A. Teti

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Tumor-stroma metabolic relationship based on lactate shuttle can sustain prostate cancer progression

Adriano Angelucci, Paola Chiarugi, Anna Teti, 2014, BMC Cancer.

Effective Small Interfering RNA Therapy to Treat CLCN7-dependent Autosomal Dominant Osteopetrosis Type 2

M. Capulli, A. Teti, A. Maurizi, 2015, Molecular therapy. Nucleic acids.

Recognition of osteopontin and related peptides by an alpha v beta 3 integrin stimulates immediate cell signals in osteoclasts.

S. Colucci, S. Teitelbaum, F. Ross, 1991, The Journal of biological chemistry.

Immediate cell signal by bone-related peptides in human osteoclast-like cells.

A. Zallone, S. Colucci, A. Teti, 1993, The American journal of physiology.

Phospholipase D- and protein kinase C isoenzyme-dependent signal transduction pathways activated by the calcitonin receptor.

D. Galson, S. Goldring, A. Teti, 1998, Endocrinology.

Binding of osteopontin to the osteoclast integrin αvβ3

S. Colucci, F. Ross, D. Cheresh, 2005, Osteoporosis International.

Chronic staphylococcal osteomyelitis: a new experimental rat model

A. Teti, P. Posteraro, L. Ciolli, 1993, Infection and immunity.

Osteoclast cytosolic calcium, regulated by voltage-gated calcium channels and extracellular calcium, controls podosome assembly and bone resorption

S. Colucci, R. Duncan, K. Hruska, 1990, The Journal of cell biology.

Tartronates: A New Generation of Drugs Affecting Bone Metabolism

R. Bertini, A. Teti, M. Allegretti, 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Isolation and Generation of Osteoclasts.

A. Zallone, A. Teti, N. Rucci, 2019, Methods in molecular biology.

A novel calcium sensor stimulating inositol phosphate formation and [Ca2+]i signaling expressed by GCT23 osteoclast-like cells.

K. Seuwen, A. Teti, S. Migliaccio, 2003, Proceedings of the Association of American Physicians.

New model for bone resorption study in vitro: Human osteoclast‐like cells from giant cell tumors of bone

A. Zallone, S. Colucci, K. Scotlandi, 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Extracellular Ca2+ sensing is modulated by pH in human osteoclast-like cells in vitro.

A. Zallone, S. Colucci, R. Faccio, 1994, The American journal of physiology.

Osteoblast-osteoclast relationships in bone resorption: osteoblasts enhance osteoclast activity in a serum-free co-culture system.

A. Zallone, S. Colucci, A. Teti, 1991, Biochemical and biophysical research communications.

Clear zone in osteoclast function: role of podosomes in regulation of bone-resorbing activity.

A. Zallone, A. Teti, P. Marchisio, 1991, The American journal of physiology.

Immediate cell signal induced by laminin in rat sertoli cells.

M. Stefanini, A. Teti, A. Taranta, 2000, Matrix biology : journal of the International Society for Matrix Biology.

Recent Advances in Mesenchymal Stem Cell Immunomodulation: The Role of Microvesicles

Anna Teti, A. Teti, A. Fierabracci, 2015, Cell transplantation.

Calcium release-activated calcium influx in cultured human mesangial cells.

A. Teti, F. Pugliese, P. Menè, 1994, Kidney international.

Impaired skeletal development in interleukin-6-transgenic mice: a model for the impact of chronic inflammation on the growing skeletal system.

A. Teti, N. Rucci, S. Ferrari, 2006, Arthritis and rheumatism.

pH dependence of neutrophil-endothelial cell adhesion and adhesion molecule expression.

J. Zweier, M. Capogrossi, T. Faraggiana, 1996, The American journal of physiology.

The "love-hate" relationship between osteoclasts and bone matrix.

A. Teti, N. Rucci, 2016, Matrix biology : journal of the International Society for Matrix Biology.

Lipocalin 2 serum levels correlate with age and bone turnover biomarkers in healthy subjects but not in postmenopausal osteoporotic women

S. Reppe, K. Gautvik, A. Teti, 2021, Bone reports.

Tissue inhibitor of metalloproteinase-2 protection of matrix metalloproteinase-2 from degradation by plasmin is reversed by divalent cation chelator EDTA and the bisphosphonate alendronate.

Antonella, A. Gulino, R. MacKay, 1998, Cancer research.

Characterization of the osteoblast‐like cell phenotype under microgravity conditions in the NASA‐approved rotating wall vessel bioreactor (RWV)

B. Zani, A. Teti, S. Migliaccio, 2002, Journal of cellular biochemistry.

Effect of vitamin a on bone resorption: Evidence for direct stimulation of isolated chicken osteoclasts by retinol and retinoic acid

A. Zallone, A. Teti, R. Oreffo, 1988, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Cytoplasmic pH regulation and chloride/bicarbonate exchange in avian osteoclasts.

