I. Campbell

L. Harrison, I. Campbell, R. Bartholomeusz, 1990, Cell differentiation and development : the official journal of the International Society of Developmental Biologists.

A2B5-reactive ganglioside expression is an index of differentiation in rat insulinoma (RIN) cells.

L. Harrison, I. Campbell, R. Bartholomeusz, 1990, Endocrinology.

64,000-Mr Autoantigen in Type I Diabetes: Evidence Against Its Surface Location on Human Islets

L. Harrison, T. Kay, I. Campbell, 1987, Diabetes.

Neuropathogenic actions of cytokines assessed in transgenic mice

I. Campbell, 1995, International Journal of Developmental Neuroscience.

Reactive gliosis as a consequence of interleukin-6 expression in the brain: studies in transgenic mice.

A. Stalder, C. Chiang, I. Campbell, 1994, Developmental neuroscience.

Phenotypic Changes in Smooth Muscle Cells of Human Atherosclerotic Plaques

Julie H. Campbell, I. Campbell, P. Mosse, 1990 .

Experimental Autoimmune Encephalomyelitis on the SJL Mouse: Effect of γδ T Cell Depletion on Chemokine and Chemokine Receptor Expression in the Central Nervous System1

C. Brosnan, I. Campbell, V. Asensio, 2000, The Journal of Immunology.

Experimental Autoimmune Encephalomyelitis on the SJL Mouse: Effect of gd T Cell Depletion on Chemokine and Chemokine Receptor Expression in the Central Nervous System

C. Brosnan, I. Campbell, V. Asensio, 2000 .

Experimental Autoimmune Encephalomyelitis on the SJL Mouse : Effect of gd T Cell Depletion on Chemokine and Chemokine Receptor Expression in the Central Nervous System 1

C. Brosnan, I. Campbell, V. Asensio, 2000 .

Lipocalin 2 in the central nervous system host response to systemic lipopolysaccharide administration

J. P. Ip, I. Campbell, M. Hofer, 2011, Journal of Neuroinflammation.

Astrocyte-Targeted Expression of IFN-α1 Protects Mice from Acute Ocular Herpes Simplex Virus Type 1 Infection

I. Campbell, D. Carr, L. Veress, 1998, The Journal of Immunology.

Interferon-γ: pleiotropic effects on a rat pancreatic beta cell line

L. Harrison, I. Campbell, L. Oxbrow, 1987, Molecular and Cellular Endocrinology.

Leukocyte Infiltration, But Not Neurodegeneration, in the CNS of Transgenic Mice with Astrocyte Production of the CXC Chemokine Ligand 101

M. Carson, J. Demartino, I. Campbell, 2002, The Journal of Immunology.

Mice with Astrocyte Production of the CXC Neurodegeneration, in the CNS of Transgenic Leukocyte Infiltration, But Not

M. Carson, J. Demartino, I. Campbell, 2002 .

Structural and Functional Impact of the Transgenic Expression of Cytokines in the CNS a

I. Campbell, 1998, Annals of the New York Academy of Sciences.

Animal Models of Neurologic Disease

I. Campbell, T. Owens, 2005 .

RNAse protection assays for the simultaneous and semiquantitative analysis of multiple murine matrix metalloproteinase (MMP) and MMP inhibitor mRNAs.

A. Stalder, I. Campbell, A. Pagenstecher, 1997, Journal of immunological methods.

Expression of nitric oxide synthase (NOS)-2 following permanent focal ischemia and the role of nitric oxide in infarct generation in male, female and NOS-2 gene-deficient mice

S. Murphy, I. Campbell, V. Asensio, 1999, Brain Research.

Disruption of the C5a receptor gene fails to protect against experimental allergic encephalomyelitis

S. Barnum, I. Campbell, C. Gerard, 2002, European journal of immunology.

Regulation of murine interferon regulatory factor gene expression in the central nervous system determined by multiprobe RNase protection assay.

I. Campbell, S. Ousman, 2005, Methods in molecular medicine.

Opposing roles for CXCR3 signaling in central nervous system versus ocular inflammation mediated by the astrocyte-targeted production of IL-12.

D. Wakefield, M. Heneka, I. Campbell, 2011, The American journal of pathology.

Chemokines as plurifunctional mediators in the CNS: implications for the pathogenesis of stroke.

I. Campbell, 2004, Ernst Schering Research Foundation workshop.

C10 is a novel chemokine expressed in experimental inflammatory demyelinating disorders that promotes recruitment of macrophages to the central nervous system.

S. Henriksen, S. Lassmann, I. Campbell, 1999, The American journal of pathology.

Binding of Cytoplasmic Islet Cell Antibodies Is Blocked by Human Pancreatic Glycolipid Extracts

G. Eisenbarth, I. Campbell, P. Colman, 1988, Diabetes.

Adult human pancreatic islet cells in tissue culture: function and immunoreactivity.

L. Harrison, I. Campbell, P. Colman, 1985, The Journal of clinical endocrinology and metabolism.

Nesidioblastosis and multifocal pancreatic islet cell hyperplasia in an adult. Clinicopathologic features and in vitro pancreatic studies.

L. Harrison, I. Campbell, P. Colman, 1985, American journal of clinical pathology.

This information is current as Activation Regulate Microglial Integrin Expression and The Extracellular Matrix and Cytokines

I. Campbell, R. Milner, 2003 .

Islet inflammation and hyperplasia induced by the pancreatic islet-specific overexpression of interleukin-6 in transgenic mice.

