B. Abbott

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The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat.

L. Gray, J. Ostby, L. Parks, 2000, Toxicological sciences : an official journal of the Society of Toxicology.

Placental defects in ARNT‐knockout conceptus correlate with localized decreases in VEGF‐R2, Ang‐1, and Tie‐2

B. Abbott, A. Buckalew, 2000, Developmental dynamics : an official publication of the American Association of Anatomists.

Etiology of retinoic acid-induced cleft palate varies with the embryonic stage.

L. Birnbaum, M. Harris, B. Abbott, 1989, Teratology.

Characterizing cleft palate toxicants using ToxCast data, chemical structure, and the biomedical literature.

Nancy C. Baker, Jill A. Franzosa, Nisha S. Sipes, 2019, Birth defects research.

AhR, ARNT, and CYP1A1 mRNA quantitation in cultured human embryonic palates exposed to TCDD and comparison with mouse palate in vivo and in culture.

G. Held, B. Abbott, J. Schmid, 1999, Toxicological sciences : an official journal of the Society of Toxicology.

TCDD-induced altered expression of growth factors may have a role in producing cleft palate and enhancing the incidence of clefts after coadministration of retinoic acid and TCDD.

L. Birnbaum, B. Abbott, 1990, Toxicology and applied pharmacology.

Developmental expression of two members of a new class of transcription factors: II. Expression of aryl hydrocarbon receptor nuclear translocator in the C57BL/6N mouse embryo

B. Abbott, M. Probst, 1995, Developmental dynamics : an official publication of the American Association of Anatomists.

Gene Profiling in the Livers of Wild-type and PPARα-Null Mice Exposed to Perfluorooctanoic Acid

J. Corton, M. Rosen, C. Lau, 2008, Toxicologic pathology.

Embryonic Midfacial Palatal Organ Culture Methods in Developmental Toxicology.

B. Abbott, 2019, Methods in molecular biology.

EGF and TGF-α Expression Influence the Developmental Toxicity of TCDD: Dose Response and AhR Phenotype in EGF, TGF-α, and EGF + TGF-α Knockout Mice

P. L. Bryant, M. DeVito, B. Abbott, 2003 .

Effects of TCDD on embryonic ureteric epithelial EGF receptor expression and cell proliferation.

L. Birnbaum, B. Abbott, B. Abbott, 1990, Teratology.

Methoxychlor-Induced Alterations in the Histological Expression of Angiogenic Factors in Pituitary and Uterus

B. Abbott, J. Goldman, A. Murr, 2003, Journal of Molecular Histology.

Comparative Hepatic Effects of Perfluorooctanoic Acid and WY 14,643 in PPAR-α Knockout and Wild-type Mice

M. Rosen, C. Lau, D. Wolf, 2008, Toxicologic pathology.

Activation of mouse and human peroxisome proliferator-activated receptor alpha by perfluoroalkyl acids of different functional groups and chain lengths.

C. Lau, B. Abbott, C. Wolf, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Developmental toxicity of perfluorooctane sulfonate (PFOS) is not dependent on expression of peroxisome proliferator activated receptor-alpha (PPAR alpha) in the mouse.

C. Lau, B. Abbott, C. Wolf, 2009, Reproductive toxicology.

Developmental Effects of Perfluorononanoic Acid in the Mouse Are Dependent on Peroxisome Proliferator-Activated Receptor-Alpha

C. Lau, B. Abbott, C. Wolf, 2010, PPAR research.

Activation of mouse and human peroxisome proliferator-activated receptor-alpha (PPARα) by perfluoroalkyl acids (PFAAs): further investigation of C4-C12 compounds.

C. Lau, B. Abbott, C. Wolf, 2012, Reproductive toxicology.

Testing for departures from additivity in mixtures of perfluoroalkyl acids (PFAAs).

C. Gennings, C. Lau, B. Abbott, 2013, Toxicology.

Effects of perfluorooctanoic acid (PFOA) on expression of peroxisome proliferator-activated receptors (PPAR) and nuclear receptor-regulated genes in fetal and postnatal CD-1 mouse tissues.

