R. Snyder

发表

Pharmacokinetics of dibutylphthalate in pregnant rats.

W. Krol, T. Fennell, S. Sumner, 2004, Toxicological sciences : an official journal of the Society of Toxicology.

Simulated Gastric Digestion and In Vivo Intestinal Uptake of Orally Administered CuO Nanoparticles and TiO2 E171 in Male and Female Rat Pups

S. Aravamudhan, T. Fennell, S. Sumner, 2021, Nanomaterials.

Does the mass spectrometer define the marker? A comparison of global metabolite profiling data generated simultaneously via UPLC-MS on two different mass spectrometers.

I. Wilson, G. Theodoridis, H. Gika, 2010, Analytical chemistry.

Role of CYP2E1 in the epoxidation of acrylamide to glycidamide and formation of DNA and hemoglobin adducts.

Rodney Snyder, M. Churchwell, T. Fennell, 2005, Toxicological sciences : an official journal of the Society of Toxicology.

Effects of Phendimetrazine Treatment on Cocaine vs Food Choice and Extended-Access Cocaine Consumption in Rhesus Monkeys

T. Fennell, R. Snyder, B. Blough, 2013, Neuropsychopharmacology.

Identifying structural determinants of potency for analogs of apelin-13: integration of C-terminal truncation with structure-activity.

R. Snyder, S. Runyon, Yanyan Zhang, 2014, Bioorganic & medicinal chemistry.

Distribution and biomarker of carbon‐14 labeled fullerene C60 ([14C(U)]C60) in pregnant and lactating rats and their offspring after maternal intravenous exposure

N. Holland, T. Fennell, S. Sumner, 2015, Journal of applied toxicology : JAT.

Identification of neuropeptide S antagonists: structure-activity relationship studies, X-ray crystallography, and in vivo evaluation.

J. Deschamps, T. Fennell, R. Snyder, 2014, ACS chemical neuroscience.

Metabolism and disposition of bisphenol A in female rats.

T. Fennell, R. Snyder, K. Gaido, 2000, Toxicology and applied pharmacology.

Disposition and metabolism of antibacterial agent, triclocarban, in rodents; a species and route comparison

T. Fennell, R. Snyder, J. Stanko, 2020, Xenobiotica; the fate of foreign compounds in biological systems.

Disposition of tris(4-chlorophenyl)methanol and tris(4-chlorophenyl)methane in male and female Harlan Sprague Dawley rats and B6C3F1/N mice following oral and intravenous administration

T. Fennell, R. Snyder, S. Watson, 2019, Xenobiotica; the fate of foreign compounds in biological systems.

Towards rational design of cannabinoid receptor 1 (CB1) antagonists for peripheral selectivity.

K. Bortoff, R. Snyder, R. Maitra, 2011, Bioorganic & medicinal chemistry letters.

Design and synthesis of cannabinoid receptor 1 antagonists for peripheral selectivity.

K. Bortoff, T. Fennell, R. Snyder, 2012, Journal of medicinal chemistry.

Kinetic and metabolic profiles of synthetic cannabinoids NNEI and MN-18.

I. McGregor, T. Fennell, R. Snyder, 2018, Drug testing and analysis.

In vitro and in vivo pharmacokinetics and metabolism of synthetic cannabinoids CUMYL-PICA and 5F-CUMYL-PICA

I. McGregor, T. Fennell, R. Snyder, 2017, Forensic Toxicology.

Erratum to: In vitro and in vivo pharmacokinetics and metabolism of synthetic cannabinoids CUMYL-PICA and 5F-CUMYL-PICA

I. McGregor, T. Fennell, R. Snyder, 2017, Forensic Toxicology.

Blocking Alcoholic Steatosis in Mice with a Peripherally Restricted Purine Antagonist of the Type 1 Cannabinoid Receptor.

R. Snyder, S. Runyon, R. Wiethe, 2018, Journal of medicinal chemistry.

Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3 R)-7-Hydroxy- N-[(1 S)-2-methyl-1-(piperidin-1-ylmethyl)propyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (PDTic).

T. Fennell, R. Snyder, James B. Thomas, 2018, Journal of medicinal chemistry.

Intravenous administration of three multiwalled carbon nanotubes to female rats and their effect on urinary biochemical profile

T. Fennell, S. Sumner, R. Snyder, 2021, Journal of applied toxicology : JAT.

Reaction of the butter flavorant diacetyl (2,3-butanedione) with N-α-acetylarginine: a model for epitope formation with pulmonary proteins in the etiology of obliterative bronchiolitis.

D. Morgan, R. Snyder, S. Watson, 2010, Journal of agricultural and food chemistry.

Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3 R)- N-[1 R)-1-(Cyclohexylmethyl)-2-methylpropyl]-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (CDTic).

T. Fennell, R. Snyder, James B. Thomas, 2018, Journal of medicinal chemistry.

Peripherally selective diphenyl purine antagonist of the CB1 receptor.

