K. Shirai

发表

Preheparin serum lipoprotein lipase mass might be a biomarker of metabolic syndrome.

A. Saiki, T. Oyama, K. Endo, 2007, Diabetes research and clinical practice.

Effect of exercise performed at anaerobic threshold on serum growth hormone and body fat distribution in obese patients with type 2 diabetes.

A. Saiki, K. Endo, Y. Miyashita, 2011, Obesity research & clinical practice.

Effect of combination therapy of benidipine hydrochloride and candesartan cilexetil on serum lipid metabolism and blood pressure in elderly hypertensive patients with type 2 diabetes mellitus.

T. Oyama, Y. Miyashita, K. Shirai, 2006, Journal of atherosclerosis and thrombosis.

Pioglitazone improves the cardio-ankle vascular index in patients with type 2 diabetes mellitus treated with metformin

I. Tatsuno, A. Saiki, M. Ohira, 2014, Diabetes, metabolic syndrome and obesity : targets and therapy.

Metformin promotes induction of lipoprotein lipase in skeletal muscle through activation of adenosine monophosphate-activated protein kinase.

M. Ohira, T. Murano, Y. Miyashita, 2009, Metabolism: clinical and experimental.

Effect of metformin on serum lipoprotein lipase mass levels and LDL particle size in type 2 diabetes mellitus patients.

A. Saiki, T. Oyama, K. Endo, 2007, Diabetes research and clinical practice.

Lipoprotein lipase-catalyzed hydrolysis of p-nitrophenyl butyrate. Interfacial activation by phospholipid vesicles.

K. Shirai, R. Jackson, Richard, 1982, The Journal of biological chemistry.

Beneficial effect of low carbohydrate in low calorie diets on visceral fat reduction in type 2 diabetic patients with obesity.

T. Oyama, N. Koide, Y. Miyashita, 2004, Diabetes research and clinical practice.

Trypsin treatment may impair the interfacial activation action of lipoprotein lipase.

Y. Morimoto, K. Shirai, J. Kobayashi, 1992, Journal of biochemistry.

Complications in adults with growth hormone deficiency--a survey study in Japan.

M. Irie, Y. Miyashita, K. Shirai, 2004, Endocrine journal.

Two cases with transient lipoprotein lipase (LPL) activity impairment: evidence for the possible involvement of an LPL inhibitor

H. Senzaki, T. Murano, K. Shirai, 2003, European Journal of Pediatrics.

Background characteristics and postoperative outcomes of insufficient weight loss after laparoscopic sleeve gastrectomy in Japanese patients

T. Kusakabe, Y. Seto, H. Matsubara, 2019, Annals of gastroenterological surgery.

Physiological role of nitric oxide for regulation of arterial stiffness in anesthetized rabbits.

Y. Nagasawa, K. Shirai, Mao Takahashi, 2019, Journal of pharmacological sciences.

Cardio‐ankle vascular index may reflect endothelial function in type 2 diabetes

A. Saiki, K. Endo, M. Ohira, 2011, International journal of clinical practice.

Protective effects of efonidipine, a T- and L-type calcium channel blocker, on renal function and arterial stiffness in type 2 diabetic patients with hypertension and nephropathy.

A. Saiki, T. Oyama, K. Endo, 2009, Journal of atherosclerosis and thrombosis.

Effects of olmesartan, an angiotensin II receptor blocker, and amlodipine, a calcium channel blocker, on Cardio-Ankle Vascular Index (CAVI) in type 2 diabetic patients with hypertension.

A. Saiki, T. Oyama, K. Endo, 2009, Journal of atherosclerosis and thrombosis.

Inhibition of intimal thickening of the carotid artery of rabbits and of outgrowth of explants of aorta by probucol.

M. Shinomiya, K. Shirai, Y. Saito, 1992, Atherosclerosis.

Changes in cardio-ankle vascular index in smoking cessation.

K. Shirai, Mao Takahashi, K. Shimizu, 2010, Journal of atherosclerosis and thrombosis.

Moderate oxidation of hypertriglyceridemic low-density lipoprotein causes apolipoprotein B epitope change and enhances its uptake by macrophages.

H. Inadera, K. Shirai, Y. Saito, 1992, Biochimica et biophysica acta.

Vascular smooth muscle cell apoptosis induced by 7-ketocholesterol was mediated via Ca2+ and inhibited by the calcium channel blocker nifedipine.

T. Murano, Y. Miyashita, K. Shirai, 2007, Metabolism: clinical and experimental.

Proliferation and triglyceride synthesizing activities of fibroblast-like cells derived from epididymal and subcutaneous adipose tissues of rats.

H. Inadera, K. Shirai, Y. Saito, 1993, Scandinavian journal of clinical and laboratory investigation.

Management of type IIb dyslipidemia.

S. Yamashita, H. Sone, H. Arai, 2012, Journal of atherosclerosis and thrombosis.

Relationship between two AMI risk factors: low serum lipoprotein lipase mass and hypoadiponectinemia.

K. Shirai, T. Hitsumoto, Mao Takahashi, 2011, Journal of atherosclerosis and thrombosis.

Efficacy and Safety of Lipase Inhibitor Orlistat in Japanese with Excessive Visceral Fat Accumulation: 24-Week, Double-Blind, Randomized, Placebo-Controlled Study

K. Shirai, S. Sakai, Toru Fujita, 2018, Advances in Therapy.

Reduction of Excessive Visceral Fat and Safety with 52-Week Administration of Lipase Inhibitor Orlistat in Japanese: Long-Term Clinical Study

K. Shirai, S. Sakai, Toru Fujita, 2018, Advances in Therapy.

Usefulness of preheparin lipoprotein lipase mass as a parameter for predicting the efficacy of colestimide.

T. Oyama, Y. Miyashita, K. Shirai, 2005, Journal of atherosclerosis and thrombosis.

High hemoglobin glycation index is associated with increased systemic arterial stiffness independent of hyperglycemia in real-world Japanese population: A cross-sectional study

I. Tatsuno, A. Saiki, K. Shirai, 2020, Diabetes & vascular disease research.

The role of polyol pathway in high glucose-induced endothelial cell damages.

T. Oyama, K. Shirai, Yoh Miyasita, 2006, Diabetes research and clinical practice.

Enhancement of serum lipoprotein lipase mass levels by intensive insulin therapy.

A. Saiki, T. Oyama, Mariko Ebisuno, 2006, Diabetes research and clinical practice.

Clinical efficacy of the direct assay method using polymers for serum high density lipoprotein cholesterol

Y. Miyashita, K. Shirai, Y. Itoh, 1997, Journal of clinical laboratory analysis.

Effect of High Density Lipoproteins Modified with Dilinoleoylphosphatidylcholine Vesicles on [3H]Cholesterol Release from Macrophages

K. Shirai, Yasushi Saito, S. Yoshida, 1987 .

Prognosis of hypercholesterolemic patients taking pravastatin for five years: the Chiba Lipid Intervention Program (CLIP) Study.

M. Shinomiya, K. Shirai, Yasushi Saito, 2002, Journal of atherosclerosis and thrombosis.

The Elevation of Cardio-Ankle Vascular Index in a Patient With Malignant Lymphoma Treated With a Combination Therapy of Rituximab and Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone

I. Tatsuno, A. Saiki, K. Shirai, 2017, Journal of Clinical Medicine Research.

The angiotensin II receptor antagonist valsartan enhances lipoprotein lipase mass in preheparin serum in type 2 diabetes with hypertension.