C. Lau, C. Wood, K. Tatum-Gibbs, 2012, Reproductive toxicology.

Peroxisome Proliferator-Activated Receptors Alpha, Beta, and Gamma mRNA and Protein Expression in Human Fetal Tissues

C. Lau, C. Wood, B. Abbott, 2010, PPAR research.

Adrenocorticotropin (ACTH) and corticosterone secretion by perifused pituitary and adrenal glands from rodents exposed to 2,3,7, 8-tetrachlorodibenzo-p-dioxin (TCDD).

D. House, B. Abbott, A. Buckalew, 2000, Toxicology.

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) disrupts early morphogenetic events that form the lower reproductive tract in female rat fetuses.

L. Birnbaum, B. Abbott, J. Schmid, 2002, Toxicological sciences : an official journal of the Society of Toxicology.

Perfluoroalkyl acids-induced liver steatosis: Effects on genes controlling lipid homeostasis.

J. Corton, C. Lau, C. Wood, 2017, Toxicology.

Engineering epithelial-stromal interactions in vitro for toxicology assessment.

B. Abbott, David G. Belair, 2017, Toxicology.

Screening for developmental toxicity of tobacco smoke constituents.

J. M. Rogers, B. Abbott, J. Rogers, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Immunohistochemical double-staining for Ah receptor and ARNT in human embryonic palatal shelves.

G. Perdew, B. Abbott, M. Probst, 1994, Teratology.

Adverse reproductive outcomes in the transgenic Ah receptor-deficient mouse.

G. Held, B. Abbott, J. Schmid, 1999, Toxicology and applied pharmacology.

Review of the interaction between TCDD and glucocorticoids in embryonic palate.

B. Abbott, 1995, Toxicology.

2,3,7,8-Tetrachlorodibenzo-p-dioxin alters embryonic palatal medial epithelial cell differentiation in vitro.

L. Birnbaum, B. Abbott, J. Diliberto, 1989, Toxicology and applied pharmacology.

TCDD exposure of human embryonic palatal shelves in organ culture alters the differentiation of medial epithelial cells.

L. Birnbaum, B. Abbott, 1991, Teratology.

TCDD alters the extracellular matrix and basal lamina of the fetal mouse kidney.

L. Birnbaum, B. Abbott, R. Pratt, 1987, Teratology.

TCDD-induced hyperplasia of the ureteral epithelium produces hydronephrosis in murine fetuses.

L. Birnbaum, B. Abbott, R. Pratt, 1987, Teratology.

Effects of TCDD on Ah receptor, ARNT, EGF, and TGF-α expression in embryonic mouse urinary tract

P. L. Bryant, G. Clark, B. Abbott, 1997 .

Glucocorticoid receptor regulation in the rat embryo: a potential site for developmental toxicity?

G. Held, C. Lau, C. Wood, 2000, Toxicology and applied pharmacology.

Mechanisms of TCDD-induction of cleft palate: insights from invivo and invitro approaches

L. Birnbaum, B. Abbott, J. Diliberto, 1992 .

Induction of ethoxyresorufin-O-deethylase and inhibition of glucocorticoid receptor binding in skin and liver of haired and hairless HRS/J mice by topically applied 2,3,7,8-tetrachlorodibenzo-p-dioxin.

F. Lin, L. Birnbaum, B. Abbott, 1990, Toxicology.

PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling.

J. Corton, M. Rosen, C. Lau, 2017, Toxicology.

The effects of perfluorinated chemicals on adipocyte differentiation in vitro

C. Wood, B. Abbott, Andrew M. Watkins, 2015, Molecular and Cellular Endocrinology.

2 , 3 , 7 , 8-Tetrachlorodibenzo-p-dioxin in Pregnant Long Evans Rats : Disposition to Maternal and Embryo / Fetal Tissues 1

M. DeVito, B. Abbott, C. H. Hurst, 2005 .

2,3,7,8-Tetrachlorodibenzo-p-dioxin in pregnant Long Evans rats: disposition to maternal and embryo/fetal tissues.

M. DeVito, L. Birnbaum, B. Abbott, 1998, Toxicological sciences : an official journal of the Society of Toxicology.

Rapid distribution of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) to embryonic tissues in C57BL/6N mice and correlation with palatal uptake in vitro.

