H. Brade

发表

The significance of the hydrophilic backbone and the hydrophobic fatty acid regions of lipid A for macrophage binding and cytokine induction.

T. Kirikae, E. Rietschel, F. Schade, 1994, FEMS immunology and medical microbiology.

The Active Principle of Bacterial Lipopolysaccharides (Endotoxins) for Cytokine Induction

H. Brade, H. Loppnow, Flad Hd, 1993 .

Modulation of lipopolysaccharide-induced production of tumor necrosis factor, interleukin 1, and interleukin 6 by synthetic precursor Ia of lipid A.

J. Gerdes, H. Flad, Ming-Hai Wang, 1992, FEMS microbiology immunology.

Structure-activity relationships of bacterial lipopolysaccharides (endotoxins). Current and future aspects.

H. Brade, E. Rietschel, L. Brade, 1988, Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology.

[Lipopolysaccharides, endotoxins and O-antigens of gram-negative bacteria: chemical structure, biologic effect and serologic properties].

H. Brade, E. Rietschel, 1987, Infection.

Bacterial endotoxin: molecular relationships of structure to activity and function

T. Kirikae, F. D. Di Padova, A. Ulmer, 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Comparative functional characterization in vitro of heptosyltransferase I (WaaC) and II (WaaF) from Escherichia coli.

S. Gronow, H. Brade, W. Brabetz, 2000, European journal of biochemistry.

Isolation and structural analysis of oligosaccharide phosphates containing the complete carbohydrate chain of the lipopolysaccharide from Vibrio cholerae strain H11 (non-O1).

O. Holst, E. Vinogradov, H. Brade, 1994, European journal of biochemistry.

Preparation and structural analysis of oligosaccharide monophosphates obtained from the lipopolysaccharide of recombinant strains of Salmonella minnesota and Escherichia coli expressing the genus-specific epitope of Chlamydia lipopolysaccharide.

J. Thomas-Oates, O. Holst, H. Brade, 1994, European journal of biochemistry.

Construction of a Deep-rough Mutant of Burkholderia cepacia ATCC 25416 and Characterization of Its Chemical and Biological Properties*

S. Gronow, A. Blumenthal, B. Lindner, 2003, The Journal of Biological Chemistry.

Detection of lipopolysaccharide (LPS)-binding membrane proteins by immuno-coprecipitation with LPS and anti-LPS antibodies.

H. Flad, A. Ulmer, E. Rietschel, 1997, European journal of biochemistry.

Antibody Recognition of Chlamydia LPS: Structural Insights of Inherited Immune Responses

H. Brade, L. Brade, S. V. Evans, 2012 .

Chemical structure of the core region of Escherichia coli J-5 lipopolysaccharide.

O. Holst, H. Brade, S. Müller-Loennies, 1994, European journal of biochemistry.

The structures of the carbohydrate backbones of the lipopolysaccharides from Escherichia coli rough mutants F470 (R1 core type) and F576 (R2 core type).

J. Thomas-Oates, O. Holst, E. Vinogradov, 1999, European journal of biochemistry.

The chemical structure of bacterial endotoxin in relation to bioactivity.

T. Kirikae, O. Holst, A. Ulmer, 1993, Immunobiology.

Mapping the binding of synthetic disaccharides representing epitopes of chlamydial lipopolysaccharide to antibodies with NMR.

H. Brade, L. Brade, T. Peters, 2000, Biochemistry.

Deletion of the heptosyltransferase genes rfaC and rfaF in Escherichia coli K-12 results in an Re-type lipopolysaccharide with a high degree of 2-aminoethanol phosphate substitution.

O. Holst, H. Brade, W. Brabetz, 1997, European journal of biochemistry.

Chlamydia pneumoniae Multiply in Neutrophil Granulocytes and Delay Their Spontaneous Apoptosis1

Eresso Aga, W. Solbach, T. Laskay, 2004, The Journal of Immunology.

Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes.

C. MacKenzie, C. Brooks, H. Brade, 2008, Journal of molecular biology.

Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities.

E. Rietschel, C. Galanos, M. Freudenberg, 1985, European journal of biochemistry.

Endotoxin and lipid A stimulate proliferation of human T cells in the presence of autologous monocytes.

K. Toellner, M. Ernst, M. Duchrow, 1994, Journal of immunology.

A common NH53K mutation in the combining site of antibodies raised against chlamydial LPS glycoconjugates significantly increases avidity.

C. Brooks, H. Brade, L. Brade, 2011, Biochemistry.

Structural insights into parallel strategies for germline antibody recognition of lipopolysaccharide from Chlamydia.

C. Brooks, H. Brade, L. Brade, 2011, Glycobiology.

A monoclonal antibody with specificity for the genus Klebsiella binds to a common epitope located in the core region of Klebsiella lipopolysaccharide

H. Brade, L. Brade, R. Podschun, 2001, Journal of endotoxin research.

Structural Analysis of the Lipopolysaccharide fromChlamydia trachomatis Serotype L2*

O. Holst, B. Lindner, H. Brade, 1999, The Journal of Biological Chemistry.

Structural and serological characterisation of the O-antigenic polysaccharide of the lipopolysaccharide from Acinetobacter baumannii strain 24.

O. Holst, E. Vinogradov, H. Brade, 2003, Carbohydrate research.

Structural analysis of two oligosaccharide bisphosphates isolated from the lipopolysaccharide of a recombinant strain of Escherichia coli F515 (Re chemotype) expressing the genus-specific epitope of Chlamydia lipopolysaccharide.

J. Thomas-Oates, O. Holst, H. Brade, 1993, European journal of biochemistry.

Accumulation of bis(monoacylglycero)phosphate and gangliosides in mouse models of neuronal ceroid lipofuscinosis

P. Saftig, S. Walkley, M. Glatzel, 2008, Journal of neurochemistry.

Structural and serological characterisation of the O-antigenic polysaccharide of the lipopolysaccharide from Acinetobacter strain 96 (DNA group 11)

O. Holst, E. Vinogradov, H. Brade, 2001, Journal of endotoxin research.

Identification of a novel heptoglycan of alpha1-->2-linked D-glycero-D-manno-heptopyranose. Chemical and antigenic structure of lipopolysaccharides from Klebsiella pneumoniae ssp. pneumoniae rough strain R20 (O1-:K20-).

O. Holst, H. Brade, L. Brade, 1998, The Journal of biological chemistry.

Structural and serological characterisation of the O-specific polysaccharide from lipopolysaccharide of Acinetobacter calcoaceticus strain 7 (DNA group 1).

O. Holst, E. Vinogradov, H. Brade, 1997, European journal of biochemistry.

The structure of the O-specific polysaccharide of the lipopolysaccharide from Chromobacterium violaceum NCTC 9694.

O. Holst, E. Vinogradov, H. Brade, 1994, Carbohydrate research.

Structural investigation of the lipopolysaccharide from Proteus mirabilis R45 (Re-chemotype)

J. Thomas-Oates, O. Holst, E. Vinogradov, 1994 .

Isolation and structural analysis of the tetrasaccharide 3-deoxy-5-O-[3-O-(3-O-α-d-glucopyranosyl-l-glycero-α-d-manno-heptopyranosyl)-l-glycero-α-d-manno -heptopyranosyl]-d-manno-octulosonic acid from the core region of the lipopolysaccharide of Salmonella minnesota strain R5 (rough mutant chemotype

O. Holst, H. Brade, 1993 .

Synthesis of 3-deoxy-2-octulosonic acid derivatives and characterisation of their 3-deoxyoctitols☆

O. Holst, H. Brade, R. Schmidt, 1993 .

Structural characterization of gangliosides from resting and endotoxin-stimulated murine B lymphocytes.

