D. Handley

发表

Endothelium and Regulation of Coagulation

H. Gerlach, D. Stern, P. Nawroth, 1991, Diabetes Care.

A coagulation pathway on bovine aortic segments leading to generation of Factor Xa and thrombin.

W. Kisiel, M. Drillings, D. Stern, 1984, The Journal of clinical investigation.

Dose-Response Evaluation of Levalbuterol Versus Racemic Albuterol in Patients with Asthma

D. Handley, D. Tinkelman, J. Caron, 2000, The Journal of asthma : official journal of the Association for the Care of Asthma.

Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity.

D. Stern, P. Nawroth, D. Handley, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Suppression of rat carotid lesion development by the calcium channel blocker PN 200-110.

D. Handley, R. Saunders, R. G. Van Valen, 1986, The American journal of pathology.

Subcellular distribution of marker enzymes in cells of a minute fungus, Fusidium sp. 100-3

D. Handley, B. K. Ghosh, 1980, Journal of bacteriology.

New millennium bronchodilators for asthma: single-isomer beta agonists

D. Handley, M. E. Snider, A. Anderson, 2000, Current opinion in pulmonary medicine.

Advancement of the Third Generation of Antihistamines

D. Handley, 1999 .

Therapeutic advantages of third generation antihistamines.

D. Handley, A. J. Higgins, A. Magnetti, 1998, Expert opinion on investigational drugs.

Factor-IX deficiency in the nephrotic syndrome.

D. Handley, J. Lawrence, 1967, Lancet.

Platelet-derived growth factor labeled to colloidal gold for use as a mitogenic receptor probe.

D. Handley, L. Witte, 1984, European journal of cell biology.

Cellular processing of bovine factors X and Xa by cultured bovine aortic endothelial cells

W. Kisiel, D. Stern, P. Nawroth, 1985, The Journal of experimental medicine.

Endothelial Cell Regulation of Coagulation

D. Stern, P. Nawroth, D. Handley, 1998 .

Biosynthetic Inhibitors and Receptor Antagonists to Platelet Activating Factor

D. Handley, 1997 .

Vascular responses of platelet-activating factor in the Cebus apella primate and inhibitory profiles of antagonists SRI 63-072 and SRI 63-119.

D. Handley, R. Saunders, R. G. Van Valen, 1986, Immunopharmacology.

Pharmacological approaches and strategies for therapeutic modulation of fibrinogen.

T. Hughes, D. Handley, Dean A. Handley, 1997, Thrombosis research.

Effect of platelet activating factor on endothelial permeability to plasma macromolecules.

D. Handley, C. Arbeeny, R. Saunders, 1984, Immunopharmacology.

Determinants of the uptake of very low density lipoprotein remnants by the perfused rat liver.

D. Handley, H. Eder, C. Arbeeny, 1987, Metabolism: clinical and experimental.

Hepatic binding and internalization of low density lipoprotein-gold conjugates in rats treated with 17 alpha-ethinylestradiol

D. Handley, H. Eder, C. Arbeeny, 1981, The Journal of cell biology.

7 – Preparation and Application of Lipoprotein–Gold Complex

D. Handley, C. Arbeeny, 1989 .

Haemolytic Anaemia of Mechanical Origin after Open Heart Surgery

S. Lewis, W. Cleland, D. Handley, 1961, Thorax.

In Vitro and In Vivo Pharmacological Profiles of the PAF Receptor Antagonist SRI 63-675

J. Tomesch, D. Handley, R. Saunders, 1987, Thrombosis and Haemostasis.

An endothelial cell-dependent pathway of coagulation.

W. Kisiel, D. Stern, P. Nawroth, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition and reversal of endotoxin-, aggregated IgG- and paf-induced hypotension in the rat by SRI 63-072, a paf receptor antagonist.

D. Handley, R. Saunders, R. G. Van Valen, 1986, Immunopharmacology.

Biological actions of formoterol isomers.

J. Benovic, D. Handley, C. Senanayake, 2002, Pulmonary pharmacology & therapeutics.

Effects of S-salbutamol on human isolated bronchus.