P. Schlesinger, A. Teti, S. Teitelbaum, 1989, The Journal of clinical investigation.

CRELD2 Is a Novel LRP1 Chaperone That Regulates Noncanonical WNT Signaling in Skeletal Development

R. Boot-Handford, M. Capulli, A. Teti, 2020, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Genotype-phenotype relationship in human ATP6i-dependent autosomal recessive osteopetrosis.

R. Boldrini, G. Dini, E. Lanino, 2003, The American journal of pathology.

In vivo bone metastases, osteoclastogenic ability, and phenotypic characterization of human breast cancer cells.

E. Ricevuto, C. Ficorella, A. Teti, 2004, Bone.

Mechanisms Inducing Low Bone Density in Duchenne Muscular Dystrophy in Mice and Humans

E. Bertini, L. Morandi, M. Capulli, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Osteoblast-conditioned media stimulate membrane vesicle shedding in prostate cancer cells.

A. Angelucci, A. Teti, M. Bologna, 2006, International journal of oncology.

Biotechnological approach for systemic delivery of membrane Receptor Activator of NF-κB Ligand (RANKL) active domain into the circulation

M. Capulli, A. Teti, A. Maurizi, 2015, Biomaterials.

Osteoclasts: Essentials and Methods

A. Teti, N. Rucci, 2017 .

Osteomimicry: how tumor cells try to deceive the bone.

A. Teti, N. Rucci, 2010, Frontiers in bioscience.

Melanoma cells stimulate osteoclastogenesis, c-Src expression and osteoblast cytokines.

R. Baron, T. Faraggiana, A. Teti, 2001, European journal of cancer.

Inhibition of protein kinase c-Src as a therapeutic approach for cancer and bone metastases.

A. Teti, N. Rucci, M. Susa, 2008, Anti-cancer agents in medicinal chemistry.

Osteomimicry: How the Seed Grows in the Soil

A. Teti, N. Rucci, 2017, Calcified Tissue International.

Role of Stem Cell Niche in the Development of Bone Metastases (An Update)

A. Teti, N. Rucci, 2013 .

Ultrastructural evaluation of the microslicing method for the study of temporal bone pathology.

G. Bredberg, A. Teti, S. Iurato, 1987, Acta oto-laryngologica. Supplementum.

CHApTER 5 Functional polymorphisms within the infl ammatory pathway regulate expression of extracellular matrix components in a genetic risk dependent model for anterior cruciate ligament injuries

C. Häger, A. Teti, E. Stattin, 2019 .

Functional polymorphisms within the inflammatory pathway regulate expression of extracellular matrix components in a genetic risk dependent model for anterior cruciate ligament injuries.

C. Häger, D. Meuffels, A. Teti, 2019, Journal of science and medicine in sport.

Non-conventional role of haemoglobin beta in breast malignancy

A. Angelucci, P. Sanità, M. Capulli, 2017, British Journal of Cancer.

Oligodeoxynucleotide Targeted to the αv Gene Inhibits αv Integrin Synthesis, Impairs Osteoclast Function, and Activates Intracellular Signals to Apoptosis

R. Baron, M. Horton, P. Townsend, 1999 .

Transduction of arginine vasopressin signal in skeletal myogenic cells.

M. Molinaro, A. Teti, S. Adamo, 1993, The American journal of physiology.

An experimental therapy to improve skeletal growth and prevent bone loss in a mouse model overexpressing IL-6

M. Capulli, A. Teti, N. Rucci, 2014, Osteoporosis International.

The glycosaminoglycan-binding domain of PRELP acts as a cell type–specific NF-κB inhibitor that impairs osteoclastogenesis

D. Heinegård, E. Åhrman, M. Capulli, 2009, The Journal of cell biology.

β‐Arrestin2 Regulates RANKL and Ephrins Gene Expression in Response to Bone Remodeling in Mice

M. Bouxsein, M. Capulli, A. Teti, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Clinical, genetic, and cellular analysis of 49 osteopetrotic patients: implications for diagnosis and treatment

E. Lanino, N. Bishop, A. Teti, 2005, Journal of Medical Genetics.

Reduced growth and skeletal changes in zinc-deficient growing rats are due to impaired growth plate activity and inanition.

F. Branca, A. Teti, S. Migliaccio, 2001, The Journal of nutrition.

The osteoclasts of hen medullary bone under hypocalcaemic conditions

A. Zallone, A. Teti, Anna Teti, 2004, Anatomy and Embryology.

Resorption of vital or devitalized bone by isolated osteoclasts in vitro

A. Zallone, A. Teti, M. V. Primavera, 1984, Cell and Tissue Research.

Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro.

D. Fabbro, M. Šuša, A. Teti, 2003, European journal of cancer.

Tyrosine kinase src inhibitors: potential therapeutic applications.

M. Šuša, A. Teti, 2000, Drug news & perspectives.

Congenital disorders of bone and blood.

S. Teitelbaum, A. Teti, 2019, Bone.

Binding of osteopontin to the osteoclast integrin alpha v beta 3.

S. Colucci, F. Ross, D. Cheresh, 1993, Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA.

Beta 3 subunit of vitronectin receptor is present in osteoclast adhesion structures and not in other monocyte-macrophage derived cells.

