N. von Ahsen

N. von Ahsen, M. Schön, A. Rosenberger, 2011, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Labeled primers for mutation scanning: making diagnostic use of the nucleobase quenching effect.

N. von Ahsen, 2003, Clinical chemistry.

Single-Nucleotide Polymorphism of CYP3A5 Impacts the Exposure to Tacrolimus in Pediatric Renal Transplant Recipients: A Pharmacogenetic Substudy of the TWIST Trial

B. Tönshoff, N. von Ahsen, M. Oellerich, 2017, Therapeutic drug monitoring.

Pre-analytical effects of different lithium heparin plasma separation tubes in the routine clinical chemistry laboratory

N. von Ahsen, M. Oellerich, J. Engelmayer, 2011, Clinical chemistry and laboratory medicine.

Cyclosporin A trough levels correlate with serum lipoproteins and apolipoproteins: implications for therapeutic drug monitoring of cyclosporin A.

V. Armstrong, N. von Ahsen, E. Schütz, 1997, Therapeutic drug monitoring.

No influence of the MDR-1 C3435T polymorphism or a CYP3A4 promoter polymorphism (CYP3A4-V allele) on dose-adjusted cyclosporin A trough concentrations or rejection incidence in stable renal transplant recipients.

V. Armstrong, M. Oellerich, N. von Ahsen, 2001, Clinical chemistry.

Improved Method for Therapeutic Drug Monitoring of 6-Thioguanine Nucleotides and 6-Methylmercaptopurine in Whole-Blood by LC/MSMS Using Isotope-Labeled Internal Standards

N. von Ahsen, M. Shipkova, H. Kirchherr, 2013, Therapeutic drug monitoring.

Serum S100β increases in marathon runners reflect extracranial release rather than glial damage

A. Fromme, M. Hasselblatt, W. Paulus, 2004, Neurology.

Use of two reporter dyes without interference in a single-tube rapid-cycle PCR: alpha(1)-antitrypsin genotyping by multiplex real-time fluorescence PCR with the LightCycler.

M. Oellerich, N. von Ahsen, E. Schütz, 2000, Clinical chemistry.

Genetic polymorphisms of cytochrome P450 among patients with Balkan endemic nephropathy (BEN).

D. Toncheva, V. Armstrong, N. von Ahsen, 2005, Clinical biochemistry.

SEVERE CARDIAC FAILURE IN A PATIENT WITH MULTIPLE SCLEROSIS FOLLOWING LOW-DOSE MITOXANTRONE TREATMENT

J. Dörr, F. Zipp, C. Lill, 2009, Neurology.

The HFE gene S65C polymorphism is rare among Bulgarian porphyria cutanea tarda patients.

M. Oellerich, N. von Ahsen, A. Ivanova, 2001, Journal of hepatology.

C282Y and H63D mutations in the HFE gene are not associated with porphyria cutanea tarda in bulgaria

M. Oellerich, N. von Ahsen, M. Oellerich, 1999, Hepatology.

6-thioguanine nucleotide-adapted azathioprine therapy does not lead to higher remission rates than standard therapy in chronic active crohn disease: results from a randomized, controlled, open trial.

V. Armstrong, H. Herfarth, G. Adler, 2007, Clinical chemistry.

Cryoglobulins interfere with platelet counts by optical and impedance methods but not with the CD61 immunoplatelet count.

M. Oellerich, N. von Ahsen, M. Oellerich, 2001, Clinical chemistry.

Macro-CK type 2 in metastatic prostate cancer

N. von Ahsen, S. Friedewald, L. Binder, 2018, Diagnosis.

Thrombophilia in patients with chronic venous leg ulcers‐a study on patients with or without post‐thrombotic syndrome

N. von Ahsen, M. Schön, A. Rosenberger, 2011, Journal of the European Academy of Dermatology and Venereology : JEADV.

Rapid Progression of Myelodysplastic Syndrome to Acute Myeloid Leukemia on Sequential Azathioprine, IFN-β and Copolymer-1 in a Patient with Multiple Sclerosis

D. Niederwieser, F. Then Bergh, N. von Ahsen, 2006, Acta Haematologica.

Increased Homocysteine Levels in Tear Fluid of Patients with Primary Open-Angle Glaucoma

J. Kornhuber, A. Jünemann, U. Schlötzer-Schrehardt, 2008, Ophthalmic Research.

Limitations of genotyping based on amplicon melting temperature.

