O. Pedersen

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Expression of protein‐tyrosine phosphatases in the major insulin target tissues

O. Pedersen, H. Vestergaard, N. Møłler, 1997, FEBS letters.

Alpha 2-adrenergic binding and action in human adipocytes. Comparison between binding to plasma membrane preparations and to intact adipocytes.

O. Pedersen, B. Richelsen, 1985, European journal of pharmacology.

Evidence Against Altered Expression of GLUT1 or GLUT4 in Skeletal Muscle of Patients With Obesity or NIDDM

J. Flier, D. Moller, B. Kahn, 1990, Diabetes.

Effect of endurance training on glucose transport capacity and glucose transporter expression in rat skeletal muscle.

T. Ohkuwa, B. Kahn, H. Galbo, 1990, The American journal of physiology.

Comparative effects of IGF-I and insulin on the glucose transporter system in rat muscle.

O. Pedersen, O. Schmitz, A. Flyvbjerg, 1994, The American journal of physiology.

Elevation of Serum Insulin Concentration During Euglycemic Hyperinsulinemic Clamp Studies Leads to Similar Activation of Insulin Receptor Kinase in Skeletal Muscle of Subjects With and Without NIDDM

H. Klein, H. Vestergaard, O. Pedersen, 1995, Diabetes.

Contraction stimulates translocation of glucose transporter GLUT4 in skeletal muscle through a mechanism distinct from that of insulin.

O. Pedersen, O. Schmitz, S. Lund, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Use of a novel impermeable biotinylated photolabeling reagent to assess insulin- and hypoxia-stimulated cell surface GLUT4 content in skeletal muscle from type 2 diabetic patients.

J. Zierath, D. Galuska, H. Wallberg-henriksson, 2000, Diabetes.

Insulin Action and Insulin Secretion in Identical Twins With MODY: Evidence for Defects in Both Insulin Action and Secretion

H. Beck-Nielsen, O. Pedersen, O. Schmitz, 1988, Diabetes.

Expression of glycogen synthase and phosphofructokinase in muscle from Type 1 (insulin-dependent) diabetic patients before and after intensive insulin treatment

H. Vestergaard, O. Pedersen, S. Lund, 2004, Diabetologia.

Gliclazide and insulin action in human muscle.

O. Pedersen, J. Bak, 1991, Diabetes research and clinical practice.

Defective Non‐insulin‐mediated and Insulin‐mediated Glucose Transport and Metabolism in Adipocytes from Obese and Lean Patients with Untreated Type 2 Diabetes Mellitus

H. Beck-Nielsen, O. Pedersen, B. Richelsen, 1985, Diabetic medicine : a journal of the British Diabetic Association.

Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner.

O. Pedersen, N. Jessen, S. Pedersen, 2001, Diabetes.

Impaired insulin-stimulated nonoxidative glucose metabolism in glucose-tolerant women with previous gestational diabetes.

H. Vestergaard, P. Damm, O. Pedersen, 1996, American journal of obstetrics and gynecology.

Metformin improves peripheral but not hepatic insulin action in obese patients with type II diabetes.

H. Beck-Nielsen, O. Hother-Nielsen, O. Pedersen, 1989, Acta endocrinologica.

Increased insulin sensitivity and cellular insulin binding in obese diabetics following treatment with glibenclamide.

H. Beck-Nielsen, O. Pedersen, H. Lindskov, 1979, Acta endocrinologica.

Effects of dietary changes on cellular insulin binding and in vivo insulin sensitivity.

H. Beck-Nielsen, O. Pedersen, N. Sørensen, 1980, Metabolism: Clinical and Experimental.

The effect of glibenclamide on insulin receptors in normal man: comparative studies of insulin binding to monocytes and erythrocytes.

H. Beck-Nielsen, O. Pedersen, B. Richelsen, 1983, The Journal of clinical endocrinology and metabolism.

Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients.

T. Hansen, H. Vestergaard, D. Granner, 1995, The Journal of clinical investigation.

Expression of GLUT1 and GLUT4 glucose transporters in skeletal muscle of humans with insulin-dependent diabetes mellitus: regulatory effects of metabolic factors.