J. Peter-Katalinic, H. Brade, H. Büntemeyer, 1993, Biochemistry.

The structure of the O-antigenic polysaccharide from lipopolysaccharide of Vibrio cholerae strain H11 (non-O1).

J. Thomas-Oates, O. Holst, E. Vinogradov, 1992, European journal of biochemistry.

The synthesis and characterisation of 2-O-(6-O-l-glycero-α,β-d-manno-heptopyranosyl-α-d-glycopyranosyl)- α,β-d-glucopyranose☆

O. Holst, H. Brade, A. Zamojski, 1992 .

Methylation analysis of non-glycosidic phosphoric diesters of carbohydrates

O. Holst, H. Brade, J. Thiem, 1989 .

Structural and immunochemical analysis of the lipopolysaccharide from Acinetobacter lwoffii F78 located outside Chlamydiaceae with a Chlamydia-specific lipopolysaccharide epitope.

H. Heine, O. Holst, G. Hübner, 2008, Chemistry.

Molecular requirement for interleukin 1 induction by lipopolysaccharide‐stimulated human monocytes: Involvement of the heptosyl‐2‐keto 3‐deoxyoctulosonate region

J. Cavaillon, H. Brade, M. Caroff, 1986, European journal of immunology.

Occurrence of 2-keto-deoxyoctonic acid 5-phosphate in lipopolysaccharides of Vibrio cholerae Ogawa and Inaba

H. Brade, 1985, Journal of bacteriology.

Studies on the reductive amination of 3-deoxy-D-manno-octulosonic acid (Kdo)

H. Brade, H. Grimmecke, 1998, Glycoconjugate Journal.

Structural investigation on the carbohydrate backbone of the lipopolysaccharide from Klebsiella pneumoniae rough mutant R20/O1-.

O. Holst, H. Brade, S. Müller-Loennies, 1995, Carbohydrate research.

The structure of the lipid A-core region of the lipopolysaccharides from Vibrio cholerae O1 smooth strain 569B (Inaba) and rough mutant strain 95R (Ogawa).

O. Holst, E. Vinogradov, H. Brade, 1995, European journal of biochemistry.

Chemical structure of the lipid A of Escherichia coli J-5.

O. Holst, B. Lindner, H. Brade, 1993, European journal of biochemistry.

Structural investigation on the lipopolysaccharide of Escherichia coli rough mutant F653 representing the R3 core type.

O. Holst, H. Brade, Y. Haishima, 1992, European journal of biochemistry.

Structural analysis of the heptose/hexose region of the lipopolysaccharide from Escherichia coli K-12 strain W3100.

O. Holst, U. Zähringer, H. Brade, 1991, Carbohydrate research.

Identification of D-galactose-(1 7)-3-deoxy-d-manno-2-octulo-pyranosonate as component of the inner core region of escherichia coli EH 100 lipopolysaccharide

O. Holst, H. Brade, H. Cordes, 1990 .

Isolation and identification of 3-deoxy-7-O-alpha-D-galactopyranosyl-D-manno-2-octulopyranosonate++ + from the inner core region of the lipopolysaccharide of Escherichia coli EH100.

O. Holst, H. Brade, H. Cordes, 1989, Carbohydrate research.

Isolation and chemical analysis of 7-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-L-glycero-D-manno-heptose as a constituent of the lipopolysaccharides of the UDP-galactose epimerase-less mutant J-5 of Escherichia coli and Vibrio cholerae.

E. Rietschel, U. Zähringer, H. Brade, 1988, Carbohydrate research.

Induction of tumor necrosis factor-alpha release by lipopolysaccharide and defined lipopolysaccharide partial structures.

H. Flad, A. Ulmer, H. Brade, 1989, Immunobiology.

Molecular cloning, sequence analysis, and functional characterization of the lipopolysaccharide biosynthetic gene kdtA encoding 3‐deoxy‐α‐d‐manno‐octulosonic acid transf erase of Chlamydia pneumoniae strain TW‐183

H. Brade, U. Mamat, W. Brabetz, 1995, Molecular microbiology.

Sphingolipid metabolism during epidermal barrier development in mice DOI 10.1194/jlr.M200208-JLR200

H. Brade, K. Sandhoff, T. Doering, 2002, Journal of Lipid Research.

Biochemistry and cell biology of bacterial endotoxins.

H. Flad, O. Holst, A. Ulmer, 1996, FEMS immunology and medical microbiology.

Biochemistry and cell biology of bacterial endotoxins MiniReview

H. Flad, O. Holst, A. Ulmer, 1996 .

Determination of the epitope specificity of monoclonal antibodies against the inner core region of bacterial lipopolysaccharides by use of 3-deoxy-D-manno-octulosonate-containing synthetic antigens.

H. Brade, S. Kusumoto, B. Appelmelk, 1989, Carbohydrate research.

Synthesis and immunochemical characterization of neoglycoproteins containing epitopes of the inner core region of Pseudomonas aeruginosa RNA group I lipopolysaccharide

H. Brade, L. Brade, P. Kosma, 2001, Journal of endotoxin research.

In vitro characterization of anti-glucosylceramide rabbit antisera.

E. Heinz, H. Brade, L. Brade, 2000, Glycobiology.

The structures of oligosaccharide bisphosphates isolated from the lipopolysaccharide of a recombinant Escherichia coli strain expressing the gene gseA [3-deoxy-D-manno-octulopyranosonic acid (Kdo) transferase] of Chlamydia psittaci 6BC.

O. Holst, H. Brade, L. Brade, 1995, European journal of biochemistry.

Occurrence of antibodies against chlamydial lipopolysaccharide in human sera as measured by ELISA using an artificial glycoconjugate antigen.

M. Ernst, O. Holst, H. Brade, 1994, FEMS immunology and medical microbiology.

Endotoxic activity and chemical structure of lipopolysaccharides from Chlamydia trachomatis serotypes E and L2 and Chlamydophila psittaci 6BC.

H. Heine, B. Lindner, H. Brade, 2003, European journal of biochemistry.

Binding of lipopolysaccharide (LPS) to an 80-kilodalton membrane protein of human cells is mediated by soluble CD14 and LPS-binding protein

H. Flad, A. Ulmer, E. Rietschel, 1995, Infection and immunity.

Soluble peptidoglycan-induced monokine production can be blocked by anti-CD14 monoclonal antibodies and by lipid A partial structures

H. Flad, A. Ulmer, E. Rietschel, 1994, Infection and immunity.

An artificial glycoconjugate containing the bisphosphorylated glucosamine disaccharide backbone of lipid A binds lipid A monoclonal antibodies

O. Holst, H. Brade, L. Brade, 1993, Infection and immunity.

Specificity of rabbit antisera against the rough lipopolysaccharide of Salmonella minnesota strain R7 (chemotype Rd1P-).

H. Brade, L. Brade, A. Swierzko, 1993, FEMS immunology and medical microbiology.

Chemical structure of the lipopolysaccharide of Haemophilus influenzae strain I-69 Rd-/b+. Description of a novel deep-rough chemotype.

