P. Halushka

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Altered macrophage function in tumor necrosis factor α- and endotoxin-induced tolerance

B. Zingarelli, A. Caputi, M. Makhlouf, 1995 .

Endotoxin Activation of Eicosanoid Production by Macrophages

P. Halushka, J. Cook, J. Geisel, 1993 .

Human internal mammary artery produces more prostacyclin than saphenous vein.

F. Crawford, P. Halushka, L. Olanoff, 1986, The Journal of thoracic and cardiovascular surgery.

Original Article β-Arrestin 2: a Negative Regulator of Inflammatory Responses in Polymorphonuclear Leukocytes

L. Luttrell, B. Zingarelli, P. Halushka, 2008 .

Eicosanoids in the Cardiovascular and Renal Systems

P. Halushka, D. Mais, 1988, Advances in Eicosanoid Research.

Urinary excretion of prostaglandin E like material and kallikrein: effects of furosemide.

P. Halushka, H. Margolius, H. Allen, 1979, Prostaglandins.

Altered platelet function in diabetes mellitus.

P. Halushka, J. Colwell, J. Sagel, 1976, Diabetes.

Progesterone regulation of vascular thromboxane A(2) receptors in rhesus monkeys.

R. Minshall, P. Halushka, K. Hermsmeyer, 2001, American Journal of Physiology. Heart and Circulatory Physiology.

miR-145a Regulates Pericyte Dysfunction in a Murine Model of Sepsis.

Pengfei Li, B. Zingarelli, A. Goodwin, 2020, The Journal of infectious diseases.

Thromboxane, prostacyclin, and leukotrienes in cerebral ischemia

E. Hogan, P. Halushka, C. Hsu, 1986, Neurology.

Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression.

L. Luttrell, P. Halushka, J. Cook, 2007, Molecular immunology.

Studies on the beneficial effects of aspirin in endotoxic shock. Relationship to inhibition of arachidonic acid metabolism.

P. Halushka, J. Cook, W. C. Wise, 1983, The American journal of medicine.

Alterations in plasma levels and complexing of Gc (vitamin D-binding protein) in rats with endotoxic shock.

P. Halushka, J. Cook, R. Galbraith, 1989, Circulatory shock.

Role of thromboxane, prostaglandins and leukotrienes in endotoxic and septic shock

P. Halushka, J. Cook, H. Ball, 2004, Intensive Care Medicine.

Carbon dioxide is the major metabolite of quercetin in humans.

P. Halushka, T. Walle, U. Walle, 2001, The Journal of nutrition.

Disposition and metabolism of the flavonoid chrysin in normal volunteers.

P. Halushka, T. Walle, U. Walle, 2001, British journal of clinical pharmacology.

Carbon dioxide is the major metabolite of quercetin in humans.

P. Halushka, T. Walle, U. Walle, 2001, The Journal of nutrition.

A controlled trial of amlodipine for cocaine dependence: a negative report.

K. Brady, R. Woolson, P. Halushka, 2005, Journal of substance abuse treatment.

Vascular disease in diabetes: pathophysiological mechanisms and therapy.

P. Halushka, M. Lopes-Virella, J. Colwell, 1979, Archives of internal medicine.

New concepts about the pathogenesis of atherosclerosis in diabetes mellitus.

P. Halushka, M. Lopes-Virella, P. Winocour, 1983, The American journal of medicine.

Prostacyclin and thromboxane A2 formation is increased in human sepsis syndrome. Effects of cyclooxygenase inhibition.

G. Bernard, C. Metz, B. Swindell, 1991, The American review of respiratory disease.

Opportunities for microRNAs in the Crowded Field of Cardiovascular Biomarkers.

M. Halushka, A. Goodwin, P. Halushka, 2019, Annual review of pathology.

Heterotrimeric Gα(i) proteins are regulated by lipopolysaccharide and are anti-inflammatory in endotoxemia and polymicrobial sepsis.

L. Birnbaumer, Pengfei Li, B. Zingarelli, 2011, Biochimica et biophysica acta.

Lysophosphatidic Acid Inhibits Bacterial Endotoxin-Induced Pro-Inflammatory Response: Potential Anti-Inflammatory Signaling Pathways

B. Zingarelli, P. Halushka, J. Cook, 2008, Molecular medicine.

Generation of a new immortalized human lung pericyte cell line: a promising tool for human lung pericyte studies

Pengfei Li, A. Goodwin, P. Halushka, 2020, Laboratory Investigation.

Genetic variation in cyclooxygenase 1: Effects on response to aspirin

M. Halushka, P. Halushka, Linda P. Walker, 2003, Clinical pharmacology and therapeutics.

Testosterone increases human platelet thromboxane A2 receptor density and aggregation responses.

P. Halushka, A. A. Ajayi, R. Mathur, 1995, Circulation.

Increased platelet thromboxane synthesis in diabetes mellitus.

P. Halushka, J. Colwell, C. Loadholt, 1981, The Journal of laboratory and clinical medicine.

Antiaggregatory activity of 8-epi-prostaglandin F2 alpha and other F-series prostanoids and their binding to thromboxane A2/prostaglandin H2 receptors in human platelets.

P. Halushka, P. Wong, Khin Nyein Yin, 1994, The Journal of pharmacology and experimental therapeutics.

Platelet adhesion and aggregation in diabetes mellitus.

P. Halushka, J. Colwell, J. Sagel, 1979, Metabolism: clinical and experimental.

Alteration of thrornboxane and prostacyclin levels in experimental spinal cord injury

P. Perot, E. Hogan, P. Halushka, 1985, Neurology.

Do Platelets Have Anything To Do With Diabetic Microvascular Disease?

P. Halushka, P. Winocour, J. Colwell, 1983, Diabetes.

Thromboxane, prostaglandin and leukotriene receptors.

P. Halushka, T. Morinelli, D. Mais, 1989, Annual review of pharmacology and toxicology.

production by macrophages from endotoxin-tolerant rats stimulated cAMP 2 Increased prostacyclin and PGE

M. Makhlouf, P. Halushka, J. Cook, 2016 .

Cloning and characterization of an endogenous COS-7 cell thromboxane A2 receptor.

P. Halushka, K. Becker, M. Ullian, 1998, Biochimica et biophysica acta.

Increased prostacyclin and PGE2 stimulated cAMP production by macrophages from endotoxin-tolerant rats.

M. Makhlouf, P. Halushka, J. Cook, 1998, American journal of physiology. Cell physiology.

P. Halushka, R. Mathur, K. Higashiura, 1997, Journal of cardiovascular pharmacology.

Alterations in macrophage G proteins are associated with endotoxin tolerance.

M. Makhlouf, P. Halushka, J. Cook, 1996, Biochimica et biophysica acta.

Co-Expression of Specific G-Protein α Subunits Alters the Affinity of Thromboxane A2 Receptors

P. Halushka, T. Gettys, G. P. Meier, 1996 .

Inhibition of ligand binding to thromboxane A2/prostaglandin H2 receptors by diethylpyrocarbonate. Protection by receptor ligands and reversal by hydroxylamine.