A. Teti, P. Marchisio, M. Gaboli, 1989, Connective tissue research.

A New Heterozygous Mutation (R714C) of the Osteopetrosis Gene, Pleckstrin Homolog Domain Containing Family M (With Run Domain) Member 1 (PLEKHM1), Impairs Vesicular Acidification and Increases TRACP Secretion in Osteoclasts

J. Timmermans, A. Teti, S. Migliaccio, 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Austrian Bone Conference – ABC 2018

M. Capulli, A. Teti, S. Tangl, 2018, Wiener Medizinische Wochenschrift.

Bone and Blood

A. Teti, N. Rucci, 2019 .

Kinome profiling of osteoblasts on hydroxyapatite opens new avenues on biomaterial cell signaling.

M. Peppelenbosch, J. Granjeiro, A. Teti, 2014, Biotechnology and bioengineering.

Effects of advanced glycation end products on cytosolic Ca2+ signaling of cultured human mesangial cells.

A. Teti, F. Pugliese, P. Menè, 1999, Journal of the American Society of Nephrology : JASN.

Role of Neural (N)-Cadherin in Breast Cancer Cell Stemness and Dormancy in the Bone Microenvironment

A. Teti, A. Maurizi, M. Ciocca, 2022, Cancers.

Receptor activator of NF-kappaB ligand enhances breast cancer-induced osteolytic lesions through upregulation of extracellular matrix metalloproteinase inducer/CD147.

A. Angelucci, A. Teti, M. Bologna, 2010, Cancer research.

Modulation of human estrogen receptor alpha F promoter by a protein kinase C/c-Src-dependent mechanism in osteoblast-like cells.

A. Teti, S. Migliaccio, D. Fortunati, 2006, Journal of molecular endocrinology.

Osteopontin Modulates Prostate Carcinoma Invasive Capacity through RGD-Dependent Upregulation of Plasminogen Activators

A. Angelucci, A. Teti, M. Bologna, 2002, Biological chemistry.

An antisense oligonucleotide targeting the alphaV integrin gene inhibits adhesion and induces apoptosis in breast cancer cells.

R. Baron, M. Horton, P. Townsend, 2000, European journal of cancer.

Rous sarcoma virus-transformed fibroblasts and cells of monocytic origin display a peculiar dot-like organization of cytoskeletal proteins involved in microfilament-membrane interactions.

A. Teti, P. Marchisio, A. Zambonin-Zallone, 1987, Experimental cell research.

Osteoclasts and hematopoiesis.

A. Teti, 2012, BoneKEy reports.

Bone Cells: Osteoblast/Osteoclast/Osteocyte

A. Teti, N. Rucci, 2019, Encyclopedia of Endocrine Diseases.

The Role of the AlphaVbeta3 Integrin in the Development of Osteolytic Bone Metastases: A Pharmacological Target for Alternative Therapy?

R. Baron, A. Teti, S. Migliaccio, 2002, Calcified Tissue International.

Deregulation of the IL-1β axis in chronic recurrent multifocal osteomyelitis

A. Teti, F. De Benedetti, A. Insalaco, 2014, Pediatric Rheumatology.

The effect of microgravity on osteoblast metabolism

M. Capulli, A. Teti, N. Rucci, 2009 .

Tissue Inhibitor of Metalloproteinase-2 Protection of Matrix MetaIloproteinase-2 from Degradation by Plasmin Is Reversed by Divalent Cation Chelator EDTA and the Bisphosphonate Alendromite1

Antonella, A. Teti, Andrew, 2006 .

Tissue inhibitor of metalloproteinase-2 protection of matrix metalloproteinase-2 from degradation by plasmin is reversed by divalent cation chelator EDTA and the bisphosphonate alendronate.

A. Gulino, A. Teti, A. Farina, 1998, Cancer research.

The role of apoptosis associated speck-like protein containing a caspase-1 recruitment domain (ASC) in response to bone substitutes.

J. Granjeiro, A. Teti, A. Rossi, 2020, Materials science & engineering. C, Materials for biological applications.

A novel protein kinase C α-dependent signal to ERK1/2 activated by αVβ3 integrin in osteoclasts and in Chinese hamster ovary (CHO) cells

R. Baron, A. Teti, N. Rucci, 2005, Journal of Cell Science.

Imbalance of Osteoclastogenesis‐Regulating Factors in Patients With Celiac Disease

M. Bardella, A. Teti, S. Migliaccio, 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Integrins and other cell surface attachment molecules of bone cells

P. Marie, A. Teti, 2020, Principles of Bone Biology.

Regulation of cellular functions by extracellular matrix.