B. Lindner, E. Rietschel, U. Zähringer, 1988, European journal of biochemistry.

Studies on the chemical structure of the core-lipid A region of the lipopolysaccharide of Acinetobacter calcoaceticus NCTC 10305. Detection of a new 2-octulosonic acid interlinking the core oligosaccharide and lipid A component.

U. Zähringer, H. Brade, E. Rietschel, 1987, European journal of biochemistry.

Use of synthetic antigens to determine the epitope specificities of monoclonal antibodies against the 3-deoxy-D-manno-octulosonate region of bacterial lipopolysaccharide

H. Brade, B. Appelmelk, L. Brade, 1987, Infection and immunity.

Chemical, biological, and immunochemical properties of the Chlamydia psittaci lipopolysaccharide

H. Brade, U. Schade, L. Brade, 1986, Infection and immunity.

Methylation analysis of the heptose/3-deoxy-D-manno-2-octulosonic acid region (inner core) of the lipopolysaccharide from Salmonella minnesota rough mutants.

H. Brade, E. Rietschel, A. Tacken, 1986, Carbohydrate research.

The effect of removal of D-fructose on the antigenicity of the lipopolysaccharide from a rough mutant of Vibrio cholerae Ogawa.

H. Brade, E. Rietschel, L. Brade, 1986, Carbohydrate research.

Characterization of two different antibody specificities recognizing distinct antigenic determinants in free lipid A of Escherichia coli

H. Brade, L. Brade, 1985, Infection and immunity.

Chemical characterization of Chlamydia trachomatis lipopolysaccharide

H. Brade, E. Rietschel, M. Nurminen, 1985, Infection and immunity.

Isolation, Purification, and Chemical Analysis of the Lipopolysaccharide Analysis of the Lipopolysaccharide and Lipid A of Acinetobacter calcoaceticus NCTC 10305

C. Galanos, H. Brade, 1982 .

Neutrophil Granulocytes and Delay Their Multiply in Chlamydia pneumoniae

Eresso Aga, W. Solbach, T. Laskay, 2004 .

Specificity of Rabbit Antisera against Lipopolysaccharide of Acinetobacter

L. Dijkshoorn, H. Brade, L. Brade, 1998, Journal of Clinical Microbiology.

Recognition of heptoses and the inner core of bacterial lipopolysaccharides by surfactant protein d.

B. Seaton, H. Brade, Tanya R. Cafarella, 2008, Biochemistry.

A cDNA encoding 3-deoxy-d-manno-oct-2-ulosonate-8-phosphate synthase of Pisum sativum L. (pea) functionally complements a kdsA mutant of the Gram-negative bacterium Salmonella enterica

H. Brade, W. Brabetz, F. P. Wolter, 2000, Planta.

Salmonella lipopolysaccharides . antibody binding to Escherichia coli and A broadly cross-protective monoclonal

G. Ramsay, R. Lan, G. Barclay, 2003 .

The Combining Sites of Anti-lipid A Antibodies Reveal a Widely Utilized Motif Specific for Negatively Charged Groups*

H. Brade, L. Brade, S. V. Evans, 2016, The Journal of Biological Chemistry.

Structural Basis for Antibody Recognition of Lipid A

H. Brade, L. Brade, S. V. Evans, 2015, The Journal of Biological Chemistry.

Newer aspects of the chemical structure and biological activity of bacterial endotoxins.

B. Lindner, E. Rietschel, H. Brade, 1985, Progress in clinical and biological research.

Endotoxic properties of chemically synthesized lipid A part structures. Comparison of synthetic lipid A precursor and synthetic analogues with biosynthetic lipid A precursor and free lipid A.

K. Tanamoto, E. Rietschel, C. Galanos, 1984, European journal of biochemistry.

Cellular Recognition of Trimyristoylated Peptide or Enterobacterial Lipopolysaccharide via Both TLR2 and TLR4*

T. Hartung, W. Bessler, K. Pfeffer, 2007, Journal of Biological Chemistry.

Lipid A, the endotoxic center of bacterial lipopolysaccharides: relation of chemical structure to biological activity.

E. Rietschel, C. Galanos, U. Zähringer, 1987, Progress in clinical and biological research.

Concepts of the chemical structure of lipid A.

U. Zähringer, H. Brade, E. Rietschel, 1984, Reviews of infectious diseases.

Synthesis and purity assessment of tetra- and pentaacyl lipid A of Chlamydia containing (R)-3-hydroxyicosanoic acid

H. Brade, P. Kosma, A. Zamyatina, 2004 .

Review: Chlamydial lipopolysaccharide

H. Brade, L. Brade, U. Mamat, 1997 .

Chemical and serological investigations on the genus-specific lipopolysaccharide epitope of Chlamydia.

H. Brade, L. Brade, F. Nano, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Gonococcal rfaF mutants express Rd2 chemotype LPS and do not enter epithelial host cells

B. Robertson, H. Brade, J. Putten, 1995, Molecular microbiology.

Anti-Chlamydophila immunoglobulin prevalence in sarcoidosis and usual interstitial pneumoniae

M. Schlaak, H. Brade, L. Brade, 2002, European Respiratory Journal.

The chemical structure of the lipopolysaccharide of A Rc-type mutant of Proteus mirabilis lacking 4-amino-4-deoxy-L arabinose and its susceptibility towards polymyxin B.

H. Brade, H. Mayer, W. Kaca, 1990, Advances in experimental medicine and biology.

Structural studies on the core and lipid A region of a 4-amino-L-arabinose-lacking Rc-type mutant of Proteus mirabilis.

H. Brade, H. Mayer, J. Radziejewska-Lebrecht, 1988, European journal of biochemistry.

Isolation and structural characterization of an 8-O-(4-amino-4-deoxy-beta-L-arabinopyranosyl)-3-deoxy-D-manno- octulosonic acid disaccharide in the lipopolysaccharide of a Proteus mirabilis deep rough mutant.

E. Rietschel, U. Zähringer, H. Brade, 1987, European journal of biochemistry.

Neutralizing and cross-reactive antibodies against enterobacterial lipopolysaccharide.

H. Brade, L. Brade, S. Müller-Loennies, 2007, International journal of medical microbiology : IJMM.

A method to detect 2-keto-3-deoxyoctanat and related compounds on pherograms and chromatograms.

C. Galanos, H. Brade, 1983, Analytical biochemistry.

Chemical and antigenic structure of the O-polysaccharide of the lipopolysaccharides from two Acinetobacter haemolyticus strains differing only in the anomeric configuration of one glycosyl residue in their O-antigens.

O. Holst, E. Vinogradov, H. Brade, 1999, European journal of biochemistry.

Detection of lipid A by monoclonal antibodies in S-form lipopolysaccharide after acidic treatment of immobilized LPS on Western blot

H. Brade, L. Brade, R. Pantophlet, 1997 .

Separation of wild-type lipopolysaccharides by centrifugal partition chromatography: isolation of smooth form species

E. Rietschel, H. Brade, S. Kusumoto, 1996 .

Differential determination of the 3-Deoxy-D-mannooctulosonic acid residues in lipopolysaccharides of Salmonella minnesota rough mutants.

C. Galanos, H. Brade, O. Lüderitz, 1983, European journal of biochemistry.

The Gram-negative bacterium Chlamydia trachomatis L2 stimulates tumor necrosis factor secretion by innate immune cells independently of its endotoxin.

H. Wagner, T. Miethke, H. Brade, 2003, Microbes and infection.

Endotoxin-tolerant mice produce an inhibitor of tumor necrosis factor synthesis

F. Schade, H. Brade, J. Schlegel, 1996 .

Mouse anti-ceramide antiserum: a specific tool for the detection of endogenous ceramide.

