A. Nohara

发表

Serum lipoprotein lipase mass: clinical significance of its measurement.

H. Mabuchi, J. Kobayashi, A. Nohara, 2007, Clinica chimica acta; international journal of clinical chemistry.

Novel mutations of cholesteryl ester transfer protein (CETP) gene in Japanese hyperalphalipoproteinemic subjects.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2012, Clinica chimica acta; international journal of clinical chemistry.

Long-term treatment with pitavastatin (NK-104), a new HMG-CoA reductase inhibitor, of patients with heterozygous familial hypercholesterolemia.

H. Mabuchi, A. Nohara, Akihiro Inazu, 2002, Atherosclerosis.

Aortic Root Calcification Score as an Independent Factor for Predicting Major Adverse Cardiac Events in Familial Hypercholesterolemia

K. Hayashi, M. Yamagishi, H. Mabuchi, 2018, Journal of atherosclerosis and thrombosis.

High frequency of type 2 diabetes and impaired glucose tolerance in Japanese subjects with the angiopoietin-like protein 8 R59W variant.

M. Yamagishi, J. Kobayashi, A. Nohara, 2017, Journal of clinical lipidology.

Abstract 18157: Impact of Betatrophin (ANGPTL8) R59W Mutation for Future Diabetes, and Minimal Modification of Circulating Betatrophin With Strong Statins

M. Yamagishi, H. Mabuchi, A. Nohara, 2015 .

Molecular genetic analysis of familial hypercholesterolemia: spectrum and regional difference of LDL receptor gene mutations in Japanese population.

H. Mabuchi, A. Nohara, Akihiro Inazu, 2002, Atherosclerosis.

ATP-binding cassette transporter G8 M429V polymorphism as a novel genetic marker of higher cholesterol absorption in hypercholesterolaemic Japanese subjects.

H. Mabuchi, J. Kobayashi, A. Nohara, 2005, Clinical science.

Raloxifene promotes adipocyte differentiation of 3T3-L1 cells.

Hiroshi Sato, H. Mabuchi, J. Kobayashi, 2006, European journal of pharmacology.

Retinoid X receptor heterodimer variants and cardiovascular risk factors.

H. Mabuchi, J. Kobayashi, A. Nohara, 2009, Journal of atherosclerosis and thrombosis.

Guidelines for Diagnosis and Treatment of Familial Hypercholesterolemia 2017

S. Yamashita, T. Okamura, H. Arai, 2018, Journal of atherosclerosis and thrombosis.

Special Report Guidelines for the Management of Familial Hypercholesterolemia

S. Yamashita, T. Okamura, H. Arai, 2012 .

Relationships between alanine aminotransferase (ALT), visceral adipose tissue (AT) and metabolic risk factors in a middle-aged Japanese population.

K. Hayashi, M. Yamagishi, A. Nohara, 2014, Journal of atherosclerosis and thrombosis.

Comparison of waist circumference with body mass index for predicting abdominal adipose tissue.

M. Yamagishi, K. Miura, H. Mabuchi, 2009, Diabetes research and clinical practice.

Cholesteryl ester transfer protein inhibitor (JTT-705) and the development of atherosclerosis in rabbits with severe hypercholesterolaemia.

H. Mabuchi, A. Nohara, Akihiro Inazu, 2002, Clinical science.

Characterization of Autosomal Dominant Hypercholesterolemia Caused by PCSK9 Gain of Function Mutations and Its Specific Treatment With Alirocumab, a PCSK9 Monoclonal Antibody

M. Krempf, G. Luc, P. Hopkins, 2015, Circulation. Cardiovascular genetics.

Insulin secretion and insulin sensitivity on the oral glucose tolerance test (OGTT) in middle-aged Japanese.

M. Yamagishi, A. Nohara, M. Kawashiri, 2012, Endocrine journal.

Controversy around airborne versus droplet transmission of respiratory viruses: implication for infection prevention.

B. Cowling, A. Nohara, M. Kawashiri, 2019, Current opinion in infectious diseases.

Reduction of serum ubiquinol-10 and ubiquinone-10 levels by atorvastatin in hypercholesterolemic patients.

H. Mabuchi, J. Kobayashi, A. Nohara, 2005, Journal of atherosclerosis and thrombosis.

Marked aortic valve stenosis progression after receiving long-term aggressive cholesterol-lowering therapy using low-density lipoprotein apheresis in a patient with familial hypercholesterolemia.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2009, Circulation journal : official journal of the Japanese Circulation Society.

Efficacy of colestimide coadministered with atorvastatin in japanese patients with heterozygous familial hypercholesterolemia (FH).

H. Mabuchi, J. Kobayashi, A. Nohara, 2005, Circulation journal : official journal of the Japanese Circulation Society.

Type III hyperlipoproteinemia exaggerated by Sheehan's syndrome with advanced systemic atherosclerosis: a 28-year clinical course.