M. Oellerich, N. von Ahsen, E. Schütz, 2001, Clinical chemistry.

Proteomics approach to identify the interacting partners of cellular prion protein and characterization of Rab7a interaction in neuronal cells.

W. Schulz-Schaeffer, I. Zerr, V. Armstrong, 2011, Journal of proteome research.

Analysis of two common alpha 1-antitrypsin deficiency alleles (PI*Z and PI*S) in subjects with periodontitis.

N. von Ahsen, R. Palmer, R. Wilson, 2002, Journal of clinical periodontology.

Role of the astrocytic ETB receptor in the regulation of extracellular endothelin‐1 during hypoxia

P. Lewczuk, H. Ehrenreich, M. Hasselblatt, 2001, Glia.

Low vitamin D and elevated immunoreactivity against Epstein–Barr virus before first clinical manifestation of multiple sclerosis

R. Gold, A. Chan, N. von Ahsen, 2012, Journal of Neurology, Neurosurgery & Psychiatry.

Analytic aspects of monitoring therapy with thiopurine medications.

V. Armstrong, N. von Ahsen, M. Oellerich, 2004, Therapeutic drug monitoring.

Therapie mit Thiopurin-Medikamenten TDM – und Pharmakogenomik der TPMT/Therapy with Thiopurine Drugs – TDM and Pharmacogenomics of TPMT

N. von Ahsen, Maria Shipkova, 2003 .

Longitudinal analyses of anti-JCV antibody index for risk assessment of progressive multifocal leukoencephalopathy

R. Gold, A. Chan, N. von Ahsen, 2016, Multiple sclerosis journal - experimental, translational and clinical.

Rapid, long-range molecular haplotyping of thiopurine S-methyltransferase (TPMT) *3A, *3B, and *3C.

V. Armstrong, N. von Ahsen, M. Oellerich, 2004, Clinical chemistry.

Kinetics and characteristics of an acute phase response following cardiac arrest

K. Eckardt, N. von Ahsen, C. Gleiter, 1999, Intensive Care Medicine.

Richtlinie: Labormedizinische Diagnostik bei der Therapie mit TPMT (Thiopurin-S-Methyltransferase)-abhängigen Pharmaka. Guidelines for the laboratory management of thiopurine drug therapy

K. Lackner, M. Schwab, N. von Ahsen, 2004 .

Rapid detection of ITPA 94C>A and IVS2 + 21A>C gene mutations by real-time fluorescence PCR and in vitro demonstration of effect of ITPA IVS2 + 21A>C polymorphism on splicing efficiency.

V. Armstrong, N. von Ahsen, M. Oellerich, 2004, Clinical chemistry.

Direct faecal PCR for diagnosis of Shiga-toxin-producing Escherichia coli.

N. von Ahsen, A. Gerritzen, D. Wolff, 2012, The Lancet. Infectious diseases.

FoxP3 demethylation is increased in human colorectal cancer and rat cholangiocarcinoma tissue.

D. Toncheva, P. Walson, N. von Ahsen, 2014, Clinical biochemistry.

Prediction of phenprocoumon maintenance dose and phenprocoumon plasma concentration by genetic and non-genetic parameters

E. Seifried, J. Oldenburg, N. von Ahsen, 2010, European Journal of Clinical Pharmacology.

Influencing factors of dsDNA dye (high-resolution) melting curves and improved genotype call based on thermodynamic considerations.

N. von Ahsen, E. Schütz, 2009, Analytical biochemistry.

Homocysteine levels in aqueous humor and plasma of patients with primary open-angle glaucoma

J. Kornhuber, A. Jünemann, U. Schlötzer-Schrehardt, 2006, Journal of Neural Transmission.

The intronic prothrombin 19911A>G polymorphism influences splicing efficiency and modulates effects of the 20210G>A polymorphism on mRNA amount and expression in a stable reporter gene assay system.

N. von Ahsen, M. Oellerich, 2004, Blood.

Two for typing: homogeneous combined single-nucleotide polymorphism scanning and genotyping.

N. von Ahsen, 2005, Clinical chemistry.

Spreadsheet software for thermodynamic melting point prediction of oligonucleotide hybridization with and without mismatches.

E Schütz, N von Ahsen, N. von Ahsen, 1999, BioTechniques.

Beta-Amlyoid 1–42 and Tau-Protein in Cerebrospinal Fluid of Patients with Parkinson’s Disease Dementia

J. Wiltfang, B. Mollenhauer, C. Trenkwalder, 2006, Dementia and Geriatric Cognitive Disorders.

A hematopoietic growth factor, thrombopoietin, has a proapoptotic role in the brain.