R. Wepf, K. Wittern, H. Brade, 2001, Glycobiology.

Characterization of a Neutralizing Monoclonal Antibody Directed at the Lipopolysaccharide of Chlamydia pneumoniae

H. Brade, L. Brade, E. Peterson, 1998, Infection and Immunity.

Antibodies to Chlamydia trachomatis heat shock proteins in women with tubal factor infertility are associated with prior infection by C. trachomatis but not by C. pneumoniae.

H. Brade, S. Birkelund, G. Christiansen, 1999, Human reproduction.

Characterization of the epitope specificity of murine monoclonal antibodies directed against lipid A

H. Brade, S. Kusumoto, E. Rietschel, 1992, Infection and immunity.

Epitope specificities of murine monoclonal and rabbit polyclonal antibodies against enterobacterial lipopolysaccharides of the Re chemotype

H. Brade, B. Appelmelk, L. Brade, 1989, Infection and immunity.

Monoclonal antibody S60-4-14 reveals diagnostic potential in the identification of Pseudomonas aeruginosa in lung tissues of cystic fibrosis patients.

T. Goldmann, T. Welte, P. S. Sánchez Carballo, 2010, European journal of cell biology.

Molecular Aspects of the Chemistry and Biology of Endotoxin

T. Kirikae, P. Zabel, M. Schlaak, 1991 .

Characterization of high affinity monoclonal antibodies specific for chlamydial lipopolysaccharide.

C R MacKenzie, S V Evans, C. MacKenzie, 2000, Glycobiology.

Antibodies raised against chlamydial lipopolysaccharide antigens reveal convergence in germline gene usage and differential epitope recognition.

C. MacKenzie, C. Brooks, H. Brade, 2010, Biochemistry.

Synthesis and antigenic properties of C-7-modified Kdo mono- and disaccharide ligands and Kdo disaccharide interresidue lactones.

H. Brade, A. Hofinger, P. Kosma, 2009, Carbohydrate research.

Conformational analysis of a Chlamydia-specific disaccharide α-Kdo-(2→8)-α-Kdo-(2→O)-allyl in aqueous solution and bound to a monoclonal antibody: Observation of intermolecular transfer NOEs

H. Brade, L. Brade, T. Haselhorst, 1998 .

Conformational analysis of a Chlamydia-specific disaccharide alpha-Kdo-(2-->8)-alpha-Kdo-(2-->O)-allyl in aqueous solution and bound to a monoclonal antibody: observation of intermolecular transfer NOEs.

H. Brade, L. Brade, T. Haselhorst, 1998, Journal of biomolecular NMR.

Structural requirements of synthetic oligosaccharides to bind monoclonal antibodies against Chlamydia lipopolysaccharide.

H. Brade, L. Brade, K. Bock, 1997, Glycobiology.

Crystal and molecular structure of allyl O-(sodium 3-deoxy-α-d-manno- 2-octulopyranosylonate)-(2 → 8)-O-(sodium 3-deoxy-α-d-manno- 2-octulopyranosidonate)-monohydrate

H. Brade, V. Mikol, P. Kosma, 1994 .

A synthetic glycoconjugate representing the genus-specific epitope of chlamydial lipopolysaccharide exhibits the same specificity as its natural counterpart

H. Brade, L. Brade, P. Kosma, 1992, Infection and immunity.

Lipopolysaccharide smooth-rough phase variation in bacteria of the genus Chlamydia

H. Brade, L. Brade, U. Mamat, 1994, Infection and immunity.

Invited review: Lipopolysaccharide biosynthesis: which steps do bacteria need to survive?

S. Gronow, H. Brade, 2001 .

Kdo-(2 → 8)-Kdo-(2 → 4)-Kdo but not Kdo-(2 → 4)-Kdo-(2 → 4)-Kdo is an acceptor for transfer of L-glycero-α-D-manno-heptose by Escherichia coli heptosyltransferase I (WaaC)

S. Gronow, B. Lindner, H. Brade, 2009, Innate immunity.

The structure of the carbohydrate backbone of the lipopolysaccharide from Acinetobacter baumannii strain ATCC 19606.

O. Holst, E. Vinogradov, H. Brade, 2002, European journal of biochemistry.

Comparative analyses of secondary gene products of 3-deoxy-D-manno-oct-2-ulosonic acid transferases from Chlamydiaceae in Escherichia coli K-12.

B. Lindner, H. Brade, W. Brabetz, 2000, European journal of biochemistry.

Structural analysis of the lipopolysaccharide from Chlamydophila psittaci strain 6BC.

O. Holst, B. Lindner, H. Brade, 2000, European journal of biochemistry.

3-Deoxy-d-manno-oct-2-ulosonic Acid (Kdo) Transferase of Legionella pneumophila Transfers Two Kdo Residues to a Structurally Different Lipid A Precursor ofEscherichia coli

H. Brade, W. Brabetz, Christiane E. Schirmer, 2000, Journal of bacteriology.

Characterization of a Novel Branched Tetrasaccharide of 3-Deoxy-d-manno-oct-2-ulopyranosonic Acid

J. Thomas-Oates, O. Holst, E. Vinogradov, 1998, The Journal of Biological Chemistry.

Cloning and characterization of 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) transferase genes (kdtA) from Acinetobacter baumannii and Acinetobacter haemolyticus.

H. Brade, W. Brabetz, C. Bode, 1998, European journal of biochemistry.

The structure of the carbohydrate backbone of the lipopolysaccharide from Acinetobacter strain ATCC 17905.

O. Holst, E. Vinogradov, H. Brade, 1997, European journal of biochemistry.

A nuclear magnetic resonance spectroscopic investigation of Kdo-containing oligosaccharides related to the genus-specific epitope of Chlamydia lipopolysaccharides.

O. Holst, H. Brade, K. Bock, 1992, Carbohydrate research.

Intact rough‐ and smooth‐form lipopolysaccharides from Escherichia coli separated by preparative gel electrophoresis exhibit differential biologic activity in human macrophages

B. Lindner, H. Brade, A. Schromm, 2013, The FEBS journal.

Lipopolysaccharide and peptidoglycan: CD14-dependent bacterial inducers of inflammation.

H. Flad, A. Ulmer, E. Rietschel, 1998, Microbial drug resistance.

Inhibition of LPS binding on human monocytes by phosphonooxyethyl analogs of lipid A

H. Flad, H. Heine, A. Ulmer, 1994 .

Modulation of endotoxin-induced monokine release in human monocytes by lipid A partial structures that inhibit binding of 125I-lipopolysaccharide

T. Kirikae, H. Heine, A. Ulmer, 1992, Infection and immunity.

Structural Analysis of Oligosaccharides from Lipopolysaccharide (LPS) of Escherichia coli K12 Strain W3100 Reveals a Link between Inner and Outer Core LPS Biosynthesis*

B. Lindner, H. Brade, S. Müller-Loennies, 2003, Journal of Biological Chemistry.

Diagnosis of ornithosis by cell culture and polymerase chain reaction in a patient with chronic pneumonia.

S. Wieshammer, P. Zucs, H. Brade, 1995, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Induction of cytokines in mononuclear and vascular cells by endotoxin and other bacterial products.