E. Chilvers, D. Handley, I. Chapman, 1998, Pulmonary pharmacology & therapeutics.

Effect of enantiomeric forms of albuterol on stimulated secretion of granular protein from human eosinophils.

R. Naclerio, F. Baroody, D. Handley, 1997, Pulmonary pharmacology & therapeutics.

Effects ofRS-albuterol on the development of antigen-mediated airway hyperreactivity in guinea pigs

D. Handley, A. Jafarian, D. Biggs, 1996, Clinical reviews in allergy & immunology.

The pursuit of precision pharmaceuticals: divergent effects of beta2 agonist isomers.

D. Handley, J. Morley, 1998, Expert opinion on investigational drugs.

Sympathomimetic enantiomers and asthma.

D. Handley, J. Morley, J. Mccullough, 1998, Chirality.

The asthma-like pharmacology and toxicology of (S)-isomers of β agonists☆☆☆

D. Handley, 1999 .

Preclinical and clinical pharmacology of platelet‐activating factor receptor antagonists

D. Handley, 1990, Medicinal research reviews.

Prevention of non‐specific airway hyperreactivity after allergen challenge in guinea‐pigs by the PAF receptor antagonist SDZ 64–412

D. Handley, A. M. Havill, Ronald G. Valen, 1990, British journal of pharmacology.

Colloidal Gold: A Pluripotent Receptor Probe

D. Handley, S. Chien, 1983, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Sinusoidal endothelial endocytosis of low density lipoprotein-gold conjugates in perfused livers of ethinyl-estradiol treated rats.

D. Handley, C. Arbeeny, S. Chien, 1983, European journal of cell biology.

Induction by aerosol allergen of sustained and nonspecific IgE-mediated airway hyperreactivity in the guinea pig

D. Handley, A. M. Havill, J. Deleo, 1992, Agents and Actions.

Platelet activating factor and inflammation in atherogenesis: Targets for drug development

D. Handley, R. Saunders, Dean A. Handley, 1986 .

Antitumor activity of SRI 62-834, a cyclic ether analog of ET-18-OCH3

D. Handley, G. M. Nemecek, C. Winslow, 1987, Lipids.

Evidence for distinct systemic extravasation effects of platelet activating factor, leukotrienes B4, C4, D4 and histamine in the guinea pig.

C. Farley, D. Handley, R. Deacon, 1986, Prostaglandins, leukotrienes, and medicine.

Biological properties of the antagonist SRI 63-441 in the PAF and endotoxin models of hypotension in the rat and dog.

J. Tomesch, J. Jaffe, D. Handley, 1987, Immunopharmacology.

Inhibition by SRI 63-072 and SRI 63-119 of PAF-acether and immune complex effects in the guinea pig.

D. Handley, R. Saunders, R. Anderson, 1987, European journal of pharmacology.

Evidence for a direct effect on vascular permeability of platelet-activating factor induced hemoconcentration in the guinea pig.

D. Handley, R. Saunders, M. L. Lee, 1985, Thrombosis and haemostasis.

Evaluation of Dose and Route Effects of Platelet Activating Factor-Induced Extravasation in the Guinea Pig

D. Handley, R. Saunders, R. G. Van Valen, 1984, Thrombosis and Haemostasis.

Colloidal gold--low density lipoprotein conjugates as membrane receptor probes.

D. Handley, C. Arbeeny, S. Chien, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Current approaches to inhibition of proliferation in atherosclerosis

D. Handley, Dean A. Handley, 1985 .

Inhibition of PAF-induced systemic responses in the rat, guinea pig, dog and primate by the receptor antagonist SRI 63-441.

J. Tomesch, D. Handley, R. Saunders, 1986, Thrombosis and haemostasis.

Activation of the coagulation mechanism on tumor necrosis factor-stimulated cultured endothelial cells and their extracellular matrix. The role of flow and factor IX/IXa.

J. Sixma, P. D. de Groot, D. Stern, 1991, The Journal of biological chemistry.

The asthma-like pharmacology and toxicology of (S)-isomers of beta agonists.