K. Schrör, P. Halushka, K. Davis-Bruno, 1995, Biochemical pharmacology.

Agonist-induced phosphorylation of human platelet TXA2/PGH2 receptors.

P. Halushka, D. Mais, A. Okwu, 1994, Biochimica et biophysica acta.

Thromboxane A2 receptors in equine monocytes: identification of a new subclass of TXA2 receptors

P. Halushka, J. Cook, J. Moore, 1993, Journal of leukocyte biology.

Characterization of thromboxane A2/prostaglandin H2 receptors in human vascular smooth muscle cells.

P. Halushka, T. Morinelli, D. Mais, 1990, Life sciences.

Radioligand binding assays for thromboxane A2/prostaglandin H2 receptors.

P. Halushka, T. Morinelli, D. Mais, 1990, Methods in enzymology.

Eicosanoids in sepsis and its sequelae

P. Halushka, J. Cook, G. Tempel, 1988 .

Interactions of dihydropyridine Ca2+ channel agonists with the human platelet thromboxane A2/prostaglandin H2 receptor.

P. Halushka, D. Mais, P. Mayeux, 1991, European journal of pharmacology.

PEROXISOME PROLIFERATOR‐ACTIVATED RECEPTOR‐GAMMA AGONISTS MODULATE MACROPHAGE ACTIVATION BY GRAM‐NEGATIVE AND GRAM‐POSITIVE BACTERIAL STIMULI

G. Gilkeson, B. Zingarelli, P. Halushka, 2003, Shock.

14 – Platelet Involvement in Diabetes Mellitus

P. Halushka, P. Winocour, J. Colwell, 1985 .

Platelet Function During Continuous Insulin Infusion Treatment in Insulin-dependent Diabetic Patients

R. Mayfield, P. Halushka, M. Lopes-Virella, 1985, Diabetes.

Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation.

Pengfei Li, G. Gilkeson, L. Luttrell, 2011, Molecular immunology.

Beta‐arrestin 2 negatively regulates sepsis‐induced inflammation

A. Bitto, L. Luttrell, B. Zingarelli, 2010, Immunology.

Is the training of biomedical scientists at a crossroads?

P. Halushka, Edward L Krug, 2009, Academic medicine : journal of the Association of American Medical Colleges.

Involvement of Gi proteins and Src tyrosine kinase in TNFα production induced by lipopolysaccharide, group B Streptococci and Staphylococcus aureus

G. Teti, P. Halushka, J. Cook, 2003 .

Elevated prostaglandin production in cultured cells from a patient with fibrodysplasia ossificans progressiva.

S. Spicer, R. Miller, P. Halushka, 1978, Prostaglandins.

1-(carboxybenzyl)imidazole-5-acrylic acids: potent and selective angiotensin II receptor antagonists.

P. Halushka, T. Morinelli, N. Hamanaka, 1991 .

Endothelial progenitor cells and a stromal cell-derived factor-1α analogue synergistically improve survival in sepsis.

B. Zingarelli, A. Goodwin, P. Halushka, 2014, American journal of respiratory and critical care medicine.

Effects of a pyridine derivative thromboxane synthetase inhibitor and its inactive isomer in endotoxic shock in the rat

P. Halushka, J. Cook, E. Wagner, 1983, British journal of pharmacology.

Prostaglandin J(2) inhibition of mesangial cell iNOS expression.

G. Gilkeson, J. Oates, P. Halushka, 2001, Clinical immunology.

Inhibition of Mesangial Cell Nitric Oxide in MRL/lpr Mice by Prostaglandin J2 and Proliferator Activation Receptor-γ Agonists1

J. Morrow, G. Gilkeson, J. Oates, 2000, The Journal of Immunology.

Thromboxane A2 receptors.

P. Halushka, K. Davis-Bruno, C. J. Allan, 1995, Journal of lipid mediators and cell signalling.

Toll-like Receptor-Induced Inflammatory Cytokines are Suppressed by Gain of Function or Overexpression of Gαi2 Protein

R. Neubig, Pengfei Li, B. Zingarelli, 2012, Inflammation.

Characterization of an 125I-labeled thromboxane A2/prostaglandin H2 receptor agonist.

P. Halushka, D. Knapp, T. Morinelli, 1989, The Journal of pharmacology and experimental therapeutics.

Inhibition of platelet thromboxane synthesis by 7-(1-imidazolyl) heptanoic acid: dissociation from inhibition of aggregation.

P. Halushka, D. Knapp, L. Grimm, 1981, Thrombosis research.

Temporal profile of thromboxane-prostacyclin imbalance in experimental spinal cord injury

K. Spicer, E. Hogan, P. Halushka, 1988, Journal of the Neurological Sciences.

Human platelets attenuate oxidant injury in isolated rabbit lungs.

J. Heffner, P. Halushka, J. Cook, 1988, Journal of applied physiology.

Sex steroid regulation of thromboxane A2 receptors in cultured rat aortic smooth muscle cells.

P. Halushka, K. Matsuda, M. Ullian, 1995, Prostaglandins.

Testosterone increases thromboxane A2 receptors in cultured rat aortic smooth muscle cells.

P. Halushka, R. Mathur, A. Masuda, 1991, Circulation research.

TOLL-LIKE RECEPTOR 4 COUPLED GI PROTEIN SIGNALING PATHWAYS REGULATE EXTRACELLULAR SIGNAL-REGULATED KINASE PHOSPHORYLATION AND AP-1 ACTIVATION INDEPENDENT OF NFκB ACTIVATION

P. Halushka, J. Cook, G. Tempel, 2004 .

Androstenedione increases thromboxane A2 receptors in human erythroleukemia cells.

P. Halushka, R. Mathur, K. Higashiura, 1996, Life sciences.

Human platelets modulate edema formation in isolated rabbit lungs.

J. Heffner, P. Halushka, J. Cook, 1989, The Journal of clinical investigation.

An impaired natriuretic peptide hormone system may play a role in COVID‐19 severity in vulnerable populations

M. Currie, P. Halushka, D. Zimmer, 2020, FASEB bioAdvances.

Dazoxiben in human sepsis and adult respiratory distress syndrome

P. Halushka, L. Olanoff, P. Hunt, 1985, Clinical pharmacology and therapeutics.

The Thromboxane Receptor Antagonist PBT-3, a Hepoxilin Stable Analog, Selectively Antagonizes the TPα Isoform in Transfected COS-7 Cells

P. Halushka, N. Qiao, D. Reynaud, 2003, Journal of Pharmacology and Experimental Therapeutics.

Platelet Arachidonic Acid Metabolism and Eicosanoid Receptors

P. Halushka, C. J. Allan, 1997 .

Characterization of Thromboxane A2/Prostaglandin H2 Receptors

P. Halushka, D. Mais, D. Saussy, 1988 .

Platelet and vascular smooth muscle thromboxane A2/prostaglandin H2 receptors.