A. Saiki, T. Oyama, K. Endo, 2006, Diabetes research and clinical practice.

The effect of insulin sensitizer, troglitazone, on lipoprotein lipase mass in preheparin serum.

T. Murano, Y. Miyashita, K. Shirai, 1999, Diabetes research and clinical practice.

Slowß-migrating lipoprotein: An atherogenic subclass of low density lipoproteins

M. Shinomiya, K. Shirai, N. Morisaki, 1996 .

Chronic kidney disease, dyslipidemia, and atherosclerosis.

T. Abe, Y. Yamasaki, A. Kashiwagi, 2012, Journal of atherosclerosis and thrombosis.

Effects of phospholipids on hydrolysis of trioleoylglycerol by human serum carboxylesterase.

K. Shirai, Y. Saito, S. Yoshida, 1988, Biochimica et biophysica acta.

Probucol suppresses initiation of chronic hemodialysis therapy and renal dysfunction-related death in diabetic nephropathy patients: Sakura study.

I. Tatsuno, A. Saiki, T. Oyama, 2013, Journal of atherosclerosis and thrombosis.

Effect of weight loss using formula diet on renal function in obese patients with diabetic nephropathy

A. Saiki, T. Oyama, N. Koide, 2005, International Journal of Obesity.

Factors affecting high-sensitivity cardiac troponin T elevation in Japanese metabolic syndrome patients

K. Shirai, T. Hitsumoto, 2015, Diabetes, metabolic syndrome and obesity : targets and therapy.

CAVI-Lowering Effect of Pitavastatin May Be Involved in the Prevention of Cardiovascular Disease: Subgroup Analysis of the TOHO-LIP

M. Moroi, I. Tatsuno, A. Saiki, 2020, Journal of atherosclerosis and thrombosis.

Clearance rates of cerivastatin metabolites in a patient with cerivastatin‐induced rhabdomyolysis

T. Murano, Y. Miyashita, K. Shirai, 2005, Journal of clinical pharmacy and therapeutics.

Pitavastatin enhanced lipoprotein lipase expression in 3T3-L1 preadipocytes.

A. Saiki, T. Oyama, T. Murano, 2005, Journal of atherosclerosis and thrombosis.

Oxysterol-induced apoptosis of vascular smooth muscle cells is reduced by HMG-CoA reductase inhibitor, pravastatin.

T. Oyama, N. Koide, Y. Miyashita, 2002, Journal of atherosclerosis and thrombosis.

Metformin reduces circulating malondialdehyde-modified low-density lipoprotein in type 2 diabetes mellitus.

I. Tatsuno, A. Saiki, M. Ohira, 2014, Clinical and investigative medicine. Medecine clinique et experimentale.

Circulating angiotensin II is associated with body fat accumulation and insulin resistance in obese subjects with type 2 diabetes mellitus.

A. Saiki, T. Oyama, K. Endo, 2009, Metabolism: clinical and experimental.

Lecithinized superoxide dismutase treatment improves steroid‐refractory interstitial pneumonia

T. Nishide, K. Shirai, Y. Matsuzawa, 2010, Respirology.

Predictive ability of arterial stiffness parameters for renal function decline: a retrospective cohort study comparing cardio-ankle vascular index, pulse wave velocity and cardio-ankle vascular index0

A. Saiki, K. Shirai, S. Horinaka, 2022, Journal of hypertension.

[Evaluation of obesity and diagnostic criteria of obesity as a disease for Japanese].

K. Shirai, 2001, Nihon rinsho. Japanese journal of clinical medicine.

Effect of nicorandil administration on cardiac burden and cardio-ankle vascular index after coronary intervention

Shuji Sato, K. Shirai, Mao Takahashi, 2020, Heart and Vessels.

Should the Definition of Metabolic Syndrome be Reconsidered from the Aspect of Arterial Stiffness?

K. Shirai, 2022, Journal of atherosclerosis and thrombosis.

Effect of androgen deprivation therapy on arterial stiffness and serum lipid profile changes in patients with prostate cancer: a prospective study of initial 6-month follow-up

K. Shirai, Shuichi Kamijima, Hiroyoshi Suzuki, 2016, International Journal of Clinical Oncology.

Lipoprotein lipase: mechanism of action and role in lipoprotein metabolism.

K. Shirai, D. Quinn, R. Jackson, 1983, Progress in lipid research.

Estimating the extent of subclinical arteriosclerosis of persons with prediabetes and diabetes mellitus among Japanese urban workers and their families: a cross-sectional study

K. Shirai, Kenji Suzuki, N. Tanabe, 2016, BMC Cardiovascular Disorders.

Outcome of pitavastatin versus atorvastatin therapy in patients with hypercholesterolemia at high risk for atherosclerotic cardiovascular disease.

M. Moroi, K. Sugi, I. Tatsuno, 2020, International journal of cardiology.

Effects of Protein-Sparing Modified Fasting on Obese Japanese Patients

M. Shinomiya, K. Shirai, S. Yoshida, 1987 .

Atorvastatin and pitavastatin enhance lipoprotein lipase production in L6 skeletal muscle cells through activation of adenosine monophosphate-activated protein kinase.

I. Tatsuno, A. Saiki, K. Endo, 2012, Metabolism: clinical and experimental.

[Establishment and effect of the drug safety management monitoring system].

Y. Miyashita, K. Shirai, H. Sasaki, 2003, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Effect of acarbose, an alpha-glucosidase inhibitor, on serum lipoprotein lipase mass levels and common carotid artery intima-media thickness in type 2 diabetes mellitus treated by sulfonylurea.

A. Saiki, T. Oyama, N. Koide, 2008, Journal of atherosclerosis and thrombosis.

Effects of body weight reduction on cardio-ankle vascular index (CAVI).

A. Saiki, T. Oyama, K. Endo, 2013, Obesity research & clinical practice.

Opposing Responses of the Calcium Channel Blocker Nicardipine to Vascular Stiffness in the Elastic and Muscular Arteries in Rabbits

K. Shirai, A. Hazama, Tsuyoshi Shimizu, 2021, Journal of atherosclerosis and thrombosis.

A familial hyperalphalipoproteinemia with low uptake of high density lipoproteins into peripheral lymphocytes.

T. Nishide, M. Shinomiya, K. Shirai, 1988, Atherosclerosis.

Pseudohomozygous type II hyperlipoproteinemia.

K. Shirai, Y. Saito, M. Fujita, 1991, Dermatologica.

Frequency and role of apo E phenotype in familial hypercholesterolemia and non-familial hyperlipidemia in the Japanese.

M. Shinomiya, K. Shirai, M. Kitahara, 1990, Atherosclerosis.

A missense mutation (Trp 26-->Arg) in exon 3 of the apolipoprotein CII gene in a patient with apolipoprotein CII deficiency (apo CII-Wakayama).

H. Inadera, K. Shirai, J. Kobayashi, 1993, Biochemical and biophysical research communications.

Lipoprotein lipase mass and activity in severe hypertriglyceridemia.

K. Shirai, J. Kobayashi, Y. Saito, 1993, Clinica chimica acta; international journal of clinical chemistry.

The effects of partial use of formula diet on weight reduction and metabolic variables in obese type 2 diabetic patients--multicenter trial.

N. Sakane, N. Yamada, S. Ishibashi, 2013, Obesity research & clinical practice.

Sarpogrelate hydrochloride decreases cardio-ankle vascular index accompanied by increased serum lipoprotein lipase mass in type 2 diabetic patients.

