V. Guthrie

发表

Evaluation of machine learning methods to predict peptide binding to MHC Class I proteins

Collin Tokheim, Rachel Karchin, Victor E. Velculescu, 2017, bioRxiv.

Evolution of Neoantigen Landscape during Immune Checkpoint Blockade in Non-Small Cell Lung Cancer.

C. Zahnow, S. Baylin, R. Scharpf, 2017, Cancer discovery.

Coevolution Network Models Predict the Impact of Multiple Mutations on Protein Function

V. Guthrie, 2016 .

UC Office of the President Recent Work Title Network Analysis of Protein Adaptation : Modeling the Functional Impact of Multiple Mutations Permalink

David L. Masica, R. Karchin, D. Masica, 2018 .

Prediction of peptide binding to MHC Class I proteins in the age of deep learning

Rachel Karchin, Rohit Bhattacharya, Ashok Sivakumar, 2017 .

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

T. Pawlik, L. Wood, K. Kinzler, 2013, Nature Genetics.

Network Models of TEM β-Lactamase Mutations Coevolving under Antibiotic Selection Show Modular Structure and Anticipate Evolutionary Trajectories

Rachel Karchin, Violeta Beleva Guthrie, Jennifer Allen, 2011, PLoS Comput. Biol..

Exome sequencing identifies frequent inactivating mutations in BAP 1 , ARID 1 A and PBRM 1 in intrahepatic cholangiocarcinomas

Aldo, Nickolas, Scarpa, 2014 .

Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing.

David L. Masica, R. Yelensky, R. Karchin, 2015, Annals of oncology : official journal of the European Society for Medical Oncology.

Validation of a Circulating Tumor DNA‐Based Next‐Generation Sequencing Assay in a Cohort of Patients with Solid tumors: A Proposed Solution for Decentralized Plasma Testing

Samuel V. Angiuoli, O. Elemento, A. Sboner, 2021, The Oncologist.

A Probabilistic Model to Predict Clinical Phenotypic Traits from Genome Sequencing

Cheng Wang, Biao Li, Sean D. Mooney, 2014, PLoS Comput. Biol..

Gemcitabine and cisplatin plus durvalumab with or without tremelimumab in chemotherapy-naive patients with advanced biliary tract cancer: an open-label, single-centre, phase 2 study.

M. Rebelatto, J. W. Kim, P. Mccoon, 2022, The lancet. Gastroenterology & hepatology.

Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing.

R. Yelensky, R. Karchin, C. Tokheim, 2015 .

SubClonal Hierarchy Inference from Somatic Mutations: Automatic Reconstruction of Cancer Evolutionary Trees from Multi-region Next Generation Sequencing

Daniel Q. Naiman, Rachel Karchin, Noushin Niknafs, 2015, bioRxiv.

Abstract NG01: Evolution of neoantigen landscape during immune checkpoint blockade in non-small cell lung cancer

C. Zahnow, S. Baylin, R. Scharpf, 2017 .

CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods

Silvio C. E. Tosatto, Julius O. B. Jacobsen, Nicholas A. Sinnott-Armstrong, 2024, Genome biology.

Genomic characterization of malignant progression in neoplastic pancreatic cysts

R. Scharpf, L. Wood, V. Velculescu, 2020, Nature Communications.

CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods

Nicholas A. Sinnott-Armstrong, Jonathan M. Mudge, Hui Ting Grace Yeo, 2022, Genome biology.

68O Impact of mutation status on efficacy outcomes in TOPAZ-1: A phase III study of durvalumab (D) or placebo (PBO) plus gemcitabine and cisplatin (+GC) in advanced biliary tract cancer (BTC)

V. Guthrie, S. Qin, D. Tougeron, 2022, Annals of Oncology.