I. Campbell, M. Oldstone, J. Dockter, 1994, The American journal of pathology.

Cerebral expression of multiple cytokine genes in mice with lymphocytic choriomeningitis.

I. Campbell, M. Oldstone, P. Kemper, 1994, Journal of immunology.

Role of IFN‐γ in an experimental murine model of West Nile virus‐induced seizures

I. Campbell, D. Getts, N. King, 2007 .

Interleukin-6 promotes post-traumatic healing in the central nervous system

I. Campbell, T. Schochet, K. Swartz, 2001, Brain Research.

Lack of specificity of islet cell surface antibodies (ICSA) in IDDM.

L. Harrison, I. Campbell, C. Peterson, 1992, Diabetes research and clinical practice.

IL-17A Promotes Granulocyte Infiltration, Myelin Loss, Microglia Activation, and Behavioral Deficits During Cuprizone-Induced Demyelination

M. Heneka, I. Campbell, J. Zimmermann, 2018, Molecular Neurobiology.

Rapid Upregulation of Interferon-Regulated and Chemokine mRNAs upon Injection of 108 International Units, but Not Lower Doses, of Adenoviral Vectors into the Brain

C. Barcia, P. Lowenstein, I. Campbell, 2006, Journal of Virology.

The effect of metabolites, papaverine, and probenecid on cyclic AMP efflux from isolated rat Islets of Langerhans.

I. Campbell, K. Taylor, 1981, Biochimica et biophysica acta.

Viral Persistence and Chronic Immunopathology in the Adult Central Nervous System following Coxsackievirus Infection during the Neonatal Period

W. Kiosses, I. Campbell, J. Whitton, 2009, Journal of Virology.

A Central Role for CD4+ T Cells and RANTES in Virus-Induced Central Nervous System Inflammation and Demyelination

M. Buchmeier, H. Fox, I. Campbell, 2000, Journal of Virology.

Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain.

C. Heyser, E. Masliah, L. Gold, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Strawberry notch homolog 2 regulates the response to interleukin-6 in the central nervous system

I. Campbell, Magdalena Grill, M. Hofer, 2022, Journal of neuroinflammation.

Liver and brain metallothionein regulation in transgenic mice overexpressing interleukin-6 and in mice carrying a null mutation in the interleukin-6 gene

B. González, H. Bluethmann, I. Campbell, 1999 .

Transgenic expression of interleukin-6 in the central nervous system confers protection against acute herpes simplex virus type-1 infection.

I. Campbell, D. Carr, 1999, Journal of neurovirology.

Localization of Metallothionein-I and -III Expression in the CNS of Transgenic Mice with Astrocyte-Targeted Expression of Interleukin 6

B. González, I. Campbell, Joaquı́n Hernández, 1998, Experimental Neurology.

Transgenic Mice Expressing Cytokines in the CNS as Model Systems for the Study of Inflammatory Neurodegenerative and Demyelinating Disorders

E. Masliah, A. Stalder, I. Campbell, 1998 .

Prion protein (PrP) is not involved in the pathogenesis of spongiform encephalopathy in transgenic mice expressing interleukin-6 in the brain

I. Campbell, H. Powell, P. Castelnau, 1997, Neuroscience Letters.

Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages

I. Campbell, D. Getts, N. King, 2012, Journal of Neuroinflammation.

to CXCR3 Deficiency Due Murine Cerebral Malaria and Protection Chemokine Gene Expression during Fatal

H. Ball, I. Campbell, N. Hunt, 2017 .

Lipopolysaccharide-induced IL-12 expression in the central nervous system and cultured astrocytes and microglia.

F. Bloom, A. Stalder, C. Chiang, 1997, Journal of immunology.

Factor PU.1 Determined by the Myeloid Transcription Microglia of the Central Nervous System Is in g Chemokine Ligand 9 Mediated by IFN-The Cell-Specific Induction of CXC

I. Campbell, M. Hofer, Marcus Müller, 2010 .

The Cell-Specific Induction of CXC

I. Campbell, M. Hofer, P. Manders, 2010 .

Microglia shield the murine brain from damage mediated by the cytokines IL-6 and IFN-α

I. Campbell, M. Hofer, Phillip K. West, 2022, Frontiers in Immunology.

Transgenic models to assess the pathogenic actions of cytokines in the central nervous system

C. Heyser, S. Henriksen, E. Masliah, 1997, Molecular Psychiatry.

Regulation of MHC protein expression in pancreatic beta-cells by interferon-gamma and tumor necrosis factor-alpha.

J. West, L. Harrison, I. Campbell, 1988, Molecular endocrinology.

Effects of adenosine, 2-deoxyadenosine and N6-phenylisopropyladenosine on rat islet function and metabolism.

I. Campbell, K. Taylor, 1982, The Biochemical journal.

Borna Disease Virus Accelerates Inflammation and Disease Associated with Transgenic Expression of Interleukin-12 in the Central Nervous System

I. Campbell, P. Staeheli, A. Pagenstecher, 2002, Journal of Virology.

Ectopic expression of DNA encoding IFN-alpha 1 in the cornea protects mice from herpes simplex virus type 1-induced encephalitis.

I. Campbell, D. Carr, S. Noisakran, 1999, Journal of immunology.

Unforeseen consequences of IL-12 expression in the eye of GFAP-IL12 transgenic mice following herpes simplex virus type 1 infection.