B. Kahn, O. Pedersen, S. Lund, 1992, The Journal of clinical endocrinology and metabolism.

Insulin Resistance and Insulin-Dependent Diabetes Mellitus

H. Beck-Nielsen, O. Pedersen, 1987, Diabetes Care.

Insulin Receptor Assays Used in Human Studies: Merits and Limitations

O. Pedersen, 1983, Diabetes Care.

Mechanism of Action of Sulphonylureas with Special Reference to the Extrapancreatic Effect: An Overview

H. Beck-Nielsen, O. Hother-Nielsen, O. Pedersen, 1988, Diabetic medicine : a journal of the British Diabetic Association.

Insulin Receptor Binding to Fat and Blood Cells and Insulin Action in Fat Cells from Insulin-dependent Diabetics

O. Pedersen, E. Hjøllund, Elisabeth Hjøllund, 1982, Diabetes.

Effects of glipizide on glucose metabolism and muscle content of the insulin-regulatable glucose transporter (GLUT 4) and glycogen synthase activity during hyperglycaemia in type 2 diabetic patients

N. Møller, O. Pedersen, O. Schmitz, 1994, Acta Diabetologica.

The plasma C-peptide and insulin responses to stimulation with intravenous glucagon and a mixed meal in well-controlled Type 2 (non-insulin-dependent) diabetes mellitus: dependency on acutely established hyperglycaemia

O. Pedersen, H. Gjessing, B. Reinholdt, 1989, Diabetologia.

Studies of insulin resistance in congenital generalized lipodystrophy *

O. Søvik, H. Vestergaard, O. Pedersen, 1996, Acta paediatrica (Oslo, Norway : 1992). Supplement.

Severe insulin-resistant diabetes mellitus in patients with congenital muscle fiber type disproportion myopathy.

T. Hansen, H. Klein, H. Vestergaard, 1995, The Journal of clinical investigation.

Insulin-resistant glucose metabolism in patients with microvascular angina--syndrome X.

J. Kastrup, H. Vestergaard, O. Pedersen, 1995, Metabolism: clinical and experimental.

Whole‐body Glucose Metabolism in Obese Patients with Type 2 Diabetes Mellitus: the Impact of Hypertension and Strict Blood Glucose Control

H. Parving, H. Vestergaard, O. Pedersen, 1995, Diabetic medicine : a journal of the British Diabetic Association.

Expression of insulin receptor spliced variants and their functional correlates in muscle from patients with non-insulin-dependent diabetes mellitus.

T. Hansen, H. Vestergaard, O. Pedersen, 1993, The Journal of clinical endocrinology and metabolism.

The effect of acute hyperglycemia on the plasma C-peptide response to intravenous glucagon or to a mixed meal in insulin-dependent diabetes mellitus.

O. Pedersen, O. Faber, H. Gjessing, 1991, Acta endocrinologica.

In vivo insulin action and muscle glycogen synthase activity in Type 2 (non-insulin-dependent) diabetes mellitus: effects of diet treatment

N. Møller, O. Pedersen, O. Schmitz, 1992, Diabetologia.

Effects of hyperinsulinemia and hyperglycemia on insulin receptor function and glycogen synthase activation in skeletal muscle of normal man.

E. Richter, N. Møller, O. Pedersen, 1991, Metabolism: clinical and experimental.

Postbinding defects of insulin action in human adipocytes from uremic patients.

H. E. Hansen, O. Pedersen, B. Richelsen, 1985, Kidney international.

Effects of perindopril on insulin sensitivity and plasma lipid profile in hypertensive non-insulin-dependent diabetic patients.

O. Pedersen, L. U. Gerdes, J. Bak, 1992, The American journal of medicine.

Impaired cellular insulin binding and insulin sensitivity induced by high-fructose feeding in normal subjects.

H. Beck-Nielsen, O. Pedersen, H. Lindskov, 1980, The American journal of clinical nutrition.

Effect of Insulin on GLUT4 Cell Surface Content and Turnover Rate in Human Skeletal Muscle as Measured by the Exofacial Bis-Mannose Photolabeling Technique

J. Zierath, H. Wallberg-henriksson, L. Nolte, 1997, Diabetes.

Pre- and posttranslational upregulation of muscle-specific glycogen synthase in athletes.