I. Tatsuno, A. Saiki, M. Ohira, 2014, International heart journal.

An atherogenic midband lipoprotein: a risk factor for coronary artery disease in diabetes mellitus with hyperlipidemia.

M. Shinomiya, K. Shirai, N. Morisaki, 1998, Diabetes research and clinical practice.

The 'midband' lipoprotein is a coronary risk factor in Japanese patients with familial hypercholesterolaemia.

T. Nishide, H. Murayama, H. Ohshima, 1993, Scandinavian journal of clinical and laboratory investigation.

A case of adolescent hyperlipoproteinemia with xanthoma and acute pancreatitis, associated with decreased activities of lipoprotein lipase and hepatic triglyceride lipase.

S. Kihara, T. Funahashi, I. Shimomura, 2010, Internal medicine.

The effect of growth hormone secreted by mild exercise on fatty acid mobilization in patients with diabetes mellitus.

M. Irie, Y. Miyashita, K. Shirai, 1996, Endocrine journal.

Different Effect of Growth Hormone on the Triglyceride Metabolism in Visceral and Subcutaneous AdiposeTissues of Rats

M. Irie, Y. Miyashita, K. Shirai, 1996 .

Hydrolysis of human plasma high density lipoprotein 2- phospholipids and triglycerides by hepatic lipase.

K. Shirai, R. Jackson, R. L. Barnhart, 1981, Biochemical and biophysical research communications.

Lipoprotein lipase catalyzed hydrolysis of water-soluble p-nitrophenyl esters. Inhibition by apolipoprotein C-II.

K. Shirai, D. Quinn, R. Jackson, 1982, Biochemistry.

Positive correlation between probucol in low density lipoprotein and LDL-lowering

M. Shinomiya, K. Shirai, Y. Saito, 2004, European Journal of Clinical Pharmacology.

Regulation of neutral cholesterol esterase activity by phospholipids containing negative charges in substrate liposome.

K. Shirai, N. Fujio, N. Morisaki, 1995, Journal of lipid research.

Lipoprotein lipase- and phospholipase A2-catalyzed hydrolysis of phospholipid vesicles with an encapsulated fluorescent dye. Effects of apolipoproteins.

J. Johnson, K. Shirai, R. Jackson, 1984, Biochimica et biophysica acta.

Impact of monocyte colony-stimulating factor upon beta-very low density lipoprotein (beta-VLDL) cholesterol metabolism in tetradecanoyl phorbol acetate-derived THP-1 cells.

K. Shirai, Y. Saito, I. Ishii, 1994, Biochimica et biophysica acta.

Effect of pantethine on cholesterol ester metabolism in rat arterial wall.

M. Shinomiya, K. Shirai, N. Morisaki, 1980, Atherosclerosis.

Lipids deposited in human atheromatous lesions induce apoptosis of human vascular smooth muscle cells.

Y. Miyashita, K. Shirai, M. Ohtsuka, 2006, Journal of atherosclerosis and thrombosis.

Prevention of Cardiovascular Events with Pitavastatin is Associated with Increased Serum Lipoprotein Lipase Mass Level: Subgroup Analysis of the TOHO-LIP

M. Moroi, I. Tatsuno, A. Saiki, 2021, Journal of atherosclerosis and thrombosis.

VHRM_A_306540 169..173

A. Saiki, K. Shirai, D. Nagayama, 2021 .

The Anti-Cancer Effect of Pitavastatin May Be a Drug-Specific Effect: Subgroup Analysis of the TOHO-LIP Study

A. Saiki, K. Shirai, D. Nagayama, 2021, Vascular health and risk management.

Effect of conditioning of β-migrating very low-density lipoprotein with macrophages on the accumulation of cholesteryl esters in smooth muscle cells

T. Nishide, K. Shirai, N. Morisaki, 1992 .

Pioglitazone decreases plasma angiotensin II concentration in type 2 diabetes.

A. Saiki, T. Oyama, K. Endo, 2010, Journal of atherosclerosis and thrombosis.

Low lipoprotein lipase mass in preheparin serum of type 2 diabetes mellitus patients and its recovery with insulin therapy.

T. Murano, Y. Miyashita, K. Shirai, 2002, Diabetes research and clinical practice.

Lipoprotein lipase-catalyzed hydrolysis of tri[14C]oleoylglycerol in a phospholipid interface. A monolayer study.

K. Shirai, R. Demel, R. Jackson, 1982, Biochimica et biophysica acta.

Are you as old as your arteries? Comparing arterial aging in Japanese and European patient groups using cardio-ankle vascular index

I. Tatsuno, K. Shirai, J. Cruickshank, 2022, Journal of hypertension.

Effect of niceritrol on lipid metabolism of aorta in atherosclerotic rats.

T. Nishide, K. Shirai, Y. Saito, 1984, The Tohoku journal of experimental medicine.

Proliferation and LDL binding of cultured intimal smooth muscle cells from rabbits.

K. Shirai, N. Morisaki, H. Bujo, 1988, Atherosclerosis.

A case of obstructive jaundice with severe hypercholesterolemia probably due to lipoprotein-Y.

T. Oyama, T. Murano, Y. Miyashita, 2008, Journal of atherosclerosis and thrombosis.

How should adequate serum cholesterol level be set

K. Shirai, 2005 .

Suppression of lipoprotein lipase expression in 3T3-L1 cells by inhibition of adipogenic differentiation through activation of the renin-angiotensin system.

A. Saiki, N. Koide, T. Murano, 2008, Metabolism: clinical and experimental.

Effects of chloroquine on the metabolism of phosphatidylcholine associated with low density lipoprotein in arterial smooth muscle cells.

T. Nishide, K. Shirai, Y. Saito, 1989, Atherosclerosis.

Various Obesity Indices and Arterial Function Evaluated with CAVI – Is Waist Circumference Adequate to Define Metabolic Syndrome?

K. Shirai, Su-Yeon Choi, D. Nagayama, 2022, Vascular health and risk management.

Catabolism of lipoprotein-X induced by infusion of 10% fat emulsion.

K. Shirai, H. Yamamori, T. Tashiro, 1997, Nutrition.

Effect of nifedipine administration on pulse wave velocity (PWV) of chronic hemodialysis patients—2-year trial

K. Shirai, J. Uchino, S. Yoshida, 1990, Cardiovascular Drugs and Therapy.

Characteristic Features of Long‐Living Patients with Familial Hypercholesterolemia in Japan

M. Shinomiya, K. Shirai, Y. Saito, 1993, Journal of the American Geriatrics Society.

Effects of Long‐Term Treatment with Probucol on Serum Lipoproteins in Cases of Familial Hypercholesterolemia in the Elderly

M. Shinomiya, K. Shirai, J. Kobayashi, 1990, Journal of the American Geriatrics Society.

Lipoprotein lipase with a defect in lipid interface recognition in a case with type I hyperlipidaemia

K. Shirai, J. Kobayashi, Y. Saito, 1989, European journal of clinical investigation.

Dyslipoproteinemia and an inhibitor of lipolytic enzymes in Weber-Christian disease.

K. Shirai, Y. Saito, N. Matsuoka, 1989, Japanese journal of medicine.

Impaired intermediate-density lipoprotein triglyceride hydrolysis in familial lecithin:cholesterol acyltransferase (LCAT) deficiency.