H. Mabuchi, J. Kobayashi, A. Nohara, 2005, Circulation journal : official journal of the Japanese Circulation Society.

Impact of anti-apoptotic and anti-oxidative effects of bone marrow mesenchymal stem cells with transient overexpression of heme oxygenase-1 on myocardial ischemia.

Masahiko Zuka, M. Yamagishi, H. Ishibashi-Ueda, 2010, American journal of physiology. Heart and circulatory physiology.

Changes in lipoprotein lipase and endothelial lipase mass in familial hypercholesterolemia during three-drug lipid-lowering combination therapy

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2016, Lipids in Health and Disease.

Lipid Management in a Japanese Community: Attainment Rate of Target Set by the Japan Atherosclerosis Society Guidelines for the Prevention of Atherosclerotic Cardiovascular Diseases 2012

K. Hayashi, M. Yamagishi, H. Mabuchi, 2017, Journal of atherosclerosis and thrombosis.

The E32K variant of PCSK9 exacerbates the phenotype of familial hypercholesterolaemia by increasing PCSK9 function and concentration in the circulation.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2010, Atherosclerosis.

Familial Hypercholesterolemia in Patients with Acute Coronary Syndrome: Genetic Insights from EXPLORE-J

A. Hirayama, H. Arai, Masato Nakamura, 2021, Journal of atherosclerosis and thrombosis.

Prevalence of familial hypercholesterolemia in patients with acute coronary syndrome in Japan: Results of the EXPLORE-J study.

A. Hirayama, H. Arai, Y. Murakami, 2018, Atherosclerosis.

CETP (cholesteryl ester transfer protein) promoter -1337 C>T polymorphism protects against coronary atherosclerosis in Japanese patients with heterozygous familial hypercholesterolaemia.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2006, Clinical science.

Impact of bezafibrate and atorvastatin on lipoprotein subclass in patients with type III hyperlipoproteinemia: result from a crossover study.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2011, Clinica chimica acta; international journal of clinical chemistry.

Effects of Fenofibrate Therapy on Plasma Ubiquinol‐10 and Ubiquinone‐10 Levels in Japanese Patients with Hyperlipidemia and Type 2 Diabetes Mellitus

H. Mabuchi, J. Kobayashi, A. Nohara, 2006, Pharmacotherapy.

Effects of CoQ10 supplementation on plasma lipoprotein lipid, CoQ10 and liver and muscle enzyme levels in hypercholesterolemic patients treated with atorvastatin: a randomized double-blind study.

H. Mabuchi, J. Kobayashi, A. Nohara, 2007, Atherosclerosis.

Reducing the Clinical and Public Health Burden of Familial Hypercholesterolemia: A Global Call to Action.

C. Aguilar-Salinas, G. Mensah, G. Watts, 2020, JAMA cardiology.

Guidelines for the management of familial hypercholesterolemia.

S. Yamashita, T. Okamura, H. Arai, 2012, Journal of atherosclerosis and thrombosis.

Association of coronary artery ectasia with plasma insulin levels in Japanese men of heterozygous familial hypercholesterolemia with the low-density lipoprotein receptor gene mutation K790X.

H. Mabuchi, J. Kobayashi, A. Nohara, 2005, Clinica chimica acta; international journal of clinical chemistry.

Effect of walking with a pedometer on serum lipid and adiponectin levels in Japanese middle-aged men.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2006, Journal of atherosclerosis and thrombosis.

Assessments of Carotid Artery Plaque Burden in Patients With Familial Hypercholesterolemia.

K. Hayashi, M. Yamagishi, H. Mabuchi, 2017, The American journal of cardiology.

Epicardial Adipose Tissue as a Predictor of Plaque Vulnerability in Patients With Mild Chronic Kidney Disease.

A. Nohara, 2016, Circulation journal : official journal of the Japanese Circulation Society.

Multicenter study to determine the diagnosis criteria of heterozygous familial hypercholesterolemia in Japan.

S. Yamashita, T. Okamura, H. Arai, 2012, Journal of atherosclerosis and thrombosis.

Prevalent Coronary Artery Disease and Undertreatment in Heterozygous Familial Hypercholesterolemia -Real-World Data and “Heterozygous FH Score” from FAME Study-

A. Nohara, 2022, Journal of atherosclerosis and thrombosis.

Genetic mutations, regression of Achilles tendon thickness, and cardiovascular events among patients with familial hypercholesterolemia.