J. Ash, I. Campbell, D. Carr, 2002, DNA and cell biology.

Insulin biosynthesis and its regulation.

I. Campbell, K. Taylor, L. Hellquist, 1982, Clinical science.

Strain specific variation in IFN-γ inducible lymphocyte adhesion to rat brain endothelial cells

J. Greenwood, I. Campbell, P. Luthert, 1998, Journal of Neuroimmunology.

Cytokines Regulate Microglial Adhesion to Laminin and Astrocyte Extracellular Matrix via Protein Kinase C-Dependent Activation of the α6β1 Integrin

I. Campbell, R. Milner, 2002, The Journal of Neuroscience.

Resistance to ocular herpes simplex virus type 1 infection in IL-12 transgenic mice

I. Campbell, D. Carr, Khaldun Al-khatib, 2002, Journal of Neuroimmunology.

TISSUE INHIBITORS OF MATRIX METALLOPROTEINASES, INFLAMMATION, AND THE CENTRAL NERVOUS SYSTEM

I. Campbell, S. Crocker, 2005 .

Characterization of pancreatic T lymphocytes associated with beta cell destruction in the non-obese diabetic (NOD) mouse.

L. Harrison, T. Kay, I. Campbell, 1991, Journal of autoimmunity.

Interferon-gamma induced medulloblastoma in the developing cerebellum.

K. McCarthy, I. Campbell, B. Popko, 2004, Journal of Neuroscience.

The integrin family of cell adhesion molecules has multiple functions within the CNS

Richard Milner, I. Campbell, R. Milner, 2002, Journal of neuroscience research.

Insights from Transgenic and Knockout Mice

I. Campbell, V. Asensio, 2002 .

Insulin receptor expression in the Burkitt lymphoma cells Daudi and Raji.

J. D. Newman, L. Harrison, I. Campbell, 1989, Molecular endocrinology.

IFN-gamma induces islet cell MHC antigens and enhances autoimmune, streptozotocin-induced diabetes in the mouse.

L. Harrison, I. Campbell, L. Oxbrow, 1988, Journal of immunology.

Molecular pathology of type 1 diabetes.

L. Harrison, I. Campbell, Iain L. Campbell, 1990, Molecular biology & medicine.

Cytokine signaling in the brain: Putting a SOCS in it?

I. Campbell, Jianping Wang, 2002, Journal of neuroscience research.

Intercellular adhesion molecule 1 is induced on isolated endocrine islet cells by cytokines but not by reovirus infection.

A. Boyd, D. Wilkinson, L. Harrison, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Expression of the inducible nitric oxide synthase. Correlation with neuropathology and clinical features in mice with lymphocytic choriomeningitis.

C. Chiang, I. Campbell, A. Samimi, 1994, Journal of immunology.

Evidence for IL-6 production by and effects on the pancreatic beta-cell.

L. Harrison, I. Campbell, A. Wilson, 1989, Journal of Immunology.

Reduction in insulitis following administration of IFN-gamma and TNF-alpha in the NOD mouse.

L. Harrison, I. Campbell, L. Oxbrow, 1991, Journal of autoimmunity.

Cytokine and chemokine production in HSV-1 latently infected trigeminal ganglion cell cultures: Effects of hyperthermic stress

W. Halford, I. Campbell, V. Asensio, 1998, Journal of Neuroimmunology.

Regulation of the kinetics of intracerebral chemokine gene expression in murine Toxoplasma encephalitis: Impact of host genetic factors

M. Deckert, I. Campbell, V. Asensio, 2002, Glia.

Simplex Virus Type 1 Infection Protects Mice from Acute Ocular Herpes 1 α Astrocyte-Targeted Expression of IFN-

I. Campbell, D. Carr, L. Veress, 2013 .

Immunoinflammatory diseases of the central nervous system – the tale of two cytokines

I. Campbell, M. Hofer, 2016, British journal of pharmacology.

Type I interferon in neurological disease-the devil from within.

I. Campbell, M. Hofer, 2013, Cytokine & growth factor reviews.

Acute exposure to CXC chemokine ligand 10, but not its chronic astroglial production, alters synaptic plasticity in mouse hippocampal slices

G. Siggins, R. Vlkolinský, I. Campbell, 2004, Journal of Neuroimmunology.

Ly6c+ “inflammatory monocytes” are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis

N. Van Rooijen, I. Campbell, D. Getts, 2008, The Journal of experimental medicine.

Simplex Virus Type 1-Induced Encephalitis in the Cornea Protects Mice from Herpes 1 α Ectopic Expression of DNA Encoding IFN -

I. Campbell, D. Carr, S. Noisakran, 1999 .

Role of metallothionein-III following central nervous system damage

R. Palmiter, I. Campbell, J. Hidalgo, 2003, Neurobiology of Disease.

Pancreatic islet A2B5- and 3G5-reactive gangliosides are markers of differentiation in rat insulinoma cells.

L. Harrison, I. Campbell, R. Bartholomeusz, 1989, Endocrinology.

In vitro techniques for the assessment of neurotoxicity.

H. Tilson, D. Ray, M. Billingsley, 1998, Environmental health perspectives.

MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs.