A. Teti, 1992, Journal of the American Society of Nephrology : JASN.

Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL

N. Bishop, A. Teti, A. Villa, 2007, Nature Genetics.

Interleukin-1β, lipocalin 2 and nitric oxide synthase 2 are mechano-responsive mediators of mouse and human endothelial cell-osteoblast crosstalk

M. Capulli, A. Teti, N. Rucci, 2016, Scientific Reports.

Colony Stimulating Factor‐1–Induced Osteoclast Spreading Depends on Substrate and Requires the Vitronectin Receptor and the c‐src Proto‐Oncogene

K. Hruska, T. Faraggiana, A. Teti, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Chloride Channel ClCN7 Mutations Are Responsible for Severe Recessive, Dominant, and Intermediate Osteopetrosis

L. Notarangelo, A. Flanagan, T. Young, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Anabolic and Antiresorptive Modulation of Bone Homeostasis by the Epigenetic Modulator Sulforaphane, a Naturally Occurring Isothiocyanate*

A. V. van Wijnen, A. Dudakovic, J. Zwerina, 2016, The Journal of Biological Chemistry.

Proline/arginine‐rich end leucine‐rich repeat protein N‐terminus is a novel osteoclast antagonist that counteracts bone loss

A. Angelucci, D. Heinegård, M. Capulli, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The ZNF687 mutation of Paget’s disease associated with giant cell tumour causes severe bone remodelling alteration as a result of a deregulated osteoclast transcriptional program

F. Gianfrancesco, A. Teti, A. Maurizi, 2022, bioRxiv.

New concepts in osteoclast pathophysiology

A. Teti, 2005 .

Osteoclasts and monocytes have similar cytoskeletal structures and adhesion property in vitro.

A. Zallone, L. Naldini, A. Teti, 1983, Journal of anatomy.

Rat testicular myoid cells respond to endothelin: characterization of binding and signal transduction pathway.

A. Filippini, E. Ziparo, F. Palombi, 1993, Endocrinology.

Calcitonin down-regulates immediate cell signals induced in human osteoclast-like cells by the bone sialoprotein-IIA fragment through a postintegrin receptor mechanism.

B. Zani, K. Scotlandi, A. Teti, 1995, Endocrinology.

Immunocytochemical distribution of extracellular matrix receptors in human osteoclasts: a beta 3 integrin is colocalized with vinculin and talin in the podosomes of osteoclastoma giant cells.

A. Teti, P. Marchisio, A. Rubinacci, 1989, Experimental cell research.

Activation of MMP‐2 by human GCT23 giant cell tumour cells induced by osteopontin, bone sialoprotein and GRGDSP peptides is RGD and cell shape change dependent

A. Chambers, A. Gulino, A. Teti, 1998, International journal of cancer.

Osteoblast‐derived TGFβ‐1 modulates matrix degrading protease expression and activity in prostate cancer cells

A. Angelucci, A. Albini, A. Teti, 2000 .

Osteoblast conditioned media contain TGF‐β1 and modulate the migration of prostate tumor cells and their interactions with extracellular matrix components

A. Angelucci, A. Teti, M. Bologna, 1999, International journal of cancer.

Novel C16orf57 mutations in patients with Poikiloderma with Neutropenia: bioinformatic analysis of the protein and predicted effects of all reported mutations

N. Elçioglu, J. Bazan, I. Altunay, 2012, Orphanet Journal of Rare Diseases.

Immunolocalization of beta 3 subunit of integrins in osteoclast membrane.

S. Colucci, A. Teti, A. Carano, 1989, Bollettino della Societa italiana di biologia sperimentale.

Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans.

J. Timmermans, A. Teti, A. Villa, 2007, The Journal of clinical investigation.

Early treatment of osteopetrosis: Paradigm shift to marrow cell transplantation.

A. Teti, 2022, Bone.

Osteopetroses, emphasizing potential approaches to treatment.

M. Econs, A. Teti, 2017, Bone.

Haematopoietic Stem Cell Transplantation in Autosomal Recessive Osteopetrosis

A. Schulz, A. Teti, 2013 .

The localization of thyroid hormone receptor mRNAs in human bone.

J. Compston, A. Teti, V. Chatterjee, 2000, Thyroid : official journal of the American Thyroid Association.

Circulating Extracellular Vesicles Express Receptor Activator of Nuclear Factor κB Ligand and Other Molecules Informative of the Bone Metabolic Status of Mouse Models of Experimentally Induced Osteoporosis

A. Teti, N. Rucci, M. Muraca, 2022, Calcified Tissue International.

Cell-Substratum Interaction of Cultured Avian Is Mediated by Specific Adhesion Structures Osteoclasts

L. Naldini, A. Teti, P. Marchisio, 2003 .

Transforming growth factor‐β enhances adhesion of melanoma cells to the endothelium in vitro

T. Faraggiana, A. Teti, S. Migliaccio, 1997, International journal of cancer.

Control of cytosolic free calcium in rat and chicken osteoclasts. The role of extracellular calcium and calcitonin.

J. Meldolesi, A. Zallone, A. Teti, 1989, The Journal of biological chemistry.

Extracellular protons acidify osteoclasts, reduce cytosolic calcium, and promote expression of cell-matrix attachment structures.

P. Schlesinger, K. Hruska, A. Teti, 1989, The Journal of clinical investigation.

Monocytes from circulating blood fuse in vitro with purified osteoclasts in primary culture.

