Julianty Frost

发表

Hypoxia induces rapid changes to histone methylation and reprograms chromatin

P. Schofield, S. Rocha, M. Batie, 2019, Science.

RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response.

S. Rocha, Julianty Frost, A. Ciulli, 2019, Wellcome open research.

Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase: Structure–Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrroli

K. Read, S. Rocha, Julianty Frost, 2017, Journal of medicinal chemistry.

Hypoxia induces rapid changes to histone methylation reprogramming chromatin for the cellular response

P. Schofield, S. Rocha, M. Batie, 2019, bioRxiv.

Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition

P. Grandi, K. Read, M. Bantscheff, 2016, Nature Communications.

Roles of HIF and 2-Oxoglutarate-Dependent Dioxygenases in Controlling Gene Expression in Hypoxia

S. Rocha, M. Batie, Julianty Frost, 2021, Cancers.

Roles Of HIF and 2-Oxoglutarate Dependent Enzymes in Controlling Gene Expression In Hypoxia

S. Rocha, M. Batie, Julianty Frost, 2020 .

Transcription | Regulation of Gene Transcription by Hypoxia-Inducible Factor 1α

S. Rocha, Julianty Frost, James W. Wilson, 2020 .

Regulation of chromatin accessibility by hypoxia and HIF

S. Rocha, M. Batie, Julianty Frost, 2022, bioRxiv.

Von Hippel–Lindau (VHL) small-molecule inhibitor binding increases stability and intracellular levels of VHL protein

S. Rocha, Julianty Frost, A. Ciulli, 2021, The Journal of biological chemistry.

VHL ligand binding increases intracellular level of VHL

S. Rocha, Julianty Frost, A. Ciulli, 2021, bioRxiv.

RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response.

Ciulli, S. Rocha, Julianty Frost, 2019, Wellcome open research.