H. Vestergaard, O. Pedersen, O. Schmitz, 1994, The American journal of physiology.

Decreased hepatic glucagon responses in Type 1 (insulin-dependent) diabetes mellitus

K. Alberti, N. Møller, O. Pedersen, 1991, Diabetologia.

Glut 4 content in the plasma membrane of rat skeletal muscle: comparative studies of the subcellular fractionation method and the exofacial photolabelling technique using ATB‐BMPA

O. Pedersen, O. Schmitz, S. Lund, 1993, FEBS letters.

Glucose transport and metabolism in adipocytes from newly diagnosed untreated insulin-dependent diabetics. Severely impaired basal and postinsulin binding activities.

H. Beck-Nielsen, O. Pedersen, B. Richelsen, 1985, The Journal of clinical investigation.

Increased insulin receptors after exercise in patients with insulin-dependent diabetes mellitus.

H. Beck-Nielsen, O. Pedersen, L. Heding, 1980, The New England journal of medicine.

Insulin receptor binding and insulin action in human fat cells: effects of obesity and fasting.

O. Pedersen, E. Hjøllund, N. Sørensen, 1982, Metabolism: clinical and experimental.

The Effects of Metformin on Adipocyte Insulin Action and Metabolic Control in Obese Subjects with Type 2 Diabetes

H. Beck-Nielsen, O. Pedersen, B. Richelsen, 1989, Diabetic medicine : a journal of the British Diabetic Association.

Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes

O. Pedersen, L. Dalgaard, O. Pedersen, 2001, Diabetologia.

GLUT-4 content in plasma membrane of muscle from patients with non-insulin-dependent diabetes mellitus.

H. Vestergaard, O. Pedersen, O. Schmitz, 1993, The American journal of physiology.

Acute Actions of Sulfonylurea Drugs During Long-Term Treatment of NIDDM

H. Beck-Nielsen, O. Pedersen, A. Melander, 1990, Diabetes Care.

Rosiglitazone treatment of patients with extreme insulin resistance and diabetes mellitus due to insulin receptor mutations has no effects on glucose and lipid metabolism

H. Vestergaard, O. Pedersen, S. Lund, 2001, Journal of internal medicine.

The Effect of Intensive Insulin Therapy on the Insulin‐regulatable Glucose Transporter (GLUT4) Expression in Skeletal Muscle in Type 1 Diabetes

H. Vestergaard, B. Kahn, O. Pedersen, 1993, Diabetic medicine : a journal of the British Diabetic Association.

Divergent regulation of the Glut 1 and Glut 4 glucose transporters in isolated adipocytes from Zucker rats.

C. Kahn, B. Kahn, O. Pedersen, 1992, The Journal of clinical investigation.

High fat feeding causes insulin resistance and a marked decrease in the expression of glucose transporters (Glut 4) in fat cells of rats.

C. Kahn, J. Flier, B. Kahn, 1991, Endocrinology.

Suppression of GLUT4 expression in skeletal muscle of rats that are obese from high fat feeding but not from high carbohydrate feeding or genetic obesity.

B. Kahn, O. Pedersen, Barbara B. Kahn, 1993, Endocrinology.

Impaired Insulin Receptor Binding and Postbinding Defects of Adipocytes From Normal and Diabetic Pregnant Women

O. Pedersen, J. Klebe, E. Hjøllund, 1986, Diabetes.

Effect of physical training on glucose transporter protein and mRNA levels in rat adipocytes.

L. Bendtsen, H. Galbo, J. Vinten, 1993, The American journal of physiology.

Increased insulin binding to adipocytes and monocytes and increased insulin sensitivity of glucose transport and metabolism in adipocytes from non-insulin-dependent diabetics after a low-fat/high-starch/high-fiber diet.

H. Beck-Nielsen, O. Pedersen, B. Richelsen, 1983, Metabolism: clinical and experimental.

In vivo action of glibenclamide in obese subjects with mild type 2 (non-insulin dependent) diabetes.