A. Nohara, H. Tada, H. Okada, 2021, Atherosclerosis.

A reassessment of the Japanese clinical diagnostic criteria of familial hypercholesterolemia in a hospital-based cohort using comprehensive genetic analysis

A. Nohara, M. Kawashiri, H. Tada, 2020, Practical laboratory medicine.

Effects of Different Types of Pathogenic Variants on Phenotypes of Familial Hypercholesterolemia

A. Nohara, M. Kawashiri, H. Tada, 2022, Frontiers in Genetics.

Homozygous Familial Hypercholesterolemia

H. Daida, K. Matsuki, S. Yokoyama, 2021, Journal of atherosclerosis and thrombosis.

Clinical Diagnostic Criteria of Familial Hypercholesterolemia　- A Comparison of the Japan Atherosclerosis Society and Dutch Lipid Clinic Network Criteria.

M. Yamagishi, A. Nohara, M. Kawashiri, 2020, Circulation journal : official journal of the Japanese Circulation Society.

Difference between fasting and nonfasting triglyceridemia; the influence of waist circumference.

M. Yamagishi, K. Miura, H. Mabuchi, 2009, Journal of atherosclerosis and thrombosis.

Cholesterol efflux from J774 macrophages and Fu5AH hepatoma cells to serum is preserved in CETP-deficient patients.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2009, Clinica chimica acta; international journal of clinical chemistry.

Efficacy and Safety of Lomitapide in Japanese Patients with Homozygous Familial Hypercholesterolemia

A. Nohara, M. Harada‐Shiba, K. Ikewaki, 2017, Journal of atherosclerosis and thrombosis.

Homozygous familial hypercholesterolemia Efficacy and Safety of Lomitapide in Japanese Patients with Homozygous Familial Hypercholesterolemia

A. Nohara, M. Harada‐Shiba, K. Ikewaki, 2017 .

Optimal Treatment using Statins from Childhood in Heterozygous Familial Hypercholesterolemia.

A. Nohara, 2016, Journal of atherosclerosis and thrombosis.

Molecular genetic epidemiology of homozygous familial hypercholesterolemia in the Hokuriku district of Japan.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2011, Atherosclerosis.

Long-term course of lipoprotein lipase (LPL) deficiency due to homozygous LPL(Arita) in a patient with recurrent pancreatitis, retained glucose tolerance, and atherosclerosis.

H. Mabuchi, J. Kobayashi, A. Nohara, 2005, The Journal of clinical endocrinology and metabolism.

The distribution of fasting and non-fasting serum triglyceride levels in Japanese population.

H. Mabuchi, J. Kobayashi, A. Nohara, 2006, Clinica chimica acta; international journal of clinical chemistry.

Comparison of effects of bezafibrate and fenofibrate on circulating proprotein convertase subtilisin/kexin type 9 and adipocytokine levels in dyslipidemic subjects with impaired glucose tolerance or type 2 diabetes mellitus: results from a crossover study.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2011, Atherosclerosis.

Hokuriku-plus familial hypercholesterolaemia registry study: rationale and study design

K. Hayashi, M. Yamaguchi, H. Murai, 2020, BMJ Open.

A case with familial hypercholesterolemia complicated with severe systemic atherosclerosis intensively treated for more than 30 years.

K. Ino, A. Nohara, M. Kawashiri, 2020, Journal of cardiology cases.

Serum Sitosterol Level Predicting ABCG5 or ABCG8 Genetic Mutations.

K. Hayashi, A. Nohara, M. Kawashiri, 2020, Clinica chimica acta; international journal of clinical chemistry.

Clinical Impact of Carotid Plaque Score rather than Carotid Intima-Media Thickness on Recurrence of Atherosclerotic Cardiovascular Disease Events

A. Nohara, M. Kawashiri, H. Tada, 2020, Journal of atherosclerosis and thrombosis.

Remnant-like particles and coronary artery disease in familial hypercholesterolemia.

K. Hayashi, M. Yamagishi, H. Mabuchi, 2018, Clinica chimica acta; international journal of clinical chemistry.

Oligogenic familial hypercholesterolemia, LDL cholesterol, and coronary artery disease.

M. Yamagishi, H. Mabuchi, A. Tajima, 2018, Journal of clinical lipidology.

Lipoprotein(a) in Familial Hypercholesterolemia With Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Gain-of-Function Mutations.

K. Hayashi, M. Yamagishi, H. Mabuchi, 2016, Circulation journal : official journal of the Japanese Circulation Society.

Clinical characteristics of Japanese patients with severe hypertriglyceridemia.

K. Hayashi, M. Yamagishi, H. Mabuchi, 2015, Journal of clinical lipidology.

Clinical efficacy and safety of rosuvastatin in Japanese patients with heterozygous familial hypercholesterolemia.

H. Mabuchi, A. Nohara, Y. Ikeda, 2004, Journal of atherosclerosis and thrombosis.

Impact of evolocumab treatment on low-density lipoprotein cholesterol levels in heterozygous familial hypercholesterolemic patients withdrawing from regular apheresis.