P. Halushka, D. Mais, D. Saussy, 1987, Federation proceedings.

Platelet function and diabetes mellitus.

P. Halushka, J. Colwell, J. Sagel, 1978, The Medical clinics of North America.

Rationale for antiplatelet agents in diabetic vascular disease.

P. Halushka, J. Colwell, K. Sarji, 1978, Advances in experimental medicine and biology.

Characterization of human peripheral blood monocyte thromboxane A2 receptors.

P. Halushka, C. J. Allan, 1994, The Journal of pharmacology and experimental therapeutics.

Effects of two magainin peptides on eicosanoid release from rat peritoneal macrophages

P. Halushka, J. Cook, J. Geisel, 1993, Antimicrobial Agents and Chemotherapy.

Thromboxane A2 and Other Eicosanoids

P. Halushka, S. Pawate, M. Martin, 1997 .

13-Azaprostanoic acid: a specific antagonist of the human blood platelet thromboxane/endoperoxide receptor.

G. L. Le Breton, P. Halushka, D. Venton, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Oleic acid-induced pulmonary injury in rats: potential role of sulfidopeptide leukotrienes.

K. Spicer, P. Halushka, J. Cook, 1988, Circulatory shock.

Thromboxane and stable prostaglandin endoperoxide analogs stimulate water permeability in the toad urinary bladder.

P. Halushka, R. Burch, 1980, The Journal of clinical investigation.

Altered Guanine Nucleotide Protein Function: Potential Role in Endotoxin Tolerance

P. Halushka, J. Cook, Wise Wc, 1993 .

Cultured human vascular smooth muscle cells with functional thromboxane A2 receptors: measurement of U46619-induced 45calcium efflux.

G. Dorn, D. Sens, P. Halushka, 1987, Circulation research.

Thromboxane A2 and prostacyclin production by lipopolysaccharide-stimulated peritoneal macrophages.

P. Halushka, J. Cook, W. C. Wise, 1981, Journal of the Reticuloendothelial Society.

Vasopressin stimulates thromboxane synthesis in the toad urinary bladder: effects of imidazole.

P. Halushka, D. Knapp, R. Burch, 1979, The Journal of pharmacology and experimental therapeutics.

7-[(1R,2S,3S,5R)-6,6-dimethyl-3-(4- iodobenzenesulfonylamino)bicyclo[3.1.1]hept-2-yl]-5(Z)-heptenoic acid: a novel high-affinity radiolabeled antagonist for platelet thromboxane A2/prostaglandin H2 receptors.

P. Halushka, T. Morinelli, N. Hamanaka, 1992, The Journal of pharmacology and experimental therapeutics.

Differential effect of pH on thromboxane A2/prostaglandin H2 receptor agonist and antagonist binding in human platelets.

E. Hazard, P. Halushka, T. Morinelli, 1991, The Journal of biological chemistry.

Arachidonic Acid Metabolism in Endotoxemia and Sepsis: Therapeutic Approaches

P. Halushka, J. Cook, E. J. Li, 1993 .

Beneficial effects of UK 37248, a thromboxane synthetase inhibitor, in experimental endotoxic shock in the rat.

P. Halushka, J. Cook, Wise Wc, 1983, British journal of clinical pharmacology.

Amlodipine Reduces Blood Pressure and Hadache Fquency in Cocaine-Dependent Outpatients

P. Halushka, R. Malcolm, D. Yeager, 2002, Journal of psychoactive drugs.

Bartter's syndrome: urinary prostaglandin E-like material and kallikrein; indomethacin effects.

P. Halushka, H. Margolius, H. Wohltmann, 1977, Annals of internal medicine.

Sulindac does not preserve renal prostacyclin synthesis during endotoxemia.

P. Halushka, J. Cook, L. Olanoff, 1985, Prostaglandins.

Vasopressin-stimulated water flow is decreased by thromboxane synthesis inhibition or antagonism.

P. Halushka, D. Knapp, R. Burch, 1980, The American journal of physiology.

Gi proteins regulate lipopolysaccharide and Staphylococcus aureus induced cytokine production but not (1--> 3)-beta-D-glucan induced cytokine suppression.

David L. Williams, B. Zingarelli, G. Teti, 2006, Frontiers in bioscience : a journal and virtual library.

Lipopolysaccharide- and gram-positive bacteria-induced cellular inflammatory responses: role of heterotrimeric Galpha(i) proteins.

L. Birnbaumer, B. Zingarelli, G. Teti, 2005, American journal of physiology. Cell physiology.

Implication of G i proteins and Src tyrosine kinases in endotoxin-induced signal transduction events and mediator production

F. Squadrito, M. Ferlito, P. Halushka, 2002, Journal of endotoxin research.

Effect of cross‐tolerance between endotoxin and TNF‐α or IL‐1β on cellular signaling and mediator production

F. Squadrito, M. Ferlito, P. Halushka, 2001, Journal of Leukocyte Biology.

Effects of oleic acid on pulmonary capillary leak and thromboxanes.

K. Spicer, P. Halushka, H. Reines, 1984, The Journal of surgical research.

Increased platelet thromboxane A2/prostaglandin H2 receptors in patients with acute myocardial infarction.

G. Dorn, P. Halushka, D. Mais, 1990, Circulation.

Mediators of the secretory response to kinins

P. Halushka, H. Margolius, J. Spayne, 1984, British journal of pharmacology.

Hydrogen bond interactions of a series of N-substituted TXA2 receptor antagonists.

P. Halushka, G. P. Meier, Dawn Taylor, 2003, European journal of medicinal chemistry.

Thromboxane A2 Receptor Density Increases during Chronic Exposure to Thromboxane A2 Receptor Antagonists after Porcine Carotid Bypass

J. Boggs, P. Halushka, T. Brothers, 1995 .

Extraction of thromboxane B2 from urine using an immobilized antibody column for subsequent analysis by gas chromatography-mass spectrometry.

I. Blair, P. Halushka, D. Knapp, 1987, Prostaglandins.

Endotoxin tolerance is associated with decreased prostaglandin H synthases-1 and -2.

P. Halushka, J. Cook, J. Geisel, 1994, The American journal of physiology.

Exosomes from Endothelial Progenitor Cells Improve the Outcome of a Murine Model of Sepsis.

Pengfei Li, A. Goodwin, P. Halushka, 2018, Molecular therapy : the journal of the American Society of Gene Therapy.

Increased thromboxane level in experimental spinal cord injury

E. Hogan, P. Halushka, C. Hsu, 1986, Journal of the Neurological Sciences.

Prostaglandins, thromboxanes, and platelet function.

P. Halushka, D. Knapp, L. Grimm, 1979, Current topics in hematology.

Vasopressin stimulates thromboxane synthesis in the toad urinary bladder: effects of thromboxane synthesis inhibition.

P. Halushka, D. Knapp, R. Burch, 1980, Advances in prostaglandin and thromboxane research.

Effect of the LTD4 receptor antagonist LY203647 on endotoxic shock sequelae in the rat.

