P. Roques

发表

Deficits in cerebral glucose metabolism demonstrated by positron emission tomography in individuals at risk of familial Alzheimer's disease

Richard S. J. Frackowiak, R. Frackowiak, M. Rossor, 1995, Neuroscience Letters.

Complete analysis of the presenilin 1 gene in early onset Alzheimer's disease

M. Adams, J. Venter, J. Hardy, 1996, Neuroreport.

Screening for mutations in the open reading frame and promoter of the beta-amyloid precursor protein gene in familial Alzheimer's disease: identification of a further family with APP717 Val-->Ile.

J. Hardy, M. Rossor, R. Tanzi, 1992, Human molecular genetics.

CONFIRMATION THAT THE APOLIPOPROTEIN E4 ALLELE IS ASSOCIATED WITH LATE-ONSET, FAMILIAL ALZHEIMERS-DISEASE

J. Hardy, M. Rossor, J. Collinge, 1993 .

The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

M. Adams, N. Fox, J. Venter, 1995, Nature Genetics.

Clinical and Pathologic Features of Chromosome 21‐Linked Familial Alzheimer's Disease

J. Hardy, P. Lantos, M. Rossor, 1991, Annals of the New York Academy of Sciences.

THE MOLECULAR-GENETICS OF ALZHEIMERS-DISEASE

Martin N. Rossor, Robert Williamson, Ja Hardy, 1989 .

Familial dementia with swollen achromatic neurons and corticobasal inclusion bodies: a clinical and pathological study

P. Lantos, M. Rossor, P. Roques, 1996, Journal of the Neurological Sciences.

PRESYMPTOMATIC DEFICITS IN INDIVIDUALS AT RISK OF FAMILIAL ALZHEIMERS-DISEASE - A POSITRON EMISSION TOMOGRAPHY STUDY

R. Frackowiak, M. Rossor, A. Kennedy, 1994 .

Pathogenic presenilin 1 mutations (P436S & I143F) in early-onset Alzheimer's disease in the UK. Mutations in brief no. 223. Online.

Nick C Fox, M. Rossor, J. Collinge, 1999 .

Pathogenic presenilin 1 mutations (P436S & I143F) in early‐onset Alzheimer's disease in the UK

Nick C Fox, M. Palmer, M. Rossor, 1999, Human mutation.

Sequencing of exons 16 and 17 of the β-amyloid precursor protein gene in 14 families with early onset Alzheimer's disease fails to reveal mutations in the β-amyloid sequence

J. Hardy, M. Rossor, A. Goate, 1991, Neuroscience Letters.

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

M. Pericak-Vance, J. Hardy, M. Rossor, 1991, Nature.

Platelet serotonin content and plasma tryptophan in peri‐ and postmenopausal women: variations with plasma oestrogen levels and depressive symptoms

P. Boyer, P. Roques, P. Guicheney, 1988 .

Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene

J. Hardy, M. Rossor, A. Goate, 1991, Nature.

Platelet serotonin content and plasma tryptophan in peri- and postmenopausal women: variations with plasma oestrogen levels and depressive symptoms.

P. Boyer, P. Roques, P. Guicheney, 1988, European journal of clinical investigation.

PREDISPOSING LOCUS FOR ALZHEIMER'S DISEASE ON CHROMOSOME 21

Martin Farrall, M. Owen, M. Farrall, 1989, The Lancet.

A mutation in Alzheimer's disease destroying a splice acceptor site in the presenilin-1 gene

M. Adams, J. Hardy, M. Rossor, 1995, Neuroreport.

Chromosome 14 familial Alzheimer’s disease: the clinical and neuropathological characteristics of a family with a leucine→serine (L250S) substitution at codon 250 of the presenilin 1 gene

Nick C Fox, J. Hardy, M. Rossor, 1998, Journal of neurology, neurosurgery, and psychiatry.

Clinicopathological features of familial Alzheimer's disease associated with the M139V mutation in the presenilin 1 gene. Pedigree but not mutation specific age at onset provides evidence for a further genetic factor.

Nick C Fox, J. Hardy, P. Lantos, 1997, Brain : a journal of neurology.

Genetic Variability and Alzheimer’s Disease

J. Hardy, M. Rossor, A. Goate, 1994 .

Alzheimer’s Disease and Chromosome 21

J. Hardy, M. Rossor, R. Williamson, 1989 .

Clinical comparison of Alzheimer's disease in pedigrees with the codon 717 Val→Ile mutation in the amyloid precursor protein gene

Toru Shimizu, A. Roses, P. Lantos, 1993, Neurobiology of Aging.

Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region.

M. Rossor, A. Delacourte, A. Evans, 1994, Human molecular genetics.

Evidence that the APOE locus influences rate of disease progression in late onset familial Alzheimer's Disease but is not causative.

M. Rossor, R. Duara, P. Roques, 1995, American journal of medical genetics.

Apolipoprotein E alleles but neither apolipoprotein B nor apolipoprotein AI/CIII alleles are associated with late onset, familial Alzheimer's disease

J. Hardy, M. Rossor, J. Collinge, 1995, Neuroscience Letters.

Familial Alzheimer's disease. A pedigree with a mis-sense mutation in the amyloid precursor protein gene (amyloid precursor protein 717 valine-->glycine).

R. Frackowiak, J. Hardy, E. Warrington, 1993, Brain : a journal of neurology.

Lewy bodies in the brain of two members of a family with the 717 (Val to Ile) mutation of the amyloid precursor protein gene

P. Lantos, M. Rossor, C. Clelland, 1994, Neuroscience Letters.

Chromosome 14 linked familial Alzheimer's disease. A clinico-pathological study of a single pedigree.

R. Frackowiak, D. Neary, J. Stevens, 1995, Brain : a journal of neurology.

Confirmation that familial clustering and age of onset in late onset Alzheimer's disease are determined at the apolipoprotein E locus

J. Hardy, M. Rossor, J. Collinge, 1994, Neuroscience Letters.

THE MOLECULAR-GENETICS OF ALZHEIMERS-DISEASE

M. Rossor, R. Williamson, M. Owen, 1989 .

Slowing the progression of Alzheimer disease: monitoring progression.

Nick C Fox, P A Freeborough, N C Fox, 1997, Alzheimer disease and associated disorders.

Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder

I. Rainero, J. L. Haines, J. A. Hardy, 1990, Nature.

Genetics of Alzheimer's disease.

M. Farrall, M. Rossor, A. Goate, 1990 .

Molecular genetics of Alzheimer's disease.

M. Owen, M. Owen, P. Roques, 1989, Biochemical Society transactions.

PREDISPOSING LOCUS FOR ALZHEIMER'S DISEASE ON CHROMOSOME 21

M. Owen, M. Farrall, M. Rossor, 1989, The Lancet.