K. Hayashi, M. Yamagishi, H. Mabuchi, 2017, Atherosclerosis.

Dual effects on HDL metabolism by cholesteryl ester transfer protein inhibition in HepG2 cells.

H. Mabuchi, A. Nohara, M. Kawashiri, 2003, American journal of physiology. Endocrinology and metabolism.

Extreme Contrast of Postprandial Remnant-Like Particles Formed in Abetalipoproteinemia and Homozygous Familial Hypobetalipoproteinemia.

K. Hayashi, M. Yamagishi, H. Mabuchi, 2015, JIMD reports.

Apolipoprotein B gene mutations and fatty liver in Japanese hypobetalipoproteinemia.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2009, Clinica chimica acta; international journal of clinical chemistry.

Postprandial triglyceridaemia in men with impaired fasting glucose, impaired glucose tolerance and diabetes

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2008, Diabetic medicine : a journal of the British Diabetic Association.

Increased circulating matrix metalloproteinase-2 in patients with hypertrophic cardiomyopathy with systolic dysfunction.

H. Mabuchi, M. Yamaguchi, A. Nohara, 2004, Circulation journal : official journal of the Japanese Circulation Society.

Relationships of serum haptoglobin concentration with HbA1c and glycated albumin concentrations in Japanese type 2 diabetic patients

M. Yamagishi, J. Kobayashi, A. Nohara, 2009, Clinical chemistry and laboratory medicine.

A novel method for determining functional LDL receptor activity in familial hypercholesterolemia: application of the CD3/CD28 assay in lymphocytes.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2009, Clinica chimica acta; international journal of clinical chemistry.

Therapy: PCSK9 inhibitors for treating familial hypercholesterolaemia

H. Mabuchi, A. Nohara, 2015, Nature Reviews Endocrinology.

A Healthy Family of Familial Hypobetalipoproteinemia Caused by a Protein-truncating Variant in the PCSK9 Gene

A. Nohara, M. Kawashiri, H. Tada, 2020, Internal medicine.

A novel type of familial hypercholesterolemia: double heterozygous mutations in LDL receptor and LDL receptor adaptor protein 1 gene.

K. Hayashi, M. Yamagishi, H. Mabuchi, 2011, Atherosclerosis.

Association of estrogen receptor-alpha gene polymorphisms with coronary artery disease in patients with familial hypercholesterolemia.

H. Mabuchi, A. Nohara, Akihiro Inazu, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Association of Estrogen Receptor-Gene Polymorphisms With Coronary Artery Disease in Patients With Familial Hypercholesterolemia

H. Mabuchi, A. Nohara, Akihiro Inazu, 2002 .

Effect of Cumulative Exposure to Low-Density Lipoprotein-Cholesterol on Cardiovascular Events in Patients With Familial Hypercholesterolemia.

M. Yamagishi, A. Nohara, M. Kawashiri, 2021, Circulation journal : official journal of the Japanese Circulation Society.

Prognostic impact of cascade screening for familial hypercholesterolemia on cardiovascular events.

M. Yamagishi, A. Nohara, M. Kawashiri, 2020, Journal of clinical lipidology.

Oral Fat Tolerance Test for Sitosterolemia and Familial Hypercholesterolemia: A Study Protocol

M. Yamagishi, A. Nohara, M. Kawashiri, 2018, Journal of atherosclerosis and thrombosis.

Dietary Intake during 56 Weeks of a Low-Fat Diet for Lomitapide Treatment in Japanese Patients with Homozygous Familial Hypercholesterolemia

A. Nohara, M. Harada‐Shiba, K. Ikewaki, 2019, Journal of atherosclerosis and thrombosis.

Familial hypercholesterolemia.

S. Kihara, S. Yamashita, T. Hiro, 2014, Journal of atherosclerosis and thrombosis.

Genotypic and phenotypic features in homozygous familial hypercholesterolemia caused by proprotein convertase subtilisin/kexin type 9 (PCSK9) gain-of-function mutation.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2014, Atherosclerosis.

Effects of coenzyme Q(10) on LDL oxidation in vitro.

H. Mabuchi, A. Nohara, M. Kawashiri, 2013, Acta medica Iranica.

Lipoprotein metabolism in familial hypercholesterolemia: Serial assessment using a one-step ultracentrifugation method

K. Hayashi, M. Yamagishi, H. Mabuchi, 2015, Practical laboratory medicine.

Infantile Cases of Sitosterolaemia with Novel Mutations in the ABCG5 Gene: Extreme Hypercholesterolaemia is Exacerbated by Breastfeeding.