D. Handley, 1999, The Journal of allergy and clinical immunology.

Effects of Platelet-Activating Factor on Leukocyte Adhesion in the Guinea Pig Aorta

D. Handley, R. Saunders, M. Melden, 1985 .

Experiences in the Use of Fibrinolytic Agents in Behcet's Syndrome *

D. Handley, J. Kirk, 1972, The Australasian journal of dermatology.

Biological effects of the orally active platelet activating factor receptor antagonist SDZ 64-412.

D. Handley, R. Saunders, W. Houlihan, 1988, The Journal of pharmacology and experimental therapeutics.

Endothelium and regulation of coagulation.

H. Gerlach, D. Stern, P. Nawroth, 1991, Diabetes care.

Ultrastructure of hepatic cholesterol crystals in the hypercholesterolemic - diabetic rat.

D. Handley, C. Arbeeny, S. Chien, 1983, Pathology, research and practice.

Further Experience with a Concentrate Containing Human Antihaemophilic Factor *

R. G. Macfarlane, P. Wolf, D. Handley, 1963 .

Colloidal gold labeling studies related to vascular and endothelial function, hemostasis and receptor-mediated processing of plasma macromolecules.

D. Handley, S. Chien, 1987, European journal of cell biology.

2 – Methods for Synthesis of Colloidal Gold

D. Handley, Dean A. Handley, 1989 .

Membrane-bound lipoprotein lipase on human monocyte-derived macrophages: localization by immunocolloidal gold technique.

I. Goldberg, D. Handley, J. Cornicelli, 1988, Biochimica et biophysica acta.

Ultrastructural studies of endothelial and platelet receptor binding of thrombin-colloidal gold probes.

D. Handley, S. Chien, 1986, European journal of cell biology.

THE SURGICAL TREATMENT OF HAEMOPHILIC BLOOD CYSTS

D. Handley, C. Webster, M. Hall, 1962 .

The Preparation and Assay of a Christmas‐Factor (Factor IX) Concentrate and its Use in the Treatment of Two Patients

R. G. Macfarlane, D. Handley, R. Biggs, 1961 .

SURGICAL TREATMENT OF DUODENAL ULCERATION IN TWO HÆMOPHILIACS

D. Handley, N. Painter, M. Hall, 1961 .

Antitumor activity of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinolines.

D. Handley, S. Cheon, V. Parrino, 1995, Journal of medicinal chemistry.

Structural modification of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline platelet activating factor receptor antagonists.

D. Handley, S. Cheon, V. Parrino, 1993, Journal of medicinal chemistry.

Strains of Fusidia which can be mistaken for Actinomycetes.

D. Handley, B. K. Ghosh, H. Lechevalier, 1977, Mycologia.

Terbinafine inhibits the mitogenic response to platelet-derived growth factor in vitro and neointimal proliferation in vivo.

D. Handley, G. M. Nemecek, A. Stütz, 1989, The Journal of pharmacology and experimental therapeutics.

Experimental therapeutics and clinical studies in (re)stenosis.

D. Handley, 1995, Micron.

Single‐Isomer β‐Agonists

D. Handley, 2001 .

Tumor necrosis factor/cachectin-induced intravascular fibrin formation in meth A fibrosarcomas

H. Gerlach, R. D. de Waal, D. Stern, 1988, The Journal of experimental medicine.

Platelet function in essential thrombocythaemia

D. Handley, S. Watts, R. Pembrey, 1975 .

Preclinical Enantioselective Pharmacology of (R)‐ and (S)‐ Ketorolac

J. McCray, D. Handley, P. Cervoni, 1998, Journal of clinical pharmacology.

Vesicle distribution in the arterial endothelium determined with ruthenium red as an extracellular marker.

D. Handley, S. Chien, L. Laufer, 1982, Journal of ultrastructure research.

Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1

L. Chess, D. Stern, P. Nawroth, 1986, The Journal of experimental medicine.

Interaction of antithrombin III with bovine aortic segments. Role of heparin in binding and enhanced anticoagulant activity.