F. Chisari, G. Sitia, I. Campbell, 2004, The Journal of clinical investigation.

Structural and functional neuropathology in transgenic mice with CNS expression of IFN-α 1 Published on the World Wide Web on 17 March 1999. 1

S. Henriksen, L. Gold, G. Siggins, 1999, Brain Research.

Astrocyte-Targeted Expression of IL-12 Induces Active Cellular Immune Responses in the Central Nervous System and Modulates Experimental Allergic Encephalomyelitis1

A. Stalder, M. Carson, S. Lassmann, 2000, The Journal of Immunology.

Effects of astrocyte‐targeted production of interleukin‐6 in the mouse on the host response to nerve injury

B. Castellano, B. González, I. Campbell, 2014, Glia.

Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration.

F. Bloom, E. Masliah, I. Campbell, 1998, Journal of immunology.

Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

Jin Ma, Huiling Wu, Thomas M. Ashhurst, 2014, Science Translational Medicine.

IFN Regulatory Factor 8 Is a Key Constitutive Determinant of the Morphological and Molecular Properties of Microglia in the CNS

I. Campbell, Rachael L. Terry, N. King, 2012, PloS one.

Role of Tumor Necrosis Factor-α and Interferon-γ as Growth Factors to the Human Fetal β-Cell

A. Simpson, I. Campbell, B. Tuch, 1991 .

Diabetes in transgenic mice resulting from over-expression of class I histocompatibility molecules in pancreatic β cells

G. Morahan, L. Harrison, J. Miller, 1988, Nature.

Increased expression of the beta4 and alpha5 integrin subunits in cerebral blood vessels of transgenic mice chronically producing the pro-inflammatory cytokines IL-6 or IFN-alpha in the central nervous system.

I. Campbell, R. Milner, 2006, Molecular and cellular neurosciences.

Response of Glia, Mast Cells and the Blood Brain Barrier, in Transgenic Mice Expressing Interleukin‐3 in Astrocytes, an Experimental Model for CNS Demyelination

E. Masliah, C. Chiang, I. Campbell, 1999, Brain pathology.

Macrophage/microglial-mediated primary demyelination and motor disease induced by the central nervous system production of interleukin-3 in transgenic mice.

L. Gold, C. Chiang, I. Campbell, 1996, The Journal of clinical investigation.

IFN-γ-Induced Chemokines Synergize with Pertussis Toxin to Promote T Cell Entry to the Central Nervous System1

J. Gauldie, I. Campbell, T. Owens, 2007, The Journal of Immunology.

PLX5622 Reduces Disease Severity in Lethal CNS Infection by Off-Target Inhibition of Peripheral Inflammatory Monocyte Production

I. Campbell, L. Macia, N. King, 2022, Frontiers in Immunology.

High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory disease

I. Campbell, N. King, T. Ashhurst, 2021, Journal of neuroinflammation.

Alterations in microglial phenotype and hippocampal neuronal function in transgenic mice with astrocyte-targeted production of interleukin-10

J. Delgado-García, A. Gruart, B. Castellano, 2015, Brain, Behavior, and Immunity.

Reduced cuprizone-induced cerebellar demyelination in mice with astrocyte-targeted production of IL-6 is associated with chronically activated, but less responsive microglia

B. Castellano, B. González, I. Campbell, 2017, Journal of Neuroimmunology.

IL-17A Promotes Granulocyte Infiltration, Myelin Loss, Microglia Activation, and Behavioral Deficits During Cuprizone-Induced Demyelination

M. Heneka, I. Campbell, J. Zimmermann, 2017, Molecular Neurobiology.

Reactivity to Human Islets and Fetal Pig Proislets by Peripheral Blood Mononuclear Cells From Subjects With Preclinical and Clinical Insulin-Dependent Diabetes

I. Campbell, T. Loudovaris, P. Colman, 1991, Diabetes.

IFN-gamma and tumor necrosis factor-alpha. Cytotoxicity to murine islets of Langerhans.

L. Harrison, I. Campbell, A. Iscaro, 1988, Journal of immunology.

Microglia responses to interleukin‐6 and type I interferons in neuroinflammatory disease

I. Campbell, M. Hofer, Phillip K. West, 2019, Glia.

The stromal cell–derived factor-1α/CXCR4 ligand–receptor axis is critical for progenitor survival and migration in the pancreas

N. Sarvetnick, A. Kayali, I. Campbell, 2003, The Journal of cell biology.

Transgenic mice and cytokine actions in the brain: bridging the gap between structural and functional neuropathology 1 Published on the World Wide Web on 21 October 1997. 1

I. Campbell, 1998, Brain Research Reviews.

Transgenic models to assess the neuropathogenic potential of HIV-1 proteins and cytokines.

L. Mucke, E. Masliah, I. Campbell, 1995, Current topics in microbiology and immunology.

Deletion of the Complement Anaphylatoxin C3a Receptor Attenuates, Whereas Ectopic Expression of C3a in the Brain Exacerbates, Experimental Autoimmune Encephalomyelitis1

S. Barnum, R. Ames, I. Campbell, 2004, The Journal of Immunology.

Regulation of signal transducer and activator of transcription and suppressor of cytokine-signaling gene expression in the brain of mice with astrocyte-targeted production of interleukin-12 or experimental autoimmune encephalomyelitis.