P. Halushka, J. Cook, S. Ashton, 1991, European journal of pharmacology.

Different pharmacologic activities for 13-azapinane thromboxane A2 analogs in platelets and blood vessels.

P. Halushka, D. Mais, D. DeHoll, 1988, European journal of pharmacology.

The potential role of thromboxane and prostacyclin in endotoxic and septic shock.

P. Halushka, J. Cook, H. Reines, 1984, The American journal of emergency medicine.

Agonists γ Proliferator Activation Receptor-and 2 Mice by Prostaglandin J lpr MRL / Inhibition of Mesangial Cell Nitric Oxide in

J. Morrow, G. Gilkeson, J. Oates, 2000 .

Regulation by Dexamethasone

W. Sessa, P. Halushka, A. Nasjletti, 2005 .

Characterization of the vascular thromboxane A2/prostaglandin endoperoxide receptor in rabbit aorta. Regulation by dexamethasone.

W. Sessa, P. Halushka, A. Nasjletti, 1990, Circulation research.

Endotoxin-induced arachidonic acid metabolism requires de novo protein synthesis and protein kinase C activation.

P. Halushka, J. Cook, J. Geisel, 1991, Biochimica et biophysica acta.

Indomethacin-responsive hypercalcemia in a patient with renal-cell adenocarcinoma.

V. Devita, H. Brereton, P. Halushka, 1974, The New England journal of medicine.

Pharmacologic characterization of human and canine thromboxane A2/prostaglandin H2 receptors in platelets and blood vessels: evidence for different receptors.

P. Halushka, D. Knapp, N. Hamanaka, 1985, The Journal of pharmacology and experimental therapeutics.

An institution-wide faculty mentoring program at an academic health center with 6-year prospective outcome data

K. Brady, H. Bonilha, G. Silvestri, 2019, Journal of Clinical and Translational Science.

Altered responses to modulators of guanine nucleotide binding protein activity in endotoxin tolerance.

P. Halushka, J. Cook, K. Coffee, 1990, Biochimica et biophysica acta.

Differential alteration of lipoxygenase and cyclooxygenase metabolism by rat peritoneal macrophages induced by endotoxin tolerance.

P. Halushka, J. Cook, W. C. Wise, 1986, Prostaglandins.

CONTRIBUTION OF PROSTAGLANDINS TO THE BIOLOGICAL ACTIVITY OF DIALYZABLE LEUKOCYTE EXTRACTS CONTAINING TRANSFER FACTOR ACTIVITY

G. B. Wilson, P. Halushka, M. Berkaw, 1979 .

Experimental endotoxemia in the rat: efficacy of prostacyclin or the prostacyclin analog iloprost.

P. Halushka, J. Cook, E. Smith, 1985, Circulatory shock.

Alterations in Gc levels and complexing in septic shock.

W. M. Lee, P. Halushka, J. Cook, 1989, Circulatory shock.

Thromboxane A2/prostaglandin H2 receptors in streptozotocin-induced diabetes: effects of insulin therapy in the rat.

A. Jaffa, P. Halushka, G. Tempel, 1993, Prostaglandins.

The effects of alpha adrenergic agents on human platelet aggregation.

P. Halushka, C. Hsu, D. Knapp, 1979, The Journal of pharmacology and experimental therapeutics.

Protective effects of thromboxane synthetase inhibitors in rats in endotoxic shock.

P. Halushka, J. Cook, D. Knapp, 1980, Circulation research.

Mononuclear cell modulation of connective tissue function: suppression of fibroblast growth by stimulation of endogenous prostaglandin production.

J. Korn, P. Halushka, E. Leroy, 1980, The Journal of clinical investigation.

Thromboxane A2 receptor blockade improves renal function and histopathology in the post-obstructive kidney.

M. Sens, P. Halushka, D. Ploth, 1994, Kidney International.

Characterization of rat glomerular thromboxane A2 receptors: comparison to rat platelets.

P. Halushka, C. Wilcox, W. Folger, 1992, European journal of pharmacology.

Radioiododestannylation. Convenient synthesis of a high affinity thromboxane A2/prostaglandin H2 receptor antagonist

P. Halushka, T. Morinelli, N. Hamanaka, 1991 .

BIOSYNTHESIS OF PROSTAGLANDIN E BY RAT SUPERIOR CERVICAL GANGLIA 1

P. Halushka, J. G. Webb, D. Saelens, 1978, Journal of neurochemistry.

Lead and Cadmium Effect on Host Defense Mechanisms and Toxic Interactions with Bacterial Endotoxin

P. Halushka, J. Cook, Wise Wc, 1984 .

Effect of a LTD4 receptor antagonist in porcine septic shock.

P. Halushka, J. Cook, E. Smith, 1991, Eicosanoids.

Macrophage eicosanoid formation is stimulated by platelet arachidonic acid and prostaglandin endoperoxide transfer.

P. Halushka, J. Cook, E. Smith, 1987, Biochimica et biophysica acta.

Beneficial effects of ibuprofen in oleic acid induced lung injury.

P. Halushka, T. Fuhrman, H. Reines, 1987, The Journal of surgical research.

Alterations in extracellular calcium concentration differentially influence prostaglandin and thromboxane synthesis in epithelial cells from the toad urinary bladder.

P. Halushka, R. Burch, 1984, Archives of biochemistry and biophysics.

16 Lead and Cadmium Effeet on Host Defense Meehanisms and Toxie Interaetions with Baeterial Endotoxin

P. Halushka, J. Cook, Wise Wc, 1984 .

Vasopressin stimulates thromboxane synthesis in isolated hamster hepatocytes: relation to hepatocyte calcium content.

P. Halushka, D. Jollow, R. Burch, 1983, Prostaglandins.

Effect of ibuprofen, a fatty acid cyclooxygenase inhibitor, on murine lupus.

P. Halushka, V. Kelley, S. Izui, 1982, Clinical immunology and immunopathology.

THE ROLE OF THROMBOXANE A, IN THE CONTROL OF VASOPRESSIN‐STIMULATED WATER FLOW IN THE TOAD URINARY BLADDER

P. Halushka, R. Burch, 1981 .

Beneficial effects of a leukotriene antagonist on endotoxin-induced acute hemodynamic alterations.

P. Halushka, J. Cook, G. Tempel, 1987, Circulatory shock.

Essential fatty acid-deficient rats are resistant to oleic acid-induced pulmonary injury.

K. Spicer, P. Halushka, J. Cook, 1989, Journal of applied physiology.

Improvement in Organ Blood Flow by Inhibition of Thromboxane Synthetase During Experimental Endotoxic Shock in the Rat

P. Halushka, J. Cook, G. Tempel, 1986, Journal of cardiovascular pharmacology.

Binding of thromboxane A2/prostaglandin H2 agonists to human platelets

P. Halushka, P. Kochel, D. Mais, 1987, British journal of pharmacology.

Urinary thromboxane B2 and thromboxane receptors in bladder cancer: opportunity for detection and monitoring.

