. Pauwels, J. Grooten, K. Tournoy, 2003, The Journal of Immunology.

IFN-γ Fc Inflammation by a Mechanism Dependent on Bystander Allergen-Triggered Pulmonary Airway IgG Counteracts Specific and Pauwels and

R. Pauwels, J. Grooten, K. Tournoy, 2003 .

Acquisition by the murine host of responsiveness toward various neoplastic cell lines, but not toward self, through adoptive transfer of a helper T-lymphocyte clone with antiself specificity.

W. Fiers, J. Grooten, 1989, Cancer research.

Differential role of calcium in tumour necrosis factor-mediated apoptosis and secretion of granulocyte-macrophage colony-stimulating factor in a T cell hybridoma.

W. Fiers, P. Vandenabeele, L. Penning, 1997, Cytokine.

Number : DAIMD 1703-1-0222 TITLE : Detection of Serum Lysophosphatidic Acids Using Affinity Binding and Surface Enhanced Laser Desorption / Ionization ( SELDI ) Time of Flight Mass Spectrometry

J. Grooten, K. Meerschaert, Ján, 2022 .

Type I Interferons Interfere with the Capacity of mRNA Lipoplex Vaccines to Elicit Cytolytic T Cell Responses.

G. Vanham, J. Grooten, X. Saelens, 2016, Molecular therapy : the journal of the American Society of Gene Therapy.

Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour necrosis factor (TNF) receptor is mediated by endogenous murine TNF.

W. Fiers, P. Vandenabeele, J. Grooten, 1995, Cytokine.

Where asthma and hypersensitivity pneumonitis meet and differ: noneosinophilic severe asthma.

J. Grooten, P. Bogaert, K. Tournoy, 2009, The American journal of pathology.

Cysteinyl Leukotrienes Mediate Histamine Hypersensitivity Ex Vivo by Increasing Histamine Receptor Numbers

M. Peppelenbosch, S. V. van Deventer, J. Grooten, 1999, Molecular medicine.

Antigen presentation by local macrophages promotes nonallergic airway responses in sensitized mice.

J. Grooten, T. V. Van Belle, S. Sehra, 2003, American journal of respiratory cell and molecular biology.

Effect of bcl-2 proto-oncogene expression on cellular sensitivity to tumor necrosis factor-mediated cytotoxicity.

W. Fiers, John Calvin Reed, T. Miyashita, 1993, Oncogene.

New asthma biomarkers: lessons from murine models of acute and chronic asthma.

J. Foidart, A. Noël, J. Piette, 2009, American journal of physiology. Lung cellular and molecular physiology.

E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo

P. De Baetselier, H. Smits, J. Grooten, 2015, Scientific Reports.

IL-15 and IL-15Ralpha in CD4+T cell immunity.

J. Grooten, T. V. Van Belle, 2005, Archivum immunologiae et therapiae experimentalis.

Lipoplexes carrying mRNA encoding Gag protein modulate dendritic cells to stimulate HIV-specific immune responses.

G. Vanham, E. van Gulck, J. Grooten, 2013, Nanomedicine.

Via MHC Class II Ingested by Receptor-Mediated Endocytosis Antigen Via MHC Class I Whereas Antigen Macrophages Present Pinocytosed Exogenous

S. Deventer, M. Peppelenbosch, J. Grooten, 2000 .

IL-4 acts synergistically on the IL-2 response of an autoreactive T-cell clone; synergism correlates with increased intracellular IL-2, but not with a modified IL-2 receptor expression.

W. Fiers, P. Vandenabeele, J. Grooten, 1990, Cellular immunology.

Lipopolysaccharide regulates macrophage fluid phase pinocytosis via CD14-dependent and CD14-independent pathways.

M. Peppelenbosch, S. V. van Deventer, T. ten Hove, 1999, Blood.

Polymeric multilayer capsules delivering biotherapeutics.

J. Remon, C. Vervaet, J. Grooten, 2011, Advanced drug delivery reviews.

Author ' s personal copy Polymeric multilayer capsules delivering biotherapeutics ☆

J. Remon, C. Vervaet, B. D. Geest, 2011 .

Interleukin-15 redirects the outcome of a tolerizing T-cell stimulus from apoptosis to anergy.