I. Campbell, A. Pagenstecher, C. Kincaid, 2002, The American journal of pathology.

NF-κB activation is inhibited in human pulmonary epithelial cells transfected with α-melanocyte-stimulating hormone vector

J. M. Lipton, I. Campbell, T. Ichiyama, 2000, Peptides.

Chronic exposure to IL-6 induces a desensitized phenotype of the microglia

B. Castellano, B. González, I. Campbell, 2021, Journal of neuroinflammation.

Altered physiology of purkinje neurons in cerebellar slices from transgenic mice with chronic central nervous system expression of interleukin-6

D. Gruol, T. Nelson, I. Campbell, 1999, Neuroscience.

Coordinated Regulation and Widespread Cellular Expression of Interferon-Stimulated Genes (ISG) ISG-49, ISG-54, and ISG-56 in the Central Nervous System after Infection with Distinct Viruses

I. Campbell, G. Sen, S. Ousman, 2006, Journal of Virology.

Chemokines in the CNS: plurifunctional mediators in diverse states

I. Campbell, V. Asensio, 1999, Trends in Neurosciences.

The Cell-Specific Induction of CXC Chemokine Ligand 9 Mediated by IFN-γ in Microglia of the Central Nervous System Is Determined by the Myeloid Transcription Factor PU.1

I. Campbell, Wen Li, M. Hofer, 2010, The Journal of Immunology.

Chemokine Actions in the CNS: Insights from Transgenic Mice

I. Campbell, M. Müller, 2008, Central Nervous System Diseases and Inflammation.

Regulatory T Cells in the Central Nervous Parenchymal Distribution of Effector and Encephalomyelitis by Controlling the Experimental Autoimmune CXCR 3 Signaling Reduces the Severity of

I. Campbell, D. Getts, N. King, 2007 .

Trans-Signaling Is a Dominant Mechanism for the Pathogenic Actions of Interleukin-6 in the Brain

Juan Hidalgo, Stefan Rose-John, J. Scheller, 2014, The Journal of Neuroscience.

RNA-Dependent Protein Kinase Is Required for Alpha-1 Interferon Transgene-Induced Resistance to Genital Herpes Simplex Virus Type 2

B. Williams, R. Silverman, I. Campbell, 2005, Journal of Virology.

Reduced Hippocampal Neurogenesis in Adult Transgenic Mice with Chronic Astrocytic Production of Interleukin-6

F. Gage, P. Sawchenko, I. Campbell, 2002, The Journal of Neuroscience.

Persistent macrophage/microglial activation and myelin disruption after experimental autoimmune encephalomyelitis in tissue inhibitor of metalloproteinase-1-deficient mice.

R. Frausto, I. Campbell, J. Whitton, 2006, The American journal of pathology.

Regulation of matrix metalloproteinases and their inhibitor genes in lipopolysaccharide-induced endotoxemia in mice.

A. Stalder, I. Campbell, B. Volk, 2000, The American journal of pathology.

Modulation of Hypothalamic–Pituitary–Adrenal Function by Transgenic Expression of Interleukin-6 in the CNS of Mice

F E Bloom, F. Bloom, I. Campbell, 1997, The Journal of Neuroscience.

Activation of cerebral cytokine gene expression and its correlation with onset of reactive astrocyte and acute-phase response gene expression in scrapie

I. Campbell, M. Oldstone, M. Eddleston, 1994, Journal of virology.

Islet-specific Th1, but not Th2, cells secrete multiple chemokines and promote rapid induction of autoimmune diabetes.

N. Sarvetnick, I. Campbell, L. Bradley, 1999, Journal of immunology.

IRF9 Prevents CD8+ T Cell Exhaustion in an Extrinsic Manner during Acute Lymphocytic Choriomeningitis Virus Infection

M. Huber, T. Strecker, H. Raifer, 2017, Journal of Virology.

Inflammatory monocytes and the pathogenesis of viral encephalitis

I. Campbell, D. Getts, N. King, 2012, Journal of Neuroinflammation.

Structural and functional neuropathology in transgenic mice with CNS expression of IFN-alpha.

S. Henriksen, L. Gold, G. Siggins, 1999, Brain research.

Induction of Autoimmune Diabetes Multiple Chemokines and Promote Rapid Islet-Specific Th 1 , But Not Th 2 , Cells Secrete

N. Sarvetnick, I. Campbell, L. Bradley, 1999 .

Chemokines and the inflammatory response to viral infection in the central nervous system with a focus on lymphocytic choriomeningitis virus.

I. Campbell, V. Asensio, C. Kincaid, 1999, Journal of neurovirology.

Induction of atypical EAE mediated by transgenic production of IL‐6 in astrocytes in the absence of systemic IL‐6

Agustina Garcı́a, I. Campbell, A. Quintana, 2013, Glia.

A novel phosphoproteomic landscape evoked in response to type I interferon in the brain and in glial cells

Melanie Y. White, S. Cordwell, I. Campbell, 2021, Journal of neuroinflammation.

Systemic interferon-α regulates interferon-stimulated genes in the central nervous system

I. Campbell, H. Zhang, J. Wang, 2008, Molecular Psychiatry.

The cytokines interleukin-6 and interferon-α induce distinct microglia phenotypes

Boris Guennewig, I. Campbell, O. Butovsky, 2022, Journal of neuroinflammation.

