N. Kruse

发表

Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates

N. Rougier, E. Bézard, J. Obeso, 2020, Science Advances.

Characterizing mild cognitive impairment in incident Parkinson disease

T. Robbins, R. Barker, J. O'Brien, 2014, Neurology.

Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in non-human primates

N. Rougier, E. Bézard, J. Obeso, 2019, bioRxiv.

Reduction of Menkes mRNA and copper in leukocytes of patients with primary adult‐onset dystonia

D. Berg, M. Naumann, A. Weishaupt, 2001, Annals of neurology.

Validation of electrochemiluminescence assays for highly sensitive and reproducible quantification of α-synuclein in cerebrospinal fluid.

B. Mollenhauer, N. Kruse, O. El‐Agnaf, 2017, Bioanalysis.

Validation of a commercially available enzyme-linked immunoabsorbent assay for the quantification of human α-Synuclein in cerebrospinal fluid.

B. Mollenhauer, N. Kruse, 2015, Journal of immunological methods.

Systematic Assessment of 10 Biomarker Candidates Focusing on α‐Synuclein‐Related Disorders

B. Mollenhauer, J. Cedarbaum, R. Barbour, 2021, Movement disorders : official journal of the Movement Disorder Society.

Impaired maturation and altered regulatory function of plasmacytoid dendritic cells in multiple sclerosis.

R. Gold, K. Selmaj, K. Toyka, 2006, Brain : a journal of neurology.

Heterogeneity of T-cell receptor usage in experimental autoimmune neuritis in the Lewis rat.

R. Gold, A. Weishaupt, A. Theofilopoulos, 1999, Brain : a journal of neurology.

CTLA4 exon 1 dimorphism is associated with primary progressive multiple sclerosis

P. Rieckmann, N. Kruse, M. Mäurer, 2002, Journal of Neuroimmunology.

Quantification of cytokine mRNA expression by RT PCR in samples of previously frozen blood.

P. Rieckmann, K. Toyka, N. Kruse, 1997, Journal of immunological methods.

Genetic polymorphism of the tumor necrosis factor (TNF)-alpha promoter region in families with localized early-onset periodontitis.

P. Rieckmann, L. Shapira, A. Stabholz, 2001, Journal of periodontal research.

A polymorphism in the human cytotoxic T-lymphocyte antigen 4 (CTLA4) gene (exon 1 +49) alters T-cell activation

P. Rieckmann, S. Wiese, N. Kruse, 2002, Immunogenetics.

Genomic NGFB variation and multiple sclerosis in a case control study

R. Gold, J. Epplen, N. Kruse, 2008, BMC Medical Genetics.

Gene polymorphism at position –308 of the tumor necrosis factor α promotor is not associated with disease progression in multiple sclerosis patients

K. Kyriallis, P. Rieckmann, K. Toyka, 1999, Journal of Neurology.

Evaluation of diagnostic relevance of mRNA levels in peripheral blood: predictive value for mortality in hemodialysis patients.

H. Kolb, W. Scherbaum, C. Herder, 2004, Cytokine.

Conversion of human interleukin‐4 into a high affinity antagonist by a single amino acid replacement.

W. Sebald, N. Kruse, H. Tony, 1992, The EMBO journal.

Baseline Cerebrospinal Fluid α-Synuclein in Parkinson’s Disease Is Associated with Disease Progression and Cognitive Decline

B. Mollenhauer, D. Varges, I. Zerr, 2022, Diagnostics.

Cell stress molecules in the skeletal muscle of GNE myopathy

I. Nishino, A. Wrede, N. Kruse, 2013, BMC Neurology.

Modulation of cytokine mRNA expression by brain-derived neurotrophic factor and nerve growth factor in human immune cells

F. Weber, R. Gold, P. Rieckmann, 2003, Neuroscience Letters.

Validation of a quantitative cerebrospinal fluid alpha-synuclein assay in a European-wide interlaboratory study

K. Blennow, G. Frisoni, M. Tsolaki, 2015, Neurobiology of Aging.

HLA-DRB5*0101 and -DRB1*1501 expression in the multiple sclerosis-associated HLA-DR15 haplotype

Deric M. Park, Roland Martin, N. Kruse, 2005, Journal of Neuroimmunology.