A. Zallone, A. Teti, A. Zambonin Zallone, 1984, Journal of cell science.

Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases

A. Angelucci, L. Cosmi, F. Annunziato, 2005, Gene Therapy.

Acid phosphatase activity is stimulated in isolated osteoclasts by vitamin A.

A. Teti, R. Oreffo, M. Francis, 1986, Bollettino della Societa italiana di biologia sperimentale.

Osteoblast‐derived TGF‐β1 modulates matrix degrading protease expression and activity in prostate cancer cells

A. Angelucci, A. Teti, M. Bologna, 2000, International journal of cancer.

Modeled microgravity stimulates osteoclastogenesis and bone resorption by increasing osteoblast RANKL/OPG ratio

Anna Teti, A. Teti, N. Rucci, 2007, Journal of cellular biochemistry.

Insulin Signaling in Osteoblasts Integrates Bone Remodeling and Energy Metabolism

R. DePinho, G. Karsenty, A. Teti, 2010, Cell.

The Physiology and Pathophysiology of the Osteoclast

A. Teti, B. Peruzzi, 2012, Clinical Reviews in Bone and Mineral Metabolism.

Transcriptomic and bioinformatic analysis of Clcn7-dependent Autosomal Dominant Osteopetrosis Type 2 Preclinical and clinical implications.

A. Teti, A. Maurizi, N. Rucci, 2020, Bone.

Influence of calcium depletion on medullary bone of laying hens

A. Zallone, A. Teti, M. Zanetti, 2006, Calcified Tissue International.

Cell-substratum interaction of cultured avian osteoclasts is mediated by specific adhesion structures

L. Naldini, A. Teti, P. Marchisio, 1984, The Journal of cell biology.

Activation of inositol phospholipid turnover and calcium signaling in rat Sertoli cells by P2-purinergic receptors: modulation of follicle-stimulating hormone responses.

M. Conti, A. Filippini, E. Ziparo, 1994, Endocrinology.

Characterization and expression of different pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal polypeptide receptors in rat ovarian follicles.

M. Stefanini, A. Teti, S. Vaccari, 2006, The Journal of endocrinology.

Increase in cytosolic Ca2+ induced by elevation of extracellular Ca2+ in skeletal myogenic cells.

C. Reggiani, M. Molinaro, B. Zani, 2003, American journal of physiology. Cell physiology.

Collagen VII expression in glomerular sclerosis

T. Faraggiana, A. Teti, A. Onetti Muda, 2001, The Journal of pathology.

Calcitonin Increases Cytosolic Free Calcium Concentration via Capacitative Calcium Influx (*)

S. Goldring, A. Teti, Rossella Paniccia, 1995, The Journal of Biological Chemistry.

Protein kinase C affects microfilaments, bone resorption, and [Ca2+]o sensing in cultured osteoclasts.

A. Zallone, S. Colucci, A. Teti, 1992, The American journal of physiology.

Effects of Calcium-phosphate-based Materials on Proliferation and Alkaline Phosphatase Activity of Newborn Rat Periosteal Cells in vitro

S. Colucci, A. Teti, M. Grano, 1991, Journal of dental research.

Modulation of estrogen receptor levels in mouse uterus by protein kinase C isoenzymes.

W. Wetsel, K. Korach, A. Teti, 1998, Endocrinology.

Beta1 integrin antisense oligodeoxynucleotides: utility in controlling osteoclast function.

M. Horton, P. Townsend, A. Teti, 1999, European journal of cell biology.

The “GEnomics of Musculo Skeletal Traits TranslatiOnal NEtwork”: Origins, Rationale, Organization, and Prospects

F. Rivadeneira, C. Ohlsson, M. Brandi, 2021, Frontiers in Endocrinology.

P2RX7 Purinoceptor: A Therapeutic Target for Ameliorating the Symptoms of Duchenne Muscular Dystrophy

A. Teti, D. Górecki, G. Tozzi, 2015, PLoS medicine.

A six-gene signature predicting breast cancer lung metastasis.

Jean-Marc Guinebretière, Rosette Lidereau, Anna Teti, 2008, Cancer research.

Meeting report from the 24th annual meeting of the American society for bone and mineral research

D. Black, D. Vanderschueren, S. Ralston, 2002 .

The C‐Terminal Domain of Chondroadherin: A New Regulator of Osteoclast Motility Counteracting Bone Loss

K. Gautvik, D. Heinegård, O. K. Olstad, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The Great Beauty of the osteoclast.

A. Teti, A. Maurizi, Vimal Veeriah, 2014, Archives of biochemistry and biophysics.

NHERF1 acts as a molecular switch to program metastatic behavior and organotropism via its PDZ domains

A. Paradiso, M. Capulli, A. Teti, 2012, Molecular biology of the cell.

Immune Function and Diversity of Osteoclasts in Normal and Pathological Conditions

Anna Teti, A. Teti, F. Apparailly, 2019, Front. Immunol..