D. Watson, P. Halushka, O. Moussa, 2011, Prostaglandins & other lipid mediators.

The affinities of prostaglandin H2 and thromboxane A2 for their receptor are similar in washed human platelets.

J. Gillard, P. Halushka, T. Morinelli, 1988, Biochemical and biophysical research communications.

Ibuprofen improves survival from endotoxic shock in the rat.

P. Halushka, J. Cook, Wise Wc, 1980, Journal of Pharmacology and Experimental Therapeutics.

Elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency.

P. Halushka, J. Cook, W. C. Wise, 1980, The Journal of clinical investigation.

Pathogenesis of Atherosclerosis in Diabetes Mellitus

P. Halushka, M. Lopes-Virella, J. Colwell, 1981, Diabetes Care.

Synthesis of 10,10-difluorothromboxane A2, a potent and chemically stable thromboxane agonist

P. Halushka, Chien-Kuang Chen, T. Morinelli, 1989 .

Prostaglandin-independent inhibition of calcium transport by nonsteroidal anti-inflammatory drugs: differential effects of carboxylic acids and piroxicam.

P. Halushka, R. Burch, W. C. Wise, 1983, The Journal of pharmacology and experimental therapeutics.

Thromboxane-A(2)/prostaglandin-H(2) receptors Characterization and antagonism.

P. Halushka, T. Morinelli, P. V. Halushka, 1991, Trends in cardiovascular medicine.

Thromboxane-A(2)/prostaglandin-H(2) receptors Characterization and antagonism.

P. Halushka, T. Morinelli, 1991, Trends in cardiovascular medicine.

Subcellular localization of a thromboxane A2/prostaglandin H2 receptor antagonist binding site in human platelets.

P. Halushka, D. Mais, S. Pepkowitz, 1988, Biochemical pharmacology.

Does tetrahydroparaveroline contribute to the cardiovascular actions of dopamine?

P. Halushka, P. Hoffmann, 1968, Biochemical pharmacology.

Novel role of thromboxane receptors beta isoform in bladder cancer pathogenesis.

E. Garrett-Mayer, D. Watson, P. Halushka, 2008, Cancer research.

Arachidonic acid turnover in peritoneal macrophages is altered in endotoxin-tolerant rats.

P. Halushka, J. Cook, W. C. Wise, 1989, Biochimica et biophysica acta.

Inhibition of thromboxane synthase activity modulates bladder cancer cell responses to chemotherapeutic agents

D. Watson, P. Halushka, O. Moussa, 2008, Oncogene.

Total synthesis of (+)-10,10-difluorothromboxane A2 and its 9,11 and 15 stereoisomers

P. Halushka, Ramiya H. Premchandran, J. Fried, 1992 .

Novel synthesis and biochemical properties of an [125I]-labeled photoaffinity probe for thromboxane A2/prostaglandin H2 receptors.

P. Halushka, T. Morinelli, N. Hamanaka, 1991, Journal of medicinal chemistry.

Furosemide increases urine 6-keto-prostaglandin F1 alpha. Relation to natriuresis, vasodilation, and renin release.

P. Halushka, C. Loadholt, T. Wilson, 1982, Hypertension.

Synthesis of thromboxane receptor antagonists with the potential to radiolabel with 125I

P. Halushka, D. Knapp, N. Hamanaka, 1984 .

Total Synthesis of (+)-10,10-Difluorothromboxane A2 and Its 9,11 and 15 Stereoisomers.

P. Halushka, Ramiya H. Premchandran, J. Fried, 2010 .

Thromboxane A 2 and prostaglandin endoperoxide receptors in platelets and vascular smooth muscle

P. Halushka, D. Knapp, D. Mais, 2005 .

Thromboxane A2 and prostaglandin endoperoxide receptors in platelets and vascular smooth muscle.

P. Halushka, D. Knapp, D. Mais, 1985, Circulation.

The role of miRNAs in cardiovascular disease risk factors.

A. Goodwin, P. Halushka, J. Cook, 2016, Atherosclerosis.

Suppression of Fli-1 protects against pericyte loss and cognitive deficits in Alzheimer's disease.

Pengfei Li, A. Goodwin, P. Halushka, 2022, Molecular therapy : the journal of the American Society of Gene Therapy.

A Stromal Cell-Derived Factor 1α Analogue Improves Endothelial Cell Function in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome

B. Zingarelli, A. Goodwin, P. Halushka, 2016, Molecular medicine.

Plasma levels of microRNA are altered with the development of shock in human sepsis: an observational study

B. Wolf, A. Goodwin, P. Halushka, 2015, Critical Care.

Differential regulation of lipopolysaccharide and Gram‐positive bacteria induced cytokine and chemokine production in macrophages by Gαi proteins

L. Birnbaumer, David L. Williams, B. Zingarelli, 2007 .

Endotoxin-induced procoagulant activity, eicosanoid synthesis, and tumor necrosis factor production by rat peritoneal macrophages: effect of endotoxin tolerance and glucan.

P. Halushka, J. Cook, J. Moore, 1990, Circulatory shock.

Childhood familial and racial differences in physiologic and biochemical factors related to hypertension.

S. Schuman, P. Halushka, H. Margolius, 1983, Hypertension.

45Ca fluxes in isolated toad bladder epithelial cells: effects of agents which alter water or sodium transport.

P. Halushka, R. Burch, 1983, The Journal of pharmacology and experimental therapeutics.

Arachidonic acid stimulates short-circuit current in the isolated toad urinary bladder.

M. Auber, P. Halushka, A. Levanho, 1980, The Journal of pharmacology and experimental therapeutics.

THE PHOSPHATIDYLINOSITOL 3 KINASE PATHWAY REGULATES TOLERANCE TO LIPOPOLYSACCHARIDE AND PRIMING RESPONSES TO STAPHYLOCOCCUS AUREUS AND LIPOPOLYSACCHARIDE

B. Zingarelli, G. Teti, P. Halushka, 2006, Shock.

Increased platelet thromboxane A2/prostaglandin H2 receptors in patients with pregnancy induced hypertension.

P. Halushka, J. Lieberman, I. Nathan, 1993, Thrombosis research.

Binding of a thromboxane A2/prostaglandin H2 receptor antagonist to washed human platelets.

P. Halushka, P. Kochel, D. Mais, 1985, The Journal of pharmacology and experimental therapeutics.

Solubilization of a thromboxane A2/prostaglandin H2 antagonist binding site from human platelets.

P. Halushka, D. Mais, R. Burch, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Increased synthesis of prostaglandin-E-like material by platelets from patients with diabetes mellitus.

P. Halushka, J. Colwell, D. Lurie, 1977, The New England journal of medicine.

Increased Platelet Arachidonic Acid Metabolism in Diabetes Mellitus

R. Mayfield, P. Halushka, J. Colwell, 1981, Diabetes.

Staphylococcus aureus and Lipopolysaccharide Induce Homologous Tolerance but Heterologous Priming: Role of Interferon-&ggr;

G. Teti, P. Halushka, J. Cook, 2004, Shock.

Signal transduction events in Chinese hamster ovary cells expressing human CD14; effect of endotoxin desensitization.