H. Beck-Nielsen, O. Hother-Nielsen, O. Pedersen, 1988, Diabetes research.

A Mixed Meal Potentiates the Insulin Sensitivity of Glucose Transport and Metabolism in Adipocytes from Patients with Type 2 Diabetes Mellitus

O. Pedersen, B. Richelsen, P. Andersen, 1988, Diabetic medicine : a journal of the British Diabetic Association.

Diurnal profile of pancreatic polypeptide, pancreatic glucagon, gut glucagon and insulin in human morbid obesity.

J. Holst, T. Schwartz, H. Beck-Nielsen, 1983, International journal of obesity.

Short- and long-term metabolic effects of recombinant human IGF-I treatment in patients with severe insulin resistance and diabetes mellitus.

H. Vestergaard, O. Pedersen, S. Urhammer, 1997, European journal of endocrinology.

Increased Insulin Receptor Binding to Monocytes from Insulu-dependent Diabetic Patients After a Low-Fat, High-Starch, High-Fiber Diet

O. Pedersen, P. Helms, J. Ditzel, 1982, Diabetes Care.

A study of insulin receptors in human mononuclear leucocytes.

H. Beck-Nielsen, O. Pedersen, 1976, Acta endocrinologica.

Effects of sulfonylureas on adipocyte and skeletal muscle insulin action in patients with non-insulin-dependent diabetes mellitus.

H. Beck-Nielsen, O. Hother-Nielsen, O. Pedersen, 1991, The American journal of medicine.

Decreased binding of insulin to its receptor in patients with congenital generalized lipodystrophy.

O. Søvik, H. Beck-Nielsen, O. Pedersen, 1977, The New England journal of medicine.

Insulin Receptors on Monocytes from Patients with Ketosis-prone Diabetes Mellitus

H. Beck-Nielsen, O. Pedersen, L. Heding, 1978, Diabetes.

Exercise-enhanced activation of glycogen synthase in human skeletal muscle.

O. Pedersen, J. Bak, 1990, The American journal of physiology.

EFFECTS OF EXERCISE ON INSULIN RECEPTORS ON ERYTHROCYTES AND MONOCYTES FROM INSULIN DEPENDENT DIABETICS

H. Beck-Nielsen, O. Pedersen, L. Heding, 1980, Acta paediatrica Scandinavica. Supplement.

Insulin binding and action on fat cells from young healthy females and males.

O. Pedersen, E. Hjøllund, H. Lindskov, 1982, The American journal of physiology.

Circadian profiles of insulin receptors in insulin-dependent diabetics in usual and poor metabolic control.

H. Beck-Nielsen, O. Pedersen, J. Jensen, 1982, The American journal of physiology.

Transport and metabolism of D-glucose in human adipocytes. Studies of the dependence on medium glucose and insulin concentrations.

O. Pedersen, E. Hjøllund, 1988, Biochimica et biophysica acta.

Serum leptin levels in pregnant women with type 1 diabetes mellitus

H. Vestergaard, O. Pedersen, O. Schmitz, 2001, Acta obstetricia et gynecologica Scandinavica.

Multiple insulin injections using a pen injector versus insulin pump treatment in young diabetic patients.

H. Beck-Nielsen, O. Pedersen, J. Bak, 1987, Diabetes research.

Effects of diet on the cellular insulin binding and the insulin sensitivity in young healthy subjects

H. Beck-Nielsen, O. Pedersen, N. Schwartz Sørensen, 1978, Diabetologia.

Insulin binding, insulin degradation and glucose metabolism in human monocytes

H. Beck-Nielsen, O. Pedersen, 1979, Diabetologia.

The monocyte as a model for the study of insulin receptors in man

H. Beck-Nielsen, K. Kragballe, O. Pedersen, 1977, Diabetologia.

Normalization of the insulin sensitivity and the cellular insulin binding during treatment of obese diabetics for one year.

H. Beck-Nielsen, O. Pedersen, H. Lindskov, 1979, Acta endocrinologica.

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus

T. Hansen, S. Echwald, K. Almind, 1993, The Lancet.

Prostaglandin E2 receptor binding and action in human fat cells.

H. Beck-Nielsen, O. Pedersen, B. Richelsen, 1984, The Journal of clinical endocrinology and metabolism.

Influence of short-term dexfenfluramine therapy on glucose and lipid metabolism in obese non-diabetic patients.