J. Grooten, T. V. Van Belle, P. Rottiers, 2000, Blood.

Original Contribution Blocking tumor cell eicosanoid synthesis by GPx4 impedes tumor growth and malignancy

P. Agostinis, P. Brouckaert, J. Grooten, 2006 .

Quiescence-inducing and antiapoptotic activities of IL-15 enhance secondary CD4+ T cell responsiveness to antigen.

W. Fiers, J. Grooten, V. Goossens, 1998, Journal of immunology.

Atractyloside‐induced release of cathepsin B, a protease with caspase‐processing activity

W. Fiers, P. Vandenabeele, K. Vancompernolle, 1998, FEBS letters.

Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern

J. Grooten, M. Baird, E. Lanckacker, 2011, European journal of immunology.

Mycobacterium tuberculosis‐associated synthetic mycolates differentially exert immune stimulatory adjuvant activity

J. Grooten, M. Baird, J. Verschoor, 2016, European journal of immunology.

Induction of IL‐15 by TCR/CD3 aggregation depends on IFN‐γ and protects against apoptosis of immature thymocytes in vivo

A. Billiau, J. Grooten, G. Leclercq, 2002, Clinical and experimental immunology.

The Oxidative Metabolism of Glutamine A MODULATOR OF REACTIVE OXYGEN INTERMEDIATE-MEDIATED CYTOTOXICITY OF TUMOR NECROSIS FACTOR IN L929 FIBROSARCOMA CELLS*

W. Fiers, J. Grooten, V. Goossens, 1995 .

Polyelectrolyte capsules-containing HIV-1 p24 and poly I:C modulate dendritic cells to stimulate HIV-1-specific immune responses.

G. Vanham, E. van Gulck, J. Grooten, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Structure–function relationships of the antigenicity of mycolic acids in tuberculosis patients

M. Beukes, J. Grooten, M. Balogun, 2010, Chemistry and physics of lipids.

Macrophages induce cellular immunity by activating Th1 cell responses and suppressing Th2 cell responses.

W. Fiers, W. Fiers, J. Grooten, 1998, Journal of immunology.

PH1-derived bivalent bibodies and trivalent tribodies bind differentially to shed and tumour cell-associated MUC1.

L. Vervoort, J. Grooten, S. Schoonooghe, 2010, Protein engineering, design & selection : PEDS.

Anti-micrococcus antibodies recognize an antigenic marker of confluent mouse lymphoid cell lines

J. Grooten, P. Baetselier, R. Hamers, 1980, Nature.

Cell membrane permeabilization and cellular collapse, followed by loss of dehydrogenase activity: early events in tumour necrosis factor-induced cytotoxicity.

W. Fiers, B. Vanhaesebroeck, J. Grooten, 1993, Cytokine.

The immunomodulatory effect of anti‐Micrococcus luteus antibodies I. Effect on in vitro rabbit T cell functions

P. De Baetselier, J. Grooten, R. Hamers, 1983, European journal of immunology.

Membrane interaction and cellular internalization of penetratin peptides.

A. Prochiantz, J. Vandekerckhove, A. Joliot, 2004, European journal of biochemistry.

Nanoporous polyelectrolyte vaccine microcarriers. A formulation platform for enhancing humoral and cellular immune responses.

B. Lambrecht, J. Remon, R. De Rycke, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Phosphatidyl serine exposure during apoptosis precedes release of cytochrome c and decrease in mitochondrial transmembrane potential

W. Fiers, P. Vandenabeele, G. van Loo, 2000, FEBS letters.

Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity.

W. Fiers, W. Fiers, J. Grooten, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of Caspases Increases the Sensitivity of L929 Cells to Necrosis Mediated by Tumor Necrosis Factor

W. Fiers, P. Vandenabeele, G. van Loo, 1998, The Journal of experimental medicine.

Coadministration of a Plasmid Encoding HIV-1 Gag Enhances the Efficacy of Cancer DNA Vaccines.

G. Vandermeulen, V. Préat, J. Grooten, 2016, Molecular therapy : the journal of the American Society of Gene Therapy.

GM-CSF treatment prevents respiratory syncytial virus-induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation.

M. Willart, B. Lambrecht, J. Grooten, 2016, The Journal of allergy and clinical immunology.

Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12

M. Willart, B. Lambrecht, B. D. Geest, 2017, Scientific Reports.

Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes

P. Vandenabeele, J. Tavernier, A. Van Parys, 2018, Nature Communications.

Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGE

J. Vandekerckhove, K. Vancompernolle, F. Chaplen, 2002, Proceedings of the National Academy of Sciences of the United States of America.