G. Asano, K. Shirai, J. Albers, 1987, Scandinavian journal of clinical and laboratory investigation.

Lipid metabolism in arteriosclerotic arterial wall of rats.

M. Shinomiya, K. Shirai, N. Morisaki, 1982, Atherosclerosis.

Effect of tocopherol deficiency on lipid metabolism in arterial wall of spontaneously hypertensive rats on normal and high cholesterol diets.

M. Shinomiya, K. Shirai, N. Morisaki, 1982, The Tohoku journal of experimental medicine.

A heterozygous mutation (the codon for Ser447----a stop codon) in lipoprotein lipase contributes to a defect in lipid interface recognition in a case with type I hyperlipidemia.

K. Shirai, J. Kobayashi, M. Schotz, 1992, Biochemical and biophysical research communications.

Arterial stiffness, as monitored by cardio–ankle vascular index, is affected by obstructive sleep apnea, blood glucose control, and body weight – a case with 8 years follow up

K. Shirai, K. Shimizu, Tomoyuki Yamamoto, 2016, International medical case reports journal.

Phosphate overload accelerates vascular calcium deposition in end-stage renal disease patients.

T. Shigematsu, K. Shirai, T. Hosoya, 2003, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Comparison of Predictive Ability of Arterial Stiffness Parameters Including Cardio-Ankle Vascular Index, Pulse Wave Velocity and Cardio-Ankle Vascular Index0

K. Shirai, K. Fujishiro, D. Nagayama, 2022, Vascular health and risk management.

VHRM_A_378292 735..745

K. Shirai, K. Fujishiro, D. Nagayama, 2022 .

Preparation and properties of immobilized lipoprotein lipase.

K. Shirai, R. Jackson, N. Matsuoka, 1980, Biochimica et biophysica acta.

Hydrolysis of cholesterol ester in artificial lipid mixtures by cholesterol esterase released from particulate fractions of rat arterial wall.

M. Shinomiya, K. Shirai, Y. Saito, 1984, The Tohoku journal of experimental medicine.

Ideal body mass index determined by mortality in Europe, and adequate high protein and low carbohydrate diet to maintain bodyweight

K. Shirai, 2011, Journal of diabetes investigation.

Characteristics of Childhood Onset and Post-Puberty Onset Obesity and Weight Regain after Laparoscopic Sleeve Gastrectomy in Japanese Subjects: A Subgroup Analysis of J-SMART

H. Matsubara, I. Tatsuno, K. Yokote, 2022, Obesity Facts.

Effect of deposited lipids in atheromatous lesions on the migration of vascular smooth muscle cells.

T. Oyama, Y. Miyashita, K. Shirai, 2000, Journal of atherosclerosis and thrombosis.

Catabolism of human very low density lipoproteins in vitro: a fluorescent phospholipid method for monitoring lipolysis.

M. Taskinen, C. Glueck, J. Johnson, 1981, Journal of lipid research.

The recovery of dysfunctional lipoprotein lipase (Asp204-Glu) activity by modification of substrate.

T. Murano, K. Shirai, S. Oikawa, 2005, Atherosclerosis.

Hydrolysis of a fluorescent phospholipid substrate by phospholipase A2 and lipoprotein lipase.

J. Johnson, K. Shirai, R. Jackson, 1984, Biochemical and biophysical research communications.

Effect of rosuvastatin 5-20mg on triglycerides and other lipid parameters in Japanese patients with hypertriglyceridemia.

T. Yanase, J. Sasaki, N. Yamada, 2007, Atherosclerosis.

Insulin Degludec improves Blood Glucose but Does Not Alter Arterial Stiffness in Type 1 Diabetes Patients

I. Tatsuno, A. Saiki, K. Endo, 2016 .

Lipoprotein lipase-catalyzed hydrolysis of phosphatidylcholine of guinea pig very low density lipoproteins and discoidal complexes of phospholipid and apolipoprotein: effect of apolipoprotein C-II on the catalytic mechanism.

M. Shinomiya, H. Muntz, K. Shirai, 1983, Journal of lipid research.

Interaction of lipoprotein lipase with phospholipid vesicles. Role of apolipoprotein C-II and heparin.

K. Shirai, R. Jackson, N. Matsuoka, 1981, Biochimica et biophysica acta.

Immunological studies on bovine milk lipoprotein lipase. Effects of Fab fragments on enzyme activity.

J. Johnson, K. Shirai, R. Jackson, 1982, Biochimica et biophysica acta.

Effects of apolipoprotein C-II (apoC-II) on the lipolysis of very low density lipoproteins from apoC-II deficient patients.

J. Johnson, K. Shirai, R. Jackson, 1981, Metabolism: clinical and experimental.

Effect of glycyrrhizin on lysis of hepatocyte membranes induced by anti‐liver cell membrane antibody

K. Shirai, S. Yoshida, Y. Saito, 1992, Journal of gastroenterology and hepatology.

DEHYDRATION ENCEPHALOPATHY: A NEUROLOGICAL EMERGENCY IN THE OLDER ADULTS

R. Sakakibara, K. Shirai, Y. Matsuzawa, 2010, Journal of the American Geriatrics Society.

The Effect of on Fatty Acid Growth Hormone Secreted by Mobilization in Patients with Mild Exercise Diabetes Mellitus

M. Irie, Y. Miyashita, K. Shirai, 2006 .

Correlations between the Serum Apolipoprotein A-I, A-II, B, C-II, C-III, and E Levels and Cholinesterase in Various Hyperlipidemias

K. Shirai, S. Yoshida, H. Yonemitsu, 1991 .

Effect of phospholipids on lipase activity in rat arterial wall homogenate.

K. Shirai, Y. Saito, A. Kumagai, 1982, The Tohoku journal of experimental medicine.

Existence of lipoprotein lipase in rat brain microvessels.

K. Shirai, Y. Saito, S. Yoshida, 1986, The Tohoku journal of experimental medicine.

The Mode of Lipid-lowering Drugs: -Vitamin Derivatives-@@@―ビタミン類―

K. Shirai, Y. Saito, 1985 .

Multiple system atrophy and impaired gallbladder emptying

R. Sakakibara, T. Oyama, K. Shirai, 2008, Movement disorders : official journal of the Movement Disorder Society.

Occult Hepatitis B Virus Infection in Japanese Chronic Hemodialysis Patients

K. Shirai, M. Masai, Emi Inayama, 2013, Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.

Further Role of Blood Pressure-Independent CAVI in Addition to a Predictor of Cardiovascular Events

K. Shirai, 2020, Journal of atherosclerosis and thrombosis.

Cardio-Ankle Vascular Index Reflects the Efficacy of Waon Therapy in Heart Failure Patients.

T. Akiba, K. Shirai, K. Shimizu, 2022, International heart journal.

Human plasma carboxyl esterase-catalyzed triolein hydrolysis. Existence of promoting factor in serum.

K. Shirai, Y. Saito, S. Yoshida, 1985, The Journal of biological chemistry.

Post-heparin plasma hepatic triacylglycerol lipase-catalyzed tributyrin hydrolysis. Effect of trypsin treatment.

K. Shirai, Y. Saito, S. Yoshida, 1984, Biochimica et biophysica acta.

A novel blood pressure-independent arterial wall stiffness parameter; cardio-ankle vascular index (CAVI).

Kuniaki Otsuka, K. Otsuka, K. Shirai, 2006, Journal of atherosclerosis and thrombosis.

Regulation of lipase activities in rat brain in vitro.