K. Bortoff, T. Fennell, R. Snyder, 2013, Journal of medicinal chemistry.

Sex Differences in the Effects of a Kappa Opioid Receptor Antagonist in the Forced Swim Test

B. Trainor, J. Silverman, T. Fennell, 2018, Front. Pharmacol..

Pharmacodynamic Relationships between Duration of Action of JDTic-like Kappa-Opioid Receptor Antagonists and Their Brain and Plasma Pharmacokinetics in Rats.

S. M. Owens, J. L. Howard, T. Fennell, 2016, ACS chemical neuroscience.

Pyrazole antagonists of the CB1 receptor with reduced brain penetration.

K. Bortoff, R. Snyder, R. Wiethe, 2016, Bioorganic & medicinal chemistry.

Diphenyl purine derivatives as peripherally selective cannabinoid receptor 1 antagonists.

K. Bortoff, T. Fennell, R. Snyder, 2012, Journal of medicinal chemistry.

Metabolomics of brain and reproductive organs: characterizing the impact of gestational exposure to butylbenzyl phthalate on dams and resultant offspring

R. Snyder, W. Pathmasiri, S. McRitchie, 2012, Metabolomics.

Isoquinolone derivatives as lysophosphatidic acid receptor 5 (LPA5) antagonists: Investigation of structure-activity relationships, ADME properties and analgesic effects.

Y. Tao, R. Snyder, P. Patel, 2022, European journal of medicinal chemistry.

Neuropeptide B/W receptor 1 peptidomimetic agonists: Structure-activity relationships and plasma stability.

R. Snyder, T. Gamage, A. Decker, 2022, European journal of medicinal chemistry.

Peripherally Selective Cannabinoid 1 Receptor (CB1R) Agonists for the Treatment of Neuropathic Pain.

I. Spigelman, R. Snyder, B. Thomas, 2016, Journal of medicinal chemistry.

Metabolism and disposition of 2-ethylhexyl-p-methoxycinnamate following oral gavage and dermal exposure in Harlan Sprague Dawley rats and B6C3F1/N mice and in hepatocytes in vitro

T. Fennell, R. Snyder, B. McIntyre, 2018, Xenobiotica; the fate of foreign compounds in biological systems.

Metabolism and hemoglobin adduct formation of acrylamide in humans.

T. Fennell, S. Sumner, R. Snyder, 2005, Toxicological sciences : an official journal of the Society of Toxicology.

Evaluating In Vitro-In Vivo Extrapolation of Toxicokinetics

Robert G. Pearce, Barbara A Wetmore, Nisha S Sipes, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

Bisphenol F has different effects on preadipocytes differentiation and weight gain in adult mice as compared with Bisphenol A and S.

T. Fennell, R. Snyder, E. Rissman, 2019, Toxicology.

Metabolism and disposition of 2-methoxy-4-nitroaniline in male and female Harlan Sprague Dawley rats and B6C3F1/N mice

T. Fennell, R. Snyder, P. Patel, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

Disposition and metabolism of N-butylbenzenesulfonamide in Sprague Dawley rats and B6C3F1/N mice and in vitro in hepatocytes from rats, mice, and humans.

C. Rider, T. Fennell, R. Snyder, 2019, Toxicology letters.

Biomarkers for the Assessment of Acetaminophen Induced Liver Injury

T. Fennell, S. Sumner, R. Snyder, 2011 .

Attenuation of cocaine self-administration by chronic oral phendimetrazine in rhesus monkeys

M. Nader, T. Fennell, R. Snyder, 2016, Neuroscience.

Role of phenmetrazine as an active metabolite of phendimetrazine: evidence from studies of drug discrimination and pharmacokinetics in rhesus monkeys.

T. Fennell, R. Snyder, B. Blough, 2013, Drug and alcohol dependence.

Role of d-amphetamine and d-methamphetamine as active metabolites of benzphetamine: Evidence from drug discrimination and pharmacokinetic studies in male rhesus monkeys

T. Fennell, R. Snyder, M. Banks, 2017, Pharmacology Biochemistry and Behavior.

Route of administration effects on nicotine discrimination in female and male mice.

R. Snyder, B. Thomas, J. Wiley, 2019, Drug and alcohol dependence.

Dosimetry of Acrylamide and Glycidamide Over the Lifespan in a 2-Year Bioassay of Acrylamide in Wistar Han Rats

T. Fennell, R. Snyder, M. Friedman, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

Kinetics of elimination of urinary metabolites of acrylamide in humans.

T. Fennell, S. Sumner, R. Snyder, 2006, Toxicological sciences : an official journal of the Society of Toxicology.

Acrylamide: a comparison of metabolism and hemoglobin adducts in rodents following dermal, intraperitoneal, oral, or inhalation exposure.