GutMicrobiota-derivedOuterMembrane Vesicles:UnderRecognizedMajorPlayers inHealthandDisease? MAu r Iz Io Mu r AcA , L or eNz A Pu t IgNANI , A LeSSANdr A FIer Abr AccI , ANNA t et I , ANd gIor gIo Per ILoNgo

G. Perilongo, L. Putignani, A. Teti, 2015 .

Decreased C-Src Expression Enhances Osteoblast Differentiation and Bone Formation

Silvia Bernardini, Roland Baron, Anna Teti, 2000, The Journal of cell biology.

Increased expression of a set of genes enriched in oxygen binding function discloses a predisposition of breast cancer bone metastases to generate metastasis spread in multiple organs

A. Angelucci, R. Lidereau, E. Ricevuto, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Expanding the role of Src and protein-tyrosine phosphatases balance in modulating osteoblast metabolism: lessons from mice.

A. Teti, W. Zambuzzi, Renato Milani, 2010, Biochimie.

The Crucial Role of c-Src Tyrosine Kinase in Bone Metabolism

A. Teti, N. Rucci, B. Peruzzi, 2012 .

Blocking Jak/STAT signalling using tofacitinib inhibits angiogenesis in experimental arthritis

A. Teti, A. Maurizi, N. Rucci, 2021, Arthritis Research & Therapy.

Do osteocytes contribute to bone mineral homeostasis? Osteocytic osteolysis revisited.

Anna Teti, A. Zallone, A. Teti, 2009, Bone.

Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to haematopoietic stem cell mimicry

Dayana Hristova, F. Masedu, M. Capulli, 2019, British Journal of Cancer.

Interaction of estrogen receptor α with protein kinase C α and c-Src in osteoblasts during differentiation

W. Wetsel, R. Baron, K. Korach, 2004 .

3 Osteoclast Genetic Diseases

A. Teti, A. D. Fattore, 2018 .

Osteoclast Genetic Diseases

A. Teti, A. D. Fattore, 2011 .

Genetics, pathogenesis and complications of osteopetrosis.

Anna Teti, A. Teti, Andrea Del Fattore, 2008, Bone.

Apparent Cure of a Newborn with Malignant Osteopetrosis Using Prednisone Therapy

A. Teti, S. Migliaccio, M. Iacobini, 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Apoptosis‐associated speck‐like protein containing a caspase‐1 recruitment domain (ASC) contributes to osteoblast differentiation and osteogenesis

J. Granjeiro, A. Teti, N. Rucci, 2018, Journal of cellular physiology.

Gut microbiota-derived outer membrane vesicles: under-recognized major players in health and disease?

G. Perilongo, L. Putignani, A. Teti, 2015, Discovery medicine.

Decreased proliferation and altered differentiation in osteoblasts from genetically and clinically distinct craniosynostotic disorders.

M. Tartaglia, A. Teti, S. Migliaccio, 1999, The American journal of pathology.

The α2β1 binding domain of chondroadherin inhibits breast cancer-induced bone metastases and impairs primary tumour growth: a preclinical study.

K. Gautvik, D. Heinegård, O. K. Olstad, 2015, Cancer letters.

Cytoplasmic pH is regulated in isolated avian osteoclasts by a Cl-/HCO3- exchanger.

P. Schlesinger, J. Kahn, A. Teti, 1989, Bollettino della Societa italiana di biologia sperimentale.

Reprint of: The Great Beauty of the osteoclast.

A. Teti, A. Maurizi, Vimal Veeriah, 2014, Archives of biochemistry and biophysics.

Bone metastasis: pathogenesis and therapeutic implications

Anna Teti, A. Teti, P. Clézardin, 2007, Clinical & Experimental Metastasis.

Type II Benign Osteopetrosis (Albers-Schönberg Disease) Caused by a Novel Mutation in CLCN7 Presenting with Unusual Clinical Manifestations

S. Ralston, A. Teti, S. Migliaccio, 2002, Calcified Tissue International.

Transient estrogen exposure of female mice during early development permanently affects osteoclastogenesis in adulthood.

K. Korach, A. Teti, R. Newbold, 2000, Bone.

Impaired gastric acidification negatively affects calcium homeostasis and bone mass

G. Sauter, A. Schulz, R. Simon, 2009, Nature Medicine.

Osteopenia, decreased bone formation and impaired osteoblast development in Sox4 heterozygous mice

S. Reppe, K. Gautvik, F. Reinholt, 2007, Journal of Cell Science.

Degeneration patterns in the organ of Corti and spiral lamina.

A. Teti, V. Balle, S. Iurato, 1987, Acta oto-laryngologica. Supplementum.

Microdissection, cytocochleogram and transmission electron microscopy: a technique for a comprehensive evaluation of human cochlear pathology.

A. Teti, G. Salomon, V. Balle, 1985, Acta oto-laryngologica. Supplementum.

CLCN7 and TCIRG1 Mutations Differentially Affect Bone Matrix Mineralization in Osteopetrotic Individuals

A. Schulz, U. Kornak, M. Hahn, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Osteoclast receptors and signaling.

A. Teti, N. Rucci, A. Del Fattore, 2008, Archives of biochemistry and biophysics.

Autoradiographic demonstration of in vitro fusion of blood monocytes with osteoclasts.