K. Shirai, Y. Saito, A. Kumagai, 1981, The Tohoku journal of experimental medicine.

Studies on Lipase in Rat Brain

K. Shirai, A. Kumagai, N. Matsuoka, 1981, Journal of neurochemistry.

Obesity as the core of the metabolic syndrome and the management of coronary heart disease

K. Shirai, 2004, Current medical research and opinion.

Delayed Triglyceride Clearance from Blood in Aged Rats

T. Nishide, K. Shirai, S. Yoshida, 1988 .

Endocrine disorders and body fat distribution.

M. Shinomiya, H. Inadera, K. Shirai, 1991, International journal of obesity.

Optic nerve head circulation determined by pulse wave analysis is significantly correlated with cardio ankle vascular index, left ventricular diastolic function, and age.

K. Shirai, T. Maeno, T. Shiba, 2012, Journal of atherosclerosis and thrombosis.

Abnormal metabolism of polyunsaturated fatty acids and phospholipids in diabetic glomeruli

K. Shirai, N. Morisaki, S. Yoshida, 1987, Lipids.

Role of lipoprotein lipase separated from VLDL during VLDL catabolism.

K. Shirai, Y. Saito, A. Kumagai, 1982, Biochemical and biophysical research communications.

Studies on cholesterol esterase in cultured rabbit smooth muscle cells.

T. Nishide, K. Shirai, Y. Saito, 1985, The Tohoku journal of experimental medicine.

Studies of cholesterol esterase in rat arterial wall.

M. Shinomiya, K. Shirai, Y. Saito, 1979, Atherosclerosis.

Studies on CDP-choline:1,2-diacylglycerol cholinephosphotransferase activity in rat arterial wall.

K. Shirai, Y. Saito, N. Sasaki, 1982, Atherosclerosis.

Multiple system atrophy and the syndrome of inappropriate secretion of antidiuretic hormone

R. Sakakibara, K. Endo, K. Shirai, 2008, Movement disorders : official journal of the Movement Disorder Society.

Relationship between lipase and esterase.

T. Tsujita, K. Shirai, H. Okuda, 1968, Progress in clinical and biological research.

Hepatocyte growth factor secreted by cultured adipocytes promotes tube formation of vascular endothelial cells in vitro

A. Saiki, T. Murano, Y. Miyashita, 2006, International Journal of Obesity.

Cardio-ankle vascular index is a candidate predictor of coronary atherosclerosis.

Takanobu Tomaru, Y. Miyashita, K. Shirai, 2008, Circulation journal : official journal of the Japanese Circulation Society.

Cardio-ankle vascular index in heterozygous familial hypercholesterolemia.

T. Yambe, L. Dušek, M. Nováková, 2012, Journal of atherosclerosis and thrombosis.

Low Leptin Level Might Increase Susceptibility to Mycobacterium Avium Complex Infection

K. Shirai, Y. Matsuzawa, T. Kawashima, 2016 .

Increased cardio-ankle vascular index in hyperlipidemic patients without diabetes or hypertension.

M. Nováková, F. Lopez‐Jimenez, O. Sochor, 2015, Journal of atherosclerosis and thrombosis.

Cardio-Ankle Vascular Index is Associated with Prevalence and New-Appearance of Atrial Fibrillation in Japanese Urban Residents: A Retrospective Cross-Sectional and Cohort Study

A. Saiki, K. Shirai, K. Shimizu, 2022, Vascular health and risk management.

Issue of Waist Circumference for the Diagnosis of Metabolic Syndrome Regarding Arterial Stiffness: Possible Utility of a Body Shape Index in Middle-Aged Nonobese Japanese Urban Residents Receiving Health Screening

A. Saiki, K. Shirai, Kenji Suzuki, 2022, Obesity Facts.

VHRM_A_351602 5..15

A. Saiki, K. Shirai, K. Shimizu, 2022 .

The Role of Cardio-Ankle Vascular Index as a Predictor of Mortality in Patients on Maintenance Hemodialysis

Masashi Iwasaki, K. Shirai, M. Masai, 2021, Vascular Health and Risk Management.

Relation of Maximum Lifetime Body Mass Index with Age at Hemodialysis Initiation and Vascular Complications in Japan

I. Tatsuno, K. Shirai, M. Masai, 2021, Obesity Facts.

VHRM_A_339769 791..798

Masashi Iwasaki, K. Shirai, M. Masai, 2021 .

Lipid Parameters are Independently Associated with Cardio–Ankle Vascular Index (CAVI) in Healthy Japanese Subjects

I. Tatsuno, A. Saiki, K. Shirai, 2018, Journal of atherosclerosis and thrombosis.

A frameshift variant of CYP2C8 was identified in a patient who suffered from rhabdomyolysis after administration of cerivastatin

Ituro Inoue, Hiroshi Ozaki, Saburo Kanai, 2004, Journal of Human Genetics.

Angiotensin II acutely increases arterial stiffness as monitored by cardio-ankle vascular index (CAVI) in anesthetized rabbits.

Y. Nagasawa, K. Shirai, Y. Hori, 2019, Journal of pharmacological sciences.

[Hypertriglyceridemia-induced pancreatitis].

K. Shirai, D. Nagayama, 2013, Nihon rinsho. Japanese journal of clinical medicine.

Type I hyperlipoproteinemia caused by lipoprotein lipase defect in lipid-interface recognition was relieved by administration of medium-chain triglyceride.

H. Inadera, K. Shirai, J. Kobayashi, 1992, Metabolism: clinical and experimental.

Aseptic meningitis as the sole manifestation of Behçet’s disease

R. Sakakibara, N. Koide, K. Shirai, 2009, Neurological Sciences.

Cardio-ankle vascular index relates to left ventricular ejection fraction in patients with heart failure. A retrospective study.

Hongyu Wang, A. Saiki, T. Oyama, 2013, International heart journal.

[HMG-CoA reductase].

K. Shirai, H. Ozaki, 2001, Nihon rinsho. Japanese journal of clinical medicine.

Effects of bezafibrate on lipid and glucose metabolism in dyslipidemic patients with diabetes: the J-BENEFIT study

H. Daida, N. Yamada, K. Shirai, 2012, Cardiovascular Diabetology.

Effects of pitavastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, on cardio-ankle vascular index in type 2 diabetic patients.

A. Saiki, T. Oyama, K. Endo, 2009, Journal of atherosclerosis and thrombosis.

Apoptosis induced by 7-ketocholesterol is enhanced in smooth muscle cells derived from OLETF rats.

T. Oyama, N. Koide, Y. Miyashita, 2005, Journal of atherosclerosis and thrombosis.

[Relationship between insulin resistance and oxidative stress in vivo].

K. Shirai, T. Hitsumoto, Mao Takahashi, 2003, Journal of cardiology.

Formula diet is effective for the reduction and differentiation of visceral adipose tissue in Zucker fatty rats.

A. Saiki, Y. Miyashita, K. Shirai, 2012, Journal of atherosclerosis and thrombosis.

A Body Shape Index (ABSI) as a Variant of Conicity Index Not Affected by the Obesity Paradox: A Cross-Sectional Study Using Arterial Stiffness Parameter

A. Saiki, K. Shirai, K. Fujishiro, 2022, Journal of personalized medicine.

Enhanced prediction of renal function decline by replacing waist circumference with “A Body Shape Index (ABSI)” in diagnosing metabolic syndrome: a retrospective cohort study in Japan

A. Saiki, K. Shirai, Kenji Suzuki, 2021, International Journal of Obesity.

New index of abdominal obesity, a body shape index, is BMI-independently associated with systemic arterial stiffness in real-world Japanese population .