Type I interferon-regulated gene expression and signaling in murine mixed glial cells lacking signal transducers and activators of transcription 1 or 2 or interferon regulatory factor 9*

I. Campbell, G. Denyer, D. Hancock, 2017, The Journal of Biological Chemistry.

STAT1 deficiency unexpectedly and markedly exacerbates the pathophysiological actions of IFN-α in the central nervous system

Iain L. Campbell, Robert D. Schreiber, R. Schreiber, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Autocrine α‐melanocyte‐stimulating hormone inhibits NF‐κB activation in human glioma

J. M. Lipton, A. Catania, I. Campbell, 1999 .

Microglia have a more extensive and divergent response to interferon‐α compared with astrocytes

I. Campbell, G. Denyer, Wen Li, 2018, Glia.

Innate STAT1-Dependent Genomic Response of Neurons to the Antiviral Cytokine Alpha Interferon

I. Campbell, Jianping Wang, 2005, Journal of Virology.

Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN-α–stimulated STAT2-independent production of IFN-γ in the brain

C. Schindler, I. Campbell, Jianping Wang, 2003 .

Minimal role for STAT1 in interleukin‐6 signaling and actions in the murine brain

I. Campbell, E. Sanz, M. Unzeta, 2008, Glia.

IFN-alpha1 plasmid construct affords protection against HSV-1 infection in transfected L929 fibroblasts.

I. Campbell, D. Carr, S. Noisakran, 2000, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Late-onset chronic inflammatory encephalopathy in immune-competent and severe combined immune-deficient (SCID) mice with astrocyte-targeted expression of tumor necrosis factor.

E. Masliah, A. Stalder, M. Carson, 1998, The American journal of pathology.

Transgenic models for cytokine-induced neurological disease.

I. Campbell, A. Pagenstecher, Iain L Campbell, 2010, Biochimica et biophysica acta.

Inducible production of interferon-γ in the developing brain causes cerebellar dysplasia with activation of the Sonic hedgehog pathway

I. Campbell, B. Popko, Jianping Wang, 2004, Molecular and Cellular Neuroscience.

Microglia stimulate naive T‐cell differentiation without stimulating T‐cell proliferation

J. Sutcliffe, M. Carson, I. Campbell, 1999, Journal of neuroscience research.

MHC molecules and beta-cell destruction. Immune and nonimmune mechanisms.

L. Harrison, J. Miller, I. Campbell, 1989, Diabetes.

IRF7-Dependent Type I Interferon Production Induces Lethal Immune-Mediated Disease in STAT1 Knockout Mice Infected with Lymphocytic Choriomeningitis Virus

I. Campbell, Wen Li, M. Hofer, 2014, Journal of Virology.

Pertussis Toxin to Promote T Cell Entry to-Induced Chemokines Synergize with γ IFN-Gauldie and Trevor

J. Gauldie, I. Campbell, T. Owens, 2007 .

Interferon- (cid:1) Induced Medulloblastoma in the Developing Cerebellum

K. McCarthy, I. Campbell, B. Popko, 2022 .

DNA Immunization with Minigenes: Low Frequency of Memory Cytotoxic T Lymphocytes and Inefficient Antiviral Protection Are Rectified by Ubiquitination

Fernando Rodriguez, Iain L. Campbell, Jie Zhang, 1998, Journal of Virology.

The M22 antibody identifies highly activated reactive astrocytes responding to central nervous system disease

I. Campbell, J. C. de la Torre, M. Oldstone, 1996, Acta Neuropathologica.

Interferon-Independent, Human Immunodeficiency Virus Type 1 gp120-Mediated Induction of CXCL10/IP-10 Gene Expression by Astrocytes In Vivo and In Vitro

H. Fox, I. Campbell, R. Milner, 2001, Journal of Virology.

A role for apoE in regulating the levels of alpha-1-antichymotrypsin in the aging mouse brain and in Alzheimer's disease.

J. Gilbert, E. Masliah, M. Mallory, 1999, The American journal of pathology.

Transcriptional Activation following Cerebral Ischemia in Mice of a Promoter-deleted Nitric Oxide Synthase-2 Gene*

J. Mudgett, I. Campbell, Sean Murphy, 1999, The Journal of Biological Chemistry.

Chronic Neuroinflammation in Alzheimer's Disease: New Perspectives on Animal Models and Promising Candidate Drugs

I. Campbell, J. Aldrich-Wright, G. Münch, 2014, BioMed research international.

Cytokine-mediated inflammation and signaling in the intact central nervous system.

I. Campbell, 2001, Progress in brain research.

Interferon-gamma induces the expression of HLA-A,B,C but not HLA-DR on human pancreatic beta-cells.

L. Harrison, I. Campbell, P. Colman, 1986, The Journal of clinical endocrinology and metabolism.

Community Dynamics in the Mouse Gut Microbiota: A Possible Role for IRF9-Regulated Genes in Community Homeostasis

A. Holmes, I. Campbell, M. Hofer, 2010, PloS one.

The role of advanced glycation end products in retinal microvascular leukostasis.

Yuichi Kaji, Alan W. Stitt, V. Poulaki, 2003, Investigative ophthalmology & visual science.

Altered Central Nervous System Cytokine-Growth Factor Expression Profiles and Angiogenesis in Metallothionein-I+II Deficient Mice

I. Campbell, J. Hidalgo, M. Penkowa, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Tumor necrosis factor‐α inhibits seizures in mice via p75 receptors

A. Vezzani, J. Peschon, I. Campbell, 2005 .

Strawberry notch homolog 2 is a novel inflammatory response factor predominantly but not exclusively expressed by astrocytes in the central nervous system

Stefan Rose-John, S. Rose-John, I. Campbell, 2015, Glia.

Mice Deficient in STAT1 but Not STAT2 or IRF9 Develop a Lethal CD4+ T-Cell-Mediated Disease following Infection with Lymphocytic Choriomeningitis Virus

I. Campbell, Rachael L. Terry, N. King, 2012, Journal of Virology.

Extracellular aggregated Cu/Zn superoxide dismutase activates microglia to give a cytotoxic phenotype

I. Campbell, J. Yerbury, Wen Li, 2013, Glia.

Cannabinoids and interleukin-6 enhance the response to NMDA in developing CNS neurons.