L. Birnbaum, B. Abbott, J. Diliberto, 1996, Toxicology and applied pharmacology.

PPARs and Xenobiotic-Induced Adverse Effects: Relevance to Human Health

J. Corton, C. Lau, B. Abbott, 2011, PPAR research.

Evaluation of perfluoroalkyl acid activity using primary mouse and human hepatocytes.

M. Rosen, C. Lau, C. Wood, 2013, Toxicology.

Effects of perfluorooctanoic acid on mouse mammary gland development and differentiation resulting from cross-foster and restricted gestational exposures.

A. Calafat, S. Fenton, B. Abbott, 2009, Reproductive toxicology.

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on fetal mouse urinary tract epithelium in vitro.

P. L. Bryant, B. Abbott, L. Reid, 2001, Toxicology.

Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium

J. Corton, M. Rosen, Russell S. Thomas, 2015, PloS one.

A Three-Dimensional Organoid Culture Model to Assess the Influence of Chemicals on Morphogenetic Fusion

C. Wood, B. Abbott, C. Wolf, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

Development of an organotypic stem cell model for the study of human embryonic palatal fusion.

B. Abbott, C. Wolf, David G. Belair, 2018, Birth defects research.

Engineering human cell spheroids to model embryonic tissue fusion in vitro

Hongzu Ren, C. Wood, A. Swank, 2017, PloS one.

AH receptor, ARNT, glucocorticoid receptor, EGF receptor, EGF, TGF alpha, TGF beta 1, TGF beta 2, and TGF beta 3 expression in human embryonic palate, and effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

G. Perdew, B. Abbott, A. Buckalew, 1998, Teratology.

Activation of mouse and human peroxisome proliferator-activated receptors (alpha, beta/delta, gamma) by perfluorooctanoic acid and perfluorooctane sulfonate.

B. Abbott, Margy L. Takacs, 2007, Toxicological sciences : an official journal of the Society of Toxicology.

Elevated Plasma Transforming Growth Factor-β1 Levels in Breast Cancer Patients Decrease After Surgical Removal of the Tumor

M. Anscher, R. Jirtle, J. Iglehart, 1995, Annals of surgery.

Retinoic acid-induced alterations in the expression of growth factors in embryonic mouse palatal shelves.

L. Birnbaum, B. Abbott, 1990, Teratology.

Interactive regulation of Ah and glucocorticoid receptors in the synergistic induction of cleft palate by 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone.

L. Birnbaum, G. Perdew, B. Abbott, 1994, Toxicology and applied pharmacology.

Early events following maternal exposure to 5-fluorouracil lead to dysmorphology in cultured embryonic tissues.

J. M. Rogers, B. Abbott, A. Buckalew, 1994, Teratology.

Retinoic acid inhibits migration of cranial neural crest cells in the cultured mouse embryo.

B. Abbott, E. Goulding, R. Pratt, 1987, Journal of craniofacial genetics and developmental biology.

Toxicogenomic Dissection of the Perﬂuorooctanoic Acid Transcript Proﬁle in Mouse Liver: Evidence for the Involvement of Nuclear Receptors PPAR a and CAR

J. Corton, Hongzu Ren, M. Rosen, 2008 .

Approaches for evaluation of mode of action

M. Rosen, C. Wood, B. Abbott, 2016 .

Effects of methanol on embryonic mouse palate in serum-free organ culture.

B. Abbott, T R Logsdon, T S Wilke, 1994, Teratology.

Organ Culture of Midfacial Tissue and Secondary Palate

B. Abbott, 2003, Current protocols in toxicology.

Embryonic palatal responses to teratogens in serum-free organ culture.

B. Abbott, A. Buckalew, 1992, Teratology.

The etiology of cleft palate: a 50-year search for mechanistic and molecular understanding.

B. Abbott, 2010, Birth defects research. Part B, Developmental and reproductive toxicology.

Retinoic acid alters EGF receptor expression during palatogenesis.

E. Adamson, B. Abbott, R. Pratt, 1988, Development.

Effects of 5-fluorouracil on embryonic rat palate in vitro: fusion in the absence of proliferation.

W. Setzer, R. Kavlock, C. Lau, 1993, Teratology.

Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo

L. Birnbaum, G. Perdew, B. Abbott, 1995, Developmental dynamics : an official publication of the American Association of Anatomists.