I. Tatsuno, A. Saiki, K. Shirai, 2020, International journal of clinical pharmacology and therapeutics.

New Horizons of Arterial Stiffness Developed Using Cardio-Ankle Vascular Index (CAVI)

I. Tatsuno, A. Saiki, M. Ohira, 2020, Journal of atherosclerosis and thrombosis.

Impaired consciousness caused by a metastatic adrenal tumor of pulmonary adenocarcinoma.

K. Shirai, Y. Matsuzawa, T. Kawashima, 2008, Internal medicine.

Physical Function and Cardio-Ankle Vascular Index in Elderly Heart Failure Patients.

K. Shirai, K. Shimizu, H. Maruoka, 2020, International heart journal.

Incidence of childhood obesity over the last 10 years in Japan.

M. Shinomiya, K. Shirai, Y. Saito, 1990, Diabetes research and clinical practice.

Difference in positive relation between cardio-ankle vascular index (CAVI) and each of four blood pressure indices in real-world Japanese population

I. Tatsuno, A. Saiki, K. Shirai, 2019, Journal of Human Hypertension.

Effect of the angiotensin II receptor antagonist telmisartan on lipoprotein lipase mass in preheparin serum.

K. Shirai, T. Hitsumoto, Mao Takahashi, 2008, Journal of atherosclerosis and thrombosis.

Dose-dependent effect of niceritrol on plasma lipoprotein-a.

H. Shimano, M. Kawakami, K. Shirai, 1996, Scandinavian journal of clinical and laboratory investigation.

Effect of 5-year administration of probucol on development of myocardial infarction in heterozygous familial hypercholesterolemia

T. Nishide, M. Shinomiya, K. Shirai, 1993 .

Establishing baseline criteria of cardio-ankle vascular index as a new indicator of arteriosclerosis: a cross-sectional study

K. Shirai, Kenji Suzuki, T. Namekata, 2011, BMC cardiovascular disorders.

Enhancement of MMP-9 activity in THP-1 cells by 7-ketocholesterol and its suppression by the HMG-CoA reductase inhibitor fluvastatin.

Y. Miyashita, K. Shirai, H. Ozaki, 2005, Journal of atherosclerosis and thrombosis.

Atorvastatin and pravastatin elevated pre-heparin lipoprotein lipase mass of type 2 diabetes with hypercholesterolemia.

A. Saiki, T. Oyama, K. Endo, 2004, Journal of atherosclerosis and thrombosis.

Arterial stiffness shown by the cardio-ankle vascular index is an important contributor to optic nerve head microcirculation

K. Shirai, T. Shiba, Mao Takahashi, 2016, Graefe's Archive for Clinical and Experimental Ophthalmology.

The Role of Monitoring Arterial Stiffness with Cardio-Ankle Vascular Index in the Control of Lifestyle-Related Diseases

I. Tatsuno, A. Saiki, K. Shirai, 2015, Pulse.

Association between cardio-ankle vascular index and serum cystatin C levels in patients with cardiovascular risk factor.

Y. Miyashita, K. Shirai, T. Tomaru, 2009, Journal of atherosclerosis and thrombosis.

Marker Of Sepsis Severity Is Associated With The Variation In Cardio-Ankle Vascular Index (CAVI) During Sepsis Treatment

I. Tatsuno, A. Saiki, K. Endo, 2019, Vascular health and risk management.

VHRM_A_228506 509..516

I. Tatsuno, A. Saiki, K. Endo, 2019 .

Importance of Isolated Anti‐HBc in Detection of Occult Hepatitis B Virus Infection in Hemodialysis Patients: Reply

Predictive Value of the Cardio‐Ankle Vascular Index for Cardiovascular Events in Patients at Cardiovascular Risk

J. Higaki, K. Kotani, H. Yagi, 2021, Journal of the American Heart Association.

Current and future initiatives for vascular health management in clinical practice

R. Asmar, J. Topouchian, K. Shirai, 2013, Vascular health and risk management.

Cardio-ankle vascular index (CAVI) differentiates pharmacological properties of vasodilators nicardipine and nitroglycerin in anesthetized rabbits.

K. Shirai, Mao Takahashi, K. Shimizu, 2015, Journal of pharmacological sciences.

Changes in blood pressure and arterial stiffness monitored using the cardio–ankle vascular index during hemodialysis

Shuji Sato, K. Shirai, Mao Takahashi, 2023, Frontiers in Physiology.

The Background of Calculating CAVI: Lesson from the Discrepancy Between CAVI and CAVI0

K. Shirai, M. Maruyama, Tomoyuki Yamamoto, 2020, Vascular health and risk management.

Coefficients in the CAVI Equation and the Comparison Between CAVI With and Without the Coefficients Using Clinical Data

K. Otsuka, K. Shirai, K. Shimizu, 2019, Journal of atherosclerosis and thrombosis.

Clinical assessment of arterial stiffness with cardio-ankle vascular index: theory and applications.

Akira Takahara, K. Shirai, Kozaburo Hayashi, 2015, Journal of hypertension.

A Comparative Study of the Therapeutic Effect of Probucol and Pravastatin on Xanthelasma

K. Shirai, M. Fujita, K. Shirai, 1996, The Journal of dermatology.

The Effect of Nitroglycerin on Arterial Stiffness of the Aorta and the Femoral-Tibial Arteries

I. Tatsuno, K. Shirai, Mao Takahashi, 2017, Journal of atherosclerosis and thrombosis.

Send Orders of Reprints at Reprints@benthamscience.net Evaluation of Blood Pressure Control Using a New Arterial Stiffness Parameter, Cardio-ankle Vascular Index (cavi)

I. Tatsuno, A. Saiki, K. Endo, 2022 .

Clinical significance of serum 7-ketocholesterol concentrations in the progression of coronary atherosclerosis.

K. Shirai, T. Hitsumoto, Mao Takahashi, 2009, Journal of atherosclerosis and thrombosis.

Frequency of coronary artery stenosis in patients with asymptomatic familial hypercholesterolemia and its association with carotid intimal thickness and cardio-ankle vascular index [Corrigendum]

K. Shirai, Mao Takahashi, H. Noike, 2016 .

Cardio-ankle vascular index elevation in patients with exudative age-related macular degeneration.

K. Shirai, T. Maeno, T. Shiba, 2013, Journal of atherosclerosis and thrombosis.

Association between preheparin serum lipoprotein lipase mass and acute myocardial infarction in Japanese men.

K. Shirai, T. Hitsumoto, T. Sakurai, 2002, Journal of atherosclerosis and thrombosis.

Relationship between metabolic syndrome and early stage coronary atherosclerosis.

K. Shirai, T. Hitsumoto, Mao Takahashi, 2007, Journal of atherosclerosis and thrombosis.

Reciprocal effect of apolipoprotein C-II on the lipoprotein lipase-catalyzed hydrolysis of p-nitrophenyl butyrate and trioleoylglycerol.

K. Shirai, D. Quinn, R. Jackson, 1982, The Journal of biological chemistry.

Response of lipoprotein lipase to calorie intake in streptozotocin-induced diabetic rats.

H. Inadera, K. Shirai, Y. Saito, 1992, Scandinavian journal of clinical and laboratory investigation.

Effects of treatment with bezafibrate on lipoprotein lipase activity and mass in patients with hypertriglyceridemia.