J. G. Netzeband, K. L. Parsons, D. Gruol, 1996, Advances in experimental medicine and biology.

Reduced long-term potentiation in the dentate gyrus of transgenic mice with cerebral overexpression of interleukin-6

G. Siggins, I. Campbell, S. Madamba, 1995, Neuroscience Letters.

Cytokines and chemokines as mediators of protection and injury in the central nervous system assessed in transgenic mice.

I. Campbell, V. Asensio, J. Wang, 2002, Current topics in microbiology and immunology.

The Type I Interferon-α Mediates a More Severe Neurological Disease in the Absence of the Canonical Signaling Molecule Interferon Regulatory Factor 9

I. Campbell, Wen Li, M. Hofer, 2010, The Journal of Neuroscience.

Factors controlling T-cell migration across rat cerebral endothelium in vitro

J. Greenwood, I. Campbell, G. Pryce, 1997, Journal of Neuroimmunology.

Effect of astrocyte‐targeted production of IL‐6 on traumatic brain injury and its impact on the cortical transcriptome

F. Nielsen, I. Campbell, A. Quintana, 2008, Developmental neurobiology.

Induction of acute phase gene expression by brain irradiation.

H. Withers, J. Hong, C. Chiang, 1995, International journal of radiation oncology, biology, physics.

CNS-Specific Synthesis of Interleukin 23 Induces a Progressive Cerebellar Ataxia and the Accumulation of Both T and B Cells in the Brain: Characterization of a Novel Transgenic Mouse Model

A. Becker, M. Heneka, I. Campbell, 2019, Molecular Neurobiology.

Metallothionein‐I Overexpression Decreases Brain Pathology in Transgenic Mice with Astrocyte‐Targeted Expression of Interleukin‐6

N. Lago, I. Campbell, J. Hidalgo, 2003, Journal of neuropathology and experimental neurology.

Allergic Encephalomyelitis the Central Nervous System and Modulates inInduces Active Cellular Immune Responses Astrocyte-Targeted Expression of IL-12

A. Stalder, M. Carson, S. Lassmann, 2000 .

Systemic interferon-alpha regulates interferon-stimulated genes in the central nervous system.

I. Campbell, H. Zhang, J. Wang, 2008, Molecular psychiatry.

Contribution of STAT1 to innate and adaptive immunity during type I interferon-mediated lethal virus infection

I. Campbell, N. King, T. Ashhurst, 2020, PLoS pathogens.

Site-Specific Production of IL-6 in the Central Nervous System Retargets and Enhances the Inflammatory Response in Experimental Autoimmune Encephalomyelitis1

R. Frausto, I. Campbell, A. Quintana, 2009, The Journal of Immunology.

Induction of the genes for Cxcl9 and Cxcl10 is dependent on IFN‐γ but shows differential cellular expression in experimental autoimmune encephalomyelitis and by astrocytes and microglia in vitro

Marcus Müller, I. Campbell, Sally L. Carter, 2007, Glia.

Effects of glucose and D-3-hydroxybutyrate on human pancreatic islet cell function.

I. Campbell, C. Rhodes, T. M. Szopa, 1985, Clinical science.

Tumor necrosis factor-alpha inhibits seizures in mice via p75 receptors.

Annamaria Vezzani, A. Vezzani, J. Peschon, 2005, Annals of neurology.

The inflammatory milieu associated with conjunctivalized cornea and its alteration with IL-1 RA gene therapy.

D. Archer, A. Adamis, I. Campbell, 2002, Investigative ophthalmology & visual science.

Dynamic Regulation of α- and β-Chemokine Expression in the Central Nervous System During Mouse Hepatitis Virus-Induced Demyelinating Disease

M. Buchmeier, I. Campbell, V. Asensio, 1998, The Journal of Immunology.

Elevated complement C5a receptor expression on neurons and glia in astrocyte‐targeted interleukin‐3 transgenic mice

S. Barnum, I. Campbell, P. M. Paradisis, 1998, Glia.

CNS-Targeted Production of IL-17A Induces Glial Activation, Microvascular Pathology and Enhances the Neuroinflammatory Response to Systemic Endotoxemia

M. Heneka, I. Campbell, M. Hofer, 2013, PloS one.

Diverging mechanisms for TNF‐α receptors in normal mouse brains and in functional recovery after injury: From gene to behavior

F. Nielsen, I. Campbell, A. Quintana, 2007, Journal of neuroscience research.

Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages

I. Campbell, D. Getts, N. King, 2012, Journal of Neuroinflammation.

Role of IFN-gamma in an experimental murine model of West Nile virus-induced seizures.

I. Campbell, D. Getts, N. King, 2007, Journal of neurochemistry.

High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory disease

I. Campbell, T. Ashhurst, M. Hofer, 2021, Journal of Neuroinflammation.

Autoimmune Enhances the Inflammatory Response in Central Nervous System Retargets and Site-Specific Production of IL-6 in the

R. Frausto, I. Campbell, A. Quintana, 2009 .

Transgenic expression of TNF by astrocytes increases mechanical allodynia in a mouse neuropathy model

A. Stalder, I. Campbell, J. Deleo, 2000, Neuroreport.

The Bacteriostatic Protein Lipocalin 2 Is Induced in the Central Nervous System of Mice with West Nile Virus Encephalitis

I. Campbell, D. Getts, N. King, 2013, Journal of Virology.

Analysis of IL‐6/gp130 family receptor expression reveals that in contrast to astroglia, microglia lack the oncostatin M receptor and functional responses to oncostatin M

S. Rose-John, R. Frausto, I. Campbell, 2015, Glia.

Herpes simplex virus type 1 induction of chemokine production is unrelated to viral load in the cornea but not in the nervous system.