Soluble vascular cell adhesion molecule (VCAM) is associated with treatment effects of Interferon beta-1b in patients with Secondary Progressive Multiple Sclerosis

C. Polman, H. Hartung, F. Dahlke, 2005, Journal of Neurology.

Anesthesia triggers drug delivery to experimental glioma in mice by hijacking caveolar transport

J. Frahm, W. Möbius, C. Stadelmann, 2021, Neuro-oncology advances.

Leukemia Inhibitory Factor Deficiency Modulates the Immune Response and Limits Autoimmune Demyelination: A New Role for Neurotrophic Cytokines in Neuroinflammation1

R. Ransohoff, R. Gold, B. Holtmann, 2008, The Journal of Immunology.

Leukemia Inhibitory Factor Deficiency Modulates the Immune Response and Limits Autoimmune Demyelination : A New Role for Neurotrophic Cytokines in Neuroinflammation 1

R. Ransohoff, R. Gold, B. Holtmann, 2008 .

Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis.

R. Gold, A. Weishaupt, K. Toyka, 2005, Cellular immunology.

Characterization of early immunological responses in primary cultures of differentially activated human peripheral mononuclear cells.

P. Rieckmann, K. Toyka, N. Kruse, 2001, Journal of immunological methods.

Altered innate immune response of plasmacytoid dendritic cells in multiple sclerosis

R. Gold, K. Selmaj, K. Toyka, 2009, Clinical and experimental immunology.

Short communication CTLA4 exon 1 dimorphism is associated with primary progressive multiple sclerosis

P. Rieckmann, N. Kruse, M. Mäurer, 2002 .

Genetic variation at position –1082 of the interleukin 10 (IL10) promotor and the outcome of multiple sclerosis

P. Rieckmann, K. Toyka, R. Giess, 2000, Journal of Neuroimmunology.

Neurofilament light chains in serum as biomarkers of axonal damage in early MS lesions: a histological–serological correlative study

W. Brück, N. Kruse, I. Metz, 2022, Journal of Neurology.

Natalizumab analogon therapy is effective in a B cell‐dependent multiple sclerosis model

W. Brück, S. Nessler, N. Kruse, 2015, Neuropathology and applied neurobiology.

Evidence for shoulder girdle dystonia in selected patients with cervical disc prolapse

D. Berg, M. Naumann, P. Rieckmann, 2002, Movement disorders : official journal of the Movement Disorder Society.

Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson’s Disease Progression

A. Singleton, A. Toga, D. Galasko, 2020, Movement disorders : official journal of the Movement Disorder Society.

A First Tetraplex Assay for the Simultaneous Quantification of Total α-Synuclein, Tau, β-Amyloid42 and DJ-1 in Human Cerebrospinal Fluid

H. Vanderstichele, B. Mollenhauer, E. Vanmechelen, 2016, PloS one.

A Practical Guide to Immunoassay Method Validation

Tormod Fladby, Henrik Zetterberg, Ulf Andreasson, 2015, Front. Neurol..

Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis.

H. Neumann, R. Gold, E. Gerhardt, 2010, Brain : a journal of neurology.

Differential expression of BDNF mRNA splice variants in mouse brain and immune cells

R. Gold, A. Chan, N. Kruse, 2007, Journal of Neuroimmunology.

Effects of Oncostatin M on Human Cerebral Endothelial Cells and Expression in Inflammatory Brain Lesions

W. Brück, T. Kuhlmann, P. Rieckmann, 2001, Journal of neuropathology and experimental neurology.

TREM2 expression in the brain and biological fluids in prion diseases

K. Blennow, B. Mollenhauer, J. D. del Río, 2021, Acta Neuropathologica.

Molecular Alterations in the Cerebellum of Sporadic Creutzfeldt–Jakob Disease Subtypes with DJ-1 as a Key Regulator of Oxidative Stress

B. Mollenhauer, I. Zerr, F. Llorens, 2016, Molecular Neurobiology.

Evaluation of α-synuclein as a novel cerebrospinal fluid biomarker in different forms of prion diseases

B. Mollenhauer, P. Liberski, D. Varges, 2017, Alzheimer's & Dementia.

Validation of α-Synuclein as a CSF Biomarker for Sporadic Creutzfeldt-Jakob Disease

A. Karch, B. Mollenhauer, P. Liberski, 2017, Molecular Neurobiology.

Cerebrospinal α-synuclein in α-synuclein aggregation disorders: tau/α-synuclein ratio as potential biomarker for dementia with Lewy bodies

B. Mollenhauer, D. Varges, I. Zerr, 2016, Journal of Neurology.

Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates.

E. Bézard, J. Obeso, M. Herrero, 2020, Brain : a journal of neurology.

ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis.