O. Pedersen, B. Richelsen, O. Schmitz, 1993, Acta endocrinologica.

Insulin receptors on monocytes of young healthy persons correlated with glucose tolerance and insulin sensitivity

H. Beck-Nielsen, O. Pedersen, 1978, Diabetologia.

Increased insulin binding is not involved in the improved insulin effectiveness of gestational diabetics after hypoenergetic dieting.

H. Beck-Nielsen, O. Pedersen, B. Richelsen, 1985, Diabetes research and clinical practice.

Heterogeneity of insulin receptors in patients with untreated insulin-dependent diabetes mellitus.

H. Beck-Nielsen, O. Pedersen, N. S. Sørensen, 1982, The Journal of clinical endocrinology and metabolism.

Insulin receptors in the pregnant diabetic and her newborn.

H. Beck-Nielsen, O. Pedersen, J. Klebe, 1981, The Journal of clinical endocrinology and metabolism.

Prednisone increases the number of insulin receptors on monocytes from normal subjects.

H. Beck-Nielsen, O. Pedersen, R. De Pirro, 1980, The Journal of clinical endocrinology and metabolism.

Decreased insulin binding to monocytes from normal pregnant women.

T. Nielsen, H. Beck-Nielsen, O. Pedersen, 1979, The Journal of clinical endocrinology and metabolism.

Diurnal variation in insulin binding to human monocytes.

H. Beck-Nielsen, O. Pedersen, 1978, The Journal of clinical endocrinology and metabolism.

Evidence against protein kinase B as a mediator of contraction‐induced glucose transport and GLUT4 translocation in rat skeletal muscle

S. Østergaard, O. Pedersen, O. Schmitz, 1998, FEBS letters.

Sulfonylurea therapy improves glucose disposal without changing skeletal muscle GLUT4 levels in noninsulin-dependent diabetes mellitus subjects: a longitudinal study.

H. Vestergaard, B. Kahn, O. Pedersen, 1995, The Journal of clinical endocrinology and metabolism.

Sulfonylureas improve insulin binding and insulin action in non-insulin-dependent diabetes mellitus.

H. Beck-Nielsen, O. Pedersen, B. Richelsen, 1984, Diabetes care.

Unchanged gene expression of glycogen synthase in muscle from patients with NIDDM following sulphonylurea-induced improvement of glycaemic control

O. Pedersen, H. Vestergaard, O. Pedersen, 1995, Diabetologia.

Implications of compound heterozygous insulin receptor mutations in congenital muscle fibre type disproportion myopathy for the receptor kinase activation

H. Klein, H. Vestergaard, O. Pedersen, 1999, Diabetologia.

The Effect of Chronic Hyperglycaemia on the Islet B‐cell Responsiveness in Newly Diagnosed Type 2 Diabetes

O. Pedersen, H. Gjessing, B. Reinhold, 1992, Diabetic medicine : a journal of the British Diabetic Association.

Insulin receptor function and glycogen synthase activity in skeletal muscle biopsies from patients with insulin-dependent diabetes mellitus: effects of physical training.

O. Pedersen, J. Bak, F. S. Jørgensen, 1989, The Journal of clinical endocrinology and metabolism.

Diabetes mellitus caused by insulin-receptor blockade and impaired sensitivity to insulin.

H. Beck-Nielsen, O. Pedersen, E. Hjøllund, 1981, The New England journal of medicine.

Insulin receptor binding and receptor-mediated insulin degradation in human adipocytes

H. Beck-Nielsen, O. Pedersen, J. Gliemann, 1981, Diabetologia.

The insulin receptor in normal and obese persons.

H. Beck-Nielsen, O. Pedersen, J. Bagger, 1976, Acta endocrinologica.

Effects of prostaglandin E2, indomethacin and adenosine deaminase on basal and insulin-stimulated glucose metabolism in human adipocytes.

O. Pedersen, B. Richelsen, E. Hjøllund, 1985, Biochimica et biophysica acta.

Hexose transport in human adipocytes: Factors influencing the response to insulin and kinetics of methylglucose and glucose transport

O. Pedersen, J. Gliemann, 1981, Diabetologia.

Monocyte-mediated antibody-dependent cytotoxicity. Modulation by Glycolysis and insulin.