I. Campbell, D. Carr, 2006, Viral immunology.

A Modulatory Role for Advanced Glycation End-Products (AGEs) in Retinal Microvascular Leukostasis

Alan W. Stitt, V. Poulaki, D. Archer, 2002 .

Experimental Autoimmune Expression of C3a in the Brain Exacerbates, C3a Receptor Attenuates, Whereas Ectopic Deletion of the Complement Anaphylatoxin

Robert S. Ames, Scott R. Barnum, Laura Boos, 2013 .

Encephalomyelitis Experimental Autoimmune Expression of C 3 a in the Brain Exacerbates , C 3 a Receptor Attenuates , Whereas Ectopic Deletion of the Complement Anaphylatoxin and

S. Barnum, R. Ames, I. Campbell, 2004 .

IFN-gamma-induced chemokines synergize with pertussis toxin to promote T cell entry to the central nervous system.

J. Gauldie, I. Campbell, T. Owens, 2007, Journal of immunology.

Increased lethality but decreased encephalitis in IRF8-deficient mice following West Nile Virus infection (154.1)

I. Campbell, Rachael L. Terry, N. King, 2011, Journal of Immunology.

Site-specific hippocampal pathophysiology due to cerebral overexpression of interleukin-6 in transgenic mice

S. Henriksen, I. Campbell, S. Steffensen, 1994, Brain Research.

Expression of C5a in the brain does not exacerbate experimental autoimmune encephalomyelitis

S. Barnum, J. Ting, I. Campbell, 2005, Neuroscience Letters.

Interferon-γ Induced Medulloblastoma in the Developing Cerebellum

K. McCarthy, I. Campbell, B. Popko, 2004 .

Altered tissue distribution of viral replication and T cell spreading is pivotal in the protection against fatal lymphocytic choriomeningitis in mice after neutralization of IFN-alpha/beta.

A. Stalder, I. Campbell, J. Zhang, 1994, Journal of immunology.

Physiological and behavioral effects of methamphetamine in a mouse model of endotoxemia: a preliminary study

S. Henriksen, J. Criado, Janai R. Carr, 2004, Pharmacology Biochemistry and Behavior.

Transgenic models for cytokine-induced neurological disease.

I. Campbell, A. Pagenstecher, M. Hofer, 2010, Biochimica et biophysica acta.

Research report Interleukin-6 promotes post-traumatic healing in the central nervous

I. Campbell, T. Schochet, K. Swartz, 2001 .

CNS-Specific Synthesis of Interleukin 23 Induces a Progressive Cerebellar Ataxia and the Accumulation of Both T and B Cells in the Brain: Characterization of a Novel Transgenic Mouse Model

A. Becker, M. Heneka, I. Campbell, 2019, Molecular Neurobiology.

Defective Inflammatory Monocyte Development in IRF8-Deficient Mice Abrogates Migration to the West Nile Virus-Infected Brain

I. Campbell, D. Getts, M. T. Getts, 2014, Journal of Innate Immunity.

Type I interferon in neurological disease-the devil from within.

I. Campbell, M. Hofer, 2013, Cytokine & growth factor reviews.

Encephalomyelitis Experimental Autoimmune Enhances the Inflammatory Response in Central Nervous System Retargets and Site-Specific Production of IL-6 in the

R. Frausto, I. Campbell, E. Sanz, 2009 .

Interferon-γ Enhances the Expression of the Major Histocompatibility Class I Antigens on Mouse Pancreatic Beta Cells

G. Wong, L. Harrison, J. Schrader, 1985, Diabetes.

Type I interferon-regulated gene expression and signaling in murine mixed glial cells lacking signal transducers and activators of transcription 1 or 2 or interferon regulatory factor 9*

I. Campbell, G. Denyer, D. Hancock, 2017, The Journal of Biological Chemistry.

The relation of the endocrine system to the regulation of calcium metabolism.

C. W. Turner, I. Campbell, 1942 .

Binding of Cytoplasmic Islet Cell Antibodies Is Blocked by Human Pancreatic Glycolipid Extracts

G. Eisenbarth, I. Campbell, P. Colman, 1988, Diabetes.

Matrix metalloproteinases and their inhibitors in the nervous system: the good, the bad and the enigmatic

I. Campbell, A. Pagenstecher, 1999, Trends in Neurosciences.

A polymorphism in the mouse crg-2/IP-10 gene complicates chemokine gene expression analysis using a commercial ribonuclease protection assay.

I. Campbell, P. Staeheli, V. Asensio, 2000, Journal of immunological methods.

Autocrine alpha-melanocyte-stimulating hormone inhibits NF-kappaB activation in human glioma.

J. M. Lipton, A. Catania, I. Campbell, 1999, Journal of neuroscience research.

Analysis of the Cerebral Transcriptome in Mice Subjected to Traumatic Brain Injury: Importance of IL-6

I. Campbell, J. Hidalgo, M. Penkowa, 2007, Neuroimmunomodulation.