X. Montalban, F. Paul, J. Dörr, 2009, Brain : a journal of neurology.

Blood Contamination in CSF and Its Impact on Quantitative Analysis of Alpha-Synuclein

B. Mollenhauer, A. Linden, L. Tönges, 2020, Cells.

Antibody‐based methods for the measurement of α‐synuclein concentration in human cerebrospinal fluid – method comparison and round robin study

K. Blennow, L. Shaw, H. Vanderstichele, 2018, Journal of neurochemistry.

Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson’s disease and dementia with Lewy bodies

B. Mollenhauer, N. Kruse, A. Schneider, 2015, Brain : a journal of neurology.

Quantification of CSF biomarkers using an electrochemiluminescence-based detection system in the differential diagnosis of AD and sCJD

B. Mollenhauer, I. Zerr, F. Llorens, 2015, Journal of Neurology.

Recommendations to standardize Pre-analytical confounding factors in Alzheimer ’ s and Parkinson ’ s disease CSF biomarkers : an update

H. Hampel, S. Engelborghs, S. Lehmann, 2015 .

Recommendations to standardize preanalytical confounding factors in Alzheimer's and Parkinson's disease cerebrospinal fluid biomarkers: an update.

J. Molinuevo, P. Visser, H. Hampel, 2012, Biomarkers in medicine.

Development of electrochemiluminescence-based singleplex and multiplex assays for the quantification of α-synuclein and other proteins in cerebrospinal fluid.

B. Mollenhauer, W. Schulz-Schaeffer, N. Kruse, 2012, Methods.

Influenza vaccination in MS

V. ter meulen, P. Rieckmann, K. Toyka, 2001, Neurology.

Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation

S. Kügler, B. Mollenhauer, A. Giese, 2015, Acta Neuropathologica.

Interlaboratory validation of cerebrospinal fluid α-synuclein quantification in the diagnosis of sporadic Creutzfeldt-Jakob disease

K. Blennow, S. Lehmann, B. Mollenhauer, 2018, Alzheimer's & dementia.

Diagnostic accuracy of cerebrospinal fluid biomarkers in genetic prion diseases

G. Escaramís, B. Mollenhauer, P. Liberski, 2022, Brain : a journal of neurology.

Systematic Comparison of the Effects of Alpha-synuclein Mutations on Its Oligomerization and Aggregation

G. Braus, B. Mollenhauer, S. Rizzoli, 2014, PLoS genetics.

Two distinct functional sites of human interleukin 4 are identified by variants impaired in either receptor binding or receptor activation.

W. Sebald, N. Kruse, H. Tony, 1993, The EMBO journal.

Molecular Analysis of Cytokines and Cytokine Receptors

P. Rieckmann, N. Kruse, 2006 .

Expression of tumor necrosis factor-α and interferon-γ mRNA in blood cells correlates with depression scores during an acute attack in patients with multiple sclerosis

P. Rieckmann, K. Kahl, H. Faller, 2002, Psychoneuroendocrinology.

Glucocorticoid effects on endothelial barrier function in the murine brain endothelial cell line cEND incubated with sera from patients with multiple sclerosis

R. Gold, A. Chan, N. Roewer, 2010, Multiple sclerosis.

Multicenter immunoassay validation of cerebrospinal fluid neurofilament light: a biomarker for neurodegeneration.

B. Lawlor, B. Mollenhauer, H. Zetterberg, 2016, Bioanalysis.

Impact of the Asp299Gly polymorphism in the toll-like receptor 4 (tlr-4) gene on disease course of multiple sclerosis

B. Hemmer, P. Rieckmann, K. Toyka, 2005, Journal of Neuroimmunology.

Serial analysis of cytokine mRNA profiles in whole blood samples from patients with early multiple sclerosis

P. Rieckmann, K. Toyka, K. Kahl, 2002, Journal of the Neurological Sciences.

Expression of tumor necrosis factor-alpha and interferon-gamma mRNA in blood cells correlates with depression scores during an acute attack in patients with multiple sclerosis.

P. Rieckmann, K. Kahl, H. Faller, 2002, Psychoneuroendocrinology.

Quantification of Alpha-Synuclein in Biological Fluids by Electrochemiluminescence-Based Detection.

B. Mollenhauer, N. Kruse, 2019, Methods in molecular biology.

Quantified CSF antibody reactivity against myelin in multiple sclerosis

C. Kremser, L. Kappos, K. Willecke, 2015, Annals of clinical and translational neurology.

Cross-Sectional and Longitudinal Validation of Serum Neurofilament Light Chain (NfL) as a Biomarker of Parkinson’s Disease Progression

A. Singleton, A. Toga, D. Galasko, 2019, bioRxiv.

Influenza vaccination in MS: Absence of T-cell response against white matter proteins

K. Toyka, V. ter meulen, P. Rieckmann, 2001 .

Variations in cytokine mRNA expression during normal human pregnancy

P. Rieckmann, N. Kruse, K. Toyka, 2000, Clinical and experimental immunology.