Zhigang Xu

发表

Discovery of 4 H ‐thieno[3,2‐ b ]pyrrole derivatives as potential anticancer agents

Bo Fang, Chunqiang Hu, Yong Ding, 2021 .

Strategy Used for Controlling the Photostability of Tridentate Pt(II) Complexes To Enhance the Device Lifetimes of Blue Phosphorescent Organic Light-Emitting Diodes: The Role of the Pt-C*(NHC) Bond and Auxiliary Ligand

Chun-he Fu, Yafei Luo, Zhigang Xu, 2018, The Journal of Physical Chemistry C.

Solvent‐Dependent Chemoselective and Stereoselective Approach to Synthesis of Spiro‐γ‐Lactams with Potent Anticancer Activity

Zhigang Xu, Zhong-Zhu Chen, Jingyuan Wen, 2021 .

Recent advances in the development of polycyclic skeletons via Ugi reaction cascades

Zhigang Xu, J. Meng, Zhong-Zhu Chen, 2018, Molecular Diversity.

Aldol reactions in multicomponent reaction based domino pathways: a multipurpose enabling tool in heterocyclic chemistry.

C. Hulme, Zhigang Xu, Fabio de Moliner, 2013, Organic letters.

Synthesis of Tetrazolo-Fused Benzodiazepines and Benzodiazepinones by a Two-Step Protocol Using an Ugi-Azide Reaction for Initial Diversity Generation.

C. Hulme, Zhigang Xu, B. Frett, 2012, Tetrahedron.

Synthesis of indoline-piperidinonesviaa novel Ugi, ring expansion,pseudo-Dieckmann condensation and rearrangement cascade reaction

Yafei Luo, Zhigang Xu, Zhong-Zhu Chen, 2020 .

Merging Visible Light with Cross-Coupling: The Photochemical Direct C-H Difluoroalkylation of Imidazopyridines.

Zhigang Xu, Zhong-Zhu Chen, Hong‐yu Li, 2019, Organic letters.

Ugi/Robinson-Gabriel reactions directed toward the synthesis of 2,4,5-trisubstituted oxazoles.

C. Hulme, A. Shaw, Zhigang Xu, 2012, Tetrahedron letters.

Tandem isonitrile insertion/azacyclopropylidene-annulated cyclohexenone–tropone rearrangement of p-QMs and TosMIC: de novo synthesis of pyrrolotropones with anti-cancer activity

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2021, Organic Chemistry Frontiers.

Two step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines.

Justin D Dietrich, C. Hulme, A. Shaw, 2010, Tetrahedron letters.

Investigate the Relationship between Structure and Triplet Potential Energy Surface to Control the Phosphorescence Quantum Yield of Platinum(II) Complex: A Theoretical Investigation.

Yafei Luo, Zhigang Xu, Zhong-Zhu Chen, 2022, Inorganic chemistry.

MIL-47(V) Catalytic Conversion of H2O2 for Sensitive H2O2 Detection and Tumor Cell Inhibition

Shu-juan Bao, Zhigang Xu, Yuyang Bai, 2021, Sensors and Actuators B: Chemical.

Synthesis of monofluorooxazoles with quaternary C-F centers through photoredox-catalyzed radical addition of methylene-2-oxazolines.

Zhigang Xu, Zhong-Zhu Chen, Chuanhua Qu, 2020, Organic & biomolecular chemistry.

Photoredox catalytic cascade radical addition/aromatization of methylene-2-oxazolines: Mild access to C(sp)-difluoro-oxazole derivatives

Zhigang Xu, J. Meng, Zhong-Zhu Chen, 2019, Tetrahedron Letters.

Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK.

Hui-Kuan Lin, Emily Lin, Zhigang Xu, 2021, Molecular cell.

Identification of pyrazine-based TrkA inhibitors: design, synthesis, evaluation, and computational modeling studies.

Zhigang Xu, Hong‐yu Li, Yuanxiang Wang, 2014, MedChemComm.

Functionalized Spiroindolines with Anticancer Activity through a Metal-Free Post-Ugi Diastereoselective One-Pot Cascade Reaction.

Zhigang Xu, J. Meng, Zhong-Zhu Chen, 2018, Chemistry.

A concise and unexpected one-pot methodology for the synthesis of pyrazinone-fused pyridones

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2020 .

Catalyst-Free One-Pot Synthesis of Densely Substituted Pyrazole-Pyrazines as Anti-Colorectal Cancer Agents

F. Zhan, Zhigang Xu, Zhong-Zhu Chen, 2020, Scientific Reports.

Two step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines.