K. Shirai, J. Kobayashi, Y. Saito, 1994, Arzneimittel-Forschung.

Effects of pantetheine on cholesteryl ester synthesis in the arterial wall of rats on high cholesterol diet.

K. Shirai, H. Okuda, Y. Saito, 1979, The Tohoku journal of experimental medicine.

Cardio-ankle vascular index (CAVI) as a novel indicator of arterial stiffness: theory, evidence and perspectives.

Takanobu Tomaru, Y. Miyashita, K. Shirai, 2011, Journal of atherosclerosis and thrombosis.

Background to discuss guidelines for control of plasma HDL-cholesterol in Japan.

S. Yamashita, H. Sone, H. Arai, 2012, Journal of atherosclerosis and thrombosis.

Presence and properties of acyl coenzyme A synthetase for medium-chain fatty acids in rat intestinal mucosa.

K. Shirai, Y. Saito, S. Mori, 1992, Digestion.

Factors Associated with Relapse of Type 2 Diabetes Mellitus after Laparoscopic Sleeve Gastrectomy in Japanese Subjects: A Subgroup Analysis of J-SMART Study

H. Matsubara, I. Tatsuno, K. Yokote, 2023, Obesity Facts.

Background characteristics and diabetes remission after laparoscopic sleeve gastrectomy in Japanese patients with type 2 diabetes stratified by BMI: subgroup analysis of J-SMART

H. Matsubara, M. Ohta, I. Tatsuno, 2021, Diabetology International.

Cardio-Ankle Vascular Index is Independently Associated with Future Cardiovascular Events in Outpatients with Metabolic Disorders.

I. Tatsuno, A. Saiki, K. Endo, 2016, Journal of atherosclerosis and thrombosis.

Bezafibrate Ameliorates Arterial Stiffness Assessed by Cardio-Ankle Vascular Index in Hypertriglyceridemic Patients with Type 2 Diabetes Mellitus

I. Tatsuno, A. Saiki, M. Ohira, 2019, Journal of atherosclerosis and thrombosis.

1P-0251 Apoptosis of smooth muscle cells induced by oxysterol was enhanced under diabetic condition

A. Saiki, T. Oyama, N. Koide, 2003 .

Rapid Rise of Cardio-Ankle Vascular Index May Be a Trigger of Cerebro-Cardiovascular Events: Proposal of Smooth Muscle Cell Contraction Theory for Plaque Rupture

C. Miyazaki, M. Harada, Shuji Sato, 2021, Vascular health and risk management.

Analysis of vascular function using the cardio–ankle vascular index (CAVI)

K. Shirai, 2011, Hypertension Research.

Different Responses of Arterial Stiffness between the Aorta and the Iliofemoral Artery during the Administration of Phentolamine and Atenolol in Rabbits

K. Shirai, A. Hazama, Tsuyoshi Shimizu, 2020, Journal of atherosclerosis and thrombosis.

Cardio-ankle vascular index in subjects with dyslipidaemia and other cardiovascular risk factors.

L. Dušek, M. Nováková, L. Fajkusová, 2013, Journal of atherosclerosis and thrombosis.

Stroke and cardio-ankle vascular stiffness index.

R. Sakakibara, K. Shirai, T. Tomaru, 2013, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

Effects of serotonin on expression of the LDL receptor family member LR11 and 7-ketocholesterol-induced apoptosis in human vascular smooth muscle cells.

I. Tatsuno, K. Shirai, H. Bujo, 2014, Biochemical and biophysical research communications.

Interaction of endothelial cells and triglyceride-rich lipoproteins with apolipoprotein E (Arg-->Cys) from a patient with lipoprotein glomerulopathy.

T. Sugiyama, T. Murano, Y. Miyashita, 2002, Metabolism: clinical and experimental.

Effect of Mazindol on Monosodium Glutamate-Induced Obesity in Rats

T. Nishide, K. Shirai, S. Yoshida, 1987 .

Prevalence and mechanism of bladder dysfunction in Guillain–Barré Syndrome

R. Sakakibara, N. Yuki, K. Shirai, 2009, Neurourology and urodynamics.

Protocol for Evaluating the Cardio-Ankle Vascular Index to Predict Cardiovascular Events in Japan: A Prospective Multicenter Cohort Study

J. Higaki, K. Shirai, S. Horinaka, 2016, Pulse.

Effect of nitroglycerin administration on cardio-ankle vascular index

Shuji Sato, K. Shirai, Mao Takahashi, 2016, Vascular health and risk management.

A huge earthquake hardened arterial stiffness monitored with cardio-ankle vascular index.

K. Shirai, Mao Takahashi, K. Shimizu, 2013, Journal of atherosclerosis and thrombosis.

Evaluation of Arteriosclerotic Vascular Disease with a New Noble Stiffness Indicator, Cardio-Ankle Vascular Index (CAVI)

I. Tatsuno, A. Saiki, K. Shirai, 2012 .

Acute decrease of cardio-ankle vascular index with the administration of beraprost sodium.

K. Shirai, T. Hitsumoto, T. Shiba, 2012, Journal of atherosclerosis and thrombosis.

Contradictory effects of β1- and α1- aderenergic receptor blockers on cardio-ankle vascular stiffness index (CAVI)--CAVI independent of blood pressure.

T. Oyama, Y. Miyashita, K. Shirai, 2011, Journal of atherosclerosis and thrombosis.

Resveratrol attenuates triglyceride accumulation associated with upregulation of Sirt1 and lipoprotein lipase in 3T3-L1 adipocytes

I. Tatsuno, A. Saiki, K. Endo, 2017, Molecular genetics and metabolism reports.

Isolated facio-lingual hypoalgesia and weakness after a hemorrhagic infarct localized at the contralateral operculum

R. Sakakibara, K. Shirai, M. Kishi, 2009, Journal of the Neurological Sciences.

Resveratrol Ameliorates Arterial Stiffness Assessed by Cardio-Ankle Vascular Index in Patients With Type 2 Diabetes Mellitus.

I. Tatsuno, A. Saiki, K. Shirai, 2017, International heart journal.

Inverse relationship of cardioankle vascular index with BMI in healthy Japanese subjects: a cross-sectional study

I. Tatsuno, A. Saiki, M. Ohira, 2016, Vascular health and risk management.

High serum uric acid is associated with increased cardio-ankle vascular index (CAVI) in healthy Japanese subjects: a cross-sectional study.

I. Tatsuno, A. Saiki, K. Shirai, 2015, Atherosclerosis.

Effect of pantethine on fatty acid oxidation in microvessels of rat brain.

K. Shirai, N. Morisaki, Y. Saito, 1983, The Tohoku journal of experimental medicine.

Comparison of Cardio-Ankle Vascular Index (CAVI) and CAVI0 in Large Healthy and Hypertensive Populations

K. Shirai, K. Shimizu, Kenji Suzuki, 2019, Journal of atherosclerosis and thrombosis.

Effects of Enhanced Intracranial Pressure on Blood Pressure and the Cardio-Ankle Vascular Index in Rabbits

C. Miyazaki, N. Sugo, Y. Nagasawa, 2021, Journal of atherosclerosis and thrombosis.

Change in serum marker of oxidative stress in the progression of idiopathic pulmonary fibrosis.

K. Shirai, Yasuo Suzuki, Y. Matsuzawa, 2015, Pulmonary pharmacology & therapeutics.

The level of pre-heparin serum lipoprotein lipase mass at different stages of pregnancy.