H. Flad, E. Rietschel, H. Brade, 1994, Methods in enzymology.

Inhibition of endotoxin-induced interleukin-6 production by synthetic lipid A partial structures in human peripheral blood mononuclear cells

H. Flad, A. Ulmer, E. Rietschel, 1991, Infection and immunity.

Suppressive effect of lipid A partial structures on lipopolysaccharide or lipid A-induced release of interleukin 1 by human monocytes.

H. Flad, A. Ulmer, E. Rietschel, 1990, FEMS microbiology immunology.

Structure, serological specificity, and synthesis of artificial glycoconjugates representing the genus-specific lipopolysaccharide epitope of Chlamydia spp

O. Holst, H. Brade, L. Brade, 1991, Journal of bacteriology.

Isolation of a 3-deoxy-D-mannooctulosonic acid disaccharide from Salmonella minnesota rough-form lipopolysaccharides.

C. Galanos, H. Brade, O. Lüderitz, 1983, European journal of biochemistry.

IL-1 induction-capacity of defined lipopolysaccharide partial structures.

H. Flad, C. Dinarello, E. Rietschel, 1989, Journal of immunology.

Monoclonal antibodies against the heptose region of enterobacterial lipopolysaccharides

H. Brade, L. Brade, W. Brabetz, 1994 .

Lipopolysaccharide biosynthesis: which steps do bacteria need to survive?

S. Gronow, H. Brade, 2001, Journal of endotoxin research.

Surfactant Protein D Binds Selectively to Klebsiella pneumoniae Lipopolysaccharides Containing Mannose-Rich O-Antigens1

H. Brade, E. Crouch, R. Podschun, 2002, The Journal of Immunology.

Containing Mannose-Rich O-Antigens Lipopolysaccharides Klebsiella pneumoniae Surfactant Protein D Binds Selectively to

H. Brade, E. Crouch, R. Podschun, 2002 .

Synthesis of C-8 Deuterated Glycosides of 3-Deoxy-D-manno-oct-2-ulosonic Acid (Kdo) Related to Chlamydial Lipopolysaccharides

H. Brade, J. Duus, A. Hofinger, 2002 .

A monoclonal antibody recognizing the 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) trisaccharide αKdo(2→4)αKdo(2→4)αKdo of Chlamydophila spacepsittaci 6BC lipopolysaccharide

H. Brade, L. Brade, A. Różalski, 2000 .

Characterization of serum antibody response to chlamydiae in patients with sexually acquired reactive arthritis.

H. Brade, L. Brade, S. Witkin, 2006, FEMS immunology and medical microbiology.

Staining of surface antigens of Chlamydia trachomatis L2 in tissue culture

H. Brade, L. Brade, E. Fasske, 1992, Infection and immunity.

Characterization of murine monoclonal and murine, rabbit, and human polyclonal antibodies against chlamydial lipopolysaccharide

O. Holst, H. Brade, L. Brade, 1990, Infection and immunity.

Antigenic and immunogenic properties of recombinants from Salmonella typhimurium and Salmonella minnesota rough mutants expressing in their lipopolysaccharide a genus-specific chlamydial epitope

H. Brade, L. Brade, S. Schramek, 1987, Infection and immunity.

Antigenic properties of Chlamydia trachomatis lipopolysaccharide

H. Brade, L. Brade, M. Nurminen, 1985, Infection and immunity.

Bacterial Endotoxins: Relationships Between Chemical Structure and Biological Activity

H. Flad, E. Rietschel, U. Zähringer, 1989 .

Common lipopolysaccharide specificity: new type of antigen residing in the inner core region of S- and R-form lipopolysaccharides from different families of gram-negative bacteria

C. Galanos, H. Brade, Helmut BRADEt, 1983, Infection and immunity.

Structure, endotoxicity, immunogenicity and antigenicity of bacterial lipopolysaccharides (endotoxins, O-antigens).

O. Holst, U. Zähringer, H. Brade, 1988, Progress in clinical and biological research.

Immunogenic properties of lipid A.

C. Galanos, M. Freudenberg, H. Brade, 1984, Reviews of infectious diseases.

Glycosyltransferases involved in the biosynthesis of the inner core region of different lipopolysaccharides.

S. Gronow, H. Brade, G. Xia, 2010, European journal of cell biology.

Molecular and Structural Basis of Inner Core Lipopolysaccharide Alterations in Escherichia coli

B. Lindner, H. Brade, S. Raina, 2013, The Journal of Biological Chemistry.

Molecular Basis of Lipopolysaccharide Heterogeneity in Escherichia coli

B. Lindner, H. Brade, S. Raina, 2011, The Journal of Biological Chemistry.

Lipopolysaccharides: structural principles and biologic activities.

K. Tanamoto, E. Rietschel, C. Galanos, 1984, Reviews of infectious diseases.

Investigation on the agonistic and antagonistic biological activities of synthetic Chlamydia lipid A and its use in in vitro enzymatic assays

S. Gronow, H. Heine, H. Brade, 2007, Journal of endotoxin research.

Specificity of monoclonal antibodies against Escherichia coli K-12 lipopolysaccharide

O. Holst, H. Brade, L. Brade, 1996 .

Synthesis of inner core antigens related to Chlamydia, Pseudomonas and Acinetobacter LPS

N. Wimmer, H. Brade, P. Kosma, 1999 .

Synthesis of deoxy analogues of (2→8)-linked 3-deoxy-α-D-manno-oct-2-ulopyranosylonic acid (Kdo) disaccharides for binding studies with Chlamydia specific monoclonal antibodies

H. Brade, P. Kosma, R. Müller, 1997 .

Prevention of lethal endotoxemia in actinomycin D-sensitized mice by incubation of Salmonella minnesota R595 lipopolysaccharide with monoclonal antibodies to R595.

H. Brade, B. Appelmelk, J. Maaskant, 1988, Microbial pathogenesis.

Endotoxin in Health and Disease

H. Brade, Helmut Brade, 2020 .

Efficient Synthesis of 4-Amino-4-deoxy-L-arabinose and Spacer-equipped 4-Amino-4-deoxy-L-arabinopyranosides by Transglycosylation Reactions.

H. Brade, A. Hofinger, Bernhard Müller, 2010, Synthesis.

Investigations into the polymorphism of lipid A from lipopolysaccharides of Escherichia coli and Salmonella minnesota by Fourier-transform infrared spectroscopy.

D. Naumann, H. Brade, K. Brandenburg, 1987, European journal of biochemistry.

Escherichia coli K-12 Suppressor-free Mutants Lacking Early Glycosyltransferases and Late Acyltransferases

B. Lindner, H. Brade, S. Raina, 2009, The Journal of Biological Chemistry.

Bacterial endotoxin: Chemical constitution, biological recognition, host response, and immunological detoxification.

R R Schumann, U Seydel, H. Flad, 1996, Current topics in microbiology and immunology.

Structural and serological characterisation of the O-antigenic polysaccharide of the lipopolysaccharide from Acinetobacter junii strain 65.