W. Kisiel, J. Marcum, D. Stern, 1985, The Journal of clinical investigation.

The multiple levels of endothelial cell-coagulation factor interactions.

D. Stern, P. Nawroth, D. Handley, 1986, Clinics in haematology.

Observations on Coagulation Factors VII And X, and a Method for the Assay of Factor X in Blood Serum

D. Handley, K. Cheney, J. A. Bonnin, 1969, Pathology.

Surgery in a patient with an acquired circulating anticoagulant.

K. Taylor, D. Handley, H. Ellis, 1959, Lancet.

Erythropoietic uroporphyria of Gunther first presenting at 58 years with positive family studies.

D. Handley, A. Woodroffe, R. Pain, 1975, British medical journal.

Oxidation of ruthenium red for use as an intercellular tracer

S. Chien, D. Handley, 2004, Histochemistry.

1 – The Development and Application of Colloidal Gold as a Microscopic Probe

D. Handley, Dean A. Handley, 1989 .

Ultrastructural visualization of low-density lipoproteins during receptor binding and cellular endocytosis.

D. Handley, C. Arbeeny, D. Goodman, 1983, Journal of ultrastructure research.

A Circulating Anticoagulant Specific for Factor V

D. Handley, B. Duncan, 1969, Pathology.

Fibrinogen New York 1: The structural, functional, and genetic defects and an hypothesis of the role of fibrin in the regulation of coagulation and fibrinolysis

D. Handley, P. Wallén, C. Y. Liu, 1986 .

Platelet-activating factor in endotoxin and immune diseases

D. Handley, 1990 .

Stimulation of aortic smooth muscle cell mitogenesis by serotonin.

M. Moskowitz, S. Coughlin, D. Handley, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Effects of Oscillatory Mechanical Disturbance on Macromolecular Uptake by Arterial Wall

S. Weinbaum, S. Usami, C. Caro, 1981, Arteriosclerosis.

Pharmacodynamic Evaluation of the Neutralization of Endotoxin by PMX622 in Mice

P. Lake, D. Handley, F. Cerasoli, 2004, Antimicrobial Agents and Chemotherapy.

CAUSES OF THROMBOCYTOPENIA IN A HOSPITAL POPULATION: A SIX–MONTHS SURVEY OF 7,750 PATIENTS

D. Handley, R. Pembrey, E. Kimber, 1971, The Medical journal of Australia.

Preclinical pharmacology and possible mechanism of action of the novel antitumor agent 5-(4'-piperidinomethylphenyl)-2,3-dihydroimidazo [2,1-a]isoquinoline.

D. Handley, W. Houlihan, P. G. Munder, 1995, Arzneimittel-Forschung.

Effects of combined receptor antagonists of leukotriene D4 (LTD4) and platelet-activating factor (PAF) on rhesus airway responses to LTD4, PAF and antigen.

D. Handley, R. Patterson, R. Krell, 1989, International Archives of Allergy and Applied Immunology.

Fibers, crystals, and other forms of HbS polymers in deoxygenated sickle erythrocytes

D. Handley, S. Chien, Athanasia A. Kaperonis, 1986, American journal of hematology.

Gold labeling of thrombin and ultrastructural studies of thrombin-gold conjugate binding by fibrin.

D. Handley, S. Chien, C. Y. Liu, 1985, Analytical biochemistry.

Clinical Endoscopic Evaluation of the Gastroduodenal Tolerance to (R)‐ Ketoprofen, (R)‐ Flurbiprofen, Racemic Ketoprofen, and Paracetamol: A Randomized, Single‐Blind, Placebo‐Controlled Trial

J. McCray, D. Handley, T. P. Jerussi, 1998, Journal of clinical pharmacology.

The design and use of a simple device for rapid quench‐freezing of biological samples

D. Handley, J. T. Alexander, S. Chien, 1981, Journal of microscopy.

Lectin-Induced RBC Agglutination: Chemical vs. Cryofixation

D. Handley, L. Sung, S. Chien, 1980 .