A Caspase-activated Factor (CAF) Induces Mitochondrial Membrane Depolarization and Cytochrome c Release by a Nonproteolytic Mechanism

P. Vandenabeele, K. Vancompernolle, J. Grooten, 1998, The Journal of experimental medicine.

The 55-kDa Tumor Necrosis Factor Receptor Induces Clustering of Mitochondria through Its Membrane-proximal Region*

W. Fiers, P. Vandenabeele, G. Haegeman, 1998, The Journal of Biological Chemistry.

Regulation of tumor necrosis factor-induced, mitochondria- and reactive oxygen species-dependent cell death by the electron flux through the electron transport chain complex I.

D. Pipeleers, J. Grooten, V. Goossens, 1999, Antioxidants & redox signaling.

The Oxidative Metabolism of Glutamine

W. Fiers, J. Grooten, V. Goossens, 1996, The Journal of Biological Chemistry.

pH-Degradable Mannosylated Nanogels for Dendritic Cell Targeting.

S. van Calenbergh, N. Ayres, Vimal Kumar, 2016, Biomacromolecules.

Spontaneous Protein Adsorption on Graphene Oxide Nanosheets Allowing Efficient Intracellular Vaccine Protein Delivery.

B. Lambrecht, T. De Beer, D. Deforce, 2016, ACS applied materials & interfaces.

Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice.

J. Gustafsson, J. Grooten, B. Stijlemans, 2009, The Journal of clinical investigation.

Optimizing expression and purification from cell culture medium of trispecific recombinant antibody derivatives.

Nico Mertens, Jannick Leoen, An Willems, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Specific suppression elicited by EL4 lymphoma cells in syngeneic mice. Specificity includes self‐antigens on EL4

W. Fiers, J. Grooten, G. Leroux‐Roel, 1987, European journal of immunology.

Alloinduced suppression and cytotoxicity: two functions of a single cell.

W. Fiers, J. Grooten, G. Leroux-Roels, 1987, Immunology letters.

Lysophosphatidic acid affinity chromatography reveals pyruvate kinase as a specific LPA-binding protein

G. Prestwich, J. Vandekerckhove, J. Grooten, 2005, Biological chemistry.

pH-dependent aggregation and secretion of soluble monomeric influenza hemagglutinin

W. Fiers, J. Grooten, P. Vanlandschoot, 2014, Archives of Virology.

Mycolic acids for the control of tuberculosis

J. Grooten, Gianna Sekanka, M. Baird, 2007 .

Boosting In Planta Production of Antigens Derived from the Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) and Subsequent Evaluation of Their Immunogenicity

Hans Nauwynck, Johan Grooten, A. Depicker, 2014, PloS one.

Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation

H. Hammad, M. Willart, B. Lambrecht, 2015, Mucosal Immunology.

Type I Interferons Modulate CD8+ T Cell Immunity to mRNA Vaccines.

J. Grooten, A. De Beuckelaer, S. De Koker, 2017, Trends in molecular medicine.

Redox regulation of TNF signaling

W. Fiers, P. Vandenabeele, K. Vancompernolle, 1999, BioFactors.

Tumor Necrosis Factor-induced Microtubule Stabilization Mediated by Hyperphosphorylated Oncoprotein 18 Promotes Cell Death*

W. Fiers, M. Mann, K. Vancompernolle, 2000, The Journal of Biological Chemistry.

Lipoprotein I, a TLR2/4 Ligand Modulates Th2-Driven Allergic Immune Responses

P. De Baetselier, J. Grooten, H. Revets, 2005, The Journal of Immunology.

Challenges and advances towards the rational design of mRNA vaccines.

G. Vanham, J. Grooten, X. Saelens, 2013, Trends in molecular medicine.

Towards understanding the functional diversity of cell wall mycolic acids of Mycobacterium tuberculosis.

J. Grooten, M. Baird, J. Verschoor, 2012, Progress in lipid research.

Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells.

W. Fiers, P. Vandenabeele, B. Vanhaesebroeck, 1995, Journal of immunology.

Do-it-yourself: construction of a custom cDNA macroarray platform with high sensitivity and linear range

P. De Baetselier, P. Brouckaert, J. Grooten, 2011, BMC biotechnology.

An ongoing in vivo immune response affects the abundancy and differentiation of lymphokine-activated killer cell precursors, but does not influence their broad spectrum target reactivity.