K. Hayashi, M. Yamagishi, H. Mabuchi, 2015, JIMD reports.

Safety and Efficacy of Lomitapide in Japanese Patients with Homozygous Familial Hypercholesterolemia (HoFH): Results from the AEGR-733-301 Long-Term Extension Study

A. Nohara, M. Harada‐Shiba, K. Ikewaki, 2019, Journal of atherosclerosis and thrombosis.

Detailed analysis of serum lipids and lipoproteins from Japanese type III hyperlipoproteinemia with apolipoprotein E2/2 phenotype.

H. Mabuchi, J. Kobayashi, A. Nohara, 2004, Clinica chimica acta; international journal of clinical chemistry.

Comparison of the effects of losartan vs. ramipril on several adipocytokines and vascular remodeling biomarkers

H. Mabuchi, J. Kobayashi, A. Nohara, 2011, Hypertension Research.

Identification of a novel missense mutation in the sterol 27-hydroxylase gene in two Japanese patients with cerebrotendinous xanthomatosis.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2010, Internal medicine.

Statement for Appropriate Clinical Use of PCSK9 Inhibitors

S. Yamashita, K. Kitagawa, K. Tsukamoto, 2018, Journal of atherosclerosis and thrombosis.

Decreased post-prandial triglyceride response and diminished remnant lipoprotein formation in cholesteryl ester transfer protein (CETP) deficiency.

H. Mabuchi, J. Kobayashi, A. Nohara, 2008, Atherosclerosis.

Autosomal recessive hypercholesterolemia: a mild phenotype of familial hypercholesterolemia: insight from the kinetic study using stable isotope and animal studies.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2015, Journal of atherosclerosis and thrombosis.

Absence of familial defective apolipoprotein B-100 in Japanese patients with familial hypercholesterolaemia

H. Mabuchi, A. Nohara, Akihiro Inazu, 1995, The Lancet.

Running title: Stitziel et al., Exome Sequencing in Monogenic Dyslipidemias

S. Gabriel, M. Daly, D. Nickerson, 2015 .

Whole Exome Sequencing Insufficient for a Definitive Diagnosis of a Patient with Compound Heterozygous Familial Hypercholesterolemia

A. Nohara, M. Kawashiri, H. Tada, 2022, Internal medicine.

Post-prandial Remnant Lipoprotein Metabolism in Sitosterolemia

M. Yamagishi, H. Mabuchi, A. Nohara, 2018, Journal of atherosclerosis and thrombosis.

Marked transient hypercholesterolemia caused by low-dose mitotane as adjuvant chemotherapy for adrenocortical carcinoma.

M. Yamagishi, H. Mabuchi, A. Nohara, 2014, Journal of atherosclerosis and thrombosis.

Post‐prandial remnant lipoprotein metabolism in autosomal recessive hypercholesterolaemia

K. Hayashi, M. Yamagishi, H. Mabuchi, 2012, European journal of clinical investigation.

Altered Metabolism of Low-Density Lipoprotein and Very-Low-Density Lipoprotein Remnant in Autosomal Recessive Hypercholesterolemia: Results From Stable Isotope Kinetic Study In Vivo

K. Hayashi, M. Yamagishi, H. Mabuchi, 2012, Circulation. Cardiovascular genetics.

Impact of variants of uncertain significance of LDL receptor on phenotypes of familial hypercholesterolemia.

A. Nohara, M. Kawashiri, H. Tada, 2022, Journal of clinical lipidology.

The Japanese Society for Apheresis clinical practice guideline for therapeutic apheresis

Y. Takikawa, M. Kusaoi, T. Okado, 2021, Therapeutic apheresis and dialysis.

Early diagnosis and treatments in childhood are associated with better prognosis in patients with familial hypercholesterolemia

A. Nohara, M. Kawashiri, H. Tada, 2022, American journal of preventive cardiology.

Clinical whole exome sequencing in severe hypertriglyceridemia.

K. Hayashi, M. Yamagishi, H. Mabuchi, 2019, Clinica chimica acta; international journal of clinical chemistry.

Sitosterolemia, Hypercholesterolemia, and Coronary Artery Disease

H. Mabuchi, A. Nohara, M. Kawashiri, 2018, Journal of atherosclerosis and thrombosis.

Functional Characterization of Rare Variants Implicated in Susceptibility to Lone Atrial Fibrillation

K. Hayashi, M. Yamagishi, N. Makita, 2022 .

Exploration into lipid management and persistent risk in patients hospitalised for acute coronary syndrome in Japan (EXPLORE-J): protocol for a prospective observational study

A. Hirayama, H. Arai, Masato Nakamura, 2017, BMJ Open.

Impact of genetic testing on low-density lipoprotein cholesterol in patients with familial hypercholesterolemia (GenTLe-FH): a randomised waiting list controlled open-label study protocol

H. Ishikawa, A. Nohara, M. Kawashiri, 2018, BMJ Open.

Changes in lipoprotein lipase and endothelial lipase mass in familial hypercholesterolemia during three-drug lipid-lowering combination therapy

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2016, Lipids in Health and Disease.