Cellular, Biochemical, and Molecular Techniques in Developmental Toxicology

M. Rosen, G. Held, B. Abbott, 2005 .

Gene Expression Profiling in Wild-Type and PPARα-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPARα-Independent Effects

J. Corton, M. Rosen, C. Lau, 2010, PPAR research.

Review of the expression of peroxisome proliferator-activated receptors alpha (PPAR alpha), beta (PPAR beta), and gamma (PPAR gamma) in rodent and human development.

B. Abbott, 2009, Reproductive toxicology.

Processes involved in retinoic acid production of small embryonic palatal shelves and limb defects.

L. Birnbaum, B. Abbott, L. Hill, 1990, Teratology.

Comparisons of the effects of TCDD and hydrocortisone on growth factor expression provide insight into their interaction in the embryonic mouse palate.

L. Birnbaum, M. Harris, B. Abbott, 1992, Teratology.

Developmental toxicity of dioxin : Searching for the cellular and molecular basis of morphological responses

B. Abbott, 1997 .

Rat embryonic palatal shelves respond to TCDD in organ culture.

L. Birnbaum, B. Abbott, 1990, Toxicology and applied pharmacology.

Disruption of antennal morphogenesis in Bracon hebetor by exposure to triethylamine

B. Abbott, 1987 .

Perfluorooctanoic acid induced developmental toxicity in the mouse is dependent on expression of peroxisome proliferator activated receptor-alpha.

C. Lau, S. Nakayama, B. Abbott, 2007, Toxicological sciences : an official journal of the Society of Toxicology.

Cell death in rat and mouse embryos exposed to methanol in whole embryo culture.

M. Ebron-McCoy, B. Abbott, J. Andrews, 1995, Toxicology.

Transcriptional ontogeny of the developing liver

J. Corton, Beena Vallanat, B. Abbott, 2012, BMC Genomics.

A systematic evaluation of the potential effects of trichloroethylene exposure on cardiac development

Christina M. Powers, T. Knudsen, S. Makris, 2016, Reproductive toxicology.

AH receptor, ARNT, glucocorticoid receptor, EGF receptor, EGF, TGFα, TGFβ1, TGFβ2, and TGFβ3 expression in human embryonic palate, and effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)†

G. Perdew, B. Abbott, A. Buckalew, 1998 .

Teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the expression of EGF and/or TGF-alpha.

P. L. Bryant, S. Fenton, B. Abbott, 2001, Toxicological sciences : an official journal of the Society of Toxicology.

Epithelial-Stromal Interaction FGF Fibroblast Growth Factor FPC Fetal Pulmonary Cell HDF Human Dermal Fibroblast HESC Human Embryonic Stem Cell HEK Human Epidermal Keratinocyte HGF Hepatocyte Growth Factor HIPSC Human Induced Pluripotent Stem Cell HMVEC Human Microvascular Endothelial Cell HWJSC Hum

B. Abbott, 2017 .

Effects of epidermal growth factor (EGF), transforming growth factor-α (TGFα), and 2,3,7,8- tetrachlorodibenzo-p-dioxin on fusion of embryonic palates in serum-free organ culture using wild-type, EGF knockout, and TGFα knockout mouse strains

B. Abbott, A. Buckalew, Korin E. Leffler, 2005 .

Teratogenic effects of retinoic acid are modulated in mice lacking expression of epidermal growth factor and transforming growth factor-alpha.

B. Abbott, M. G. Narotsky, D. Best, 2005, Birth defects research. Part A, Clinical and molecular teratology.

TCDD alters medial epithelial cell differentiation during palatogenesis.

L. Birnbaum, B. Abbott, 1989, Toxicology and applied pharmacology.

Cellular alterations and enhanced induction of cleft palate after coadministration of retinoic acid and TCDD.

L. Birnbaum, B. Abbott, 1989, Toxicology and applied pharmacology.

EGF receptor expression in the developing tooth is altered by exogenous retinoic acid and EGF.