O. Holst, H. Brade, L. Brade, 1997, European journal of biochemistry.

Identification of Acinetobacter Isolates from Species Belonging to the Acinetobacter calcoaceticus-Acinetobacter baumannii Complex with Monoclonal Antibodies Specific for O Antigens of Their Lipopolysaccharides

L. Dijkshoorn, H. Brade, L. Brade, 2002, Clinical and Vaccine Immunology.

Identification of Acinetobacter baumannii Strains with Monoclonal Antibodies against the O Antigens of Their Lipopolysaccharides

H. Brade, L. Brade, R. Pantophlet, 1999, Clinical Diagnostic Laboratory Immunology.

A Novel 40-kDa Protein Containing Six Repeats of an Epidermal Growth Factor-Like Domain Functions as a Pattern Recognition Protein for Lipopolysaccharide1

H. Brade, L. Brade, I. Söderhäll, 2006, The Journal of Immunology.

Protein for Lipopolysaccharide Domain Functions as a Pattern Recognition Factor-LikeRepeats of an Epidermal Growth A Novel 40-kDa Protein Containing Six Söderhäll

H. Brade, L. Brade, I. Söderhäll, 2006 .

Use of a Murine O-Antigen-Specific Monoclonal Antibody To Identify Acinetobacter Strains of Unnamed Genomic Species 13 Sensu Tjernberg and Ursing

H. Brade, L. Brade, R. Pantophlet, 1999, Journal of Clinical Microbiology.

Synthesis of a tetrasaccharide of the genus-specific lipopolysaccharide epitope of Chlamydia.

H. Brade, P. Kosma, G. Schulz, 1990, Carbohydrate research.

Synthesis of trisaccharides containing 3-deoxy-D-manno-2-octulosonic acid residues related to the KDO-region of enterobacterial lipopolysaccharides.

H. Brade, F. Unger, P. Kosma, 1989, Carbohydrate research.

Synthesis of a trisaccharide of 3-deoxy-D-manno-2-octulopyranosylonic acid (KDO) residues related to the genus-specific lipopolysaccharide epitope of Chlamydia.

H. Brade, P. Kosma, G. Schulz, 1988, Carbohydrate research.

Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS

F. D. Di Padova, C. Brooks, H. Brade, 2012, Proceedings of the National Academy of Sciences.

A broadly cross-protective monoclonal antibody binding to Escherichia coli and Salmonella lipopolysaccharides

G. Ramsay, F. D. Di Padova, F. Padova, 1993, Infection and immunity.

Synthesis and immunoreactivity of poly(acrylamide) copolymers containing C-3- and C-7-modified, carboxyl-reduced, 4-O- and 5-O-phosphorylated K

K. Fukase, H. Brade, S. Kusumoto, 1993 .

Groove-type Recognition of Chlamydiaceae-specific Lipopolysaccharide Antigen by a Family of Antibodies Possessing an Unusual Variable Heavy Chain N-Linked Glycan*

P. Rudd, H. Brade, L. Brade, 2014, The Journal of Biological Chemistry.

Synthesis of neoglycoproteins containingL-glycero-α-D-manno-heptopyranosyl-(1→4)- and -(1→5)-linked3-deoxy-α-D-manno-oct-2-ulopyranosylonic acid (Kdo) phosphate determinants

N. Wimmer, H. Brade, A. Hofinger, 1997 .

Synthesis of neoglycoproteins containing 5-O-phosphorylated Kdomonosaccharide, 4-O- and 5-O-phosphorylated α-Kd↬(2 6)-2-acetamido-2-deoxy- -D-glucopyranosyl disaccharide residues

K. Fukase, H. Brade, S. Kusumoto, 1996 .

Synthesis of carboxyl-reduced analogues related to the Chlamydia-specific Kdo trisaccharide epitope.

F. D’Souza, H. Brade, P. Kosma, 1994, Carbohydrate research.

Synthesis of pentasaccharide core structures corresponding to the genus-specific lipopolysaccharide epitope of Chlamydia.

H. Brade, G. Allmaier, M. Strobl, 1994, Carbohydrate research.

Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.

C. MacKenzie, F. van Petegem, C. Brooks, 2018, Biochemistry.

Synthesis of a neoglycoconjugate containing a Chlamydophila psittaci-specific branched Kdo trisaccharide epitope.

H. Brade, A. Hofinger, S. Müller-Loennies, 2010, Carbohydrate research.

Monoclonal antibodies against 3-deoxy-α-D-manno-oct-2-ulosonic acid (Kdo) and D-glycero-α-D-talo-oct-2-ulosonic acid (Ko)

S. Gronow, N. Wimmer, H. Brade, 2002 .

Monoclonal antibodies against 3-deoxy-α-D-manno-oct-2-ulosonic acid (Kdo) and D-glycero-α-D-talo-oct-2-ulosonic acid (Ko):

S. Gronow, N. Wimmer, H. Brade, 2002 .

Synthesis of neoglycoproteins containing D-glycero-D-talo-oct-2-ulopyranosylonic acid (Ko) ligands corresponding to core units from Burkholderia and Acinetobacter lipopolysaccharide.

N. Wimmer, H. Brade, P. Kosma, 2000, Carbohydrate research.

Characterization of monoclonal antibodies recognizing three distinct, phosphorylated carbohydrate epitopes in the lipopolysaccharide of the deep rough mutant I‐69 Rd−/b+ of Haemophilus influenzae

H. Brade, S. Kusumoto, L. Brade, 1997, Molecular microbiology.

Synthesis of Kdo-trisaccharide derivatives of chlamydial and enterobacterial LPS containing carboxyl-reduced or β-configurated Kdo-residues

F. D’Souza, H. Brade, P. Kosma, 1995 .

Synthesis and NMR spectroscopic investigation of oligosaccharides containing Kdo and L-glycero-D-manno-heptopyranosyl residues.

H. Brade, A. Hofinger, K. Bock, 1993, Carbohydrate research.

Use of Antibodies to the Lipopolysaccharide Core Region in the Treatment of Gram-negative Sepsis and Shock

L. Thijs, H. Brade, J. Cohen, 1990, 1990.

α‐2→4‐Interlinked 3‐deoxy‐d‐manno‐octulosonic acid disaccharide

H. Brade, E. Rietschel, 1984 .

Spectroscopic analysis of a 3-deoxy-d-manno-2-octulosonic acid (KDO)-disaccharide from the lipopolysaccharide of a Salmonella godesberg Re mutant

E. Rietschel, U. Zähringer, H. Brade, 1984 .

A novel strategy for the synthesis of neoglycoconjugates from deacylated deep rough lipopolysaccharides

B. Lindner, H. Brade, L. Brade, 2002, Journal of endotoxin research.

GLC-MS of reduced, acetylated, and methylated (2----4)- and (2----8)-linked disaccharides of 3-deoxy-D-manno-octulopyranosonic acid (Kdo).

O. Holst, H. Brade, P. Kosma, 1992, Carbohydrate research.

Bacterial Endotoxins: Relationships between Chemical Structure and Biological Activity of the Inner Core-Lipid a Domain

O. Holst, E. Rietschel, U. Zähringer, 1991 .

Isolation and identification of a rhamnosyl-rhamnosyl-3-deoxy-D-manno-octulosonic acid trisaccharide from the lipopolysaccharide of Acinetobacter calcoaceticus (10303 NTCC London).

H. Brade, R. Christian, A. Tacken, 1987, Carbohydrate research.

G.L.C.-M.S. of partially methylated and acetylated derivatives of 3-deoxyoctitols

H. Brade, F. Unger, D. Charon, 1986 .

The role of CDR H3 in antibody recognition of a synthetic analog of a lipopolysaccharide antigen.

C. MacKenzie, C. Brooks, H. Brade, 2010, Glycobiology.

Isolation and structural analysis of phosphorylated oligosaccharides obtained from Escherichia coli J-5 lipopolysaccharide.