A. Teti, A. Zambonin Zallone, A. ZamboninZallone, 1985, Basic and applied histochemistry.

Metaplasic bone tissue in tympanosclerosis.

A. Teti, S. Iurato, A. Zambonin Zallone, 1983, Acta oto-laryngologica.

Inhibition of Protein Kinase c-Src Reduces the Incidence of Breast Cancer Metastases and Increases Survival in Mice: Implications for Therapy

D. Fabbro, A. Angelucci, M. Šuša, 2006, Journal of Pharmacology and Experimental Therapeutics.

Isolated osteoclasts in primary culture: first observations on structure and survival in culture media

A. Zallone, A. Teti, M. V. Primavera, 1982, Anatomy and Embryology.

Mechanisms of Osteoclast Dysfunction in Human Osteopetrosis: Abnormal Osteoclastogenesis and Lack of Osteoclast‐Specific Adhesion Structures

C. Bosman, R. Boldrini, A. Teti, 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Association of Intermediate Osteopetrosis with Poikiloderma

R. Boldrini, A. Teti, S. Migliaccio, 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Committed osteoclast precursors colonize the bone and improve the phenotype of a mouse model of autosomal recessive osteopetrosis

A. Ugazio, A. Teti, G. Bottazzo, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A mutation in the ZNF687 gene that is responsible for the severe form of Paget’s disease of bone causes severely altered bone remodeling and promotes hepatocellular carcinoma onset in a knock-in mouse model

F. Gianfrancesco, A. Teti, A. Maurizi, 2023, Bone Research.

Polymorphisms of the CLCN7 Gene Are Associated With BMD in Women

D. Reid, S. Ralston, A. Teti, 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

RNA interference therapy for autosomal dominant osteopetrosis type 2. Towards the preclinical development.

M. Capulli, A. Teti, A. Maurizi, 2018, Bone.

The effects of parathyroid hormone or 1,25-dihydroxyvitamin D3 on monocyte-osteoclast fusion

A. Zallone, A. Teti, A. Carano, 1988, Calcified Tissue International.

Extra-skeletal manifestations in mice affected by Clcn7-dependent autosomal dominant osteopetrosis type 2 clinical and therapeutic implications

M. Capulli, A. Teti, A. Maurizi, 2019, Bone Research.

Global transcriptome analysis in mouse calvarial osteoblasts highlights sets of genes regulated by modeled microgravity and identifies a “mechanoresponsive osteoblast gene signature”

Anna Teti, M. Capulli, A. Teti, 2009, Journal of cellular biochemistry.

Osteoblast-osteoclast interaction in bone resorption. Preliminary results.

S. Colucci, A. Teti, M. Grano, 1990, Bollettino della Societa italiana di biologia sperimentale.

Translocation of protein kinase C isoenzymes by elevated extracellular Ca2+ concentration in cells from a human giant cell tumor of bone.

J. Pfeilschifter, A. Huwiler, A. Teti, 1995, Bone.

Differentially expressed genes in autosomal dominant osteopetrosis type II osteoclasts reveal known and novel pathways for osteoclast biology

A. Teti, R. Olaso, Céline Baulard, 2014, Laboratory Investigation.

Osteoblast‐Derived Extracellular Vesicles Are Biological Tools for the Delivery of Active Molecules to Bone

A. Teti, A. Maurizi, N. Rucci, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Extracellular Vesicles From Osteotropic Breast Cancer Cells Affect Bone Resident Cells

A. Teti, N. Rucci, M. Muraca, 2020, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

c-Src and IL-6 inhibit osteoblast differentiation and integrate IGFBP5 signalling

A. Teti, N. Rucci, F. De Benedetti, 2012, Nature Communications.

Parathyroid hormone binding to cultured avian osteoclasts.

A. Teti, R. Rizzoli, A. Zambonin Zallone, 1991, Biochemical and biophysical research communications.

Lipocalin 2: A New Mechanoresponding Gene Regulating Bone Homeostasis

M. Heer, M. Capulli, A. Teti, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The selective estrogen receptor modulator raloxifene regulates osteoclast and osteoblast activity in vitro.

R. Scandurra, A. Teti, S. Migliaccio, 2002, Bone.

Bone cells and the mechanisms of bone remodelling.

A. Teti, N. Rucci, A. Del Fattore, 2012, Frontiers in bioscience.

The role of protein kinase C in the osteoclast activity.

S. Colucci, A. Teti, M. Grano, 1990, Bollettino della Societa italiana di biologia sperimentale.

The distribution of podosomes in osteoclasts cultured on bone laminae: Effect of retinol

A. Teti, P. Marchisio, A. Carano, 1988, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Tumorigenesis and Neoplastic Progression Kinase-Dependent and -Independent Roles of EphA2 in the Regulation of Prostate Cancer Invasion and Metastasis

E. Giannoni, A. Angelucci, P. Chiarugi, 2009 .

Suppression of EGF-R signaling reduces the incidence of prostate cancer metastasis in nude mice.

Adriano Angelucci, Anna Teti, A. Angelucci, 2006, Endocrine-related cancer.