B. Abbott, R. Pratt, 1988, Developmental biology.

An in vitro model for murine ureteric epithelial cells

P. L. Bryant, B. Abbott, L. Reid, 2001, In Vitro Cellular & Developmental Biology - Animal.

Activation of Mouse and Human Peroxisome Proliferator-Activated Receptors ( , / , ) by Perfluorooctanoic Acid and Perfluorooctane Sulfonate

B. Abbott, Margy L. Takacs, Barbara D. Abbott, 2006 .

Developmental toxicity of perfluorooctanoic acid in the CD-1 mouse after cross-foster and restricted gestational exposures.

A. Calafat, C. Lau, S. Fenton, 2006, Toxicological sciences : an official journal of the Society of Toxicology.

Evaluating the additivity of perfluoroalkyl acids in binary combinations on peroxisome proliferator-activated receptor-α activation.

C. Lau, C. Rider, B. Abbott, 2014, Toxicology.

RT-PCR quantification of AHR, ARNT, GR, and CYP1A1 mRNA in craniofacial tissues of embryonic mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone.

G. Held, B. Abbott, J. Schmid, 1999, Toxicological sciences : an official journal of the Society of Toxicology.

Expression of AhR and ARNT mRNA in cultured human endometrial explants exposed to TCDD.

S. Koury, B. Abbott, R. Batt, 2001, Toxicological sciences : an official journal of the Society of Toxicology.

Retinoic acid alters epithelial differentiation during palatogenesis.

B. Abbott, R. Pratt, 1991, Journal of craniofacial genetics and developmental biology.

Transcriptional ontogeny of the developing liver

J. Corton, Beena Vallanat, B. Abbott, 2012, BMC Genomics.

EGF and TGF-alpha expression influence the developmental toxicity of TCDD: dose response and AhR phenotype in EGF, TGF-alpha, and EGF + TGF-alpha knockout mice.

P. L. Bryant, M. DeVito, B. Abbott, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances toward understanding the mechanism.

L S Birnbaum, L. Birnbaum, B. Abbott, 1990, Teratology.

Toxicogenomic dissection of the perfluorooctanoic acid transcript profile in mouse liver: evidence for the involvement of nuclear receptors PPAR alpha and CAR.

J Christopher Corton, Beena Vallanat, J. Corton, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Influence of retinoids and EGF on growth of embryonic mouse palatal epithelia in culture

B. Abbott, R. Pratt, 1988, In Vitro Cellular & Developmental Biology.

Teratogenicity of benzoic acid derivatives of retinoic acid in cultured mouse embryos.

B. Abbott, A. Jetten, E. Goulding, 1988, Reproductive toxicology.

Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice.

J. Peters, F. Gonzalez, P. Fernández-Salguero, 1999, Toxicological sciences : an official journal of the Society of Toxicology.

Ah receptor in embryonic mouse palate and effects of TCDD on receptor expression.

L. Birnbaum, G. Perdew, B. Abbott, 1994, Toxicology and applied pharmacology.

Effects of epidermal growth factor (EGF), transforming growth factor-alpha (TGFalpha), and 2,3,7,8-tetrachlorodibenzo-p-dioxin on fusion of embryonic palates in serum-free organ culture using wild-type, EGF knockout, and TGFalpha knockout mouse strains.

B. Abbott, A. Buckalew, Korin E. Leffler, 2005, Birth defects research. Part A, Clinical and molecular teratology.

Teratogenic Impact of Dioxin Activated AHR in Laboratory Animals

B. Abbott, 2011 .

Human embryonic palatal epithelial differentiation is altered by retinoic acid and epidermal growth factor in organ culture.

B. Abbott, R. Pratt, 1987, Journal of craniofacial genetics and developmental biology.

Retinoids and epidermal growth factor alter embryonic mouse palatal epithelial and mesenchymal cell differentiation in organ culture.

B. Abbott, R. Pratt, 1987, Journal of craniofacial genetics and developmental biology.

Lack of expression of EGF and TGF-alpha in the fetal mouse alters formation of prostatic epithelial buds and influences the response to TCDD.

R. Peterson, R. Albrecht, B. Abbott, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Glucocorticoid receptor expression during the development of the embryonic mouse secondary palate.

C. Lau, B. Abbott, F. McNabb, 1994, Journal of craniofacial genetics and developmental biology.