Justin D Dietrich, C. Hulme, A. Shaw, 2010, Tetrahedron letters.

Acid-Promoted One-Pot Synthesis of Substituted Furan and 6-Methylpyrazin-2(1 H)-one Derivatives via Allene Intermediate Formed in Situ.

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2018, ACS combinatorial science.

Quantitative study of interactions between oxygen lone pair and aromatic rings: substituent effect and the importance of closeness of contact.

Zhigang Xu, Hong‐Cai Zhou, Shengqian Ma, 2008, The Journal of organic chemistry.

Blockading a new NSCLC immunosuppressive target by pluripotent autologous tumor vaccines magnifies sequential immunotherapy

Zhigang Xu, Hongyan Li, Chuan Xu, 2021, Bioactive materials.

A Decarboxylative C( sp 3 )−N Bond Forming Reaction to Construct 4‐Imidazolidinones via Post‐Ugi Cascade Sequence in One Pot

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2020 .

Benzimidazoisoquinoline derivatives inhibit glioblastoma cell proliferation through down-regulating Raf/MEK/ERK and PI3K/AKT pathways

Yan Tang, Zhigang Xu, Zhong-Zhu Chen, 2018, Cancer Cell International.

Strategy Used to Control Mechanism of Homogeneous Alkyne/Olefin Hydrogenation: AIMD Simulations and DFT Calculations.

Yafei Luo, Zhigang Xu, J. Meng, 2020, The Journal of organic chemistry.

Parallel Synthesis of Peptide-Like Macrocycles Containing Imidazole-4,5-dicarboxylic Acid

Zhigang Xu, P. Baures, K. Wheeler, 2012, Molecules.

Efficient microwave-assisted synthesis of fused benzoxazepine–isoquinoline derivatives via an Ugi reaction/tautomerization/intramolecular SNAr reaction sequence

Zhigang Xu, J. Meng, Zhong-Zhu Chen, 2017 .

Synthesis of isoindolin-1-one derivatives via multicomponent reactions of methyl 2-formylbenzoate and intramolecular amidation

Zhigang Xu, Zhong-Zhu Chen, J. Lei, 2016, Molecular Diversity.

Facile microwave-assisted synthesis of 1H-pyrazino[1,2-a]quinoxaline-1,5(6H)-dione derivatives via a nucleophilic substitution reaction

Zhigang Xu, Zhong-Zhu Chen, H. Cui, 2015, Science China Chemistry.

Microwave‐Assisted Construction of Pyrrolopyridinone Ring Systems by Using an Ugi/Indole Cyclization Reaction

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2016 .

Ugi/aldol sequence: expeditious entry to several families of densely substituted nitrogen heterocycles.

C. Hulme, Zhigang Xu, Fabio de Moliner, 2012, Angewandte Chemie.

An acid-catalyzed 1,4-addition isocyanide-based multicomponent reaction in neat water

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2020 .

Novel succinct routes to Quinoxalines and 2-Benzimidazolylquinoxalines via the Ugi reaction.

C. Hulme, Zhigang Xu, M. Ayaz, 2014, Tetrahedron letters.

Synthesis of fused benzimidazole–quinoxalinones via UDC strategy and following the intermolecular nucleophilic substitution reaction

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2014 .

General one-pot, two-step protocol accessing a range of novel polycyclic heterocycles with high skeletal diversity.

C. Hulme, Zhigang Xu, M. Ayaz, 2012, ACS combinatorial science.

Facile, novel two-step syntheses of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines

Justin D Dietrich, C. Hulme, A. Shaw, 2012, Molecular Diversity.

Facile microwave-assisted synthesis of benzimidazole scaffolds via Ugi-type three-component condensation (3CC) reactions

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2015, Molecular Diversity.

Synthesis of Constrained Heterocycles Employing Two Post-Ugi Cyclization Methods for Rapid Library Generation with In Cellulo Activity.

Zhigang Xu, Hong‐yu Li, Daekyu Sun, 2017, ChemistrySelect.

Expeditious access of chromone analogues via a Michael addition-driven multicomponent reaction

Yafei Luo, Zhigang Xu, Zhong-Zhu Chen, 2020 .

Facile synthesis and biological evaluation of tryptamine-piperazine-2,5-dione conjugates as anticancer agents

Zhigang Xu, J. Meng, Zhong-Zhu Chen, 2021, RSC advances.

An Efficient and Facile Method for the Synthesis of Benzimidazoisoquinoline Derivatives via a Multicomponent Reaction.

Jun Wang, Zhigang Xu, Zhong-Zhu Chen, 2016, ACS combinatorial science.