O. Holst, B. Lindner, H. Brade, 1999, European journal of biochemistry.

Structural and serological characterisation of the O-antigenic polysaccharide of the lipopolysaccharide from Acinetobacter strain 90 belonging to DNA group 10.

O. Holst, H. Brade, S. Haseley, 1997, European journal of biochemistry.

Structural and serological characterisation of the O-antigenic polysaccharide of the lipopolysaccharide from Acinetobacter haemolyticus strain ATCC 17906.

O. Holst, H. Brade, S. Haseley, 1997, European journal of biochemistry.

Structural and serological characterisation of two O-specific polysaccharides of Acinetobacter.

L. Dijkshoorn, O. Holst, E. Vinogradov, 1996, European journal of biochemistry.

Structural investigation of the lipopolysaccharide from Acinetobacter haemolyticus strain NCTC 10305 (ATCC 17906, DNA group 4).

J. Thomas-Oates, O. Holst, E. Vinogradov, 1997, European journal of biochemistry.

A 28,000-dalton protein of normal mouse serum binds specifically to the inner core region of bacterial lipopolysaccharide

H. Brade, L. Brade, 1985, Infection and immunity.

A 28 kDa protein of normal mouse serum binds lipopolysaccharides of gram-negative and lipoteichoic acids of gram-positive bacteria.

H. Brade, W. Fischer, L. Brade, 1990, Microbial pathogenesis.

Identification of 2-keto-3-deoxy-1,7-dicarboxyheptonic acid as a constituent of the lipopolysaccharide of Acinetobacter calcoaceticus NCTC 10305.

H. Brade, E. Rietschel, 1985, European journal of biochemistry.

Isolation, purification, and chemical analysis of the lipopolysaccharide and lipid A of Acinetobacter calcoaceticus NCTC 10305.

C. Galanos, H. Brade, 1982, European journal of biochemistry.

G.l.c.-m.s. of methylated derivatives of 3-deoxy-2-ketoaldonic acid phosphates.

H. Brade, S. Sarfati, H. Moll, 1987, Carbohydrate research.

Biological activity of synthetic phosphonooxyethyl analogs of lipid A and lipid A partial structures

H. Flad, H. Heine, A. Ulmer, 1992, Infection and immunity.

Induction of human interleukin 1 by bacterial and synthetic lipid A

H. Flad, H. Brade, S. Kusumoto, 1986, European journal of immunology.

A lethal role for lipid A in Salmonella infections

I. Charles, G. Dougan, D. Maskell, 1998, Molecular microbiology.

Production, characterization and biological effects of monoclonal antibodies to different parts of the gram-negative lipopolysaccharide core region.

H. Brade, B. Appelmelk, J. Maaskant, 1988, Progress in clinical and biological research.

Germline antibody recognition of distinct carbohydrate epitopes

C. MacKenzie, H. Brade, L. Brade, 2003, Nature Structural Biology.

The immunogenicity and antigenicity of lipid A are influenced by its physicochemical state and environment

H. Brade, S. Kusumoto, E. Rietschel, 1987, Infection and immunity.

Further characterization of monoclonal antibodies to lipopolysaccharide of Salmonella Minnesota strain R595.

H. Brade, J. Cohen, A. Silva, 1990, Advances in experimental medicine and biology.

Structural investigations on the inner core region of lipopolysaccharides from Salmonella minnesota rough mutants.

H. Brade, E. Rietschel, H. Moll, 1985, Biomedical mass spectrometry.

Immunogenicity and antigenicity of synthetic Escherichia coli lipid A

H. Brade, S. Kusumoto, E. Rietschel, 1986, Infection and immunity.

The antibody reactivity of monoclonal lipid A antibodies is influenced by the acylation pattern of lipid A and the assay system employed.

H. Brade, S. Kusumoto, E. Rietschel, 1993, Immunobiology.

Specificity of rabbit antisera against the rough lipopolysaccharide of Salmonella minnesota R4 (chemotype Rd2P-)

H. Brade, L. Brade, H. Paulsen, 1993, Infection and immunity.

A complement-dependent enzyme immunoassay (C-EIA) with increased sensitivity for IgM-rich rabbit sera.

H. Brade, L. Brade, H. Kuhn, 1992, Journal of immunological methods.

Immunogenicity and antigenicity of natural and synthetic Escherichia coli lipid A.

H. Brade, S. Kusumoto, E. Rietschel, 1987, Progress in clinical and biological research.

Anti-endotoxin antibodies

F. Padova, E. Rietschel, H. Brade, 2005 .

PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide

Arthur S Slutsky, S. Ehlers, E. Gulbins, 2004, Nature Medicine.

A monoclonal antibody against a carbohydrate epitope in lipopolysaccharide differentiates Chlamydophila psittaci from Chlamydophila pecorum, Chlamydophila pneumoniae, and Chlamydia trachomatis.

Paul Kosma, Roger MacKenzie, S. Gronow, 2006, Glycobiology.

Critical Role for Interleukin-1β (IL-1β) during Chlamydia muridarum Genital Infection and Bacterial Replication-Independent Secretion of IL-1β in Mouse Macrophages

C. Andrews, T. Darville, R. Rank, 2009, Infection and Immunity.

A new lipopolysaccharide antigen identified in Acinetobacter calcoaceticus: occurrence of widespread natural antibody.

C. Galanos, H. Brade, 1983, Journal of medical microbiology.

Immunization with an anti-idiotypic antibody against the broadly lipopolysaccharide-reactive antibody WN1 222-5 induces Escherichia coli R3-core-type specific antibodies in rabbits

F. D. Di Padova, H. Heine, H. Brade, 2012, Innate immunity.

SHORT ARTICLES BIOLOGICAL ACTIVITIES OF THE LIPOPOLYSACCHARIDE AND LIPID A FROM ACINETOBACTER CALCOACETZCUS

C. Galanos, H. Brade, 1983 .

Exploring the cross-reactivity of S25-2: complex with a 5,6-dehydro-Kdo disaccharide.

C. Brooks, H. Brade, L. Brade, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

The genus‐specific lipopolysaccharide epitope of Chlamydia is assembled in C. psittaci and C. trachomatis by glycosyltransferases of low homology

H. Brade, G. Schmidt, U. Mamat, 1993, Molecular microbiology.

Identification of a Cross-reactive Epitope Widely Present in Lipopolysaccharide from Enterobacteria and Recognized by the Cross-protective Monoclonal Antibody WN1 222-5*

C. MacKenzie, F. D. Di Padova, H. Brade, 2003, Journal of Biological Chemistry.

Hemoglobin enhances the biological activity of synthetic and natural bacterial (endotoxic) virulence factors: a general principle.

A. Ulmer, E. Rietschel, H. Brade, 2008, Medicinal chemistry (Shariqah (United Arab Emirates)).

O-Antigen Diversity among Acinetobacter baumanniiStrains from the Czech Republic and Northwestern Europe, as Determined by Lipopolysaccharide-Specific Monoclonal Antibodies

L. Dijkshoorn, H. Brade, L. Brade, 2001, Journal of Clinical Microbiology.

Nucleotide sequence variations within the lipopolysaccharide biosynthesis gene gseA (Kdo transferase) among the Chlamydia trachomatis serovars.

H. Brade, U. Mamat, K. Persson, 1994, Microbial Pathogenesis.

[Persistence of latex agglutination inhibition antibodies in rabbits following application of poliomyelitis-, Coxsackie-, Echo- and encephalomyocarditis viruses. Brief report].