Bahman Asgharian, W. Krol, T. Fennell, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Oral administration of TiO2 nanoparticles during early life impacts cardiac and neurobehavioral performance and metabolite profile in an age- and sex-related manner

S. Aravamudhan, T. Fennell, S. Sumner, 2022, Particle and Fibre Toxicology.

Biodistribution, cardiac and neurobehavioral assessments, and neurotransmitter quantification in juvenile rats following oral administration of aluminum oxide nanoparticles

S. Aravamudhan, T. Fennell, S. Sumner, 2020, Journal of applied toxicology : JAT.

Disposition of [14C]hydroquinone in Harlan Sprague-Dawley rats and B6C3F1/N mice: species and route comparison

T. Fennell, R. Snyder, S. Watson, 2018, Xenobiotica; the fate of foreign compounds in biological systems.

Disposition and metabolism of sulfolane in Harlan Sprague Dawley rats and B6C3F1/N mice and in vitro in hepatocytes from rats, mice, and humans

C. Blystone, T. Fennell, R. Snyder, 2019, Xenobiotica; the fate of foreign compounds in biological systems.

Investigation of the low-dose response in the in vivo induction of micronuclei and adducts by acrylamide.

Leslie Recio, Errol Zeiger, Joseph K Haseman, 2009, Toxicological sciences : an official journal of the Society of Toxicology.

Functionalized 6-(Piperidin-1-yl)-8,9-Diphenyl Purines as Peripherally Restricted Inverse Agonists of the CB1 Receptor.

R. Snyder, S. Runyon, R. Wiethe, 2019, Journal of medicinal chemistry.

Identification of a Novel Neuropeptide S Receptor Antagonist Scaffold Based on the SHA-68 Core

R. Snyder, S. Runyon, R. Uprety, 2021, Pharmaceuticals.

Comparison of the hemoglobin adducts formed by administration of N-methylolacrylamide and acrylamide to rats.

W. Krol, T. Fennell, S. Sumner, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Distribution of carbon‐14 labeled C60 ([14C]C60) in the pregnant and in the lactating dam and the effect of C60 exposure on the biochemical profile of urine

T. Fennell, R. Snyder, A. Lewin, 2010, Journal of applied toxicology : JAT.

Relation between dietary acrylamide exposure and biomarkers of internal dose in Canadian teenagers

T. Fennell, R. Snyder, É. Gaudreau, 2014, Journal of Exposure Science and Environmental Epidemiology.

Metabolism and disposition of [14C]n-butyl-p-hydroxybenzoate in male and female Harlan Sprague Dawley rats following oral administration and dermal application

C. Blystone, T. Fennell, R. Snyder, 2013, Xenobiotica; the fate of foreign compounds in biological systems.

Development of an Analytical Method for Assessment of Silver Nanoparticle Content in Biological Matrices by Inductively Coupled Plasma Mass Spectrometry

M. A. Levine, J. Harrington, T. Fennell, 2015, Biological Trace Element Research.

Metabolomics in the assessment of chemical‐induced reproductive and developmental outcomes using non‐invasive biological fluids: application to the study of butylbenzyl phthalate

R. Tyl, T. Fennell, S. Sumner, 2009, Journal of applied toxicology : JAT.

Disposition and metabolism of the bisphenol analogue, bisphenol S, in Harlan Sprague Dawley rats and B6C3F1/N mice and in vitro in hepatocytes from rats, mice, and humans

T. Fennell, R. Snyder, S. Watson, 2018, Toxicology and applied pharmacology.

Disposition of intravenously or orally administered silver nanoparticles in pregnant rats and the effect on the biochemical profile in urine

J. Harrington, T. Fennell, R. Snyder, 2017, Journal of applied toxicology : JAT.

Distribution and biomarkers of carbon‐14‐labeled fullerene C60 ([14C(U)]C60) in female rats and mice for up to 30 days after intravenous exposure

N. Holland, T. Fennell, R. Snyder, 2015, Journal of applied toxicology : JAT.

Metabolomics of urine for the assessment of microvesicular lipid accumulation in the liver following isoniazid exposure

T. Fennell, S. Sumner, R. Snyder, 2010, Metabolomics.

Direct and transgenerational effects of low doses of perinatal di-(2-ethylhexyl) phthalate (DEHP) on social behaviors in mice

R. Snyder, S. Sumner, E. Rissman, 2017, PloS one.

Placental trophoblast transfer of opioids following exposures to individual or mixtures of opioids in vitro

T. Fennell, R. Snyder, N. Mortensen, 2019, Experimental biology and medicine.

Metabolomics of urine and liver for the assessment of acetaminophen induced liver injury

T. Fennell, S. Sumner, R. Snyder, 2010 .

Disposition of bisphenol AF, a bisphenol A analogue, in hepatocytes in vitro and in male and female Harlan Sprague-Dawley rats and B6C3F1/N mice following oral and intravenous administration

T. Fennell, R. Snyder, P. Patel, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

The effect of ethylene exposure on ethylene oxide in blood and on hepatic cytochrome p450 in Fischer rats.

T. Fennell, R. Snyder, C. Parkinson, 2004, Toxicological sciences : an official journal of the Society of Toxicology.

Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as inverse agonists of the CB1 receptor - SAR efforts towards selectivity and peripheralization.

R. Snyder, S. Runyon, R. Wiethe, 2019, Bioorganic & medicinal chemistry.

Synthesis and pharmacological characterization of functionalized 6-piperazin-1-yl-purines as cannabinoid receptor 1 (CB1) inverse agonists.

R. Snyder, S. Runyon, R. Wiethe, 2018, Bioorganic & medicinal chemistry.