F. Squadrito, M. Ferlito, P. Halushka, 2001, Shock.

Acute Effects of Alpha‐Methyldopa on Mean Blood Pressure and Plasma Renin Activity

P. Halushka, H. Keiser, 1974, Circulation research.

Fli‐1 transcription factor regulates the expression of caspase‐1 in lung pericytes

Pengfei Li, A. Goodwin, P. Halushka, 2019, Molecular immunology.

Thromboxane A(2) receptors: where have you gone?

P. Halushka, 2000, Prostaglandins & other lipid mediators.

Coupling of thromboxane A2 receptor isoforms to Galpha13: effects on ligand binding and signalling.

P. Halushka, T. Gettys, M. Garnovskaya, 1999, Biochimica et biophysica acta.

Mechanism of platelet inhibition by nitric oxide: in vivo phosphorylation of thromboxane receptor by cyclic GMP-dependent protein kinase.

T. Lincoln, P. Halushka, M. Mendelsohn, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Expression, Characterization, and Purification of C-terminally Hexahistidine-tagged Thromboxane A2 Receptors*

K. Schey, P. Halushka, S. Pawate, 1998, The Journal of Biological Chemistry.

Characterization of the cloned HEL cell thromboxane A2 receptor: evidence that the affinity state can be altered by G alpha 13 and G alpha q.

P. Halushka, T. Gettys, T. Morinelli, 1996, The Journal of pharmacology and experimental therapeutics.

The Faculty Costs to Educate a Biomedical Sciences Graduate Student

E. Garrett-Mayer, P. Halushka, Adams J Smolka, 2015, CBE - Life Sciences Education.

Thromboxane and prostacyclin in disease: a review.

C. Dollery, P. Halushka, J. Macdermot, 1983, The Quarterly journal of medicine.

Interaction of eicosanoids and macrophages during inflammatory responses

E. F. Smith, P. Halushka, J. Cook, 1984, Survey of immunologic research.

Castration reduces platelet thromboxane A2 receptor density and aggregability.

P. Halushka, A. A. Ajayi, 2005, QJM : monthly journal of the Association of Physicians.

Testosterone increases thromboxane A2 receptor density and responsiveness in rat aortas and platelets.

P. Halushka, T. Morinelli, K. Matsuda, 1994, The American journal of physiology.

PLASMA THROMBOXANE CONCENTRATIONS ARE RAISED IN PATIENTS DYING WITH SEPTIC SHOCK

P. Halushka, J. Cook, Wise Wc, 1982, The Lancet.

Hydrodynamic properties of a thromboxane A2/prostaglandin H2 antagonist binding site solubilized from human platelets.

P. Halushka, D. Mais, S. Pepkowitz, 1985, Biochemical and biophysical research communications.

Suppression of Cox-2 and TNF-alpha mRNA in endotoxin tolerance: effect of cycloheximide, antinomycin D, and okadaic acid.

M. Ferlito, P. Halushka, J. Cook, 2000, Shock.

Binding of a thromboxane A2/prostaglandin H2 receptor antagonist to guinea-pig platelets.

P. Halushka, D. Mais, M. Garvin, 1986, European journal of pharmacology.

Role of calcium ions in kinin‐induced chloride secretion

P. Halushka, H. Margolius, J. Spayne, 1984, British journal of pharmacology.

Thromboxane and prostacyclin production during septic shock.

P. Halushka, J. Cook, W. C. Wise, 1982, Advances in shock research.

Why are some individuals resistant to the cardioprotective effects of aspirin? Could it be thromboxane A2?

M. Halushka, P. Halushka, 2002, Circulation.

Fli-1 Governs Pericyte Dysfunction in a Murine Model of Sepsis

Pengfei Li, B. Zingarelli, A. Goodwin, 2018, The Journal of infectious diseases.

Prognostic and functional significance of thromboxane synthase gene overexpression in invasive bladder cancer.

D. Sinha, D. Watson, P. Halushka, 2005, Cancer research.

Prognostic and functional significance of thromboxane synthase gene overexpression in invasive bladder cancer.

D. Sinha, D. Watson, P. Halushka, 2005, Cancer research.

Regulation of the Tumor Suppressor FOXO3 by the Thromboxane-A2 Receptors in Urothelial Cancer

E. Garrett-Mayer, P. Halushka, O. Moussa, 2014, PloS one.

Homologous desensitization of human platelet thromboxane A2/prostaglandin H2 receptors.

P. Halushka, M. Ullian, A. Okwu, 1992, The Journal of pharmacology and experimental therapeutics.

Platelet and vascular thromboxane A2/prostaglandin H2 receptors. Evidence for different subclasses in the rat.

P. Halushka, D. Mais, A. Masuda, 1991, Biochemical pharmacology.

Difluorothromboxane A2 and stereoisomers: stable derivatives of thromboxane A2 with differential effects on platelets and blood vessels.

P. Halushka, T. Morinelli, J. Fried, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Endotoxin-induced desensitization of THP-1 cells is not associated with altered G protein binding or content

M. Makhlouf, P. Halushka, J. Cook, 1997 .

Effect of leukotriene receptor antagonists on vascular permeability during endotoxic shock.

K. Spicer, P. Halushka, J. Cook, 1990, Circulatory shock.

Endotoxin tolerance is associated with altered GTP-binding protein function.

P. Halushka, J. Cook, G. Tempel, 1992, Journal of applied physiology.

Endotoxin Tolerance Differentially Alters Hemodynamic Responses to a Thromboxane A2 Mimetic and Phenylephrine

P. Halushka, J. Cook, G. Tempel, 1991, Journal of cardiovascular pharmacology.

INCREASED NITRIC OXIDE SYNTHESIS DURING THE DEVELOPMENT OF ENDOTOXIN TOLERANCE

B. Zingarelli, A. Caputi, P. Halushka, 1995, Shock.

Reorientation of macrophage mediator production in endotoxin tolerance.

B. Zingarelli, A. Caputi, P. Halushka, 1995, Progress in clinical and biological research.

Testosterone treatment enhances thromboxane A2 mimetic induced coronary artery vasoconstriction in guinea pigs

K. Schrör, P. Halushka, T. Morinelli, 1994, European journal of clinical investigation.

Exosomes from endothelial progenitor cells improve outcomes of the lipopolysaccharide-induced acute lung injury

Pengfei Li, B. Zingarelli, A. Goodwin, 2019, Critical Care.

Increased Myocardial Release of Prostacyclin in Dogs with Heart Failure

P. Halushka, W. Newman, M. Frankis, 1983, Journal of cardiovascular pharmacology.

Binding of a thromboxane A2/prostaglandin H2 agonist [3H]U46619 to washed human platelets.

P. Halushka, D. Mais, N. Liel, 1987, Prostaglandins.

Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in splenocytes by Gαi proteins

L. Birnbaumer, David L. Williams, B. Zingarelli, 2006 .

Implications for thromboxane A2 in the pathogenesis of endotoxic shock.