Structures and esterolytic reactivity of novel binuclear copper(ii) complexes with reduced l-serine Schiff bases as mimic carboxylesterases.

Zhigang Xu, Xiao-qiang Liu, Jun-Shi Shu, 2020, Dalton transactions.

Dieckmann Condensation of Ugi N-Acylamino Amide Product: Facile Access to Functionalized 2,2-Disubstituted Indolin-3-ones.

Yafei Luo, Zhigang Xu, J. Meng, 2021, The Journal of organic chemistry.

Strategy used to synthesize high activity and low Pd catalyst for Suzuki coupling reaction: an experimental and theoretical investigation.

Hubing Shi, Yafei Luo, Zhigang Xu, 2020, Physical chemistry chemical physics : PCCP.

One-pot synthesis of natural-product inspired spiroindolines with anti-cancer activities

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2022, Organic Chemistry Frontiers.

Microwave-assisted efficient and facile synthesis of tetramic acid derivatives via a one-pot post-Ugi cascade reaction

Yong Ding, Zhigang Xu, Zhong-Zhu Chen, 2020, Beilstein journal of organic chemistry.

Diversity-Oriented Synthesis of Functionalized Imidazopyridine Analogues with Anti-Cancer Activity through a Transition-Metal Free, One-pot Cascade Reaction

Zhigang Xu, Zhong-Zhu Chen, Hong‐yu Li, 2018, Advanced Synthesis & Catalysis.

Facile construction of fused benzimidazole-isoquinolinones that induce cell-cycle arrest and apoptosis in colorectal cancer cells.

Yan Tang, Hui-Kuan Lin, Zhigang Xu, 2018, Bioorganic & medicinal chemistry.

One-pot construction of functionalized aziridines and maleimides via a novel pseudo-Knoevenagel cascade reaction.

Yafei Luo, Zhigang Xu, Zhong-Zhu Chen, 2020, Chemical communications.

Microwave-Assisted Copper Catalysis of α-Difluorinated gem-Diol toward Difluoroalkyl Radical for Hydrodifluoroalkylation of para-Quinone Methides.

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2020, The Journal of organic chemistry.

Theoretical insights into ω-alkynylfuran cycloisomerisation catalyzed by Au/CeO2(111): the role of the CeO2(111) support

Yafei Luo, Zhigang Xu, Zhong-Zhu Chen, 2017 .

Computational Study on Cycloisomerization/Oxidative Dimerization of Aryl Propargyl Ethers Catalyzed by Gold Nanoclusters: Mechanism and Selectivity

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2014 .

Zn(OTf)2-Promoted Isocyanide-Based Three-Component Reaction: Direct Access to 2-Oxazolines and β-Amino Amides.

Yafei Luo, Zhigang Xu, Zhong-Zhu Chen, 2022, The Journal of organic chemistry.

(Z)-Stereoselective Synthesis of Mono- and Bis-heterocyclic Benzimidazol-2-ones via Cascade Processes Coupled with the Ugi Multicomponent Reaction.

C. Hulme, Zhigang Xu, S. Roberts, 2015, The Journal of organic chemistry.

Efficient and facile synthesis of fused benzimidazole-diazepinones and dibenzimidazole-diazepines via a UDC strategy and the hydroamination of an alkyne

Jun Wang, Zhigang Xu, Zhong-Zhu Chen, 2016 .

Acid-Promoted Direct C–H Carbamoylation at the C-3 Position of Quinoxalin-2(1H)-ones with Isocyanide in Water

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2022, ACS Omega.

Correction: One-pot construction of functionalized aziridines and maleimides via a novel pseudo-Knoevenagel cascade reaction.

Yafei Luo, Zhigang Xu, Zhong-Zhu Chen, 2020, Chemical communications.

3,5-Diaryl-1H-pyrazole as a molecular scaffold for the synthesis of apoptosis-inducing agents.

P. Lu, Chia-Ning Yang, A. Shaw, 2010, Bioorganic & medicinal chemistry.

Efficient method for the synthesis of fused benzimidazole–imidazoles via deprotection and cyclization reactions

Zhigang Xu, Zhong-Zhu Chen, Jin Zhang, 2015 .

Investigation of the Cycloisomerization of 1,6-Enynes Catalyzed by Gold Nanoparticles with First-Principles Calculations: Mechanism and Selectivity

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2014 .

Parallel synthesis of an oligomeric imidazole-4,5-dicarboxamide library.

Zhigang Xu, P. Baures, J. Dicesare, 2010, Journal of combinatorial chemistry.

Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS

Junbo Hu, F. Han, Hui-Kuan Lin, 2019, Cell.