H. Brade, M. Klein, W. Schmidt, 1975, Archives of virology.

[The latex agglutination-inhibition test: a method for rapid antibody determination after enterovirus infection (author's transl)].

H. Brade, M. Klein, W. Schmidt, 1974, Deutsche Medizinische Wochenschrift.

The lipopolysaccharide of the mastitis isolate Escherichia coli strain 1303 comprises a novel O-antigen and the rare K-12 core type.

E. Brzuszkiewicz, U. Dobrindt, O. Holst, 2011, Microbiology.

Structural studies of the O-antigenic polysaccharide of the lipopolysaccharide from Acinetobacter (DNA group 11) strain 94 containing 3-amino-3,6-dideoxy-D-galactose substituted by the previously unknown amide-linked L-2-acetoxypropionic acid or L-2-hydroxypropionic acid.

O. Holst, H. Brade, S. Haseley, 1997, European journal of biochemistry.

Inhibition of endotoxin or lipid A-induced tumor necrosis factor production by synthetic lipid A partial structures in human peripheral blood mononuclear cells.

J. Gerdes, H. Flad, A. Ulmer, 1992, Lymphokine and cytokine research.

[Induction of early endotoxin tolerance with atoxic endotoxin--a new method for preventing sepsis syndrome].

H. Brade, H. Bruch, K. Staubach, 1998, Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress.

Mitogenic activities of synthetic Escherichia coli lipid A and a synthetic partial structure (tripalmitoyl pentapeptide) of E. coli lipoprotein

W. Bessler, H. Brade, L. Brade, 1988, Infection and immunity.

Interleukin 1 and tumor necrosis factor: studies on the induction by lipopolysaccharide partial structures.

H. Flad, A. Ulmer, E. Rietschel, 1989, Lymphokine research.

Molecular cloning, sequence analysis and functional characterization of the gene kdsA, encoding 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase of Chlamydia psittaci 6BC.

H. Brade, W. Brabetz, 1997, European journal of biochemistry.

Serological cross-reactions between Acinetobacter calcoaceticus and chlamydiae

H. Brade, H. Brunner, 1979, Journal of clinical microbiology.

Detection of chlamydial inclusion bodies with antisera to Acinetobacter calcoaceticus subspecies antitratus by indirect immunofluorescence

H. Brade, H. Brunner, 1980, Infection.

The structure of the carbohydrate backbone of the core-lipid-A region of the lipopolysaccharide from Vibrio cholerae strain H11 (non-O1).

O. Holst, E. Vinogradov, H. Brade, 1993, European journal of biochemistry.

NMR experiments reveal distinct antibody-bound conformations of a synthetic disaccharide representing a general structural element of bacterial lipopolysaccharide epitopes.

H. Brade, L. Brade, T. Haselhorst, 1999, Biochemistry.

Structural studies of the O-antigen isolated from the phenol-soluble lipopolysaccharide of Acinetobacter baumannii (DNA group 2) strain 9.

O. Holst, H. Brade, S. Haseley, 1998, European journal of biochemistry.

Antigen binding by conformational selection in near-germline antibodies

H. Brade, L. Brade, S. V. Evans, 2022, The Journal of biological chemistry.

Chemical structure and immunoreactivity of the lipopolysaccharide of the deep rough mutant I-69 Rd-/b+ of Haemophilus influenzae.

H. Brade, L. Brade, S. Müller-Loennies, 2002, European journal of biochemistry.

Isolation and characterisation of 3-deoxy-D-manno-2-octulopyranosonate 7-(2-aminoethyl phosphate) from the inner core region of Escherichia coli K-12 and Salmonella minnesota lipopolysaccharides.

O. Holst, H. Brade, E. Röhrscheidt-Andrzejewski, 1990, Carbohydrate research.

Structural studies of the core region of the lipopolysaccharide from Salmonella minnesota strain R7 (rough mutant chemotype Rd1).

O. Holst, H. Brade, 1991, Carbohydrate research.

Evaluation of a LPS-based glycoconjugate vaccine against bovine Escherichia coli mastitis: Formation of LPS Abs in cows after immunization with E. coli core oligosaccharides conjugated to hemocyanine

H. Brade, L. Brade, S. Hensen, 2013, Innate immunity.

Generation and Serological Characterization of Murine Monoclonal Antibodies against O Antigens from Acinetobacter Reference Strains

H. Brade, L. Brade, R. Pantophlet, 2001, Clinical Diagnostic Laboratory Immunology.

Structural analysis of deacylated lipopolysaccharide of Escherichia coli strains 2513 (R4 core-type) and F653 (R3 core-type).

B. Lindner, H. Brade, S. Müller-Loennies, 2002, European journal of biochemistry.

Analysis of cross-reactive and specific anti-carbohydrate antibodies against lipopolysaccharide from Chlamydophila psittaci.

C. MacKenzie, C. Brooks, H. Brade, 2010, Glycobiology.

OpsX from Haemophilus influenzae Represents a Novel Type of Heptosyltransferase I in Lipopolysaccharide Biosynthesis

S. Gronow, B. Lindner, H. Brade, 2005, Journal of bacteriology.

Chemical structure and biologic activity of bacterial and synthetic lipid A.

H. Flad, B. Lindner, E. Rietschel, 1987, Reviews of infectious diseases.

Critical Role for Interleukin-1β (IL-1β) during Chlamydia muridarum Genital Infection and Bacterial Replication-Independent Secretion of IL-1β in Mouse Macrophages

C. Andrews, T. Darville, R. Rank, 2009, Infection and Immunity.

Determination of 3-deoxy-D-manno-octulosonic acid (KDO), N-acetylneuraminic acid, and their derivatives by ion-exchange liquid chromatography.

U. Zähringer, H. Brade, E. Rietschel, 1985, Carbohydrate research.

Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS

F. D. Di Padova, C. Brooks, H. Brade, 2012, Proceedings of the National Academy of Sciences.

Structural insights into parallel strategies for germline antibody recognition of lipopolysaccharide from Chlamydia.

C. Brooks, H. Brade, L. Brade, 2011, Glycobiology.

Molecular and Structural Basis of Inner Core Lipopolysaccharide Alterations in Escherichia coli

B. Lindner, H. Brade, S. Raina, 2013, The Journal of Biological Chemistry.

Escherichia coli K-12 Suppressor-free Mutants Lacking Early Glycosyltransferases and Late Acyltransferases

B. Lindner, H. Brade, S. Raina, 2009, The Journal of Biological Chemistry.

Intact rough‐ and smooth‐form lipopolysaccharides from Escherichia coli separated by preparative gel electrophoresis exhibit differential biologic activity in human macrophages

B. Lindner, H. Brade, A. Schromm, 2013, The FEBS journal.

Kdo-(2 → 8)-Kdo-(2 → 4)-Kdo but not Kdo-(2 → 4)-Kdo-(2 → 4)-Kdo is an acceptor for transfer of L-glycero-α-D-manno-heptose by Escherichia coli heptosyltransferase I (WaaC)

S. Gronow, B. Lindner, H. Brade, 2009, Innate immunity.

3-Deoxy-d-manno-oct-2-ulosonic Acid (Kdo) Transferase (WaaA) and Kdo Kinase (KdkA) of Haemophilus influenzae Are Both Required to Complement a waaAKnockout Mutation of Escherichia coli *

H. Brade, W. Brabetz, S. Müller-Loennies, 2000, The Journal of Biological Chemistry.