Osteoblasts Regulate Angiogenesis in Response to Mechanical Unloading

M. Capulli, A. Teti, S. Chatterjee, 2018, Calcified Tissue International.

A Complex Role for Lipocalin 2 in Bone Metabolism: Global Ablation in Mice Induces Osteopenia Caused by an Altered Energy Metabolism

M. Capulli, A. Teti, T. Berger, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Mechanisms of osteoclast-dependent bone formation.

A. Teti, 2013, BoneKEy reports.

Macrophage-Derived Extracellular Vesicles as Carriers of Alarmins and Their Potential Involvement in Bone Homeostasis

A. Teti, F. V. D. van de Loo, P. V. van Lent, 2019, Front. Immunol..

Bone Development: Overview of Bone Cells and Signaling

A. Teti, 2011, Current osteoporosis reports.

Bone-targeted doxorubicin-loaded nanoparticles as a tool for the treatment of skeletal metastases.

A. Angelucci, S. Avnet, M. Salerno, 2010, Current cancer drug targets.

Osteoblasts modulate secretion of urokinase-type plasminogen activator (uPA) and matrix metalloproteinase-9 (MMP-9) in human prostate cancer cells promoting migration and matrigel invasion.

A. Angelucci, A. Albini, A. Teti, 1999, Oncology research.

Adhesion properties and integrin expression of cultured human osteoclast-like cells.

A. Zallone, L. Trusolino, S. Colucci, 1994, Experimental cell research.

New mechanisms of osteopetrosis

A. Teti, Marta Capannolo, A. D. Fattore, 2009 .

Evaluation of metastatic potential in prostate carcinoma: an in vivo model.

A. Angelucci, A. Teti, C. Vicentini, 2004, International journal of oncology.

Osteoclast Determinants and Implications for Therapy

A. Teti, 2013 .

Mature osteocytes behaviour in a repletion period: the occurrence of osteoplastic activity.

A. Teti, A. Zambonin Zallone, M. V. Primavera, 1983, Basic and applied histochemistry.

A novel protein kinase C alpha-dependent signal to ERK1/2 activated by alphaVbeta3 integrin in osteoclasts and in Chinese hamster ovary (CHO) cells.

R. Baron, A. Teti, N. Rucci, 2005, Journal of cell science.

Design of novel three-phase PCL/TZ–HA biomaterials for use in bone regeneration applications

S. Iannace, P. Netti, B. Dallapiccola, 2010, Journal of materials science. Materials in medicine.

Lipocalin 2 increases after high‐intensity exercise in humans and influences muscle gene expression and differentiation in mice

A. Teti, N. Rucci, G. Lombardi, 2021, Journal of cellular physiology.

Src as a Target for Pharmaceutical Intervention

M. Šuša, T. O'reilly, A. Teti, 2006 .

Reduction of c-Src activity by substituted 5,7-diphenyl-pyrrolo[2,3-d]-pyrimidines induces osteoclast apoptosis in vivo and in vitro. Involvement of ERK1/2 pathway.

D. Fabbro, M. Šuša, A. Teti, 2004, Bone.

Human prostatic tumor cells in culture produce growth and differentiation factors active on osteoblasts: a new biological and clinical parameter for prostatic carcinoma.

A. Teti, C. Vicentini, M. Bologna, 1997, Oncology research.

Interaction of estrogen receptor alpha with protein kinase C alpha and c-Src in osteoblasts during differentiation.

W. Wetsel, R. Baron, K. Korach, 2004, Bone.

Osteoclast bone resorption is enhanced in the presence of osteoblasts.

S. Colucci, A. Teti, F. Cantatore, 1990, Bollettino della Societa italiana di biologia sperimentale.

Osteoclasts - Meeting Report from the IBMS Davos Workshop: Bone Biology & Therapeutics: March 14-19, 2010 in Davos, Switzerland

A. Teti, 2010 .

Improvement of the skeletal phenotype in a mouse model of diastrophic dysplasia after postnatal treatment with N-acetylcysteine.

M. Capulli, A. Teti, A. Maurizi, 2021, Biochemical pharmacology.

Generation of the first autosomal dominant osteopetrosis type II (ADO2) disease models.

M. Econs, K. Mohammad, M. Capulli, 2014, Bone.

Lipocalin 2 Influences Bone and Muscle Phenotype in the MDX Mouse Model of Duchenne Muscular Dystrophy

A. Teti, A. Maurizi, N. Rucci, 2022, International journal of molecular sciences.

Protein Kinase C Modulates Estrogen Receptors in Differentiated Osteoblastic Cells In Vitro

W. Wetsel, K. Korach, T. Faraggiana, 1998, Steroids.

The tight relationship between osteoclasts and the immune system.

A. Teti, A. Del Fattore, 2012, Inflammation & allergy drug targets.

Advances in Brief Tissue Inhibitor of Metalloproteinase-2 Protection of Matrix MetaIloproteinase-2 from Degradation by Plasmin Is Reversed by Divalent Cation Chelator EDTA and the Bisphosphonate Alendromite 1

Antonella, R. MacKay, A. Teti, 2006 .