Future perspective: high-throughput construction of new ultrasensitive cytokine and virion liquid chips for high-throughput screening (HTS) of anti-inflammatory drugs or clinical diagnosis and treatment of inflammatory diseases

Bochu Wang, Zhigang Xu, D. Tang, 2020, Analytical and Bioanalytical Chemistry.

Recent advances in the development of polycyclic skeletons via Ugi reaction cascades

Zhigang Xu, J. Meng, Zhong-Zhu Chen, 2018, Molecular Diversity.

CPI-613 rewires lipid metabolism to enhance pancreatic cancer apoptosis via the AMPK-ACC signaling

Yan Tang, Yong Teng, Manran Liu, 2020, Journal of experimental & clinical cancer research : CR.

Highly potent Platinum(IV) complexes with multiple-bond ligands targeting mitochondria to overcome cisplatin resistance.

Zhigang Xu, J. Meng, Cheng‐He Zhou, 2023, European journal of medicinal chemistry.

Photochemical diastereoselective synthesis and spectral characterization of (E)-3-(2-benzoylstyryl)-4H-chromen-4-ones

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2023, Journal of Molecular Structure.

A four-component domino reaction for the synthesis of novel bridgehead nitrogen-containing pyrido[1,2-d][1,4]diazepines

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2021, New Journal of Chemistry.

Catalyst-Free One-Pot Synthesis of Densely Substituted Pyrazole-Pyrazines as Anti-Colorectal Cancer Agents

F. Zhan, Zhigang Xu, Zhong-Zhu Chen, 2020, Scientific Reports.

One‐pot synthesis of benzimidazole‐pyrazines and their anticancer activities

Song Bai, Zhigang Xu, Xian Wei, 2019, Journal of Heterocyclic Chemistry.

Identification of myo-inositol-binding proteins by using the biotin pull-down strategy in cultured cells

Zhigang Xu, Zhong-Zhu Chen, J. Lei, 2022, STAR protocols.

Antiproliferative Evaluation of Novel 4-Imidazolidinone Derivatives as Anticancer Agent Which Triggers ROS-Dependent Apoptosis in Colorectal Cancer Cell

Zhigang Xu, Jiuhong Huang, Chuan Xu, 2022, Molecules.

Carrier-free nanomedicines self-assembled from palbociclib dimers and Ce6 for enhanced combined chemo-photodynamic therapy of breast cancer

Zhigang Xu, Dianyong Tang, Zheng Huang, 2023, RSC advances.

Benzimidazoisoquinoline derivatives inhibit glioblastoma cell proliferation through down-regulating Raf/MEK/ERK and PI3K/AKT pathways

Yan Tang, Zhigang Xu, Zhong-Zhu Chen, 2018, Cancer Cell International.

Discovery of fused benzimidazole-imidazole autophagic flux inhibitors for treatment of triple-negative breast cancer.

Zhigang Xu, Zhong-Zhu Chen, Jingyuan Wen, 2022, European journal of medicinal chemistry.

A Novel Imidazopyridine Derivative Exerts Anticancer Activity by Inducing Mitochondrial Pathway-Mediated Apoptosis

Hong Wu, Zhigang Xu, Donglin Yang, 2020, BioMed research international.

A cyclometalated (C^C*) platinum(II) NHC complex decorated via different carboranes to tune the photodeactivation mechanism: a theoretical investigation

Yafei Luo, Zhigang Xu, Zhong-Zhu Chen, 2016 .

Diversity-Oriented Synthesis of Imidazo-Dipyridines with Anticancer Activity via Groebke-Blackburn-Bienaymé and TBAB-Mediated Cascade Reaction in One Pot.

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2019, The Journal of organic chemistry.

Microwave-assisted facile construction of quinoxalinone and benzimidazopyrazinone derivatives via two paths of post-Ugi cascade reaction

Yong Ding, Zhigang Xu, Zhong-Zhu Chen, 2018, Molecular Diversity.

Applications of ortho-phenylisonitrile and ortho-N-Boc aniline for the two-step preparation of novel bis-heterocyclic chemotypes

C. Hulme, A. Shaw, Zhigang Xu, 2012, Molecular Diversity.

Facile, novel two-step syntheses of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines

Justin D Dietrich, C. Hulme, A. Shaw, 2012, Molecular Diversity.

Influence of restricted rotation of small-sized substituent on phosphorescence efficiency for Pt(II) complexes: A theoretical investigation

Chun-he Fu, Yafei Luo, Zhigang Xu, 2018, Organic Electronics.

Efficient Synthesis of Fused Oxazepino-isoquinoline Scaffolds via an Ugi, Followed by an Intramolecular Cyclization.