K. Shirai, T. Kinoshita, M. Itoh, 2003, Clinica chimica acta; international journal of clinical chemistry.

Effects of pioglitazone hydrochloride on Japanese patients with type 2 diabetes mellitus.

N. Yamada, K. Shirai, T. Teramoto, 2007, Journal of atherosclerosis and thrombosis.

Author's Reply to: Central Blood Pressure: A Possible Latent Factor Affecting CAVI

K. Shirai, Mao Takahashi, 2011 .

Low preheparin serum lipoprotein lipase mass is an independent risk factor for acute myocardial infarction

Y. Miyashita, K. Shirai, T. Hitsumoto, 2002 .

Enhanced circulating soluble LR11 in patients with diabetic retinopathy.

K. Shirai, T. Maeno, T. Shiba, 2012, American journal of ophthalmology.

Enhanced circulating soluble LR11 in patients with coronary organic stenosis.

K. Shirai, Mao Takahashi, H. Bujo, 2010, Atherosclerosis.

Comparative study of cardio-ankle vascular index between Chinese and Japanese healthy subjects

Hongyu Wang, Jinbo Liu, Xiaobao Fu, 2014, Clinical and experimental hypertension.

Improvement of postprandial hyperglycemia and arterial stiffness upon switching from premixed human insulin 30/70 to biphasic insulin aspart 30/70.

A. Saiki, T. Oyama, K. Endo, 2011, Metabolism: clinical and experimental.

Effect of glycyrrhizin on lysosomes labilization by phospholipase A2.

K. Shirai, Y. Saito, S. Yoshida, 1986, The American journal of Chinese medicine.

Effects of adrenergic blocking agents on lipolysis and adenyl cyclase activity induced by vasoactive intestinal polypeptide (VIP).

K. Shirai, N. Yanaihara, Y. Saito, 1978, Endocrinologia japonica.

Modification of intracellular glucose metabolism in human skin fibroblast preincubated with p-chlorophenoxyisobutyrate.

T. Nishide, K. Shirai, Y. Saito, 1987, British journal of clinical pharmacology.

Association of Prediabetes and Diabetes Mellitus with Cardiovascular Disease Risk Factors among Japanese Urban Workers and their Families: A Cross-Sectional Study

K. Shirai, Kenji Suzuki, M. Nakata, 2014 .

Medical science is based on evidence (answer to Spronck et al.'s refutation: physics cannot be disputed).

K. Shirai, A. Takahara, M. Takata, 2018, Journal of hypertension.

A Case Demonstrating the Cardio-Vascular Interaction by a New Cardio-Ankle Vascular Index During the Treatment of Concentric Hypertrophy

Shuji Sato, K. Shirai, K. Shimizu, 2019, Cardiology research.

Clinical Significance of Plasma 7-ketocholesterol Concentrations in Patients with Coronary Vasospastic Angina Pectoris(Angina Pectoris, Basic/Clinical 6 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

Y. Miyashita, K. Shirai, T. Hitsumoto, 2005 .

OS 10-04 INVERSE RELATIONSHIP BETWEEN CARDIO-ANKLE VASCULAR INDEX (CAVI) AND BODY MASS INDEX IN HEALTHY JAPANESE SUBJECTS: A CROSS-SECTIONAL STUDY.

I. Tatsuno, A. Saiki, M. Ohira, 2016, Journal of Hypertension.

OS 10-04 INVERSE RELATIONSHIP BETWEEN CARDIO-ANKLE VASCULAR INDEX (CAVI) AND BODY MASS INDEX IN HEALTHY JAPANESE SUBJECTS: A CROSS-SECTIONAL STUDY.

I. Tatsuno, A. Saiki, M. Ohira, 2016, Journal of Hypertension.

Association of Cardio-Ankle Vascular Index with Cardiovascular Disease Risk Factors and Coronary Heart Disease among Japanese Urban Workers and their Families

K. Shirai, Kenji Suzuki, M. Nakata, 2011 .

Effect of ezetimibe monotherapy on lipid metabolism and arterial stiffness assessed by cardio-ankle vascular index in type 2 diabetic patients.

A. Saiki, T. Oyama, K. Endo, 2010, Journal of atherosclerosis and thrombosis.

Parkinson's disease and the cardio-ankle vascular stiffness index.

R. Sakakibara, K. Shirai, T. Tomaru, 2014, Internal medicine.

Beta-VLDL-induced cholesterol ester deposition in macrophages may be regulated by neutral cholesterol esterase activity.

K. Shirai, M. Oka, Y. Saito, 1992, Arteriosclerosis and thrombosis : a journal of vascular biology.

Reasons for the Decline of Cardio-Ankle Vascular Index (CAVI) in Aortic Valve Stenosis (AVS) [Letter]

K. Shirai, Tomoyuki Yamamoto, Koji Takahashi, 2022, Vascular health and risk management.

Effects of serotonin on expression of the LDL receptor family member LR11 and 7-ketocholesterol-induced apoptosis in human vascular smooth muscle cells.

I. Tatsuno, K. Shirai, H. Bujo, 2014, Biochemical and Biophysical Research Communications - BBRC.

Abdominal wall fat index, estimated by ultrasonography, for assessment of the ratio of visceral fat to subcutaneous fat in the abdomen.

R. Suzuki, S. Watanabe, Y. Hirai, 1993, The American journal of medicine.

Reduction of visceral adiposity after operation in a subject with insulinoma.

A. Saiki, Y. Miyashita, K. Shirai, 2004, Journal of atherosclerosis and thrombosis.

Effect of apolipoproteins on the hepatic lipase-catalyzed hydrolysis of human plasma high density lipoprotein2-triacylglycerols.

M. Shinomiya, K. Shirai, R. Jackson, 1982, Biochimica et biophysica acta.

Lipid metabolism in the aorta and the brain microvessels of rabbits on high cholesterol diet.

M. Shinomiya, K. Shirai, N. Morisaki, 1982, Artery.

Rapid Rise in Cardio-Ankle Vascular Index as a Predictor of Impending Cardiovascular Events -Smooth Muscle Cell Contraction Hypothesis for Plaque Rupture -

Shuji Sato, A. Saiki, K. Shirai, 2022, Vascular Health and Risk Management.

Analysis of effects of acute hypovolemia on arterial stiffness in rabbits monitored with cardio-ankle vascular index.

C. Miyazaki, Shuji Sato, Y. Nagasawa, 2022, Journal of pharmacological sciences.

Increased Arterial Stiffness in Chronic Thromboembolic Pulmonary Hypertension Was Improved with Riociguat and Balloon Pulmonary Angioplasty: A Case Report

Shuji Sato, Takuro Ito, K. Shirai, 2021, International medical case reports journal.

EFFECT OF NEW CHYMOTRYPSIN INHIBITOR (FK-448) ON INTESTINAL ABSORPTION OF INSULIN

M. Shinomiya, K. Shirai, S. Yoshida, 1985, The Lancet.

Vitreous fluid and circulating levels of soluble lr11, a novel marker for progression of diabetic retinopathy

K. Shirai, T. Maeno, T. Shiba, 2013, Graefe's Archive for Clinical and Experimental Ophthalmology.

Cytotoxicity of some oxysterols on human vascular smooth muscle cells was mediated by apoptosis.

Y. Urano, T. Murano, Y. Miyashita, 1997, Journal of atherosclerosis and thrombosis.