P. Halushka, J. Cook, W. C. Wise, 1981, Advances in shock research.

Beneficial effects of a 5-lipoxygenase inhibitor in endotoxic shock in the rat.

P. Halushka, J. Cook, G. Tempel, 1988, The Journal of pharmacology and experimental therapeutics.

Protective effect of a selective leukotriene antagonist in endotoxemia in the rat.

P. Halushka, J. Cook, W. C. Wise, 1985, The Journal of pharmacology and experimental therapeutics.

Desensitization of platelet thromboxane A2/prostaglandin H2 receptors by the mimetic U46619.

P. Halushka, D. Mais, N. Liel, 1988, Journal of Pharmacology and Experimental Therapeutics.

Photoaffinity receptor antagonist for human platelet thromboxane A2/prostaglandin H2 receptors.

P. Halushka, D. Mais, N. Liel, 1990, Biochemical pharmacology.

PLATELETS AND VASCULAR OCCLUSION Thromboxane A 2 and prostaglandin endoperoxide receptors in platelets and vascular smooth muscle

P. Halushka, D. Knapp, D. Saussy, 2005 .

Histochemical and ultrastructural studies in fibrodysplasia ossificans progressiva (myositis ossificans progressiva).

S. Spicer, R. Miller, P. Halushka, 1977, The American journal of pathology.

Attenuation of Postganglionic Sympathetic Nerve Activity by L‐Dopa

P. Halushka, T. Whitsett, L. Goldberg, 1970, Circulation research.

Scientific retreats with ‘speed dating’: networking to stimulate new interdisciplinary translational research collaborations and team science

Jihad S Obeid, Anthony J Alberg, K. Brady, 2016, Journal of Investigative Medicine.

Protective Effects of trans‐13-APT, a Thromboxane Receptor Antagonist, in Endotoxemia

P. Halushka, J. Cook, D. Knapp, 1985, Journal of cardiovascular pharmacology.

Binding of an 125I-labeled thromboxane A2/prostaglandin H2 receptor antagonist to washed canine platelets.

P. Halushka, P. Kochel, D. Mais, 1985, Molecular pharmacology.

ADH or theophylline-induced changes in intracellular free and membrane-bound calcium.

P. Halushka, R. Burch, 1984, The American journal of physiology.

Oleic acid induces pulmonary injury independent of eicosanoids in the isolated, perfused rabbit lung.

P. Halushka, J. Cook, S. Katz, 1987, Circulatory shock.

beta-Arrestin 2: a Negative Regulator of Inflammatory Responses in Polymorphonuclear Leukocytes.

L. Luttrell, B. Zingarelli, P. Halushka, 2008, International journal of clinical and experimental medicine.

Circulating extracellular vesicles are associated with the clinical outcomes of sepsis

B. Zingarelli, A. Goodwin, P. Halushka, 2023, Frontiers in Immunology.

Alcohol addiction and tetrahydropapaveroline.

P. Halushka, M. J. Walsh, V. E. Davis, 1970, Science.

PLATELET FUNCTION IN DIABETES MELLITUS

P. Halushka, J. Colwell, Perry V. Halushka, 1980, British journal of haematology.

Thromboxane A2/Prostaglandin H2 Receptors: A Growing Family of Receptor Subtypes

P. Halushka, T. Morinelli, D. Mais, 1991 .

Thromboxane A2 receptors are influenced by cell density in cultured rat aortic smooth muscle cells.

P. Halushka, A. Masuda, 1991, Life sciences.

Human erythroleukemia cells express functional thromboxane A2/prostaglandin H2 receptors.

P. Halushka, C. Carr, D. Mais, 1989, The Journal of pharmacology and experimental therapeutics.

Photoaffinity labelling of the human platelet thromboxane A2/prostaglandin H2 receptor.

C. Yoakim, J. Rokach, J. Gillard, 1989, Biochimica et biophysica acta.

Further studies on the effects of epimers of thromboxane A2 antagonists on platelets and veins.

P. Halushka, N. Hamanaka, D. Mais, 1985, European journal of pharmacology.

Application of Deacetylated Poly-N-Acetyl Glucosamine Nanoparticles for the Delivery of miR-126 for the Treatment of Cecal Ligation and Puncture-Induced Sepsis

A. Goodwin, P. Halushka, J. Cook, 2018, Inflammation.

Circulating MiRNA 887 is Differentially Expressed in ARDS and Modulates Endothelial Function.

Pengfei Li, A. Goodwin, P. Halushka, 2020, American journal of physiology. Lung cellular and molecular physiology.

Protective effects of aspirin in endotoxic shock.

P. Halushka, J. Cook, W. C. Wise, 1981, The Journal of pharmacology and experimental therapeutics.

An institution-wide faculty mentoring program at an academic health center with 6-year prospective outcome data – ADDENDUM

K. Brady, H. Bonilha, G. Silvestri, 2020, Journal of Clinical and Translational Science.

Beneficial Effect of a CXCR4 Agonist in Murine Models of Systemic Inflammation

D. Wong, P. Halushka, J. Cook, 2012, Inflammation.

Toll-like receptor 4 coupled GI protein signaling pathways regulate extracellular signal-regulated kinase phosphorylation and AP-1 activation independent of NFkappaB activation.

P. Halushka, J. Cook, G. Tempel, 2004, Shock.

Toll-like Receptor-Induced Inflammatory Cytokines are Suppressed by Gain of Function or Overexpression of Gαi2 Protein

R. Neubig, Pengfei Li, B. Zingarelli, 2012, Inflammation.

Combined treatment with a CXCL12 analogue and antibiotics improves survival and neutrophil recruitment and function in murine sepsis

B. Zingarelli, P. Halushka, J. Cook, 2015, Immunology.

Arachidonic acid metabolism in endotoxin tolerance.

P. Halushka, J. Cook, W. C. Wise, 1983, Advances in shock research.

A Message from the Scientific Program Committee Chairperson: Submission of Abstracts for the 1995 Annual Meeting

P. Halushka, 1994 .

The Gordon Wilson Lecture. Regulation of thromboxane A2 receptors by testosterone: implications for steroid abuse and cardiovascular disease.

P. Halushka, K. Matsuda, A. Masuda, 1994, Transactions of the American Clinical and Climatological Association.

Insulin and arachidonic acid metabolism in diabetes mellitus.

R. Mayfield, P. Halushka, J. Colwell, 1985, Metabolism: clinical and experimental.

Modification on ligand binding to TXA2/PGH2 receptors by diethylpyrocarbonate.

K. Schrör, P. Halushka, K. Davis-Bruno, 1997, Advances in Experimental Medicine and Biology.

Vasopressin stimulates prostaglandin and thromboxane synthesis in toad bladder epithelial cells.

P. Halushka, R. Burch, 1982, The American journal of physiology.

Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production.