Zhigang Xu, J. Meng, Zhong-Zhu Chen, 2017, ACS combinatorial science.

Geometric Signatures as Important Factors to Control the Photo-Stabilities of the Phosphorescent Pd(II)/Pt(II) Complexes: A Case Study

Yafei Luo, Zhigang Xu, D. Tang, 2023, Molecules.

Lentivirus-mediated silencing of CNTN1 enhances gefitinib sensitivity by reversing epithelial-mesenchymal transition in lung adenocarcinoma A549 cells

Zhigang Xu, Zhong-Zhu Chen, Chuan Xu, 2021, Oncology letters.

Facile Construction of Hydantoin Scaffolds via a Post-Ugi Cascade Reaction

Yong Ding, Zhigang Xu, J. Meng, 2018, Synlett.

4-(Piperidin-1-yl)-4H-benzo[b]tetrazolo[1,5-d][1,4]diazepin-5(6H)-one

C. Hulme, Zhigang Xu, G. Nichol, 2010, Acta crystallographica. Section E, Structure reports online.

2-Propyl 3,3-dibromo-2-hydroxypyrrolidine-1-carboxylate

Justin D Dietrich, C. Hulme, Zhigang Xu, 2010, Acta crystallographica. Section E, Structure reports online.

Design of stable platinum(II) complexes exhibited various colors via auxiliary ligand and electron-donating/withdrawing groups: A theoretical investigation

Chun-he Fu, Yafei Luo, Zhigang Xu, 2019, Organic Electronics.

DFT insight into Hashmi phenol synthesis catalyzed by Au single-walled nanotubes: mechanism and charge effect

Yafei Luo, Zhigang Xu, Zhong-Zhu Chen, 2021, Theoretical Chemistry Accounts.

Visible Light‐Mediated Construction of Sulfonated Dibenzazepines

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2021 .

Facile microwave-assisted synthesis of benzimidazole scaffolds via Ugi-type three-component condensation (3CC) reactions

Zhigang Xu, Zhong-Zhu Chen, D. Tang, 2016, Molecular Diversity.

Silver-Catalyzed Decarboxylative Acylation of Isocyanides Accesses to α-Ketoamides with Air as a Sole Oxidant

Zhigang Xu, Zhong-Zhu Chen, J. Lei, 2023, Molecules.

Microwave-assisted synthesis of fused piperazine-benzimidazoles via a facile, one-pot procedure

Zhigang Xu, Zhong-Zhu Chen, Jianyong Yuan, 2015 .

Theoretical insights into acetylene adsorption on nanoporous gold surfaces: Role of residual silver

Yafei Luo, Zhigang Xu, Zhong-Zhu Chen, 2018 .

DMAPT‑D6 induces death‑receptor‑mediated apoptosis to inhibit glioblastoma cell oncogenesis via induction of DNA damage through accumulation of intracellular ROS.

Zhigang Xu, Zhong-Zhu Chen, Jiuhong Huang, 2021, Oncology Report.

An Efficient Synthesis of Naphtho[2,3-b]furan-4,9-diones via Visible-Light-Mediated [3+2] Cycloaddition Reaction

Bochu Wang, Zhigang Xu, D. Tang, 2023, Molecules.

Visible-light-mediated synthesis, NMR analysis and X-ray crystal structure of naphtho[2,3-b]furan-4,9-diones

Zhigang Xu, D. Tang, Y. Xiang, 2023, Journal of Molecular Structure.

NSUN2 is a glucose sensor suppressing cGAS/STING to maintain tumorigenesis and immunotherapy resistance.

Y. Tsai, P. Tsai, Zhigang Xu, 2023, Cell metabolism.

DMAPT‑D6 induces death‑receptor‑mediated apoptosis to inhibit glioblastoma cell oncogenesis via induction of DNA damage through accumulation of intracellular ROS

Zhigang Xu, Zhong-Zhu Chen, Jiuhong Huang, 2021 .

Copper-Catalyzed Synthesis of Furo[3,2-c]coumarins and Dihydrofuro[3,2-c]coumarins through a Propargylation/Alkyne Oxacyclization/Isomerization Cascade under Microwave Irradiation

Zhigang Xu, Zhong-Zhu Chen, H. Cui, 2015, Synlett.

Unexpected Cascade Sequence Forming the C(sp3)-N/C(sp2)-C(sp2) Bond: Direct Access to γ-Lactam-Fused Pyridones with Anticancer Activity.

Zhigang Xu, Zhong-Zhu Chen, J. Lei, 2023, The Journal of organic chemistry.