K. Nave, S. Sperling, H. Ehrenreich, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Pharmacogenetic screening for drug therapy: from single gene markers to decision making in the next generation sequencing era.

M. Tzvetkov, N. von Ahsen, 2012, Pathology.

ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis.

X. Montalban, F. Paul, J. Dörr, 2009, Brain : a journal of neurology.

DNA base bulge vs unmatched end formation in probe-based diagnostic insertion/deletion genotyping: genotyping the UGT1A1 (TA)(n) polymorphism by real-time fluorescence PCR.

M. Oellerich, N. von Ahsen, E. Schütz, 2000, Clinical chemistry.

Thrombopoietin inhibits nerve growth factor-induced neuronal differentiation and ERK signalling.

H. Ehrenreich, U. Rapp, K. Rajalingam, 2008, Cellular signalling.

Clinical Features of Rapidly Progressive Alzheimer’s Disease

H. Kretzschmar, B. Meissner, I. Zerr, 2010, Dementia and Geriatric Cognitive Disorders.

Measurement of erythrocyte inosine triphosphate pyrophosphohydrolase (ITPA) activity by HPLC and correlation of ITPA genotype-phenotype in a Caucasian population.

N. von Ahsen, M. Oellerich, M. Shipkova, 2006, Clinical chemistry.

Validation of a high-performance liquid chromatography method for thiopurine S-methyltransferase activity in whole blood using 6-mercaptopurine as substrate

M. Schwab, E. Schaeffeler, N. von Ahsen, 2017, Clinical chemistry and laboratory medicine.

Characterization of the Inosine Triphosphatase (ITPA) Gene: Haplotype Structure, Haplotype-Phenotype Correlation and Promoter Function

V. Armstrong, N. von Ahsen, M. Oellerich, 2008, Therapeutic drug monitoring.

Thiopurines Induce Oxidative Stress in T-Lymphocytes: A Proteomic Approach

N. von Ahsen, M. Oellerich, Misbah Misdaq, 2015, Mediators of inflammation.

A method for homogeneous color-compensated genotyping of factor V (G1691A) and methylenetetrahydrofolate reductase (C677T) mutations using real-time multiplex fluorescence PCR.

M. Oellerich, N. von Ahsen, E. Schütz, 2000, Clinical biochemistry.

Genotyping of eight thiopurine methyltransferase mutations: three-color multiplexing, "two-color/shared" anchor, and fluorescence-quenching hybridization probe assays based on thermodynamic nearest-neighbor probe design.

M. Oellerich, N. von Ahsen, E. Schütz, 2000, Clinical chemistry.

Identification of NQO1 and GSTs genotype frequencies in Bulgarian patients with Balkan endemic nephropathy.

D. Toncheva, V. Armstrong, N. von Ahsen, 2004, Journal of nephrology.

Prenatal dexamethasone exposure in the common marmoset monkey enhances gene expression of antioxidant enzymes in the aorta of adult offspring

M. Korecka, E. Fuchs, V. Armstrong, 2009, Stress.

Homocysteine and risk of open-angle glaucoma

J. Kornhuber, A. Jünemann, S. Bleich, 2002, Journal of Neural Transmission.

Analytical evaluation of a real-time PCR-based DNA demethylation assay to assess the frequency of naturally occurring regulatory T cells in peripheral blood.

N. von Ahsen, M. Shipkova, E. Wieland, 2016, Clinical biochemistry.

Extracellular Toxoplasma gondii tachyzoites do not require carbon source uptake for ATP maintenance, gliding motility and invasion in the first hour of their extracellular life.

N. von Ahsen, U. Groß, W. Bohne, 2011, International journal for parasitology.

Amyloid-β 1-42 levels are modified by apolipoprotein E ε4 in Creutzfeldt-Jakob disease in a similar manner as in Alzheimer's disease.

U. Heinemann, A. Krasnianski, D. Varges, 2011, Journal of Alzheimer's disease : JAD.

Rapid detection of prothrombotic mutations of prothrombin (G20210A), factor V (G1691A), and methylenetetrahydrofolate reductase (C677T) by real-time fluorescence PCR with the LightCycler.

V. Armstrong, N. von Ahsen, E. Schütz, 1999, Clinical chemistry.

cobas 8000 Modular Analyzer Series Evaluated under Routine-like Conditions at 14 Sites in Australia, Europe, and the United States

Graham Jones, Joachim Thiery, Roland Imdahl, 2013, Journal of laboratory automation.