Lipid Management and 2-Year Clinical Outcomes in Japanese Patients with Acute Coronary Syndrome: EXPLORE-J

A. Hirayama, H. Arai, Y. Murakami, 2021, Journal of atherosclerosis and thrombosis.

Rare Protein-Truncating Variants in APOB, Lower Low-Density Lipoprotein Cholesterol, and Protection Against Coronary Heart Disease

Tanya M. Teslovich, J. Danesh, S. McCarthy, 2019, Circulation. Genomic and precision medicine.

Exome Sequencing in Suspected Monogenic Dyslipidemias

Rahul C. Deo, S. Gabriel, M. Daly, 2015, Circulation. Cardiovascular genetics.

Impact of clinical signs and genetic diagnosis of familial hypercholesterolaemia on the prevalence of coronary artery disease in patients with severe hypercholesterolaemia

M. Yamagishi, H. Mabuchi, A. Nohara, 2017, European heart journal.

Cholesteryl Ester Transfer Protein (CETP) Deficiency and CETP Inhibitors

H. Mabuchi, A. Nohara, Akihiro Inazu, 2014, Molecules and cells.

Reassessment of the cutoff values of waist circumference and visceral fat area for identifying Japanese subjects at risk for the metabolic syndrome.

M. Yamagishi, H. Mabuchi, H. Tanii, 2008, Diabetes research and clinical practice.

Achilles Tendon Thickness Assessed by X-ray Predicting a Pathogenic Mutation in Familial Hypercholesterolemia Gene

K. Matsuki, A. Nohara, M. Kawashiri, 2021, Journal of atherosclerosis and thrombosis.

Rare and Deleterious Mutations in ABCG5/ABCG8 Genes Contribute to Mimicking and Worsening of Familial Hypercholesterolemia Phenotype.

A. Nohara, M. Kawashiri, H. Tada, 2019, Circulation journal : official journal of the Japanese Circulation Society.

A de novo mutation of the LDL receptor gene as the cause of familial hypercholesterolemia identified using whole exome sequencing.

K. Hayashi, H. Mabuchi, A. Tajima, 2016, Clinica chimica acta; international journal of clinical chemistry.

Impact of B-Type Natriuretic Peptide Level on Risk Stratification of Thromboembolism and Death in Patients With Nonvalvular Atrial Fibrillation　- The Hokuriku-Plus AF Registry.

K. Hayashi, M. Yamagishi, A. Nohara, 2018, Circulation journal : official journal of the Japanese Circulation Society.

Synergistic effect of lipoprotein (a) and C-reactive protein on prognosis of familial hypercholesterolemia

A. Nohara, M. Kawashiri, H. Tada, 2022, American journal of preventive cardiology.

Identification of two novel missense mutations (p.R1221C and p.R1357W) in the ABCC6 (MRP6) gene in a Japanese patient with pseudoxanthoma elasticum (PXE).

H. Mabuchi, A. Nohara, M. Kawashiri, 2004, Internal medicine.

Remnant lipoproteins and atherosclerotic cardiovascular disease.

H. Mabuchi, A. Nohara, M. Kawashiri, 2019, Clinica chimica acta; international journal of clinical chemistry.

High Frequency of a Retinoid X Receptor &ggr; Gene Variant in Familial Combined Hyperlipidemia That Associates With Atherogenic Dyslipidemia

Masayuki Tsuchida, Kenji Miwa, Shoji Katsuda, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Prevalence, clinical features, and prognosis of patients with extremely low high-density lipoprotein cholesterol.

K. Hayashi, M. Yamagishi, H. Mabuchi, 2016, Journal of clinical lipidology.

Whole exome sequencing combined with integrated variant annotation prediction identifies asymptomatic Tangier disease with compound heterozygous mutations in ABCA1 gene.

K. Hayashi, M. Yamagishi, Reina Saito, 2015, Atherosclerosis.

Impacts of Visceral Adipose Tissue and Subcutaneous Adipose Tissue on Metabolic Risk Factors in Middle‐aged Japanese

Yoshiyu Takeda, Kunimasa Yagi, M. Yamagishi, 2010, Obesity.

Impact of gastrectomy on high-density lipoprotein cholesterol elevation in nonobese patients during a 10-year follow-up.

A. Suzuki, M. Yamagishi, A. Nohara, 2015, Journal of atherosclerosis and thrombosis.

Guidance for Pediatric Familial Hypercholesterolemia 2017

S. Yamashita, K. Yokote, A. Nohara, 2018, Journal of atherosclerosis and thrombosis.

JCS 2018 Guideline on Diagnosis of Chronic Coronary Heart Diseases.