W. Fiers, B. Vanhaesebroeck, J. Grooten, 1989, Journal of immunology.

11 – Role of Reactive Oxygen Species in Tumor Necrosis Factor Toxicity

W. Fiers, P. Vandenabeele, K. Vancompernolle, 2000 .

Multiple signal transduction pathways regulate TNF-induced actin reorganization in macrophages: inhibition of Cdc42-mediated filopodium formation by TNF.

W. Fiers, G. E. Jones, G. Haegeman, 1999, Journal of immunology.

TNF Cdc 42-Mediated Filopodium Formation by in Macrophages : Inhibition of Regulate TNF-Induced Actin Reorganization Multiple Signal Transduction Pathways and

W. Fiers, G. Haegeman, A. Ridley, 1998 .

Mycolates of Mycobacterium tuberculosis modulate the flow of cholesterol for bacillary proliferation in murine macrophages

J. Grooten, M. Baird, J. Verschoor, 2017, Journal of Lipid Research.

TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis.

W. Fiers, P. Vandenabeele, G. Haegeman, 1995, Journal of inflammation.

Induction of Unresponsiveness to Tumor Necrosis Factor (TNF) after Autocrine TNF Expression Requires TNF Membrane Retention*

G. Haegeman, B. Vanhaesebroeck, W. Fiers, 1998, The Journal of Biological Chemistry.

Engineering Polymer Hydrogel Nanoparticles for Lymph Node-Targeted Delivery.

Jiwei Cui, Lorenzo Albertazzi, Frank Caruso, 2016, Angewandte Chemie.

Biodegradable Polyelectrolyte Microcapsules: Antigen Delivery Tools with Th17 Skewing Activity after Pulmonary Delivery

J. Grooten, S. D. De Smedt, B. D. De Geest, 2009, The Journal of Immunology.

Hybrid pulmonary surfactant-coated nanogels mediate efficient in vivo delivery of siRNA to murine alveolar macrophages.

J. Grooten, S. D. De Smedt, J. Demeester, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Phosphorylation by Protein Kinase CK2 Modulates the Activity of the ATP Binding Cassette A1 Transporter*

J. Tavernier, J. Vandekerckhove, M. Lensink, 2004, Journal of Biological Chemistry.

Cholesterol‐sensing liver X receptors stimulate Th2‐driven allergic eosinophilic asthma in mice

M. Willart, B. Lambrecht, J. Gustafsson, 2016, Immunity, inflammation and disease.

Efficient heterodimerization of recombinant bi- and trispecific antibodies

J. Grooten, R. Schoonjans, A. Willems, 2000, Bioseparation.

Transcriptome analysis of monocyte-HIV interactions

P. De Baetselier, G. Vanham, J. Grooten, 2010, Retrovirology.

Role of endoplasmic reticulum depletion and multidomain proapoptotic BAX and BAK proteins in shaping cell death after hypericin‐mediated photodynamic therapy

L. Scorrano, P. Agostinis, D. Hartmann, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Innate imprinting of murine resident alveolar macrophages by allergic bronchial inflammation causes a switch from hypoinflammatory to hyperinflammatory reactivity.

N. Van Rooijen, J. Grooten, S. De Koker, 2012, The American journal of pathology.

The first unique synthetic mycobacterial cord factors

J. Grooten, M. Baird, J. R. Dulayymi, 2009 .

The Mycobacterium tuberculosis cell wall component mycolic acid elicits pathogen‐associated host innate immune responses

P. De Baetselier, J. Grooten, J. Verschoor, 2005, European journal of immunology.

New strategies in polypeptide and antibody synthesis: an overview.

Filip Devos, Dominique Vlieghe, Andrew Kelly, 2004, Cancer biotherapy & radiopharmaceuticals.

Th2-Driven Allergic Immune Responses Lipoprotein I, a TLR2/4 Ligand Modulates

J. Grooten, H. Revets, G. Pynaert, 2004 .

Buffering properties of cationic polymethacrylates are not the only key to successful gene delivery.

P. Dubruel, J. Vandekerckhove, E. Schacht, 2004, Biomacromolecules.

Aspergillus fumigatus Recognition by Dendritic Cells Negatively Regulates Allergic Lung Inflammation Through a TLR2/MyD88 Pathway.

J. Grooten, R. Beyaert, O. Denis, 2020, American journal of respiratory cell and molecular biology.