Apolipoprotein E4 genotype is not associated with short-term cognition deficits during alcohol withdrawal.

J. Kornhuber, H. Frieling, S. Bleich, 2005, Alcohol.

In vitro Gender Differences in Neuronal Survival on Hypoxia and in 17β-Estradiol-Mediated Neuroprotection

H. Ehrenreich, M. Hasselblatt, N. von Ahsen, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Important role of nondiagnostic blood loss and blunted erythropoietic response in the anemia of medical intensive care patients*

K. Eckardt, N. von Ahsen, U. Frei, 1999, Critical care medicine.

Marmoset glutathione peroxidases: cDNA sequences, molecular evolution, and gene expression

V. Armstrong, N. von Ahsen, M. Oellerich, 2006, Journal of medical primatology.

CPAP-therapy effectively lowers serum homocysteine in obstructive sleep apnea syndrome

J. Kornhuber, S. Bleich, G. Mayer, 2004, Journal of Neural Transmission.

Impact of creatine kinase correction on the predictive value of S-100B after mild traumatic brain injury.

J. Bazarian, B. Blyth, M. Hasselblatt, 2006, Restorative neurology and neuroscience.

Apolipoprotein E gene polymorphism and previous alcohol withdrawal seizures.

J. Kornhuber, H. Frieling, S. Bleich, 2007, Journal of psychiatric research.

Application of a thermodynamic nearest-neighbor model to estimate nucleic acid stability and optimize probe design: prediction of melting points of multiple mutations of apolipoprotein B-3500 and factor V with a hybridization probe genotyping assay on the LightCycler.

E Schütz, N von Ahsen, V. Armstrong, 1999, Clinical chemistry.

Alzheimer’s Disease: Genetic Polymorphisms and Rate of Decline

I. Zerr, N. von Ahsen, M. Wolff, 2012, Dementia and Geriatric Cognitive Disorders.

Improved real-time multiplex polymerase chain reaction detection of methylenetetrahydrofolate reductase (MTHFR) 677C>T and 1298A>C polymorphisms using nearest neighbor model-based probe design.

Nicolas von Ahsen, N. von Ahsen, Raghunath P Agarwal, 2007, The Journal of molecular diagnostics : JMD.

Cognitive Impairment and Dementia in Elderly People Living in Rural Benin, West Africa

J. Dartigues, M. Guerchet, P. Preux, 2009, Dementia and Geriatric Cognitive Disorders.

Pseudohypercreatininemia due to Positive Interference in Enzymatic Creatinine Measurements Caused by Monoclonal IgM in Patients with Waldenström’s Macroglobulinemia

M. Oellerich, N. von Ahsen, G. Müller, 2000, Nephron.

C677T variant in the methylentetrahydrofolate reductase gene is a genetic risk factor for primary open-angle glaucoma.

J. Kornhuber, A. Jünemann, S. Bleich, 2005, American journal of ophthalmology-glaucoma.

Comparison and Harmonization of Different Semi-Automated and Automated qRT-PCR Assays in the Assessment of SARS-CoV-2

N. von Ahsen, M. Weig, W. Bohne, 2022, Viruses.

Differences in procalcitonin measurements between three BRAHMS-partnered immunoassays (Liaison, Elecsys and Architect)

N. von Ahsen, A. R. Asif, M. Schnelle, 2018, Clinical chemistry and laboratory medicine.

Multiple inducers and novel roles of autoantibodies against the obligatory NMDAR subunit NR1: a translational study from chronic life stress to brain injury

K. Nave, M. Hollmann, H. Ehrenreich, 2020, Molecular Psychiatry.

Rapid genotyping of human platelet antigen 5 with fluorophore‐labelled hybridization probes on the LightCycler

N. von Ahsen, E. Kretzschmar, H. Trobisch, 2001, British journal of haematology.

Chip-based genotyping: translation of pharmacogenetic research to clinical practice.

N. von Ahsen, M. Oellerich, 2007, Clinical chemistry.

Lack of correlation between Treg quantification assays in inflammatory bowel disease patients.

P. Walson, N. von Ahsen, M. Oellerich, 2015, World journal of gastroenterology.

ATP-binding cassette transporters in inflammatory brain disease.

R. Gold, A. Chan, N. von Ahsen, 2011, Current pharmaceutical design.

CYP2D6 and CYP2C19 in Papua New Guinea: High frequency of previously uncharacterized CYP2D6 alleles and heterozygote excess.

J. Brockmöller, M. Tzvetkov, I. Mueller, 2010, International journal of molecular epidemiology and genetics.