M. Miyagawa, M. Jinzaki, W. Shimizu, 2021, Circulation journal : official journal of the Japanese Circulation Society.

Impact of Serum Retinol-Binding Protein 4 Levels on Regulation of Remnant-Like Particles Triglyceride in Type 2 Diabetes Mellitus

M. Yamagishi, J. Kobayashi, A. Nohara, 2013, Journal of diabetes research.

The relationship of percent body fat by bioelectrical impedance analysis with blood pressure, and glucose and lipid parameters.

H. Mabuchi, J. Kobayashi, A. Nohara, 2006, Journal of atherosclerosis and thrombosis.

Efficacy and safety of coadministration of rosuvastatin, ezetimibe, and colestimide in heterozygous familial hypercholesterolemia.

K. Hayashi, M. Yamagishi, H. Mabuchi, 2012, The American journal of cardiology.

Decreased ADP-Ribosyl Cyclase Activity in Peripheral Blood Mononuclear Cells from Diabetic Patients with Nephropathy

M. Yamagishi, H. Higashida, J. Kobayashi, 2009, Experimental diabetes research.

ResearchArticle Decreased ADP-Ribosyl Cyclase Activity in Peripheral Blood Mononuclear Cells from Diabetic Patients with Nephropathy

M. Yamagishi, H. Higashida, J. Kobayashi, 2008 .

Efficacy and Safety of Alirocumab in Japanese Patients With Heterozygous Familial Hypercholesterolemia or at High Cardiovascular Risk With Hypercholesterolemia Not Adequately Controlled With Statins　- ODYSSEY JAPAN Randomized Controlled Trial.

A. Nohara, T. Teramoto, T. Higashikata, 2016, Circulation journal : official journal of the Japanese Circulation Society.

A Rare Coincidence of Sitosterolemia and Familial Mediterranean Fever Identified by Whole Exome Sequencing.

K. Hayashi, M. Yamagishi, Y. Toyoshima, 2016, Journal of atherosclerosis and thrombosis.

Monogenic, polygenic, and oligogenic familial hypercholesterolemia.

A. Nohara, M. Kawashiri, H. Tada, 2019, Current opinion in lipidology.

Monogenic, polygenic, and oligogenic familial hypercholesterolemia

A. Nohara, M. Kawashiri, H. Tada, 2019, Current Opinion in Lipidology.

P-214 Clinical Impact of Heterozygous Carrier of Autosomal Recessive Hypercholesterolemia on Asymptomatic Hyperlipidemic Patients

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2009 .

Abstract 1921: Clinical Impact of Heterozygous Carrier of Autosomal Recessive Hypercholesterolemia on Asymptomatic Hyperlipidemic Patients: Evidence From Familial Gene Analysis

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2008 .

Impact of visceral adipose tissue and subcutaneous adipose tissue on insulin resistance in middle-aged Japanese.

K. Hayashi, M. Yamagishi, A. Nohara, 2012, Journal of atherosclerosis and thrombosis.

Formation of prebeta1-HDL during lipolysis of triglyceride-rich lipoprotein.

Atsuo Mori, M. Yamagishi, H. Mabuchi, 2009, Biochemical and biophysical research communications.

Investigation into Lipid Management in Acute Coronary Syndrome Patients from the EXPLORE-J Study

A. Hirayama, H. Arai, Y. Murakami, 2019, Journal of atherosclerosis and thrombosis.

Impact of Healthy Lifestyle in Patients With Familial Hypercholesterolemia

A. Nohara, M. Kawashiri, H. Tada, 2023, JACC. Asia.

Assessment of coronary atherosclerosis in patients with familial hypercholesterolemia by coronary computed tomography angiography.

K. Hayashi, M. Yamagishi, H. Mabuchi, 2015, The American journal of cardiology.

Impact of Providing Future Cardiovascular Risk Based on Genetic Testing on Low-Density Lipoprotein Cholesterol in Patients with Familial Hypercholesterolemia (GenTLe-FH): A Randomized Wait-list Controlled Open-Label Trial

A. Nohara, H. Tada, A. Nomura, 2023, medRxiv.

Title Assessment of Coronary atherosclerosis in patients with familialhypercholesterolemia by coronary computed tomography angiography

K. Hayashi, M. Yamagishi, H. Mabuchi, 2017 .

What Can Be Seen From “Intracranial-Vascular”-Susceptibility Genetic Factor in “Cardiovascular-Susceptible” Familial Hypercholesterolemia

A. Nohara, 2023, JACC: Asia.

Coronary artery calcium among patients with heterozygous familial hypercholesterolaemia

A. Nohara, M. Kawashiri, H. Tada, 2023, European heart journal open.

Impact of High-Density Lipoprotein Function, Rather Than High-Density Lipoprotein Cholesterol Level, on Cardiovascular Disease Among Patients With Familial Hypercholesterolemia.