H. Beck-Nielsen, K. Kragballe, O. Pedersen, 2009, Scandinavian journal of haematology.

Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1

T. Hansen, K. Almind, K. Borch-Johnsen, 1995, The Lancet.

Glycogen synthase and phosphofructokinase protein and mRNA levels in skeletal muscle from insulin-resistant patients with non-insulin-dependent diabetes mellitus.

H. Vestergaard, O. Pedersen, S. Lund, 1993, The Journal of clinical investigation.

Metformin may adversely affect orthostatic blood pressure recovery in patients with type 2 diabetes: substudy from the placebo-controlled Copenhagen Insulin and Metformin Therapy (CIMT) trial

A. Vaag, L. Tarnow, H. Vestergaard, 2020, Cardiovascular Diabetology.

Limitations in the use of insulin or C-peptide alone in the assessment of beta-cell function in pancreas transplant recipients. Danish-Swedish Study Group of Metabolic Effect of Pancreas Transplantation.

O. Pedersen, N. Christensen, S. Madsbad, 1994, Transplantation proceedings.

Reduced binding and antilipolytic effect of prostaglandin E2 in adipocytes from patients with hyperthyroidism.

O. Pedersen, B. Richelsen, N. S. Sørensen, 1986, The Journal of clinical endocrinology and metabolism.

Increased insulin-stimulated glucose uptake in athletes: the importance of GLUT4 mRNA, GLUT4 protein and fibre type composition of skeletal muscle.

B. Kahn, O. Pedersen, O. Schmitz, 1993, Acta physiologica Scandinavica.

Tissue-Specific Regulation of Glucose Transporters in Different Forms of Obesity

B. Kahn, O. Pedersen, 1992, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Contraction-stimulated muscle glucose transport and GLUT-4 surface content are dependent on glycogen content.

W. Derave, J. Wojtaszewski, E. Richter, 1999, American journal of physiology. Endocrinology and metabolism.

Contraction-stimulated muscle glucose transport and GLUT-4 surface content are dependent on glycogen content.

W. Derave, J. Wojtaszewski, E. Richter, 1999, The American journal of physiology.

Study rationale and design of the CIMT trial: The Copenhagen Insulin and Metformin Therapy Trial

A. Vaag, L. Tarnow, H. Vestergaard, 2009, Diabetes, obesity & metabolism.

Expression of the major insulin regulatable glucose transporter (GLUT4) in skeletal muscle of noninsulin-dependent diabetic patients and healthy subjects before and after insulin infusion.

H. Vestergaard, B. Kahn, O. Pedersen, 1993, The Journal of clinical endocrinology and metabolism.

Decreased insulin binding to erythrocytes in subjects with Klinefelter's syndrome.

O. Pedersen, P. Cvitković, Z. Škrabalo, 1981, The Journal of clinical endocrinology and metabolism.

Beta-adrenergic regulation of prostaglandin E2 receptors in human and rat adipocytes.

O. Pedersen, B. Richelsen, 1985, Endocrinology.

Pancreatic endocrine function in recipients of segmental and whole pancreas transplantation.

J. Holst, O. Pedersen, N. Christensen, 1996, The Journal of clinical endocrinology and metabolism.

Insulin secretion, insulin action and non-insulin-dependent glucose uptake in pancreas transplant recipients.

O. Pedersen, N. Christensen, S. Madsbad, 1994, The Journal of clinical endocrinology and metabolism.

Kinetics of insulin binding and kinase activity of the partially purified insulin receptor from human skeletal muscle.

H. Beck-Nielsen, A. Handberg, O. Pedersen, 1990, Biochimica et biophysica acta.

Characterization of the insulin resistance of glucose utilization in adipocytes from patients with hyper- and hypothyroidism.

O. Pedersen, B. Richelsen, O. Schmitz, 1988, Acta Endocrinologica.

Comparative studies of insulin binding to receptor from adipocytes, hepatocytes, monocytes and erythrocytes from the pig. Similarities with insulin receptor binding in man.

O. Pedersen, B. Richelsen, E. Hjøllund, 1988, Acta endocrinologica.