P. Halushka, J. Cook, W. C. Wise, 1983, The Journal of pharmacology and experimental therapeutics.

Decrease in vascular TxA2 receptors in a subgroup of rabbits unresponsive to a TxA2 mimetic.

W. Campbell, P. Halushka, S. Pfister, 1994, The American journal of physiology.

Androgen regulation of thromboxane A2/prostaglandin H2 receptor expression in human erythroleukemia cells.

E. Duzic, P. Halushka, K. Matsuda, 1993, The American journal of physiology.

Differential effects of 15‐deoxy‐Δ12,14‐prostaglandin J2 and a peroxisome proliferator‐activated receptor γ agonist on macrophage activation

R. Bond, G. Gilkeson, P. Halushka, 2001, Journal of Leukocyte Biology.

BENEFICIALEFFECTSOFUK 37248, A THROMBOXANE SYNTHETASEINHIBITOR, INEXPERIMENTAL ENDOTOXIC SHOCK INTHERAT

P. Halushka, J. Cook, W. Curtiswise, 1983 .

Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation.

R. Bond, G. Gilkeson, P. Halushka, 2001, Journal of leukocyte biology.

Toward individualized analgesic therapy: Functional cyclooxygenase 1 and 2 haplotypes

M. Halushka, P. Halushka, 2006, Clinical pharmacology and therapeutics.

Application of Deacetylated Poly-N-Acetyl Glucosamine Nanoparticles for the Delivery of miR-126 for the Treatment of Cecal Ligation and Puncture-Induced Sepsis

A. Goodwin, P. Halushka, J. Cook, 2018, Inflammation.

Kinin effects on chloride secretion do not require eicosanoid synthesis

D. Kessel, P. Halushka, A. Cuthbert, 1984, British journal of pharmacology.

Ibuprofen, methylprednisolone, and gentamicin as conjoint therapy in septic shock.

P. Halushka, J. Cook, W. C. Wise, 1985, Circulatory shock.

Decrease in agonist affinity for human platelet thromboxane A2/prostaglandin H2 receptors induced by a platelet-derived supernatant.

G. Dorn, P. Halushka, P. Kochel, 1987, Biochemical pharmacology.

Photoaffinity labelling of a thromboxane A2/prostaglandin H2 antagonist binding site in human platelets.

P. Halushka, D. Knapp, D. Mais, 1986, Biochemical and biophysical research communications.

Thromboxane A 2 Receptors: Characterization and Regulation

P. Halushka, T. Morinelli, D. Mais, 1993 .

Potentiation of PDGF-induced growth responses in coronary artery smooth muscle cells by thromboxane.

T. Grosser, K. Schrör, P. Halushka, 1995, Agents and actions. Supplements.

A novel approach for the study of thromboxane A2 and prostaglandin H2 receptors using an 125I-labeled ligand.

C. Dollery, I. Blair, P. Halushka, 1985, Biochemical pharmacology.

Identification of a putative thromboxane A2/prostaglandin H2 receptor in human platelet membranes.

P. Halushka, D. Mais, R. Burch, 1986, The Journal of biological chemistry.

Thromboxane and prostacyclin receptors.

P. Halushka, T. Morinelli, D. Mais, 1989, Progress in clinical and biological research.

Effect of LTB4 receptor antagonists in endotoxic shock in the rat.

P. Halushka, J. Cook, W. Jackson, 1991, Circulatory shock.

Peroxiredoxin VI oxidation in cerebrospinal fluid correlates with traumatic brain injury outcome.

E. Jauch, D. Townsend, K. Tew, 2014, Free radical biology & medicine.

Peroxiredoxin VI Oxidation in Cerebrospinal Fluid Correlates with TBI Outcome

E. Jauch, D. Townsend, K. Tew, 2014 .

Pharmacology of a new cyclic nucleotide phosphodiesterase type 4 inhibitor, V11294.

D. Cavalla, P. Halushka, C. Page, 2003, Pulmonary pharmacology & therapeutics.

Hemodynamic effects of leukotriene (LT) D4 and a LTD4 receptor antagonist in the pig.

P. Halushka, J. Cook, E. Smith, 1990, Eicosanoids.

Bartter's Syndrome: Urinary Prostaglandin E-like Material and Kallikrein; Indomethacin Effects

P. Halushka, H. Margolius, H. Wohltmann, 1977 .

Molecular pharmacology and therapeutic potential of thromboxane A2 receptor antagonists

P. Halushka, K. Davis-Bruno, 1994 .

Effect of cross-tolerance between endotoxin and TNF-alpha or IL-1beta on cellular signaling and mediator production.

F. Squadrito, M. Ferlito, P. Halushka, 2001, Journal of leukocyte biology.

lncRNA Neat1 regulates neuronal dysfunction post sepsis via stabilization of hemoglobin subunit beta.

Shinichi Nakagawa, Pengfei Li, Jiliang Zhou, 2022, Molecular therapy : the journal of the American Society of Gene Therapy.

Beneficial Effect of a CXCR4 Agonist in Murine Models of Systemic Inflammation

D. Wong, P. Halushka, J. Cook, 2011, Inflammation.

Tolerance to LPS decreases macrophage G protein content.

M. Makhlouf, P. Halushka, J. Cook, 1999, Shock.

Endotoxin tolerance alters macrophage membrane regulatory G proteins.

B. Zingarelli, M. Makhlouf, P. Halushka, 1998, Progress in clinical and biological research.

Involvement of G(i) proteins and Src tyrosine kinase in TNFalpha production induced by lipopolysaccharide, group B Streptococci and Staphylococcus aureus.

G. Teti, P. Halushka, J. Cook, 2003, Cytokine.

Selective Cyclooxygenase-2 Inhibitor Suppresses Renal Thromboxane Production but Not Proliferative Lesions in the MRL/lpr Murine Model of Lupus Nephritis

G. Gilkeson, J. Oates, P. Halushka, 2011, The American journal of the medical sciences.

Cyclooxygenase Products in Septic and Endotoxic Shock

P. Halushka, J. Cook, T. Wagner, 2019, Handbook of Mediators in Septic Shock.

Modulation of macrophage arachidonic acid metabolism: potential role in the susceptibility of rats to endotoxic shock.

P. Halushka, J. Cook, W. C. Wise, 1982, Circulatory shock.

Distribution and metabolism of dopamine in guinea‐pigs

P. Halushka, P. Hoffmann, P. V. Halushka, 1968, The Journal of pharmacy and pharmacology.

Lack of effect of glucocorticoids upon plasma thromboxane in patients in a state of shock.

P. Halushka, J. Cook, C. Loadholt, 1985, Surgery, gynecology & obstetrics.

ENDOTOXIN TOLERANCE: EFFECTS ON LETHALITY AND MACROPHAGE THROMBOXANE (B2) AND INTERLEUKIN 6 PRODUCTION

P. Halushka, J. Cook, Hong Chen, 1994, Shock.

The role of eicosanoids in mediating blood flow alterations in endotoxin shock.

P. Halushka, J. Cook, E. Smith, 1989, Progress in clinical and biological research.