A. Nohara, M. Kawashiri, H. Tada, 2022, Circulation journal : official journal of the Japanese Circulation Society.

A catalog of the pathogenic mutations of LDL receptor gene in Japanese familial hypercholesterolemia.

A. Nohara, M. Kawashiri, H. Tada, 2020, Journal of clinical lipidology.

Assessment of arterial stiffness in patients with familial hypercholesterolemia.

M. Yamagishi, H. Mabuchi, A. Nohara, 2017, Journal of clinical lipidology.

Serum Triglycerides and Atherosclerotic Cardiovascular Disease: Insights from Clinical and Genetic Studies

A. Nohara, M. Kawashiri, H. Tada, 2018, Nutrients.

Molecular and functional characterization of familial chylomicronemia syndrome.

K. Hayashi, M. Yamagishi, H. Mabuchi, 2017, Atherosclerosis.

Effect of common methylenetetrahydrofolate reductase gene mutation on coronary artery disease in familial hypercholesterolemia.

H. Mabuchi, A. Nohara, Akihiro Inazu, 2000, The American journal of cardiology.

Attainment of the low-density lipoprotein cholesterol treatment target and prognosis of heterozygous familial hypercholesterolemia.

A. Nohara, M. Kawashiri, H. Tada, 2023, Atherosclerosis.

Cholesterol-years score is associated with development of senile degenerative aortic stenosis in heterozygous familial hypercholesterolemia.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2006, Journal of atherosclerosis and thrombosis.

Impact of providing genetics-based future cardiovascular risk on LDL-C in patients with familial hypercholesterolemia.

A. Nohara, M. Kawashiri, H. Tada, 2023, Journal of clinical lipidology.

Coronary Artery and Carotid Artery Plaques in Patients With Heterozygous Familial Hypercholesterolemia

A. Nohara, M. Kawashiri, H. Tada, 2023, JACC: Advances.

Functional Characterization of Rare Variants Implicated in Susceptibility to Lone Atrial Fibrillation

K. Hayashi, M. Yamagishi, N. Makita, 2015, Circulation. Arrhythmia and electrophysiology.

Common Mutation of 5, 10-Methylenetetrahydrofolate Reductase Accelerates Coronary Artery Disease in Familial Hypercholesterolemia

H. Mabuchi, A. Nohara, Akihiro Inazu, 2000 .

Difference between fasting and nonfasting triglyceridemia; the influence of waist circumference.

M. Yamagishi, K. Miura, H. Mabuchi, 2009, Journal of atherosclerosis and thrombosis.

[Familial defective apolipoprotein B-100].

H. Mabuchi, A. Nohara, 1998, Ryoikibetsu shokogun shirizu.

A Rare Coincidence of Sitosterolemia and Familial Mediterranean Fever Identified by Whole Exome Sequencing.

K. Hayashi, M. Yamagishi, Y. Toyoshima, 2016, Journal of atherosclerosis and thrombosis.

Molecular genetic epidemiology of homozygous familial hypercholesterolemia in the Hokuriku district of Japan.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2011, Atherosclerosis.

Clinical Characteristics of Homozygous Familial Hypercholesterolemia in Japan

S. Yamashita, K. Matsuki, T. Miida, 2023, JACC. Asia.

Impact of the severe familial hypercholesterolemia status on atherosclerotic risks

A. Nohara, M. Kawashiri, S. Usui, 2023, Scientific reports.

IMPACT OF OUT-STENT PLAQUE VOLUME ON IN-STENT INTIMAL HYPERPLASIA: RESULTS FROM SERIAL VOLUMETRIC ANALYSIS WITH HIGH-GAIN INTRAVASCULAR ULTRASOUND

K. Hayashi, M. Yamagishi, A. Nohara, 2011 .

A novel method for determining functional LDL receptor activity in familial hypercholesterolemia: application of the CD3/CD28 assay in lymphocytes.

M. Yamagishi, H. Mabuchi, J. Kobayashi, 2009, Clinica chimica acta; international journal of clinical chemistry.

Abstract 18143: Impact of FMO3 Gene Loss-of-Function Variants on Coronary Artery Disease in Japanese

M. Yamagishi, H. Mabuchi, A. Nohara, 2014 .

Cholesteryl ester transfer protein inhibitor (JTT-705) and the development of atherosclerosis in rabbits with severe hypercholesterolaemia.

A. Nohara, T. Higashikata, Akihiro Inazu, 2002, Clinical science.

Cholesteryl Ester Transfer Protein (CETP) Deficiency and CETP Inhibitors

H. Mabuchi, A. Nohara, Akihiro Inazu, 2014, Molecules and cells.